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Overview

ID MAG00241
Name CH2_bin.25
Sample SMP0008
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Holophagae
Order Holophagales
Family Holophagaceae
Genus JADJVL01
Species
Assembly information
Completeness (%) 81.1
Contamination (%) 3.07
GC content (%) 69.0
N50 (bp) 5,586
Genome size (bp) 2,518,233

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2218

Gene name Description KEGG GOs EC E-value Score Sequence
CH2_k127_10044359_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.095e-315 975.0
CH2_k127_10044359_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 451.0
CH2_k127_10044359_2 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 413.0
CH2_k127_10044359_3 arsenate reductase (glutaredoxin) activity K00537,K04069,K05521,K16509 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1,1.97.1.4,3.2.2.24 0.000000000000000000000000000000000000000000000001341 185.0
CH2_k127_10071282_0 DNA-directed DNA polymerase activity K02337,K14162 - 2.7.7.7 0.0 1123.0
CH2_k127_10075009_0 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 555.0
CH2_k127_10075009_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 303.0
CH2_k127_10075009_2 Alanine-glyoxylate amino-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 303.0
CH2_k127_10075009_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000004357 148.0
CH2_k127_10075009_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000004951 84.0
CH2_k127_10075009_5 Subtilase family K14645 - - 0.0000000000000004939 88.0
CH2_k127_10094723_0 TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type K00123 - 1.17.1.9 1.423e-241 762.0
CH2_k127_10094723_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.000000000000000000000000000000000000005713 147.0
CH2_k127_10136144_0 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007653 415.0
CH2_k127_10136144_1 Aldehyde dehydrogenase family K04021 - - 0.000000000000000000000000000000000000000000000000000000000000003635 222.0
CH2_k127_10136144_2 to Propanediol utilization protein PduT of Enterobacteriaceae UniRef RepID B1ER85_9ESCH - - - 0.000000000000000000000000001931 120.0
CH2_k127_10136144_3 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000009435 78.0
CH2_k127_10136144_4 Ethanolamine utilisation protein EutN/carboxysome K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.000000303 57.0
CH2_k127_10171256_0 Aminotransferase K00813,K00832 GO:0003674,GO:0003824,GO:0004069,GO:0004838,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0008793,GO:0009058,GO:0009066,GO:0009067,GO:0009072,GO:0009073,GO:0009081,GO:0009082,GO:0009094,GO:0009095,GO:0009098,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019292,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0033585,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050048,GO:0050662,GO:0070279,GO:0070547,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.6.1.1,2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 494.0
CH2_k127_10171256_1 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000007508 187.0
CH2_k127_10171256_2 Ras family - - - 0.0001133 44.0
CH2_k127_10180996_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.182e-315 970.0
CH2_k127_10180996_1 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 353.0
CH2_k127_1018110_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 1.262e-302 938.0
CH2_k127_1018110_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 1.105e-234 768.0
CH2_k127_1018110_2 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 575.0
CH2_k127_1018110_3 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 554.0
CH2_k127_1018110_4 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 465.0
CH2_k127_1018110_5 Voltage gated chloride channel - - - 0.0000000000000000000000000000006585 130.0
CH2_k127_10197608_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 359.0
CH2_k127_10234869_0 acyl-CoA dehydrogenase - - - 4.272e-255 803.0
CH2_k127_10234869_1 PFAM SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 464.0
CH2_k127_10234869_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000002538 102.0
CH2_k127_10234869_3 Peptidase, M16 - - - 0.0001782 52.0
CH2_k127_10246946_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1200.0
CH2_k127_10246946_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 0.0 1015.0
CH2_k127_10246946_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 541.0
CH2_k127_10246946_3 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000865 255.0
CH2_k127_10246946_4 Phosphate-selective porin O and P - - - 0.000000000000000000000000000000003261 139.0
CH2_k127_10249813_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 1.549e-209 661.0
CH2_k127_10249813_1 3-isopropylmalate dehydrogenase activity K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 464.0
CH2_k127_10249813_2 GTP binding K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 361.0
CH2_k127_10249813_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 317.0
CH2_k127_10290603_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 2.063e-285 892.0
CH2_k127_10290603_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.061e-276 858.0
CH2_k127_10290603_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 589.0
CH2_k127_10290603_4 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.000000218 64.0
CH2_k127_10290603_5 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0002876 54.0
CH2_k127_10341768_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 3.858e-205 642.0
CH2_k127_10341768_1 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 352.0
CH2_k127_10341768_2 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 299.0
CH2_k127_10341768_3 P-type atpase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000001117 190.0
CH2_k127_10347982_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.805e-242 763.0
CH2_k127_10347982_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 490.0
CH2_k127_10347982_2 Y_Y_Y domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 327.0
CH2_k127_10351955_0 AcrB/AcrD/AcrF family - - - 0.0 1340.0
CH2_k127_10351955_1 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 619.0
CH2_k127_10351955_2 peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 433.0
CH2_k127_10351955_3 Protein of unknown function (DUF2892) - - - 0.00000000000000000000006871 99.0
CH2_k127_10351955_4 Domain of unknown function DUF302 - - - 0.00000000000000000003604 99.0
CH2_k127_10351955_5 Protein of unknown function (DUF2892) - - - 0.000000000000000004994 91.0
CH2_k127_10375126_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1793.0
CH2_k127_10375126_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.748e-270 842.0
CH2_k127_10375126_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 430.0
CH2_k127_10375126_3 virulence factor MVIN family protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 423.0
CH2_k127_10375126_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000005339 155.0
CH2_k127_10375126_5 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.000000001615 66.0
CH2_k127_10377379_0 Carboxypeptidase regulatory-like domain - - - 1.773e-301 959.0
CH2_k127_10377379_1 SpoIVB peptidase S55 - - - 1.053e-255 800.0
CH2_k127_10377379_2 PFAM SMP-30 Gluconolaconase - - - 7.531e-246 769.0
CH2_k127_10391741_0 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 8.542e-272 846.0
CH2_k127_10391741_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000009347 211.0
CH2_k127_10391741_2 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000009059 192.0
CH2_k127_10391741_3 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000003007 83.0
CH2_k127_10405017_0 lipopolysaccharide metabolic process K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 595.0
CH2_k127_10405017_1 nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 508.0
CH2_k127_10405017_2 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 297.0
CH2_k127_10405017_3 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog)) - GO:0008150,GO:0040007 - 0.00000000000000000000000000000000000000003045 154.0
CH2_k127_10405017_4 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000001099 145.0
CH2_k127_1046577_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 1.084e-231 728.0
CH2_k127_1046577_1 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 493.0
CH2_k127_1046577_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 327.0
CH2_k127_10503637_0 TIGRFAM glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 5.157e-212 670.0
CH2_k127_10511712_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 369.0
CH2_k127_10511712_1 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000716 241.0
CH2_k127_10511712_2 phosphorelay signal transduction system K02477 - - 0.0000000000000000000000000000000000001952 148.0
CH2_k127_10537249_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 359.0
CH2_k127_10537249_1 chlorophyll binding - - - 0.000000000000000000000000000000000000000000000000000001892 202.0
CH2_k127_10537249_2 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0002582 46.0
CH2_k127_10549248_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 552.0
CH2_k127_10549248_1 PFAM Electron transfer flavoprotein alpha K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 404.0
CH2_k127_10549248_2 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 377.0
CH2_k127_10549248_3 COG0457 FOG TPR repeat - - - 0.00001864 51.0
CH2_k127_10564398_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1328.0
CH2_k127_10564398_1 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 612.0
CH2_k127_10564398_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 546.0
CH2_k127_10564398_3 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 479.0
CH2_k127_10564398_4 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000003848 196.0
CH2_k127_10564398_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000921 124.0
CH2_k127_1057351_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 9.937e-214 670.0
CH2_k127_1057351_1 Asparaginase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 440.0
CH2_k127_1057351_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 317.0
CH2_k127_1057351_3 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 332.0
CH2_k127_1057351_4 phosphorelay signal transduction system - - - 0.000000001482 61.0
CH2_k127_1057351_5 pfam abc K02032 - - 0.00000003876 55.0
CH2_k127_10622955_0 oligopeptide transporter, OPT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 570.0
CH2_k127_10622955_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 533.0
CH2_k127_10622955_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007338 270.0
CH2_k127_10622955_3 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002505 280.0
CH2_k127_10622955_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000002118 196.0
CH2_k127_10622955_5 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000002054 63.0
CH2_k127_10637662_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 555.0
CH2_k127_10637662_1 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 461.0
CH2_k127_10637662_2 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 335.0
CH2_k127_10644843_0 Phage Tail Collar Domain - - - 0.00000000000000000000000000000000000000000000000000000000003526 210.0
CH2_k127_10644843_1 Phage Tail Collar Domain - - - 0.00000000000000000000000000000000000000000000000000005184 192.0
CH2_k127_10644843_2 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000002872 170.0
CH2_k127_10644843_3 Periplasmic binding protein domain K01999 - - 0.0000000000000000000001664 110.0
CH2_k127_10647534_0 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 5.007e-215 681.0
CH2_k127_10647534_1 ABC nitrate sulphonate bicarbonate family transporter, ATPase subunit K02049 - - 3.639e-195 620.0
CH2_k127_10721732_0 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000008622 232.0
CH2_k127_10721732_1 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000001701 219.0
CH2_k127_10721732_2 WG containing repeat - - - 0.000000000000000000000000000000000000111 155.0
CH2_k127_10721732_3 Lysozyme inhibitor LprI - - - 0.00000000000004851 82.0
CH2_k127_10729093_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 519.0
CH2_k127_10729093_1 phosphorelay signal transduction system K02282,K02482,K03557,K04757 - 2.7.11.1,2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006887 383.0
CH2_k127_10729093_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003345 272.0
CH2_k127_10729093_3 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002707 258.0
CH2_k127_10729093_4 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000000000000002552 189.0
CH2_k127_10729093_5 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000002218 51.0
CH2_k127_10744269_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 7.482e-199 643.0
CH2_k127_10744269_1 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000001363 199.0
CH2_k127_10889889_0 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 2.181e-235 733.0
CH2_k127_10889889_1 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000004286 141.0
CH2_k127_10901837_0 Peptidase S46 - - - 2.983e-288 900.0
CH2_k127_10901837_1 Peptidase S46 - - - 1.959e-241 766.0
CH2_k127_10901837_2 Belongs to the TPP enzyme family K04103 - 4.1.1.74 4.06e-213 674.0
CH2_k127_10901837_3 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 347.0
CH2_k127_1090337_0 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000001146 133.0
CH2_k127_11015231_0 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000009008 154.0
CH2_k127_11015231_2 DNA-binding domain in plant proteins such as APETALA2 and EREBPs - - - 0.0001968 54.0
CH2_k127_11022591_0 glutamine synthetase K01915 - 6.3.1.2 1.152e-218 692.0
CH2_k127_11022591_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 499.0
CH2_k127_11022591_10 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000000000000004806 172.0
CH2_k127_11022591_11 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000004107 157.0
CH2_k127_11022591_12 nUDIX hydrolase - - - 0.000000000000000000000000000000000002644 139.0
CH2_k127_11022591_13 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000001692 136.0
CH2_k127_11022591_14 domain, Protein - - - 0.000000000000002823 85.0
CH2_k127_11022591_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 405.0
CH2_k127_11022591_3 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 371.0
CH2_k127_11022591_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 312.0
CH2_k127_11022591_5 arylamine N-acetyltransferase activity K00675 - 2.3.1.118 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 297.0
CH2_k127_11022591_6 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001132 248.0
CH2_k127_11022591_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000009885 239.0
CH2_k127_11022591_9 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000009052 236.0
CH2_k127_11027549_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 469.0
CH2_k127_11027549_1 TIGRFAM daunorubicin resistance ABC transporter ATP-binding subunit K01990 - - 0.000000000000000001409 85.0
CH2_k127_1112336_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.495e-276 853.0
CH2_k127_1112336_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001507 284.0
CH2_k127_11130454_0 PFAM ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 410.0
CH2_k127_11274664_0 Organic Anion Transporter Polypeptide (OATP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 503.0
CH2_k127_11274664_1 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000000000000000000001158 160.0
CH2_k127_11292598_0 Homoserine dehydrogenase K00928,K12524 - 1.1.1.3,2.7.2.4 7.357e-267 845.0
CH2_k127_11292598_1 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 364.0
CH2_k127_11292598_2 ADP transmembrane transporter activity K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 305.0
CH2_k127_11292598_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000513 250.0
CH2_k127_11343623_0 Class-II DAHP synthetase family K01626 - 2.5.1.54 1.812e-209 672.0
CH2_k127_11343623_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 543.0
CH2_k127_11343623_2 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 513.0
CH2_k127_11343623_3 Glutamine synthetase type III N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 376.0
CH2_k127_11343623_4 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 361.0
CH2_k127_11343623_5 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 311.0
CH2_k127_11343623_6 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000006199 118.0
CH2_k127_11365745_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 3.77e-278 871.0
CH2_k127_11365745_1 Belongs to the peptidase S11 family K07258,K07262 - 3.4.16.4 0.000000000000000000000000001094 115.0
CH2_k127_11412255_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 6.024e-266 831.0
CH2_k127_11412255_1 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 425.0
CH2_k127_11412255_2 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000624 272.0
CH2_k127_11412255_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000001127 165.0
CH2_k127_11415086_0 ABC transporter transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 522.0
CH2_k127_11415086_1 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 480.0
CH2_k127_11415736_0 PFAM BNR Asp-box repeat - - - 4.169e-250 800.0
CH2_k127_11415736_1 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 626.0
CH2_k127_11415736_2 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 552.0
CH2_k127_11415736_3 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000353 208.0
CH2_k127_11431068_0 AAA ATPase K07478 - - 3.058e-223 699.0
CH2_k127_11431068_1 von Willebrand factor (vWF) type A domain K11912 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 355.0
CH2_k127_11431068_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 286.0
CH2_k127_11431068_3 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000002402 213.0
CH2_k127_11431068_4 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000001081 174.0
CH2_k127_11453445_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 3.675e-195 616.0
CH2_k127_11453445_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 517.0
CH2_k127_11453445_2 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 431.0
CH2_k127_11453445_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 353.0
CH2_k127_11453445_4 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 329.0
CH2_k127_11453445_5 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000001077 176.0
CH2_k127_11453445_6 oligopeptide transporter, OPT family - - - 0.00000000000000000000000000000000000000000000009703 172.0
CH2_k127_11453445_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000004808 158.0
CH2_k127_11467570_0 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 9.928e-230 724.0
CH2_k127_11467570_1 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 477.0
CH2_k127_11467570_10 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000002574 209.0
CH2_k127_11467570_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009989 424.0
CH2_k127_11467570_3 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 383.0
CH2_k127_11467570_4 DNA ligase OB-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 338.0
CH2_k127_11467570_5 May be involved in recombination K03554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 312.0
CH2_k127_11467570_6 Uncharacterized ACR, COG1678 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004467 268.0
CH2_k127_11467570_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005016 248.0
CH2_k127_11467570_8 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002948 257.0
CH2_k127_11467570_9 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000001017 223.0
CH2_k127_11468514_0 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 563.0
CH2_k127_11468514_2 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 342.0
CH2_k127_11468514_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 324.0
CH2_k127_11468514_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 295.0
CH2_k127_11468514_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009312 268.0
CH2_k127_11476850_0 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009789 567.0
CH2_k127_11476850_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 473.0
CH2_k127_11476850_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001954 274.0
CH2_k127_11476850_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000003825 136.0
CH2_k127_11526591_0 alpha beta K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 396.0
CH2_k127_11526591_1 Peptidase family M28 - - - 0.0004742 44.0
CH2_k127_1153722_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.222e-216 677.0
CH2_k127_1153722_1 Histidine kinase - - - 0.000000000001049 77.0
CH2_k127_1153785_0 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 542.0
CH2_k127_1153785_1 PFAM nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 496.0
CH2_k127_11585194_0 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 487.0
CH2_k127_11585194_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 484.0
CH2_k127_11585194_2 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 351.0
CH2_k127_11585194_4 Type II/IV secretion system protein - - - 0.0000004944 52.0
CH2_k127_11587735_0 carbohydrate metabolic process K09798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007064 302.0
CH2_k127_11587735_1 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007872 243.0
CH2_k127_11587735_2 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000005586 239.0
CH2_k127_11604779_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 521.0
CH2_k127_11604779_1 [acyl-carrier-protein] S-malonyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 356.0
CH2_k127_11604779_2 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004492 252.0
CH2_k127_11604779_3 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000002913 61.0
CH2_k127_11604779_4 Glyoxalase bleomycin resistance protein dioxygenase superfamily protein 19 - - - 0.0001032 45.0
CH2_k127_11632425_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 542.0
CH2_k127_11632425_1 peptidase S45, penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 310.0
CH2_k127_11632425_2 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000001512 213.0
CH2_k127_11632425_3 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000001338 187.0
CH2_k127_11632425_4 ThiS family - - - 0.0000000000000000000000000000002815 125.0
CH2_k127_11632876_0 Required for chromosome condensation and partitioning K03529 - - 1.602e-230 729.0
CH2_k127_11632876_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000004275 229.0
CH2_k127_11640444_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 338.0
CH2_k127_11640444_1 - - - - 0.0000000000000000007206 89.0
CH2_k127_11645052_0 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 505.0
CH2_k127_11645052_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000002189 91.0
CH2_k127_11645052_2 OmpA family K03286 - - 0.000000003054 68.0
CH2_k127_11659669_0 Gaf domain K01768,K11527,K18967,K21009 - 2.7.13.3,2.7.7.65,4.6.1.1 0.000000000000000000000000000000000000000000000000000000002543 226.0
CH2_k127_11678045_0 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 452.0
CH2_k127_11678045_1 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 396.0
CH2_k127_11678045_2 N-acyl-L-amino acid amidohydrolase K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 317.0
CH2_k127_11678045_3 PFAM Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002221 269.0
CH2_k127_11678937_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 499.0
CH2_k127_11678937_1 DegT/DnrJ/EryC1/StrS aminotransferase family K02805 - 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 489.0
CH2_k127_11678937_2 O-acyltransferase activity K00661,K21379 - 2.3.1.209,2.3.1.79 0.00000000000000000000000000000000000000000000000000000000000000000004851 240.0
CH2_k127_11678937_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000004834 205.0
CH2_k127_11678937_4 PFAM Nucleotidyl transferase K15669 - 2.7.7.71 0.000000003662 60.0
CH2_k127_11723800_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 6.914e-250 781.0
CH2_k127_11723800_1 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000001809 168.0
CH2_k127_11728320_0 Type III restriction enzyme res subunit K10843 - 3.6.4.12 0.0 1075.0
CH2_k127_11728320_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009617 612.0
CH2_k127_11728320_2 lipoprotein localization to outer membrane K02004,K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000011 241.0
CH2_k127_11728320_3 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000009223 195.0
CH2_k127_11738439_0 cytochrome c - GO:0005575,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017004,GO:0022607,GO:0031224,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0065003,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 575.0
CH2_k127_11738439_1 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 374.0
CH2_k127_11738439_3 - - - - 0.000002041 51.0
CH2_k127_11745996_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 536.0
CH2_k127_11745996_1 CoA binding domain - - - 0.000000000000000000000000000000000000000000000002721 177.0
CH2_k127_11745996_2 - - - - 0.00000000000000000000000002397 119.0
CH2_k127_11802320_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1093.0
CH2_k127_11834378_0 PhoQ Sensor - - - 6.359e-201 655.0
CH2_k127_11834378_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 578.0
CH2_k127_11834378_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001043 274.0
CH2_k127_11834378_3 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000002458 231.0
CH2_k127_11834378_4 Arginine repressor, DNA binding domain K03402 - - 0.0000000000000000000000000000001809 128.0
CH2_k127_11834378_5 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00005047 47.0
CH2_k127_11844425_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.511e-210 661.0
CH2_k127_11844425_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 511.0
CH2_k127_11844425_2 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 395.0
CH2_k127_11844425_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 349.0
CH2_k127_11844425_5 diguanylate cyclase - - - 0.0000000000000000000000000000000000005461 145.0
CH2_k127_11844425_6 Peptidase S24-like - - - 0.0000000000000000000000000000000003237 134.0
CH2_k127_11872213_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1365.0
CH2_k127_11872213_1 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1131.0
CH2_k127_11872213_2 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 452.0
CH2_k127_11872213_3 - K00241 - - 0.000000000000000000000000000000000000000000000000000000000000001088 225.0
CH2_k127_11872213_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000002406 215.0
CH2_k127_11872213_5 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000001285 161.0
CH2_k127_11884804_0 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 422.0
CH2_k127_11884804_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 368.0
CH2_k127_11884804_2 desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 319.0
CH2_k127_11884804_3 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000006574 190.0
CH2_k127_11884804_4 - - - - 0.0000000000000000000000009538 111.0
CH2_k127_11896375_0 SMART Elongator protein 3 MiaB NifB - - - 5.667e-282 877.0
CH2_k127_11896375_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 5.739e-219 687.0
CH2_k127_11896375_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 576.0
CH2_k127_11896375_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 569.0
CH2_k127_11896375_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000003059 241.0
CH2_k127_11896375_5 Nicotinamide mononucleotide transporter K03811 - - 0.000000000000000000000000000000000000000000000000000000000000000005582 234.0
CH2_k127_11896375_6 ATPase kinase involved in NAD metabolism - - - 0.00000000000000000000000000000000000000005323 158.0
CH2_k127_119069_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 7.059e-292 904.0
CH2_k127_119069_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 361.0
CH2_k127_119069_10 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000000000000001573 154.0
CH2_k127_119069_11 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000008229 149.0
CH2_k127_119069_12 electron transfer activity K05337 - - 0.00000000000000000000000000000001414 127.0
CH2_k127_119069_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 355.0
CH2_k127_119069_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 328.0
CH2_k127_119069_4 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 306.0
CH2_k127_119069_5 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000000000002771 214.0
CH2_k127_119069_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000007059 215.0
CH2_k127_119069_7 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000000000000000000000000000000000000002838 210.0
CH2_k127_119069_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000007282 214.0
CH2_k127_11908866_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 2.054e-304 942.0
CH2_k127_11908866_1 alpha beta alpha domain I - - - 7.174e-263 819.0
CH2_k127_11908866_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 5.142e-209 668.0
CH2_k127_11908866_3 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07114 - - 0.0000000000000000000000000000000000000000000003036 173.0
CH2_k127_11913820_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1803.0
CH2_k127_11927374_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008757 494.0
CH2_k127_11927374_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008618 447.0
CH2_k127_11927374_2 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 393.0
CH2_k127_11956740_0 Carboxypeptidase regulatory-like domain - - - 0.0 1130.0
CH2_k127_11956740_1 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 320.0
CH2_k127_11956740_2 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001624 280.0
CH2_k127_11956740_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004062 260.0
CH2_k127_11968117_1 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000002455 169.0
CH2_k127_11979190_0 - K12065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 481.0
CH2_k127_11979190_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 307.0
CH2_k127_11979190_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009877 261.0
CH2_k127_11979190_3 Iron-storage protein K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000001826 235.0
CH2_k127_11979190_4 FMN binding K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000004652 195.0
CH2_k127_11979190_6 Calcineurin-like phosphoesterase K07098 - - 0.000000000000003968 79.0
CH2_k127_11979190_7 2Fe-2S -binding domain K02192 - - 0.0000000004153 63.0
CH2_k127_11982363_0 Zinc metalloprotease (Elastase) K08603,K20273 - 3.4.24.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 617.0
CH2_k127_11982363_1 Zinc metalloprotease (Elastase) K08603,K20273 - 3.4.24.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 582.0
CH2_k127_11982363_2 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000377 265.0
CH2_k127_11982363_5 Redoxin - - - 0.0000000000000000000000000000000000000000000273 168.0
CH2_k127_11982363_6 Bacterial regulatory protein, Fis family - - - 0.00000000000000000003784 90.0
CH2_k127_12009248_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1294.0
CH2_k127_12010465_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 382.0
CH2_k127_12010465_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000003707 216.0
CH2_k127_12031936_0 Heat shock 70 kDa protein K04043 - - 7.56e-321 990.0
CH2_k127_12031936_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009692 426.0
CH2_k127_12031936_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 388.0
CH2_k127_12031936_3 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000000000000000000002503 225.0
CH2_k127_12031936_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000000007634 222.0
CH2_k127_12068423_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 379.0
CH2_k127_12068423_1 - - - - 0.000000000006326 76.0
CH2_k127_12068423_2 Peptidase M16 inactive domain - - - 0.000001553 52.0
CH2_k127_12101064_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0017144,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046950,GO:0046951,GO:0050218,GO:0070013,GO:0071704,GO:1901568,GO:1901570,GO:1901576,GO:1902224 6.2.1.1,6.2.1.17 0.0 1136.0
CH2_k127_12101064_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 9.215e-301 927.0
CH2_k127_12101064_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000005362 213.0
CH2_k127_12101064_11 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000004725 166.0
CH2_k127_12101064_13 FOG HPt domain K20976 - - 0.00000009556 58.0
CH2_k127_12101064_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.071e-279 864.0
CH2_k127_12101064_3 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 412.0
CH2_k127_12101064_5 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 366.0
CH2_k127_12101064_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 357.0
CH2_k127_12101064_7 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.00000000000000000000000000000000000000000000000000000000000000001194 227.0
CH2_k127_12101064_8 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000005185 229.0
CH2_k127_12101064_9 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000004732 213.0
CH2_k127_12127387_0 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 548.0
CH2_k127_12127387_1 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 552.0
CH2_k127_12127387_2 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000002979 230.0
CH2_k127_12127387_3 PFAM peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000004826 233.0
CH2_k127_12129852_0 Protein of unknown function (DUF1579) - - - 0.00000000000001998 80.0
CH2_k127_12129852_1 - - - - 0.0003083 51.0
CH2_k127_12184026_0 Protein of unknown function, DUF255 K06888 - - 2.408e-300 937.0
CH2_k127_12184026_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 9.897e-220 694.0
CH2_k127_12184026_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 451.0
CH2_k127_12184026_3 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000001009 146.0
CH2_k127_12184026_5 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.00001219 52.0
CH2_k127_12224874_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 336.0
CH2_k127_12224874_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 295.0
CH2_k127_12224874_2 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001327 185.0
CH2_k127_12246620_0 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000752 224.0
CH2_k127_12246620_1 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000116 79.0
CH2_k127_12287798_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 3.027e-287 895.0
CH2_k127_12287798_2 1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31,5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000001029 229.0
CH2_k127_12336928_0 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 344.0
CH2_k127_12336928_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 329.0
CH2_k127_12336928_2 - - - - 0.00000000000000000000000000000000000000000000006932 180.0
CH2_k127_12343805_0 Protein tyrosine kinase K12132 - 2.7.11.1 8.519e-205 661.0
CH2_k127_12343805_1 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006871 274.0
CH2_k127_12343805_2 - - - - 0.0000000000000000000000001002 121.0
CH2_k127_12361442_0 PFAM Polysulphide reductase, NrfD - - - 3.289e-240 749.0
CH2_k127_12361442_1 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 485.0
CH2_k127_12361442_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 429.0
CH2_k127_12361442_3 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 342.0
CH2_k127_12361442_4 mttA/Hcf106 family K03116 - - 0.00000000000000009053 87.0
CH2_k127_12361442_6 methyl-accepting chemotaxis protein K03406,K07216 - - 0.00000005048 66.0
CH2_k127_12361442_7 Hemerythrin HHE cation binding domain - - - 0.000001304 58.0
CH2_k127_12373722_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 466.0
CH2_k127_12373722_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 327.0
CH2_k127_12373722_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000008005 120.0
CH2_k127_12373823_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000084 229.0
CH2_k127_12373823_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000004629 120.0
CH2_k127_12373887_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1030.0
CH2_k127_12373887_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.416e-249 780.0
CH2_k127_12373887_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 550.0
CH2_k127_12373887_3 ATP synthesis coupled electron transport K00340,K05576 - 1.6.5.3 0.0000000000000000000000000000000000000001143 153.0
CH2_k127_12373887_4 Belongs to the complex I subunit 6 family K00339 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.00000001249 57.0
CH2_k127_12401063_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.601e-273 847.0
CH2_k127_12401063_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000001952 192.0
CH2_k127_12401063_2 CBS domain - - - 0.0000000000000000000000000000000000000000000000000003043 189.0
CH2_k127_12401063_3 Uncharacterized conserved protein (DUF2164) - - - 0.000000000000000003452 91.0
CH2_k127_12401063_4 integral membrane protein - - - 0.00002173 54.0
CH2_k127_12432645_0 cAMP biosynthetic process K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 499.0
CH2_k127_12433875_0 Prolyl oligopeptidase family - - - 0.0 1080.0
CH2_k127_12433875_1 HD domain - - - 5.716e-220 691.0
CH2_k127_12433875_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 443.0
CH2_k127_12433875_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 456.0
CH2_k127_12433875_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 394.0
CH2_k127_12433875_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000002081 256.0
CH2_k127_12456779_0 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000005887 231.0
CH2_k127_12456779_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000003798 194.0
CH2_k127_12456779_2 - - - - 0.00000000000000000000000007913 113.0
CH2_k127_12514625_0 Peptidase dimerisation domain - - - 1.619e-207 656.0
CH2_k127_12514625_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 421.0
CH2_k127_12514625_2 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000001493 232.0
CH2_k127_12514625_3 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000009528 248.0
CH2_k127_12514625_4 Allomyces macrogynus ATCC 38327 - - - 0.000000000000000000000000000000000000000000000000000000000000000001805 234.0
CH2_k127_12516327_0 Leukotriene A4 hydrolase, C-terminal - - - 1.577e-211 677.0
CH2_k127_12516327_1 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 526.0
CH2_k127_12516327_2 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 426.0
CH2_k127_12516327_3 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008323 332.0
CH2_k127_12516327_4 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 323.0
CH2_k127_12516327_5 iron-sulfur cluster assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 283.0
CH2_k127_12516327_6 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000002883 229.0
CH2_k127_12516327_7 aminopeptidase - - - 0.000000000000000002183 100.0
CH2_k127_12533705_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1296.0
CH2_k127_12533705_1 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 467.0
CH2_k127_12533705_2 Ferredoxin K04755,K11107 - - 0.0000000000000000000000000000000000003124 155.0
CH2_k127_1254060_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 645.0
CH2_k127_1254060_1 Surface antigen variable number - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 579.0
CH2_k127_1254060_2 cellulase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002245 260.0
CH2_k127_12547538_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1314.0
CH2_k127_12547538_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.539e-227 712.0
CH2_k127_12547538_10 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008322 258.0
CH2_k127_12547538_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000000000000007357 235.0
CH2_k127_12547538_12 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000001176 233.0
CH2_k127_12547538_13 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000000000000000006009 227.0
CH2_k127_12547538_14 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000000000000002025 217.0
CH2_k127_12547538_15 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000008293 196.0
CH2_k127_12547538_16 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000000008899 191.0
CH2_k127_12547538_17 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000006568 175.0
CH2_k127_12547538_18 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000000003562 153.0
CH2_k127_12547538_19 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000000003095 140.0
CH2_k127_12547538_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 489.0
CH2_k127_12547538_20 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000001307 123.0
CH2_k127_12547538_21 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000009749 123.0
CH2_k127_12547538_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 385.0
CH2_k127_12547538_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 361.0
CH2_k127_12547538_5 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008139 349.0
CH2_k127_12547538_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 317.0
CH2_k127_12547538_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 296.0
CH2_k127_12547538_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004408 284.0
CH2_k127_12547538_9 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000709 273.0
CH2_k127_12564168_0 Domain of unknown function (DUF4139) - - - 4.059e-228 720.0
CH2_k127_12564168_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000007988 179.0
CH2_k127_12564168_2 - - - - 0.0000000000000000000000000000000000000001754 155.0
CH2_k127_1258160_0 PFAM Alcohol dehydrogenase K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 434.0
CH2_k127_1258160_1 Tetratricopeptide repeat - - - 0.00007921 54.0
CH2_k127_12617542_1 4 iron, 4 sulfur cluster binding K02573 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 301.0
CH2_k127_12630037_0 Sugar (and other) transporter - - - 1.365e-307 949.0
CH2_k127_12630037_1 AMP binding K16211 - - 3.298e-205 662.0
CH2_k127_12630037_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 298.0
CH2_k127_12630037_3 Ribosomal protein L17 K02879 - - 0.00000000000000000004027 90.0
CH2_k127_12630655_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.657e-218 685.0
CH2_k127_12630655_3 - - - - 0.0000000000000000000000000000000000001316 150.0
CH2_k127_12645248_0 positive regulation of isoprenoid metabolic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009893,GO:0009987,GO:0019216,GO:0019222,GO:0019747,GO:0031323,GO:0031325,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045828,GO:0045834,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0065007,GO:0071704,GO:0080090,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 340.0
CH2_k127_12645248_2 Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate - - - 0.00004956 48.0
CH2_k127_1266229_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 371.0
CH2_k127_1266229_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004373 284.0
CH2_k127_1266229_2 ankyrin repeat - - - 0.00000000000000001064 94.0
CH2_k127_1268041_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1108.0
CH2_k127_1268041_1 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 3.278e-206 657.0
CH2_k127_1268041_2 Malate synthase K01638 - 2.3.3.9 7.732e-195 622.0
CH2_k127_1268041_3 Pfam:DUF955 K07110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 460.0
CH2_k127_1268041_4 nUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 307.0
CH2_k127_12684658_0 Pyridoxal-phosphate dependent enzyme K01738,K01912 - 2.5.1.47,6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 331.0
CH2_k127_12684658_1 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000619 134.0
CH2_k127_12718870_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 324.0
CH2_k127_12718870_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 310.0
CH2_k127_12753148_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 533.0
CH2_k127_12753148_1 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00003554 49.0
CH2_k127_12753148_2 CDP-alcohol phosphatidyltransferase - - - 0.000683 47.0
CH2_k127_12755582_0 - - - - 0.00000000000000000000000000000000000000000000000000002846 197.0
CH2_k127_12755582_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000003419 177.0
CH2_k127_12755582_2 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000002495 139.0
CH2_k127_12755648_0 cobalamin binding K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1758.0
CH2_k127_12878144_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.74e-229 719.0
CH2_k127_12878144_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 475.0
CH2_k127_12878144_2 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 347.0
CH2_k127_12878144_3 Transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 327.0
CH2_k127_12878144_4 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000002909 198.0
CH2_k127_12881142_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 310.0
CH2_k127_12881142_1 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 297.0
CH2_k127_128996_0 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 475.0
CH2_k127_128996_1 peptidase activity K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000373 233.0
CH2_k127_128996_3 acetyltransferase - - - 0.0000000000000000000000000000000001313 137.0
CH2_k127_128996_4 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000009697 87.0
CH2_k127_12926415_0 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 313.0
CH2_k127_12926415_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 309.0
CH2_k127_12946034_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 440.0
CH2_k127_12946034_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 375.0
CH2_k127_12946034_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000006187 89.0
CH2_k127_12947754_0 DNA topoisomerase type I activity K03169 - 5.99.1.2 6.34e-196 631.0
CH2_k127_12965427_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 513.0
CH2_k127_12965427_1 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 475.0
CH2_k127_12966654_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 492.0
CH2_k127_12966654_1 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 310.0
CH2_k127_12966654_3 Thermolysin metallopeptidase, alpha-helical domain - - - 0.0000000001904 65.0
CH2_k127_12968657_0 synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 406.0
CH2_k127_12968657_1 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 376.0
CH2_k127_12968657_10 epimerase dehydratase K07071 - - 0.00000000000000000000000000000000000002634 151.0
CH2_k127_12968657_11 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000163 155.0
CH2_k127_12968657_12 - - - - 0.0000000000000000000000000000000000249 150.0
CH2_k127_12968657_13 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000001536 120.0
CH2_k127_12968657_14 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.0000000000000000000001575 101.0
CH2_k127_12968657_15 Protein of unknown function (DUF1475) - - - 0.000002056 53.0
CH2_k127_12968657_16 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.0001315 44.0
CH2_k127_12968657_2 amine oxidase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 373.0
CH2_k127_12968657_3 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 317.0
CH2_k127_12968657_4 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002233 274.0
CH2_k127_12968657_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002439 255.0
CH2_k127_12968657_6 Outer Membrane Lipoprotein K03098 - - 0.00000000000000000000000000000000000000000000000000000000000000000008578 239.0
CH2_k127_12968657_7 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000001446 201.0
CH2_k127_12968657_8 Domain of unknown function (DUF4397) - - - 0.0000000000000000000000000000000000000000000003107 180.0
CH2_k127_12968657_9 B12 binding domain K22491 - - 0.000000000000000000000000000000000000005325 158.0
CH2_k127_12974523_0 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000002111 233.0
CH2_k127_12974523_1 - - - - 0.00000000000000000000000000000000000001621 146.0
CH2_k127_12974523_2 Protein of unknown function (DUF2997) - - - 0.00000000835 61.0
CH2_k127_12974523_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00004626 46.0
CH2_k127_12980867_0 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 519.0
CH2_k127_12980867_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000002664 186.0
CH2_k127_12988393_0 May be involved in recombination K03554 - - 0.000000000000000000000000000000000000000000000000000000000000000001985 241.0
CH2_k127_12988393_1 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000007337 201.0
CH2_k127_12988393_2 - - - - 0.000000000000000000000000000000000000002909 161.0
CH2_k127_13036059_0 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 531.0
CH2_k127_13036059_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 460.0
CH2_k127_13036059_2 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 360.0
CH2_k127_13036059_3 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000001171 210.0
CH2_k127_130444_0 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 558.0
CH2_k127_130444_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 535.0
CH2_k127_130444_2 Permease, YjgP YjgQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009481 447.0
CH2_k127_130444_3 Pyridoxal phosphate biosynthetic protein PdxA K22024 - 1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000005372 220.0
CH2_k127_130444_4 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000004841 216.0
CH2_k127_130444_5 Hfq protein - - - 0.000000000000000000000000000000000000000000000000000000005163 220.0
CH2_k127_130444_6 4 iron, 4 sulfur cluster binding K02574 - - 0.0000000000000000000001324 108.0
CH2_k127_130444_7 - - - - 0.0000000003144 63.0
CH2_k127_13056292_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 2.542e-196 627.0
CH2_k127_13056292_1 FAD linked oxidase domain protein K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 438.0
CH2_k127_13060486_0 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002124 291.0
CH2_k127_13060486_1 CoA-binding domain protein - - - 0.000000000000000000000000000000000000000000000009969 179.0
CH2_k127_13060486_2 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000001726 181.0
CH2_k127_13060486_3 Domain of unknown function (DUF4349) - - - 0.0001362 52.0
CH2_k127_13065929_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1637.0
CH2_k127_13065929_1 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03466,K03657,K03684,K03724 - 3.1.13.5,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 449.0
CH2_k127_13065929_2 Protein of unknown function (DUF938) - - - 0.00000000000000000000000000000000000000001261 162.0
CH2_k127_13065929_3 membrane - - - 0.0000000000000000000000000000004281 137.0
CH2_k127_13065929_4 Protein of unknown function, DUF393 - - - 0.0000000007917 63.0
CH2_k127_1311652_0 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB - - - 0.000000000000000000000000000000000000000000000000000000000000005387 231.0
CH2_k127_1313906_0 GNAT family acetyltransferase K03802 - 6.3.2.29,6.3.2.30 0.0 1613.0
CH2_k127_1313906_1 Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation K01305 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008270,GO:0008798,GO:0016787,GO:0019538,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 547.0
CH2_k127_1313906_2 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 419.0
CH2_k127_1313906_3 Beta-lactamase - - - 0.00000000000000000000000000000000001634 147.0
CH2_k127_1313906_4 Mur ligase family, glutamate ligase domain - - - 0.0001133 44.0
CH2_k127_1324738_0 MoaE protein K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000004036 181.0
CH2_k127_1324738_2 RNase H K03469 - 3.1.26.4 0.0000000000000000000000000000000007039 140.0
CH2_k127_1324738_3 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.000000313 55.0
CH2_k127_1328172_0 Peptidase A24A, prepilin type IV K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 431.0
CH2_k127_1328172_1 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006324 247.0
CH2_k127_1328172_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000158 138.0
CH2_k127_1350857_0 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006302 274.0
CH2_k127_1350857_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001124 274.0
CH2_k127_1371901_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 355.0
CH2_k127_1371901_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000001424 96.0
CH2_k127_1386518_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.6e-226 707.0
CH2_k127_1386518_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 328.0
CH2_k127_1386518_2 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000009309 209.0
CH2_k127_1386518_4 Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine K00641 - 2.3.1.31 0.00000000000006257 85.0
CH2_k127_1427079_0 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 334.0
CH2_k127_1427079_1 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 303.0
CH2_k127_1427079_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000001301 214.0
CH2_k127_1427079_3 Protein of unknown function (DUF1211) - - - 0.0000000000002775 83.0
CH2_k127_1445494_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 520.0
CH2_k127_1445494_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000002051 205.0
CH2_k127_1445494_2 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000000003325 195.0
CH2_k127_1477742_0 asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 447.0
CH2_k127_1477742_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 336.0
CH2_k127_1477742_2 rRNA (uridine-N3-)-methyltransferase activity K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 314.0
CH2_k127_1477742_3 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000001313 179.0
CH2_k127_1477742_4 positive regulation of type IV pilus biogenesis K07343 - - 0.0000000000000000000000000000001784 127.0
CH2_k127_152195_0 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 541.0
CH2_k127_152195_1 Beta-lactamase - - - 0.0000000000000000000002995 98.0
CH2_k127_152326_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 509.0
CH2_k127_152326_1 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001048 261.0
CH2_k127_152326_2 - - - - 0.00000000000000001087 89.0
CH2_k127_1531114_0 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003331 278.0
CH2_k127_1531114_1 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000007271 245.0
CH2_k127_1531114_2 PFAM Alcohol dehydrogenase K13979 - - 0.0000000000000000000000000000000000000000000000002106 193.0
CH2_k127_1531114_3 Domain of unknown function (DUF5117) - - - 0.00000000006121 68.0
CH2_k127_1535656_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 6.137e-287 918.0
CH2_k127_1535656_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 7.189e-223 698.0
CH2_k127_1535656_2 Belongs to the transketolase family K00615 - 2.2.1.1 8.369e-209 658.0
CH2_k127_1535656_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000003178 260.0
CH2_k127_1535656_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000007419 191.0
CH2_k127_1535656_5 Ribosomal protein S20 K02968 - - 0.0000000000000000000000000001717 118.0
CH2_k127_154308_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 558.0
CH2_k127_154308_1 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 411.0
CH2_k127_154308_2 mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 381.0
CH2_k127_154308_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000002471 225.0
CH2_k127_154308_4 Amidohydrolase family - - - 0.0000000000000000000000001656 109.0
CH2_k127_1544265_0 Ferrous iron transport protein B K04759 - - 0.0 1045.0
CH2_k127_1544265_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 4.853e-224 700.0
CH2_k127_1544265_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 385.0
CH2_k127_1544265_3 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 318.0
CH2_k127_1544265_4 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000001585 245.0
CH2_k127_1544265_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000000000000000000001416 216.0
CH2_k127_1544265_6 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000001821 199.0
CH2_k127_1544265_7 iron ion homeostasis K03711,K04758 - - 0.0000000000000000000000006736 106.0
CH2_k127_1620206_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 426.0
CH2_k127_1620206_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002709 274.0
CH2_k127_1620206_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000001895 237.0
CH2_k127_1620206_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0002477 48.0
CH2_k127_1661615_0 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000008711 249.0
CH2_k127_1661615_1 Protein of unknown function, DUF255 - - - 0.0000000000000001793 90.0
CH2_k127_1661615_2 Rhodanese Homology Domain - - - 0.0000000000000002405 82.0
CH2_k127_1747816_0 Insulinase (Peptidase family M16) K07263 - - 1.145e-261 837.0
CH2_k127_1747816_1 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 492.0
CH2_k127_1747816_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 340.0
CH2_k127_1747816_3 kinase activity K02527,K11211 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15,2.7.1.166 0.0000000000000000000000000000000000000000000000000000000000000000009411 241.0
CH2_k127_1747816_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000001298 237.0
CH2_k127_1747816_5 of the PP-loop superfamily K06864 - - 0.00000000000000000000000000000000000000000000000009519 195.0
CH2_k127_1747816_7 Sterol carrier protein - - - 0.00000000000000000000000000000004912 129.0
CH2_k127_1747816_8 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000004509 76.0
CH2_k127_1775958_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.0 1901.0
CH2_k127_1775958_1 Pyridoxal-dependent decarboxylase conserved domain K22330 - 4.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 334.0
CH2_k127_1775958_2 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 298.0
CH2_k127_1775958_3 YwiC-like protein - - - 0.000000009088 59.0
CH2_k127_1804123_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000002262 142.0
CH2_k127_1847456_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0 1037.0
CH2_k127_1847456_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 3.455e-273 885.0
CH2_k127_1847456_12 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000002249 146.0
CH2_k127_1847456_13 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000005042 133.0
CH2_k127_1847456_14 membrane K08978 - - 0.00000000000000000000006032 106.0
CH2_k127_1847456_16 Putative phosphatase (DUF442) - - - 0.000000000000000004832 91.0
CH2_k127_1847456_2 Winged helix DNA-binding domain K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 537.0
CH2_k127_1847456_3 PFAM Phosphoadenosine phosphosulfate reductase K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 480.0
CH2_k127_1847456_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 476.0
CH2_k127_1847456_5 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 481.0
CH2_k127_1847456_6 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 404.0
CH2_k127_1847456_7 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 338.0
CH2_k127_1847456_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 327.0
CH2_k127_1847456_9 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000001405 212.0
CH2_k127_1857163_0 HELICc2 K03722 - 3.6.4.12 0.0 1024.0
CH2_k127_1857163_1 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 364.0
CH2_k127_1857163_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 288.0
CH2_k127_1858555_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0 1126.0
CH2_k127_1858555_1 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 389.0
CH2_k127_1858555_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000201 259.0
CH2_k127_186847_0 - - - - 0.0000000000000000001713 105.0
CH2_k127_186847_2 Domain of unknown function (DUF4262) - - - 0.000000000000001986 85.0
CH2_k127_186847_4 - - - - 0.0002615 48.0
CH2_k127_1877875_0 signal transduction histidine kinase - - - 2.943e-234 743.0
CH2_k127_1877875_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000609 501.0
CH2_k127_1877875_2 tRNA threonylcarbamoyladenosine modification K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000001982 211.0
CH2_k127_1877875_3 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000002382 124.0
CH2_k127_1877875_4 Protein conserved in bacteria - - - 0.000000000000000006559 99.0
CH2_k127_1910890_0 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K01782,K01825 GO:0003674,GO:0003824,GO:0003857,GO:0004165,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 1.108e-250 786.0
CH2_k127_1953500_0 - - - - 0.000000000000000000000001282 118.0
CH2_k127_1957837_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 570.0
CH2_k127_1957837_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 437.0
CH2_k127_1957837_2 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 396.0
CH2_k127_1957837_3 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000000000000000000000000000000014 237.0
CH2_k127_1957837_4 Acyltransferase family K11941 - - 0.0000000000000000000000000000000000000000000000003079 192.0
CH2_k127_1957837_5 PFAM NAD dependent epimerase dehydratase family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000001717 69.0
CH2_k127_1988240_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 516.0
CH2_k127_1988240_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 383.0
CH2_k127_2003610_0 Class-II DAHP synthetase family K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 582.0
CH2_k127_2010891_0 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 2.863e-291 907.0
CH2_k127_2010891_1 Spermine/spermidine synthase domain K00797 - 2.5.1.16 1.112e-230 724.0
CH2_k127_2010891_2 Domain of unknown function (DUF4178) - - - 4.279e-230 734.0
CH2_k127_2010891_3 PFAM Polyphosphate kinase 2 - - - 0.000000000000000000000000000000000000000000000000000000009162 202.0
CH2_k127_2045605_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 509.0
CH2_k127_2045605_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 366.0
CH2_k127_2045605_2 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002116 241.0
CH2_k127_2045605_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000005878 228.0
CH2_k127_2045605_4 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000000000000000000000003595 210.0
CH2_k127_2045605_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000003017 187.0
CH2_k127_2045605_6 Winged helix DNA-binding domain - - - 0.0000000000000000002596 99.0
CH2_k127_207270_0 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 327.0
CH2_k127_207270_1 translation release factor activity K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000000000000000001492 145.0
CH2_k127_207270_2 - - - - 0.0000002637 54.0
CH2_k127_2094004_0 Amidohydrolase family K01487 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008892,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0016814,GO:0018756,GO:0019239,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0046098,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 359.0
CH2_k127_2094004_1 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000004478 231.0
CH2_k127_2139851_0 Peptidase M64 N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 545.0
CH2_k127_2139851_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 363.0
CH2_k127_2139851_2 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006903 277.0
CH2_k127_2139851_3 nitric oxide dioxygenase activity - - - 0.000000000000000000000000007624 118.0
CH2_k127_2148921_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 8.316e-245 767.0
CH2_k127_2148921_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.561e-213 672.0
CH2_k127_2148921_2 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 342.0
CH2_k127_2148921_3 RDD family - - - 0.000000000000000000000000000000000000000000000000002374 187.0
CH2_k127_2148921_4 - - - - 0.00000000000000000000001097 106.0
CH2_k127_2148921_6 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000001574 75.0
CH2_k127_2148921_7 Protein of unknown function (DUF2752) - - - 0.0000000001314 67.0
CH2_k127_2148921_8 PBS lyase HEAT-like repeat - - - 0.0000001472 59.0
CH2_k127_215860_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 581.0
CH2_k127_215860_1 PFAM aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009911 492.0
CH2_k127_215860_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 433.0
CH2_k127_215860_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 406.0
CH2_k127_215860_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 394.0
CH2_k127_215860_5 Belongs to the DapB family K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000005748 260.0
CH2_k127_2169044_0 - - - - 0.0000000000000000000000000000003809 128.0
CH2_k127_2169044_1 tyrosine recombinase K04763 - - 0.0000000000000000000000000000004636 134.0
CH2_k127_2169044_2 nuclease activity K06218 - - 0.000000000000000000001242 98.0
CH2_k127_2169044_3 - - - - 0.0000000000000000007736 92.0
CH2_k127_2169044_4 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000002171 76.0
CH2_k127_2169044_5 DNA-binding helix-turn-helix protein - - - 0.00000004783 61.0
CH2_k127_2171268_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 9.048e-225 705.0
CH2_k127_2171268_1 Peptidogalycan biosysnthesis/recognition K00652 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000646 285.0
CH2_k127_2171268_2 protein-disulfide reductase activity K01829,K04084 - 1.8.1.8,5.3.4.1 0.000000000000000000000000000000000000000000000739 187.0
CH2_k127_2171268_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000001094 68.0
CH2_k127_2171268_4 exo-alpha-(2->6)-sialidase activity - - - 0.0009059 51.0
CH2_k127_218063_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 577.0
CH2_k127_218063_1 Histidine kinase internal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 382.0
CH2_k127_218063_2 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 360.0
CH2_k127_218063_3 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000001056 223.0
CH2_k127_218063_5 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.0000000000000000000000000000001732 137.0
CH2_k127_218063_7 Hemolysin secretion protein D K01993 - - 0.0000000242 65.0
CH2_k127_2192998_0 Cupin 2, conserved barrel domain protein K19547 - 5.3.3.19 0.000000000000000000000000000000000000000000000000000003805 205.0
CH2_k127_2192998_1 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000002946 183.0
CH2_k127_2192998_2 pkhd-type hydroxylase K00472,K07336 GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0033554,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0098771 1.14.11.2 0.0000000000000000000000000000000000000000003148 176.0
CH2_k127_2197448_0 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001722 285.0
CH2_k127_2197448_1 Protein of unknown function (DUF2804) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003378 293.0
CH2_k127_2197448_2 Esterase K03928 - 3.1.1.1 0.000000000000000000000000000000000000000000000000000000000006379 218.0
CH2_k127_2197448_3 transcriptional regulator K07109 - - 0.000000000000000000000000000000003624 145.0
CH2_k127_2197448_4 Belongs to the 5'-nucleotidase family K01081,K11751 - 3.1.3.5,3.6.1.45 0.000000000000000000000000001733 129.0
CH2_k127_2197448_5 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000002096 108.0
CH2_k127_2197448_6 GntR family K03710 - - 0.000000000000000000516 96.0
CH2_k127_2197448_7 long-chain fatty acid transport protein K06076 - - 0.0000000000000005096 92.0
CH2_k127_2219709_0 Domain of unknown function (DUF5118) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 566.0
CH2_k127_2266463_0 Transcriptional regulator K03603,K05799 - - 3.649e-312 975.0
CH2_k127_2307040_0 SNF2 Helicase protein - - - 0.0 1261.0
CH2_k127_2307040_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 376.0
CH2_k127_2307040_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000004427 237.0
CH2_k127_2307040_3 response regulator receiver - - - 0.000000000002678 70.0
CH2_k127_2308471_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756,K01857 - 4.3.2.2,5.5.1.2 1.995e-263 817.0
CH2_k127_2308471_1 Family membership K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000005013 194.0
CH2_k127_2315680_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 1.191e-246 776.0
CH2_k127_2315680_1 Arginosuccinate synthase K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 579.0
CH2_k127_2315680_10 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 377.0
CH2_k127_2315680_11 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000001369 173.0
CH2_k127_2315680_12 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000001373 139.0
CH2_k127_2315680_2 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 560.0
CH2_k127_2315680_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 545.0
CH2_k127_2315680_4 Domain of unknown function (DUF1611_C) P-loop domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 479.0
CH2_k127_2315680_5 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 424.0
CH2_k127_2315680_6 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 436.0
CH2_k127_2315680_7 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000772 411.0
CH2_k127_2315680_8 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 402.0
CH2_k127_2315680_9 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 392.0
CH2_k127_2336304_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 4.834e-219 686.0
CH2_k127_239285_0 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 1.587e-202 640.0
CH2_k127_239285_1 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000007095 267.0
CH2_k127_239285_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000001055 199.0
CH2_k127_239285_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000003936 156.0
CH2_k127_2413929_0 Conserved hypothetical protein 698 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 327.0
CH2_k127_2413929_1 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 323.0
CH2_k127_2413929_2 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000003736 256.0
CH2_k127_2413929_3 phosphorelay sensor kinase activity K02478,K07315,K07704 - 2.7.13.3,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000005023 241.0
CH2_k127_2413929_4 phosphorelay signal transduction system K02477 - - 0.0000000000000000000000000000000000003232 157.0
CH2_k127_2413929_5 Cysteine dioxygenase type I K00456 - 1.13.11.20 0.0000000000000000000000001504 113.0
CH2_k127_2413929_6 - - - - 0.00000000009596 69.0
CH2_k127_2452766_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1069.0
CH2_k127_2452766_1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 594.0
CH2_k127_2452766_2 Type II secretion system protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000001428 199.0
CH2_k127_2452766_3 DinB family - - - 0.000000000000000000000000000000000002184 151.0
CH2_k127_2493261_0 Class II release factor RF3, C-terminal domain - - - 1.674e-317 975.0
CH2_k127_2493261_1 PFAM peptidase S9A prolyl oligopeptidase domain protein beta-propeller K01354 - 3.4.21.83 3.943e-223 713.0
CH2_k127_2493261_2 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 598.0
CH2_k127_2493261_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 323.0
CH2_k127_2493261_4 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 287.0
CH2_k127_2503415_0 PFAM lipopolysaccharide biosynthesis K08252,K16554 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 452.0
CH2_k127_2503415_1 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002475 283.0
CH2_k127_2503415_2 Glycosyltransferase like family 2 K13002 - - 0.0000001715 53.0
CH2_k127_2527377_0 Prokaryotic cytochrome b561 - - - 3.259e-199 629.0
CH2_k127_2527377_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 418.0
CH2_k127_2527377_2 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 399.0
CH2_k127_2527377_4 SMART Resolvase, RNase H domain protein fold K06959 - - 0.0009222 42.0
CH2_k127_2531036_0 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 7.056e-198 629.0
CH2_k127_2552621_0 peptidase S9B dipeptidylpeptidase IV domain protein K01278 - 3.4.14.5 1.04e-216 689.0
CH2_k127_2552621_1 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 576.0
CH2_k127_2552621_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 433.0
CH2_k127_2552621_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 378.0
CH2_k127_2552621_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000003922 238.0
CH2_k127_2552621_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000008097 174.0
CH2_k127_2552621_6 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611,K07057 - 2.5.1.128,2.5.1.16,4.1.1.50 0.000000000000000000000000000000000006352 140.0
CH2_k127_2552621_7 membrane K09790 - - 0.000000000000000000000000007155 119.0
CH2_k127_2552621_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000006433 93.0
CH2_k127_2576132_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 603.0
CH2_k127_2576132_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 309.0
CH2_k127_2576132_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 299.0
CH2_k127_259644_0 Sortilin, neurotensin receptor 3, - - - 1.649e-198 630.0
CH2_k127_260205_0 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 599.0
CH2_k127_260205_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 459.0
CH2_k127_260205_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 463.0
CH2_k127_2622453_0 Elongator protein 3, MiaB family, Radical SAM K06937 - - 1.012e-239 747.0
CH2_k127_2622453_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.124e-227 710.0
CH2_k127_2622453_11 HEPN domain - - - 0.00000000000000007819 85.0
CH2_k127_2622453_12 salt-induced outer membrane protein K07283 - - 0.00003671 55.0
CH2_k127_2622453_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 1.519e-211 661.0
CH2_k127_2622453_3 PFAM aminotransferase class V K04487 GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 461.0
CH2_k127_2622453_4 5'-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 424.0
CH2_k127_2622453_5 PP-loop family K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 430.0
CH2_k127_2622453_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001438 252.0
CH2_k127_2622453_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001633 248.0
CH2_k127_2622453_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000002777 141.0
CH2_k127_2622453_9 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000007578 132.0
CH2_k127_2687265_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 587.0
CH2_k127_2687265_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 536.0
CH2_k127_2687265_2 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 325.0
CH2_k127_2687265_3 Belongs to the glycosyl hydrolase family 6 K01179 - 3.2.1.4 0.00000000000000000000000000000000000000001716 160.0
CH2_k127_2687265_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000006366 145.0
CH2_k127_26975_0 Oligopeptide transporter OPT - - - 1.847e-291 911.0
CH2_k127_26975_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 320.0
CH2_k127_26975_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000004777 235.0
CH2_k127_2716516_0 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008942 281.0
CH2_k127_2716516_1 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000007773 121.0
CH2_k127_2744421_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 7.529e-210 660.0
CH2_k127_2744421_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 481.0
CH2_k127_2744421_2 Sec-independent protein translocase protein (TatC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 346.0
CH2_k127_2744421_3 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 286.0
CH2_k127_2744421_4 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000004537 236.0
CH2_k127_2744421_5 - - - - 0.0000000000000000000000000000000000009139 142.0
CH2_k127_2744421_6 mttA/Hcf106 family K03116 - - 0.00000000000000000000006871 99.0
CH2_k127_2744421_7 - - - - 0.00000000000000008739 86.0
CH2_k127_2847768_0 PFAM binding-protein-dependent transport systems inner membrane component K02026,K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 443.0
CH2_k127_2847768_1 transmembrane transport K02025,K05814,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 384.0
CH2_k127_2847768_2 Bacterial extracellular solute-binding protein K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006118 276.0
CH2_k127_2854689_0 Sugar (and other) transporter K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 559.0
CH2_k127_2854689_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 497.0
CH2_k127_2854689_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 475.0
CH2_k127_2854689_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 449.0
CH2_k127_2854689_4 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 421.0
CH2_k127_2854689_5 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002293 267.0
CH2_k127_2883454_0 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 356.0
CH2_k127_2899502_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 401.0
CH2_k127_2904498_0 glycosyl transferase - - - 8.181e-203 641.0
CH2_k127_2904498_1 Sortilin, neurotensin receptor 3, - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004492 252.0
CH2_k127_2904498_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000009118 235.0
CH2_k127_2904498_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000002723 203.0
CH2_k127_2904498_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000001473 190.0
CH2_k127_2904498_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000002605 74.0
CH2_k127_2913384_0 Staphylococcal nuclease homologues - - - 0.000000000000000000000000000000000000000003658 159.0
CH2_k127_2913384_1 phosphohydrolase - - - 0.000000000000000000000000000000000000001143 154.0
CH2_k127_2913384_2 - - - - 0.000000000000008309 80.0
CH2_k127_2913384_4 Protein of unknown function DUF45 K07043 - - 0.0000004619 61.0
CH2_k127_2958676_0 PFAM Metal-dependent phosphohydrolase, HD K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002789 274.0
CH2_k127_2958676_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000003851 162.0
CH2_k127_2958676_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.00000000000000000000000000006074 130.0
CH2_k127_2958676_4 cell redox homeostasis K00384,K03671 - 1.8.1.9 0.00000000000000002269 91.0
CH2_k127_2958676_5 PFAM Polysaccharide deacetylase - - - 0.00000000000000004348 85.0
CH2_k127_2975630_0 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 507.0
CH2_k127_2975630_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 350.0
CH2_k127_2975630_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008494 290.0
CH2_k127_2975630_3 ADP transmembrane transporter activity K03301 - - 0.0000000000000000000000000000000000000000000000000000000000004365 214.0
CH2_k127_2975630_4 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000000000000000000000002774 198.0
CH2_k127_2975630_5 domain, Protein K01179 - 3.2.1.4 0.00000000000000004025 96.0
CH2_k127_2975630_6 NAD dependent epimerase/dehydratase family - - - 0.00000000007173 74.0
CH2_k127_2997951_0 Fumarase C C-terminus K01744 - 4.3.1.1 9.283e-294 905.0
CH2_k127_2997951_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 454.0
CH2_k127_2997951_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.000000000000000000000000000000000042 136.0
CH2_k127_2997951_3 Belongs to the ClpA ClpB family K03696 - - 0.0000000000000000000000000000003538 128.0
CH2_k127_2997951_4 Protein tyrosine kinase - - - 0.0000001546 62.0
CH2_k127_3008421_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.322e-253 788.0
CH2_k127_3008421_1 PFAM TonB-dependent Receptor - - - 1.23e-249 786.0
CH2_k127_3008421_2 MacB-like periplasmic core domain K02004 - - 3.325e-198 624.0
CH2_k127_3008421_3 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 511.0
CH2_k127_3008421_4 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 487.0
CH2_k127_3008421_5 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 322.0
CH2_k127_3008421_6 PFAM thioesterase superfamily K07107 - - 0.000000000000000000000000000000000000000000000001471 177.0
CH2_k127_3033458_0 hydroxymethylglutaryl-CoA reductase (NADPH) activity K00021 - 1.1.1.34 1.053e-206 654.0
CH2_k127_3033458_1 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 504.0
CH2_k127_3033458_2 esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 366.0
CH2_k127_3033458_3 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007633 286.0
CH2_k127_3033458_4 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000005619 256.0
CH2_k127_3033458_5 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.0000000000000001059 87.0
CH2_k127_3033458_6 PFAM PHA accumulation regulator DNA-binding protein - - - 0.000000000000003096 82.0
CH2_k127_3034637_0 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 1.957e-250 775.0
CH2_k127_3034637_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 441.0
CH2_k127_3034637_2 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 304.0
CH2_k127_3034637_3 Redoxin K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000003595 259.0
CH2_k127_3034637_4 deaminated base DNA N-glycosylase activity K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000003001 174.0
CH2_k127_3041393_0 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000007205 246.0
CH2_k127_3041393_1 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000002516 151.0
CH2_k127_3089267_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 1.028e-222 695.0
CH2_k127_3089267_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000002334 216.0
CH2_k127_309522_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 386.0
CH2_k127_309522_1 LVIVD repeat - - - 0.0007889 49.0
CH2_k127_3096_0 PFAM Peptidase M16 K07263 - - 4.882e-313 985.0
CH2_k127_3096_1 Predicted Permease Membrane Region K07085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 624.0
CH2_k127_3096_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 462.0
CH2_k127_3096_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 392.0
CH2_k127_3096_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000634 156.0
CH2_k127_3096_5 Tetratricopeptide repeat - - - 0.000005303 57.0
CH2_k127_3127711_0 growth of symbiont in host cell K07003 - - 0.0 1050.0
CH2_k127_3127711_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000002178 150.0
CH2_k127_3131589_0 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000009246 185.0
CH2_k127_3159843_0 Carboxypeptidase regulatory-like domain - - - 2.488e-234 765.0
CH2_k127_3159843_1 PFAM Protein kinase domain - - - 0.000000000000000000000000000000003261 139.0
CH2_k127_3159843_2 sequence-specific DNA binding - - - 0.000003833 55.0
CH2_k127_316049_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 487.0
CH2_k127_316049_1 EamA-like transporter family - - - 0.0000000000000000000000001996 111.0
CH2_k127_3171815_0 peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 375.0
CH2_k127_3176598_0 - - - - 0.000000001253 65.0
CH2_k127_3176598_2 - - - - 0.00000001819 63.0
CH2_k127_3176598_3 - - - - 0.00000261 58.0
CH2_k127_3179475_0 Protein of unknown function (DUF512) - - - 7.402e-245 763.0
CH2_k127_3179475_1 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 387.0
CH2_k127_3179475_2 TIGRFAM TonB family K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000001717 232.0
CH2_k127_3179475_3 biopolymer transport protein K03559,K03560 - - 0.0000000000000000000000000000000000000000000000000000000006269 207.0
CH2_k127_3179475_4 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000001191 177.0
CH2_k127_3179475_5 ExbD TolR family transport energizing protein K03559,K03560 - - 0.00000001038 62.0
CH2_k127_3200426_0 Major Facilitator Superfamily K02445 - - 5.481e-252 782.0
CH2_k127_3200426_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.264e-205 645.0
CH2_k127_3200426_2 phosphoglycolate phosphatase activity - - - 0.0000000000000000000000000000000001344 142.0
CH2_k127_3222799_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 5.453e-217 696.0
CH2_k127_3222799_1 Tfp pilus assembly protein tip-associated adhesin K02674 - - 1.412e-200 687.0
CH2_k127_3222799_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 308.0
CH2_k127_3249969_0 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01322 - 3.4.21.26 3.39e-262 814.0
CH2_k127_3249969_1 peptidase S9A, prolyl oligopeptidase domain protein beta-propeller K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 410.0
CH2_k127_3272591_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.102e-267 831.0
CH2_k127_3272591_1 ABC transporter K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 417.0
CH2_k127_3272591_2 - - - - 0.00000000000000000000007462 106.0
CH2_k127_3293816_0 Ribonuclease, Rne Rng family K08301 - - 2.164e-208 660.0
CH2_k127_3293816_1 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 467.0
CH2_k127_3293816_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000001299 245.0
CH2_k127_3293816_3 Aspartate decarboxylase K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000000001548 220.0
CH2_k127_3298034_0 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000004651 245.0
CH2_k127_3298034_1 Nitrite and sulphite reductase 4Fe-4S K00381,K00392 - 1.8.1.2,1.8.7.1 0.000000000000000000000000000000000000000000000000000000007461 203.0
CH2_k127_3298034_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000006728 96.0
CH2_k127_3298483_0 - - - - 8.362e-198 629.0
CH2_k127_3298483_1 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 416.0
CH2_k127_3298483_10 Scramblase - - - 0.0004649 49.0
CH2_k127_3298483_2 Pirin C-terminal cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 416.0
CH2_k127_3298483_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 412.0
CH2_k127_3298483_4 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000004254 199.0
CH2_k127_3298483_5 AMP binding - - - 0.000000000000000000000000000000000000000000002368 183.0
CH2_k127_3298483_6 TIGRFAM TonB family protein K03832 - - 0.00000000000000000000001106 110.0
CH2_k127_3298483_9 Domain of unknown function (DUF4349) - - - 0.0004062 51.0
CH2_k127_3303052_0 PFAM X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 1.299e-221 709.0
CH2_k127_3303052_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000005154 205.0
CH2_k127_3303052_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000007742 54.0
CH2_k127_336130_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1603.0
CH2_k127_336130_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1577.0
CH2_k127_3393408_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309,K11102 - - 4.651e-201 637.0
CH2_k127_3393408_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 415.0
CH2_k127_3393408_3 heme binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 308.0
CH2_k127_3393408_4 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 319.0
CH2_k127_3393408_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000007044 220.0
CH2_k127_3393408_6 protein conserved in bacteria K09793 - - 0.00000000000000000009757 96.0
CH2_k127_3415530_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 1.653e-213 672.0
CH2_k127_3415530_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 445.0
CH2_k127_3420493_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 5.173e-229 730.0
CH2_k127_3420493_1 glutamate synthase K12527 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0055114 1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 396.0
CH2_k127_342404_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 6.743e-298 926.0
CH2_k127_342404_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.902e-258 803.0
CH2_k127_342404_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 502.0
CH2_k127_342404_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 326.0
CH2_k127_342404_4 Belongs to the complex I subunit 6 family K00339 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000006431 143.0
CH2_k127_342404_5 GTP binding K06883 - - 0.0000000000000000000000003577 108.0
CH2_k127_3428880_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.143e-303 940.0
CH2_k127_3428880_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 302.0
CH2_k127_3428880_2 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000001689 211.0
CH2_k127_3428880_3 - K07164,K22391 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000004231 198.0
CH2_k127_3428880_4 - - - - 0.000000000000000000000000000000000000000000000003755 190.0
CH2_k127_3428880_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000002696 165.0
CH2_k127_3450282_0 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000004183 212.0
CH2_k127_3450282_1 peptidase activity, acting on L-amino acid peptides - - - 0.00000000000000000000000031 122.0
CH2_k127_3454811_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 1.158e-240 748.0
CH2_k127_3454811_2 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 577.0
CH2_k127_3454811_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 485.0
CH2_k127_3454811_4 PFAM Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001394 281.0
CH2_k127_3454811_5 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004964 271.0
CH2_k127_3454811_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006788 274.0
CH2_k127_347479_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 522.0
CH2_k127_347479_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 444.0
CH2_k127_347614_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004607 246.0
CH2_k127_347614_1 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000829 146.0
CH2_k127_3479655_0 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005305 247.0
CH2_k127_3479655_1 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000226 244.0
CH2_k127_3479655_2 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000000000000000000000000000544 211.0
CH2_k127_3479655_3 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000249 179.0
CH2_k127_3479655_4 SnoaL-like domain - - - 0.00000000000000000000000000000000000000546 150.0
CH2_k127_3479655_5 coenzyme F420 binding K07226 - - 0.000000000000000000000000000000006005 137.0
CH2_k127_3479655_6 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000521 129.0
CH2_k127_3479655_7 - - - - 0.0000000000000000000000000001074 119.0
CH2_k127_3479655_8 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000005131 113.0
CH2_k127_3510021_0 lysine biosynthetic process via aminoadipic acid - - - 3.837e-202 651.0
CH2_k127_3510021_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000008738 199.0
CH2_k127_3510021_2 Domain of unknown function (DUF4403) - - - 0.00000000000000000000000000000000000000000000000008129 183.0
CH2_k127_3534582_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 1.391e-294 929.0
CH2_k127_3534582_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 6.65e-196 627.0
CH2_k127_3534582_2 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 350.0
CH2_k127_3534582_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 334.0
CH2_k127_3534582_4 regulation of cell shape K04074,K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000001354 229.0
CH2_k127_3534582_5 2 iron, 2 sulfur cluster binding K07302,K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000386 223.0
CH2_k127_3534582_6 - - - - 0.0000000000000000000000000000000000000000000000000000000001831 213.0
CH2_k127_3534582_7 XdhC and CoxI family - - - 0.00000000000000000000000000000000000000000000000000001748 196.0
CH2_k127_3534582_8 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000001528 187.0
CH2_k127_3534582_9 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000001645 98.0
CH2_k127_3598190_0 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 531.0
CH2_k127_3598190_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000001652 200.0
CH2_k127_3620806_0 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 445.0
CH2_k127_3620806_1 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 331.0
CH2_k127_3620806_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004402 246.0
CH2_k127_3634996_0 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 530.0
CH2_k127_3634996_1 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 370.0
CH2_k127_3634996_2 Alpha-1,2-mannosidase - - - 0.000000000000000000000000000000000000001972 154.0
CH2_k127_3634996_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000001678 96.0
CH2_k127_3693749_0 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 402.0
CH2_k127_3693749_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 378.0
CH2_k127_3693749_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000004072 206.0
CH2_k127_3693749_3 PHP domain protein - - - 0.0000000000000000000000000000000002915 153.0
CH2_k127_3693749_4 amine dehydrogenase activity K07004 - - 0.000000000000000000000000139 124.0
CH2_k127_3693749_5 Parallel beta-helix repeats - - - 0.00000000000001563 88.0
CH2_k127_3725607_0 Pyridine nucleotide-disulphide oxidoreductase K00266,K00528,K17722 - 1.18.1.2,1.19.1.1,1.3.1.1,1.4.1.13,1.4.1.14 5.908e-222 705.0
CH2_k127_3725607_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 297.0
CH2_k127_3725607_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002503 261.0
CH2_k127_3725607_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000000000001932 212.0
CH2_k127_3725607_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000000003275 164.0
CH2_k127_379836_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 2.632e-284 883.0
CH2_k127_379836_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02482 - 2.7.13.3 7.074e-225 706.0
CH2_k127_379836_2 Aldehyde dehydrogenase family K00128 - 1.2.1.3 3.422e-197 629.0
CH2_k127_379836_3 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 595.0
CH2_k127_379836_4 phosphorelay signal transduction system K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 495.0
CH2_k127_379836_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 417.0
CH2_k127_379836_6 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002911 255.0
CH2_k127_3802830_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 585.0
CH2_k127_3802830_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 367.0
CH2_k127_3802830_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000002322 213.0
CH2_k127_3802830_3 RmlD substrate binding domain K15856 - 1.1.1.281 0.000000000000000000000000000000001634 141.0
CH2_k127_3802830_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000002402 134.0
CH2_k127_3802830_5 Methyltransferase domain - - - 0.00000000000000000002333 102.0
CH2_k127_3802830_6 sugar transferase - - - 0.00000000001716 77.0
CH2_k127_3810972_0 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.0000004049 60.0
CH2_k127_3863689_0 PFAM peptidase M61 - - - 1.894e-219 698.0
CH2_k127_3863689_1 Serine dehydratase beta chain K01752 - 4.3.1.17 5.041e-196 621.0
CH2_k127_3863689_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 319.0
CH2_k127_3863689_3 Domain of unknown function (DUF2520) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 281.0
CH2_k127_3863689_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005306 270.0
CH2_k127_3863689_5 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE) K06169 - - 0.000000000000000000000000000000000000000000000000000000000007625 217.0
CH2_k127_3863689_6 aminotransferase K14287 - 2.6.1.88 0.00000000000000000000002129 113.0
CH2_k127_3895801_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 545.0
CH2_k127_3895801_2 Domain of unknown function (DUF4410) - - - 0.0002615 48.0
CH2_k127_3903915_0 peptidase dimerisation domain - - - 1.391e-263 819.0
CH2_k127_3903915_1 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009947 411.0
CH2_k127_3903915_3 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 359.0
CH2_k127_3903915_4 peptidase K21471 GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000003071 226.0
CH2_k127_3903915_6 - - - - 0.00000000000000222 77.0
CH2_k127_3930416_0 PFAM ABC transporter K11085 - - 1.634e-266 831.0
CH2_k127_3930416_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 548.0
CH2_k127_3930416_3 Class-II DAHP synthetase family K01626 - 2.5.1.54 0.00000004684 57.0
CH2_k127_3930416_4 cellulase activity - - - 0.00005348 53.0
CH2_k127_3948588_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 463.0
CH2_k127_3948588_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 350.0
CH2_k127_3956688_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1454.0
CH2_k127_3956688_1 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 569.0
CH2_k127_3956688_2 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008547 509.0
CH2_k127_3956688_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 446.0
CH2_k127_3956688_4 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 364.0
CH2_k127_3956688_5 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 368.0
CH2_k127_3956688_6 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 362.0
CH2_k127_3956688_7 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000000000008881 90.0
CH2_k127_3956688_8 - - - - 0.00000000000001473 82.0
CH2_k127_3969724_0 COG0515 Serine threonine protein - - - 0.00000000000000001829 97.0
CH2_k127_3969724_1 ERAD pathway - - - 0.000000000000611 76.0
CH2_k127_397451_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 482.0
CH2_k127_397451_1 deaminase activity K01488,K19572,K21053 - 3.5.4.2,3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 323.0
CH2_k127_397451_2 - - - - 0.00003241 48.0
CH2_k127_3988678_0 queuine tRNA-ribosyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008503 250.0
CH2_k127_3988678_1 - - - - 0.00000000000000000000000000000000000000000000000000001036 201.0
CH2_k127_3988678_2 Helix-turn-helix - - - 0.00000000000000000000000000000000007011 140.0
CH2_k127_3988678_3 Protein of unknown function (DUF2493) - - - 0.0000000000000000000000000001249 119.0
CH2_k127_3988678_4 Subunit R is required for both nuclease and ATPase activities, but not for modification - - - 0.000000000000000002628 90.0
CH2_k127_3988678_5 KTSC domain - - - 0.000000000000001577 83.0
CH2_k127_3988678_8 - - - - 0.000001017 58.0
CH2_k127_4000680_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 454.0
CH2_k127_4000680_1 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009821 414.0
CH2_k127_4000680_3 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000003371 161.0
CH2_k127_4029330_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.036e-304 943.0
CH2_k127_4029330_1 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 353.0
CH2_k127_4029330_2 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 350.0
CH2_k127_4029330_4 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000007171 129.0
CH2_k127_4031374_0 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 608.0
CH2_k127_4031374_1 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003466 275.0
CH2_k127_4037094_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 550.0
CH2_k127_4037094_1 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 519.0
CH2_k127_4037094_2 Coenzyme A transferase K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 405.0
CH2_k127_4037094_3 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 400.0
CH2_k127_4037094_4 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 284.0
CH2_k127_4037094_5 positive regulation of transcription, DNA-templated K06206 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044238,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008451 278.0
CH2_k127_4037094_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000002662 182.0
CH2_k127_4098740_0 coproporphyrinogen oxidase activity K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 1.419e-207 655.0
CH2_k127_4098740_1 Ferrochelatase K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 408.0
CH2_k127_4098740_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 347.0
CH2_k127_4098740_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000001508 117.0
CH2_k127_4098740_4 - - - - 0.00001008 56.0
CH2_k127_410063_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 597.0
CH2_k127_410063_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000004882 119.0
CH2_k127_4150941_0 Peptidase family M1 domain - - - 2.412e-298 929.0
CH2_k127_4150941_2 - - - - 0.00003242 57.0
CH2_k127_4198204_0 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 537.0
CH2_k127_4198204_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 380.0
CH2_k127_4198204_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 288.0
CH2_k127_4198204_3 Protein of unknown function (DUF1579) - - - 0.00001059 56.0
CH2_k127_4198860_0 PFAM Organic solvent tolerance protein K04744 - - 3.592e-277 874.0
CH2_k127_4198860_1 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 437.0
CH2_k127_4198860_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 335.0
CH2_k127_4198860_3 ZIP Zinc transporter K07238,K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 325.0
CH2_k127_4198926_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000001931 198.0
CH2_k127_4198926_1 response regulator, receiver K09763 - - 0.0000000000000000000000000000000000000000000000000000009849 203.0
CH2_k127_4198926_2 protein conserved in bacteria K09857 - - 0.0000001432 56.0
CH2_k127_4208965_0 regulation of single-species biofilm formation K13573 - - 4.108e-299 928.0
CH2_k127_4208965_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005505 270.0
CH2_k127_4222995_0 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 347.0
CH2_k127_4222995_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008975 245.0
CH2_k127_4222995_2 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000001568 209.0
CH2_k127_4222995_3 PLD-like domain K06131 - - 0.000000000000000000000000000000000000000000000007555 180.0
CH2_k127_4249782_0 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 516.0
CH2_k127_4249782_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 414.0
CH2_k127_4249782_2 PFAM Alpha beta hydrolase K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 377.0
CH2_k127_4249782_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 310.0
CH2_k127_4249782_4 PFAM Chemotaxis methyl-accepting receptor, signalling - - - 0.00000000000000000000000007154 113.0
CH2_k127_4249782_5 Protein tyrosine kinase - - - 0.000000000000000006621 89.0
CH2_k127_4290446_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 366.0
CH2_k127_4290446_1 Ribosomal prokaryotic L21 protein K02888 - - 0.0000000000000000000000000000000000000000592 164.0
CH2_k127_4290446_2 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000001503 131.0
CH2_k127_4321739_0 Carboxypeptidase regulatory-like domain - - - 2.327e-264 830.0
CH2_k127_4378043_0 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 451.0
CH2_k127_4378043_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 432.0
CH2_k127_4378043_2 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 431.0
CH2_k127_4378043_3 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 367.0
CH2_k127_4378043_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 310.0
CH2_k127_4378043_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.000000000000000000000000000000000000000000000000000000000000000000008774 239.0
CH2_k127_4378043_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000003017 175.0
CH2_k127_4380518_0 DNA-binding helix-turn-helix protein - - - 0.0001185 53.0
CH2_k127_4382354_0 RecQ zinc-binding K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 455.0
CH2_k127_4382354_1 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001735 271.0
CH2_k127_4382354_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 265.0
CH2_k127_4382354_3 - - - - 0.0000000000000000000000000000000000001281 147.0
CH2_k127_4382354_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000004937 150.0
CH2_k127_4382354_5 Carboxymuconolactone decarboxylase family - - - 0.000000007668 58.0
CH2_k127_4382696_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 2.612e-259 814.0
CH2_k127_4388722_0 Cys Met metabolism K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 580.0
CH2_k127_4388722_1 CYTH K05873 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000001352 223.0
CH2_k127_4388722_3 - - - - 0.0000000000000000000000002772 111.0
CH2_k127_4401856_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 581.0
CH2_k127_4401856_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 291.0
CH2_k127_4401856_2 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000453 282.0
CH2_k127_4401856_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000007498 191.0
CH2_k127_4408224_0 membrane K07148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 349.0
CH2_k127_4408224_1 Cupin domain - - - 0.00000000000000000000000000000000000000000003779 177.0
CH2_k127_4415597_0 PFAM ABC transporter - - - 3.458e-252 781.0
CH2_k127_4415597_1 conserved secreted or membrane protein precursor - - - 0.00000000000000133 85.0
CH2_k127_4462522_0 Belongs to the MurCDEF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 559.0
CH2_k127_4462522_1 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 429.0
CH2_k127_4462522_2 FOG TPR repeat - - - 0.0000000001107 68.0
CH2_k127_4462522_3 - - - - 0.0000008127 56.0
CH2_k127_4462522_4 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0002845 44.0
CH2_k127_4475493_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 6.513e-223 699.0
CH2_k127_4475493_2 Zinc carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000004394 206.0
CH2_k127_4475493_3 lipid kinase activity K07029 - 2.7.1.107 0.000000000000000000000000000000000001895 139.0
CH2_k127_4476006_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 558.0
CH2_k127_4476006_1 Two component transcriptional regulator, winged helix family K02483,K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 307.0
CH2_k127_4476006_2 - K01387,K06399 - 3.4.21.116,3.4.24.3 0.000000000000000000000000000000000000000000000000000000000000000000006621 252.0
CH2_k127_4476006_3 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000469 184.0
CH2_k127_4476006_4 PhoQ Sensor - - - 0.000000000000000000113 91.0
CH2_k127_4476006_5 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.000000000001199 79.0
CH2_k127_4478755_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 477.0
CH2_k127_4478755_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 369.0
CH2_k127_4478755_2 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000006321 137.0
CH2_k127_4485364_0 RNA polymerase sigma-54 factor K03092 - - 2.658e-230 722.0
CH2_k127_4485364_2 PFAM ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 399.0
CH2_k127_4485364_3 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000002839 91.0
CH2_k127_4507012_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 598.0
CH2_k127_4507012_2 Histidine kinase-like ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001095 291.0
CH2_k127_4507012_3 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000001706 223.0
CH2_k127_4522076_0 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 397.0
CH2_k127_4522076_1 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000003598 136.0
CH2_k127_4551437_0 ABC transporter transmembrane K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 571.0
CH2_k127_4551437_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000004846 151.0
CH2_k127_4559665_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 465.0
CH2_k127_4559665_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001715 274.0
CH2_k127_4559665_2 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004636 250.0
CH2_k127_4559665_3 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000009345 181.0
CH2_k127_4559665_5 Ribosomal L32p protein family K02911 - - 0.000000000000000000000000000156 115.0
CH2_k127_4583419_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 7.4e-323 998.0
CH2_k127_4583419_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000624 189.0
CH2_k127_4583419_2 Protein of unknown function (DUF1648) - - - 0.00000000000004814 81.0
CH2_k127_4598640_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 421.0
CH2_k127_4598640_1 Inner membrane protein CreD K06143 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 388.0
CH2_k127_4600435_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 590.0
CH2_k127_4600435_1 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000339 125.0
CH2_k127_4610847_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 507.0
CH2_k127_4610847_1 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 485.0
CH2_k127_4610847_2 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 475.0
CH2_k127_4610847_3 methenyltetrahydrofolate cyclohydrolase activity K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 470.0
CH2_k127_4610847_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 334.0
CH2_k127_4610847_6 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000000000000000007313 229.0
CH2_k127_4610847_7 Acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000008192 222.0
CH2_k127_4610847_8 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000003921 165.0
CH2_k127_4650103_0 phosphorelay signal transduction system K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 354.0
CH2_k127_4650103_1 phosphorelay sensor kinase activity K02478,K07315,K07704 - 2.7.13.3,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 317.0
CH2_k127_4650103_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000407 184.0
CH2_k127_4650103_4 PFAM PKD domain containing protein - - - 0.00002493 50.0
CH2_k127_4676309_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.82e-212 663.0
CH2_k127_4676309_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 353.0
CH2_k127_4676309_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000000000000000000000000000000000000308 228.0
CH2_k127_4676309_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000001166 171.0
CH2_k127_4676309_4 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.000000000000000000000000000000000000000004162 159.0
CH2_k127_4676309_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000002862 141.0
CH2_k127_4676309_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000002106 78.0
CH2_k127_468057_0 - - - - 0.000000000000000000000000000000000000000000000000000000005626 202.0
CH2_k127_468057_1 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000579 203.0
CH2_k127_468057_2 Uncharacterized protein conserved in bacteria (DUF2200) - - - 0.000000000000000000000000000000000000000000000000000646 200.0
CH2_k127_468057_3 NmrA-like family - - - 0.00000000000000000000000000000000000000001056 169.0
CH2_k127_468057_4 - - - - 0.00000000000000000000783 94.0
CH2_k127_468057_5 shikimate kinase activity K00891 - 2.7.1.71 0.0000000000000000000514 96.0
CH2_k127_468057_6 - - - - 0.0000000000007249 77.0
CH2_k127_468110_0 Carboxyl transferase domain - - - 4.877e-281 870.0
CH2_k127_468851_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.396e-231 724.0
CH2_k127_468851_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region - - - 3.05e-225 707.0
CH2_k127_468851_3 RHS protein - - - 0.0001791 51.0
CH2_k127_4690427_1 Heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 406.0
CH2_k127_4690427_2 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 336.0
CH2_k127_4690427_4 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000006982 112.0
CH2_k127_4690427_5 Ferredoxin K01768,K04755 - 4.6.1.1 0.0000000000000000000000002274 109.0
CH2_k127_4706490_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 7.566e-194 610.0
CH2_k127_4706490_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 508.0
CH2_k127_4706490_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 317.0
CH2_k127_4706490_3 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 297.0
CH2_k127_4706490_4 protein transport K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000004244 119.0
CH2_k127_4706490_5 TIGRFAM TonB family K03832 - - 0.0000000000000001864 82.0
CH2_k127_4727407_0 polysaccharide catabolic process - - - 2.263e-212 687.0
CH2_k127_4727407_1 Amino acid permease K03294 - - 1.765e-202 640.0
CH2_k127_4727407_2 Membrane - - - 1.697e-200 634.0
CH2_k127_4727407_3 PFAM Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 512.0
CH2_k127_4727407_4 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 462.0
CH2_k127_4727407_5 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 399.0
CH2_k127_4727407_6 phosphorelay signal transduction system K07720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001913 250.0
CH2_k127_4727407_7 competence protein - GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0000000003603 72.0
CH2_k127_4736621_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.256e-317 981.0
CH2_k127_4736621_13 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000001728 54.0
CH2_k127_4736621_2 Type II/IV secretion system protein K02669 - - 5.937e-217 678.0
CH2_k127_4736621_3 Type II secretion system (T2SS), protein F K02455 - - 1.791e-194 613.0
CH2_k127_4736621_4 cyclic-guanylate-specific phosphodiesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 394.0
CH2_k127_4736621_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 384.0
CH2_k127_4736621_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 362.0
CH2_k127_4736621_7 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 336.0
CH2_k127_4736621_8 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000001817 240.0
CH2_k127_4736621_9 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02031,K02032,K02033,K02034,K12370,K13891,K15582,K15583,K15586,K15587,K16201 GO:0000041,GO:0003674,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015099,GO:0015318,GO:0015675,GO:0016020,GO:0016021,GO:0016151,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0035444,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098655,GO:0098660,GO:0098662 3.6.3.24 0.0000000000000000000000000000000000000000000000000000000000886 213.0
CH2_k127_4740319_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 5.048e-251 803.0
CH2_k127_4740319_1 DEAD DEAH box helicase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 342.0
CH2_k127_4740319_2 DEAD DEAH box helicase domain protein - - - 0.00000000000000000000000000000000000003635 145.0
CH2_k127_4757393_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.257e-268 830.0
CH2_k127_4757393_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 567.0
CH2_k127_4757393_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006118 271.0
CH2_k127_4757393_3 Protein of unknown function (DUF1569) - - - 0.00000000000000000000000000000000002257 141.0
CH2_k127_4757393_4 Putative zincin peptidase - - - 0.0000000000000000000000000004534 123.0
CH2_k127_4757393_5 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.000000000000000000000000002631 111.0
CH2_k127_476321_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 369.0
CH2_k127_476321_1 PFAM Abortive infection protein K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007577 278.0
CH2_k127_476321_2 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003378 267.0
CH2_k127_476321_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000001235 170.0
CH2_k127_476321_4 KR domain - - - 0.000000000000000000000000000000001969 146.0
CH2_k127_4769220_0 TamB, inner membrane protein subunit of TAM complex K07277,K09800 - - 1.869e-305 969.0
CH2_k127_4769220_1 protein kinase activity - - - 0.000000000000000000000000000000000000000001076 165.0
CH2_k127_4836604_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1015.0
CH2_k127_4836604_1 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 365.0
CH2_k127_4836604_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 343.0
CH2_k127_4836604_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000003488 245.0
CH2_k127_4836604_4 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.0000000000000000000000000000000000000000002237 163.0
CH2_k127_4849775_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1358.0
CH2_k127_4849775_1 Surface antigen variable number K07277 - - 0.0 1195.0
CH2_k127_4849775_11 cAMP biosynthetic process - - - 0.00000003237 57.0
CH2_k127_4849775_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 531.0
CH2_k127_4849775_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 473.0
CH2_k127_4849775_5 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 407.0
CH2_k127_4849775_6 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 383.0
CH2_k127_4849775_7 PFAM response regulator receiver K07665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 313.0
CH2_k127_4849775_8 dUTPase K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000001158 233.0
CH2_k127_4849775_9 Ceramidase - - - 0.000000000000000000000000000000000000000000000000000000000000002952 226.0
CH2_k127_4876027_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 521.0
CH2_k127_4876027_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 425.0
CH2_k127_4876027_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000000005422 213.0
CH2_k127_4876027_4 Exopolysaccharide synthesis, ExoD - - - 0.0000000000002135 74.0
CH2_k127_4889821_0 phosphorelay signal transduction system K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 344.0
CH2_k127_4889821_1 Histidine kinase K02478,K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 312.0
CH2_k127_4889821_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006924 274.0
CH2_k127_4889821_3 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000001597 216.0
CH2_k127_489993_0 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 452.0
CH2_k127_489993_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 365.0
CH2_k127_489993_2 LytTr DNA-binding domain K02477 - - 0.000000000000003397 75.0
CH2_k127_4973457_0 Dehydrogenase E1 component K11381 - 1.2.4.4 0.0 1131.0
CH2_k127_4973457_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000512 250.0
CH2_k127_4973457_2 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000002137 94.0
CH2_k127_4973457_3 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000008304 92.0
CH2_k127_4989070_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 323.0
CH2_k127_4993942_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 574.0
CH2_k127_4993942_1 sporulation resulting in formation of a cellular spore K06412 - - 0.000000000000003412 77.0
CH2_k127_500669_0 membrane organization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 536.0
CH2_k127_500669_1 Ankyrin repeat - - - 0.000000000000000000000000000009319 129.0
CH2_k127_500669_2 Type II/IV secretion system protein K02669 - - 0.00000007446 61.0
CH2_k127_50164_0 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 563.0
CH2_k127_50164_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 296.0
CH2_k127_50164_2 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000004345 141.0
CH2_k127_5048165_1 Thioesterase K01075 - 3.1.2.23 0.000000000000000000000000000000000000000000001335 168.0
CH2_k127_5048165_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000004811 141.0
CH2_k127_5054988_0 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000477 123.0
CH2_k127_5054988_1 STAS domain - - - 0.00000000001037 68.0
CH2_k127_5054988_2 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000004396 68.0
CH2_k127_5054988_3 Domain of unknown function (DUF4349) - - - 0.00009515 50.0
CH2_k127_5065867_0 Acyclic terpene utilisation family protein AtuA - - - 1.866e-252 783.0
CH2_k127_5065867_1 - - - - 0.0000000000000000000000000000000000000000000000000001956 194.0
CH2_k127_5139332_0 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 537.0
CH2_k127_5146748_0 Belongs to the helicase family. UvrD subfamily - - - 1.156e-258 818.0
CH2_k127_5155731_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 5.437e-247 773.0
CH2_k127_5155731_1 PFAM NADH Ubiquinone plastoquinone (complex I) K05568,K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 514.0
CH2_k127_5162928_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003039 269.0
CH2_k127_5162928_1 - - - - 0.00000000000000000000000000000000000000000000005639 180.0
CH2_k127_5162928_2 Cold shock protein domain K03704 - - 0.00000000000000000000000000000004727 138.0
CH2_k127_5162928_3 LNS2 - - - 0.0000000000000000000000002778 117.0
CH2_k127_5162928_5 - - - - 0.0000000000000008836 79.0
CH2_k127_5188934_0 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 5.853e-237 744.0
CH2_k127_5188934_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000001624 189.0
CH2_k127_5188934_2 DNA-binding transcription factor activity - - - 0.0000000000000000000003924 98.0
CH2_k127_5188934_3 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000215 79.0
CH2_k127_5226897_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.935e-241 752.0
CH2_k127_5245017_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 590.0
CH2_k127_5245017_2 DNA-directed DNA polymerase activity K02342,K03763 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 285.0
CH2_k127_5245017_3 bacterial-type flagellum organization K02282,K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000466 231.0
CH2_k127_5245017_4 - - - - 0.000000000000000000000000000000000000000000000000000002582 194.0
CH2_k127_5253771_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 541.0
CH2_k127_5253771_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 426.0
CH2_k127_5253771_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000005342 195.0
CH2_k127_5253771_3 PFAM helix-turn-helix, Fis-type - - - 0.000000000000000000000005537 103.0
CH2_k127_5293106_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 1.802e-233 767.0
CH2_k127_5293106_1 Protein of unknown function, DUF480 K09915 - - 0.00000000000000000000000000000000000000000000000000002253 195.0
CH2_k127_534909_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 2.025e-224 704.0
CH2_k127_534909_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 479.0
CH2_k127_534909_2 Prolyl oligopeptidase family - - - 0.00000000000000000000003748 101.0
CH2_k127_5350247_0 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 437.0
CH2_k127_5350247_1 virulence factor MVIN family protein K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000002656 228.0
CH2_k127_5350247_2 sequence-specific DNA binding K03719 - - 0.000000000000000000000000000000000000000000000002047 178.0
CH2_k127_5350247_3 DinB superfamily - - - 0.00009384 47.0
CH2_k127_5360513_0 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 505.0
CH2_k127_5360513_1 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 370.0
CH2_k127_5360513_2 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000001701 201.0
CH2_k127_5360513_3 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000009551 154.0
CH2_k127_5439770_0 PFAM Uncharacterised conserved protein UCP033563 - - - 1.05e-219 688.0
CH2_k127_5439770_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 5.632e-203 635.0
CH2_k127_5439770_10 PFAM SpoVT AbrB K07172,K18842 - - 0.000000007267 59.0
CH2_k127_5439770_2 Thiolase, C-terminal domain K00626 GO:0003674,GO:0003824,GO:0003985,GO:0003988,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016043,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0019395,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0032787,GO:0034440,GO:0042737,GO:0042802,GO:0043436,GO:0043438,GO:0043442,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046459,GO:0046950,GO:0046952,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901568,GO:1901569,GO:1901575,GO:1902224 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 576.0
CH2_k127_5439770_3 Cell division ATP-binding protein ftsE K09811,K09812 GO:0000166,GO:0000287,GO:0000910,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0007049,GO:0008144,GO:0008150,GO:0008356,GO:0009898,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019897,GO:0019898,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0030145,GO:0030554,GO:0031234,GO:0032153,GO:0032506,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042173,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043937,GO:0043938,GO:0044085,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0046677,GO:0046872,GO:0046914,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 375.0
CH2_k127_5439770_4 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 337.0
CH2_k127_5439770_5 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 343.0
CH2_k127_5439770_6 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 333.0
CH2_k127_5439770_7 Predicted membrane protein (DUF2238) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 295.0
CH2_k127_5439770_8 Fic/DOC family K07341 - - 0.000000000000000000000000009869 113.0
CH2_k127_5439770_9 - - - - 0.000000000000000000001382 108.0
CH2_k127_544009_0 Transcriptional regulator K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 379.0
CH2_k127_544009_1 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 298.0
CH2_k127_5450692_0 peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000006896 212.0
CH2_k127_5450692_2 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458 - 2.3.1.179 0.000000000007069 66.0
CH2_k127_5506202_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 477.0
CH2_k127_5506202_1 PFAM Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 436.0
CH2_k127_5506202_2 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 402.0
CH2_k127_5506202_3 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000001505 167.0
CH2_k127_5506202_4 peptidase, M28 - - - 0.00000000000000000000000000000007571 131.0
CH2_k127_5527400_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 412.0
CH2_k127_5527400_1 lipopolysaccharide transmembrane transporter activity K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 376.0
CH2_k127_5527400_2 phosphorelay signal transduction system K15012 - - 0.00000000000000000000000000000000000000001983 155.0
CH2_k127_5531035_0 C-terminus of AA_permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 469.0
CH2_k127_5531035_1 esterase of the alpha beta K07002 - - 0.00000000002042 64.0
CH2_k127_5531035_2 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000001112 60.0
CH2_k127_5535420_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007259 299.0
CH2_k127_5535420_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000122 259.0
CH2_k127_5535420_2 FAD linked oxidases, C-terminal domain - - - 0.000000000000004266 77.0
CH2_k127_5561452_0 PhoD-like phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 344.0
CH2_k127_5561452_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000005833 260.0
CH2_k127_5561452_2 glyoxalase III activity - - - 0.0000000000000000000000000000001274 130.0
CH2_k127_5561452_4 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.000000000006282 67.0
CH2_k127_5569300_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 531.0
CH2_k127_5569300_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 359.0
CH2_k127_5569300_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000005239 86.0
CH2_k127_5569300_3 Protein kinase domain K12132 - 2.7.11.1 0.0000000342 56.0
CH2_k127_5577514_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 1.197e-208 658.0
CH2_k127_5577514_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 294.0
CH2_k127_5577514_3 membrane K07148 - - 0.0000000000000000000000000000000000000000000000000000000000000001733 237.0
CH2_k127_5600806_0 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000001788 170.0
CH2_k127_5600806_1 receptor K02014,K16092 - - 0.000000006527 69.0
CH2_k127_5621474_0 Peptidase family M49 K01277 - 3.4.14.4 1.981e-250 794.0
CH2_k127_5621474_1 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 424.0
CH2_k127_5621474_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 311.0
CH2_k127_5621474_3 PFAM Glycosyl transferase family 2 - - - 0.000000002294 58.0
CH2_k127_564109_0 GTPase activity K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 536.0
CH2_k127_564109_1 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 427.0
CH2_k127_564109_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 422.0
CH2_k127_564109_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 360.0
CH2_k127_564109_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 331.0
CH2_k127_5693102_0 Bacterial conjugation TrbI-like protein K03195,K20533 - - 0.000000000002258 77.0
CH2_k127_5740152_0 ATP-independent chaperone mediated protein folding K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 518.0
CH2_k127_5740152_1 Phosphatidylethanolamine-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 335.0
CH2_k127_5740152_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 295.0
CH2_k127_5740152_3 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 309.0
CH2_k127_5740152_4 PFAM PKD domain containing protein - - - 0.000000000000000000000000000002432 138.0
CH2_k127_5740152_5 metallopeptidase activity - - - 0.0000000000193 78.0
CH2_k127_5744937_0 Beta-eliminating lyase K01668 - 4.1.99.2 2.321e-211 666.0
CH2_k127_5744937_1 PFAM NAD dependent epimerase dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 367.0
CH2_k127_5767671_0 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 305.0
CH2_k127_5767671_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K03437 - 2.1.1.185 0.00000004088 55.0
CH2_k127_5778460_0 Dehydrogenase E1 component K11381 - 1.2.4.4 0.0 1201.0
CH2_k127_5778460_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.107e-245 769.0
CH2_k127_5778460_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 514.0
CH2_k127_5778460_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 437.0
CH2_k127_5778460_4 COGs COG0110 Acetyltransferase (isoleucine patch superfamily) K00633 - 2.3.1.18 0.0000000000000000000000000000000000000000000000000000000000000000002409 238.0
CH2_k127_5778460_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000001695 137.0
CH2_k127_5778460_6 PhoQ Sensor - - - 0.00000000000000000000000000002192 123.0
CH2_k127_5778460_8 transcriptional regulator - - - 0.0000000002982 69.0
CH2_k127_5831284_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 4.277e-221 697.0
CH2_k127_5831284_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 437.0
CH2_k127_5831284_2 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 404.0
CH2_k127_5831284_3 sigma factor antagonist activity K04757,K07315 - 2.7.11.1,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000001253 221.0
CH2_k127_5831284_4 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000004012 161.0
CH2_k127_5831284_5 antisigma factor binding K04749,K06378 - - 0.000000000000000000000000000000000008642 146.0
CH2_k127_5831284_6 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.000000000000000000000000000001717 121.0
CH2_k127_5831284_7 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000001872 123.0
CH2_k127_5831284_9 Belongs to the peptidase M48B family K03799 - - 0.000000005486 64.0
CH2_k127_5857794_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 5.023e-209 654.0
CH2_k127_5857794_1 Type II/IV secretion system protein - - - 2.805e-205 655.0
CH2_k127_5857794_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 524.0
CH2_k127_5857794_3 Bacterial capsule synthesis protein PGA_cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 475.0
CH2_k127_5857794_4 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 423.0
CH2_k127_5857794_5 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 405.0
CH2_k127_5857794_6 gluconolactonase activity K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000171 191.0
CH2_k127_5857794_7 acyl-coa hydrolase K01073 - 3.1.2.20 0.00000000000000000000000000000000000000000000000007832 181.0
CH2_k127_5857794_8 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000000000000001009 151.0
CH2_k127_5857794_9 XdhC and CoxI family - - - 0.0000000000000000000000000000008343 124.0
CH2_k127_5898865_0 Ras family - - - 1.525e-251 790.0
CH2_k127_5898865_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002586 274.0
CH2_k127_5921379_0 Cys Met metabolism - - - 8.414e-196 617.0
CH2_k127_5921379_2 thiamine diphosphate biosynthetic process K03149,K03154 GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.0000000000000000000000001653 106.0
CH2_k127_5949161_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 543.0
CH2_k127_5949161_1 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 342.0
CH2_k127_5949161_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001661 259.0
CH2_k127_5964479_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 403.0
CH2_k127_5964479_1 Endonuclease containing a URI domain K07461 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000000000000000009019 117.0
CH2_k127_5970386_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 6.735e-201 631.0
CH2_k127_5970386_1 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009779 392.0
CH2_k127_5981111_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 418.0
CH2_k127_5981111_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000003934 57.0
CH2_k127_5998581_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 571.0
CH2_k127_5998581_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 497.0
CH2_k127_5998581_2 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 449.0
CH2_k127_5998581_3 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 437.0
CH2_k127_5998581_4 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 431.0
CH2_k127_5998581_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000215 208.0
CH2_k127_6005608_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 376.0
CH2_k127_6005608_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000008265 167.0
CH2_k127_6005608_2 PFAM binding-protein-dependent transport systems inner membrane component K02033,K15581 - - 0.00000000000000000000000000000000000000003561 165.0
CH2_k127_6005608_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000003722 135.0
CH2_k127_6005608_4 nUDIX hydrolase K03574 - 3.6.1.55 0.00000000000000000000000000003938 124.0
CH2_k127_612242_0 ABC transporter - - - 1.486e-204 658.0
CH2_k127_612242_1 ABC transporter - - - 0.000000007381 68.0
CH2_k127_6147040_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000003297 248.0
CH2_k127_6147040_1 Protein of unknown function (DUF418) K07148 - - 0.00000000000000000000000000000000000000000000000000001359 201.0
CH2_k127_6159211_0 Belongs to the heme-copper respiratory oxidase family K00404,K15862 - 1.9.3.1 1.5e-323 1003.0
CH2_k127_6159211_1 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.0000000000000000000000000000000003135 138.0
CH2_k127_6159211_2 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000002401 90.0
CH2_k127_6159211_3 cytochrome oxidase maturation protein cbb3-type - - - 0.000001349 57.0
CH2_k127_6182558_0 response regulator, receiver K20977 - - 0.0000000000000000000000000000000000000000000000000000000000000000005312 238.0
CH2_k127_6182558_1 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000000000000000000000000000000000000009174 191.0
CH2_k127_6182558_2 Surface antigen variable number - - - 0.00000000000000000004251 95.0
CH2_k127_6187850_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 387.0
CH2_k127_6187850_1 Glycoside hydrolase family 44 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001037 278.0
CH2_k127_6187850_3 domain, Protein K01179 - 3.2.1.4 0.000000000000000000000004899 121.0
CH2_k127_6187850_4 phosphorelay signal transduction system K02477 - - 0.000000000000004737 76.0
CH2_k127_6232644_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000008252 233.0
CH2_k127_6232644_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000002396 211.0
CH2_k127_6261226_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 0.0 1094.0
CH2_k127_6261226_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 591.0
CH2_k127_6261226_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000005782 72.0
CH2_k127_6261226_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 476.0
CH2_k127_6261226_3 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 457.0
CH2_k127_6261226_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 393.0
CH2_k127_6261226_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 346.0
CH2_k127_6261226_6 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 329.0
CH2_k127_6261226_7 Conserved Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008136 265.0
CH2_k127_6261226_8 DinB family - - - 0.00000000000000000000000000003122 123.0
CH2_k127_6261226_9 DinB family - - - 0.00000000000000000001663 98.0
CH2_k127_6282061_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 584.0
CH2_k127_6362970_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 600.0
CH2_k127_6362970_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 580.0
CH2_k127_6362970_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 349.0
CH2_k127_6362970_3 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001862 261.0
CH2_k127_6362970_4 SMART serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005522 245.0
CH2_k127_6362970_5 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000005721 209.0
CH2_k127_6362970_6 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000002606 149.0
CH2_k127_6405157_0 TrkA-C domain K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 476.0
CH2_k127_6405157_1 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 451.0
CH2_k127_6405157_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 381.0
CH2_k127_6405157_3 thiolester hydrolase activity K17362 - - 0.000000000000000000000000000000000000000000000000000000000002771 212.0
CH2_k127_6405157_4 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0001663 48.0
CH2_k127_6429281_0 Zinc carboxypeptidase - - - 3.775e-271 850.0
CH2_k127_6429281_1 Tetratricopeptide repeat K12132 - 2.7.11.1 0.00000748 52.0
CH2_k127_6478853_0 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 411.0
CH2_k127_6478853_3 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000005182 73.0
CH2_k127_6495073_0 PFAM ABC transporter - - - 4.411e-312 968.0
CH2_k127_6495073_1 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 602.0
CH2_k127_6495073_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 382.0
CH2_k127_6495073_3 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 305.0
CH2_k127_6495073_4 isomerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 305.0
CH2_k127_6495073_5 biotin-[acetyl-CoA-carboxylase] ligase activity K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004379 278.0
CH2_k127_6495073_6 Histidine kinase - - - 0.00000000000000000000003065 100.0
CH2_k127_6495073_7 - - - - 0.0000000325 59.0
CH2_k127_6498650_0 Binding-protein-dependent transport system inner membrane component K10003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 336.0
CH2_k127_6498650_1 Binding-protein-dependent transport system inner membrane component K10002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 283.0
CH2_k127_6593596_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1156.0
CH2_k127_6593596_1 phosphoserine phosphatase activity - - - 1.633e-271 859.0
CH2_k127_6593596_2 cell division K09811,K09812 GO:0005575,GO:0005618,GO:0005623,GO:0006928,GO:0008150,GO:0009274,GO:0009276,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0030312,GO:0030313,GO:0031975,GO:0040011,GO:0043207,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051301,GO:0051674,GO:0051704,GO:0051707,GO:0071944,GO:0071976 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 360.0
CH2_k127_6593596_3 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 340.0
CH2_k127_6593596_5 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000104 211.0
CH2_k127_6593596_6 phosphorelay signal transduction system - - - 0.00000000000000000000000000151 114.0
CH2_k127_6593596_8 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000028 63.0
CH2_k127_6615000_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0 1047.0
CH2_k127_6615000_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.861e-195 623.0
CH2_k127_6615000_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 482.0
CH2_k127_6615000_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 413.0
CH2_k127_6615000_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002042 271.0
CH2_k127_6615000_5 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000002005 219.0
CH2_k127_6615000_6 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000006659 195.0
CH2_k127_6615000_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000008133 149.0
CH2_k127_6615000_8 electron transfer activity K05337 - - 0.0000000000000000001469 101.0
CH2_k127_667461_0 ABC transporter K02017 - 3.6.3.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 334.0
CH2_k127_667461_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 315.0
CH2_k127_667461_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000001469 211.0
CH2_k127_667461_3 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000004491 202.0
CH2_k127_6717315_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 503.0
CH2_k127_6717315_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 372.0
CH2_k127_6717315_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 341.0
CH2_k127_6759203_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 606.0
CH2_k127_6759203_1 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 467.0
CH2_k127_6759203_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 308.0
CH2_k127_6759203_3 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001277 267.0
CH2_k127_6759203_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000001208 225.0
CH2_k127_6759203_5 ATPase activity K01990,K01992,K13926 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015562,GO:0015893,GO:0016020,GO:0022857,GO:0042221,GO:0042493,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000492 212.0
CH2_k127_6759203_6 preribosome binding K07574 GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - 0.000000000000000000000000000000000000008622 157.0
CH2_k127_6759203_7 IgA Peptidase M64 - - - 0.0000000000000000000000059 104.0
CH2_k127_6759203_8 HlyD family secretion protein K01993 - - 0.0000001749 55.0
CH2_k127_6771498_0 Transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 398.0
CH2_k127_6771498_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 348.0
CH2_k127_6771498_2 Major intrinsic protein K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 331.0
CH2_k127_6771498_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 284.0
CH2_k127_6827036_0 protocatechuate 3,4-dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 388.0
CH2_k127_6827036_1 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000009062 193.0
CH2_k127_6827036_2 Phospholipid methyltransferase - - - 0.0000000000000000007561 89.0
CH2_k127_6827036_3 - - - - 0.00003361 54.0
CH2_k127_6839674_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 325.0
CH2_k127_6839674_1 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002081 261.0
CH2_k127_6839674_2 Ferritin-like domain K04047 - - 0.00000000000000000000000000000000000000000000000000000000174 203.0
CH2_k127_6839674_4 Sigma-54 interaction domain K15836 - - 0.00000000000000000000000000000000000000000000000008993 180.0
CH2_k127_6839674_5 Major Facilitator Superfamily - - - 0.000000000002142 68.0
CH2_k127_6941462_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000002044 189.0
CH2_k127_6970657_0 L-malate dehydrogenase activity K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0030312,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 559.0
CH2_k127_6970657_1 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000000008171 186.0
CH2_k127_6970657_2 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000002197 158.0
CH2_k127_6970657_4 PFAM Radical SAM superfamily - - - 0.0000007096 59.0
CH2_k127_6970657_5 peptidase S8 and S53, subtilisin, kexin, sedolisin K14645 - - 0.0000892 53.0
CH2_k127_6996845_0 Tricorn protease homolog - - - 0.0 1580.0
CH2_k127_6996845_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000307 258.0
CH2_k127_6996845_2 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000004485 205.0
CH2_k127_6996845_3 Domains in Na-Ca exchangers and integrin-beta4 K01406 - 3.4.24.40 0.0000000000000000000000000000000001492 151.0
CH2_k127_7016180_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 370.0
CH2_k127_7016180_1 RecQ zinc-binding K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000002113 227.0
CH2_k127_7016180_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000006388 199.0
CH2_k127_7039820_0 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000009513 228.0
CH2_k127_7039820_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000006286 200.0
CH2_k127_7039820_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000947 112.0
CH2_k127_7045583_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0 1631.0
CH2_k127_7045583_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 321.0
CH2_k127_7045583_2 Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K20534 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000002589 227.0
CH2_k127_7045583_3 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000001036 229.0
CH2_k127_7045583_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000491 90.0
CH2_k127_7045583_6 - - - - 0.000027 57.0
CH2_k127_706082_0 Nitrite and sulphite reductase 4Fe-4S K00381,K00392 - 1.8.1.2,1.8.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 412.0
CH2_k127_706082_1 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 365.0
CH2_k127_706082_2 Belongs to the PAPS reductase family. CysH subfamily K00366,K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.7.7.1,1.8.4.10,1.8.4.8,2.7.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 296.0
CH2_k127_706082_3 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000299 229.0
CH2_k127_7088229_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.704e-300 932.0
CH2_k127_7088229_1 Belongs to the thiolase family - - - 0.0000000000000000000000000000000000000000000000000009679 184.0
CH2_k127_7097533_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1818.0
CH2_k127_7097533_1 acetyltransferase K03828 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006564 243.0
CH2_k127_7097533_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000000009962 196.0
CH2_k127_7097533_4 efflux transmembrane transporter activity - - - 0.00004938 56.0
CH2_k127_7141551_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 582.0
CH2_k127_7141551_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 457.0
CH2_k127_7141551_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 306.0
CH2_k127_7141551_3 Redoxin K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000004541 228.0
CH2_k127_718621_0 Cache 3/Cache 2 fusion domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 484.0
CH2_k127_718621_1 TIGRFAM methionine-R-sulfoxide reductase K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000001162 241.0
CH2_k127_718621_2 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000002249 131.0
CH2_k127_7187992_0 cobalamin-transporting ATPase activity K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001065 277.0
CH2_k127_7187992_1 abc-type fe3 -hydroxamate transport system, periplasmic component K02016,K16092 - - 0.00000000000000000000000000000000000000003077 158.0
CH2_k127_7192666_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 8.666e-288 900.0
CH2_k127_7192666_1 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000009045 95.0
CH2_k127_7210434_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 590.0
CH2_k127_7210434_1 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 409.0
CH2_k127_7210434_2 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 387.0
CH2_k127_7210434_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000003328 117.0
CH2_k127_7217436_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1040.0
CH2_k127_7217436_1 Beta-eliminating lyase K01667 - 4.1.99.1 2.231e-237 740.0
CH2_k127_7217436_2 polysaccharide deacetylase K13014 GO:0005575,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0042221,GO:0050896 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 508.0
CH2_k127_7217436_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 362.0
CH2_k127_7217436_4 Acetyltransferase (GNAT) domain K03829 - - 0.00000000000000000000000000000000000000000000000000000000000002893 226.0
CH2_k127_7217436_7 - - - - 0.000000000000001379 80.0
CH2_k127_7217436_8 protein kinase activity - - - 0.000000005217 64.0
CH2_k127_7217436_9 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000007859 57.0
CH2_k127_7235539_0 Bacterial protein of unknown function (DUF853) - - - 6.688e-226 710.0
CH2_k127_7235539_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.315e-206 644.0
CH2_k127_7235539_2 Haemolytic K08998 - - 0.000000000000000000000000000000002604 134.0
CH2_k127_7266060_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 477.0
CH2_k127_7266060_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 324.0
CH2_k127_7270624_0 dihydroxy-acid dehydratase activity K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 287.0
CH2_k127_7270624_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000001545 246.0
CH2_k127_7274853_0 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 503.0
CH2_k127_7274853_1 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 501.0
CH2_k127_7274853_2 LysR substrate binding domain K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 373.0
CH2_k127_7274853_3 energy transducer activity K03646,K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 327.0
CH2_k127_7274853_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000001098 229.0
CH2_k127_7274853_5 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000000000000000000000000003854 204.0
CH2_k127_7274853_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000005144 158.0
CH2_k127_7274853_7 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.000000000000000000232 91.0
CH2_k127_7293460_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1326.0
CH2_k127_7293460_1 nitrite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 541.0
CH2_k127_7293460_2 Transporter K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 496.0
CH2_k127_7293460_3 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 462.0
CH2_k127_7293460_4 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 355.0
CH2_k127_7293460_5 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003436 239.0
CH2_k127_7293460_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000008804 248.0
CH2_k127_7293460_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000001645 198.0
CH2_k127_7293460_9 Carboxymuconolactone decarboxylase family - - - 0.000001383 55.0
CH2_k127_7324036_0 PFAM peptidase S49 K04773 - - 1.733e-226 718.0
CH2_k127_7324036_1 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 442.0
CH2_k127_7324036_2 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001958 271.0
CH2_k127_7324036_3 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000004996 237.0
CH2_k127_7324036_4 Disulphide isomerase - - - 0.00000000000000000000000000000000000000000000000009815 194.0
CH2_k127_7324036_6 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000001411 58.0
CH2_k127_7330888_0 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 475.0
CH2_k127_7330888_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 338.0
CH2_k127_7346428_0 Pyridine nucleotide-disulphide oxidoreductase K00266,K00528,K17722 - 1.18.1.2,1.19.1.1,1.3.1.1,1.4.1.13,1.4.1.14 0.0 1499.0
CH2_k127_7346428_1 dihydroorotate dehydrogenase activity K00254,K02823,K17828 - 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 501.0
CH2_k127_7346428_2 Coenzyme A transferase K01029 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 381.0
CH2_k127_7346428_3 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003295 279.0
CH2_k127_7346428_4 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000003356 223.0
CH2_k127_7346428_5 - K09858 - - 0.000000000000000000000000000000000000000000000000004757 183.0
CH2_k127_7346428_7 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000004826 140.0
CH2_k127_7369318_0 Secretin and TonB N terminus short domain K02666 - - 4.136e-215 689.0
CH2_k127_7369318_1 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 437.0
CH2_k127_7369318_2 carbon utilization K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000001877 238.0
CH2_k127_7369318_3 PFAM Fimbrial assembly family protein K02461,K02662,K02663,K12279,K12289 GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000002693 236.0
CH2_k127_7383488_0 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 336.0
CH2_k127_7383488_1 pfam abc K02032 - - 0.000000000000000000000000000000000001447 145.0
CH2_k127_7385055_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1145.0
CH2_k127_7385055_1 phytanoyl-CoA dioxygenase - - - 0.000000000000000000000000000000000000001676 153.0
CH2_k127_7419111_0 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 610.0
CH2_k127_7419111_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 587.0
CH2_k127_7419111_3 pfam abc K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 440.0
CH2_k127_7419111_4 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 402.0
CH2_k127_7419111_5 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K04040,K20616 - 2.5.1.133,2.5.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 385.0
CH2_k127_7419111_6 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005555 332.0
CH2_k127_7419111_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 289.0
CH2_k127_7419111_8 branched-chain-amino-acid transaminase activity K02619 - 4.1.3.38 0.000000000000000000000000000000000000000000000398 171.0
CH2_k127_7458754_0 protein histidine kinase activity K03407,K07678 - 2.7.13.3 6.396e-216 687.0
CH2_k127_7458754_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 564.0
CH2_k127_7458754_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 477.0
CH2_k127_7458754_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 449.0
CH2_k127_7458754_4 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000000000000000000009084 196.0
CH2_k127_7458754_5 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000001652 190.0
CH2_k127_7458754_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000591 94.0
CH2_k127_7464605_0 TIGRFAM delta-1-pyrroline-5-carboxylate dehydrogenase, group 1 K00294,K13821 - 1.2.1.88,1.5.5.2 5.756e-231 726.0
CH2_k127_7464605_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.903e-228 717.0
CH2_k127_7464605_2 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 610.0
CH2_k127_7464605_3 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008801 427.0
CH2_k127_7464605_4 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 334.0
CH2_k127_7464605_5 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000004611 220.0
CH2_k127_7464605_6 regulation of translation K03530 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000004287 158.0
CH2_k127_7464605_7 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000001092 162.0
CH2_k127_7464605_8 RDD family - - - 0.00000000000000000000000001944 115.0
CH2_k127_7500177_0 Cys Met metabolism - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 575.0
CH2_k127_7500177_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 407.0
CH2_k127_7500177_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 332.0
CH2_k127_7500177_3 Threonine/Serine exporter, ThrE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005303 283.0
CH2_k127_7500177_4 sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000000000000002262 193.0
CH2_k127_7500177_5 CDGSH-type zinc finger. Function unknown. - - - 0.000000000000000000000000000000000000000000004383 175.0
CH2_k127_7515019_0 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 336.0
CH2_k127_7515019_1 Voltage gated chloride channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005005 280.0
CH2_k127_7515019_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004946 266.0
CH2_k127_7515019_3 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000005254 217.0
CH2_k127_7515019_4 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000001643 109.0
CH2_k127_7516063_0 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 9.357e-237 754.0
CH2_k127_7516063_1 phosphate transport system permease protein K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 571.0
CH2_k127_7516063_2 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 472.0
CH2_k127_7516063_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 426.0
CH2_k127_7516063_4 Two component transcriptional regulator, winged helix family K07776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 326.0
CH2_k127_7516063_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 296.0
CH2_k127_7516063_6 Ribonuclease, Rne Rng family - - - 0.00000000000000000000000000000000000000000000000003556 183.0
CH2_k127_7516063_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000001025 65.0
CH2_k127_7544989_0 PFAM Integral membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 487.0
CH2_k127_7544989_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 477.0
CH2_k127_7544989_2 MOSC domain - - - 0.000000000000000000000000000000001635 134.0
CH2_k127_7561224_0 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 582.0
CH2_k127_7561224_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 464.0
CH2_k127_7561224_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000208 267.0
CH2_k127_7561224_4 thiamine-phosphate diphosphorylase activity K00788 - 2.5.1.3 0.0000001181 54.0
CH2_k127_7561224_5 repeat-containing protein - - - 0.00006582 50.0
CH2_k127_7566807_0 Proline racemase K12658 - 5.1.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 517.0
CH2_k127_7566807_1 PFAM FAD dependent oxidoreductase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 329.0
CH2_k127_7566807_2 FCD - - - 0.00000000000003623 74.0
CH2_k127_7582495_0 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 378.0
CH2_k127_7582495_1 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 351.0
CH2_k127_7582495_2 Domain of unknown function (DUF4154) - - - 0.0000000000000000000000001109 113.0
CH2_k127_7587718_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000004661 196.0
CH2_k127_7587718_2 photosynthesis - - - 0.000000000000000000000000000000000000000000004839 175.0
CH2_k127_7615122_0 Ribosomal protein S1 K02945 - - 0.0 1005.0
CH2_k127_7615122_1 PFAM Gamma-glutamyltranspeptidase - - - 3.367e-198 629.0
CH2_k127_7657261_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0 1008.0
CH2_k127_7657261_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 469.0
CH2_k127_7657261_2 wobble position uridine ribose methylation K03216 GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002024 268.0
CH2_k127_7657261_3 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005506 262.0
CH2_k127_7657261_4 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000001517 237.0
CH2_k127_7657261_5 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000008379 168.0
CH2_k127_7657261_8 GTP binding K06883 - - 0.0000000000000000134 86.0
CH2_k127_7657261_9 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000006076 68.0
CH2_k127_7662990_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 8.179e-279 875.0
CH2_k127_7662990_1 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000004384 244.0
CH2_k127_7662990_2 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.0000000000000000003253 97.0
CH2_k127_7683021_0 PFAM Glycosyl transferase, family K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 592.0
CH2_k127_7683021_1 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 454.0
CH2_k127_7683021_2 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 359.0
CH2_k127_7683021_4 Glutaredoxin - - - 0.00000000000000000000000000000000001303 140.0
CH2_k127_7683021_5 Thioredoxin - - - 0.000002289 59.0
CH2_k127_7700526_0 PFAM aminotransferase class V K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 497.0
CH2_k127_7700526_1 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 370.0
CH2_k127_7700526_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000006125 222.0
CH2_k127_7700526_3 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000007533 177.0
CH2_k127_7703692_0 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007222 280.0
CH2_k127_7703692_1 Formate nitrite K06212 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001704 280.0
CH2_k127_7703692_2 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000000000000000000000000886 209.0
CH2_k127_7703692_3 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000002346 127.0
CH2_k127_7706357_0 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 371.0
CH2_k127_7706357_1 COG0480 Translation elongation factors (GTPases) K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 317.0
CH2_k127_7706357_2 - - - - 0.0000000000000000000000000000000000000000002183 162.0
CH2_k127_7741304_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.000000000000000000000000000000000003578 138.0
CH2_k127_7762373_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 377.0
CH2_k127_7762373_1 tail specific protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 334.0
CH2_k127_7762373_2 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001665 256.0
CH2_k127_7762373_3 - - - - 0.000000000000000000000000000000000006239 148.0
CH2_k127_7762373_4 Transcriptional regulator, AsnC family - - - 0.00000000000000000000000000002108 123.0
CH2_k127_7790153_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 2.077e-299 933.0
CH2_k127_7790153_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 425.0
CH2_k127_7790153_2 Belongs to the UPF0354 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000033 281.0
CH2_k127_7790153_5 DinB family - - - 0.0001873 50.0
CH2_k127_7819861_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0 1146.0
CH2_k127_7819861_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 595.0
CH2_k127_7819861_2 PFAM Adenosine AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 555.0
CH2_k127_7819861_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000905 456.0
CH2_k127_7819861_4 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 376.0
CH2_k127_7819861_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 346.0
CH2_k127_7819861_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000005173 210.0
CH2_k127_7819861_7 rRNA processing K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000004025 187.0
CH2_k127_7819861_8 PFAM Adenosine AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.000000000001344 69.0
CH2_k127_7831282_0 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 521.0
CH2_k127_7831282_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000006126 189.0
CH2_k127_7831319_0 nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 3.304e-264 820.0
CH2_k127_7831319_1 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000564 591.0
CH2_k127_7831319_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003597 259.0
CH2_k127_7831319_3 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000001754 236.0
CH2_k127_7831319_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0042126,GO:0043436,GO:0043546,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0097159,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.00000000000000000000000000000000000000000000000000000008733 195.0
CH2_k127_7831319_5 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000000000000000000006281 154.0
CH2_k127_7831319_6 nitrate reductase activity K00370,K00374,K02575 GO:0001666,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006950,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009628,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0036293,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0055114,GO:0070469,GO:0070470,GO:0070482,GO:0071944,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 1.7.5.1 0.000000009758 59.0
CH2_k127_7851078_0 Heat shock 70 kDa protein - - - 0.0 1064.0
CH2_k127_7851078_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 473.0
CH2_k127_7851078_2 PFAM regulatory protein, MerR K13640 - - 0.00000000000000000000000000000000000000000000000107 191.0
CH2_k127_7851078_3 zinc ion binding K00859,K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 2.7.1.24 0.0000000000000000000000463 100.0
CH2_k127_7851078_4 Exopolysaccharide synthesis, ExoD - - - 0.0000000000000000002644 95.0
CH2_k127_7851078_5 Carbohydrate binding domain X2 - - - 0.00000000000000004891 85.0
CH2_k127_7864159_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 1.055e-234 733.0
CH2_k127_7864159_1 Zinc metalloprotease (Elastase) K08603,K20273 - 3.4.24.27 6.869e-229 742.0
CH2_k127_7864159_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.491e-218 684.0
CH2_k127_7864159_3 Amidinotransferase K01478 - 3.5.3.6 1.618e-218 685.0
CH2_k127_7864159_4 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 493.0
CH2_k127_7864159_5 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 458.0
CH2_k127_7864159_6 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009762 342.0
CH2_k127_7864159_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000004891 229.0
CH2_k127_7864159_8 competence protein - GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000001359 98.0
CH2_k127_7864159_9 Di-iron-containing protein involved in the repair of iron-sulfur clusters - - - 0.00000000000000006725 89.0
CH2_k127_7876249_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 537.0
CH2_k127_7876249_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 356.0
CH2_k127_7876249_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 316.0
CH2_k127_7876249_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 324.0
CH2_k127_7876249_4 diguanylate cyclase K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00000000000000001036 91.0
CH2_k127_7876249_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000001344 63.0
CH2_k127_7908917_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 4.087e-280 878.0
CH2_k127_7908917_1 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 1.035e-220 707.0
CH2_k127_7908917_2 PFAM Outer membrane efflux protein - - - 0.0001542 50.0
CH2_k127_793254_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.975e-246 770.0
CH2_k127_793254_1 response to hydroperoxide K09861 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 307.0
CH2_k127_793254_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001137 254.0
CH2_k127_7961854_0 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 505.0
CH2_k127_7961854_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 505.0
CH2_k127_7961854_2 Phosphofructokinase K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 472.0
CH2_k127_7961854_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002247 252.0
CH2_k127_7961854_4 Cupin 2, conserved barrel domain protein K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000001116 199.0
CH2_k127_7961854_5 Protein of unknown function (DUF418) K07148 - - 0.000000000004607 66.0
CH2_k127_7980116_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 501.0
CH2_k127_7980116_1 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001539 286.0
CH2_k127_7980116_2 Cobalamin adenosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005186 259.0
CH2_k127_7980116_3 TIGRFAM glutamate formiminotransferase K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000003704 53.0
CH2_k127_7985420_0 Belongs to the GARS family K01945 - 6.3.4.13 1.025e-195 619.0
CH2_k127_7985420_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.0000000000000000000000000000000000000000000008783 182.0
CH2_k127_7985420_2 cAMP biosynthetic process - - - 0.00000000000000000000000000004732 121.0
CH2_k127_7998156_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 441.0
CH2_k127_7998156_1 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 340.0
CH2_k127_8039986_0 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 394.0
CH2_k127_8039986_1 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 393.0
CH2_k127_8039986_2 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 381.0
CH2_k127_8039986_3 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000001013 271.0
CH2_k127_8052804_0 PFAM FAD linked oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 528.0
CH2_k127_8052804_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 338.0
CH2_k127_8052804_2 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 311.0
CH2_k127_8052804_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005856 278.0
CH2_k127_8052804_4 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006589 244.0
CH2_k127_8052804_5 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000218 194.0
CH2_k127_8053184_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 426.0
CH2_k127_8053184_1 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 351.0
CH2_k127_8066645_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 351.0
CH2_k127_8066645_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000001781 69.0
CH2_k127_8150011_0 DEAD DEAH box helicase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 590.0
CH2_k127_8150011_1 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 434.0
CH2_k127_8150011_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 419.0
CH2_k127_8150011_3 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000003802 269.0
CH2_k127_8150011_4 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000009572 225.0
CH2_k127_8150011_5 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000000000000000000005059 191.0
CH2_k127_8150011_6 - - - - 0.00000000000000000000000004347 118.0
CH2_k127_8152564_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 617.0
CH2_k127_8152564_1 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.0000000000000000000000000000000000000000000000002857 185.0
CH2_k127_8152564_2 Protein of unknown function DUF58 - - - 0.0000000000000152 75.0
CH2_k127_8189804_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002621 278.0
CH2_k127_8189988_0 Zinc carboxypeptidase - - - 2.349e-202 644.0
CH2_k127_8189988_1 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 449.0
CH2_k127_8257798_0 regulation of single-species biofilm formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008066 286.0
CH2_k127_8257798_3 Dihydropyrimidinase K01464 - 3.5.2.2 0.00000000000000000000001179 111.0
CH2_k127_8257798_4 von Willebrand factor type A K07114 - - 0.000000003995 61.0
CH2_k127_8257798_5 Putative bacterial sensory transduction regulator - - - 0.00000007064 64.0
CH2_k127_828343_0 lyase activity K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 510.0
CH2_k127_828343_1 Thiolase, C-terminal domain K00626,K07508 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 353.0
CH2_k127_8301819_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 520.0
CH2_k127_8301819_1 mRNA catabolic process K06950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 367.0
CH2_k127_8301819_2 deoxyhypusine monooxygenase activity - - - 0.00000003698 66.0
CH2_k127_8324937_0 lysine biosynthetic process via aminoadipic acid - - - 1.176e-307 964.0
CH2_k127_8324937_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 403.0
CH2_k127_8324937_2 Uncharacterized ACR, COG1430 - - - 0.000000000000000000000000000000000000000000000000000000000000000006658 229.0
CH2_k127_8328566_0 mRNA catabolic process K18682 - - 6.899e-246 769.0
CH2_k127_8328566_1 COG4771 Outer membrane receptor for ferrienterochelin and colicins K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 460.0
CH2_k127_8328566_2 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 391.0
CH2_k127_8328566_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 415.0
CH2_k127_8328566_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000006445 153.0
CH2_k127_8332585_0 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 325.0
CH2_k127_8332585_1 DNA (cytosine-5-)-methyltransferase activity K00558 - 2.1.1.37 0.00000000000000000000000000000000000000000000000000009736 191.0
CH2_k127_8332585_10 Belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.0004809 47.0
CH2_k127_8332585_2 Kelch-like protein 17 K10454 GO:0000151,GO:0003674,GO:0003779,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006996,GO:0007010,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008092,GO:0008150,GO:0009987,GO:0014069,GO:0015629,GO:0016043,GO:0019904,GO:0030029,GO:0030036,GO:0030425,GO:0031208,GO:0031461,GO:0031463,GO:0032279,GO:0032501,GO:0032502,GO:0032838,GO:0032839,GO:0032947,GO:0032991,GO:0036477,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044297,GO:0044424,GO:0044444,GO:0044456,GO:0044463,GO:0044464,GO:0044877,GO:0045202,GO:0048513,GO:0048731,GO:0048856,GO:0051015,GO:0060322,GO:0071840,GO:0097447,GO:0097458,GO:0098794,GO:0098984,GO:0099568,GO:0099572,GO:0120025,GO:0120038,GO:0120111,GO:1902494,GO:1990234 - 0.000000000000000000000000000000000000000000000000003021 195.0
CH2_k127_8332585_3 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000000000222 188.0
CH2_k127_8332585_4 Domain of unknown function (DUF4397) - - - 0.000000000000000000000000002809 120.0
CH2_k127_8332585_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000001061 113.0
CH2_k127_8332585_6 COG3806 Anti-sigma factor K07167 - - 0.0000000000000000000000003783 115.0
CH2_k127_8332585_7 cation diffusion facilitator family transporter K16264 - - 0.00000009795 59.0
CH2_k127_8332585_8 cation diffusion facilitator family transporter K16264 - - 0.0000001271 55.0
CH2_k127_8332585_9 beta-galactosidase activity - - - 0.00001041 57.0
CH2_k127_8335760_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 548.0
CH2_k127_8335760_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 358.0
CH2_k127_8335760_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005927 246.0
CH2_k127_8335760_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000000001535 222.0
CH2_k127_8335760_4 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000001282 115.0
CH2_k127_8335760_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000001125 103.0
CH2_k127_8335760_6 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000004241 69.0
CH2_k127_8370257_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 3.434e-254 790.0
CH2_k127_8370257_1 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000001901 243.0
CH2_k127_8370257_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000000000000000000000001509 164.0
CH2_k127_8376252_0 TIGRFAM ornithine aminotransferase K00819 - 2.6.1.13 5.948e-222 693.0
CH2_k127_8376252_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 617.0
CH2_k127_8376252_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 497.0
CH2_k127_8376252_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 319.0
CH2_k127_8376252_4 beta-lactamase activity K07126 - - 0.0000000000000000000000000000000000005472 154.0
CH2_k127_8380490_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 490.0
CH2_k127_8380490_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001037 157.0
CH2_k127_8399303_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 612.0
CH2_k127_8399303_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 396.0
CH2_k127_8399303_2 phosphorelay signal transduction system K10941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 354.0
CH2_k127_8399303_3 Pfam Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000007205 232.0
CH2_k127_8413964_0 Vitamin B12 dependent methionine synthase, activation domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000003368 256.0
CH2_k127_8413964_1 Transcriptional regulator, LysR - - - 0.000000000000000000000000000000000000000000000000000004335 201.0
CH2_k127_8425244_0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003222 276.0
CH2_k127_8425244_1 BMC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009293 249.0
CH2_k127_8425244_2 COGs COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein K04027 - - 0.00000000000000000000000000000000000009949 144.0
CH2_k127_8425244_3 TIGRFAM sugar-phosphate isomerase, RpiB LacA LacB family K01808 - 5.3.1.6 0.000000002081 59.0
CH2_k127_8425244_4 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.00000001656 56.0
CH2_k127_8457603_0 Sortilin, neurotensin receptor 3, - - - 0.0 1111.0
CH2_k127_8457603_1 peptidase activity, acting on L-amino acid peptides K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 513.0
CH2_k127_8457603_2 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 382.0
CH2_k127_8457603_3 domain, Protein K07654 - 2.7.13.3 0.00000000000007653 87.0
CH2_k127_8467106_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1030.0
CH2_k127_8467106_1 PFAM Glycosyl transferase family 2 - - - 5.101e-280 883.0
CH2_k127_8467106_2 protein kinase activity - - - 3.347e-206 659.0
CH2_k127_8467106_3 nucleotide catabolic process K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 409.0
CH2_k127_8467106_4 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 370.0
CH2_k127_8467106_5 tRNA pseudouridine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 340.0
CH2_k127_8467106_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 324.0
CH2_k127_8467106_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000005143 209.0
CH2_k127_8467106_8 Response regulator, receiver K10715 - 2.7.13.3 0.00000000000000000000000000000000000000002349 159.0
CH2_k127_8517400_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005794 596.0
CH2_k127_8517400_1 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002002 283.0
CH2_k127_8517400_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000005114 218.0
CH2_k127_8517400_4 nuclear chromosome segregation - - - 0.0000000000000000001844 101.0
CH2_k127_8523283_0 Aconitase family (aconitate hydratase) - - - 0.0 1257.0
CH2_k127_8523283_1 SMART Elongator protein 3 MiaB NifB - - - 1.207e-211 673.0
CH2_k127_8523283_2 COG0659 Sulfate permease and related transporters (MFS superfamily) K01673,K03321 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 550.0
CH2_k127_8523283_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009735 265.0
CH2_k127_8523283_4 NusB family K03625 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001313 261.0
CH2_k127_8523283_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000004102 78.0
CH2_k127_8538116_1 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 467.0
CH2_k127_8538116_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 398.0
CH2_k127_8538116_3 PFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K07443 - - 0.0000000000000000000000000000000000000000000006126 179.0
CH2_k127_8538116_4 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000000000000004141 166.0
CH2_k127_8538116_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01923,K01952 - 6.3.2.6,6.3.5.3 0.00000000000000000000000000001205 119.0
CH2_k127_8539376_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.462e-211 663.0
CH2_k127_8539376_1 light absorption K01822 - 5.3.3.1 0.0000000000000000002057 94.0
CH2_k127_8557522_0 SMART Resolvase, RNase H domain protein fold K06959 - - 0.0 1104.0
CH2_k127_8557522_1 formyl-CoA transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 554.0
CH2_k127_8557827_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 2.843e-281 871.0
CH2_k127_8557827_1 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 9.719e-241 749.0
CH2_k127_8557827_2 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 487.0
CH2_k127_8557827_3 denitrification pathway K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 285.0
CH2_k127_8557827_4 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000005958 265.0
CH2_k127_8557827_5 Belongs to the bacterial histone-like protein family K03530 - - 0.000000000000000000000000000000000000000000008262 163.0
CH2_k127_8562428_0 PFAM EAL domain K21023 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 548.0
CH2_k127_8562428_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 396.0
CH2_k127_8577088_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1084.0
CH2_k127_8642338_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604,K10011 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 391.0
CH2_k127_8642338_1 photosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 304.0
CH2_k127_8695347_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 324.0
CH2_k127_8695347_1 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00000000000000000000000000000000000000000000000000000000000000000007422 243.0
CH2_k127_8695347_2 Uncharacterized protein family UPF0029 K00560,K01271 - 2.1.1.45,3.4.13.9 0.00000000000000000000000000000000000002777 145.0
CH2_k127_8695347_3 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00000001066 61.0
CH2_k127_8697516_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1050.0
CH2_k127_8697516_1 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 8.645e-194 620.0
CH2_k127_8697516_2 MoeZ MoeB domain K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 569.0
CH2_k127_8697516_4 alpha-ribazole phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003657 269.0
CH2_k127_8697516_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000163 235.0
CH2_k127_8697516_7 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000008774 198.0
CH2_k127_8697516_9 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000886 48.0
CH2_k127_8707883_0 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009933 259.0
CH2_k127_8707883_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000277 229.0
CH2_k127_8707883_2 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.0000000000000000000000000000000000007718 158.0
CH2_k127_8707883_3 cell adhesion involved in biofilm formation - - - 0.0000003328 58.0
CH2_k127_8748717_0 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 372.0
CH2_k127_8748717_1 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 360.0
CH2_k127_8748717_2 Roadblock/LC7 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001033 270.0
CH2_k127_8748717_3 YjbR - - - 0.000000000000000000000000000001614 130.0
CH2_k127_8771367_0 TIGRFAM MazG family protein K02428,K02499,K04765 - 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 416.0
CH2_k127_8771367_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000001968 153.0
CH2_k127_8773631_0 protein serine/threonine kinase activity K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 438.0
CH2_k127_8773631_1 Major facilitator Superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 414.0
CH2_k127_8773631_2 phosphorelay sensor kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 380.0
CH2_k127_8773631_3 Acetyltransferase (GNAT) domain - - - 0.00000000000005938 78.0
CH2_k127_8790915_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 471.0
CH2_k127_8790915_1 CoA-binding domain protein - - - 0.0000000000000000000000000000000000000001761 158.0
CH2_k127_8818736_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 8.355e-195 613.0
CH2_k127_8818736_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 600.0
CH2_k127_8818736_2 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 449.0
CH2_k127_8818736_3 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 412.0
CH2_k127_8818736_4 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000001029 212.0
CH2_k127_8818736_5 Chorismate mutase K00210,K04092,K04093,K14187 GO:0000166,GO:0003674,GO:0003824,GO:0004106,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,5.4.99.5 0.0000000000000000916 83.0
CH2_k127_883583_0 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 544.0
CH2_k127_883583_1 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000004164 258.0
CH2_k127_883583_2 Tellurite resistance protein TerB - - - 0.00000234 50.0
CH2_k127_8907448_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007215 503.0
CH2_k127_8907448_1 pseudouridine synthase activity K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 301.0
CH2_k127_8907448_2 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002223 256.0
CH2_k127_8917836_0 aminotransferase K14287 - 2.6.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 428.0
CH2_k127_8917836_1 Penicillinase repressor - - - 0.000000000000000000000000000000000000002258 150.0
CH2_k127_8923217_0 PFAM Acetyl-CoA dehydrogenase-like C-terminal domain, Acyl-CoA dehydrogenase domain-containing protein, acyl-CoA dehydrogenase domain-containing protein K09456 - - 1.904e-270 844.0
CH2_k127_8923217_1 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00632 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 557.0
CH2_k127_8923217_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008903 418.0
CH2_k127_8929628_0 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 548.0
CH2_k127_8929764_0 PFAM peptidase M13 K07386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 530.0
CH2_k127_8929764_1 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.00000000000000000003779 92.0
CH2_k127_8929764_2 glycosyl transferase family 2 - - - 0.00000000000000000007915 101.0
CH2_k127_8949184_0 MarC family integral membrane protein K05595 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 322.0
CH2_k127_8949184_1 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 321.0
CH2_k127_8949184_2 Aspartyl/Asparaginyl beta-hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001698 268.0
CH2_k127_8949184_3 PFAM Stage II sporulation protein E (SpoIIE) - - - 0.000000000000000000000000000000000000000000000000000001049 208.0
CH2_k127_8949184_4 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000000000000001752 145.0
CH2_k127_8949184_5 transposase - - - 0.00003657 46.0
CH2_k127_8953912_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 8.541e-265 835.0
CH2_k127_8953912_1 Amino acid permease - - - 2.996e-256 807.0
CH2_k127_8953912_2 Elongator protein 3, MiaB family, Radical SAM K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 513.0
CH2_k127_8953912_3 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 384.0
CH2_k127_8953912_4 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000002584 216.0
CH2_k127_8953912_5 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000004992 219.0
CH2_k127_8953912_6 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K13483,K20446 - 1.17.1.5,1.2.5.3 0.00000000000000000000000000000000000000000000000000000003554 200.0
CH2_k127_8953912_7 Putative DNA-binding domain K09929 - - 0.000000000000000000000000000000000000000000006524 181.0
CH2_k127_8953912_8 Putative inner membrane exporter, YdcZ K09936 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000002664 111.0
CH2_k127_8953912_9 Amino acid permease - - - 0.0000000000000003914 79.0
CH2_k127_8968285_0 Dienelactone hydrolase family - - - 0.0 1298.0
CH2_k127_8968285_1 synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 529.0
CH2_k127_8968285_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 477.0
CH2_k127_8968285_3 methyltransferase K03183,K21600 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 305.0
CH2_k127_8968285_5 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000000000004024 194.0
CH2_k127_8968285_6 - - - - 0.0000000000000000000000000000003883 132.0
CH2_k127_8974077_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 469.0
CH2_k127_8974077_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008553 432.0
CH2_k127_8996169_0 amine dehydrogenase activity - - - 2.578e-224 729.0
CH2_k127_8996169_1 Protease prsW family - - - 0.00000000000002284 77.0
CH2_k127_8996912_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 2.127e-232 726.0
CH2_k127_8996912_1 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 551.0
CH2_k127_8996912_2 Kelch - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 337.0
CH2_k127_8996912_3 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0006059 53.0
CH2_k127_9040844_0 PFAM Mammalian cell entry related domain protein K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 475.0
CH2_k127_9040844_1 paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000001239 207.0
CH2_k127_9040844_2 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000007245 63.0
CH2_k127_9048460_0 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 601.0
CH2_k127_9048460_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 564.0
CH2_k127_9048460_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 397.0
CH2_k127_9048460_3 ABC transporter transmembrane K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 333.0
CH2_k127_9048460_5 NYN domain - - - 0.0001277 49.0
CH2_k127_9098138_0 metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000005976 205.0
CH2_k127_9098138_1 CbbQ/NirQ/NorQ C-terminal K09882 - 6.6.1.2 0.00000000000000000000000000000000000000000000005088 188.0
CH2_k127_9098138_3 PFAM von Willebrand factor type A - - - 0.00000498 59.0
CH2_k127_9103334_0 glycosyl transferase group 1 K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 600.0
CH2_k127_9103334_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000000001336 209.0
CH2_k127_9103334_2 Uncharacterized protein family UPF0029 K00560,K01271 - 2.1.1.45,3.4.13.9 0.0000000000000000000000006057 105.0
CH2_k127_9153746_0 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 354.0
CH2_k127_9153746_1 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008039 259.0
CH2_k127_9153746_2 cdp-diacylglycerol--glycerol-3-phosphate - - - 0.0000000000000000000000000000000000000003846 153.0
CH2_k127_9153746_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604,K10011 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006040,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0022607,GO:0033319,GO:0033320,GO:0034214,GO:0034641,GO:0034654,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046349,GO:0046483,GO:0046677,GO:0048037,GO:0048040,GO:0050662,GO:0050896,GO:0051259,GO:0051287,GO:0055086,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:0099618,GO:0099619,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:2001313,GO:2001315 1.1.1.305,2.1.2.13,2.1.2.9 0.00003331 46.0
CH2_k127_9156897_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1397.0
CH2_k127_9156897_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1238.0
CH2_k127_9156897_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000001181 231.0
CH2_k127_9182592_0 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 6.734e-251 788.0
CH2_k127_9182592_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 400.0
CH2_k127_9182592_2 Rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001627 248.0
CH2_k127_9187671_1 Cytochrome C and Quinol oxidase polypeptide I K00404 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 419.0
CH2_k127_9187671_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000006077 141.0
CH2_k127_9187671_3 COG1290 Cytochrome b subunit of the bc complex K00412 - - 0.000000000000000000000000000001764 138.0
CH2_k127_9187671_4 Cytochrome C oxidase, mono-heme subunit/FixO - - - 0.000000000000000000000000003755 125.0
CH2_k127_9187671_5 PFAM Rieske 2Fe-2S domain - - - 0.000000000001189 79.0
CH2_k127_9187671_6 Cytochrome c - - - 0.0000001061 64.0
CH2_k127_9256641_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 1.937e-223 696.0
CH2_k127_9256641_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 575.0
CH2_k127_9256641_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 460.0
CH2_k127_9256641_3 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000897 251.0
CH2_k127_9256641_4 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000008731 256.0
CH2_k127_9256641_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000002021 247.0
CH2_k127_9256641_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000004629 239.0
CH2_k127_9256641_7 His Kinase A (phosphoacceptor) domain K07642 - 2.7.13.3 0.000000001284 70.0
CH2_k127_9256641_8 Transmembrane anti-sigma factor - - - 0.0000001707 62.0
CH2_k127_9256641_9 cellulase activity K01884 - 6.1.1.16 0.0007738 51.0
CH2_k127_9261107_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 414.0
CH2_k127_9306991_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0 1035.0
CH2_k127_9306991_1 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000000002204 183.0
CH2_k127_9306991_2 bacterial-type flagellum organization K02282,K04562 - - 0.00000000000000001093 85.0
CH2_k127_9342030_0 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 5.151e-221 690.0
CH2_k127_9342030_1 long-chain fatty acid transporting porin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002003 286.0
CH2_k127_9342030_2 protein kinase activity - - - 0.0000000000003154 74.0
CH2_k127_9422714_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004919 407.0
CH2_k127_9423373_0 Uncharacterized protein family (UPF0051) K09014 - - 5.225e-275 850.0
CH2_k127_9423373_1 peptidyl-tyrosine sulfation - - - 4.586e-255 806.0
CH2_k127_9423373_2 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 2.724e-198 635.0
CH2_k127_9423373_3 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 486.0
CH2_k127_9423373_4 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 481.0
CH2_k127_9423373_5 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 394.0
CH2_k127_9423373_7 iron-sulfur cluster assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003174 258.0
CH2_k127_9423373_8 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000005315 233.0
CH2_k127_9424032_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 7.246e-253 791.0
CH2_k127_9424032_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 293.0
CH2_k127_9424032_2 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000000000000000000000000000005012 181.0
CH2_k127_9424032_3 - - - - 0.00000000000003332 78.0
CH2_k127_9424032_4 thiolester hydrolase activity K01055,K02170 - 3.1.1.24,3.1.1.85 0.00000000000007643 86.0
CH2_k127_9434537_0 PFAM Transposase, IS4-like - - - 0.00000000000000000000000000000000000000000000000000000008177 218.0
CH2_k127_9434537_1 - - - - 0.00000003648 61.0
CH2_k127_947235_0 PFAM ABC transporter K15738 - - 1.136e-304 946.0
CH2_k127_947235_1 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000001457 111.0
CH2_k127_947235_2 - - - - 0.00000001245 63.0
CH2_k127_9478553_0 PFAM glycosyl transferase family 9 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 490.0
CH2_k127_9488742_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 512.0
CH2_k127_9488742_1 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 399.0
CH2_k127_9488742_2 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 292.0
CH2_k127_9488742_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000313 183.0
CH2_k127_9506425_0 DinB family - - - 0.0000000000000000000000000000000000000000000000002858 189.0
CH2_k127_9506425_1 DNA-binding transcription factor activity - - - 0.0000000000000000000000005039 108.0
CH2_k127_9517813_0 stress-induced mitochondrial fusion - - - 0.0 1034.0
CH2_k127_9517813_1 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 537.0
CH2_k127_9517813_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 421.0
CH2_k127_9517813_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005839 287.0
CH2_k127_9517813_4 hydrolase of the alpha beta superfamily K07017 - - 0.00000000000000000000000000000000000000000000000000000000000000000004638 248.0
CH2_k127_9517813_5 - - - - 0.00000000000141 72.0
CH2_k127_952837_0 dTDP biosynthetic process K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 329.0
CH2_k127_952837_1 phosphatase activity K07025,K20862 - 3.1.3.102,3.1.3.104 0.0000000000000000000000000000000000000000000000000000000000000000003101 243.0
CH2_k127_952837_2 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000003543 224.0
CH2_k127_952837_3 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000009928 235.0
CH2_k127_952837_5 - - - - 0.0003338 52.0
CH2_k127_953265_0 Participates in both transcription termination and antitermination K02600 - - 4.339e-217 680.0
CH2_k127_953265_1 geranylgeranyl reductase activity K16431,K21256 - - 1.919e-204 653.0
CH2_k127_953265_2 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 550.0
CH2_k127_953265_3 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 506.0
CH2_k127_953265_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 467.0
CH2_k127_953265_5 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001351 248.0
CH2_k127_953265_6 Thioredoxin-like - - - 0.000000000000000000000000000000002125 140.0
CH2_k127_953265_7 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000002315 127.0
CH2_k127_9550936_0 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 605.0
CH2_k127_9550936_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 557.0
CH2_k127_9550936_10 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000002697 153.0
CH2_k127_9550936_11 Zn-dependent protease contains TPR repeats - - - 0.00000000000000000000000000000000000134 147.0
CH2_k127_9550936_12 - - - - 0.00000303 57.0
CH2_k127_9550936_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 488.0
CH2_k127_9550936_3 Belongs to the uridine kinase family K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 332.0
CH2_k127_9550936_4 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005278 271.0
CH2_k127_9550936_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000232 267.0
CH2_k127_9550936_6 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004062 252.0
CH2_k127_9550936_8 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000002099 225.0
CH2_k127_9588807_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.082e-195 620.0
CH2_k127_9588807_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 373.0
CH2_k127_9588807_3 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000001054 86.0
CH2_k127_9591465_0 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 532.0
CH2_k127_9591465_1 PFAM YCII-related - - - 0.000000000000000000000000000000000001953 153.0
CH2_k127_9591465_2 - - - - 0.000000000000000000000000803 108.0
CH2_k127_9601265_0 RmuC domain protein K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 304.0
CH2_k127_9601265_1 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005759 275.0
CH2_k127_9601265_2 Aminotransferase class IV K03342 - 2.6.1.85,4.1.3.38 0.0000000007151 59.0
CH2_k127_9601265_3 Domain of unknown function (DUF4440) - - - 0.000005344 55.0
CH2_k127_9650721_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1138.0
CH2_k127_9650721_1 Hydrolase CocE NonD family - - - 1.92e-296 930.0
CH2_k127_9650721_2 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 603.0
CH2_k127_9650721_3 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 416.0
CH2_k127_9650721_4 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000001707 257.0
CH2_k127_9662905_0 SWIM zinc finger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 477.0
CH2_k127_9662905_1 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000001844 184.0
CH2_k127_9669851_0 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 356.0
CH2_k127_9669851_1 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000000000000000000000000001183 183.0
CH2_k127_9669851_2 diguanylate cyclase - - - 0.00000000000004092 80.0
CH2_k127_9669851_3 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0002151 48.0
CH2_k127_9673101_0 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 584.0
CH2_k127_9673101_1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K00973,K00992 GO:0000166,GO:0000270,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006040,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019752,GO:0030203,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044281,GO:0046872,GO:0070569,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.7.13,2.7.7.24,2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000005969 216.0
CH2_k127_9673101_2 m protein repeat protein K20293 - - 0.0000334 56.0
CH2_k127_9698589_0 Sigma-70 region 3 K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 469.0
CH2_k127_9698589_1 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000000000000000000000000000000004516 187.0
CH2_k127_9698589_2 actin binding - - - 0.000000000000000000000000000000000000000000002354 181.0
CH2_k127_9712656_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1982.0
CH2_k127_9712656_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 397.0
CH2_k127_9718342_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1287.0
CH2_k127_9718342_1 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000005058 250.0
CH2_k127_9720725_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 2.193e-244 765.0
CH2_k127_9720725_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 319.0
CH2_k127_9724235_0 Prolyl oligopeptidase - - - 5.288e-217 684.0
CH2_k127_9734765_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1043.0
CH2_k127_9734765_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 401.0
CH2_k127_9734765_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 359.0
CH2_k127_9734765_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001558 256.0
CH2_k127_9734765_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006794 242.0
CH2_k127_9734765_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000000003019 198.0
CH2_k127_9837880_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 304.0
CH2_k127_9837880_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000004739 198.0
CH2_k127_9840890_0 PFAM Na dependent nucleoside transporter K03317 - - 8.788e-230 718.0
CH2_k127_9840890_3 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 479.0
CH2_k127_9840890_5 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009396 314.0
CH2_k127_9840890_7 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000004053 119.0
CH2_k127_9868492_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 349.0
CH2_k127_9868492_1 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 345.0
CH2_k127_9868492_2 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001306 281.0
CH2_k127_9877593_0 Amino acid permease - - - 2.314e-256 804.0
CH2_k127_9899381_0 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 534.0
CH2_k127_9899381_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 317.0
CH2_k127_9899381_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000001731 139.0
CH2_k127_993175_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 1.545e-222 696.0
CH2_k127_993175_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 5.388e-204 645.0
CH2_k127_993175_2 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 521.0
CH2_k127_993175_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006476 515.0
CH2_k127_993175_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 381.0
CH2_k127_993175_5 antisigma factor binding K04749 - - 0.00000000000000000000000000000000000000000000000000000009881 206.0
CH2_k127_993175_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000000005858 151.0
CH2_k127_9945271_0 transferase activity, transferring hexosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 516.0
CH2_k127_9945271_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 437.0
CH2_k127_9945271_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 412.0
CH2_k127_9945271_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 344.0
CH2_k127_9945271_4 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006471 259.0
CH2_k127_9945271_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003297 237.0
CH2_k127_9945271_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000009847 220.0
CH2_k127_9945271_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000008566 221.0
CH2_k127_9984326_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 374.0
CH2_k127_9984326_1 ABC transporter K02013 - 3.6.3.34 0.00000000000000004404 83.0
CH2_k127_9997148_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 506.0
CH2_k127_9997148_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000007498 213.0
CH2_k127_9997148_2 AMP binding - - - 0.000000000000000000000000000000000002389 146.0
CH2_k127_9997148_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000008448 68.0