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Overview

ID MAG00232
Name CH2_bin.1
Sample SMP0008
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Casimicrobiaceae
Genus CAIWHR01
Species
Assembly information
Completeness (%) 89.75
Contamination (%) 1.55
GC content (%) 67.0
N50 (bp) 7,313
Genome size (bp) 2,566,233

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2643

Gene name Description KEGG GOs EC E-value Score Sequence
CH2_k127_10128562_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 2.434e-242 753.0
CH2_k127_10128562_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 366.0
CH2_k127_10128562_2 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000009714 263.0
CH2_k127_10128562_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000001058 177.0
CH2_k127_1018881_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0 1203.0
CH2_k127_1018881_1 AAA domain K03582 - 3.1.11.5 0.0 1195.0
CH2_k127_1018881_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 5.322e-196 642.0
CH2_k127_1018881_3 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 0.000000000000000000000000000000000000000000000000000000000000003822 231.0
CH2_k127_1018881_4 RelE-like toxin of type II toxin-antitoxin system HigB - - - 0.0000000000000000000000004908 107.0
CH2_k127_1018881_5 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.000000000000000001324 93.0
CH2_k127_10290800_0 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 2.211e-199 624.0
CH2_k127_10290800_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 548.0
CH2_k127_1029650_0 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 367.0
CH2_k127_1029650_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 326.0
CH2_k127_1029650_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000004124 232.0
CH2_k127_1029650_3 Belongs to the HAD-like hydrolase superfamily. PhnX family K05306 - 3.11.1.1 0.0000000000000000000000000000000000000000008153 158.0
CH2_k127_1029650_4 Protein of unknown function (DUF3667) - - - 0.0000000000000000000000000000000000000001438 161.0
CH2_k127_1029650_5 - - - - 0.00000000000000000004338 96.0
CH2_k127_1029650_6 TRAP-type C4-dicarboxylate transport system, large permease - - - 0.000005367 48.0
CH2_k127_10297420_0 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 3.755e-228 715.0
CH2_k127_10297420_1 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 585.0
CH2_k127_10297420_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 574.0
CH2_k127_10297420_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 475.0
CH2_k127_10297420_4 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 361.0
CH2_k127_10324171_0 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 8.945e-319 992.0
CH2_k127_10324171_1 Tripartite tricarboxylate transporter TctA family - - - 3.081e-253 789.0
CH2_k127_10324171_10 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004299 258.0
CH2_k127_10324171_11 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000002138 235.0
CH2_k127_10324171_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000003237 194.0
CH2_k127_10324171_13 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000000000002474 147.0
CH2_k127_10324171_14 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000001027 117.0
CH2_k127_10324171_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000001744 71.0
CH2_k127_10324171_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.454e-252 780.0
CH2_k127_10324171_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.078e-239 746.0
CH2_k127_10324171_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 513.0
CH2_k127_10324171_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 509.0
CH2_k127_10324171_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 319.0
CH2_k127_10324171_7 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 299.0
CH2_k127_10324171_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005152 292.0
CH2_k127_10324171_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000008839 269.0
CH2_k127_10357883_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 9.842e-206 660.0
CH2_k127_10357883_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 353.0
CH2_k127_10357883_2 binding-protein-dependent transport systems inner membrane component K13894 - - 0.0000000000006136 74.0
CH2_k127_10363045_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 4.302e-209 659.0
CH2_k127_10363045_1 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000000002044 206.0
CH2_k127_10363045_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000002014 193.0
CH2_k127_10363045_3 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.0000000000000000000000000000000000002798 160.0
CH2_k127_10363045_4 Beta/gamma crystallins - - - 0.0000000000000000000000000004164 121.0
CH2_k127_1038385_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 449.0
CH2_k127_1038385_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 359.0
CH2_k127_1038385_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 301.0
CH2_k127_10405562_0 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 485.0
CH2_k127_10405562_1 - - - - 0.000000000000000000000000000000000000000000000000007128 186.0
CH2_k127_10405562_2 cell redox homeostasis - - - 0.00000000000000000005627 91.0
CH2_k127_10450463_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 455.0
CH2_k127_10450463_1 - - - - 0.000000000000000000000000000000006082 131.0
CH2_k127_10450463_2 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000001436 106.0
CH2_k127_10457947_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 544.0
CH2_k127_10457947_1 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000775 480.0
CH2_k127_10457947_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000003276 267.0
CH2_k127_10457947_3 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000003744 210.0
CH2_k127_10457947_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000008743 160.0
CH2_k127_10457947_5 Pfam:DUF1049 K08992 - - 0.000003364 53.0
CH2_k127_10470448_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 578.0
CH2_k127_10470448_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 345.0
CH2_k127_10470448_2 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000007003 117.0
CH2_k127_10470448_3 Isochorismatase family K08281 - 3.5.1.19 0.00000000000003598 73.0
CH2_k127_10472095_0 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 7.346e-211 666.0
CH2_k127_10472095_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.436e-205 647.0
CH2_k127_10472095_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 565.0
CH2_k127_10472095_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 472.0
CH2_k127_10472095_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 310.0
CH2_k127_10472095_5 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003543 276.0
CH2_k127_10472095_6 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000001772 243.0
CH2_k127_10472095_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000293 157.0
CH2_k127_10472095_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000001813 111.0
CH2_k127_10478893_0 PFAM aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 530.0
CH2_k127_10478893_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 497.0
CH2_k127_10478893_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 304.0
CH2_k127_10478893_3 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000001797 262.0
CH2_k127_10478893_4 OmpA family K03286 - - 0.00000000000000000000000000000000000000000000009703 172.0
CH2_k127_10478893_5 Sodium Bile acid symporter family - - - 0.0000000000009206 73.0
CH2_k127_10478893_6 Type II secretion system protein C K02452 - - 0.0002005 53.0
CH2_k127_10517809_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 8.944e-320 987.0
CH2_k127_10517809_1 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 491.0
CH2_k127_10517809_2 (ABC) transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 376.0
CH2_k127_10517809_3 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 386.0
CH2_k127_1052900_0 PFAM PfkB domain protein K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 352.0
CH2_k127_1052900_1 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000002522 237.0
CH2_k127_1052900_2 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.000000000000000000000000000000000000000000000000000000000000000000379 240.0
CH2_k127_1052900_3 molybdopterin-guanine dinucleotide biosynthesis protein b K03753 - - 0.0000000000000000000000000000000000000000000000000000000000004564 214.0
CH2_k127_1052900_4 SOS response associated peptidase (SRAP) - - - 0.0000000000000000000000000000000000000000000000004163 179.0
CH2_k127_1052900_5 - - - - 0.0000000000000000000000000000000000000000001045 166.0
CH2_k127_1052900_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000002722 103.0
CH2_k127_1052900_7 - - - - 0.00000000000000003095 84.0
CH2_k127_1052900_8 Dehydrogenase - - - 0.0000001041 59.0
CH2_k127_1052900_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.00001254 55.0
CH2_k127_10548588_0 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005806 283.0
CH2_k127_10548588_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008209 274.0
CH2_k127_10548588_2 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001229 263.0
CH2_k127_10548588_3 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005853 235.0
CH2_k127_10548588_4 - - - - 0.000000007043 57.0
CH2_k127_10548588_5 FR47-like protein - - - 0.0008114 50.0
CH2_k127_10561849_0 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.0000000000000000000000000000000000000000000000000000002634 202.0
CH2_k127_10561849_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.0000000000000000000000000000001785 125.0
CH2_k127_10561849_2 Glutathione S-transferase, N-terminal domain K11208 - - 0.000000000000000000000000002969 114.0
CH2_k127_10561849_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000438 57.0
CH2_k127_10595069_0 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 384.0
CH2_k127_10595069_1 Xylose isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 368.0
CH2_k127_10595069_2 helix_turn_helix isocitrate lyase regulation K05818 - - 0.00000000000000000000000000000000000000000000000000000000000000009161 228.0
CH2_k127_10595069_3 Aldo/keto reductase family K05882 - 1.1.1.91 0.000000000000000000000000000000000000000000000000000000000009347 211.0
CH2_k127_10602986_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.844e-307 968.0
CH2_k127_10602986_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 461.0
CH2_k127_10602986_2 Glutathione S-transferase, N-terminal domain K11208 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 294.0
CH2_k127_10602986_3 LexA DNA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004481 258.0
CH2_k127_10602986_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000004794 224.0
CH2_k127_10602986_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.0000000000000000000000000000000000000000000000008203 178.0
CH2_k127_1060459_0 Type II secretion system protein K K02460 - - 0.000000000000000000000000000000000000000000000002326 184.0
CH2_k127_1060459_1 fimbrial assembly K02461 - - 0.0000000000000000000000000225 121.0
CH2_k127_1062705_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.476e-291 910.0
CH2_k127_1062705_1 Proton-conducting membrane transporter - - - 1.929e-278 870.0
CH2_k127_1062705_2 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 1.252e-194 612.0
CH2_k127_1062705_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 448.0
CH2_k127_1062705_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000788 441.0
CH2_k127_1062705_5 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 314.0
CH2_k127_1064171_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 441.0
CH2_k127_1064171_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 364.0
CH2_k127_1064171_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000008852 168.0
CH2_k127_1064171_11 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000002105 157.0
CH2_k127_1064171_12 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000000000008524 157.0
CH2_k127_1064171_13 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000000001834 149.0
CH2_k127_1064171_14 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000004622 122.0
CH2_k127_1064171_15 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000003806 68.0
CH2_k127_1064171_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 310.0
CH2_k127_1064171_3 50S ribosomal protein L4 K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 293.0
CH2_k127_1064171_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005047 245.0
CH2_k127_1064171_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000001259 217.0
CH2_k127_1064171_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000001428 218.0
CH2_k127_1064171_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000000000000000001651 214.0
CH2_k127_1064171_8 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000117 171.0
CH2_k127_1064171_9 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000001197 169.0
CH2_k127_10650898_0 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 615.0
CH2_k127_10650898_1 amino acid transport system, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 318.0
CH2_k127_10650898_2 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000002352 128.0
CH2_k127_10673891_0 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000005754 195.0
CH2_k127_10673891_1 glycosylase K03649 - 3.2.2.28 0.000000000000000000000000000000000000000000000000005347 188.0
CH2_k127_10673891_2 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000006141 156.0
CH2_k127_10673891_3 glyoxalase III activity K00799 - 2.5.1.18 0.0000000000000000000000000000007021 129.0
CH2_k127_10673891_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000005853 78.0
CH2_k127_10721557_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 404.0
CH2_k127_10721557_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 294.0
CH2_k127_10721557_2 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000002715 181.0
CH2_k127_10721557_3 - - - - 0.000000000000000000000000000000002014 134.0
CH2_k127_10721557_4 Sporulation related domain - - - 0.000000000000000000000003697 113.0
CH2_k127_10766165_0 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000000000005819 133.0
CH2_k127_10766165_1 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000000000000000000005784 119.0
CH2_k127_10766165_2 nucleic acid-binding protein, contains PIN domain - - - 0.0000000000000000005409 94.0
CH2_k127_10766165_3 Bacterial transcriptional activator domain - - - 0.0000000000000001371 92.0
CH2_k127_10766165_4 prlF antitoxin for toxin YhaV_toxin - - - 0.00000000000005642 75.0
CH2_k127_10768211_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.624e-237 741.0
CH2_k127_10768211_1 cytochrome C oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 609.0
CH2_k127_10768211_2 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 371.0
CH2_k127_10768211_3 subunit II K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 336.0
CH2_k127_10768211_4 Transcriptional regulator crp fnr family K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 303.0
CH2_k127_10768211_5 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000001192 151.0
CH2_k127_10768211_6 FixH family K09926 - - 0.000000000000000000000000000003499 132.0
CH2_k127_10768211_7 - - - - 0.00000000000000000000000009633 115.0
CH2_k127_10768211_8 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000001796 87.0
CH2_k127_10768211_9 Cbb3-type cytochrome oxidase subunit K00407 - - 0.00001304 49.0
CH2_k127_10775436_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 403.0
CH2_k127_10775436_1 TRAP-type C4-dicarboxylate transport system, large permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 295.0
CH2_k127_10775436_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000001626 154.0
CH2_k127_10793782_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 395.0
CH2_k127_10793782_1 Domain of unknown function (DUF4743) - - - 0.00000000000000000000000000000000000000000000000000000000000000002978 233.0
CH2_k127_10797264_0 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000001546 267.0
CH2_k127_10797264_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000003306 201.0
CH2_k127_10797264_2 Tfp pilus assembly protein K02655 - - 0.000000000000000000000000000006789 134.0
CH2_k127_10797264_3 Type II transport protein GspH K08084 - - 0.000000000000000000000000002619 119.0
CH2_k127_10797264_4 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000002551 102.0
CH2_k127_10797264_5 type IV pilus modification protein PilV K02671 - - 0.0000000002256 72.0
CH2_k127_10810828_0 abc transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 317.0
CH2_k127_10810828_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003057 275.0
CH2_k127_10810828_2 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001009 270.0
CH2_k127_10810828_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000006457 166.0
CH2_k127_10810828_4 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.00000003061 54.0
CH2_k127_10846868_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 430.0
CH2_k127_10846868_1 Transcription factor zinc-finger - - - 0.0000000000000000000000000000000000128 144.0
CH2_k127_10846868_2 Modulates RecA activity K03565 - - 0.0000000000000000000001647 105.0
CH2_k127_10846868_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000003088 94.0
CH2_k127_10846868_4 - - - - 0.000000000001011 74.0
CH2_k127_1089776_0 Tripartite tricarboxylate transporter TctA family K07793 - - 4.532e-288 893.0
CH2_k127_1089776_1 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 1.56e-218 683.0
CH2_k127_1089776_2 Carbohydrate transport and metabolism K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 613.0
CH2_k127_1089776_3 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 441.0
CH2_k127_1089776_4 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 419.0
CH2_k127_1089776_5 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 322.0
CH2_k127_1089776_6 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002179 271.0
CH2_k127_1089776_7 Tripartite ATP-independent periplasmic transporter dctq component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001444 254.0
CH2_k127_1089776_8 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000000000000000000000000001147 232.0
CH2_k127_1089776_9 Tripartite tricarboxylate transporter TctB family - - - 0.00000005275 54.0
CH2_k127_10914129_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 547.0
CH2_k127_10914129_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 496.0
CH2_k127_10914129_2 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 476.0
CH2_k127_10914129_3 CbbX protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 449.0
CH2_k127_10914129_4 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000005204 234.0
CH2_k127_10914129_5 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000003962 183.0
CH2_k127_10914129_6 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000008587 123.0
CH2_k127_10926861_0 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 518.0
CH2_k127_10926861_1 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000787 233.0
CH2_k127_10984951_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.0 1020.0
CH2_k127_10984951_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000001205 180.0
CH2_k127_11018185_0 AcrB/AcrD/AcrF family - - - 0.0 1595.0
CH2_k127_11018185_1 Methionine synthase K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 608.0
CH2_k127_11018185_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 434.0
CH2_k127_11018185_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 399.0
CH2_k127_11018185_12 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 365.0
CH2_k127_11018185_13 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 326.0
CH2_k127_11018185_14 Pfam:Methyltransf_6 K10218 - 4.1.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 321.0
CH2_k127_11018185_15 Transcriptional regulator K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 295.0
CH2_k127_11018185_16 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001049 253.0
CH2_k127_11018185_17 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001228 242.0
CH2_k127_11018185_18 Protein of unknown function (DUF2652) - - - 0.000000000000000000000000000000000000000000000000000000000000000000375 236.0
CH2_k127_11018185_19 COG3119 Arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000002079 236.0
CH2_k127_11018185_2 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 570.0
CH2_k127_11018185_20 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000001451 205.0
CH2_k127_11018185_21 Protocatechuate 4,5-dioxygenase K04100 - 1.13.11.8 0.00000000000000000000000000000000000000000000000000002249 191.0
CH2_k127_11018185_22 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000000000007162 105.0
CH2_k127_11018185_3 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 537.0
CH2_k127_11018185_4 PrpF protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 532.0
CH2_k127_11018185_5 Extracellular liganD-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 518.0
CH2_k127_11018185_6 metal-dependent hydrolase of the TIM-barrel fold K10221 - 3.1.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 495.0
CH2_k127_11018185_7 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04099,K04101 - 1.13.11.57,1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 469.0
CH2_k127_11018185_8 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 469.0
CH2_k127_11018185_9 abc transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 461.0
CH2_k127_1107134_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 6.906e-289 893.0
CH2_k127_1107134_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.171e-268 839.0
CH2_k127_1107134_2 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000001656 201.0
CH2_k127_1107134_3 - - - - 0.0000000000000000000000000000000000000000000001006 178.0
CH2_k127_1107134_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000341 144.0
CH2_k127_1107134_5 Protein of unknown function (DUF2726) - - - 0.00004969 53.0
CH2_k127_11134773_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1065.0
CH2_k127_11134773_1 MCM2/3/5 family K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 345.0
CH2_k127_11134773_2 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000000000000000008723 173.0
CH2_k127_11134773_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000007103 143.0
CH2_k127_11134773_4 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000007351 135.0
CH2_k127_1121644_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 8.695e-219 685.0
CH2_k127_1121644_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 449.0
CH2_k127_1121644_10 NLP P60 protein - - - 0.000000000000000000000000000000000000000000006598 175.0
CH2_k127_1121644_11 Ankyrin repeat K06867 - - 0.0000000000000000000000000000000000000000008846 167.0
CH2_k127_1121644_12 pilus assembly protein PilZ K02676 - - 0.000000000000000000000005856 102.0
CH2_k127_1121644_13 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000006739 72.0
CH2_k127_1121644_2 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 370.0
CH2_k127_1121644_3 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 357.0
CH2_k127_1121644_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 339.0
CH2_k127_1121644_5 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 319.0
CH2_k127_1121644_6 squalene-associated FAD-dependent desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009978 286.0
CH2_k127_1121644_7 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000231 239.0
CH2_k127_1121644_8 SmpB protein K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000001578 232.0
CH2_k127_1121644_9 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000008744 184.0
CH2_k127_11256856_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 3.356e-195 632.0
CH2_k127_11256856_1 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 377.0
CH2_k127_11256856_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 347.0
CH2_k127_11256856_3 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.000000000000000000000000000000000000000000000000000000000007797 211.0
CH2_k127_11256856_4 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000009622 114.0
CH2_k127_11256856_5 Domain of unknown function (DUF4124) - - - 0.000004639 51.0
CH2_k127_11264746_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 434.0
CH2_k127_11264746_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 403.0
CH2_k127_11264746_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 372.0
CH2_k127_11264746_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 337.0
CH2_k127_11264746_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000003191 256.0
CH2_k127_11264746_5 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000006542 228.0
CH2_k127_11264746_6 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000000103 116.0
CH2_k127_11264746_7 CBS domain - - - 0.00000000000001152 74.0
CH2_k127_11264746_8 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000001697 81.0
CH2_k127_11318951_0 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000009007 188.0
CH2_k127_11318951_1 Secreted repeat of unknown function - - - 0.0000000000000000000000000000000000000000000000005958 181.0
CH2_k127_11318951_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000003753 159.0
CH2_k127_11318951_3 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.0000000001744 63.0
CH2_k127_11326332_0 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 564.0
CH2_k127_11326332_1 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000002221 169.0
CH2_k127_11326332_2 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000009495 138.0
CH2_k127_11354967_0 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 447.0
CH2_k127_11354967_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004014 272.0
CH2_k127_11354967_2 Shikimate kinase K00851 - 2.7.1.12 0.000000000000000000000000000000000000000000003517 170.0
CH2_k127_11354967_3 EamA-like transporter family - - - 0.000000000000000000000000003207 116.0
CH2_k127_11368323_0 Mannitol dehydrogenase Rossmann domain K00040 - 1.1.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 522.0
CH2_k127_11368323_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 333.0
CH2_k127_11368323_2 glucuronate isomerase K01812 - 5.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000266 246.0
CH2_k127_11383612_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 6.734e-321 993.0
CH2_k127_11383612_1 Belongs to the thiolase family K00632,K07550 - 2.3.1.16 6.551e-198 623.0
CH2_k127_11383612_2 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 537.0
CH2_k127_11383612_3 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 531.0
CH2_k127_11383612_4 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009982 507.0
CH2_k127_11383612_5 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003905 269.0
CH2_k127_11383612_6 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000006494 153.0
CH2_k127_11404823_0 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 6.979e-256 811.0
CH2_k127_11404823_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 344.0
CH2_k127_1143504_0 glutamine synthetase K01915 - 6.3.1.2 8.148e-260 806.0
CH2_k127_1143504_1 Domain of unknown function (DUF4124) - - - 0.000008867 58.0
CH2_k127_11469944_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1060.0
CH2_k127_11469944_1 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 7.154e-204 642.0
CH2_k127_11469944_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 607.0
CH2_k127_11469944_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 556.0
CH2_k127_11469944_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000003195 234.0
CH2_k127_11469944_5 COG3245 Cytochrome c5 - - - 0.00000000000000000000000000000000000000000000000000000000000007568 227.0
CH2_k127_11469944_6 - - - - 0.000000000000000000000000001943 124.0
CH2_k127_1147385_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 432.0
CH2_k127_1147385_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 426.0
CH2_k127_1147385_2 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.0000000000000008044 78.0
CH2_k127_11503708_0 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 375.0
CH2_k127_11503708_1 Acetyl-CoA carboxylase carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 325.0
CH2_k127_11503708_2 Bacterial transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000004709 213.0
CH2_k127_11503708_3 Methylmuconolactone methyl-isomerase - - - 0.00000000000000000000000000000000000000000001099 171.0
CH2_k127_11503708_4 DUF218 domain - - - 0.00000000000000000000000000000000001123 143.0
CH2_k127_11713170_0 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000005025 184.0
CH2_k127_11713170_1 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000000000000003385 179.0
CH2_k127_11728891_0 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 428.0
CH2_k127_11728891_1 Protein of unknown function (DUF1178) - - - 0.00000000000000000000000000000000002604 139.0
CH2_k127_11770978_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 557.0
CH2_k127_11770978_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 464.0
CH2_k127_11770978_2 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 446.0
CH2_k127_11770978_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 375.0
CH2_k127_11770978_4 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009428 255.0
CH2_k127_11770978_5 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000182 234.0
CH2_k127_11770978_6 Dodecin K09165 - - 0.0000000000000000000003744 102.0
CH2_k127_11770978_7 lipolytic protein G-D-S-L family - - - 0.000000000002088 70.0
CH2_k127_1177339_0 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001022 283.0
CH2_k127_1177339_1 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000009371 271.0
CH2_k127_1177339_2 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000006463 58.0
CH2_k127_11785306_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 586.0
CH2_k127_11785306_1 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 302.0
CH2_k127_11785306_2 amino acid ABC transporter K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 293.0
CH2_k127_11785306_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000007384 177.0
CH2_k127_11785306_4 - - - - 0.0000000000000000000000000000006944 124.0
CH2_k127_11785306_5 Lanthionine synthetase C-like protein - - - 0.00000000003396 69.0
CH2_k127_11810667_0 AAA ATPase domain - - - 2.698e-253 818.0
CH2_k127_11810667_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.437e-225 709.0
CH2_k127_11810667_10 Phosphoglycerate mutase family K08296 - - 0.00000000000000000000000000000000000000000000000000003084 191.0
CH2_k127_11810667_2 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 504.0
CH2_k127_11810667_3 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 480.0
CH2_k127_11810667_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 456.0
CH2_k127_11810667_5 phosphate transport system K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 441.0
CH2_k127_11810667_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 437.0
CH2_k127_11810667_7 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 417.0
CH2_k127_11810667_8 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 319.0
CH2_k127_11810667_9 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008383 249.0
CH2_k127_11818505_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 600.0
CH2_k127_11818505_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001505 281.0
CH2_k127_11818505_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000004417 154.0
CH2_k127_11818505_3 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000004157 87.0
CH2_k127_11821299_0 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000000000000000001073 219.0
CH2_k127_11821299_1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000002045 71.0
CH2_k127_11821299_2 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000384 72.0
CH2_k127_11821299_3 Hydrogenase expression formation protein K03605 - - 0.0000000009337 66.0
CH2_k127_11837007_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1024.0
CH2_k127_11837007_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.216e-229 726.0
CH2_k127_11837007_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 523.0
CH2_k127_11837007_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 446.0
CH2_k127_11837007_4 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 440.0
CH2_k127_11837007_5 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 366.0
CH2_k127_11837007_6 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000008599 186.0
CH2_k127_11837007_7 B12 binding domain K01849 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564 5.4.99.2 0.0000000000000000000000000000000000000000000000004982 178.0
CH2_k127_11837007_8 phenylacetic acid degradation protein paaD K02614 - - 0.00000000000000000000000000000000000004813 147.0
CH2_k127_11837007_9 CRP FNR family - - - 0.0002547 45.0
CH2_k127_1185442_0 PFAM Type II secretion system protein E K02454 - - 5.217e-210 668.0
CH2_k127_1185442_1 Aminotransferase K01845 - 5.4.3.8 0.000000000000000000000000000002037 121.0
CH2_k127_1185442_2 General secretion pathway protein K02455 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.00007062 45.0
CH2_k127_11903494_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1227.0
CH2_k127_11903494_1 Pyridine nucleotide-disulphide oxidoreductase - - - 6.824e-293 923.0
CH2_k127_11903494_2 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 8.248e-257 807.0
CH2_k127_11903494_3 PFAM Thiamine pyrophosphate K00170,K18356 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 520.0
CH2_k127_11903494_4 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000008676 129.0
CH2_k127_11952784_0 Tripartite tricarboxylate transporter TctA family K07793 - - 3.345e-270 837.0
CH2_k127_11952784_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 292.0
CH2_k127_11952784_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000001532 226.0
CH2_k127_11952784_3 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000000000001813 189.0
CH2_k127_11990383_0 Aminotransferase K14261 - - 4.421e-214 670.0
CH2_k127_11990383_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 596.0
CH2_k127_11990383_10 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 307.0
CH2_k127_11990383_11 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 312.0
CH2_k127_11990383_12 Lysin motif K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001063 286.0
CH2_k127_11990383_13 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000001412 252.0
CH2_k127_11990383_14 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000002306 199.0
CH2_k127_11990383_15 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000001123 131.0
CH2_k127_11990383_16 Lytic murein transglycosylase K08305 - - 0.00000002403 55.0
CH2_k127_11990383_17 plastoquinol--plastocyanin reductase activity - - - 0.0004026 45.0
CH2_k127_11990383_2 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 456.0
CH2_k127_11990383_3 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 454.0
CH2_k127_11990383_4 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 401.0
CH2_k127_11990383_5 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 391.0
CH2_k127_11990383_6 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 368.0
CH2_k127_11990383_7 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 357.0
CH2_k127_11990383_8 RNA polymerase sigma factor K03087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 357.0
CH2_k127_11990383_9 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 353.0
CH2_k127_12148425_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.994e-238 747.0
CH2_k127_12148425_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 337.0
CH2_k127_12148425_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000003638 234.0
CH2_k127_12169880_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1328.0
CH2_k127_12169880_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.826e-196 618.0
CH2_k127_12169880_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 529.0
CH2_k127_12169880_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 456.0
CH2_k127_12169880_4 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 421.0
CH2_k127_12169880_5 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 309.0
CH2_k127_12169880_6 Cytidylate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000375 260.0
CH2_k127_12169880_7 Belongs to the ompA family K03286 - - 0.00004094 54.0
CH2_k127_12173313_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.277e-286 902.0
CH2_k127_12173313_1 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 587.0
CH2_k127_12173313_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 400.0
CH2_k127_12173313_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 319.0
CH2_k127_12173313_4 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 311.0
CH2_k127_12173313_5 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 308.0
CH2_k127_12173313_6 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 293.0
CH2_k127_12173313_7 Glutamine amidotransferase class-I - - - 0.00000000000000000000000000000000000000000000000000000000000001165 224.0
CH2_k127_12173313_8 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000006745 209.0
CH2_k127_12173313_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000001218 88.0
CH2_k127_12178598_0 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 358.0
CH2_k127_12178598_1 Glycosyl transferase family 41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 334.0
CH2_k127_12178598_2 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000000000634 209.0
CH2_k127_12178598_3 ExbD is part of the TonB-dependent transduction complex. The TonB complex uses the proton gradient across the inner bacterial membrane to transport large molecules across the outer bacterial membrane. InterPro Biopolymer transport protein ExbD TolR Pfam Biopolymer transport protein ExbD TolR no signal peptide K03559 - - 0.000000000000000000000000000000000000000000000000002248 188.0
CH2_k127_12178598_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000000000000000000000000003699 122.0
CH2_k127_12179273_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1210.0
CH2_k127_12179273_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 9.242e-306 946.0
CH2_k127_12179273_10 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000002046 271.0
CH2_k127_12179273_11 Thioredoxin-like - - - 0.000000000000000000000000000000001385 136.0
CH2_k127_12179273_12 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000003757 121.0
CH2_k127_12179273_13 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000000000003838 101.0
CH2_k127_12179273_14 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000000179 76.0
CH2_k127_12179273_15 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000753 81.0
CH2_k127_12179273_16 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000246 59.0
CH2_k127_12179273_17 Carbohydrate kinase K18478 - 2.7.1.184 0.000007562 48.0
CH2_k127_12179273_2 Tripartite tricarboxylate transporter TctA family K07793 - - 3.377e-214 676.0
CH2_k127_12179273_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 580.0
CH2_k127_12179273_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 539.0
CH2_k127_12179273_5 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 516.0
CH2_k127_12179273_6 MnmE helical domain K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 471.0
CH2_k127_12179273_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 442.0
CH2_k127_12179273_8 DNA topoisomerase III K03169 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 430.0
CH2_k127_12179273_9 PFAM conserved K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 338.0
CH2_k127_12184713_0 STAS domain K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 451.0
CH2_k127_12184713_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 458.0
CH2_k127_12184713_10 FabA-like domain - - - 0.000000000000000000000002025 118.0
CH2_k127_12184713_2 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 370.0
CH2_k127_12184713_3 KR domain K10780 - 1.3.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 300.0
CH2_k127_12184713_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001512 254.0
CH2_k127_12184713_5 lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000004602 258.0
CH2_k127_12184713_6 ADP-heptose-lipopolysaccharide heptosyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000006391 241.0
CH2_k127_12184713_7 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000817 223.0
CH2_k127_12184713_8 Phosphopantetheine attachment site - - - 0.000000000000000000000000000000000000003042 153.0
CH2_k127_12184713_9 O-Antigen ligase - - - 0.000000000000000000000000004659 125.0
CH2_k127_12191606_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 7.246e-253 791.0
CH2_k127_12191606_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 439.0
CH2_k127_12191606_2 Adenylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 336.0
CH2_k127_12191606_3 Protein of unknown function (DUF3095) - - - 0.0000000000000000000003601 99.0
CH2_k127_12191606_4 Protein of unknown function (DUF3095) - - - 0.000004406 51.0
CH2_k127_12198673_0 FAD dependent oxidoreductase K06954 - - 1.327e-202 642.0
CH2_k127_12198673_1 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 503.0
CH2_k127_12198673_2 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 337.0
CH2_k127_12198673_3 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001866 268.0
CH2_k127_12198673_4 Outer Membrane Lipoprotein K03098 - - 0.000000000000000000000000000000000000004957 147.0
CH2_k127_12206068_0 oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 355.0
CH2_k127_12206068_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000003562 230.0
CH2_k127_12248764_0 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 319.0
CH2_k127_12248764_1 Prokaryotic cytochrome b561 K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001715 271.0
CH2_k127_12248764_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 0.00000000000000000000000000000000000000000008738 160.0
CH2_k127_12248764_3 PFAM cytoplasmic chaperone TorD family protein - - - 0.000000000000000000000000000000000005357 146.0
CH2_k127_12248764_4 Helix-turn-helix K21498 - - 0.00000000000000000000001598 115.0
CH2_k127_12248764_5 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000001655 79.0
CH2_k127_12262055_0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 489.0
CH2_k127_12262055_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009666 479.0
CH2_k127_12262055_2 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 316.0
CH2_k127_12262055_3 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000001759 120.0
CH2_k127_12262055_4 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 - 1.6.5.8 0.0000000000000000002179 93.0
CH2_k127_12263647_0 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005188 269.0
CH2_k127_12263647_1 Vitamin k epoxide reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006738 269.0
CH2_k127_12263647_2 Domain of unknown function (DUF4160) - - - 0.000000000000831 78.0
CH2_k127_12263647_3 Protein of unknown function (DUF2442) - - - 0.0000000002799 64.0
CH2_k127_12277809_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 318.0
CH2_k127_12277809_1 ABC transporter K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009264 309.0
CH2_k127_12277809_2 thiosulfate sulfurtransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001315 274.0
CH2_k127_12277809_3 PIN domain - - - 0.000000000000000000000000000000000002339 141.0
CH2_k127_12301745_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2261.0
CH2_k127_12301745_1 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 2.883e-236 738.0
CH2_k127_12301745_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 623.0
CH2_k127_12301745_3 TIGRFAM arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 579.0
CH2_k127_12301745_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 481.0
CH2_k127_12301745_5 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 318.0
CH2_k127_12374167_0 Signal transduction histidine kinase K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000001069 251.0
CH2_k127_12374167_1 Response regulator receiver K15012 - - 0.000000000000000000000000000000000000000000000000000000002442 209.0
CH2_k127_12374167_2 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0001643 45.0
CH2_k127_12381237_0 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 8.282e-243 755.0
CH2_k127_12381237_1 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 456.0
CH2_k127_12381237_2 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000000000000000000002652 200.0
CH2_k127_12381237_3 - - - - 0.0000000000000000000000000000000000000000000000009236 181.0
CH2_k127_12381237_4 DsrC like protein K11179 - - 0.000000000000000000000000000000000000006345 147.0
CH2_k127_12381237_5 - - - - 0.0000000000000000006304 89.0
CH2_k127_12381237_6 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000006976 79.0
CH2_k127_12381237_7 Cas6 Crispr - - - 0.00000000000001744 81.0
CH2_k127_12381237_8 Cas6 Crispr - - - 0.000001602 51.0
CH2_k127_12446050_0 Protein of unknown function (DUF2817) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 398.0
CH2_k127_12446050_1 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007478 327.0
CH2_k127_12471870_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 430.0
CH2_k127_12471870_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 350.0
CH2_k127_12471870_2 DnaJ homolog subfamily B member K09517 GO:0002682,GO:0002684,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0012505,GO:0016020,GO:0031347,GO:0031349,GO:0031974,GO:0032991,GO:0034663,GO:0035821,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044003,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0045088,GO:0045089,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052033,GO:0052166,GO:0052167,GO:0052169,GO:0052173,GO:0052200,GO:0052255,GO:0052257,GO:0052305,GO:0052306,GO:0052308,GO:0052509,GO:0052510,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0070013,GO:0071944,GO:0075136,GO:0080134 - 0.000179 51.0
CH2_k127_12480199_0 Belongs to the pyruvate kinase family - - - 5.167e-202 638.0
CH2_k127_12480199_1 COG0402 Cytosine deaminase and related metal-dependent hydrolases K01487 - 3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 588.0
CH2_k127_12480199_2 Pfam:DUF989 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 579.0
CH2_k127_12480199_3 Basic membrane lipoprotein K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 537.0
CH2_k127_12480199_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 451.0
CH2_k127_12480199_5 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 379.0
CH2_k127_12573414_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 389.0
CH2_k127_12573414_1 epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000155 227.0
CH2_k127_12573414_2 glycosyl transferase K07011 - - 0.0000000000000000000000000000000000000000000000001163 181.0
CH2_k127_12605829_0 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 5.951e-317 986.0
CH2_k127_12605829_1 transport system, fused permease components - - - 6.142e-293 916.0
CH2_k127_12605829_2 PFAM Glycoside hydrolase 15-related - - - 1.982e-267 836.0
CH2_k127_12605829_3 transport system periplasmic component K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 468.0
CH2_k127_12605829_4 fad dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 466.0
CH2_k127_12605829_5 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000002155 227.0
CH2_k127_12605829_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000003798 70.0
CH2_k127_12605829_7 Domain of unknown function (DUF1850) - - - 0.000000002754 70.0
CH2_k127_12641011_0 tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 9.564e-199 630.0
CH2_k127_12641011_1 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 573.0
CH2_k127_12641011_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 464.0
CH2_k127_12641011_3 Pfam Glycosyl transferase family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 422.0
CH2_k127_12641011_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 410.0
CH2_k127_12641011_5 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 396.0
CH2_k127_12641011_6 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 344.0
CH2_k127_12641011_7 FR47-like protein - - - 0.00000000000000000000000000000000000000008049 156.0
CH2_k127_12641011_8 Small Multidrug Resistance protein - - - 0.0000000000000000000000000000000004624 134.0
CH2_k127_12641192_0 COG1960 Acyl-CoA dehydrogenases K20035 - - 6.799e-211 664.0
CH2_k127_12641192_1 Electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 392.0
CH2_k127_12648677_0 Sulfatase K01130 - 3.1.6.1 0.0 1029.0
CH2_k127_12648677_1 Arylsulfatase K01130 - 3.1.6.1 5.343e-212 669.0
CH2_k127_12648677_2 radical SAM domain protein K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 522.0
CH2_k127_12648677_3 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 448.0
CH2_k127_12648677_4 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 385.0
CH2_k127_12648677_5 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 318.0
CH2_k127_12648677_6 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000000000000000000000000000000861 184.0
CH2_k127_12648677_7 membrane - - - 0.000000000000000001961 92.0
CH2_k127_12648677_8 - - - - 0.00000000000003389 84.0
CH2_k127_12648677_9 PFAM sulfatase K01130 - 3.1.6.1 0.00009713 50.0
CH2_k127_12673724_0 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 317.0
CH2_k127_12673724_1 GntR family - - - 0.0000000000000000000000000000000000000000000000000000000000000001894 233.0
CH2_k127_12673724_2 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.0000000000000000000000002272 108.0
CH2_k127_12674593_0 AMP-binding enzyme C-terminal domain - - - 1.065e-263 823.0
CH2_k127_12674593_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009337 287.0
CH2_k127_12674593_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000004509 261.0
CH2_k127_12674593_3 Isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000000000187 197.0
CH2_k127_12689201_0 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 358.0
CH2_k127_12689201_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 290.0
CH2_k127_12689201_2 Aminoacyl-tRNA editing domain K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000001016 238.0
CH2_k127_12689201_3 Aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000531 128.0
CH2_k127_12689201_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000003406 113.0
CH2_k127_12705681_0 - K07112 - - 0.000000000000000000000000000000000000000000000005509 179.0
CH2_k127_12705681_1 - K07112 - - 0.00000000000000000000000000000000000007199 157.0
CH2_k127_12705681_2 Protein of unknown function (DUF2892) - - - 0.0000000000000000000005214 96.0
CH2_k127_12705681_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000005399 66.0
CH2_k127_12741551_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 5.109e-273 863.0
CH2_k127_12741551_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.672e-238 744.0
CH2_k127_12741551_2 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002501 281.0
CH2_k127_12741551_3 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001298 253.0
CH2_k127_12741551_4 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000006386 225.0
CH2_k127_12741551_5 Fels-1 Prophage Protein-like - - - 0.000000000000005126 84.0
CH2_k127_12741551_6 penicillin-binding protein - - - 0.0003772 48.0
CH2_k127_12745556_0 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000108 254.0
CH2_k127_12745556_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000002621 134.0
CH2_k127_12762299_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 528.0
CH2_k127_12762299_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 289.0
CH2_k127_12762299_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000001187 70.0
CH2_k127_12783601_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000003859 217.0
CH2_k127_12783601_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000306 203.0
CH2_k127_12783601_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000006291 191.0
CH2_k127_12783601_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000002896 156.0
CH2_k127_12784070_0 cytochrome d1 heme K19345 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 516.0
CH2_k127_12784070_1 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 327.0
CH2_k127_12784070_2 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000003751 201.0
CH2_k127_12784070_3 transcriptional regulator AsnC family - - - 0.00000000000000000000000000000000000000000000000004545 181.0
CH2_k127_12790994_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 6.416e-273 856.0
CH2_k127_12790994_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.072e-270 846.0
CH2_k127_12790994_10 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.0000000000000000000000000000000000000004636 155.0
CH2_k127_12790994_11 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000004487 128.0
CH2_k127_12790994_12 Fe-S assembly protein IscX - - - 0.0000000000000000000000000005056 115.0
CH2_k127_12790994_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.266e-215 674.0
CH2_k127_12790994_3 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 598.0
CH2_k127_12790994_4 serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 354.0
CH2_k127_12790994_5 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001685 279.0
CH2_k127_12790994_6 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000001546 243.0
CH2_k127_12790994_7 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000001171 210.0
CH2_k127_12790994_8 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000004131 186.0
CH2_k127_12790994_9 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000004859 186.0
CH2_k127_12829232_0 5-oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 0.0 1682.0
CH2_k127_12853291_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 520.0
CH2_k127_12853291_1 4Fe-4S binding domain K18362 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 361.0
CH2_k127_12853291_2 DMSO reductase anchor subunit (DmsC) - - - 0.000000000000000000000000000000000000000000000000000000001277 212.0
CH2_k127_128645_0 Isocitrate lyase K01637 - 4.1.3.1 1.75e-203 641.0
CH2_k127_128645_1 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 559.0
CH2_k127_128645_2 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000000000000009674 214.0
CH2_k127_128645_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000364 114.0
CH2_k127_12949714_0 Magnesium transport protein CorA K03284 - - 0.000000000000000000000000000000000000000000000000004738 194.0
CH2_k127_12949714_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000107 97.0
CH2_k127_12950220_0 carboxylase K01969 - 6.4.1.4 1.426e-284 881.0
CH2_k127_12950220_1 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 8.924e-246 777.0
CH2_k127_12950220_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 457.0
CH2_k127_12950220_3 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 402.0
CH2_k127_12950220_4 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 331.0
CH2_k127_12950220_5 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 296.0
CH2_k127_12950220_6 Enoyl-CoA hydratase/isomerase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001644 298.0
CH2_k127_12950220_7 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000008163 223.0
CH2_k127_12950220_8 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000007724 212.0
CH2_k127_12950220_9 DSBA-like thioredoxin domain - - - 0.000000000000008823 74.0
CH2_k127_12969740_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 5.67e-260 809.0
CH2_k127_12969740_1 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000005575 192.0
CH2_k127_12984690_0 BNR repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 384.0
CH2_k127_12984690_1 Belongs to the universal stress protein A family - - - 0.00000000000000000000000000000000000000000000000001622 190.0
CH2_k127_12984690_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.000000000000000000000000000000001096 133.0
CH2_k127_12984690_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000001254 120.0
CH2_k127_12984690_4 HNH endonuclease - - - 0.00000000000000006554 87.0
CH2_k127_12984690_5 - - - - 0.00009039 52.0
CH2_k127_12999755_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.032e-309 971.0
CH2_k127_12999755_1 Aromatic amino acid lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 623.0
CH2_k127_12999755_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 313.0
CH2_k127_12999755_3 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000003894 111.0
CH2_k127_136631_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.052e-211 660.0
CH2_k127_136631_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000008685 226.0
CH2_k127_1434448_0 Aminotransferase class I and II K09758 - 4.1.1.12 9.509e-260 810.0
CH2_k127_1434448_1 Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000527 205.0
CH2_k127_1434448_2 Predicted Permease Membrane Region K07085 - - 0.0000000001891 61.0
CH2_k127_1441585_0 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005914 327.0
CH2_k127_1441585_2 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.00000000000000000000000000000000000000000000000000000007649 202.0
CH2_k127_1480901_0 PFAM ATP-binding region ATPase domain protein K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 393.0
CH2_k127_1480901_1 PFAM Response regulator receiver domain K02483,K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 290.0
CH2_k127_1480901_2 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000001978 230.0
CH2_k127_1480901_3 HlyD family secretion protein K02005 - - 0.00000000000000533 76.0
CH2_k127_1480901_4 Dihaem cytochrome c - - - 0.000000006356 57.0
CH2_k127_1490709_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1106.0
CH2_k127_1497935_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 3.864e-217 692.0
CH2_k127_1497935_1 HD domain K13815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 371.0
CH2_k127_1497935_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000001418 175.0
CH2_k127_1497935_3 PFAM regulatory protein, MerR - - - 0.000000000000000000000000000000000000000000009446 171.0
CH2_k127_1497935_4 Belongs to the 'phage' integrase family - - - 0.000008618 52.0
CH2_k127_1525487_0 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 1.484e-209 659.0
CH2_k127_1525487_1 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000002629 181.0
CH2_k127_1527701_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1470.0
CH2_k127_1527701_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 5.607e-207 656.0
CH2_k127_1527701_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 538.0
CH2_k127_1527701_3 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 387.0
CH2_k127_1527701_4 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001972 273.0
CH2_k127_1527701_5 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000000000000000000000005302 132.0
CH2_k127_1527701_6 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000000000000000000000007831 134.0
CH2_k127_1592478_0 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 392.0
CH2_k127_1592478_1 Bacterial-like globin K06886 - - 0.00000000000000000000004124 101.0
CH2_k127_1599073_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1392.0
CH2_k127_1599073_1 Oxidative deamination of D-amino acids K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 511.0
CH2_k127_1599073_2 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 499.0
CH2_k127_1599073_3 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007975 437.0
CH2_k127_1599073_4 Aminotransferase class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 366.0
CH2_k127_1599073_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.00000000000000000000000000000000000000000003924 168.0
CH2_k127_1609739_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004096 267.0
CH2_k127_161683_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 414.0
CH2_k127_161683_1 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 402.0
CH2_k127_1619402_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.24e-264 827.0
CH2_k127_1619402_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 584.0
CH2_k127_1619402_2 Acyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000004934 207.0
CH2_k127_1665540_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K22015 - 1.17.1.9,1.17.99.7 0.0 1240.0
CH2_k127_1701389_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1744.0
CH2_k127_1701389_1 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 1.518e-208 667.0
CH2_k127_1701389_2 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 524.0
CH2_k127_1701389_3 Phenylacetic acid degradation protein PaaY K02617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 297.0
CH2_k127_1701389_4 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000002973 254.0
CH2_k127_1701389_5 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.0000000000000000000000000000000000000004439 156.0
CH2_k127_17990_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 1.686e-230 739.0
CH2_k127_17990_1 sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 500.0
CH2_k127_17990_2 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 351.0
CH2_k127_17990_3 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 307.0
CH2_k127_17990_4 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000002834 207.0
CH2_k127_17990_5 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000002625 144.0
CH2_k127_1810100_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 425.0
CH2_k127_1810100_1 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 320.0
CH2_k127_1810100_2 Haem-degrading - - - 0.0000000000000000000000000000000000000001172 158.0
CH2_k127_1874050_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 1.161e-314 969.0
CH2_k127_1874050_1 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848,K20906 - 5.4.99.2,5.4.99.64 3.024e-281 885.0
CH2_k127_1874050_10 - - - - 0.000000000000000000000002006 113.0
CH2_k127_1874050_11 Protein of unknown function (DUF3106) - - - 0.000000000000000000000003968 113.0
CH2_k127_1874050_12 PFAM RDD domain containing protein - - - 0.000000000000000000004069 105.0
CH2_k127_1874050_13 Protein of unknown function (DUF3619) - - - 0.000000002604 67.0
CH2_k127_1874050_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 3.729e-240 750.0
CH2_k127_1874050_3 Thioredoxin-like K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 388.0
CH2_k127_1874050_4 ArgK protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 361.0
CH2_k127_1874050_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002504 277.0
CH2_k127_1874050_6 RNA polymerase K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000009738 250.0
CH2_k127_1874050_7 COG2185 Methylmalonyl-CoA mutase, C-terminal domain subunit (cobalamin-binding) K01849,K20907 - 5.4.99.2,5.4.99.64 0.0000000000000000000000000000000000000000000000000000000002334 208.0
CH2_k127_1874050_8 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000855 191.0
CH2_k127_1874050_9 Acetolactate synthase small K01653 - 2.2.1.6 0.00000000000000000000000000006955 119.0
CH2_k127_1885681_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 532.0
CH2_k127_1885681_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 404.0
CH2_k127_1885681_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000004451 181.0
CH2_k127_1885681_3 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000004391 129.0
CH2_k127_1885681_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000002257 102.0
CH2_k127_1889584_0 AcyL-CoA dehydrogenase K06445 - - 0.0 1083.0
CH2_k127_1889584_1 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 2.468e-249 786.0
CH2_k127_1889584_10 Thioesterase superfamily protein K10806 - - 0.000000000000000000000000000000000000000000004862 179.0
CH2_k127_1889584_11 - - - - 0.00000000000000000000000006594 114.0
CH2_k127_1889584_12 Chalcone isomerase-like - - - 0.00000000000306 72.0
CH2_k127_1889584_13 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000006954 67.0
CH2_k127_1889584_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 3.723e-248 776.0
CH2_k127_1889584_3 Belongs to the thiolase family K00626 - 2.3.1.9 7.129e-222 694.0
CH2_k127_1889584_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 436.0
CH2_k127_1889584_5 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 310.0
CH2_k127_1889584_6 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 326.0
CH2_k127_1889584_7 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008821 259.0
CH2_k127_1889584_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000001929 243.0
CH2_k127_1889584_9 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000586 242.0
CH2_k127_1891699_0 Required for chromosome condensation and partitioning K03529 - - 2.764e-285 921.0
CH2_k127_1891699_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 4.103e-274 859.0
CH2_k127_1891699_10 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 409.0
CH2_k127_1891699_11 Transcriptional regulator, LysR family K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 350.0
CH2_k127_1891699_12 haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000001486 209.0
CH2_k127_1891699_13 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000000000000000000000000003632 196.0
CH2_k127_1891699_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 1.109e-273 850.0
CH2_k127_1891699_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 1.715e-204 641.0
CH2_k127_1891699_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.72e-196 621.0
CH2_k127_1891699_5 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004152 505.0
CH2_k127_1891699_6 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 495.0
CH2_k127_1891699_7 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 455.0
CH2_k127_1891699_8 N-terminal TM domain of oligopeptide transport permease C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 441.0
CH2_k127_1891699_9 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 433.0
CH2_k127_1895811_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 1.121e-232 739.0
CH2_k127_1895811_1 FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 392.0
CH2_k127_1895811_2 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 331.0
CH2_k127_1895811_3 PFAM Dehydrogenase, E1 component K00166 - 1.2.4.4 0.0000000000001667 78.0
CH2_k127_1895811_4 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000002203 57.0
CH2_k127_1908513_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 562.0
CH2_k127_1908513_1 Glycoprotease family K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 - 0.00000000000000000000000000000000000000009946 163.0
CH2_k127_1908513_2 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.00000000002146 64.0
CH2_k127_1913194_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 8.809e-231 722.0
CH2_k127_1913194_1 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000005079 225.0
CH2_k127_1913194_2 response regulator receiver K02658 - - 0.0000000000000000001514 96.0
CH2_k127_1916511_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.078e-205 648.0
CH2_k127_1916511_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 362.0
CH2_k127_1916511_2 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 319.0
CH2_k127_1916511_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000004458 207.0
CH2_k127_1916511_4 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000001343 183.0
CH2_k127_1916511_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000005668 61.0
CH2_k127_1917089_0 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000489 226.0
CH2_k127_1917089_1 Aminomethyltransferase folate-binding domain K06980 - - 0.00000000000000000000000000000000000000000000000000000000004499 214.0
CH2_k127_1917089_2 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000009366 51.0
CH2_k127_1934525_0 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 427.0
CH2_k127_1934525_1 AMP-dependent synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003405 284.0
CH2_k127_1934525_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002842 254.0
CH2_k127_1934525_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000002166 124.0
CH2_k127_1935837_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1552.0
CH2_k127_1935837_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 453.0
CH2_k127_1935837_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004021 284.0
CH2_k127_1935837_3 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000001079 216.0
CH2_k127_1935837_4 ABC transporter substrate binding protein - - - 0.000000000002084 67.0
CH2_k127_1960828_0 protein conserved in bacteria K09989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 531.0
CH2_k127_1960828_1 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 491.0
CH2_k127_1960828_2 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 485.0
CH2_k127_1960828_3 Fructosamine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 316.0
CH2_k127_1960828_4 Acetyltransferase (GNAT) domain K22479 - - 0.0000000000000000000000000000000000000000000000000000000000000162 221.0
CH2_k127_1960828_5 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000000000000002929 167.0
CH2_k127_196980_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 568.0
CH2_k127_196980_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000006688 252.0
CH2_k127_196980_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00180 - 1.2.7.8 0.00000000000000003644 83.0
CH2_k127_2019822_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0 1061.0
CH2_k127_2019822_1 AMP-binding enzyme C-terminal domain - - - 4.954e-229 720.0
CH2_k127_2019822_2 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 467.0
CH2_k127_2019822_3 FAD binding domain K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 427.0
CH2_k127_2019822_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003478 244.0
CH2_k127_2019822_5 - - - - 0.00000000000000000004006 101.0
CH2_k127_2019822_6 - - - - 0.000000000000004778 85.0
CH2_k127_2019822_7 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000001607 74.0
CH2_k127_2090425_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1036.0
CH2_k127_2090425_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0 1021.0
CH2_k127_2090425_2 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00122 - 1.17.1.9 3.24e-251 791.0
CH2_k127_2090425_3 Involved in the catabolism of oxalate and in the adapatation to low pH via the induction of the oxalate-dependent acid tolerance response (ATR). Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate K07749 - 2.8.3.16 2.528e-249 772.0
CH2_k127_2090425_4 CoA-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 437.0
CH2_k127_2090425_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 338.0
CH2_k127_2094686_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 405.0
CH2_k127_2094686_1 Phosphopantetheine attachment site - - - 0.0000000000000000002049 92.0
CH2_k127_2094686_2 S-acyltransferase activity K00627 - 2.3.1.12 0.00000000001923 64.0
CH2_k127_2094686_3 Protein of unknown function (DUF2934) - - - 0.0000002415 57.0
CH2_k127_2184559_0 Belongs to the peptidase S11 family K07262 GO:0000003,GO:0000270,GO:0000910,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006022,GO:0006508,GO:0006807,GO:0007049,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016043,GO:0016787,GO:0019538,GO:0019954,GO:0022402,GO:0022414,GO:0030203,GO:0032505,GO:0042221,GO:0042493,GO:0042597,GO:0043093,GO:0043170,GO:0044238,GO:0044464,GO:0045229,GO:0050896,GO:0051301,GO:0070011,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 - 0.000000000000000000000000000000000000000004348 165.0
CH2_k127_2184559_1 Protein of unknown function (DUF3617) - - - 0.0000000000000000000000000001198 127.0
CH2_k127_2203514_0 peptidase m48, ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 324.0
CH2_k127_2203514_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000004424 204.0
CH2_k127_228740_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000004193 244.0
CH2_k127_228740_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000002475 232.0
CH2_k127_228740_2 Cytochrome b561 K12262 - - 0.000000000000000000000000000000000000000000000000000000000000001103 228.0
CH2_k127_228740_3 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000006015 163.0
CH2_k127_2290045_0 Acyl-CoA dehydrogenase, N-terminal domain K00249 - 1.3.8.7 4.658e-206 648.0
CH2_k127_2290045_1 Belongs to the long-chain O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 419.0
CH2_k127_2290045_2 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 337.0
CH2_k127_229869_0 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 366.0
CH2_k127_229869_1 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000005911 228.0
CH2_k127_2331799_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 8.598e-261 809.0
CH2_k127_2331799_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 378.0
CH2_k127_2331799_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000001471 186.0
CH2_k127_2331799_3 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase - - - 0.0006363 46.0
CH2_k127_2346533_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.146e-203 646.0
CH2_k127_2346533_1 ATP-independent chaperone mediated protein folding K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 514.0
CH2_k127_2346533_10 Phasin protein - - - 0.000000000000000000000000000001113 131.0
CH2_k127_2346533_11 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000002742 102.0
CH2_k127_2346533_12 S-layer homology domain - - - 0.00000000007715 75.0
CH2_k127_2346533_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007203 431.0
CH2_k127_2346533_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 411.0
CH2_k127_2346533_4 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 380.0
CH2_k127_2346533_5 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 306.0
CH2_k127_2346533_6 Aldose 1-epimerase K01785 - 5.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 287.0
CH2_k127_2346533_7 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005415 294.0
CH2_k127_2346533_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007844 263.0
CH2_k127_2346533_9 synthesis repressor, PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000212 241.0
CH2_k127_2357554_0 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001376 293.0
CH2_k127_2357554_1 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006113 275.0
CH2_k127_2357554_2 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000009957 263.0
CH2_k127_2357554_3 Alpha beta hydrolase K14731 - 3.1.1.83 0.00001286 48.0
CH2_k127_2358486_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 1.228e-208 659.0
CH2_k127_2358486_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 460.0
CH2_k127_2358486_2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - - 0.000000000000000000000000000000000002957 140.0
CH2_k127_2364641_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138,K18303 - - 0.0 1193.0
CH2_k127_2364641_1 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 1.411e-212 666.0
CH2_k127_2364641_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000115 166.0
CH2_k127_2364641_11 transcriptional regulator - - - 0.00000000000000000000000000000000000006379 151.0
CH2_k127_2364641_12 GYD domain - - - 0.0000000000000000000000000006425 118.0
CH2_k127_2364641_2 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 564.0
CH2_k127_2364641_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 514.0
CH2_k127_2364641_4 fumarylacetoacetate hydrolase K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 292.0
CH2_k127_2364641_5 Maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008218 273.0
CH2_k127_2364641_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001571 272.0
CH2_k127_2364641_7 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000001691 269.0
CH2_k127_2364641_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000008695 176.0
CH2_k127_2364641_9 Bacterial extracellular solute-binding protein K02012,K11081 - - 0.00000000000000000000000000000000000000000000001943 176.0
CH2_k127_2375355_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 601.0
CH2_k127_2375355_1 Carbon-nitrogen hydrolase K01501,K01502 GO:0000257,GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0016787,GO:0016810,GO:0016815,GO:0018762,GO:0022607,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0065003,GO:0071840 3.5.5.1,3.5.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 435.0
CH2_k127_2375355_10 - - - - 0.0000000007448 61.0
CH2_k127_2375355_11 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000003394 49.0
CH2_k127_2375355_2 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 300.0
CH2_k127_2375355_3 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006828 266.0
CH2_k127_2375355_4 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000004882 213.0
CH2_k127_2375355_5 HNH nucleases - - - 0.0000000000000000000000000000000000000000000007092 172.0
CH2_k127_2375355_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000000000001671 168.0
CH2_k127_2375355_7 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000001004 158.0
CH2_k127_2375355_8 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000527 143.0
CH2_k127_2375355_9 Cmp dcmp deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000141 110.0
CH2_k127_238302_0 Belongs to the TPP enzyme family K03336 - 3.7.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009606 553.0
CH2_k127_238302_1 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 432.0
CH2_k127_238302_2 KduI/IolB family K03337 - 5.3.1.30 0.000000000000000000009412 102.0
CH2_k127_2393559_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 507.0
CH2_k127_2393559_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 378.0
CH2_k127_2393559_2 peptidase, S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 355.0
CH2_k127_2393559_3 HAD-superfamily hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000001971 231.0
CH2_k127_2393559_4 drug resistance transporter, Bcr CflA subfamily K07552 - - 0.0000000000000000000000000000000000000000000000713 174.0
CH2_k127_2393559_5 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000005918 146.0
CH2_k127_2393559_6 rieske 2fe-2s - - - 0.000000000000000000000000000008712 131.0
CH2_k127_2396233_0 TIGRFAM malate synthase A K01638 - 2.3.3.9 9.688e-261 812.0
CH2_k127_2396233_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.47e-245 769.0
CH2_k127_2396233_2 Cysteine-rich domain - - - 6.802e-218 684.0
CH2_k127_2396233_3 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 349.0
CH2_k127_2396233_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 323.0
CH2_k127_2396233_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 302.0
CH2_k127_2396233_6 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001041 251.0
CH2_k127_2396233_7 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000000000000000000004277 155.0
CH2_k127_2396233_8 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000001782 118.0
CH2_k127_2396233_9 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000001624 109.0
CH2_k127_2407866_0 ABC-type dipeptide transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 337.0
CH2_k127_2407866_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 301.0
CH2_k127_2407866_2 aminotransferase K00821,K00840 GO:0003674,GO:0003824,GO:0003992,GO:0004069,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006553,GO:0006591,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009016,GO:0009058,GO:0009064,GO:0009066,GO:0009067,GO:0009084,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0036094,GO:0042450,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.11,2.6.1.17,2.6.1.81 0.000000000000000000000000000000000000000000000000000000001592 204.0
CH2_k127_2488931_0 Histidine kinase-like ATPases - - - 4.814e-256 814.0
CH2_k127_2601520_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 398.0
CH2_k127_2601520_1 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 318.0
CH2_k127_2601520_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003136 288.0
CH2_k127_2601520_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000144 203.0
CH2_k127_2608680_0 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 302.0
CH2_k127_2608680_1 TIGRFAM yecA family protein K07039 - - 0.0000000000000000000000000000000052 141.0
CH2_k127_2795389_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 8.887e-197 623.0
CH2_k127_2795389_1 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 422.0
CH2_k127_2795389_10 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000345 202.0
CH2_k127_2795389_2 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 361.0
CH2_k127_2795389_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 339.0
CH2_k127_2795389_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 310.0
CH2_k127_2795389_5 Major Facilitator Superfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001192 275.0
CH2_k127_2795389_6 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007172 260.0
CH2_k127_2795389_7 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002753 252.0
CH2_k127_2795389_8 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000004877 255.0
CH2_k127_2795389_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000001869 237.0
CH2_k127_2815072_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 572.0
CH2_k127_2815072_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087,K03520,K04108 - 1.17.1.4,1.2.5.3,1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 284.0
CH2_k127_2815072_2 KR domain K00059 - 1.1.1.100 0.0000000007431 61.0
CH2_k127_2870843_0 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002056 265.0
CH2_k127_2870843_1 Arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000001132 214.0
CH2_k127_2871627_0 Helicase K03657 - 3.6.4.12 2.004e-303 948.0
CH2_k127_2871627_1 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 548.0
CH2_k127_2871627_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 342.0
CH2_k127_2871627_3 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 328.0
CH2_k127_2871627_4 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000008595 216.0
CH2_k127_2871627_5 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000517 109.0
CH2_k127_2871627_6 Protein of unknown function (DUF2782) - - - 0.0000000000000000000001907 101.0
CH2_k127_2871627_7 - - - - 0.000000000002169 78.0
CH2_k127_2876973_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 1.358e-304 958.0
CH2_k127_2876973_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 547.0
CH2_k127_2876973_10 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004721 277.0
CH2_k127_2876973_11 Disulfide bond isomerase protein N-terminus K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000003777 251.0
CH2_k127_2876973_12 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000001191 233.0
CH2_k127_2876973_13 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000003878 229.0
CH2_k127_2876973_14 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.00000000000000000000000000000000000000000000000000006434 192.0
CH2_k127_2876973_15 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001781 168.0
CH2_k127_2876973_16 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000002192 167.0
CH2_k127_2876973_17 Pfam Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000004081 160.0
CH2_k127_2876973_18 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.00000000000000000000000000000000000001378 147.0
CH2_k127_2876973_19 TonB C terminal K03646 - - 0.000000000000000000000000000000000001431 151.0
CH2_k127_2876973_2 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 509.0
CH2_k127_2876973_20 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000006431 132.0
CH2_k127_2876973_21 - - - - 0.0000008346 62.0
CH2_k127_2876973_22 - - - - 0.00008145 53.0
CH2_k127_2876973_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 475.0
CH2_k127_2876973_4 tRNA wobble cytosine modification - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 464.0
CH2_k127_2876973_5 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 390.0
CH2_k127_2876973_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 383.0
CH2_k127_2876973_7 P-loop ATPase protein family K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 334.0
CH2_k127_2876973_8 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008998 286.0
CH2_k127_2876973_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002259 274.0
CH2_k127_2898579_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 3.223e-220 717.0
CH2_k127_2898579_1 Protein involved in transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 545.0
CH2_k127_2898579_10 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000001495 225.0
CH2_k127_2898579_11 PFAM globin K06886 - - 0.00000000000000000000000000000000000000000000000000396 186.0
CH2_k127_2898579_12 TPM domain K08988 - - 0.00000000000000000000001025 102.0
CH2_k127_2898579_13 Psort location CytoplasmicMembrane, score K02237 - - 0.00000000000000000001446 97.0
CH2_k127_2898579_2 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 491.0
CH2_k127_2898579_3 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 482.0
CH2_k127_2898579_4 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 401.0
CH2_k127_2898579_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 403.0
CH2_k127_2898579_6 aminotransferase class V K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 400.0
CH2_k127_2898579_7 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 396.0
CH2_k127_2898579_8 3'-5' exonuclease K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 354.0
CH2_k127_2898579_9 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 291.0
CH2_k127_2909581_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.189e-265 850.0
CH2_k127_2909581_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.684e-222 704.0
CH2_k127_2909581_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000001597 183.0
CH2_k127_2909581_3 PFAM GGDEF domain containing protein K21019 - 2.7.7.65 0.00000000000000001331 97.0
CH2_k127_2928981_0 phenylacetic acid degradation protein paaN - - - 1.125e-239 752.0
CH2_k127_2928981_1 Oxidoreductase FAD-binding domain K02613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 487.0
CH2_k127_2928981_2 Pfam:DUF59 K02612 - - 0.0000000000000000000000000000000000000000000000000000000007302 206.0
CH2_k127_2935932_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1172.0
CH2_k127_2935932_1 TIGRFAM acyltransferase, WS DGAT MGAT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 567.0
CH2_k127_2935932_2 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 430.0
CH2_k127_2935932_3 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 350.0
CH2_k127_2935932_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 296.0
CH2_k127_2935932_5 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005233 243.0
CH2_k127_2935932_6 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000004124 237.0
CH2_k127_2935932_7 PGAP1-like protein - - - 0.0000000000000000000000000108 124.0
CH2_k127_2935932_8 Rhodanese domain protein - - - 0.0000000000000000000000005194 117.0
CH2_k127_2937101_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 559.0
CH2_k127_2937101_1 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000004736 181.0
CH2_k127_29413_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1233.0
CH2_k127_2982275_0 Protein of unknown function (DUF3305) - - - 0.0000000000000000000000000000000003774 139.0
CH2_k127_2982275_1 Protein of unknown function (DUF3306) - - - 0.0000000000000000000000000007943 123.0
CH2_k127_2982275_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000001591 110.0
CH2_k127_3008281_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 3.23e-306 949.0
CH2_k127_3008281_1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 340.0
CH2_k127_3008281_2 pfkB family carbohydrate kinase K00852,K18478 - 2.7.1.15,2.7.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000000004525 262.0
CH2_k127_3008281_3 rRNA small subunit methyltransferase G K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000005559 216.0
CH2_k127_3008281_4 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000007701 141.0
CH2_k127_3038881_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 319.0
CH2_k127_3038881_1 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 313.0
CH2_k127_3038881_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000001919 241.0
CH2_k127_3038881_3 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000004729 204.0
CH2_k127_3038881_4 rRNA binding K00185,K02967 - - 0.0000000000000000008653 89.0
CH2_k127_3069464_0 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000004626 239.0
CH2_k127_3069464_1 transcriptional regulator K03892 - - 0.00000000000002618 78.0
CH2_k127_3069464_2 alcohol dehydrogenase K14629 - - 0.0000001646 54.0
CH2_k127_30714_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 585.0
CH2_k127_30714_1 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 481.0
CH2_k127_30714_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 456.0
CH2_k127_30714_3 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 430.0
CH2_k127_30714_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003842 272.0
CH2_k127_30714_5 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000004691 146.0
CH2_k127_31922_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 512.0
CH2_k127_31922_1 Biotin and Thiamin Synthesis associated domain K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 479.0
CH2_k127_31922_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 413.0
CH2_k127_31922_3 Psort location Cytoplasmic, score 8.96 K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 315.0
CH2_k127_31922_4 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000001741 204.0
CH2_k127_31922_5 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000009142 186.0
CH2_k127_31922_6 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000005356 171.0
CH2_k127_31922_7 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000007728 149.0
CH2_k127_31922_8 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000003465 144.0
CH2_k127_31922_9 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000999 133.0
CH2_k127_3244863_0 Dehydrogenase K00382 - 1.8.1.4 2.712e-279 869.0
CH2_k127_3244863_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000006892 220.0
CH2_k127_3244863_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000004156 196.0
CH2_k127_3244863_3 - - - - 0.0000000000000000000000000000000000000000000006867 174.0
CH2_k127_3244863_5 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000005091 65.0
CH2_k127_3246947_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 526.0
CH2_k127_3246947_1 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 386.0
CH2_k127_3293486_0 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 455.0
CH2_k127_3293486_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000006391 194.0
CH2_k127_3293486_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000004081 194.0
CH2_k127_3293486_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000006925 168.0
CH2_k127_3293486_4 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000001581 94.0
CH2_k127_3293486_5 Protein of unknown function (DUF3604) - - - 0.00000000003237 66.0
CH2_k127_3299816_0 CoA binding domain - - - 7.331e-260 804.0
CH2_k127_3299816_1 AMP-binding enzyme - - - 0.0009923 43.0
CH2_k127_3304518_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 438.0
CH2_k127_3304518_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 364.0
CH2_k127_3322486_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 4.651e-227 724.0
CH2_k127_3322486_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 556.0
CH2_k127_3322486_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 451.0
CH2_k127_3322486_3 - - - - 0.000000000000000000000000000000000000008866 158.0
CH2_k127_3322486_4 - - - - 0.0000000000000000000002305 105.0
CH2_k127_3322486_5 Belongs to the V-ATPase proteolipid subunit family K02124 - - 0.00000000000000000008996 105.0
CH2_k127_3322486_6 ATP synthase (F/14-kDa) subunit - - - 0.00000000007516 71.0
CH2_k127_3334686_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 6.278e-285 891.0
CH2_k127_3334686_1 Ammonium Transporter Family K03320,K06580 - - 1.601e-221 692.0
CH2_k127_3334686_2 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 524.0
CH2_k127_3334686_3 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 422.0
CH2_k127_3334686_4 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 300.0
CH2_k127_3334686_5 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 297.0
CH2_k127_3334686_6 Guanylate kinase homologues. K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000002952 246.0
CH2_k127_3334686_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000006021 111.0
CH2_k127_33462_0 Hsp90 protein K04079 - - 0.0 1026.0
CH2_k127_33462_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 389.0
CH2_k127_33462_2 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005005 276.0
CH2_k127_33462_3 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009746 261.0
CH2_k127_33462_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000000002106 176.0
CH2_k127_3360536_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 350.0
CH2_k127_3360536_1 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000001236 158.0
CH2_k127_3360536_2 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000001527 128.0
CH2_k127_3374544_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 8.11e-251 788.0
CH2_k127_3377620_0 mandelate racemase muconate lactonizing K01706 - 4.2.1.40 3.986e-199 628.0
CH2_k127_3377620_1 Alcohol dehydrogenase GroES-like domain K00098 - 1.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 433.0
CH2_k127_3377620_2 Short-chain dehydrogenase reductase sdr K18335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 334.0
CH2_k127_3377620_3 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005248 244.0
CH2_k127_3377620_4 Regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000001953 242.0
CH2_k127_3377620_5 Transporter K11688,K21395 - - 0.000000000000000000000000000000000000000000000001815 179.0
CH2_k127_3380815_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 533.0
CH2_k127_3380815_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 505.0
CH2_k127_3380815_2 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 368.0
CH2_k127_3380815_3 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000131 164.0
CH2_k127_3380815_4 PFAM PsiF repeat protein - - - 0.0000000000000000001274 95.0
CH2_k127_3433880_0 Ftsk_gamma K03466 - - 6.462e-306 955.0
CH2_k127_3433880_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 2.97e-267 851.0
CH2_k127_3433880_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 459.0
CH2_k127_3433880_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 415.0
CH2_k127_3433880_12 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 375.0
CH2_k127_3433880_13 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 364.0
CH2_k127_3433880_14 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 322.0
CH2_k127_3433880_15 abc transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 309.0
CH2_k127_3433880_16 DNA polymerase III tau subunit V interacting with alpha K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 286.0
CH2_k127_3433880_17 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006265 300.0
CH2_k127_3433880_18 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000000000000000000000000000001246 229.0
CH2_k127_3433880_19 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000000000433 229.0
CH2_k127_3433880_2 Protein of unknown function - - - 1.292e-262 877.0
CH2_k127_3433880_20 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000000000000005981 225.0
CH2_k127_3433880_21 Nitrogen regulatory protein P-II K04751 - - 0.0000000000000000000000000000000000000000000000000000000001297 205.0
CH2_k127_3433880_22 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000000003915 205.0
CH2_k127_3433880_23 Smr domain - - - 0.000000000000000000000000000000000001289 155.0
CH2_k127_3433880_24 SnoaL-like domain - - - 0.00000000000000000000000000001665 123.0
CH2_k127_3433880_25 Zinc-finger domain - - - 0.000000000000000001836 95.0
CH2_k127_3433880_3 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 1.2e-236 752.0
CH2_k127_3433880_4 TldD PmbA family protein K03568 - - 3.87e-222 698.0
CH2_k127_3433880_5 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 618.0
CH2_k127_3433880_6 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 601.0
CH2_k127_3433880_7 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 597.0
CH2_k127_3433880_8 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 500.0
CH2_k127_3433880_9 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 494.0
CH2_k127_3449326_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 8.107e-245 766.0
CH2_k127_3449326_1 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007395 369.0
CH2_k127_3449326_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000003125 73.0
CH2_k127_3451615_0 PFAM polysaccharide biosynthesis protein CapD - - - 5.095e-220 704.0
CH2_k127_3451615_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 541.0
CH2_k127_3451615_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 437.0
CH2_k127_3451615_3 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 353.0
CH2_k127_3451615_4 PFAM regulatory protein TetR K05501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001544 250.0
CH2_k127_3451615_5 Glycosyl transferase, family 4 K13007 - - 0.00000000000000000000000000000000000000000000000000000000000003836 228.0
CH2_k127_3456460_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 516.0
CH2_k127_3456460_1 twitching motility protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 458.0
CH2_k127_3456460_2 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 417.0
CH2_k127_3456460_3 Phosphorylase superfamily K00772,K03815 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 319.0
CH2_k127_3456460_4 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 316.0
CH2_k127_3456460_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000002018 53.0
CH2_k127_3462636_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1167.0
CH2_k127_3462636_1 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 1.031e-242 764.0
CH2_k127_3462636_10 Cold shock protein K03704 - - 0.000000000000000000000000000000000005098 136.0
CH2_k127_3462636_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.00000000000000000000000528 103.0
CH2_k127_3462636_12 -acetyltransferase K03828,K17840 - 2.3.1.59 0.000000000000001995 87.0
CH2_k127_3462636_2 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 507.0
CH2_k127_3462636_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 320.0
CH2_k127_3462636_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 307.0
CH2_k127_3462636_5 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 284.0
CH2_k127_3462636_6 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000157 267.0
CH2_k127_3462636_7 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000007985 198.0
CH2_k127_3462636_8 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000008747 154.0
CH2_k127_3462636_9 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000005544 149.0
CH2_k127_3466553_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 4.608e-300 938.0
CH2_k127_3466553_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 502.0
CH2_k127_3466553_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 470.0
CH2_k127_3466553_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 340.0
CH2_k127_3466553_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 312.0
CH2_k127_3466553_5 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003994 270.0
CH2_k127_3466553_6 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000004891 269.0
CH2_k127_3466553_7 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000001699 210.0
CH2_k127_3466553_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000135 205.0
CH2_k127_3466553_9 mRNA catabolic process - - - 0.000000000000000000000001645 116.0
CH2_k127_3552572_0 Fe-S oxidoreductase K21834 - - 2.014e-219 683.0
CH2_k127_3552572_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000008086 236.0
CH2_k127_3574294_0 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 2.497e-198 631.0
CH2_k127_3574294_1 chitin deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 540.0
CH2_k127_3574294_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 321.0
CH2_k127_3574294_3 COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B K13482 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 296.0
CH2_k127_3574294_4 periplasmic protein - - - 0.00000000000000000000000000000000000000000000000000000008982 205.0
CH2_k127_3574294_5 NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000008005 197.0
CH2_k127_3574294_6 - - - - 0.000000000000000000000000000000000000000002001 175.0
CH2_k127_3574294_7 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.0000000000000000000000004477 118.0
CH2_k127_3574294_8 Predicted membrane protein (DUF2069) - - - 0.0000000000000000001185 93.0
CH2_k127_3581628_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 337.0
CH2_k127_3581628_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009249 285.0
CH2_k127_3581628_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006887 252.0
CH2_k127_3581628_3 Protein of unknown function (DUF1778) - - - 0.0000000000000000000000000000000000000000002092 160.0
CH2_k127_3639019_0 Aminotransferase K09758 - 4.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 543.0
CH2_k127_3639019_1 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 488.0
CH2_k127_3691392_0 PFAM aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 459.0
CH2_k127_3691392_1 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 409.0
CH2_k127_3691392_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005574 287.0
CH2_k127_3691392_3 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000003331 235.0
CH2_k127_3691392_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000007336 198.0
CH2_k127_3775583_0 Poly-beta-hydroxybutyrate polymerase N terminal K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 606.0
CH2_k127_3775583_1 - - - - 0.0000003526 53.0
CH2_k127_3798286_0 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 6.748e-234 736.0
CH2_k127_3798286_1 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000002091 153.0
CH2_k127_3798286_2 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000008188 107.0
CH2_k127_3798286_3 Protein of unknown function (DUF2783) - - - 0.000000000000000004745 89.0
CH2_k127_3825575_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.522e-201 634.0
CH2_k127_3825575_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 3.563e-197 622.0
CH2_k127_3825575_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000007103 211.0
CH2_k127_3825575_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000007555 141.0
CH2_k127_3825575_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000101 145.0
CH2_k127_3834808_0 Pyridoxal-phosphate dependent enzyme - - - 1.803e-200 629.0
CH2_k127_3834808_1 Flavocytochrome c sulphide dehydrogenase, flavin-binding K05301,K17218 - 1.8.2.1,1.8.5.4 3.042e-199 628.0
CH2_k127_3834808_10 - - - - 0.00000000000000000000764 99.0
CH2_k127_3834808_11 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000007641 98.0
CH2_k127_3834808_12 Lysin motif - - - 0.000000000000000001782 88.0
CH2_k127_3834808_2 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 515.0
CH2_k127_3834808_3 Virulence factor BrkB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 363.0
CH2_k127_3834808_4 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 362.0
CH2_k127_3834808_5 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 369.0
CH2_k127_3834808_6 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 291.0
CH2_k127_3834808_7 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000003878 237.0
CH2_k127_3834808_8 Cytochrome c, class I - - - 0.000000000000000000000000000005083 122.0
CH2_k127_3834808_9 - - - - 0.00000000000000000000000000003765 121.0
CH2_k127_38490_0 COG2010 Cytochrome c, mono- and diheme variants K15864 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1,1.7.99.1 1.331e-299 936.0
CH2_k127_38490_1 Protein of unknown function (DUF808) K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007943 376.0
CH2_k127_38490_2 cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 291.0
CH2_k127_38490_3 Ethylbenzene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 295.0
CH2_k127_38490_4 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004432 270.0
CH2_k127_38490_5 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000000000003392 114.0
CH2_k127_38490_6 Cytochrome D1 heme domain - - - 0.0000000000000000003369 95.0
CH2_k127_38490_7 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000001644 55.0
CH2_k127_3874908_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 8.394e-273 844.0
CH2_k127_3886377_0 Belongs to the enoyl-CoA hydratase isomerase family K19640 - - 1.045e-217 691.0
CH2_k127_3886377_1 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 365.0
CH2_k127_3886377_2 PFAM cytochrome c, class I K08738 - - 0.0000000000003333 74.0
CH2_k127_3892891_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 520.0
CH2_k127_3892891_1 TIGRFAM histidinol-phosphate phosphatase family protein K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005277 270.0
CH2_k127_3892891_2 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000001933 255.0
CH2_k127_3892891_3 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000001113 178.0
CH2_k127_3892891_4 LysM domain K08307 - - 0.000000000000000000000000000000000001133 148.0
CH2_k127_3892891_5 Belongs to the frataxin family K06202 - - 0.00000000000000000000003389 106.0
CH2_k127_3899329_0 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 368.0
CH2_k127_3899329_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 321.0
CH2_k127_3899329_2 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004583 247.0
CH2_k127_3899329_3 Mammalian cell entry related domain protein K02067,K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000326 254.0
CH2_k127_3899329_4 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000001866 256.0
CH2_k127_3899329_5 ABC-type amino acid transport signal transduction systems periplasmic component domain K10001 GO:0003333,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015740,GO:0015800,GO:0015807,GO:0015813,GO:0015849,GO:0015893,GO:0016595,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070335,GO:0070778,GO:0071702,GO:0071705,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000005113 209.0
CH2_k127_3899329_6 Protein conserved in bacteria K18480 - - 0.0000000000000000007837 101.0
CH2_k127_3899329_7 Glycine zipper 2TM domain - - - 0.00000007454 61.0
CH2_k127_3899604_0 DEAD H associated domain protein K03724 - - 4.678e-210 666.0
CH2_k127_3899604_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 308.0
CH2_k127_3905307_0 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 451.0
CH2_k127_3905307_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 479.0
CH2_k127_3905307_10 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000008544 85.0
CH2_k127_3905307_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 312.0
CH2_k127_3905307_3 KR domain K07535 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 298.0
CH2_k127_3905307_4 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000736 275.0
CH2_k127_3905307_5 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001727 266.0
CH2_k127_3905307_6 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000006438 231.0
CH2_k127_3905307_7 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000006092 127.0
CH2_k127_3905307_8 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000001713 115.0
CH2_k127_3905307_9 AMP-binding enzyme K01895 - 6.2.1.1 0.00000000000000000000006264 104.0
CH2_k127_3909476_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.0 1281.0
CH2_k127_3909476_1 MauM NapG family ferredoxin-type protein K02573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 321.0
CH2_k127_3939079_0 Asparagine synthase, glutamine-hydrolyzing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 556.0
CH2_k127_3939079_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 435.0
CH2_k127_3939079_2 glycosyl transferase K16701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 389.0
CH2_k127_3984685_0 PFAM PHP C-terminal K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 318.0
CH2_k127_3984685_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 302.0
CH2_k127_3984685_2 transcriptional regulator, XRE family - - - 0.0000000000000000000000000000000000000000001054 163.0
CH2_k127_3984685_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000004067 91.0
CH2_k127_4090889_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 563.0
CH2_k127_4090889_1 Modulates RecA activity K03565 - - 0.00003081 55.0
CH2_k127_4090889_2 Bacterial protein of unknown function (DUF882) - - - 0.000455 49.0
CH2_k127_4102972_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1318.0
CH2_k127_4102972_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 485.0
CH2_k127_4102972_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004083 476.0
CH2_k127_4102972_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 448.0
CH2_k127_4102972_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 412.0
CH2_k127_4102972_5 ATPase (AAA K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 372.0
CH2_k127_4102972_6 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 324.0
CH2_k127_4102972_7 Peptidase family M23 K08259 - 3.4.24.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 314.0
CH2_k127_4102972_8 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000002898 195.0
CH2_k127_4102972_9 Protein of unknown function (DUF721) - - - 0.00000003441 62.0
CH2_k127_4122442_0 Protein of unknown function (DUF1631) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 401.0
CH2_k127_4122442_1 Atp-dependent helicase K03578 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000033 242.0
CH2_k127_4122442_2 MaoC like domain - - - 0.000000000000000000000000000000000000000000000003682 177.0
CH2_k127_4122442_3 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000003604 141.0
CH2_k127_413520_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 550.0
CH2_k127_413520_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000008289 255.0
CH2_k127_413520_2 Prolyl oligopeptidase family - - - 0.000000000000000000002938 94.0
CH2_k127_413520_3 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000008784 93.0
CH2_k127_413520_4 KTSC domain - - - 0.00000000000000001377 83.0
CH2_k127_413520_5 Periplasmic Protein - GO:0003674,GO:0004857,GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0016020,GO:0019867,GO:0030234,GO:0030312,GO:0030313,GO:0031975,GO:0043086,GO:0044092,GO:0044462,GO:0044464,GO:0050790,GO:0060241,GO:0065007,GO:0065009,GO:0071944,GO:0098772 - 0.00001034 56.0
CH2_k127_4140684_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 562.0
CH2_k127_4140684_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 549.0
CH2_k127_4140684_10 STAS domain K07122 - - 0.00002441 53.0
CH2_k127_4140684_2 ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 391.0
CH2_k127_4140684_3 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 364.0
CH2_k127_4140684_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 319.0
CH2_k127_4140684_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003032 298.0
CH2_k127_4140684_6 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.000000000000000000000000000000000000000000000000000000000000000003968 231.0
CH2_k127_4140684_7 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000005859 220.0
CH2_k127_4140684_8 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000001053 198.0
CH2_k127_4140684_9 Belongs to the BolA IbaG family - - - 0.0000000000000000000005766 109.0
CH2_k127_4204145_0 Belongs to the TPP enzyme family K03852 - 2.3.3.15 7.34e-260 810.0
CH2_k127_4204145_1 Transglycosylase SLT domain - - - 2.558e-197 646.0
CH2_k127_4204145_2 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 445.0
CH2_k127_4204145_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000009532 224.0
CH2_k127_4204145_4 Cytochrome B561 K12262 - - 0.000000000000000000000000000000000000165 149.0
CH2_k127_4216683_0 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 509.0
CH2_k127_4216683_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000002461 161.0
CH2_k127_4224671_0 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 7.749e-225 715.0
CH2_k127_4224671_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 540.0
CH2_k127_4224671_10 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000000002155 144.0
CH2_k127_4224671_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 412.0
CH2_k127_4224671_3 ABC transport system ATP-binding protein K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 389.0
CH2_k127_4224671_4 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 378.0
CH2_k127_4224671_5 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 365.0
CH2_k127_4224671_6 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.0000000000000000000000000000000000000000000000000002441 189.0
CH2_k127_4224671_7 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.000000000000000000000000000000000000000009503 169.0
CH2_k127_4224671_8 ribosomal subunit interface protein K05808 - - 0.00000000000000000000000000000000000001149 148.0
CH2_k127_4224671_9 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000009322 156.0
CH2_k127_4257430_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 592.0
CH2_k127_4257430_1 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000003449 236.0
CH2_k127_4259884_0 Organic solvent tolerance protein K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 570.0
CH2_k127_4259884_1 Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 438.0
CH2_k127_4259884_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 465.0
CH2_k127_4259884_3 Belongs to the methyltransferase superfamily K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 433.0
CH2_k127_4259884_4 Peptidase family M3 K01414 - 3.4.24.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 361.0
CH2_k127_4259884_5 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001492 273.0
CH2_k127_4259884_6 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000006481 251.0
CH2_k127_4259884_7 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03830 - - 0.0000000000000000003933 94.0
CH2_k127_4259884_8 Protein of unknown function (DUF3460) - - - 0.00000000001984 66.0
CH2_k127_4270499_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.372e-199 632.0
CH2_k127_4270499_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 343.0
CH2_k127_4270499_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 323.0
CH2_k127_4270499_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 311.0
CH2_k127_4270499_4 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001037 285.0
CH2_k127_4270499_5 UPF0761 membrane protein K07058 - - 0.00000000000000000000000000000000000000000000000001168 188.0
CH2_k127_4270499_6 Biopolymer transport protein K03559 - - 0.00000000000000000000000000000000000000005588 155.0
CH2_k127_4299316_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.08e-211 664.0
CH2_k127_4299316_1 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 304.0
CH2_k127_4299316_2 - - - - 0.0002776 49.0
CH2_k127_4300047_0 Protein conserved in bacteria K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 611.0
CH2_k127_4300047_1 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 587.0
CH2_k127_4300047_10 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000002955 91.0
CH2_k127_4300047_2 Protein of unknown function (DUF993) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 538.0
CH2_k127_4300047_3 Putative oxidoreductase C terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 538.0
CH2_k127_4300047_4 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 469.0
CH2_k127_4300047_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000077 454.0
CH2_k127_4300047_6 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 402.0
CH2_k127_4300047_7 4Fe-4S dicluster domain K16887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007952 319.0
CH2_k127_4300047_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000002838 214.0
CH2_k127_4300047_9 Domain of unknown function (DUF4202) - - - 0.000000000000000000000005805 103.0
CH2_k127_4324503_0 Belongs to the peptidase S1C family K04691,K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 418.0
CH2_k127_4324503_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 358.0
CH2_k127_4324503_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 310.0
CH2_k127_4324503_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 315.0
CH2_k127_4324503_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000002052 196.0
CH2_k127_4324503_5 Nucleotide transport and metabolism Carbohydrate transport and metabolism General function prediction only K02503 - - 0.00000000000000000000000000000000000000000000000396 175.0
CH2_k127_4324503_6 Psort location Cytoplasmic, score K01523 - 3.6.1.31 0.00000000000000000000000000000000002467 138.0
CH2_k127_4324503_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000005079 119.0
CH2_k127_4324503_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 - 0.00000000000000000000001186 101.0
CH2_k127_4324503_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000003143 103.0
CH2_k127_4324611_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 9.74e-233 734.0
CH2_k127_4324611_1 general secretion pathway protein D K02453 - - 3.409e-196 636.0
CH2_k127_4324611_10 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000005935 208.0
CH2_k127_4324611_11 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000005494 205.0
CH2_k127_4324611_12 atpase or kinase K06925 - - 0.00000000000000000000000000000000000000000001184 171.0
CH2_k127_4324611_13 transcriptional regulator K07734 - - 0.00000000000000000000000000000000000000000001721 169.0
CH2_k127_4324611_14 PFAM regulatory protein, MerR K22491 - - 0.00000000000000000000000000000000000000000002886 177.0
CH2_k127_4324611_15 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000006386 126.0
CH2_k127_4324611_16 - - - - 0.000000000000000000000000000111 132.0
CH2_k127_4324611_17 - - - - 0.000000000000000000000000008941 123.0
CH2_k127_4324611_18 Psort location CytoplasmicMembrane, score - - - 0.0001268 53.0
CH2_k127_4324611_2 type II secretion system protein E K02454,K02652,K12276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 593.0
CH2_k127_4324611_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 499.0
CH2_k127_4324611_4 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 451.0
CH2_k127_4324611_5 PFAM type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 341.0
CH2_k127_4324611_6 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 334.0
CH2_k127_4324611_7 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 293.0
CH2_k127_4324611_8 PFAM 20S proteasome, A and B subunits K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000003583 250.0
CH2_k127_4324611_9 PFAM Lytic transglycosylase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000005632 231.0
CH2_k127_4326889_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1837.0
CH2_k127_4326889_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 5.818e-271 848.0
CH2_k127_4326889_10 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 421.0
CH2_k127_4326889_11 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 404.0
CH2_k127_4326889_12 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 406.0
CH2_k127_4326889_13 Exonuclease VII, large subunit K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 409.0
CH2_k127_4326889_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 408.0
CH2_k127_4326889_15 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 370.0
CH2_k127_4326889_16 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 318.0
CH2_k127_4326889_17 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 GO:0002252,GO:0002376,GO:0003674,GO:0003824,GO:0006464,GO:0006476,GO:0006807,GO:0006935,GO:0006950,GO:0006952,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018205,GO:0019213,GO:0019538,GO:0033558,GO:0034979,GO:0034983,GO:0035601,GO:0036048,GO:0036049,GO:0036055,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0051607,GO:0051704,GO:0051707,GO:0071704,GO:0098542,GO:0098732,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001652 282.0
CH2_k127_4326889_18 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001839 267.0
CH2_k127_4326889_19 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000009051 248.0
CH2_k127_4326889_2 glutaminyl-tRNA K01886 - 6.1.1.18 1.625e-262 822.0
CH2_k127_4326889_20 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000004623 169.0
CH2_k127_4326889_21 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000000000000003724 162.0
CH2_k127_4326889_22 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000001415 136.0
CH2_k127_4326889_23 SNARE associated Golgi protein K03975 - - 0.00000000000005462 73.0
CH2_k127_4326889_24 UPF0761 membrane protein K07058 - - 0.0000008636 54.0
CH2_k127_4326889_3 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 1.54e-247 779.0
CH2_k127_4326889_4 Sulfatase - - - 4.135e-196 646.0
CH2_k127_4326889_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.724e-194 617.0
CH2_k127_4326889_6 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 571.0
CH2_k127_4326889_7 response regulator K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 567.0
CH2_k127_4326889_8 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 443.0
CH2_k127_4326889_9 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 460.0
CH2_k127_4330661_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 352.0
CH2_k127_4330661_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000002465 263.0
CH2_k127_4330661_2 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000000002807 228.0
CH2_k127_4330661_3 dna polymerase iii K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000004002 239.0
CH2_k127_4330661_4 general secretion pathway protein K K02460 - - 0.00000000000000000000000000000000000000000000000000000002613 213.0
CH2_k127_4330661_5 PFAM Type IV pilus assembly PilZ K02676 - - 0.000000000000000000000000000000002786 130.0
CH2_k127_4330661_6 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0000000000000000000000008869 113.0
CH2_k127_4330661_7 Type II secretion system (T2SS), protein I K02458 - - 0.00000000000000000004722 101.0
CH2_k127_4330661_8 general secretion pathway protein K02457 - - 0.000000000006424 75.0
CH2_k127_4347714_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1073.0
CH2_k127_4347714_1 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 430.0
CH2_k127_4347714_2 bacterial (prokaryotic) histone like domain - - - 0.000000000000000000000000000000004574 133.0
CH2_k127_4347714_3 - - - - 0.00000001552 59.0
CH2_k127_4347714_4 - - - - 0.00000008907 55.0
CH2_k127_4356449_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 4.125e-292 905.0
CH2_k127_4356449_1 O-methyltransferase activity - - - 8.325e-208 666.0
CH2_k127_4356449_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 380.0
CH2_k127_4356449_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 291.0
CH2_k127_4356449_4 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000001946 196.0
CH2_k127_4361431_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 513.0
CH2_k127_4361431_1 TilS substrate binding domain K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 309.0
CH2_k127_4361431_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000004759 182.0
CH2_k127_4361431_3 CoA-transferase family III K18289 - 2.8.3.22 0.0000000000000000004349 89.0
CH2_k127_4362136_0 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 348.0
CH2_k127_4362136_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006526 244.0
CH2_k127_4362136_2 ABC transporter K01995 - - 0.000000000000000000000000000000000000000005868 157.0
CH2_k127_4370334_0 polyphosphate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000007358 228.0
CH2_k127_4370334_1 CHAD - - - 0.00000000000000000000000000000000000000000000000000000001496 214.0
CH2_k127_4386768_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 529.0
CH2_k127_4386768_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 524.0
CH2_k127_4386768_2 Psort location Cytoplasmic, score 7.50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 436.0
CH2_k127_4386768_3 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 332.0
CH2_k127_4386768_4 hydrolases of the HAD superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000855 335.0
CH2_k127_440530_0 oxidoreductase activity - - - 0.0 1069.0
CH2_k127_440530_1 CoA binding domain - - - 3.387e-317 990.0
CH2_k127_440530_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000004144 216.0
CH2_k127_440530_11 Thioesterase - - - 0.000000000000000000000000000000000000000000000000000000000000477 224.0
CH2_k127_440530_12 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000003598 183.0
CH2_k127_440530_13 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000005642 146.0
CH2_k127_440530_14 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000001367 100.0
CH2_k127_440530_15 Transcriptional regulator - - - 0.0000000000000004479 80.0
CH2_k127_440530_16 FAD linked oxidase domain protein K00103 - 1.1.3.8 0.00000000001007 78.0
CH2_k127_440530_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 5.581e-262 831.0
CH2_k127_440530_3 AcrB/AcrD/AcrF family - - - 2.714e-219 690.0
CH2_k127_440530_4 Acyl-CoA synthetase (NDP forming) K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 630.0
CH2_k127_440530_5 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 586.0
CH2_k127_440530_6 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 591.0
CH2_k127_440530_7 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 502.0
CH2_k127_440530_8 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 416.0
CH2_k127_440530_9 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 339.0
CH2_k127_4449404_0 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 2.013e-241 756.0
CH2_k127_4449404_1 Lactoylglutathione lyase K01759 - 4.4.1.5 0.000000000000000000005434 94.0
CH2_k127_4477604_0 ribonuclease, Rne Rng family K08301 - - 1.624e-224 704.0
CH2_k127_4477604_1 PFAM alanine racemase domain protein K19967 - 4.1.2.42 0.0000000000000000000000000000000000000000000000000000000000000000000002602 243.0
CH2_k127_4477604_2 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001484 210.0
CH2_k127_4477604_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000001743 151.0
CH2_k127_4504058_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 4.013e-296 923.0
CH2_k127_4504058_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 353.0
CH2_k127_4504058_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000003956 104.0
CH2_k127_4558881_0 Methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 464.0
CH2_k127_4558881_1 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 381.0
CH2_k127_4558881_10 GDP-mannose mannosyl hydrolase activity K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000000000000008661 160.0
CH2_k127_4558881_11 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000004507 153.0
CH2_k127_4558881_12 PFAM Sporulation domain protein - - - 0.000000000000000007127 92.0
CH2_k127_4558881_2 PFAM 6-phosphogluconate dehydrogenase NAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008193 375.0
CH2_k127_4558881_3 inositol monophosphatase K01092,K05602 - 3.1.3.15,3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 302.0
CH2_k127_4558881_4 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 292.0
CH2_k127_4558881_5 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000003305 293.0
CH2_k127_4558881_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000004489 229.0
CH2_k127_4558881_7 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.00000000000000000000000000000000000000000000000000000000002161 214.0
CH2_k127_4558881_8 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000005286 201.0
CH2_k127_4558881_9 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.000000000000000000000000000000000000000000002665 178.0
CH2_k127_4659386_0 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 7.464e-212 673.0
CH2_k127_4659386_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000001666 242.0
CH2_k127_4659386_2 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000001368 149.0
CH2_k127_4659386_3 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000006907 126.0
CH2_k127_4757476_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 5.302e-213 680.0
CH2_k127_4757476_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 6.43e-209 663.0
CH2_k127_4757476_10 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 354.0
CH2_k127_4757476_11 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 352.0
CH2_k127_4757476_12 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000003349 195.0
CH2_k127_4757476_13 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000003781 172.0
CH2_k127_4757476_14 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000002168 141.0
CH2_k127_4757476_15 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000000158 100.0
CH2_k127_4757476_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 8.465e-198 632.0
CH2_k127_4757476_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 590.0
CH2_k127_4757476_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 516.0
CH2_k127_4757476_5 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 460.0
CH2_k127_4757476_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 433.0
CH2_k127_4757476_7 Mur ligase middle domain K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 432.0
CH2_k127_4757476_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 413.0
CH2_k127_4757476_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 376.0
CH2_k127_4760021_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 7.975e-212 661.0
CH2_k127_4760021_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 524.0
CH2_k127_4760021_2 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 487.0
CH2_k127_4760021_3 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 441.0
CH2_k127_4760021_4 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 351.0
CH2_k127_4760021_5 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000001911 191.0
CH2_k127_4760021_6 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520 - 1.16.1.1 0.0000000000000000000000000000000000003902 145.0
CH2_k127_4760021_7 Mut7-C ubiquitin - - - 0.00000000000000000000000832 117.0
CH2_k127_4760021_8 - - - - 0.0000000000000005999 83.0
CH2_k127_4763451_0 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 532.0
CH2_k127_4763451_1 nadph quinone oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 421.0
CH2_k127_4763451_2 KR domain K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 356.0
CH2_k127_4763451_3 Glutathione S-transferase, N-terminal domain K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001323 273.0
CH2_k127_4763451_4 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 0.000000000000000000000000000000000000000000001518 167.0
CH2_k127_4763451_5 Stringent starvation protein B K03600 - - 0.00000000000000000000000000000000004225 139.0
CH2_k127_4772165_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1446.0
CH2_k127_4772165_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 554.0
CH2_k127_4772165_2 aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000889 546.0
CH2_k127_4772165_3 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009231 526.0
CH2_k127_4772165_4 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 432.0
CH2_k127_4772165_5 FAD binding domain K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 312.0
CH2_k127_4772165_6 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.000000000000000000000000007836 128.0
CH2_k127_4772165_7 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000003842 98.0
CH2_k127_4774144_0 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 0.0 1066.0
CH2_k127_4774144_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 7.852e-299 921.0
CH2_k127_4774144_2 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 436.0
CH2_k127_4774144_3 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 413.0
CH2_k127_4775549_0 twitching motility protein K02670 - - 2.535e-196 621.0
CH2_k127_4775549_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 583.0
CH2_k127_4775549_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 345.0
CH2_k127_4775549_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003333 272.0
CH2_k127_4775549_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001243 258.0
CH2_k127_4775549_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000003287 209.0
CH2_k127_4775549_6 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000000000003799 203.0
CH2_k127_4775549_7 integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000002861 168.0
CH2_k127_4775549_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000005248 63.0
CH2_k127_4775549_9 Plasmid stability protein K21495 - - 0.0003248 47.0
CH2_k127_4850075_0 Glycolate oxidase subunit GlcD K00104 - 1.1.3.15 4.34e-212 668.0
CH2_k127_4850075_1 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 605.0
CH2_k127_4850075_10 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000005007 91.0
CH2_k127_4850075_11 Histidine kinase K07638 - 2.7.13.3 0.000000000000005339 76.0
CH2_k127_4850075_12 addiction module antidote protein - - - 0.000000000003081 69.0
CH2_k127_4850075_2 glycolate oxidase iron-sulfur subunit K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 523.0
CH2_k127_4850075_3 FAD linked oxidase K00104,K11472 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 410.0
CH2_k127_4850075_4 Domain of unknown function (DUF1932) K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 306.0
CH2_k127_4850075_5 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000006415 226.0
CH2_k127_4850075_6 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000003489 223.0
CH2_k127_4850075_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000004996 216.0
CH2_k127_4850075_8 acetyltransferase - - - 0.00000000000000000000000000000000000001008 153.0
CH2_k127_4850075_9 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000007104 123.0
CH2_k127_4858616_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1739.0
CH2_k127_4858616_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1011.0
CH2_k127_4858616_2 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 625.0
CH2_k127_4858616_3 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 547.0
CH2_k127_4858616_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 337.0
CH2_k127_4858616_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000004337 248.0
CH2_k127_4858616_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000001149 235.0
CH2_k127_4858616_7 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000006572 202.0
CH2_k127_4858616_8 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000001131 126.0
CH2_k127_4858616_9 RNA-binding protein containing KH domain possibly ribosomal protein - - - 0.0000000000000000000000000002157 119.0
CH2_k127_4890141_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 601.0
CH2_k127_4890141_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 553.0
CH2_k127_4890141_2 taurine ABC transporter, periplasmic binding protein K15551 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 433.0
CH2_k127_4890141_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 431.0
CH2_k127_4890141_4 binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 417.0
CH2_k127_4890141_5 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K10831 - 3.6.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 400.0
CH2_k127_4890141_6 Orn/Lys/Arg decarboxylase, major domain K01584 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 289.0
CH2_k127_4890141_7 - - - - 0.000000001134 65.0
CH2_k127_4890141_8 Orn Lys Arg decarboxylase major K01584,K01585 - 4.1.1.19 0.000002135 52.0
CH2_k127_4912539_0 Na Pi-cotransporter II-related protein K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 618.0
CH2_k127_4912539_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K00836 - 2.6.1.19,2.6.1.76 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 562.0
CH2_k127_4912539_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 437.0
CH2_k127_4912539_3 permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000002126 175.0
CH2_k127_491491_0 protein synthesis factor, GTP-binding K06207 - - 1.423e-297 927.0
CH2_k127_491491_1 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 516.0
CH2_k127_491491_2 Magnesium transport protein CorA K03284 - - 0.000000000000000000009818 94.0
CH2_k127_491785_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1474.0
CH2_k127_491785_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 378.0
CH2_k127_491785_2 Solute carrier family 35 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 298.0
CH2_k127_491785_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002781 272.0
CH2_k127_491785_4 Protein of unknown function (DUF465) - - - 0.0000000007459 72.0
CH2_k127_4923581_0 Orn/Lys/Arg decarboxylase, N-terminal domain - - - 0.0 1350.0
CH2_k127_4934223_0 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000001686 250.0
CH2_k127_4934223_1 methyltransferase K03437 - - 0.00000000000000000000000000000000000000000000000000001277 201.0
CH2_k127_4958802_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 4.244e-277 856.0
CH2_k127_4958802_1 cation transport ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000005676 266.0
CH2_k127_4958802_2 Cytochrome oxidase maturation protein cbb3-type - - - 0.0000000000003406 78.0
CH2_k127_4958802_3 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.000000000002142 68.0
CH2_k127_4987815_0 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 467.0
CH2_k127_4987815_1 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 293.0
CH2_k127_5172158_0 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 463.0
CH2_k127_5172158_1 PFAM DEAD DEAH box helicase domain protein - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002303 273.0
CH2_k127_5194612_0 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 335.0
CH2_k127_5194612_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000001622 202.0
CH2_k127_5196874_0 fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 511.0
CH2_k127_5196874_1 Transporter, small conductance mechanosensitive ion channel MscS family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002658 267.0
CH2_k127_5196874_2 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.00000004088 55.0
CH2_k127_5220306_0 DNA topoisomerase III K03169 - 5.99.1.2 4.828e-254 797.0
CH2_k127_5220306_1 Transport of potassium into the cell K03549 - - 8.208e-240 756.0
CH2_k127_5220306_10 RNA polymerase sigma K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 363.0
CH2_k127_5220306_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 375.0
CH2_k127_5220306_12 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 354.0
CH2_k127_5220306_13 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 328.0
CH2_k127_5220306_14 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 305.0
CH2_k127_5220306_15 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 311.0
CH2_k127_5220306_16 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 294.0
CH2_k127_5220306_17 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001068 280.0
CH2_k127_5220306_18 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004776 245.0
CH2_k127_5220306_19 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000007445 237.0
CH2_k127_5220306_2 Dynamin family - - - 2.991e-219 700.0
CH2_k127_5220306_20 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000005315 233.0
CH2_k127_5220306_21 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000004221 227.0
CH2_k127_5220306_22 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000001567 216.0
CH2_k127_5220306_23 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000008011 178.0
CH2_k127_5220306_24 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000000000001335 173.0
CH2_k127_5220306_25 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000005799 153.0
CH2_k127_5220306_26 PFAM DinB family - - - 0.000000000000000000000000000005924 120.0
CH2_k127_5220306_27 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000002257 59.0
CH2_k127_5220306_3 Histidine kinase - - - 4.81e-200 652.0
CH2_k127_5220306_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 571.0
CH2_k127_5220306_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 506.0
CH2_k127_5220306_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 408.0
CH2_k127_5220306_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 410.0
CH2_k127_5220306_8 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 398.0
CH2_k127_5220306_9 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 394.0
CH2_k127_5249264_0 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 397.0
CH2_k127_5249264_1 TIGRFAM TIGR00268 family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 295.0
CH2_k127_5249264_2 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000003616 246.0
CH2_k127_5249264_3 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000000004921 209.0
CH2_k127_5249264_4 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000005626 166.0
CH2_k127_5249264_5 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000001197 143.0
CH2_k127_5249264_6 Predicted integral membrane protein (DUF2282) - - - 0.00000000000000000000000000000000002633 141.0
CH2_k127_5256412_0 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 571.0
CH2_k127_5256412_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 393.0
CH2_k127_5256412_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.00000000000000000000000000000000000000000000000000251 186.0
CH2_k127_5256412_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000005118 167.0
CH2_k127_5256412_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000000007132 147.0
CH2_k127_5256412_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000005376 101.0
CH2_k127_5256412_6 ThiS family K03636 - - 0.000000000000000000207 91.0
CH2_k127_5256412_7 ATP synthase I chain K02116 - - 0.00000000000000008629 85.0
CH2_k127_5292984_0 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 395.0
CH2_k127_5292984_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000005807 136.0
CH2_k127_5292984_2 glycosyl transferase K07011 - - 0.00000000000000000000000000003453 121.0
CH2_k127_5305740_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1109.0
CH2_k127_5305740_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 8.303e-276 856.0
CH2_k127_5305740_2 UPF0114 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001709 259.0
CH2_k127_5305740_3 Histidine Phosphotransfer domain - - - 0.000009895 55.0
CH2_k127_531594_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 371.0
CH2_k127_531594_1 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 302.0
CH2_k127_531594_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000002385 210.0
CH2_k127_531594_3 Type II secretion system K02653 - - 0.000000000000000000965 86.0
CH2_k127_531594_4 - - - - 0.000000000000195 78.0
CH2_k127_5364357_0 AMP-binding enzyme K00666,K20034 - 6.2.1.44 6.094e-290 897.0
CH2_k127_5364357_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 489.0
CH2_k127_5406056_0 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 299.0
CH2_k127_5406056_1 PFAM Multiple antibiotic resistance (MarC)-related K05595 - - 0.00000000000000000000000000000000000000000000000000000000000008518 220.0
CH2_k127_5406056_2 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.0000000000000003635 87.0
CH2_k127_5415669_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000503 515.0
CH2_k127_5415669_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000489 253.0
CH2_k127_5415669_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000706 222.0
CH2_k127_5415669_3 - - - - 0.00000000000000000002293 96.0
CH2_k127_5422294_0 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 571.0
CH2_k127_5433379_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 0.000000000000000000000000004474 122.0
CH2_k127_546105_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 6.993e-206 655.0
CH2_k127_546105_1 e3 binding domain K09699 - 2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 481.0
CH2_k127_546105_2 Transketolase, C-terminal domain K00167 - 1.2.4.4 0.0000000000000000003025 86.0
CH2_k127_5461588_0 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 1.974e-248 774.0
CH2_k127_5461588_1 Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC K01160 - 3.1.22.4 0.0000007814 57.0
CH2_k127_5567813_0 His Kinase A (phospho-acceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 547.0
CH2_k127_5567813_1 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008792 280.0
CH2_k127_5567813_2 - - - - 0.00000000000002202 76.0
CH2_k127_557919_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1428.0
CH2_k127_557919_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 1.641e-204 642.0
CH2_k127_557919_2 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006036 366.0
CH2_k127_557919_3 Beta/Gamma crystallin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001491 280.0
CH2_k127_557919_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000007124 271.0
CH2_k127_557919_5 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000001193 227.0
CH2_k127_557919_6 Psort location CytoplasmicMembrane, score K09793 - - 0.00000000000000000000000000000000000001065 167.0
CH2_k127_557919_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000271 124.0
CH2_k127_557919_8 Protein of unknown function (DUF2442) - - - 0.000000000000000001585 92.0
CH2_k127_557919_9 peptidase S1 and S6, chymotrypsin Hap - - - 0.000002225 61.0
CH2_k127_5636358_0 dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes - - - 8.337e-297 923.0
CH2_k127_5636358_1 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 451.0
CH2_k127_5636358_2 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 404.0
CH2_k127_5636358_3 B12 binding domain K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 306.0
CH2_k127_5636358_4 Bacterial transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000167 209.0
CH2_k127_5636358_5 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000001211 178.0
CH2_k127_5636358_6 PFAM poly granule associated family protein - - - 0.000000000000000000000000022 114.0
CH2_k127_5636358_7 PFAM acyl-coA-binding protein, ACBP - - - 0.000000000000000000000002282 105.0
CH2_k127_56422_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.721e-310 969.0
CH2_k127_56422_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 606.0
CH2_k127_56422_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000005104 246.0
CH2_k127_56422_3 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine - - - 0.000000000000000000000000000002932 125.0
CH2_k127_56422_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000001018 97.0
CH2_k127_5643395_0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005312 574.0
CH2_k127_5643395_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0055114 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002332 268.0
CH2_k127_5643395_2 PFAM CBS domain containing protein - - - 0.0000000000000000000000007452 111.0
CH2_k127_5753984_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1025.0
CH2_k127_5753984_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly - - - 5.701e-266 834.0
CH2_k127_5753984_2 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 585.0
CH2_k127_5753984_3 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 491.0
CH2_k127_5753984_4 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 386.0
CH2_k127_5753984_5 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 345.0
CH2_k127_5753984_6 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.000000000000000000000000000000000000000000000000000000000000001199 224.0
CH2_k127_5753984_7 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS-like protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000002039 186.0
CH2_k127_578812_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 501.0
CH2_k127_578812_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 427.0
CH2_k127_578812_2 RES - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005949 256.0
CH2_k127_578812_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000003177 250.0
CH2_k127_578812_4 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000001839 183.0
CH2_k127_578812_5 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000001606 131.0
CH2_k127_578812_6 Amino-transferase class IV K00824 - 2.6.1.21 0.00000000009036 62.0
CH2_k127_57936_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 7.842e-294 911.0
CH2_k127_57936_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 389.0
CH2_k127_57936_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000001277 211.0
CH2_k127_583178_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 4.87e-253 786.0
CH2_k127_583178_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 3.651e-252 786.0
CH2_k127_583178_2 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 551.0
CH2_k127_583178_3 Acetyltransferase (GNAT) domain K02348 - - 0.000000000000000000000000000000000000000000000008702 184.0
CH2_k127_583178_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000001522 177.0
CH2_k127_583178_5 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000218 132.0
CH2_k127_583178_6 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000003769 116.0
CH2_k127_5887550_0 Methyl-accepting chemotaxis protein K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 600.0
CH2_k127_5887550_1 Histidine kinase K02487,K06596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 364.0
CH2_k127_5887550_2 CheW-like domain K02659 - - 0.00000000000000001034 86.0
CH2_k127_5966943_0 Pyridine nucleotide-disulphide oxidoreductase - - - 6.071e-319 987.0
CH2_k127_5966943_1 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 3.354e-297 923.0
CH2_k127_5966943_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 394.0
CH2_k127_5966943_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 315.0
CH2_k127_5966943_4 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000004165 97.0
CH2_k127_5966943_5 electron transfer activity K03737,K05337 - 1.2.7.1 0.000001671 61.0
CH2_k127_6085145_0 Inorganic H+ pyrophosphatase K15987 - 3.6.1.1 1.512e-202 644.0
CH2_k127_6085145_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000007452 50.0
CH2_k127_6091646_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.754e-255 803.0
CH2_k127_6091646_1 TRAP transporter solute receptor TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 426.0
CH2_k127_6098032_0 Histidine kinase-like ATPases - - - 6.002e-231 742.0
CH2_k127_6098032_1 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 575.0
CH2_k127_6098032_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 432.0
CH2_k127_6098032_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000003744 140.0
CH2_k127_6098032_4 Histidine kinase K20976 - - 0.0000000000000000000005809 101.0
CH2_k127_6120675_0 ABC-type dipeptide transport system, periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009706 265.0
CH2_k127_6120675_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000006903 249.0
CH2_k127_6132272_0 Methylamine dehydrogenase, L chain K15228 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001274 260.0
CH2_k127_6132272_1 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009683 258.0
CH2_k127_6132272_2 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.00000000000000000000000000000000000000000000004522 173.0
CH2_k127_6132272_3 Methylamine utilisation protein MauE - - - 0.00000000000000000000000000000000000001852 151.0
CH2_k127_6132272_4 Cytochrome c - - - 0.00000000000000000000000001296 125.0
CH2_k127_6132272_5 Protein of unknown function (DUF1329) - - - 0.00000000000002088 75.0
CH2_k127_6155704_0 Cytochrome D1 heme domain - - - 9.559e-230 730.0
CH2_k127_6155704_1 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001009 255.0
CH2_k127_6155704_2 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000007503 240.0
CH2_k127_6155704_3 PIN domain - - - 0.000000000000000000000000000000005176 132.0
CH2_k127_6155704_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000000105 108.0
CH2_k127_6183881_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1224.0
CH2_k127_6183881_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 366.0
CH2_k127_6183881_2 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 312.0
CH2_k127_6183881_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000002045 237.0
CH2_k127_6183881_4 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000002214 224.0
CH2_k127_6183881_5 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000001571 197.0
CH2_k127_6183881_6 Protein of unknown function (DUF3299) K09950 - - 0.000000000000000000000000000000005453 141.0
CH2_k127_6183881_7 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.00000000000000000000000000000001447 132.0
CH2_k127_6205992_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.389e-212 670.0
CH2_k127_6205992_1 Rod shape-determining protein MreB K03569 - - 4.506e-197 618.0
CH2_k127_6205992_2 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 471.0
CH2_k127_6205992_3 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008092 268.0
CH2_k127_6205992_4 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000008801 244.0
CH2_k127_6205992_5 shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000001965 161.0
CH2_k127_6205992_6 Glu-tRNAGln amidotransferase C subunit - - - 0.00000000000000000000000004401 112.0
CH2_k127_6211052_0 cyclopropane-fatty-acyl-phospholipid synthase K00574 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 375.0
CH2_k127_6211052_1 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008851 342.0
CH2_k127_6211052_2 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000001158 116.0
CH2_k127_6211052_3 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000003827 59.0
CH2_k127_6215264_0 Domain of unknown function DUF21 K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 598.0
CH2_k127_6215264_1 Phospholipase D. Active site motifs. K06132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 392.0
CH2_k127_6215264_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000001706 259.0
CH2_k127_6215264_3 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000001276 168.0
CH2_k127_6215264_4 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.00000000000005357 79.0
CH2_k127_6219121_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 530.0
CH2_k127_6219121_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000262 222.0
CH2_k127_6219121_2 Acetyltransferases including N-acetylases of ribosomal proteins - - - 0.00000000000000000000000000003716 129.0
CH2_k127_6219121_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000002335 83.0
CH2_k127_6227339_0 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 430.0
CH2_k127_6227339_1 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01032 - 2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 399.0
CH2_k127_6227348_0 COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B K13482 - 1.17.1.4 4.682e-309 955.0
CH2_k127_6227348_1 (ABC) transporter K02056 - 3.6.3.17 2.957e-254 793.0
CH2_k127_6227348_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 533.0
CH2_k127_6227348_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 369.0
CH2_k127_6227348_4 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002151 277.0
CH2_k127_6234692_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 8.614e-316 974.0
CH2_k127_6234692_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.435e-243 757.0
CH2_k127_6234692_2 E1 component K00164 - 1.2.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 567.0
CH2_k127_6234692_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 425.0
CH2_k127_6234692_4 Succinate dehydrogenase hydrophobic membrane anchor protein K00242 - - 0.00000000000000000000000000000000000000000000000000000000001371 211.0
CH2_k127_6234692_5 Succinate dehydrogenase cytochrome b556 subunit K00241 - - 0.00000000000000000000000002592 108.0
CH2_k127_6234692_6 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000004601 89.0
CH2_k127_6345435_0 Zn_pept - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 493.0
CH2_k127_6345435_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 424.0
CH2_k127_6345435_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000006954 219.0
CH2_k127_6374172_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 3.919e-205 661.0
CH2_k127_6374172_1 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 597.0
CH2_k127_6374172_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 441.0
CH2_k127_6374172_3 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.0001061 55.0
CH2_k127_6394163_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 2.12e-222 695.0
CH2_k127_6394163_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 576.0
CH2_k127_6394163_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 500.0
CH2_k127_6394163_3 pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 432.0
CH2_k127_6394163_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 331.0
CH2_k127_6394163_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000001457 236.0
CH2_k127_6394163_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000003024 164.0
CH2_k127_643353_0 NADH flavin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005129 266.0
CH2_k127_6435794_0 Belongs to the IlvD Edd family - - - 1.033e-284 883.0
CH2_k127_6435794_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.564e-245 767.0
CH2_k127_6435794_11 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000000000000002472 149.0
CH2_k127_6435794_12 Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism K13932 - 4.1.1.87 0.00000000000000000009093 104.0
CH2_k127_6435794_13 - - - - 0.0000000000006144 69.0
CH2_k127_6435794_14 Psort location CytoplasmicMembrane, score K07113 - - 0.00000000003957 69.0
CH2_k127_6435794_15 PFAM CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0016043,GO:0022607,GO:0042221,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0046688,GO:0046872,GO:0046914,GO:0050896,GO:0051259,GO:0051260,GO:0065003,GO:0071840 - 0.0000000789 55.0
CH2_k127_6435794_16 - - - - 0.00000008451 63.0
CH2_k127_6435794_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.716e-199 627.0
CH2_k127_6435794_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 561.0
CH2_k127_6435794_4 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009029 437.0
CH2_k127_6435794_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008287 412.0
CH2_k127_6435794_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 334.0
CH2_k127_6435794_7 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 289.0
CH2_k127_6435794_8 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000006629 168.0
CH2_k127_6435794_9 PFAM Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.00000000000000000000000000000000000000004954 158.0
CH2_k127_6439780_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.464e-227 714.0
CH2_k127_6439780_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 454.0
CH2_k127_6439780_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 443.0
CH2_k127_6439780_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000001388 258.0
CH2_k127_6439780_4 Colicin V production K03558 - - 0.00000000000000000000000002583 115.0
CH2_k127_6439780_5 Sporulation related domain K03749 - - 0.0000000000000000005238 97.0
CH2_k127_6439780_6 cytochrome c5 - - - 0.000000291 52.0
CH2_k127_647496_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K18355 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 593.0
CH2_k127_647496_1 Pyridine nucleotide-disulphide oxidoreductase K18359 - 1.2.1.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 481.0
CH2_k127_647496_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 432.0
CH2_k127_647496_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K18357 - 1.2.1.58 0.000000000000000000000000000000000000000000000000000000000000000000000001562 252.0
CH2_k127_647496_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000001492 183.0
CH2_k127_647496_5 4Fe-4S binding domain K18358 - 1.2.1.58 0.000000000000000000000000000000000000000003005 163.0
CH2_k127_647496_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.000000000000000000005701 93.0
CH2_k127_6495156_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1328.0
CH2_k127_6495156_1 acetylornithine aminotransferase K00821,K00840 GO:0003674,GO:0003824,GO:0003992,GO:0004069,GO:0005488,GO:0005515,GO:0006082,GO:0006105,GO:0006520,GO:0006525,GO:0006526,GO:0006527,GO:0006553,GO:0006591,GO:0006593,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009016,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009067,GO:0009084,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0017144,GO:0019545,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0036094,GO:0042450,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043825,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046451,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.11,2.6.1.17,2.6.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 401.0
CH2_k127_6495156_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 337.0
CH2_k127_6495156_3 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000002699 141.0
CH2_k127_6496051_0 Soluble lytic murein transglycosylase L domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009874 493.0
CH2_k127_6496051_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 443.0
CH2_k127_6496051_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 401.0
CH2_k127_6496051_3 epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 293.0
CH2_k127_6496051_4 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000002179 247.0
CH2_k127_6496051_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000002654 238.0
CH2_k127_6496051_6 Gram-negative porin - - - 0.0000000000001855 72.0
CH2_k127_6496051_7 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000001078 63.0
CH2_k127_651257_0 Cytochrome b(N-terminal)/b6/petB - - - 8.834e-237 752.0
CH2_k127_651257_1 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 352.0
CH2_k127_651257_2 - - - - 0.000000000000000000000000000000000000009272 150.0
CH2_k127_651257_3 SCP-2 sterol transfer family - - - 0.0000000000000000000000000002708 119.0
CH2_k127_6524081_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 7.153e-243 761.0
CH2_k127_6524081_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009267 281.0
CH2_k127_6524081_2 cheY-homologous receiver domain K02657 - - 0.000000000000000000000000000000000000000000000000000000000000006039 220.0
CH2_k127_6524081_3 RESPONSE REGULATOR receiver K02658 - - 0.0000000000000000000000000000000000000000000000000013 186.0
CH2_k127_6524081_4 PFAM CheW domain protein K02659 - - 0.000000000000000000000008768 104.0
CH2_k127_65359_0 PFAM General secretion pathway L K02461 - - 0.0000000000000006344 90.0
CH2_k127_65359_1 Type II secretion system (T2SS), protein M - - - 0.000009895 55.0
CH2_k127_6558041_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 496.0
CH2_k127_6558041_1 Permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 373.0
CH2_k127_6558041_2 nitric oxide dioxygenase activity - - - 0.0000000000000000000000000000000000000000001563 163.0
CH2_k127_6558041_3 - - - - 0.0000000000000000000001006 99.0
CH2_k127_6558041_4 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K04757 - 2.7.11.1 0.0000000006524 66.0
CH2_k127_6558041_5 Rhomboid family - - - 0.00002975 49.0
CH2_k127_6568623_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 548.0
CH2_k127_6568623_1 Protein of unknown function (DUF3141) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007727 550.0
CH2_k127_6568623_2 - - - - 0.000000000003966 71.0
CH2_k127_6591407_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.384e-253 788.0
CH2_k127_6591407_1 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 325.0
CH2_k127_6591407_2 MOSC domain protein beta barrel domain protein K07140 - - 0.000000000000000000000000000000000000000000000000000000000000516 220.0
CH2_k127_6595928_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.858e-219 689.0
CH2_k127_6595928_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 451.0
CH2_k127_6595928_3 COG0491 Zn-dependent hydrolases, including glyoxylases - GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 - 0.000000000000000000000000000000003047 135.0
CH2_k127_6595928_4 SAF - - - 0.0000000000000000000006487 98.0
CH2_k127_6629375_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000322 242.0
CH2_k127_6629375_1 esterase lipase K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000000000000000000001184 234.0
CH2_k127_664159_0 Chromate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 624.0
CH2_k127_664159_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009257 497.0
CH2_k127_664159_10 Protein of unknown function (DUF3306) - - - 0.000000000000000000000000005453 121.0
CH2_k127_664159_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 492.0
CH2_k127_664159_3 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007517 463.0
CH2_k127_664159_4 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 430.0
CH2_k127_664159_5 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 388.0
CH2_k127_664159_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 308.0
CH2_k127_664159_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000006235 265.0
CH2_k127_664159_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000009005 155.0
CH2_k127_664159_9 Protein of unknown function (DUF3305) - - - 0.000000000000000000000000000006174 137.0
CH2_k127_6653957_0 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 597.0
CH2_k127_6653957_1 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 284.0
CH2_k127_6653957_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000005141 235.0
CH2_k127_6653957_3 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000004807 143.0
CH2_k127_6653957_4 - - - - 0.000000000000000002235 94.0
CH2_k127_6653957_5 - - - - 0.000000000001072 77.0
CH2_k127_6675443_0 Phospholipase, patatin family K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 556.0
CH2_k127_6675443_1 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 349.0
CH2_k127_6694902_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 376.0
CH2_k127_6694902_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 311.0
CH2_k127_6705355_0 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 526.0
CH2_k127_6705355_1 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002398 262.0
CH2_k127_6705355_2 NMT1-like family K07080 - - 0.00000000000000000000000002484 111.0
CH2_k127_6712278_0 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001231 289.0
CH2_k127_6712278_1 Pfam:DUF989 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009175 276.0
CH2_k127_6712278_2 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000003413 199.0
CH2_k127_6712278_3 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000000000000000000000000001496 173.0
CH2_k127_6712278_4 Ubiquinone biosynthesis hydroxylase - - - 0.0000000000000000000000000000000000004306 155.0
CH2_k127_6714877_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 6.898e-252 788.0
CH2_k127_6714877_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 484.0
CH2_k127_6714877_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000131 54.0
CH2_k127_6718435_0 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 583.0
CH2_k127_6718435_1 -acetyltransferase K00657 - 2.3.1.57 0.0000000000000000000000000000000000000000000000000000000002615 207.0
CH2_k127_6718435_2 Tetratricopeptide repeat - - - 0.0000000000000000004173 92.0
CH2_k127_673023_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 2.857e-244 775.0
CH2_k127_673023_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 1.593e-224 705.0
CH2_k127_673023_10 response regulator K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 308.0
CH2_k127_673023_11 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002396 274.0
CH2_k127_673023_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002062 255.0
CH2_k127_673023_13 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000004165 237.0
CH2_k127_673023_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000009443 215.0
CH2_k127_673023_15 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000000000000000001177 209.0
CH2_k127_673023_16 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000002599 202.0
CH2_k127_673023_17 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000001099 148.0
CH2_k127_673023_18 Domain of unknown function (DUF4440) - - - 0.000000000000000000000000000000000001402 146.0
CH2_k127_673023_19 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000008306 76.0
CH2_k127_673023_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 6.962e-205 651.0
CH2_k127_673023_3 Cys/Met metabolism PLP-dependent enzyme K01739,K01740 - 2.5.1.48,2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 594.0
CH2_k127_673023_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 572.0
CH2_k127_673023_5 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 427.0
CH2_k127_673023_6 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 406.0
CH2_k127_673023_7 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 376.0
CH2_k127_673023_8 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 343.0
CH2_k127_673023_9 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 336.0
CH2_k127_6733172_0 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 440.0
CH2_k127_6733172_1 Phosphotransferase system, mannose fructose-specific component IIA K02821 - 2.7.1.194 0.0000000000000000000000000000000000000000000003002 171.0
CH2_k127_6733172_2 Phosphotransferase System K11189 - - 0.0000000000000000000000000000000006907 135.0
CH2_k127_6736729_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 3.655e-218 699.0
CH2_k127_6736729_1 Glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 538.0
CH2_k127_6736729_2 PhoH-like phosphate starvation-inducible protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 450.0
CH2_k127_6736729_3 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 393.0
CH2_k127_6736729_4 PFAM CBS domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 378.0
CH2_k127_6736729_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000009935 170.0
CH2_k127_6746926_0 Heavy metal transport detoxification protein K17686,K19597 - 3.6.3.54 4.85e-224 717.0
CH2_k127_6746926_1 Cytochrome c554 and c-prime - - - 2.846e-220 734.0
CH2_k127_6746926_2 TrkA-N domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 405.0
CH2_k127_6746926_3 phosphoglycerate mutase K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000007229 231.0
CH2_k127_6746926_4 COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000001913 247.0
CH2_k127_6746926_5 - - - - 0.0000000000000000000000000000000000000000000000000001294 188.0
CH2_k127_6746926_6 Heavy metal-associated domain protein K07213 - - 0.00000000004339 70.0
CH2_k127_6746926_7 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000007448 61.0
CH2_k127_6746926_8 Amidohydrolase family - - - 0.000001772 52.0
CH2_k127_6746926_9 - - - - 0.0002688 48.0
CH2_k127_6747434_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1639.0
CH2_k127_6747434_1 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 364.0
CH2_k127_6747434_2 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 341.0
CH2_k127_6747434_3 Ankyrin repeats (3 copies) K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001707 256.0
CH2_k127_6763148_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1339.0
CH2_k127_6763148_1 response regulator K07684 - - 0.0000000000000000000000000000000000000000000000000000007735 202.0
CH2_k127_6763148_2 Histidine kinase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000007289 197.0
CH2_k127_6763715_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 484.0
CH2_k127_6763715_1 GrpE K03687 - - 0.00000000000000000000000000000000000000000000000000519 187.0
CH2_k127_6783522_0 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 469.0
CH2_k127_6783522_1 Peptidase C13 family - - - 0.0000000000000000000000000000000000000000000000000000000000000006472 233.0
CH2_k127_6788225_0 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 429.0
CH2_k127_6788225_1 Belongs to the peptidase S24 family K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000001107 258.0
CH2_k127_6788225_2 Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000009053 219.0
CH2_k127_6788225_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000001704 169.0
CH2_k127_681210_0 AAA domain - - - 1.016e-251 800.0
CH2_k127_681210_1 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000000000000000000652 175.0
CH2_k127_681210_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000001167 95.0
CH2_k127_6822668_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 6.767e-299 937.0
CH2_k127_6822668_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000004254 143.0
CH2_k127_6830033_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 3.891e-194 616.0
CH2_k127_6830033_1 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 439.0
CH2_k127_6830033_2 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 356.0
CH2_k127_6830033_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000001622 229.0
CH2_k127_6830033_4 Psort location Cytoplasmic, score 8.96 K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000004357 226.0
CH2_k127_6830033_5 branched-chain amino acid K01995 - - 0.0000000000000000000000000000000000000000003472 159.0
CH2_k127_6830033_6 Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors K12973 - 2.3.1.251 0.00000000000000000000000000000000000000002442 160.0
CH2_k127_6830033_7 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000567 100.0
CH2_k127_6830033_8 - - - - 0.0000000001646 71.0
CH2_k127_6856177_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 4.14e-290 910.0
CH2_k127_6856177_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 488.0
CH2_k127_6856177_10 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000008774 50.0
CH2_k127_6856177_2 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 436.0
CH2_k127_6856177_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 392.0
CH2_k127_6856177_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 366.0
CH2_k127_6856177_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 365.0
CH2_k127_6856177_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 334.0
CH2_k127_6856177_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 282.0
CH2_k127_6856177_8 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000003291 229.0
CH2_k127_6856177_9 Belongs to the skp family K06142 - - 0.0000000000000000000000000000000000000000000000000002936 191.0
CH2_k127_6857510_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 509.0
CH2_k127_6857510_1 Histidine kinase K20975 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 379.0
CH2_k127_6857510_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 327.0
CH2_k127_6857510_3 Histidine kinase K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000001143 258.0
CH2_k127_6857510_4 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000004121 205.0
CH2_k127_6857510_5 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000906 185.0
CH2_k127_6857510_6 ATP-independent chaperone mediated protein folding - - - 0.000000003705 65.0
CH2_k127_6868782_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 7.023e-249 775.0
CH2_k127_6868782_1 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 355.0
CH2_k127_6868782_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002862 273.0
CH2_k127_6868782_3 Glycine-zipper domain - - - 0.000000000000000000000000000000000000001195 162.0
CH2_k127_6868782_4 - - - - 0.0000000000000000000000001239 115.0
CH2_k127_6915616_0 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 477.0
CH2_k127_6915616_1 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 376.0
CH2_k127_6915616_2 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 341.0
CH2_k127_6915616_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000001402 240.0
CH2_k127_6938894_0 ErfK YbiS YcfS YnhG family protein K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 426.0
CH2_k127_6938894_1 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000003423 174.0
CH2_k127_6938894_2 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000001228 175.0
CH2_k127_6938894_3 acetyltransferase K22476 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.3.1.1 0.000000000000000002346 90.0
CH2_k127_7040835_0 guanyl-nucleotide exchange factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002241 249.0
CH2_k127_7040835_1 OHCU decarboxylase K13485 - 4.1.1.97 0.00000000000000000000000000000000000000000000000000000002811 201.0
CH2_k127_7040835_2 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.000000000000000000000000000000000000000000008989 171.0
CH2_k127_7040835_3 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000002363 139.0
CH2_k127_7062339_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 399.0
CH2_k127_7062339_1 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 311.0
CH2_k127_7062339_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 287.0
CH2_k127_7062339_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9 0.00009016 44.0
CH2_k127_7071300_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.044e-237 747.0
CH2_k127_7071300_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 561.0
CH2_k127_7071300_2 Mediates influx of magnesium ions K03284,K16074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 393.0
CH2_k127_7074020_0 TIGRFAM malate synthase A K01638 - 2.3.3.9 0.00000000000000000000000000000000000000000000000000000000003182 207.0
CH2_k127_7074020_1 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000007213 180.0
CH2_k127_7087786_0 ABC-type sugar transport system periplasmic component K02027,K05813 - - 7.068e-206 657.0
CH2_k127_7087786_1 ABC-type sugar K02025,K05814,K10118,K17242,K17245 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 455.0
CH2_k127_7087786_2 COG3839 ABC-type sugar transport systems, ATPase components K05816 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 446.0
CH2_k127_7087786_3 PFAM binding-protein-dependent transport systems inner membrane component K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 432.0
CH2_k127_7087786_4 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.0000000000000000000000000000000000000001325 151.0
CH2_k127_7088030_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 508.0
CH2_k127_7088030_1 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 355.0
CH2_k127_7088030_10 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000002147 180.0
CH2_k127_7088030_11 Glutathione-dependent formaldehyde-activating enzyme family protein 4 - - - 0.00000000000000000000000000000000000212 143.0
CH2_k127_7088030_13 PFAM HNH endonuclease K07451 - - 0.0000000000000000000004925 102.0
CH2_k127_7088030_14 Cmp dcmp deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000008612 89.0
CH2_k127_7088030_15 - - - - 0.000000000005696 70.0
CH2_k127_7088030_2 protein-(glutamine-N5) methyltransferase activity K21786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 360.0
CH2_k127_7088030_3 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 334.0
CH2_k127_7088030_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 291.0
CH2_k127_7088030_5 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000368 284.0
CH2_k127_7088030_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009826 271.0
CH2_k127_7088030_7 GNaT family - - - 0.000000000000000000000000000000000000000000000000000004117 195.0
CH2_k127_7088030_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000005235 197.0
CH2_k127_7088030_9 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000000000000003327 179.0
CH2_k127_7089247_0 Belongs to the glycosyl hydrolase 31 family K01811 GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0016787,GO:0016798,GO:0042802,GO:0080176 3.2.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 515.0
CH2_k127_7089247_1 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 327.0
CH2_k127_7089247_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 302.0
CH2_k127_7089247_3 Belongs to the HpcH HpaI aldolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009999 304.0
CH2_k127_7089247_4 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000005231 218.0
CH2_k127_7089247_5 branched-chain amino acid permease (azaleucine resistance) - - - 0.00000000000000000000000000000000000000000000000009933 188.0
CH2_k127_7089247_6 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000001099 82.0
CH2_k127_7089247_7 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000001 64.0
CH2_k127_7091445_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.467e-308 957.0
CH2_k127_7091445_1 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 1.389e-267 878.0
CH2_k127_7091445_2 dihydroorotase K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 603.0
CH2_k127_7091445_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 511.0
CH2_k127_7091445_4 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 326.0
CH2_k127_7091445_5 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001703 267.0
CH2_k127_7091445_6 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000001198 189.0
CH2_k127_7091445_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000004284 154.0
CH2_k127_7091445_8 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000006263 73.0
CH2_k127_7119938_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.177e-223 700.0
CH2_k127_7119938_1 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 409.0
CH2_k127_7131484_0 Tripartite tricarboxylate transporter TctA family K07793 - - 3.165e-236 741.0
CH2_k127_7131484_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 5.834e-195 645.0
CH2_k127_7131484_10 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000007817 214.0
CH2_k127_7131484_11 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000000006377 127.0
CH2_k127_7131484_12 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000001602 96.0
CH2_k127_7131484_13 - - - - 0.00000000003476 69.0
CH2_k127_7131484_14 - K06950 - - 0.0000001454 55.0
CH2_k127_7131484_2 glycolate oxidase subunit GlcD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 563.0
CH2_k127_7131484_3 Sigma-54 interaction domain protein K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 551.0
CH2_k127_7131484_4 M61 glycyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 467.0
CH2_k127_7131484_5 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 358.0
CH2_k127_7131484_6 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 311.0
CH2_k127_7131484_7 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000146 274.0
CH2_k127_7131484_8 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000001687 243.0
CH2_k127_7131484_9 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000001158 225.0
CH2_k127_7148303_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 2.332e-261 816.0
CH2_k127_7148303_1 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000002257 229.0
CH2_k127_7148303_2 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000005724 213.0
CH2_k127_7148303_3 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000005841 191.0
CH2_k127_7148303_4 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000001049 157.0
CH2_k127_7190570_0 Tripartite tricarboxylate transporter TctA family K07793 - - 6.64e-249 777.0
CH2_k127_7190570_1 GcpE protein K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 612.0
CH2_k127_7190570_10 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000007604 172.0
CH2_k127_7190570_11 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000005013 159.0
CH2_k127_7190570_12 Helix-turn-helix domain K15539 - - 0.000000000000000000000000000000000000001729 168.0
CH2_k127_7190570_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 526.0
CH2_k127_7190570_3 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 525.0
CH2_k127_7190570_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 514.0
CH2_k127_7190570_5 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 444.0
CH2_k127_7190570_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000005045 253.0
CH2_k127_7190570_7 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000001761 205.0
CH2_k127_7190570_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000009814 209.0
CH2_k127_7190570_9 type 4 pilus biogenesis protein K02656 - - 0.000000000000000000000000000000000000000000000000000003431 200.0
CH2_k127_7236335_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 2.891e-225 709.0
CH2_k127_7236335_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 510.0
CH2_k127_7236335_2 Transporter - - - 0.000000000000000807 79.0
CH2_k127_7252023_0 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 494.0
CH2_k127_7252023_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 444.0
CH2_k127_7252023_2 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 370.0
CH2_k127_7252023_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000007433 207.0
CH2_k127_7252023_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000006987 173.0
CH2_k127_7252023_5 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000002916 141.0
CH2_k127_7252023_6 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000001959 78.0
CH2_k127_7291674_0 PFAM Protein kinase K11912,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009711 492.0
CH2_k127_7291674_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 335.0
CH2_k127_7291674_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 339.0
CH2_k127_7291674_3 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000002216 261.0
CH2_k127_7291674_4 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000001001 219.0
CH2_k127_7291674_5 PFAM BLUF domain protein - - - 0.00000000000000000000000000000000000000000000000001184 183.0
CH2_k127_7291674_6 Lysin motif - - - 0.00000000000000000000000001632 122.0
CH2_k127_7456183_0 ABC transporter transmembrane region K06147 - - 2.766e-263 827.0
CH2_k127_7456183_1 DNA polymerase X family K02347 - - 2.327e-229 719.0
CH2_k127_7456183_2 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 421.0
CH2_k127_7456183_3 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 373.0
CH2_k127_7456183_4 PFAM Endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 307.0
CH2_k127_7456183_5 transcriptional regulator, ArsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006049 278.0
CH2_k127_7456183_6 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009492 279.0
CH2_k127_7456183_7 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000003509 242.0
CH2_k127_7456183_8 DsrE/DsrF-like family K06039 - - 0.0000000000000000000000000000000000000000000001401 171.0
CH2_k127_7456183_9 oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000008457 162.0
CH2_k127_7498853_0 deiminase K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 493.0
CH2_k127_7498853_1 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 491.0
CH2_k127_7498853_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 398.0
CH2_k127_7498853_3 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 317.0
CH2_k127_7506939_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.014e-275 859.0
CH2_k127_7506939_1 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 369.0
CH2_k127_7506939_2 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000004089 262.0
CH2_k127_7506939_3 Cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000003682 177.0
CH2_k127_7506939_4 dksA traR - - - 0.0000000000000000000000000000001113 129.0
CH2_k127_7506939_5 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000006036 125.0
CH2_k127_7517564_0 Glutaredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 303.0
CH2_k127_7517564_1 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000004333 203.0
CH2_k127_7531978_0 Male sterility protein K22025 - 1.1.1.410 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 405.0
CH2_k127_7531978_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000001102 163.0
CH2_k127_7531978_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000009298 113.0
CH2_k127_7553676_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 559.0
CH2_k127_7553676_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 449.0
CH2_k127_7553676_10 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000001047 107.0
CH2_k127_7553676_11 - - - - 0.0000000000000000866 87.0
CH2_k127_7553676_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 398.0
CH2_k127_7553676_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 413.0
CH2_k127_7553676_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 308.0
CH2_k127_7553676_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 293.0
CH2_k127_7553676_6 NnrS protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004836 259.0
CH2_k127_7553676_7 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000209 233.0
CH2_k127_7553676_8 PFAM response regulator receiver K11443 - - 0.000000000000000000000000000000002876 134.0
CH2_k127_7553676_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000271 111.0
CH2_k127_7557957_0 RmlD substrate binding domain K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 401.0
CH2_k127_7557957_1 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 338.0
CH2_k127_7557957_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 305.0
CH2_k127_7557957_3 lipopolysaccharide heptosyltransferase I K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002616 267.0
CH2_k127_7558041_0 poly(R)-hydroxyalkanoic acid synthase K03821 - - 1.495e-260 818.0
CH2_k127_7558041_1 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 5.431e-213 665.0
CH2_k127_7558041_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 602.0
CH2_k127_7558041_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 366.0
CH2_k127_7558041_4 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000874 185.0
CH2_k127_7558041_5 transcriptional - - - 0.000000000000000000000000000000000007717 146.0
CH2_k127_7558041_6 Lysine transporter LysE - - - 0.0000000000000000000000000000007812 123.0
CH2_k127_7559105_0 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K16846 - 4.2.1.7,4.4.1.24 9.527e-250 780.0
CH2_k127_7559105_1 mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 343.0
CH2_k127_7559105_2 Belongs to the IlvD Edd family K13875 - 4.2.1.25 0.0000008003 57.0
CH2_k127_7569269_0 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 455.0
CH2_k127_7572650_0 FAD linked oxidase - - - 0.0 1628.0
CH2_k127_7572650_1 Protein of unknown function, DUF255 - - - 1.487e-237 756.0
CH2_k127_7572650_2 - - - - 0.0000000000000000000000000000000000000000000000000006124 205.0
CH2_k127_7572650_3 Histidine triad (HIT) protein - - - 0.00000000000000000000000000000000000000000002713 165.0
CH2_k127_7572650_4 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.00000000000000000000000001222 109.0
CH2_k127_7592284_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 442.0
CH2_k127_7592284_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000001994 190.0
CH2_k127_7592284_2 fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000001956 127.0
CH2_k127_7592284_3 Belongs to the UPF0312 family - - - 0.0000000000004479 70.0
CH2_k127_75993_0 ERF superfamily - - - 0.0000000000000000000000000000003492 133.0
CH2_k127_75993_1 NinB protein - - - 0.0000000001653 69.0
CH2_k127_7617821_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 453.0
CH2_k127_7617821_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 341.0
CH2_k127_7636980_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 605.0
CH2_k127_7636980_1 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000389 249.0
CH2_k127_7636980_2 fumarate reductase respiratory complex transmembrane subunit K00246 - - 0.000000000000000000000000000001239 124.0
CH2_k127_7636980_3 ferredoxin - - - 0.00000000000000000003825 90.0
CH2_k127_7645785_0 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661,K07536 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 510.0
CH2_k127_7645785_1 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 463.0
CH2_k127_7645785_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 424.0
CH2_k127_7645785_3 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 369.0
CH2_k127_7645785_4 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 364.0
CH2_k127_7674213_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 554.0
CH2_k127_7674213_1 Tripartite ATP-independent periplasmic transporter - - - 0.00000000000000000000000000000000000000000000000000003811 195.0
CH2_k127_7698_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 439.0
CH2_k127_7698_1 surface antigen K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 357.0
CH2_k127_7698_2 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 327.0
CH2_k127_7698_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003913 248.0
CH2_k127_7727031_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 499.0
CH2_k127_7727031_1 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 477.0
CH2_k127_7727031_2 Subtilase family - - - 0.00000000000000000000000000000000000000000000000001198 185.0
CH2_k127_7790989_0 4Fe-4S single cluster domain - - - 7.435e-207 648.0
CH2_k127_7790989_1 transcriptional regulator AsnC family - - - 0.00000000000000000000000000005864 116.0
CH2_k127_7790989_2 Cytochrome D1 heme domain - - - 0.000000000000000000007122 96.0
CH2_k127_7837215_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1471.0
CH2_k127_7837215_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005119 447.0
CH2_k127_7837215_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000004995 214.0
CH2_k127_7837215_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000005858 113.0
CH2_k127_7847377_0 type II and III secretion system protein K02666 - - 9.306e-212 681.0
CH2_k127_7847377_1 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000001001 241.0
CH2_k127_7847377_2 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000000000000000000000000000000003315 194.0
CH2_k127_7955927_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 7.427e-198 624.0
CH2_k127_7955927_1 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 320.0
CH2_k127_7955927_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 305.0
CH2_k127_7955927_3 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000000004168 217.0
CH2_k127_7955927_4 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000007069 66.0
CH2_k127_7961944_0 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K16846 - 4.4.1.24 2.233e-213 668.0
CH2_k127_7961944_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 363.0
CH2_k127_7961944_2 inositol monophosphatase K01092 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0031403,GO:0031420,GO:0042578,GO:0043167,GO:0043169,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0046872,GO:0047954,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.0000000000000000000000000000000000000000000000000000001183 206.0
CH2_k127_7961944_3 dioxygenase of extradiol dioxygenase family K06991 - - 0.0000000000000000000000000000000000000000000000000000001183 204.0
CH2_k127_7961944_4 SAF K16845 - 4.4.1.24 0.00000000000000000000000000000000000000000006864 160.0
CH2_k127_7967665_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.702e-314 970.0
CH2_k127_7967665_1 Pyridoxal phosphate biosynthesis protein PdxJ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 398.0
CH2_k127_7967665_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 374.0
CH2_k127_7967665_3 Peptidase S24-like K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 330.0
CH2_k127_7967665_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 319.0
CH2_k127_7967665_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003296 255.0
CH2_k127_7967665_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000006524 246.0
CH2_k127_7967665_7 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000104 134.0
CH2_k127_7967665_8 PFAM glutaredoxin 2 - - - 0.0000000000000000007456 90.0
CH2_k127_7967665_9 Domain of unknown function (DUF4845) - - - 0.000000000000006874 83.0
CH2_k127_7975598_0 PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A K01908 - 6.2.1.17 2.656e-316 977.0
CH2_k127_7975598_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 6.739e-220 696.0
CH2_k127_7975598_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 493.0
CH2_k127_7975598_3 PFAM AFG1-family ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 437.0
CH2_k127_7975598_4 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 390.0
CH2_k127_7975598_5 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 344.0
CH2_k127_7975598_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 322.0
CH2_k127_7975598_7 Sigma E regulatory protein, MucB RseB K03598 - - 0.00000000000000000000000000000000000000000000000000000000000000000000162 247.0
CH2_k127_7975598_8 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.000000000000000001407 98.0
CH2_k127_7985236_0 Ethanolamine ammonia lyase large subunit (EutB) K03735 - 4.3.1.7 5.964e-296 934.0
CH2_k127_7985236_1 YaeQ family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001162 234.0
CH2_k127_7985236_2 Belongs to the UPF0303 family - - - 0.0000000000000000000000000000000000000000000000008798 184.0
CH2_k127_7985236_3 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.0000000000000000000000000000000000000000004656 160.0
CH2_k127_7985236_4 ABC transporter substrate binding protein K01989 - - 0.0000000001314 67.0
CH2_k127_7985362_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.962e-209 662.0
CH2_k127_7985362_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 507.0
CH2_k127_7985362_2 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 371.0
CH2_k127_7985362_3 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 330.0
CH2_k127_7985362_4 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002028 287.0
CH2_k127_7985362_5 Tim44 - - - 0.00000000000000000000000000000000000000000000006277 178.0
CH2_k127_7985362_6 Acyl-ACP thioesterase - - - 0.000000000000000000000000000000000000003242 160.0
CH2_k127_7985362_7 SCP-2 sterol transfer family K03690 - - 0.00000000000001396 81.0
CH2_k127_7985678_0 RNB K01147 - 3.1.13.1 1.845e-200 642.0
CH2_k127_7985678_1 AAA domain K07133 - - 1.143e-194 613.0
CH2_k127_7985678_2 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001158 287.0
CH2_k127_7985678_3 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.00000000000000000000000009439 108.0
CH2_k127_7985678_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0001479 46.0
CH2_k127_7986675_0 FtsX-like permease family K02004 - - 1.297e-237 760.0
CH2_k127_7986675_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.119e-224 713.0
CH2_k127_7986675_2 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 455.0
CH2_k127_7986675_3 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003932 289.0
CH2_k127_7986675_4 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009656 272.0
CH2_k127_7986675_5 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005041 261.0
CH2_k127_7986675_6 Alpha beta hydrolase K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000004231 188.0
CH2_k127_7986675_7 Beta/gamma crystallins - - - 0.000000000000000000000000000007738 125.0
CH2_k127_7994465_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 1.515e-318 984.0
CH2_k127_8010085_0 Radical SAM superfamily K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 481.0
CH2_k127_8010085_1 Quinohemoprotein amine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 412.0
CH2_k127_8010085_2 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 409.0
CH2_k127_8010085_3 peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002966 273.0
CH2_k127_8010085_4 Quinohemoprotein amine dehydrogenase, gamma subunit - - - 0.00000000000000000000000000000000000000000000000003172 189.0
CH2_k127_8027463_0 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 4.349e-274 882.0
CH2_k127_8027463_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000001751 152.0
CH2_k127_8027463_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000003138 98.0
CH2_k127_8027463_3 Cytochrome c K08738 - - 0.000000000002524 70.0
CH2_k127_8051341_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 528.0
CH2_k127_8051341_1 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 299.0
CH2_k127_8051341_2 cheY-homologous receiver domain K11443 - - 0.00000000000000000000000000000000000000000003422 175.0
CH2_k127_8051341_3 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000002263 112.0
CH2_k127_8061566_0 type IV-A pilus assembly ATPase PilB K02652 - - 5.354e-251 787.0
CH2_k127_8061566_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 614.0
CH2_k127_8061566_2 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 461.0
CH2_k127_8061566_3 Type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 396.0
CH2_k127_8061566_4 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000007224 201.0
CH2_k127_8061566_5 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000003224 129.0
CH2_k127_8061566_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000139 115.0
CH2_k127_8061566_7 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000065 51.0
CH2_k127_8061566_8 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0001651 44.0
CH2_k127_8079302_0 Membrane-bound lytic murein transglycosylase K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006855 313.0
CH2_k127_8079302_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000001919 207.0
CH2_k127_8079302_2 ApaG domain - - - 0.00000000000000000000000000000000000000000000000000004473 196.0
CH2_k127_8082945_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 3.453e-301 931.0
CH2_k127_8082945_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 404.0
CH2_k127_8082945_2 (Lipo)protein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 334.0
CH2_k127_8082945_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 327.0
CH2_k127_8082945_4 Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 312.0
CH2_k127_8082945_5 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000006596 202.0
CH2_k127_8099572_0 ABC transporter K06020 - 3.6.3.25 2.347e-289 895.0
CH2_k127_8099572_1 ABC transporter K06158 - - 7.976e-216 687.0
CH2_k127_8099572_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.202e-210 670.0
CH2_k127_8099572_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 4.483e-203 644.0
CH2_k127_8099572_4 Major facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 510.0
CH2_k127_8099572_5 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 368.0
CH2_k127_8099572_6 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 322.0
CH2_k127_8099572_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003374 287.0
CH2_k127_8099572_8 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006772 253.0
CH2_k127_8099572_9 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000534 112.0
CH2_k127_8108457_0 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 412.0
CH2_k127_8108457_1 restriction endonuclease K07448 - - 0.000000000000000000000000000000000000000000000008171 179.0
CH2_k127_8108457_2 Protein of unknown function (DUF3095) - - - 0.0000000000006889 74.0
CH2_k127_8108457_3 Protein of unknown function (DUF3095) - - - 0.00000001066 61.0
CH2_k127_8108457_4 KR domain - - - 0.0000002853 55.0
CH2_k127_8108457_5 Transposase domain (DUF772) - - - 0.00001043 51.0
CH2_k127_8122636_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 3.266e-211 663.0
CH2_k127_8122636_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 316.0
CH2_k127_8122636_2 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001518 257.0
CH2_k127_8122636_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000000001338 237.0
CH2_k127_8122636_4 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.000000000000000000000000000000000000000000000000000000002284 203.0
CH2_k127_8122636_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000001091 194.0
CH2_k127_8122636_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000334 141.0
CH2_k127_8122636_7 Ribosomal protein L30 K02907 - - 0.000000000000000004149 85.0
CH2_k127_8122636_8 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000002497 70.0
CH2_k127_8158968_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 469.0
CH2_k127_8158968_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 459.0
CH2_k127_8158968_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000003725 252.0
CH2_k127_8158968_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000003622 211.0
CH2_k127_8158968_4 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000004486 177.0
CH2_k127_8158968_5 Bacterial dnaA protein K10763 - - 0.00000000000000000000000000000000000000000000002549 179.0
CH2_k127_8158968_6 PFAM MscS Mechanosensitive ion channel - - - 0.0000000000000000000000000000006304 129.0
CH2_k127_8158968_7 Protein of unknown function (DUF3108) - - - 0.0000000000000005876 90.0
CH2_k127_8163736_0 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 574.0
CH2_k127_8163736_1 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 309.0
CH2_k127_8163736_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000002016 217.0
CH2_k127_81891_0 Protein of unknown function (DUF3604) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 425.0
CH2_k127_81891_1 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005921 240.0
CH2_k127_81891_2 Transglycosylase associated protein - - - 0.0000000000000000000000000000000000006632 141.0
CH2_k127_81891_4 HupE / UreJ protein - - - 0.0000000001685 66.0
CH2_k127_8219637_0 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 539.0
CH2_k127_8219637_1 Psort location Cytoplasmic, score 7.50 - - - 0.0000000000000000000000000002408 115.0
CH2_k127_8245490_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 3.039e-283 887.0
CH2_k127_8245490_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 9.539e-258 807.0
CH2_k127_8245490_2 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.41e-226 717.0
CH2_k127_8260202_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.621e-298 920.0
CH2_k127_8260202_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 498.0
CH2_k127_8260202_10 signal sequence binding - - - 0.00000000000000000000000000000002667 142.0
CH2_k127_8260202_11 Rubredoxin - - - 0.0000000000000000000000000002768 114.0
CH2_k127_8260202_12 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000001002 108.0
CH2_k127_8260202_13 Protein of unknown function (DUF2909) - - - 0.0000006151 61.0
CH2_k127_8260202_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 414.0
CH2_k127_8260202_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 404.0
CH2_k127_8260202_4 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 392.0
CH2_k127_8260202_5 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005964 268.0
CH2_k127_8260202_6 oxidase assembly K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000000001426 243.0
CH2_k127_8260202_7 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000003928 219.0
CH2_k127_8260202_8 SURF1 family - - - 0.0000000000000000000000000000000000000000000000005147 184.0
CH2_k127_8260202_9 Aminotransferase K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000001222 169.0
CH2_k127_8274486_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 410.0
CH2_k127_8274486_1 abc transporter K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003489 273.0
CH2_k127_8274486_2 peptidase m48, ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004142 256.0
CH2_k127_8274486_3 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000000000000002097 89.0
CH2_k127_8294521_0 enoyl-CoA hydratase K15513 - 4.1.2.44 1.509e-265 827.0
CH2_k127_8294521_1 benzoyl-CoA oxygenase K15512 - 1.14.13.208 2.435e-251 782.0
CH2_k127_8294521_10 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000000000000000002475 192.0
CH2_k127_8294521_11 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.000000000000000000000000000000000000000000000008442 178.0
CH2_k127_8294521_12 Hemerythrin HHE cation binding - - - 0.00000000000000000000000000000000000000000000005929 179.0
CH2_k127_8294521_13 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000000000000000000001653 183.0
CH2_k127_8294521_14 periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000000000004505 173.0
CH2_k127_8294521_15 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000001285 163.0
CH2_k127_8294521_16 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000002889 156.0
CH2_k127_8294521_17 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000001878 140.0
CH2_k127_8294521_18 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000001306 129.0
CH2_k127_8294521_19 Invasion gene expression up-regulator SirB - - - 0.0000000000000000000000000000009971 130.0
CH2_k127_8294521_2 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 2.796e-194 613.0
CH2_k127_8294521_20 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000006955 119.0
CH2_k127_8294521_21 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000004524 103.0
CH2_k127_8294521_22 RDD family - - - 0.000001202 62.0
CH2_k127_8294521_23 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000001202 62.0
CH2_k127_8294521_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 589.0
CH2_k127_8294521_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 363.0
CH2_k127_8294521_5 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 320.0
CH2_k127_8294521_6 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000001449 275.0
CH2_k127_8294521_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000004261 262.0
CH2_k127_8294521_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000001513 212.0
CH2_k127_8294521_9 Domain of unknown function (DUF4863) - - - 0.0000000000000000000000000000000000000000000000000000000001397 207.0
CH2_k127_8308316_0 antiporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 464.0
CH2_k127_8308316_1 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000007109 193.0
CH2_k127_8466484_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1920.0
CH2_k127_8466484_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 346.0
CH2_k127_8466484_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 314.0
CH2_k127_8466484_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006255 262.0
CH2_k127_8466484_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000003681 240.0
CH2_k127_8466484_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000002245 172.0
CH2_k127_8466484_6 SecE/Sec61-gamma subunits of protein translocation complex K03073 - - 0.000000000000000000000000000001373 124.0
CH2_k127_8466484_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000003462 89.0
CH2_k127_8466484_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000002101 55.0
CH2_k127_8499416_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 8.33e-210 659.0
CH2_k127_8499416_1 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.00000000000000000000000000000000000000000000000000002197 193.0
CH2_k127_8499416_2 PFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000001513 178.0
CH2_k127_8499416_3 C4-dicarboxylate ABC transporter substrate-binding protein - - - 0.0000000000000000000000000000000000000000000004056 168.0
CH2_k127_8514443_0 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 309.0
CH2_k127_8514443_1 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000002556 261.0
CH2_k127_8514443_2 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003515 251.0
CH2_k127_8523781_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 0.0 1637.0
CH2_k127_8523781_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 488.0
CH2_k127_8523781_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 455.0
CH2_k127_8523781_3 COG3264 Small-conductance mechanosensitive channel K05802 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 316.0
CH2_k127_8565791_0 Peptidase family M41 K03798 - - 3.716e-258 808.0
CH2_k127_8565791_1 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 533.0
CH2_k127_8565791_10 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000001983 138.0
CH2_k127_8565791_11 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000243 111.0
CH2_k127_8565791_12 Sensors of blue-light using FAD - - - 0.00000000000000000000008142 102.0
CH2_k127_8565791_13 COGs COG2929 conserved K09803 - - 0.000000000000000000001058 95.0
CH2_k127_8565791_14 PFAM regulatory protein, MerR K22491 - - 0.0000000000001814 83.0
CH2_k127_8565791_15 Protein of unknown function (DUF3237) - - - 0.00006654 53.0
CH2_k127_8565791_2 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 487.0
CH2_k127_8565791_3 Bacterial regulatory helix-turn-helix protein, lysR family K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 415.0
CH2_k127_8565791_4 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 374.0
CH2_k127_8565791_5 Polycystin cation channel K08714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 296.0
CH2_k127_8565791_6 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000001175 223.0
CH2_k127_8565791_7 GTP cyclohydrolase K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000004336 213.0
CH2_k127_8565791_8 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.000000000000000000000000000000000000000000000000006281 184.0
CH2_k127_8565791_9 Prokaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000001735 183.0
CH2_k127_8582505_0 Transcriptional regulator K03603,K05799 - - 1.962e-262 837.0
CH2_k127_8582505_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002825 251.0
CH2_k127_8638417_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 405.0
CH2_k127_8638417_1 Rubredoxin - - - 0.0000000000000000000000000007558 116.0
CH2_k127_8638417_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000005012 106.0
CH2_k127_866178_0 4Fe-4S dicluster domain - - - 0.0 1465.0
CH2_k127_866178_1 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 1.081e-238 753.0
CH2_k127_866178_2 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 610.0
CH2_k127_866178_3 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 603.0
CH2_k127_866178_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 572.0
CH2_k127_866178_5 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 380.0
CH2_k127_866178_6 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 368.0
CH2_k127_866178_7 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000000000005649 174.0
CH2_k127_866178_8 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000649 95.0
CH2_k127_866178_9 molybdate-binding protein K02020 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0040007,GO:0042597,GO:0043167,GO:0043168,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0051704 - 0.00000000000000000123 99.0
CH2_k127_8768482_0 4-alpha-glucanotransferase K01214,K02438 - 3.2.1.196,3.2.1.68 0.0 1428.0
CH2_k127_8768482_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1066.0
CH2_k127_8768482_2 ABC-type Fe3 transport system permease component K02011 - - 2.819e-253 801.0
CH2_k127_8768482_3 Nucleotidyl transferase K00975 - 2.7.7.27 1.028e-208 661.0
CH2_k127_8768482_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 1.469e-194 619.0
CH2_k127_8768482_5 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 603.0
CH2_k127_8768482_6 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 445.0
CH2_k127_8768482_7 Bacterial extracellular solute-binding protein K02012,K11081 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 372.0
CH2_k127_8768482_8 acyl-CoA dehydrogenase K09456,K20035 - - 0.000000000000000000000000000000000504 136.0
CH2_k127_8904798_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001089 258.0
CH2_k127_8904798_1 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000000000000000901 208.0
CH2_k127_8904798_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000001409 65.0
CH2_k127_8916275_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 515.0
CH2_k127_8916275_1 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 483.0
CH2_k127_8916275_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 302.0
CH2_k127_8916275_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000000000000003447 178.0
CH2_k127_8916275_4 DNA polymerase III tau subunit V interacting with alpha K02343 - 2.7.7.7 0.000000000000000000000000000000000003625 148.0
CH2_k127_8917035_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.457e-296 920.0
CH2_k127_8917035_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 338.0
CH2_k127_8917035_2 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000006309 125.0
CH2_k127_8919539_0 Thiamine pyrophosphate enzyme, central domain K04103 - 4.1.1.74 5.549e-251 784.0
CH2_k127_8919539_1 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.041e-215 679.0
CH2_k127_8919539_10 PFAM AMMECR1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001204 225.0
CH2_k127_8919539_11 hydrogenase maturation protease - - - 0.0000000000000000000000000000000000003707 149.0
CH2_k127_8919539_12 MazG-like family - - - 0.000000000000000000000000000000003357 132.0
CH2_k127_8919539_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 - 1.12.1.2 3.308e-197 620.0
CH2_k127_8919539_3 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 586.0
CH2_k127_8919539_4 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 413.0
CH2_k127_8919539_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 372.0
CH2_k127_8919539_6 mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 332.0
CH2_k127_8919539_7 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 328.0
CH2_k127_8919539_8 Protein of unknown function, DUF480 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 288.0
CH2_k127_8919539_9 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001187 289.0
CH2_k127_8937977_0 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 409.0
CH2_k127_8937977_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000001469 193.0
CH2_k127_8937977_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000007016 153.0
CH2_k127_8938412_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 1.049e-308 954.0
CH2_k127_8938412_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000001212 183.0
CH2_k127_8938412_2 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.0000000000000000000000000000006039 125.0
CH2_k127_8938412_3 Cytochrome c K08738 - - 0.000000000000000000000000001286 116.0
CH2_k127_8938412_4 cytochrome d1 heme K19345 - - 0.0000000000000000000000004446 106.0
CH2_k127_8938898_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 6.537e-208 677.0
CH2_k127_8938898_1 NADH flavin oxidoreductase NADH oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 545.0
CH2_k127_8938898_10 Rubrerythrin - - - 0.00000000000000000000000000000005227 143.0
CH2_k127_8938898_2 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 466.0
CH2_k127_8938898_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 420.0
CH2_k127_8938898_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 419.0
CH2_k127_8938898_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001352 234.0
CH2_k127_8938898_6 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000000000000000101 201.0
CH2_k127_8938898_7 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000000000001815 206.0
CH2_k127_8938898_8 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000275 174.0
CH2_k127_8938898_9 thioesterase K01075 - 3.1.2.23 0.000000000000000000000000000000000004735 141.0
CH2_k127_8953813_0 PFAM ABC transporter K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 411.0
CH2_k127_8953813_1 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 342.0
CH2_k127_8953813_2 Belongs to the arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 311.0
CH2_k127_8953813_3 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000494 285.0
CH2_k127_8953813_4 Molybdenum ABC transporter K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008552 273.0
CH2_k127_8953813_5 Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000000007733 143.0
CH2_k127_8953813_6 AAA domain K07028 - - 0.0000000000000000006669 91.0
CH2_k127_8962022_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004332 290.0
CH2_k127_8962022_1 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001382 269.0
CH2_k127_8966660_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000004513 162.0
CH2_k127_8966660_1 LURP-one-related - - - 0.000000000000002711 80.0
CH2_k127_8982010_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 6.988e-217 681.0
CH2_k127_8982010_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.863e-211 676.0
CH2_k127_8982010_2 Glycosyl transferase K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 380.0
CH2_k127_8982010_3 response regulator K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 296.0
CH2_k127_8982010_4 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003113 288.0
CH2_k127_8982010_5 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000001694 242.0
CH2_k127_8982395_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 4.003e-300 944.0
CH2_k127_8982395_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 427.0
CH2_k127_8982395_2 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 415.0
CH2_k127_8982395_3 Sodium Bile acid symporter family - - - 0.0000000000000000000000000000000000000000000000000000001617 204.0
CH2_k127_8982395_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000007921 74.0
CH2_k127_8985015_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 333.0
CH2_k127_8985015_1 helix_turn_helix, Lux Regulon - - - 0.000000003365 65.0
CH2_k127_8997057_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1316.0
CH2_k127_8997057_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 505.0
CH2_k127_8997057_10 DUF167 K09131 - - 0.000000000000000000005437 95.0
CH2_k127_8997057_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 496.0
CH2_k127_8997057_3 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 381.0
CH2_k127_8997057_4 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 343.0
CH2_k127_8997057_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 310.0
CH2_k127_8997057_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002428 247.0
CH2_k127_8997057_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000008337 213.0
CH2_k127_8997057_8 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000004173 168.0
CH2_k127_8997057_9 Methyltransferase domain - - - 0.00000000000000000000000000000000002103 135.0
CH2_k127_8997978_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1032.0
CH2_k127_8997978_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.104e-271 846.0
CH2_k127_8997978_2 Participates in both transcription termination and antitermination K02600 - - 1.327e-203 642.0
CH2_k127_8997978_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 312.0
CH2_k127_8997978_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000009529 141.0
CH2_k127_8997978_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000007546 141.0
CH2_k127_9007592_0 Belongs to the peptidase M16 family K07263 - - 3.682e-279 885.0
CH2_k127_9007592_1 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 414.0
CH2_k127_9007592_2 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 357.0
CH2_k127_9007592_3 Belongs to the DegT DnrJ EryC1 family K20429 - 2.6.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 311.0
CH2_k127_9007592_4 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 291.0
CH2_k127_9007592_5 Membrane - - - 0.000000000001664 72.0
CH2_k127_9019318_0 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 589.0
CH2_k127_9019318_1 Phenylacetic acid degradation B K02610 - - 0.0000000000000000000000000000000006399 131.0
CH2_k127_9019318_2 PaaX-like protein K02616 GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0006082,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006805,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010124,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0010817,GO:0016054,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019439,GO:0019748,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032774,GO:0032787,GO:0034641,GO:0034645,GO:0034654,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043170,GO:0043254,GO:0043436,GO:0043565,GO:0044087,GO:0044212,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044282,GO:0045892,GO:0045934,GO:0046395,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0098754,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901575,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.000000000000000000000000000003637 123.0
CH2_k127_9026650_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.72e-279 879.0
CH2_k127_9026650_1 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001664 261.0
CH2_k127_9026650_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002089 259.0
CH2_k127_9026650_3 NUDIX hydrolase K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000001623 194.0
CH2_k127_9026650_4 guanine-specific ribonuclease N1 and T1 K01167 - 3.1.27.3 0.0000000000000000000000000000000000000005809 152.0
CH2_k127_9026650_5 Regulatory protein, FmdB family - - - 0.00000000000000000000000001353 113.0
CH2_k127_9026650_6 Barstar (barnase inhibitor) - - - 0.000000000000000002357 91.0
CH2_k127_9026650_7 Protein of unknown function (DUF541) - - - 0.0000000000000004286 91.0
CH2_k127_9027868_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 594.0
CH2_k127_9027868_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000001967 178.0
CH2_k127_9027868_2 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K12141 - - 0.000000000000000000000000000000000000000000000007447 173.0
CH2_k127_9031748_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 383.0
CH2_k127_9031748_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 312.0
CH2_k127_9031748_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000001276 231.0
CH2_k127_9031748_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000006661 145.0
CH2_k127_9031748_4 SAF K16845 - 4.4.1.24 0.000000000000000000000000000000000001248 141.0
CH2_k127_9031748_5 D-galactarate dehydratase / Altronate hydrolase, C terminus K16846,K16850 - 4.2.1.7,4.4.1.24 0.00000000000000000000001213 102.0
CH2_k127_9092951_0 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 559.0
CH2_k127_9092951_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 419.0
CH2_k127_9092951_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 325.0
CH2_k127_9092951_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 320.0
CH2_k127_9092951_4 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000000000000000000000000001362 212.0
CH2_k127_9092951_5 redox protein, regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000002265 161.0
CH2_k127_9092951_6 Peptidase S24-like - - - 0.000000000000000000000000000001699 124.0
CH2_k127_9092951_7 - - - - 0.0000000000000000009024 91.0
CH2_k127_9092951_8 - - - - 0.0000000001466 67.0
CH2_k127_9096410_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 2.19e-206 647.0
CH2_k127_9096410_1 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 384.0
CH2_k127_9099276_0 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 379.0
CH2_k127_9099276_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000003109 95.0
CH2_k127_9210209_0 Belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 2.608e-213 674.0
CH2_k127_9210209_1 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 494.0
CH2_k127_9210209_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 469.0
CH2_k127_9210209_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 399.0
CH2_k127_9210209_4 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 385.0
CH2_k127_9210209_5 SnoaL-like domain - - - 0.000000002165 68.0
CH2_k127_9233_0 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 333.0
CH2_k127_9233_1 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007692 275.0
CH2_k127_9233_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000006061 100.0
CH2_k127_9253038_0 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 347.0
CH2_k127_9253038_1 Permease YjgP YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 311.0
CH2_k127_9253038_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000001274 163.0
CH2_k127_9253038_3 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000142 134.0
CH2_k127_9285376_0 AAA domain K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 587.0
CH2_k127_9285376_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000001257 241.0
CH2_k127_9285376_2 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000113 187.0
CH2_k127_9285376_3 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000000000000000000000000009282 167.0
CH2_k127_9285376_4 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000001593 104.0
CH2_k127_9366985_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 478.0
CH2_k127_9366985_1 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 457.0
CH2_k127_9366985_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000001376 221.0
CH2_k127_9366985_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000008322 99.0
CH2_k127_9368326_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 1.957e-320 1005.0
CH2_k127_9368326_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 291.0
CH2_k127_9386969_0 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 0.0 1181.0
CH2_k127_9386969_1 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 407.0
CH2_k127_9386969_2 Predicted Permease Membrane Region K07085 - - 0.0000000000000000000000000000000000000000000000000000001443 196.0
CH2_k127_9387476_0 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 326.0
CH2_k127_9387476_1 Protein of unknown function (DUF3750) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006467 252.0
CH2_k127_9387476_2 ribonuclease activity - - - 0.000000000000000000000000000000000007761 144.0
CH2_k127_9387476_3 positive regulation of growth - - - 0.000000000000008124 76.0
CH2_k127_9392335_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 2.213e-284 882.0
CH2_k127_9392335_1 SMART Tetratricopeptide domain protein - - - 5.353e-223 720.0
CH2_k127_9392335_2 Dehydratase large subunit K01699,K06120 - 4.2.1.28,4.2.1.30 8.552e-206 665.0
CH2_k127_9392335_3 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000187 237.0
CH2_k127_9392335_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000007446 198.0
CH2_k127_9392335_5 Dehydratase medium subunit K06121,K13919 - 4.2.1.28,4.2.1.30 0.000000000000000000000000000000000000002997 168.0
CH2_k127_9392335_6 Cytochrome c - - - 0.0000000000000000000000006005 111.0
CH2_k127_9392335_7 Protein of unknown function (DUF2788) - - - 0.000000000000000000000001323 104.0
CH2_k127_9392335_8 Dehydratase small subunit K13920 - 4.2.1.28 0.0000000000000000000005592 101.0
CH2_k127_9392335_9 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000005576 85.0
CH2_k127_9395745_0 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000008926 214.0
CH2_k127_9401872_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 511.0
CH2_k127_9401872_1 Pfam Binding-protein-dependent transport systems inner membrane component K02054,K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 368.0
CH2_k127_9411386_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 8.881e-255 796.0
CH2_k127_9411386_1 peptidase, U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009728 511.0
CH2_k127_9411386_2 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 456.0
CH2_k127_9411386_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 314.0
CH2_k127_9411386_4 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 295.0
CH2_k127_9411386_5 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000003593 239.0
CH2_k127_9411386_6 glycosyl transferase family - - - 0.0000000000000000000000001432 115.0
CH2_k127_9411386_7 Uncharacterized conserved protein (DUF2249) - - - 0.00000000000000006648 85.0
CH2_k127_9411386_8 - - - - 0.0000000000009551 72.0
CH2_k127_9421433_0 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 307.0
CH2_k127_9421433_1 - - - - 0.00000000000000000000000000000000000000000000000000000002706 205.0
CH2_k127_9421433_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000002255 79.0
CH2_k127_9424789_0 PFAM sulfatase - - - 1.303e-205 667.0
CH2_k127_9424789_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 576.0
CH2_k127_9424789_10 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0008329 48.0
CH2_k127_9424789_2 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 589.0
CH2_k127_9424789_3 Response regulator of the LytR AlgR family K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000016 252.0
CH2_k127_9424789_4 AMP-binding enzyme C-terminal domain K22133 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0005782,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016020,GO:0016021,GO:0016054,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0031090,GO:0031224,GO:0031903,GO:0031907,GO:0031974,GO:0033609,GO:0033611,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044425,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0050203,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0072521,GO:0097159,GO:0098588,GO:0098805,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1901575 6.2.1.8 0.000000000000000000000000000000000000000000000006046 188.0
CH2_k127_9424789_5 chain release factor K15034 - - 0.000000000000000000000000000000000000000000008111 166.0
CH2_k127_9424789_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000001636 179.0
CH2_k127_9424789_7 Membrane protein involved in D-alanine export - - - 0.0000000000000000000000000000000000000003072 166.0
CH2_k127_9424789_8 Histidine kinase - - - 0.00000000000000000000004278 116.0
CH2_k127_9424789_9 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000001301 61.0
CH2_k127_9428454_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.655e-320 992.0
CH2_k127_9428454_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 2.494e-286 894.0
CH2_k127_9428454_2 His Kinase A (phospho-acceptor) domain - - - 2.109e-228 721.0
CH2_k127_9428454_3 DNA polymerase III K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 623.0
CH2_k127_9428454_4 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 429.0
CH2_k127_9428454_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000003869 160.0
CH2_k127_9428454_6 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000009275 149.0
CH2_k127_9428454_7 Domain of unknown function (DUF4212) - - - 0.0000000000000000000000000000007812 123.0
CH2_k127_9428454_8 - - - - 0.00000000000000006696 85.0
CH2_k127_9428454_9 - - - - 0.0000000000000001415 86.0
CH2_k127_9452415_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009997 262.0
CH2_k127_9452415_1 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000002314 212.0
CH2_k127_9452415_2 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000001382 204.0
CH2_k127_9531611_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 481.0
CH2_k127_9531611_1 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 465.0
CH2_k127_9531611_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 323.0
CH2_k127_9531611_3 Periplasmic binding protein K02016,K06858 - - 0.000000000000000000000000000000000000000000000000000000000000000000001006 271.0
CH2_k127_9531611_4 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000001402 243.0
CH2_k127_9531611_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000001999 156.0
CH2_k127_9555185_0 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 1.892e-207 658.0
CH2_k127_9555185_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001559 131.0
CH2_k127_9555304_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 1.671e-204 647.0
CH2_k127_9555304_1 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 439.0
CH2_k127_9555304_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000003096 59.0
CH2_k127_9563967_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 3.149e-245 763.0
CH2_k127_9563967_1 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 297.0
CH2_k127_9563967_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000006747 185.0
CH2_k127_9563967_3 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000006236 169.0
CH2_k127_9563967_4 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000004634 141.0
CH2_k127_9563967_5 protein involved in tolerance to divalent cations K03926 - - 0.00000000000000000000000000000003983 127.0
CH2_k127_9563967_6 TIGRFAM MJ0042 family finger-like protein - - - 0.00000000000000000000001212 115.0
CH2_k127_959998_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 449.0
CH2_k127_959998_1 - - - - 0.000000000000808 74.0
CH2_k127_959998_2 GCN5-related N-acetyl-transferase K06975 - - 0.0000004986 51.0
CH2_k127_9625792_0 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 367.0
CH2_k127_9625792_1 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004192 251.0
CH2_k127_9625792_2 Evidence 4 Homologs of previously reported genes of K09700 - - 0.000000000000000000000000000000000000000001485 158.0
CH2_k127_9625792_3 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000008888 122.0
CH2_k127_963040_0 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 2.62e-242 761.0
CH2_k127_963040_1 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 564.0
CH2_k127_963040_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 546.0
CH2_k127_963040_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 516.0
CH2_k127_977669_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 512.0
CH2_k127_977669_1 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000001193 222.0
CH2_k127_977669_2 - - - - 0.0000000000000000000000000000000000000008737 161.0
CH2_k127_977669_3 Protein of unknown function (DUF3301) - - - 0.00000000000000000000008488 103.0
CH2_k127_9832848_0 thiamine transport K02011 - - 1.961e-228 719.0
CH2_k127_9832848_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 567.0
CH2_k127_9832848_2 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 507.0
CH2_k127_9832848_3 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 370.0
CH2_k127_9832848_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000695 192.0
CH2_k127_9832848_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000007652 93.0
CH2_k127_986317_0 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009083 358.0
CH2_k127_986317_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002134 245.0
CH2_k127_986317_2 ribonuclease activity - - - 0.00000000000000000000000000000000000000000000009315 171.0
CH2_k127_986317_3 SpoVT AbrB like domain - - - 0.00000000001355 68.0
CH2_k127_9870519_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1232.0
CH2_k127_9870519_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000007865 227.0
CH2_k127_9870519_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000006567 113.0
CH2_k127_9909271_0 HELICc2 K03722 - 3.6.4.12 5.04e-238 762.0
CH2_k127_9909271_1 Psort location Cytoplasmic, score 8.96 K07462 - - 5.444e-211 670.0
CH2_k127_9909271_10 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000001464 173.0
CH2_k127_9909271_2 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 595.0
CH2_k127_9909271_3 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 488.0
CH2_k127_9909271_4 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 463.0
CH2_k127_9909271_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 372.0
CH2_k127_9909271_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 338.0
CH2_k127_9909271_7 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 308.0
CH2_k127_9909271_8 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002628 274.0
CH2_k127_9909271_9 ZIP Zinc transporter K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000001498 242.0
CH2_k127_9935901_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 596.0
CH2_k127_9935901_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000008672 114.0
CH2_k127_994839_0 ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 6.982e-237 735.0
CH2_k127_994839_1 Isocitrate/isopropylmalate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 402.0
CH2_k127_994839_2 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 388.0
CH2_k127_994839_3 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000385 282.0
CH2_k127_994839_4 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000004033 241.0
CH2_k127_994839_5 Anaerobic ribonucleoside-triphosphate reductase - - - 0.000000000000000000001102 96.0
CH2_k127_998937_0 asparaginyl-tRNA synthetase K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 2.849e-233 731.0
CH2_k127_998937_1 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 341.0
CH2_k127_998937_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000002269 66.0