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Overview

ID MAG00243
Name CH2_bin.28
Sample SMP0008
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Methylococcales
Family Methylomonadaceae
Genus
Species
Assembly information
Completeness (%) 84.71
Contamination (%) 2.14
GC content (%) 53.0
N50 (bp) 6,746
Genome size (bp) 2,284,608

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2357

Gene name Description KEGG GOs EC E-value Score Sequence
CH2_k127_10038060_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 469.0
CH2_k127_10038060_1 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000006403 239.0
CH2_k127_10038060_2 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000001118 171.0
CH2_k127_10045493_0 ZIP Zinc transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 472.0
CH2_k127_10045493_1 TIGRFAM TIGR00266 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 302.0
CH2_k127_10045493_2 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004085 267.0
CH2_k127_10045493_3 Phosphopantetheine attachment site - - - 0.0000000000000000000000000006725 114.0
CH2_k127_10045493_4 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.000000000000002731 83.0
CH2_k127_10071860_0 Transport of potassium into the cell K03549 - - 0.0 1002.0
CH2_k127_10071860_1 PFAM Type IV pilus assembly PilZ - - - 0.0000000000008622 74.0
CH2_k127_10071860_2 Histidine kinase K07646 - 2.7.13.3 0.0000000005733 59.0
CH2_k127_10073862_0 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 8.324e-211 663.0
CH2_k127_10073862_1 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 9.262e-200 631.0
CH2_k127_10073862_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033036,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 292.0
CH2_k127_10073862_3 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000374 263.0
CH2_k127_10073862_4 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000001603 228.0
CH2_k127_10073862_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000002785 223.0
CH2_k127_10073862_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000000000000000000000000000007949 193.0
CH2_k127_10073862_7 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000000000000000003401 113.0
CH2_k127_10192504_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 8.006e-266 834.0
CH2_k127_10192504_1 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 333.0
CH2_k127_10192504_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005169 263.0
CH2_k127_10192504_3 zinc ion binding K06204 - - 0.00000000000000000000000000000001628 126.0
CH2_k127_10244506_0 Ammonium Transporter K03320 - - 1.046e-245 768.0
CH2_k127_10244506_1 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04752 - - 0.0000000000000000000000000000000000000000000000000000001136 196.0
CH2_k127_10244506_2 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000259 183.0
CH2_k127_10254694_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.685e-220 691.0
CH2_k127_10254694_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 604.0
CH2_k127_10254694_2 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 346.0
CH2_k127_10254694_3 - - - - 0.0000000000000000000000000000000000000000000003167 176.0
CH2_k127_10254694_4 2 iron, 2 sulfur cluster binding - - - 0.000000000000000000000000001031 118.0
CH2_k127_10254694_5 Alginate export - - - 0.00000000000000000000000001027 111.0
CH2_k127_10254694_6 - - - - 0.00001145 50.0
CH2_k127_10254694_7 Alginate export - - - 0.00001774 47.0
CH2_k127_10254694_8 Extracellular solute-binding protein K02048 - - 0.00002578 47.0
CH2_k127_10256072_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 516.0
CH2_k127_10256072_1 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003486 292.0
CH2_k127_10256072_2 Membrane K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001772 255.0
CH2_k127_10316102_0 Belongs to the RimK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 426.0
CH2_k127_10316102_1 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 348.0
CH2_k127_10316102_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 320.0
CH2_k127_10316102_3 PFAM Formaldehyde-activating enzyme K10713 - 4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 298.0
CH2_k127_10316102_4 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000001154 226.0
CH2_k127_10316102_5 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016787,GO:0016810,GO:0016814,GO:0018759,GO:0019238,GO:0043446,GO:0044237,GO:0071704 3.5.4.27 0.000000000000000000000000000000001687 129.0
CH2_k127_10372436_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 0.0 1260.0
CH2_k127_1038028_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1420.0
CH2_k127_1038028_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1405.0
CH2_k127_1038028_2 DNA photolyase K01669 - 4.1.99.3 1.193e-214 676.0
CH2_k127_1038028_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 432.0
CH2_k127_1038028_4 transcriptional regulator, Crp K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 319.0
CH2_k127_1038028_5 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000007313 229.0
CH2_k127_10387261_0 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 346.0
CH2_k127_10387261_1 PFAM Rhodanese-like K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 295.0
CH2_k127_10387261_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.000000000000000000000000000000000007866 138.0
CH2_k127_10387261_3 Major Facilitator Superfamily - - - 0.0000001271 55.0
CH2_k127_10387261_4 Belongs to the SOS response-associated peptidase family - - - 0.000001216 50.0
CH2_k127_10387261_5 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) K01214 - 3.2.1.68 0.000002465 49.0
CH2_k127_10444616_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 410.0
CH2_k127_10444616_1 UDP-N-acetylglucosamine 2-epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 359.0
CH2_k127_10444616_2 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 296.0
CH2_k127_10444616_3 - - - - 0.0000000000000000000000005772 109.0
CH2_k127_10454996_0 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 373.0
CH2_k127_10454996_1 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 367.0
CH2_k127_10454996_2 Sigma-54 interaction domain K07715 - - 0.000000000000000000000000000000000000000000000000000000000183 209.0
CH2_k127_10454996_3 PFAM NADH ubiquinone K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000002207 164.0
CH2_k127_10457500_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.431e-245 761.0
CH2_k127_10457500_1 PilZ domain - - - 0.00000000000000000000000000000000000000000000000001001 188.0
CH2_k127_10457500_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000002622 165.0
CH2_k127_10457500_3 Cytochrome c - - - 0.0000000000000000000000000000001162 128.0
CH2_k127_10457500_4 Protein of unknown function (DUF2905) - - - 0.000000000000000000000000179 106.0
CH2_k127_10462350_0 GTP-binding protein, HSR1-related - - - 7.604e-291 894.0
CH2_k127_10462350_1 Protein of unknown function (DUF2868) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 381.0
CH2_k127_10462350_2 - - - - 0.00000000000000001991 81.0
CH2_k127_105126_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 611.0
CH2_k127_105126_1 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 589.0
CH2_k127_105126_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 440.0
CH2_k127_105126_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003831 253.0
CH2_k127_105126_4 ATP synthase, subunit K02124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008597 243.0
CH2_k127_105126_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001102 231.0
CH2_k127_105126_6 subunit D K02120 - - 0.0000000000000000000000000000000000000000000000000003374 191.0
CH2_k127_10513819_0 sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 475.0
CH2_k127_10513819_1 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 349.0
CH2_k127_10513819_2 CHAD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001755 263.0
CH2_k127_10545328_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0 1195.0
CH2_k127_10545328_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 476.0
CH2_k127_10545328_2 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.000000000000000000000000000003703 119.0
CH2_k127_10545328_3 Phosphate acyltransferases - - - 0.00000000000000000000000004553 109.0
CH2_k127_10545328_6 Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation K11373 GO:0000003,GO:0000049,GO:0000123,GO:0000166,GO:0001932,GO:0002097,GO:0002098,GO:0002119,GO:0002164,GO:0002376,GO:0003006,GO:0003008,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004672,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006464,GO:0006468,GO:0006518,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006955,GO:0007154,GO:0007165,GO:0007249,GO:0007252,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007292,GO:0007549,GO:0007610,GO:0007611,GO:0007612,GO:0007635,GO:0008023,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008306,GO:0008355,GO:0008607,GO:0009047,GO:0009058,GO:0009059,GO:0009451,GO:0009653,GO:0009790,GO:0009791,GO:0009889,GO:0009987,GO:0009994,GO:0010467,GO:0010468,GO:0010556,GO:0016043,GO:0016070,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019207,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019887,GO:0019953,GO:0022412,GO:0022414,GO:0022607,GO:0023052,GO:0030154,GO:0030234,GO:0030334,GO:0030335,GO:0030554,GO:0031248,GO:0031323,GO:0031326,GO:0031399,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032504,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032879,GO:0032991,GO:0033588,GO:0034470,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0036477,GO:0040012,GO:0040017,GO:0040025,GO:0040029,GO:0042048,GO:0042221,GO:0042325,GO:0042995,GO:0043005,GO:0043025,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043549,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044297,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0044703,GO:0045859,GO:0046483,GO:0048232,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048569,GO:0048598,GO:0048599,GO:0048609,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0051171,GO:0051174,GO:0051246,GO:0051252,GO:0051270,GO:0051272,GO:0051338,GO:0051704,GO:0051716,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0097458,GO:0097659,GO:0098772,GO:0120025,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902493,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2000145,GO:2000147,GO:2001141 - 0.0007442 43.0
CH2_k127_1060648_0 Phage portal protein, lambda family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 372.0
CH2_k127_1060648_1 Phage capsid family - - - 0.000000000000000000000000000000000000000000000000000000000000000005028 233.0
CH2_k127_1060648_2 - - - - 0.000000000000000000000000002437 116.0
CH2_k127_10629692_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0 1469.0
CH2_k127_10629692_1 Phage late control gene D protein (GPD) K11904 - - 0.0 1136.0
CH2_k127_10629692_2 Type VI secretion, TssG K11895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 548.0
CH2_k127_10629692_3 type VI secretion protein K11896 - - 0.000000000000000000000009157 109.0
CH2_k127_10634494_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 1.954e-242 755.0
CH2_k127_10634494_1 - - - - 0.00000005767 57.0
CH2_k127_10664753_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1298.0
CH2_k127_10664753_1 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 3.45e-200 632.0
CH2_k127_10664753_2 3-beta hydroxysteroid dehydrogenase/isomerase family K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 569.0
CH2_k127_10664753_3 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 473.0
CH2_k127_10664753_4 ABC transporter permease protein K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 323.0
CH2_k127_10664753_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 289.0
CH2_k127_10664753_6 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 286.0
CH2_k127_10664753_7 molybdenum ABC transporter, periplasmic K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000004989 224.0
CH2_k127_10664753_8 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000101 182.0
CH2_k127_10664753_9 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000000000000000002366 159.0
CH2_k127_10677800_0 ABC transporter C-terminal domain K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 462.0
CH2_k127_10677800_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 318.0
CH2_k127_10712668_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 597.0
CH2_k127_10712668_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 565.0
CH2_k127_10712668_2 6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 300.0
CH2_k127_10736977_0 PFAM Binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 367.0
CH2_k127_10736977_1 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 332.0
CH2_k127_10736977_2 pfam ammecr1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003822 267.0
CH2_k127_10736977_3 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000004927 212.0
CH2_k127_10736977_4 - - - - 0.000000000000006922 82.0
CH2_k127_10736977_5 - - - - 0.000000000004664 72.0
CH2_k127_10758192_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.078e-295 912.0
CH2_k127_10758192_1 TIGRFAM Coenzyme PQQ biosynthesis protein E K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 4.171e-210 656.0
CH2_k127_10758192_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000008045 164.0
CH2_k127_10758192_11 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000282 147.0
CH2_k127_10758192_12 TIGRFAM coenzyme PQQ biosynthesis protein PqqD K06138 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000000000000000000000005499 136.0
CH2_k127_10758192_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000002934 127.0
CH2_k127_10758192_14 Putative restriction endonuclease - - - 0.00000000000000000000000008798 109.0
CH2_k127_10758192_15 - - - - 0.00000000000001304 79.0
CH2_k127_10758192_16 endonuclease III K01247 - 3.2.2.21 0.000000000002038 68.0
CH2_k127_10758192_17 - - - - 0.00000001974 58.0
CH2_k127_10758192_2 May be involved in the transport of PQQ or its precursor to the periplasm K06136 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003097 526.0
CH2_k127_10758192_3 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 462.0
CH2_k127_10758192_4 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007883 437.0
CH2_k127_10758192_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 389.0
CH2_k127_10758192_6 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 372.0
CH2_k127_10758192_7 transcriptional regulator K13634 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 350.0
CH2_k127_10758192_8 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000000000000000000000004387 217.0
CH2_k127_10758192_9 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000004335 184.0
CH2_k127_10761394_0 2-oxoglutarate dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1386.0
CH2_k127_10761394_1 ABC transporter transmembrane region K06148 - - 7.897e-279 868.0
CH2_k127_10761394_10 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 300.0
CH2_k127_10761394_11 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005296 276.0
CH2_k127_10761394_12 Domain in histone-like proteins of HNS family K03746 - - 0.0000000000000000000000000000003611 126.0
CH2_k127_10761394_14 - - - - 0.000002702 50.0
CH2_k127_10761394_2 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 1.965e-225 702.0
CH2_k127_10761394_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 2.361e-217 677.0
CH2_k127_10761394_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 577.0
CH2_k127_10761394_5 Soluble lytic murein transglycosylase L domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 584.0
CH2_k127_10761394_6 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 543.0
CH2_k127_10761394_7 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 482.0
CH2_k127_10761394_8 PHP domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 367.0
CH2_k127_10761394_9 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 317.0
CH2_k127_10793670_0 PFAM Transposase, IS4-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 479.0
CH2_k127_10793670_1 Transposase IS4 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 376.0
CH2_k127_10793670_2 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 323.0
CH2_k127_10798281_0 Orotidine 5'-phosphate decarboxylase / HUMPS family K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 608.0
CH2_k127_10798281_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 485.0
CH2_k127_10798281_2 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 407.0
CH2_k127_10798281_3 Putative inner membrane protein (DUF1819) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 244.0
CH2_k127_10798281_4 NlpB/DapX lipoprotein K07287 - - 0.000000000000000000000000000000000001414 152.0
CH2_k127_10798281_5 Domain of unknown function (DUF1788) - - - 0.0000000000000000000000000000002158 126.0
CH2_k127_10807977_0 PFAM ATP-grasp fold - - - 2.198e-245 764.0
CH2_k127_10807977_1 Protein of unknown function (DUF2817) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007982 482.0
CH2_k127_10807977_2 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000000000000002505 201.0
CH2_k127_10830500_0 50S ribosome-binding GTPase - - - 5.164e-198 632.0
CH2_k127_10830500_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 390.0
CH2_k127_10830500_2 50S ribosome-binding GTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 388.0
CH2_k127_10830500_3 - - - - 0.00000000000000000000000000000000000000000000000000000000007912 211.0
CH2_k127_10830500_4 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000004812 191.0
CH2_k127_10865634_0 2 iron, 2 sulfur cluster binding - - - 0.0 1494.0
CH2_k127_10889042_0 FeS assembly protein SufB K09014 - - 8.882e-275 849.0
CH2_k127_10889042_1 PFAM Polyphosphate kinase 2 - - - 1.062e-215 679.0
CH2_k127_10889042_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 364.0
CH2_k127_10889042_3 C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 362.0
CH2_k127_10889042_4 ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 310.0
CH2_k127_10889042_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005186 259.0
CH2_k127_10889042_6 TIGRFAM SUF system FeS cluster assembly, Rtf2-type regulator - - - 0.0000000000000000000000000000000000000000000000000000000001215 206.0
CH2_k127_10889042_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000001905 155.0
CH2_k127_10889042_8 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000001175 139.0
CH2_k127_10889042_9 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000004056 131.0
CH2_k127_10905952_0 PFAM sulfatase K01130 - 3.1.6.1 0.0 1080.0
CH2_k127_10905952_1 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000621 149.0
CH2_k127_10905952_2 Glycine-zipper domain - - - 0.00000000000000000000000004401 112.0
CH2_k127_10949151_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 449.0
CH2_k127_10949151_1 TonB dependent receptor K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 328.0
CH2_k127_10949151_2 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008899 257.0
CH2_k127_10949151_3 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.00000000000000000000000000000000000002814 144.0
CH2_k127_10949151_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000000002596 133.0
CH2_k127_10949151_5 COGs COG1487 nucleic acid-binding protein contains PIN domain K18828 - - 0.0000000000000000000000000000465 121.0
CH2_k127_10949151_6 - - - - 0.000000000000159 74.0
CH2_k127_10976423_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 7.947e-249 772.0
CH2_k127_10976423_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 436.0
CH2_k127_10976423_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000003745 259.0
CH2_k127_11016622_0 recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 553.0
CH2_k127_11016622_1 Pfam SEC-C motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 436.0
CH2_k127_11016622_10 - - - - 0.000000000000002342 79.0
CH2_k127_11016622_11 integrase family K07357,K07358 - - 0.000000000000006082 74.0
CH2_k127_11016622_12 Transcriptional regulator - - - 0.000000000003565 74.0
CH2_k127_11016622_13 Protein of unknown function (DUF1778) - - - 0.0000000001101 64.0
CH2_k127_11016622_14 - - - - 0.00000006132 53.0
CH2_k127_11016622_15 Phage derived protein Gp49-like (DUF891) - - - 0.0000007238 51.0
CH2_k127_11016622_16 Belongs to the RelE toxin family K19092 - - 0.000005802 53.0
CH2_k127_11016622_17 nucleotidyltransferase activity - - - 0.0005763 44.0
CH2_k127_11016622_2 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000001172 187.0
CH2_k127_11016622_3 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000000000000000000000000000008635 184.0
CH2_k127_11016622_4 - - - - 0.0000000000000000000000000000000003242 136.0
CH2_k127_11016622_5 - K07039 - - 0.00000000000000000000000000000004053 128.0
CH2_k127_11016622_6 Proposed nucleic acid binding domain - - - 0.000000000000000000000000000002245 121.0
CH2_k127_11016622_7 Protein of unknown function (DUF1778) - - - 0.0000000000000000000003934 99.0
CH2_k127_11016622_8 addiction module antidote protein, CC2985 K07746 - - 0.00000000000000001965 85.0
CH2_k127_11016622_9 Domain of unknown function (DUF4160) - - - 0.00000000000000003362 84.0
CH2_k127_1103809_0 modulator of DNA gyrase K03568 - - 1.703e-213 668.0
CH2_k127_1103809_1 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 499.0
CH2_k127_1103809_2 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000003547 226.0
CH2_k127_11050419_0 Phage capsid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 586.0
CH2_k127_11050419_1 Phage portal protein, lambda family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 365.0
CH2_k127_11050419_2 - - - - 0.0000000000000000000000000000000000002574 147.0
CH2_k127_1107623_0 Belongs to the UPF0753 family K09822 - - 0.0 1225.0
CH2_k127_1107623_1 PFAM Sulfate transporter family - - - 1.53e-230 726.0
CH2_k127_1107623_10 Glycosyl transferase family 8 - - - 0.00000000000000000000000000000000006673 136.0
CH2_k127_1107623_11 GMC oxidoreductase - - - 0.00000000000000000000000000001374 128.0
CH2_k127_1107623_12 PFAM Transposase, IS4-like - - - 0.0000000000000000000002196 99.0
CH2_k127_1107623_13 Glycosyl transferase, family 2 - - - 0.000000000002313 67.0
CH2_k127_1107623_14 - - - - 0.000000000004038 72.0
CH2_k127_1107623_15 Glycosyl transferase family 8 - - - 0.00000000002488 66.0
CH2_k127_1107623_2 Proton-conducting membrane transporter K00342 - 1.6.5.3 9.53e-202 640.0
CH2_k127_1107623_3 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 614.0
CH2_k127_1107623_4 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 598.0
CH2_k127_1107623_5 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 578.0
CH2_k127_1107623_6 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 527.0
CH2_k127_1107623_7 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 332.0
CH2_k127_1107623_8 response regulator - - - 0.00000000000000000000000000000000004559 136.0
CH2_k127_1107623_9 Glycosyltransferase, group 1 family protein - - - 0.00000000000000000000000000000000004953 140.0
CH2_k127_11155521_0 Proton-conducting membrane transporter - - - 4.521e-221 697.0
CH2_k127_11155521_1 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 441.0
CH2_k127_11155521_2 Proton-conducting membrane transporter K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 358.0
CH2_k127_11155521_3 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003141 244.0
CH2_k127_1117854_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1029.0
CH2_k127_1117854_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 539.0
CH2_k127_1117854_2 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 490.0
CH2_k127_1117854_3 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000004814 85.0
CH2_k127_1117854_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000002508 77.0
CH2_k127_11222819_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.133e-313 969.0
CH2_k127_11222819_1 chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 441.0
CH2_k127_11222819_3 Belongs to the carbohydrate kinase PfkB family. LacC subfamily K00882 - 2.7.1.56 0.000000000000000009795 89.0
CH2_k127_11239678_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 528.0
CH2_k127_11239678_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 387.0
CH2_k127_11239678_2 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003278 280.0
CH2_k127_11239678_3 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000001261 214.0
CH2_k127_11239678_4 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.00000001082 59.0
CH2_k127_11239678_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0001674 47.0
CH2_k127_11246350_0 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 512.0
CH2_k127_11246350_1 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.000000291 52.0
CH2_k127_1124854_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1356.0
CH2_k127_1124854_1 Polysaccharide biosynthesis protein - - - 8.67e-243 757.0
CH2_k127_1124854_10 - - - - 0.0000004408 51.0
CH2_k127_1124854_11 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0008703 43.0
CH2_k127_1124854_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.444e-215 674.0
CH2_k127_1124854_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 589.0
CH2_k127_1124854_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 538.0
CH2_k127_1124854_5 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000002271 143.0
CH2_k127_1124854_6 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.000000000000000000000000000008132 120.0
CH2_k127_1124854_7 Displays ATPase and GTPase activities K06958 - - 0.0000000000000001843 79.0
CH2_k127_1124854_9 Belongs to the 'phage' integrase family - - - 0.00000000000002057 73.0
CH2_k127_11260052_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.319e-255 801.0
CH2_k127_11260052_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 8.853e-203 634.0
CH2_k127_11260052_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 398.0
CH2_k127_11260052_3 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000000000000000001203 163.0
CH2_k127_11260052_4 Bacterial protein of unknown function (DUF853) K06915 - - 0.000000001941 58.0
CH2_k127_11260356_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.843e-232 734.0
CH2_k127_11260356_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 581.0
CH2_k127_11260356_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 551.0
CH2_k127_11260356_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 514.0
CH2_k127_11260356_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 381.0
CH2_k127_11260356_5 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000122 244.0
CH2_k127_11260356_6 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000001574 123.0
CH2_k127_11260356_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000004682 61.0
CH2_k127_11260356_8 - - - - 0.000000005667 58.0
CH2_k127_11279225_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0 1011.0
CH2_k127_11279225_1 PFAM Major Facilitator Superfamily K08227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 526.0
CH2_k127_11279225_2 Sensors of blue-light using FAD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 298.0
CH2_k127_11279225_3 PFAM Transcriptional regulator, TetR-like, DNA-binding, bacterial archaeal - - - 0.00000000000000000000000000000000000000000000000001426 187.0
CH2_k127_11279225_4 Cytochrome bd-type quinol oxidase subunit 1 K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000001247 167.0
CH2_k127_11279225_5 - - - - 0.00000000000000002536 90.0
CH2_k127_11281560_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 9.261e-214 666.0
CH2_k127_11281560_1 TIGRFAM Mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 611.0
CH2_k127_11281560_10 - - - - 0.0000000000000007758 83.0
CH2_k127_11281560_2 PFAM Alpha-D-phosphohexomutase, alpha beta alpha domain I K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 553.0
CH2_k127_11281560_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 534.0
CH2_k127_11281560_4 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 469.0
CH2_k127_11281560_5 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 402.0
CH2_k127_11281560_6 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 392.0
CH2_k127_11281560_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000009098 256.0
CH2_k127_11281560_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001448 244.0
CH2_k127_11281560_9 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000000000000000000004855 207.0
CH2_k127_11282030_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 602.0
CH2_k127_11282030_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 578.0
CH2_k127_11282030_11 PilZ domain - - - 0.0000000000000003587 82.0
CH2_k127_11282030_12 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0005488,GO:0030973,GO:0043167,GO:0043168 - 0.00000008257 58.0
CH2_k127_11282030_2 glycyl-tRNA synthetase K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005002 469.0
CH2_k127_11282030_3 PFAM Staphylococcal nuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003726 255.0
CH2_k127_11282030_4 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000005118 218.0
CH2_k127_11282030_5 UPF0056 inner membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000001488 221.0
CH2_k127_11282030_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000000005394 205.0
CH2_k127_11282030_7 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.00000000000000000000000000000000000000000000000005987 181.0
CH2_k127_11282030_8 Protein of unknown function (DUF1249) K09920 - - 0.0000000000000000000000000000000000000000001578 163.0
CH2_k127_11282030_9 membrane - - - 0.000000000000000000000000000000003941 132.0
CH2_k127_11284833_0 Citrate transporter - - - 1.18e-222 697.0
CH2_k127_11284833_1 PFAM Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 516.0
CH2_k127_11284833_2 reductase 4Fe-4S K00381 - 1.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 476.0
CH2_k127_11284833_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 441.0
CH2_k127_11284833_4 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 327.0
CH2_k127_11289053_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 439.0
CH2_k127_11289053_1 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009672 302.0
CH2_k127_11289053_2 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000005024 241.0
CH2_k127_11289053_3 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000002594 179.0
CH2_k127_11289053_4 - - - - 0.000000000000000000000000000000008845 137.0
CH2_k127_11289053_5 Phage shock protein A K03615,K03969,K09749,K21471 - - 0.00000000000000000000003522 106.0
CH2_k127_11289053_6 - - - - 0.000000002961 66.0
CH2_k127_11289053_7 - - - - 0.000000005492 60.0
CH2_k127_11289948_0 Belongs to the transketolase family - - - 0.0 1119.0
CH2_k127_11289948_1 PFAM Multicopper oxidase - - - 3.657e-223 709.0
CH2_k127_11289948_10 - - - - 0.000000000000000000000059 105.0
CH2_k127_11289948_11 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000006256 87.0
CH2_k127_11289948_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 581.0
CH2_k127_11289948_3 Lycopene cyclase protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 512.0
CH2_k127_11289948_4 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 467.0
CH2_k127_11289948_5 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 439.0
CH2_k127_11289948_6 membrane - - - 0.000000000000000000000000000000000000000000000000001781 191.0
CH2_k127_11289948_7 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.00000000000000000000000000000000000000008509 160.0
CH2_k127_11289948_8 - - - - 0.000000000000000000000000000000001283 138.0
CH2_k127_11289948_9 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000000001112 122.0
CH2_k127_11291946_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 4.25e-212 667.0
CH2_k127_11291946_1 DnaJ C terminal domain K05516 - - 0.0000000000000000000000000000000000000000000000000222 180.0
CH2_k127_11335494_0 Helix-hairpin-helix containing domain - - - 0.0 1019.0
CH2_k127_11335494_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009109 551.0
CH2_k127_11350294_0 MacB-like periplasmic core domain K02004 - - 0.0 1026.0
CH2_k127_11350294_1 SMART Signal transduction response regulator, receiver region - - - 6.625e-238 742.0
CH2_k127_11350294_2 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 569.0
CH2_k127_11350294_3 PFAM Sulphate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000003288 239.0
CH2_k127_11350294_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000004428 204.0
CH2_k127_11386060_0 PFAM Xylulose 5-phosphate Fructose 6-phosphate phosphoketolase, N-terminal K01621 GO:0003674,GO:0003824,GO:0008150,GO:0009758 4.1.2.22,4.1.2.9 0.0 1379.0
CH2_k127_11386060_1 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 305.0
CH2_k127_11386060_2 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000005753 163.0
CH2_k127_11386060_3 glycerophosphoryl diester phosphodiesterase K01126 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0008081,GO:0008889,GO:0016787,GO:0016788,GO:0042578,GO:0043167,GO:0043169,GO:0046872,GO:0047389,GO:0047395 3.1.4.46 0.00000000000000002244 85.0
CH2_k127_11411397_0 Adenylate and Guanylate cyclase catalytic domain - - - 2.163e-286 919.0
CH2_k127_11411397_1 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 571.0
CH2_k127_11411397_2 Protein of unknown function (DUF3422) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 435.0
CH2_k127_11411397_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 313.0
CH2_k127_11411397_4 Macrophage migration inhibitory factor - - - 0.00000000000000000000000000000000000000000000246 166.0
CH2_k127_11411397_5 Protein of unknown function (DUF2956) - - - 0.000000000000000000000000000000000000003532 148.0
CH2_k127_11411397_6 Biotin-lipoyl like K02005 - - 0.0000001811 53.0
CH2_k127_11435026_0 Isocitrate/isopropylmalate dehydrogenase K00031 GO:0000287,GO:0003674,GO:0003824,GO:0004448,GO:0004450,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006102,GO:0008150,GO:0008152,GO:0008270,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016614,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044464,GO:0045333,GO:0046487,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:0072350 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 595.0
CH2_k127_11435026_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 463.0
CH2_k127_11435026_2 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 318.0
CH2_k127_11435026_3 PFAM Multicopper oxidase, type K04753,K08100,K14588 - 1.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000005796 223.0
CH2_k127_11435026_5 Stress responsive A/B Barrel Domain - - - 0.0000000000000000000000000000000000000004907 153.0
CH2_k127_11435026_6 ABC transporter K02003 - - 0.0000000000000000000000000000000005535 132.0
CH2_k127_1146265_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1001.0
CH2_k127_1146265_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 6.204e-197 619.0
CH2_k127_1146265_2 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 484.0
CH2_k127_1146265_3 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006483 270.0
CH2_k127_1146265_4 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000000000000000000000000000000000459 225.0
CH2_k127_1146265_5 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000003394 107.0
CH2_k127_1146265_6 Protein of unknown function (DUF2909) - - - 0.000000000000000002819 88.0
CH2_k127_1146367_0 Sodium:neurotransmitter symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 327.0
CH2_k127_11463752_0 - - - - 2.549e-305 939.0
CH2_k127_11463752_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002864 283.0
CH2_k127_11463752_2 Ecotin K08276 - - 0.0000000000000000000000000000001552 129.0
CH2_k127_11463752_3 - - - - 0.000000000000000000000000000184 116.0
CH2_k127_11463752_4 mechanosensitive ion channel - - - 0.0000000000000000002972 89.0
CH2_k127_11463752_5 transmembrane transport K03442,K22044 - - 0.0005378 48.0
CH2_k127_11527410_0 tRNA (guanine-N7-)-methyltransferase activity - - - 0.0 1047.0
CH2_k127_11527410_1 PFAM Aminotransferase, class I K00812,K02028,K12252 - 2.6.1.1,2.6.1.84,3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 565.0
CH2_k127_11527410_2 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 299.0
CH2_k127_11527410_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000008797 247.0
CH2_k127_11527410_4 Domain of unknown function (DUF4160) - - - 0.00000000000000000000000000000000000000000004765 161.0
CH2_k127_11527410_5 Protein of unknown function (DUF2442) - - - 0.00000000000000000000000000000000000001621 146.0
CH2_k127_11527410_6 PFAM Peptidase S8 S53, subtilisin kexin sedolisin - - - 0.00000000000006882 76.0
CH2_k127_11527410_7 Nacht domain - - - 0.00000009685 55.0
CH2_k127_11714165_0 BT1 family - - - 1.88e-251 786.0
CH2_k127_11714165_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 7.097e-207 650.0
CH2_k127_11714165_2 Glycosyl hydrolases family 17 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 610.0
CH2_k127_11714165_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 594.0
CH2_k127_11714165_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 555.0
CH2_k127_11714165_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 315.0
CH2_k127_11714165_6 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000000000000000000000000000000000000002222 153.0
CH2_k127_11714165_7 HupE / UreJ protein K03192 - - 0.0000000000000000000000000000000000001126 148.0
CH2_k127_11715664_0 Bacterial regulatory protein, Fis family K02481,K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 535.0
CH2_k127_11715664_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 426.0
CH2_k127_11717891_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 6.75e-264 818.0
CH2_k127_11717891_1 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 513.0
CH2_k127_11717891_2 Membrane-bound serine protease (ClpP class) K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 492.0
CH2_k127_11717891_3 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 358.0
CH2_k127_11717891_4 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 305.0
CH2_k127_11717891_5 PFAM RNA recognition motif - - - 0.000000000000000000000000000000000000000003806 155.0
CH2_k127_11718109_0 Transport of potassium into the cell K03549 - - 3.147e-207 651.0
CH2_k127_11718109_1 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 5.282e-200 638.0
CH2_k127_11718109_2 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009743 344.0
CH2_k127_11718109_3 PFAM Uncharacterised protein family UPF0029, Impact, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000006614 229.0
CH2_k127_11718109_4 PFAM FAD linked oxidase domain protein K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 0.0000000000000000000000000000000000000002973 153.0
CH2_k127_11810056_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 6.557e-263 813.0
CH2_k127_11810056_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 395.0
CH2_k127_11810056_2 Toxic anion resistance family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 302.0
CH2_k127_11810056_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000002418 239.0
CH2_k127_11810056_4 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000002607 211.0
CH2_k127_11810056_5 - - - - 0.00000000000000000000000000000000000000000000000000000000001566 222.0
CH2_k127_11810056_6 membrane - - - 0.000000383 62.0
CH2_k127_11810056_7 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000008166 53.0
CH2_k127_11810056_8 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00006735 46.0
CH2_k127_11825185_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 424.0
CH2_k127_11825185_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0001416 44.0
CH2_k127_11839861_0 (Lipo)protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 323.0
CH2_k127_11839861_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000246 195.0
CH2_k127_11900105_0 Fatty acid cis/trans isomerase (CTI) - - - 6.448e-287 902.0
CH2_k127_11900105_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001258 280.0
CH2_k127_11900105_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000984 267.0
CH2_k127_11932005_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1091.0
CH2_k127_11932005_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.082e-233 727.0
CH2_k127_11932005_2 PFAM Aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 607.0
CH2_k127_11932005_3 Protein of unknown function (DUF2797) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 393.0
CH2_k127_11932005_4 - - - - 0.00000000000000000000000000009498 120.0
CH2_k127_11937289_0 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 486.0
CH2_k127_11937289_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 417.0
CH2_k127_11937289_2 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008993 347.0
CH2_k127_11966379_0 HI0933-like protein K10210 - 1.14.99.44 1.152e-267 829.0
CH2_k127_11966379_1 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 1.733e-258 802.0
CH2_k127_11966379_2 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 1.37e-230 724.0
CH2_k127_11966379_3 - - - - 0.000000000000000000000000000000000000002906 151.0
CH2_k127_11969322_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.856e-303 945.0
CH2_k127_11969322_1 COG2206 HD-GYP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 458.0
CH2_k127_11969322_2 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 423.0
CH2_k127_11969322_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 297.0
CH2_k127_11969322_4 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000001722 210.0
CH2_k127_11977287_0 Aldehyde dehydrogenase family - - - 8.428e-217 681.0
CH2_k127_11977287_1 Cobalamin-independent synthase, Catalytic domain - - - 0.00000000000000000000000000000000000000001166 154.0
CH2_k127_11977287_2 - - - - 0.00000000000000000000000585 106.0
CH2_k127_11977287_3 O-Antigen ligase - - - 0.0000007917 52.0
CH2_k127_11977287_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000003781 49.0
CH2_k127_1199229_0 SCO1/SenC - - - 1.128e-276 863.0
CH2_k127_1199229_1 56kDa selenium binding protein (SBP56) K17285 - - 5.299e-243 756.0
CH2_k127_1199229_2 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004259 277.0
CH2_k127_1199229_3 PFAM Transcriptional regulator, TetR-like, DNA-binding, bacterial archaeal K16137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003454 266.0
CH2_k127_1199229_4 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000000000001368 157.0
CH2_k127_1199229_5 TrkA-C domain K03499 - - 0.0000000000000000000000000000000000003631 141.0
CH2_k127_1199229_6 - - - - 0.0000000203 56.0
CH2_k127_12016200_0 PFAM Major Facilitator Superfamily K02575 - - 0.0 1496.0
CH2_k127_12016200_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007447 244.0
CH2_k127_12016200_2 Transcriptional regulator K13771 - - 0.0000000000000000000000000000000000000000000000000000001148 199.0
CH2_k127_12016200_3 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000005594 207.0
CH2_k127_12016200_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0000000000000000000000000000000001602 132.0
CH2_k127_12130221_0 Chromate transporter - - - 5.929e-236 735.0
CH2_k127_12130221_1 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001454 258.0
CH2_k127_12148202_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 1.906e-205 648.0
CH2_k127_12148202_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 2.308e-195 612.0
CH2_k127_12148202_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 427.0
CH2_k127_12148202_3 PFAM Mitochondrial inner membrane translocase complex, subunit Tim44-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 337.0
CH2_k127_12158164_0 PFAM Sulfatase - - - 0.0 1162.0
CH2_k127_12158164_1 Cytochrome c554 and c-prime - - - 1.336e-314 977.0
CH2_k127_12158164_2 esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 541.0
CH2_k127_12158164_3 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 355.0
CH2_k127_12158164_4 Domain of unknown function (DUF4410) - - - 0.0000000000000000000000000000000000000000000000000000000000000004701 226.0
CH2_k127_12158164_5 - - - - 0.00000000000000000000000000000000000000000000000009011 188.0
CH2_k127_12158164_6 - - - - 0.000000000000415 70.0
CH2_k127_12170480_0 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000009093 183.0
CH2_k127_12170480_1 N-terminal domain of unknown function (DUF4140) - - - 0.00000000000000000000000000000003453 139.0
CH2_k127_12186175_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 501.0
CH2_k127_12186175_1 AFG1-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 464.0
CH2_k127_12186175_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001605 271.0
CH2_k127_12186175_3 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000001339 209.0
CH2_k127_12186175_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000007734 137.0
CH2_k127_12186175_5 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000009809 74.0
CH2_k127_12225026_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1474.0
CH2_k127_12225026_1 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family - - - 0.0 1148.0
CH2_k127_12225026_10 - - - - 0.000001665 54.0
CH2_k127_12225026_11 - - - - 0.000002107 52.0
CH2_k127_12225026_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 402.0
CH2_k127_12225026_3 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001879 282.0
CH2_k127_12225026_4 PIN domain K07065 - - 0.00000000000000000000000000000000000000000005393 163.0
CH2_k127_12225026_5 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000000000002601 153.0
CH2_k127_12225026_6 Membrane - - - 0.00000000000000000000000000000000000000006246 162.0
CH2_k127_12225026_7 - - - - 0.000000000000000000000000000004623 123.0
CH2_k127_12225026_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000001835 102.0
CH2_k127_12225026_9 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000004982 93.0
CH2_k127_12233338_0 Domain of unknown function (DUF1974) - - - 0.0 1075.0
CH2_k127_12233338_1 Enoyl-CoA hydratase/isomerase - - - 2.047e-316 988.0
CH2_k127_12233338_10 protein conserved in bacteria K01790 GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704 5.1.3.13 0.000000000000000000000002387 105.0
CH2_k127_12233338_2 glutamate--cysteine ligase - - - 2.141e-216 680.0
CH2_k127_12233338_3 succinylglutamate desuccinylase activity K05526 - 3.5.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 487.0
CH2_k127_12233338_4 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 426.0
CH2_k127_12233338_5 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001255 277.0
CH2_k127_12233338_6 Belongs to the UPF0260 family K09160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003403 253.0
CH2_k127_12233338_7 PFAM Polyketide cyclase dehydrase K16260 - - 0.000000000000000000000000000000000000000000000000000000000000000000001923 240.0
CH2_k127_12233338_8 - - - - 0.000000000000000000000000000000000000000006982 155.0
CH2_k127_12233338_9 Hypothetical methyltransferase - - - 0.0000000000000000000000000000000000000302 154.0
CH2_k127_12242457_0 PFAM Uncharacterised protein family (UPF0182) K09118 - - 0.0 1126.0
CH2_k127_12242457_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000005427 186.0
CH2_k127_12242457_3 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000009129 55.0
CH2_k127_12242457_4 protein with SCP PR1 domains - - - 0.00007884 45.0
CH2_k127_12257808_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000398 611.0
CH2_k127_12257808_1 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.0000000003601 61.0
CH2_k127_12259463_0 Nitrogen regulation K07712 - - 7.038e-223 700.0
CH2_k127_12259463_1 Signal transduction histidine kinase K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 476.0
CH2_k127_12259463_2 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000000000002003 223.0
CH2_k127_12259463_3 Radical SAM superfamily - - - 0.0000000000000000000000000004335 114.0
CH2_k127_12289131_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 552.0
CH2_k127_12289131_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007756 262.0
CH2_k127_12289131_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000002864 213.0
CH2_k127_12289131_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000699 145.0
CH2_k127_12289131_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000008284 109.0
CH2_k127_12289131_5 - - - - 0.0000000008418 59.0
CH2_k127_12289131_7 - - - - 0.000001495 49.0
CH2_k127_12325613_0 Phage terminase large subunit (GpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 525.0
CH2_k127_12353041_0 ATP-dependent Clp protease, ATP-binding subunit ClpA K03694 - - 0.0 1151.0
CH2_k127_12353041_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 9.606e-318 979.0
CH2_k127_12353041_10 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000000000000000692 122.0
CH2_k127_12353041_11 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000002803 95.0
CH2_k127_12353041_12 succinate dehydrogenase, hydrophobic membrane anchor K00242 - - 0.0000000000000000008066 91.0
CH2_k127_12353041_13 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000007631 80.0
CH2_k127_12353041_14 - K19168 - - 0.0000003198 57.0
CH2_k127_12353041_15 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.0005938 46.0
CH2_k127_12353041_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 2.287e-211 663.0
CH2_k127_12353041_3 Succinate dehydrogenase fumarate reductase K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 440.0
CH2_k127_12353041_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 413.0
CH2_k127_12353041_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007505 402.0
CH2_k127_12353041_6 PFAM Sulphur oxidation protein SoxZ K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 334.0
CH2_k127_12353041_7 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000000001924 180.0
CH2_k127_12353041_8 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000001288 177.0
CH2_k127_12353041_9 - - - - 0.000000000000000000000000000000000002495 156.0
CH2_k127_12369709_0 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 426.0
CH2_k127_12369709_1 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006238 421.0
CH2_k127_12369709_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 319.0
CH2_k127_12369709_3 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001633 248.0
CH2_k127_12369709_4 Cysteine desulfurase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000003024 222.0
CH2_k127_12369709_5 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000007638 133.0
CH2_k127_1237699_0 transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 315.0
CH2_k127_1237699_1 acetyltransferase, isoleucine patch superfamily K08280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001825 281.0
CH2_k127_1237699_2 Transposase and inactivated derivatives K07497 - - 0.000000000000000000000000000000000000000000000002361 178.0
CH2_k127_1237699_3 transposition - - - 0.0000000000000000000000000000000000019 138.0
CH2_k127_1237699_4 - - - - 0.00000000000000000000000000000000001573 138.0
CH2_k127_12399420_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1067.0
CH2_k127_12399420_1 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 496.0
CH2_k127_12399420_2 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 428.0
CH2_k127_12399420_3 Protein of unknown function (DUF455) - - - 0.00000000000000000005006 91.0
CH2_k127_12399420_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000009011 85.0
CH2_k127_12456308_0 Zeta toxin - - - 1.579e-317 986.0
CH2_k127_12456308_1 PFAM PhoH-like protein K07175 - - 2.138e-242 755.0
CH2_k127_12456308_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 477.0
CH2_k127_12456308_3 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000002445 124.0
CH2_k127_12456308_4 PFAM Excalibur calcium-binding domain - - - 0.0000000000000001869 85.0
CH2_k127_12740451_0 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 357.0
CH2_k127_12740451_1 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005637 246.0
CH2_k127_12740451_2 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000335 221.0
CH2_k127_12740451_3 - - - - 0.000000000000000000000000000000000000000000003336 173.0
CH2_k127_12740451_4 Belongs to the GcvT family K06980 - - 0.000000000000000000000000002537 116.0
CH2_k127_12740451_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000965 86.0
CH2_k127_1274186_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 - 1.12.1.2 2.666e-290 895.0
CH2_k127_1274186_1 Putative peptidoglycan binding domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 480.0
CH2_k127_1274186_2 exporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006634 454.0
CH2_k127_1274186_3 hydrogenase maturation protease - - - 0.0000000000000000000000000000000000000000000007005 172.0
CH2_k127_1274186_4 NUDIX domain - - - 0.00000000000000000000000000000000000000000001698 166.0
CH2_k127_1274186_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000002064 109.0
CH2_k127_1274186_6 PFAM Cytochrome C - - - 0.000000000000002988 78.0
CH2_k127_12815257_0 Lipase maturation factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 404.0
CH2_k127_12815257_1 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 380.0
CH2_k127_12815257_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000002481 155.0
CH2_k127_12831978_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1158.0
CH2_k127_12831978_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0008150,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0042546,GO:0044085,GO:0071554,GO:0071840 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 442.0
CH2_k127_12831978_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 342.0
CH2_k127_12831978_3 Protein of unknown function (DUF2380) - - - 0.000000000000000000000000000000000000000000000000000000006776 205.0
CH2_k127_12831978_4 Chromosome Partitioning - - - 0.0000000000000000533 83.0
CH2_k127_12831978_5 Protein of unknown function (DUF1778) - - - 0.00000000000002071 83.0
CH2_k127_12850962_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1173.0
CH2_k127_12850962_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.004e-296 915.0
CH2_k127_12850962_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 303.0
CH2_k127_12850962_3 membrane transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 289.0
CH2_k127_12850962_4 PFAM Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004062 246.0
CH2_k127_12850962_5 SMART Cold shock protein K03704 - - 0.0000000000000000000000000000001145 124.0
CH2_k127_12850962_6 Mechanosensitive ion channel K05802 - - 0.00000000000000001801 83.0
CH2_k127_13021854_0 Protein of unknown function (DUF1631) - - - 3.127e-318 1016.0
CH2_k127_13021854_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.598e-302 936.0
CH2_k127_13021854_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.511e-259 805.0
CH2_k127_13021854_3 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 4.598e-220 686.0
CH2_k127_13021854_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 440.0
CH2_k127_13021854_5 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000000000001636 259.0
CH2_k127_13021854_6 PFAM Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000000000000009086 203.0
CH2_k127_13021854_7 Sporulation related domain K03749 - - 0.00000000000001603 76.0
CH2_k127_13054343_0 SMART HTH transcriptional regulator, Crp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 382.0
CH2_k127_13054343_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 344.0
CH2_k127_13054343_3 CsbD-like - - - 0.00000000000000000002215 93.0
CH2_k127_13054343_4 - - - - 0.0000000000000007195 81.0
CH2_k127_13054343_5 Protein of unknown function (DUF3096) - - - 0.000000000000002106 76.0
CH2_k127_1354441_0 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 496.0
CH2_k127_1354441_1 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000004959 192.0
CH2_k127_1354441_2 Putative restriction endonuclease - - - 0.00000000000000004007 83.0
CH2_k127_1354441_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000001564 78.0
CH2_k127_136546_0 ATPase, AAA K07478 - - 6.011e-218 682.0
CH2_k127_136546_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 439.0
CH2_k127_136546_2 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 346.0
CH2_k127_136546_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005434 265.0
CH2_k127_136546_4 2OG-Fe(II) oxygenase K07394 - - 0.0000000000000000000000000000000000000000000000000000000000000004313 227.0
CH2_k127_1366009_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.768e-247 767.0
CH2_k127_1366009_1 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0044271,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 526.0
CH2_k127_1366009_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 486.0
CH2_k127_1366009_3 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 469.0
CH2_k127_1366009_4 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 465.0
CH2_k127_1366009_5 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 377.0
CH2_k127_1366009_6 NfeD-like C-terminal, partner-binding K07340 - - 0.0000000000000000000000000000000000000000000000000000001259 198.0
CH2_k127_1366009_7 - - - - 0.00000000000525 70.0
CH2_k127_1393970_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 9.072e-249 771.0
CH2_k127_1393970_1 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 597.0
CH2_k127_1393970_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000007562 263.0
CH2_k127_1393970_3 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000003145 91.0
CH2_k127_1393970_4 PFAM Uncharacterised protein family (UPF0150) - - - 0.000000000005829 68.0
CH2_k127_141592_0 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 354.0
CH2_k127_141592_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005573 265.0
CH2_k127_141592_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000005269 206.0
CH2_k127_141592_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000004858 193.0
CH2_k127_141592_4 PFAM Lipid A Biosynthesis N-terminal - - - 0.00000000000000000000000000000000000003866 147.0
CH2_k127_141592_5 PFAM Integrase core domain - - - 0.000000000002038 68.0
CH2_k127_1425680_0 Peptidase family M3 K01414 - 3.4.24.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 518.0
CH2_k127_1425680_1 type II III secretion system K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001312 276.0
CH2_k127_1471048_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 452.0
CH2_k127_1471048_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 438.0
CH2_k127_1471048_3 Pentapeptide repeats (9 copies) - - - 0.0000272 47.0
CH2_k127_1581001_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008882,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0070566,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.42,2.7.7.89 0.0 1151.0
CH2_k127_1581001_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 561.0
CH2_k127_1581001_2 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 511.0
CH2_k127_1581001_3 von Willebrand factor, type A K07114 - - 0.0000000000001028 74.0
CH2_k127_1595765_0 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 391.0
CH2_k127_1595765_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005383 249.0
CH2_k127_1595765_2 PFAM Flavin - - - 0.000000000000000000000000000000000000000000000000000007623 193.0
CH2_k127_1595765_3 COG0575 CDP-diglyceride synthetase - - - 0.0000000000000000000000000000000000000000005124 162.0
CH2_k127_1595765_4 Domain of unknown function (DUF4153) - - - 0.00000000000002515 76.0
CH2_k127_1619890_0 PFAM Transposase IS66 family K07484 - - 1.145e-259 801.0
CH2_k127_1619890_1 Belongs to the OprB family K07267 - - 0.0000002805 57.0
CH2_k127_1621644_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 2.712e-313 968.0
CH2_k127_1621644_1 Ion channel - - - 0.0000000000000000000000000000000000001799 150.0
CH2_k127_1648261_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.103e-226 707.0
CH2_k127_1648261_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 9.618e-223 705.0
CH2_k127_1648261_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 490.0
CH2_k127_1648261_3 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006186 239.0
CH2_k127_1648261_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000002133 206.0
CH2_k127_1648261_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000000000000011 150.0
CH2_k127_1648261_6 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000006933 77.0
CH2_k127_1694753_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 497.0
CH2_k127_1694753_1 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008427 279.0
CH2_k127_1694753_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000007 65.0
CH2_k127_1694753_3 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.00000001023 56.0
CH2_k127_1748519_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 5.483e-238 737.0
CH2_k127_1748519_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000001521 224.0
CH2_k127_1748519_2 Protein of unknown function (DUF2818) - - - 0.00000000000000000000000005451 115.0
CH2_k127_179650_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 603.0
CH2_k127_179650_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 537.0
CH2_k127_179650_2 TIGRFAM Lipopolysaccharide heptosyltransferase II K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 476.0
CH2_k127_179650_3 TIGRFAM lipopolysaccharide heptosyltransferase I K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 446.0
CH2_k127_179650_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000338 146.0
CH2_k127_1868488_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1541.0
CH2_k127_1868488_1 COG1651 Protein-disulfide isomerase K21990 - - 0.0000000000000000000000000000000000000000001019 169.0
CH2_k127_1885215_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.455e-237 737.0
CH2_k127_1885215_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.149e-234 730.0
CH2_k127_1885215_10 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 331.0
CH2_k127_1885215_11 DNA polymerase III, delta' K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 324.0
CH2_k127_1885215_12 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004874 277.0
CH2_k127_1885215_13 PFAM Type IV pilus assembly PilZ K02676 - - 0.0000000000000000000000000000000000000000000000000000008006 196.0
CH2_k127_1885215_14 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000005152 168.0
CH2_k127_1885215_15 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000007517 134.0
CH2_k127_1885215_16 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000008493 133.0
CH2_k127_1885215_17 Multicopper K04753 - - 0.00000000000000000000001128 101.0
CH2_k127_1885215_18 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000000009891 98.0
CH2_k127_1885215_19 - - - - 0.0000000000009776 70.0
CH2_k127_1885215_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 577.0
CH2_k127_1885215_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 505.0
CH2_k127_1885215_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 498.0
CH2_k127_1885215_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 462.0
CH2_k127_1885215_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 417.0
CH2_k127_1885215_7 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 403.0
CH2_k127_1885215_8 3-oxoacyl-(Acyl-carrier-protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 394.0
CH2_k127_1885215_9 PFAM Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 392.0
CH2_k127_1904148_0 - - - - 0.000000000000000000000000000000000000000000002591 181.0
CH2_k127_1904148_1 SEC-C Motif Domain Protein - - - 0.000000000000000000000000000000000000002141 163.0
CH2_k127_190797_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1453.0
CH2_k127_190797_1 pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 539.0
CH2_k127_190797_2 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 392.0
CH2_k127_190797_3 response regulator K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 302.0
CH2_k127_190797_4 Histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000419 244.0
CH2_k127_190797_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000004397 226.0
CH2_k127_190797_6 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000000001111 190.0
CH2_k127_190797_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000003039 190.0
CH2_k127_190797_8 PemK-like, MazF-like toxin of type II toxin-antitoxin system K18841 - - 0.0000000000000000000000000000000000000000000000000004768 185.0
CH2_k127_190797_9 PFAM SpoVT AbrB like domain - - - 0.00000000000000000000000000000000004148 136.0
CH2_k127_1954752_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 5.848e-271 846.0
CH2_k127_1954752_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 6.715e-249 775.0
CH2_k127_1954752_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008174 250.0
CH2_k127_1954752_11 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.000000000000000000000000000000000000000000000000000002339 195.0
CH2_k127_1954752_12 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000004058 131.0
CH2_k127_1954752_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.164e-248 773.0
CH2_k127_1954752_3 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 8.941e-200 625.0
CH2_k127_1954752_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 572.0
CH2_k127_1954752_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 497.0
CH2_k127_1954752_6 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 464.0
CH2_k127_1954752_7 TIGRFAM Lytic murein transglycosylase B K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 395.0
CH2_k127_1954752_8 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 321.0
CH2_k127_1954752_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 314.0
CH2_k127_1959583_0 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 485.0
CH2_k127_1959583_1 ethanolamine kinase activity K07251 - 2.7.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 455.0
CH2_k127_1959583_2 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001424 248.0
CH2_k127_1960322_0 Thymidine phosphorylase K00758 - 2.4.2.4 5.814e-276 856.0
CH2_k127_1960322_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 7.17e-242 752.0
CH2_k127_1960322_10 PFAM ATPase, F1 V1 A1 complex, alpha beta subunit, nucleotide-binding domain K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 315.0
CH2_k127_1960322_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 304.0
CH2_k127_1960322_12 pfam nudix K08312 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002566 248.0
CH2_k127_1960322_13 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000000000009347 202.0
CH2_k127_1960322_14 protein conserved in bacteria K09906 - - 0.000000000000000000000000000000000000000002713 162.0
CH2_k127_1960322_15 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000002327 150.0
CH2_k127_1960322_16 - - - - 0.000000000000000000000001781 109.0
CH2_k127_1960322_17 - - - - 0.00000000000007407 75.0
CH2_k127_1960322_18 - - - - 0.00000000002792 73.0
CH2_k127_1960322_2 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 2.037e-208 653.0
CH2_k127_1960322_3 TIGRFAM Pilus retraction protein PilT K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 597.0
CH2_k127_1960322_4 TIGRFAM Pilus retraction protein PilT K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 462.0
CH2_k127_1960322_5 A G-specific adenine glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 439.0
CH2_k127_1960322_6 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 414.0
CH2_k127_1960322_7 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 398.0
CH2_k127_1960322_8 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 366.0
CH2_k127_1960322_9 PFAM Haloacid dehalogenase-like hydrolase K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 320.0
CH2_k127_1981862_0 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 357.0
CH2_k127_1981862_1 Squalene epoxidase K00511 - 1.14.14.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 338.0
CH2_k127_1981862_2 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 290.0
CH2_k127_1981862_3 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000000004861 198.0
CH2_k127_1981862_4 Belongs to the terpene cyclase mutase family K01853 - 5.4.99.8 0.000000000000002002 76.0
CH2_k127_1981862_5 - - - - 0.000000111 59.0
CH2_k127_1982286_0 Aminotransferase class I and II - - - 1.654e-195 616.0
CH2_k127_1982286_1 phosphatase (DUF442) - - - 0.00000000000000000000000000000004621 128.0
CH2_k127_1982286_2 Superoxide dismutase K04565 - 1.15.1.1 0.000000000000000000000000000002326 122.0
CH2_k127_1982286_3 - - - - 0.0000000000006915 71.0
CH2_k127_2010362_0 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000000000000000000000005713 229.0
CH2_k127_2010362_1 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000001465 210.0
CH2_k127_2010362_2 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000009308 194.0
CH2_k127_2010362_3 PFAM Cytochrome d1 K19345 - - 0.00000000000000000000000000000000000000000000000002397 180.0
CH2_k127_2018575_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 559.0
CH2_k127_2018575_1 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 550.0
CH2_k127_2018575_10 Ribose 5-phosphate isomerase K01808 GO:0003674,GO:0003824,GO:0004751,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008786,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019313,GO:0019314,GO:0019316,GO:0019318,GO:0019320,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046367,GO:0071704,GO:1901575 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000924 267.0
CH2_k127_2018575_11 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005239 267.0
CH2_k127_2018575_12 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.000000000000000000000000000000000000000000000001769 182.0
CH2_k127_2018575_13 Rubredoxin - - - 0.000000000000000000000000000001032 121.0
CH2_k127_2018575_14 dehydratase - - - 0.0000000000000000000000000004406 118.0
CH2_k127_2018575_15 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) - - - 0.0000000000000307 76.0
CH2_k127_2018575_16 PFAM Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000001539 71.0
CH2_k127_2018575_17 - - - - 0.000001689 53.0
CH2_k127_2018575_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 520.0
CH2_k127_2018575_3 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 490.0
CH2_k127_2018575_4 signal peptide peptidase SppA K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 444.0
CH2_k127_2018575_5 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 364.0
CH2_k127_2018575_6 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 306.0
CH2_k127_2018575_7 Bacterial lipid A biosynthesis acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 301.0
CH2_k127_2018575_8 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 302.0
CH2_k127_2018575_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006887 269.0
CH2_k127_2020522_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.074e-313 966.0
CH2_k127_2020522_1 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 578.0
CH2_k127_2020522_10 PIN domain - - - 0.000000000000000000000000000000000000000000002082 167.0
CH2_k127_2020522_11 Regulatory protein, FmdB family - - - 0.0000000000000000000000000000000000000001236 151.0
CH2_k127_2020522_12 - - - - 0.00000000000000000000000001144 111.0
CH2_k127_2020522_13 - - - - 0.0004391 44.0
CH2_k127_2020522_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 513.0
CH2_k127_2020522_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 494.0
CH2_k127_2020522_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 475.0
CH2_k127_2020522_5 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 439.0
CH2_k127_2020522_6 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 331.0
CH2_k127_2020522_7 (Lipo)protein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 319.0
CH2_k127_2020522_8 Bacterial SH3 domain homologues K07184 - - 0.0000000000000000000000000000000000000000000000000000000004383 211.0
CH2_k127_2020522_9 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000007748 174.0
CH2_k127_2037717_0 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region K07640 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 467.0
CH2_k127_2037717_1 response regulator K07662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 291.0
CH2_k127_2037717_2 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000001479 223.0
CH2_k127_2047299_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 447.0
CH2_k127_2047299_1 Nucleoside H+ symporter K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 452.0
CH2_k127_2047299_2 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000009597 147.0
CH2_k127_2062556_0 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 523.0
CH2_k127_2062556_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 379.0
CH2_k127_2062556_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 296.0
CH2_k127_2062556_3 ABC transporter - - - 0.0000000000000000000000000000000000004519 140.0
CH2_k127_2062556_4 DbpA RNA binding domain - - - 0.00000000000000000000006869 106.0
CH2_k127_2091859_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.972e-224 702.0
CH2_k127_2091859_1 virion core protein (lumpy skin disease virus) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 462.0
CH2_k127_2091859_2 Transcription factor zinc-finger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009175 245.0
CH2_k127_2091859_3 toxin-antitoxin system toxin component, PIN family - - - 0.0000000000000000000000000000000000000000000000000000000000000102 218.0
CH2_k127_2091859_4 Ferredoxin - - - 0.000000000000000000000000000000000000000000003107 166.0
CH2_k127_2091859_5 C-terminal domain of 1-Cys peroxiredoxin - - - 0.000000000000000000000000000000000000000001304 157.0
CH2_k127_2091859_6 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0000000000000000000000000000000000000002112 150.0
CH2_k127_2091859_7 HicB family - - - 0.0000000000000000000000000000003524 123.0
CH2_k127_2091859_8 Protein of unknown function (DUF1640) - - - 0.0000000000000000004393 93.0
CH2_k127_2147112_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 374.0
CH2_k127_2147112_1 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000004093 206.0
CH2_k127_2191745_0 Catalyzes the synthesis of activated sulfate K00860,K00958 - 2.7.1.25,2.7.7.4 3.634e-263 825.0
CH2_k127_2191745_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 592.0
CH2_k127_2191745_2 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 413.0
CH2_k127_2191745_3 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 396.0
CH2_k127_2191745_4 PFAM Uncharacterised protein family UPF0079, ATPase bacteria K06925 - - 0.00000000000000000000000000000000000000000000000003489 182.0
CH2_k127_2202303_0 protein involved in exopolysaccharide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 586.0
CH2_k127_2202303_1 reductase 4Fe-4S K00381 - 1.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 475.0
CH2_k127_2202303_10 Mov34 MPN PAD-1 - - - 0.0000000000000000000000000000000000000000000000568 172.0
CH2_k127_2202303_11 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000008012 142.0
CH2_k127_2202303_12 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000001547 144.0
CH2_k127_2202303_13 Bacterial protein of unknown function (DUF934) - - - 0.000000000000000000000000001158 117.0
CH2_k127_2202303_14 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000002041 78.0
CH2_k127_2202303_2 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 462.0
CH2_k127_2202303_3 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 456.0
CH2_k127_2202303_4 recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 424.0
CH2_k127_2202303_5 Acyl- acyl-carrier-protein --UDP-N-acetylglucosamine O-acyltransferase K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 404.0
CH2_k127_2202303_6 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009975 346.0
CH2_k127_2202303_7 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 314.0
CH2_k127_2202303_8 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000000001689 216.0
CH2_k127_2202303_9 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000003982 186.0
CH2_k127_2375114_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 6.838e-302 931.0
CH2_k127_2375114_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 5.764e-201 637.0
CH2_k127_2375114_10 RDD family - - - 0.0000000000000000000000000000000000000000000000000000001505 198.0
CH2_k127_2375114_11 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000002073 159.0
CH2_k127_2375114_12 PFAM DNA polymerase III chi subunit, HolC K02339 - 2.7.7.7 0.0000000000000000000000000000000000000003682 153.0
CH2_k127_2375114_14 - - - - 0.00000000000002518 75.0
CH2_k127_2375114_2 Aminotransferase, class I K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 602.0
CH2_k127_2375114_3 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 596.0
CH2_k127_2375114_4 Permease YjgP YjgQ K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 426.0
CH2_k127_2375114_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 377.0
CH2_k127_2375114_6 Permease YjgP YjgQ K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 379.0
CH2_k127_2375114_7 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 351.0
CH2_k127_2375114_8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 347.0
CH2_k127_2375114_9 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000002645 214.0
CH2_k127_2413822_0 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 552.0
CH2_k127_2413822_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000007688 178.0
CH2_k127_2423157_0 Arginine deiminase K01478 - 3.5.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 317.0
CH2_k127_2423157_1 Transposase - - - 0.000000000000000000363 90.0
CH2_k127_2423157_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.00000004023 57.0
CH2_k127_2433847_0 PFAM Filamentation induced by cAMP death on - - - 5.033e-214 669.0
CH2_k127_2433847_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 293.0
CH2_k127_2433847_2 DDE superfamily endonuclease - - - 0.000001181 53.0
CH2_k127_250510_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 400.0
CH2_k127_250510_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 296.0
CH2_k127_2506912_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 432.0
CH2_k127_2506912_1 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 412.0
CH2_k127_2506912_2 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000597 260.0
CH2_k127_2544545_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0 1053.0
CH2_k127_2544545_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 4.903e-230 717.0
CH2_k127_2544545_2 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region - - - 6.55e-203 636.0
CH2_k127_2544545_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005546 387.0
CH2_k127_2544545_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000002963 204.0
CH2_k127_2544545_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000002037 188.0
CH2_k127_2544545_6 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000000000002427 71.0
CH2_k127_2544545_7 bile acid:sodium symporter activity K00041,K03453 - 1.1.1.58 0.000000002566 59.0
CH2_k127_254976_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 412.0
CH2_k127_254976_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 321.0
CH2_k127_254976_2 response to cobalt ion - - - 0.00000000000000000000000000000000000000000009887 160.0
CH2_k127_254976_3 - - - - 0.00000000000000000000000000000000376 137.0
CH2_k127_254976_4 Rubredoxin - - - 0.00000000000000000000000539 104.0
CH2_k127_2551351_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.54e-242 758.0
CH2_k127_2551351_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 4.668e-201 636.0
CH2_k127_2551351_2 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 317.0
CH2_k127_2551351_3 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004909 242.0
CH2_k127_2551351_4 COG0659 Sulfate permease and related transporters (MFS superfamily K03321 - - 0.000000000000000000000000000000000000000000000000006485 190.0
CH2_k127_2551351_5 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000003793 190.0
CH2_k127_2551351_6 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000004257 174.0
CH2_k127_2551351_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000001576 167.0
CH2_k127_257162_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.32e-246 767.0
CH2_k127_2620240_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.632e-242 755.0
CH2_k127_2620240_1 epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 495.0
CH2_k127_2620240_10 Putative restriction endonuclease - - - 0.000000000000001267 79.0
CH2_k127_2620240_11 TIGRFAM Thioredoxin K03672 - 1.8.1.8 0.00000000000001568 75.0
CH2_k127_2620240_2 PFAM PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 475.0
CH2_k127_2620240_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 435.0
CH2_k127_2620240_4 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 371.0
CH2_k127_2620240_5 heat shock protein DnaJ K05516 - - 0.00000000000000000000000000000000000000000000000000000000000003442 216.0
CH2_k127_2620240_6 - - - - 0.000000000000000000000000000000000000000000000000000000005363 204.0
CH2_k127_2620240_7 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000000000132 198.0
CH2_k127_2620240_8 protein conserved in bacteria K09912 - - 0.00000000000000000000000000000000000000000000001788 176.0
CH2_k127_2620240_9 MerR HTH family regulatory protein K18997 - - 0.00000000000000000000000000004652 119.0
CH2_k127_2625699_0 MoeA N-terminal region (domain I K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 470.0
CH2_k127_2625699_1 PFAM Aminotransferase, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 333.0
CH2_k127_2625699_2 TIGRFAM RNA polymerase sigma factor RpoS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 319.0
CH2_k127_2625699_3 molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.00000000000000000000000000000000000000000000000000000000000000005784 227.0
CH2_k127_2625699_4 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000004885 113.0
CH2_k127_2625699_5 Peptidase, M23 family K06194 - - 0.00000000004805 64.0
CH2_k127_2625699_6 Peptidase family M23 - - - 0.0000000003937 61.0
CH2_k127_2675999_0 Required for chromosome condensation and partitioning K03529 - - 4.764e-275 873.0
CH2_k127_2675999_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 384.0
CH2_k127_2675999_2 Copper resistance protein B precursor (CopB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 364.0
CH2_k127_2675999_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000141 248.0
CH2_k127_2675999_4 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000001042 183.0
CH2_k127_2847614_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 5.676e-246 767.0
CH2_k127_2857331_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 3.267e-301 933.0
CH2_k127_2857331_1 Oxidoreductase NAD-binding domain K00523,K21832 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 431.0
CH2_k127_2857331_10 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000001301 175.0
CH2_k127_2857331_11 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000001436 168.0
CH2_k127_2857331_12 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000008868 134.0
CH2_k127_2857331_13 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.000000000000000016 82.0
CH2_k127_2857331_2 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 411.0
CH2_k127_2857331_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 325.0
CH2_k127_2857331_4 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 319.0
CH2_k127_2857331_5 COG2206 HD-GYP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004075 274.0
CH2_k127_2857331_6 Glycosyl transferases, related to UDP-glucuronosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005988 268.0
CH2_k127_2857331_7 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000004429 246.0
CH2_k127_2857331_8 Protein of unknown function (DUF3455) - - - 0.00000000000000000000000000000000000000000000000764 176.0
CH2_k127_2857331_9 Sporulation related domain - - - 0.0000000000000000000000000000000000000000006797 163.0
CH2_k127_2860495_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1298.0
CH2_k127_2860495_1 MreB/Mbl protein - - - 2.353e-273 850.0
CH2_k127_2860495_2 TonB-dependent receptor K02014 - - 5.832e-258 811.0
CH2_k127_2860495_3 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 441.0
CH2_k127_2860495_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 328.0
CH2_k127_2860495_5 GrpE K03687 - - 0.0000000000000000000000000000000000000000000000000000000002458 209.0
CH2_k127_2860495_7 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.000001438 50.0
CH2_k127_2914977_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 9.383e-211 664.0
CH2_k127_2914977_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 394.0
CH2_k127_2914977_2 TIGRFAM Lytic murein transglycosylase B K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 297.0
CH2_k127_2996334_0 ABC transporter K02471 - - 3.745e-233 734.0
CH2_k127_2996334_1 GMC oxidoreductase - - - 3.443e-221 692.0
CH2_k127_2996334_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000001422 54.0
CH2_k127_302707_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.702e-301 927.0
CH2_k127_302707_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 567.0
CH2_k127_302707_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000000000000002062 165.0
CH2_k127_302707_11 TIGRFAM Addiction module toxin, RelE StbE - - - 0.00000000000000000000000000000000000000001084 154.0
CH2_k127_302707_12 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000000000000000003181 144.0
CH2_k127_302707_13 ATP synthase I chain K02116 - - 0.00000000000000000000000000000004829 128.0
CH2_k127_302707_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 465.0
CH2_k127_302707_3 helicase Cas3 K07012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 458.0
CH2_k127_302707_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 449.0
CH2_k127_302707_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 443.0
CH2_k127_302707_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007695 278.0
CH2_k127_302707_7 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005524 273.0
CH2_k127_302707_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000000000004602 220.0
CH2_k127_302707_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000001963 201.0
CH2_k127_3033320_0 - - - - 0.000000000000000000000000000000000000000002988 158.0
CH2_k127_3033320_1 Belongs to the bacterial solute-binding protein 3 family K09969 - - 0.0000000000000000000000000000000000003495 147.0
CH2_k127_3033320_2 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000000005596 131.0
CH2_k127_3033320_3 Glycine-zipper domain - - - 0.00000000000000000000818 94.0
CH2_k127_3033320_4 META domain K09914 - - 0.00000000000000005126 87.0
CH2_k127_3033320_5 Conserved Protein - - - 0.000000007407 57.0
CH2_k127_3048776_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 1.475e-237 745.0
CH2_k127_3048776_1 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 488.0
CH2_k127_3048776_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 363.0
CH2_k127_3048776_3 universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 352.0
CH2_k127_3048776_4 - - - - 0.000000000000000000000000000000000000000000005248 162.0
CH2_k127_3048776_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000005307 51.0
CH2_k127_3162964_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000002924 187.0
CH2_k127_3162964_1 radical SAM domain protein - - - 0.0000000000000000000001753 108.0
CH2_k127_3162964_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000003737 94.0
CH2_k127_3162964_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000003778 56.0
CH2_k127_3240693_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1672.0
CH2_k127_3240693_1 alpha beta alpha domain I K01835 - 5.4.2.2 5.838e-281 870.0
CH2_k127_3240693_10 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 361.0
CH2_k127_3240693_11 PFAM YkuD domain K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 355.0
CH2_k127_3240693_12 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 309.0
CH2_k127_3240693_13 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 309.0
CH2_k127_3240693_14 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003217 263.0
CH2_k127_3240693_15 Thioredoxin-like [2Fe-2S] ferredoxin K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003376 243.0
CH2_k127_3240693_16 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002228 225.0
CH2_k127_3240693_17 Uracil DNA glycosylase superfamily - - - 0.000000000000000000000000000000000000000000000000000232 189.0
CH2_k127_3240693_18 - - - - 0.0000000000000000000000000000000000000866 146.0
CH2_k127_3240693_19 Alanine-zipper, major outer membrane lipoprotein - - - 0.0000000000000000000002003 99.0
CH2_k127_3240693_2 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00124 - - 6.652e-276 854.0
CH2_k127_3240693_20 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.000000000000000000002043 95.0
CH2_k127_3240693_21 PFAM BFD-like 2Fe-2S -binding K02192 - - 0.000000000000000001995 86.0
CH2_k127_3240693_3 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 3.118e-241 754.0
CH2_k127_3240693_4 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 609.0
CH2_k127_3240693_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 569.0
CH2_k127_3240693_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 464.0
CH2_k127_3240693_7 May be involved in recombination K03554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 407.0
CH2_k127_3240693_8 ZIP Zinc transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 385.0
CH2_k127_3240693_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 382.0
CH2_k127_3257967_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 362.0
CH2_k127_3257967_1 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 338.0
CH2_k127_3257967_2 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 335.0
CH2_k127_3257967_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 313.0
CH2_k127_3257967_4 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000004522 222.0
CH2_k127_3257967_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000003348 102.0
CH2_k127_3257967_6 PFAM Metal-dependent phosphohydrolase, HD region, subdomain K08722 - 3.1.3.89 0.0001283 47.0
CH2_k127_326540_0 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 1.796e-276 858.0
CH2_k127_326540_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000001639 138.0
CH2_k127_3303081_0 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0 1978.0
CH2_k127_3303081_1 Vitamin K-dependent gamma-carboxylase - - - 5.289e-256 804.0
CH2_k127_3303081_2 - - - - 1.084e-202 642.0
CH2_k127_3303081_3 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 537.0
CH2_k127_3303081_4 - - - - 0.00000000000000000000004163 103.0
CH2_k127_3303081_5 - - - - 0.0000000000000000058 89.0
CH2_k127_3303081_7 Protein of unknown function (DUF2970) - - - 0.00000001415 57.0
CH2_k127_3328389_0 COG0277 FAD FMN-containing dehydrogenases K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 394.0
CH2_k127_3328389_1 Peptidoglycan-binding protein, CsiV - - - 0.00000000000000000000000001131 118.0
CH2_k127_3328389_2 Glycolate oxidase, iron-sulfur subunit K11473 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - 0.00000000000000000003632 90.0
CH2_k127_3328389_3 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000003992 79.0
CH2_k127_3361879_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 1.731e-302 930.0
CH2_k127_3361879_1 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 406.0
CH2_k127_3361879_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 333.0
CH2_k127_3361879_3 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002001 262.0
CH2_k127_3361879_4 Cellulose biosynthesis protein BcsQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000004057 237.0
CH2_k127_3361879_5 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000002251 224.0
CH2_k127_337873_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.784e-239 749.0
CH2_k127_337873_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 394.0
CH2_k127_337873_2 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 392.0
CH2_k127_337873_3 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000002904 252.0
CH2_k127_337873_4 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0004035 45.0
CH2_k127_3388021_0 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 432.0
CH2_k127_3388021_1 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 406.0
CH2_k127_3391248_0 Polynucleotide adenylyltransferase K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001101 284.0
CH2_k127_3391248_1 Protein of unknown function (DUF1348) K09958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001323 259.0
CH2_k127_3392723_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 565.0
CH2_k127_3392723_1 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 411.0
CH2_k127_3392723_2 Uncharacterized protein conserved in bacteria (DUF2333) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 410.0
CH2_k127_3392723_3 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 321.0
CH2_k127_3392723_4 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005316 281.0
CH2_k127_3392723_5 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000006971 122.0
CH2_k127_3392723_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000003351 94.0
CH2_k127_3405254_0 Heat shock 70 kDa protein K04043 - - 0.0 1086.0
CH2_k127_3405254_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 2.834e-195 614.0
CH2_k127_3405254_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000001328 166.0
CH2_k127_3407400_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 4.15e-283 876.0
CH2_k127_3407400_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 332.0
CH2_k127_3407400_2 Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000001206 210.0
CH2_k127_3407400_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.000000000000000000000003229 104.0
CH2_k127_3436277_0 TIGRFAM Formylmethanofuran dehydrogenase, subunit A K00200 - 1.2.7.12 3.653e-221 688.0
CH2_k127_3436277_1 TIGRFAM formylmethanofuran dehydrogenase subunit B K00201 - 1.2.7.12 1.895e-205 645.0
CH2_k127_3436277_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0002758 45.0
CH2_k127_3467858_0 Iron-containing alcohol dehydrogenase - - - 8.246e-220 685.0
CH2_k127_3467858_1 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 413.0
CH2_k127_3467858_2 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000000000003432 191.0
CH2_k127_3468463_0 MacB-like periplasmic core domain K02004 - - 5.109e-245 782.0
CH2_k127_3468463_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.143e-235 743.0
CH2_k127_3468463_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004885 277.0
CH2_k127_3468463_3 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001439 273.0
CH2_k127_3468463_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004432 238.0
CH2_k127_3468463_5 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.00000000000000000000000000000000000000000000000000000000009454 205.0
CH2_k127_3468463_6 Lipocalin-like domain - - - 0.0000000000000000000000000000001022 128.0
CH2_k127_3478795_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1318.0
CH2_k127_3478795_1 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 3.556e-257 803.0
CH2_k127_3478795_2 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 583.0
CH2_k127_3478795_3 glutamate decarboxylase activity K01590 - 4.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 478.0
CH2_k127_3478795_4 COG0659 Sulfate permease and related transporters (MFS superfamily K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 329.0
CH2_k127_3478795_5 PFAM amino acid-binding ACT domain protein - - - 0.00000000006352 68.0
CH2_k127_3478795_6 Belongs to the ArsC family K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.00000002666 55.0
CH2_k127_3515086_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.153e-258 802.0
CH2_k127_3515086_1 Belongs to the peptidase M24B family K01262 - 3.4.11.9 2.175e-230 718.0
CH2_k127_3515086_2 glucosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 459.0
CH2_k127_3515086_3 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 316.0
CH2_k127_3515086_4 Belongs to the UPF0149 family K09895 - - 0.000000000000000000000000000000000000000000000001503 179.0
CH2_k127_3515086_5 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000004098 109.0
CH2_k127_3515086_6 - K09892 - - 0.00000000000000001431 85.0
CH2_k127_3521543_0 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 469.0
CH2_k127_3521543_1 Sporulation related domain K03749 - - 0.0000000000003956 78.0
CH2_k127_3578752_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1084.0
CH2_k127_3578752_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 565.0
CH2_k127_3578752_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 423.0
CH2_k127_3578752_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004562 272.0
CH2_k127_3578752_4 PFAM HTH transcriptional regulator, MerR - - - 0.000000000000000000000000000000000000000000000000000000000000002711 218.0
CH2_k127_3578752_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000002149 192.0
CH2_k127_3578752_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000002714 147.0
CH2_k127_3578752_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000000006391 116.0
CH2_k127_3578752_8 dehydrogenase - - - 0.00002042 46.0
CH2_k127_358540_0 AMP-binding enzyme K01897 - 6.2.1.3 1.778e-249 793.0
CH2_k127_358540_1 Belongs to the RtcB family K14415 - 6.5.1.3 1.377e-243 758.0
CH2_k127_358540_10 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000001123 146.0
CH2_k127_358540_11 - - - - 0.00000000000000000006927 93.0
CH2_k127_358540_12 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K04085 - - 0.000000000000000002783 86.0
CH2_k127_358540_13 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000408 59.0
CH2_k127_358540_2 RNA helicase K11927 - 3.6.4.13 7.052e-202 636.0
CH2_k127_358540_3 Bacterial capsule synthesis protein PGA_cap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 608.0
CH2_k127_358540_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 313.0
CH2_k127_358540_5 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 297.0
CH2_k127_358540_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000237 205.0
CH2_k127_358540_7 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000000000000000004072 201.0
CH2_k127_358540_8 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000002004 177.0
CH2_k127_358540_9 Glycine-zipper domain - - - 0.00000000000000000000000000000000000000000000002015 173.0
CH2_k127_3595420_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 9.411e-253 788.0
CH2_k127_3595420_1 TIGRFAM Ammonia monooxygenase particulate methane monooxygenase, subunit B K10945 - - 1.2e-219 686.0
CH2_k127_3595420_10 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000003948 237.0
CH2_k127_3595420_11 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000003307 186.0
CH2_k127_3595420_12 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000001243 186.0
CH2_k127_3595420_13 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000000000006659 139.0
CH2_k127_3595420_14 - - - - 0.0000000000000000000000000000000001259 137.0
CH2_k127_3595420_15 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 - - 0.0000000000000000000000013 107.0
CH2_k127_3595420_16 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000003291 63.0
CH2_k127_3595420_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.952e-209 666.0
CH2_k127_3595420_3 Belongs to the GARS family K01945 - 6.3.4.13 2.492e-201 634.0
CH2_k127_3595420_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 519.0
CH2_k127_3595420_5 methane monooxygenase, subunit C K10946 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 469.0
CH2_k127_3595420_6 TIGRFAM Ammonia monooxygenase particulate methane monooxygenase, subunit A K10944 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.18.3,1.14.99.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 448.0
CH2_k127_3595420_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 417.0
CH2_k127_3595420_8 Histidine kinase K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 287.0
CH2_k127_3595420_9 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000002069 258.0
CH2_k127_360688_0 synthase component I K01665 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 535.0
CH2_k127_360688_1 Protein of unknown function (DUF2959) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007927 243.0
CH2_k127_360688_2 Amino acid kinase family - - - 0.00000000000000000000000000000000000000003458 165.0
CH2_k127_360688_3 - - - - 0.00000000000000000000000000000003473 132.0
CH2_k127_360688_4 50S ribosome-binding GTPase - - - 0.0000000000000000000000002842 107.0
CH2_k127_3621970_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.0 1097.0
CH2_k127_3621970_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00819 - 2.6.1.13 2.316e-241 751.0
CH2_k127_3621970_2 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 2.235e-204 640.0
CH2_k127_3621970_3 PFAM Squalene phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 568.0
CH2_k127_3621970_4 PFAM Toluene tolerance K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001421 270.0
CH2_k127_3621970_5 TIGRFAM Hopanoid-associated phosphorylase K01243 - 3.2.2.9 0.0000000000000000000000000000000000000000000000000001104 194.0
CH2_k127_3621970_6 CopC domain K07156 - - 0.0000000000000000000000000001433 120.0
CH2_k127_3625397_0 Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 6.748e-252 786.0
CH2_k127_3625397_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 475.0
CH2_k127_3625397_2 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 330.0
CH2_k127_3625397_3 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000006929 195.0
CH2_k127_3625397_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000000002057 169.0
CH2_k127_367965_0 ABC transporter transmembrane region - - - 0.0 1059.0
CH2_k127_367965_1 TIGRFAM type I secretion membrane fusion protein, HlyD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 593.0
CH2_k127_3735187_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 4.595e-314 965.0
CH2_k127_3735187_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 352.0
CH2_k127_3735187_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 295.0
CH2_k127_3735187_3 PIN domain - - - 0.0000000000000000000000000000003211 126.0
CH2_k127_3735187_4 Protein of unknown function (DUF455) - - - 0.000000000003251 68.0
CH2_k127_3735187_5 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000001547 53.0
CH2_k127_3736585_0 Multicopper oxidase K04753 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 451.0
CH2_k127_3736585_1 PFAM Binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000002226 76.0
CH2_k127_3778439_0 PFAM Regulator of K conductance, N-terminal K10716 - - 9.895e-195 624.0
CH2_k127_3778439_1 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor region K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 459.0
CH2_k127_3778439_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 360.0
CH2_k127_3778439_3 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 296.0
CH2_k127_3778439_4 PFAM Regulator of K conductance, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001619 275.0
CH2_k127_3778439_5 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000268 272.0
CH2_k127_3778439_6 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005278 267.0
CH2_k127_3778439_7 YGGT family K02221 - - 0.00000000000000000000000000000000000000000000000000000000000000000001693 242.0
CH2_k127_3778439_8 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000000000000000000000000000000001728 231.0
CH2_k127_3778439_9 TonB-dependent Receptor Plug - - - 0.0000000000000000000000000000000000000000000000000001788 189.0
CH2_k127_3789228_0 PFAM Multicopper oxidase - - - 6.036e-229 717.0
CH2_k127_3789228_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 527.0
CH2_k127_3789228_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 517.0
CH2_k127_3789228_3 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 432.0
CH2_k127_3789228_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 374.0
CH2_k127_3789228_5 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 292.0
CH2_k127_3789228_6 Prokaryotic glutathione synthetase, ATP-grasp domain K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 293.0
CH2_k127_3789228_7 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000004096 260.0
CH2_k127_3812505_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1562.0
CH2_k127_3812505_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 429.0
CH2_k127_3812505_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 387.0
CH2_k127_3812505_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 369.0
CH2_k127_3812505_4 Protein of unknown function (DUF3240) - - - 0.000000000000000000000000000000000000003897 149.0
CH2_k127_390046_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 556.0
CH2_k127_390046_1 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 290.0
CH2_k127_390046_2 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007952 250.0
CH2_k127_390046_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000003733 229.0
CH2_k127_390046_4 COG0457 FOG TPR repeat - - - 0.000000000000000000000000001445 125.0
CH2_k127_3966766_0 Uncharacterized protein conserved in bacteria (DUF2252) - - - 7.623e-208 655.0
CH2_k127_3966766_1 Peptidase dimerisation domain K13049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 470.0
CH2_k127_3966766_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008178 284.0
CH2_k127_3966766_3 cellular modified histidine biosynthetic process - - - 0.000000000000000000000000000000000000000000000005449 175.0
CH2_k127_3966766_4 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000001518 83.0
CH2_k127_3966766_5 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000005328 73.0
CH2_k127_3966766_6 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000001826 65.0
CH2_k127_3966766_7 Involved in initiation control of chromosome replication K07484 - - 0.0000000003932 62.0
CH2_k127_3966766_8 Carbohydrate-selective porin, OprB family K07267 - - 0.00002792 49.0
CH2_k127_4053756_0 Sulfatase K01130 - 3.1.6.1 8.779e-286 884.0
CH2_k127_4053756_1 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 466.0
CH2_k127_4053756_2 PFAM Carbohydrate-selective porin OprB K07267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 400.0
CH2_k127_4053756_4 - - - - 0.000000000000000000000000000008252 120.0
CH2_k127_4053756_5 - - - - 0.0000000000000000000193 96.0
CH2_k127_4053756_6 Cytochrome c554 and c-prime - - - 0.000000000002998 73.0
CH2_k127_4053756_7 Protein of unknown function (DUF3313) - - - 0.00000000000728 66.0
CH2_k127_4053756_8 Small-conductance mechanosensitive channel K05802 - - 0.0000002405 54.0
CH2_k127_4072471_0 UvrD-like helicase C-terminal domain K03654 - 3.6.4.12 4.526e-197 631.0
CH2_k127_4075882_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 562.0
CH2_k127_4075882_1 Lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 336.0
CH2_k127_4075882_2 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000006272 183.0
CH2_k127_4075882_3 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000667 133.0
CH2_k127_4117155_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01535 - 3.6.3.6 2.646e-274 849.0
CH2_k127_4144005_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1098.0
CH2_k127_4144005_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.248e-223 699.0
CH2_k127_4144005_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 451.0
CH2_k127_4144005_3 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 347.0
CH2_k127_4144005_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 308.0
CH2_k127_4144005_5 SCP-2 sterol transfer family K03690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001045 245.0
CH2_k127_4144005_6 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000001034 191.0
CH2_k127_4144005_7 - - - - 0.0000000000000000000000000007615 117.0
CH2_k127_4144005_8 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000005963 108.0
CH2_k127_4160233_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 9.309e-202 633.0
CH2_k127_4160233_1 heat shock protein DnaJ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 397.0
CH2_k127_4160233_2 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 370.0
CH2_k127_4160233_3 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 341.0
CH2_k127_4160233_4 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000003668 129.0
CH2_k127_4224230_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.435e-251 782.0
CH2_k127_4224230_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 605.0
CH2_k127_4224230_2 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 474.0
CH2_k127_4224230_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 381.0
CH2_k127_4224230_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000005345 111.0
CH2_k127_4228932_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 520.0
CH2_k127_4228932_1 ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 380.0
CH2_k127_4228932_2 TonB C terminal K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 316.0
CH2_k127_4228932_3 PFAM HopJ type III effector protein - - - 0.00000000000000000000000000003213 120.0
CH2_k127_4263831_0 Belongs to the peptidase S16 family - - - 0.0 1065.0
CH2_k127_4263831_1 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 430.0
CH2_k127_4263831_2 - - - - 0.00000000000000005435 86.0
CH2_k127_4263831_3 - - - - 0.0000000000000004233 82.0
CH2_k127_4263831_4 Cytochrome P460 - - - 0.00009347 49.0
CH2_k127_4263831_5 - - - - 0.0002839 44.0
CH2_k127_4266392_0 DEAD DEAH box K03724 - - 0.0 1297.0
CH2_k127_4266392_1 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000007412 206.0
CH2_k127_4267093_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.669e-228 713.0
CH2_k127_4267093_1 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 412.0
CH2_k127_4267093_2 - - - - 0.00000001583 59.0
CH2_k127_4268795_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 462.0
CH2_k127_4268795_1 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 444.0
CH2_k127_4268795_2 Sigma 54 modulation protein K05808 - - 0.00000000000000000000000000000000000000005041 153.0
CH2_k127_4269481_0 Protein of unknown function - - - 5.136e-271 878.0
CH2_k127_4269481_1 ribonuclease, Rne Rng family K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 457.0
CH2_k127_4269481_2 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 456.0
CH2_k127_4269481_3 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000001467 149.0
CH2_k127_4281710_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 506.0
CH2_k127_4308592_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 2.211e-255 793.0
CH2_k127_4308592_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000008622 232.0
CH2_k127_4308592_2 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000000000002281 213.0
CH2_k127_4308592_3 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000004473 207.0
CH2_k127_4308592_4 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000003499 165.0
CH2_k127_4359343_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2246.0
CH2_k127_4359343_1 - - - - 0.000000000001977 67.0
CH2_k127_43833_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1138.0
CH2_k127_43833_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000001457 177.0
CH2_k127_4400901_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K18005 - 1.12.1.2 1.13e-293 910.0
CH2_k127_4400901_1 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 408.0
CH2_k127_4400901_2 PFAM NADH ubiquinone K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000002666 242.0
CH2_k127_4400901_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000004115 160.0
CH2_k127_4400901_4 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.00000000000000000000000000000000000003555 146.0
CH2_k127_4409750_0 PFAM Class II aldolase adducin K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 521.0
CH2_k127_4409750_1 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004757 271.0
CH2_k127_4409750_2 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000005997 243.0
CH2_k127_4409750_3 PFAM RNA-binding S4 K04762 - - 0.000000000000000000000000000000000000000000000000000000000000000000001276 237.0
CH2_k127_4443283_0 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 486.0
CH2_k127_4443283_1 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 300.0
CH2_k127_4443283_2 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005983 267.0
CH2_k127_4443283_3 YCII-related domain K09780 - - 0.00000000000000000000000000000000000000005128 153.0
CH2_k127_4443283_4 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000000000002062 126.0
CH2_k127_4467503_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 602.0
CH2_k127_4467503_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 541.0
CH2_k127_4467503_2 Belongs to the bacterial glucokinase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 353.0
CH2_k127_4467503_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006311 270.0
CH2_k127_4467503_4 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000001811 200.0
CH2_k127_4467503_5 Protein of unknown function, DUF - - - 0.000000000000000000000000000000000000000000000000000002823 194.0
CH2_k127_4467503_6 AMIN domain K02666 - - 0.000000000001779 67.0
CH2_k127_448813_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001251 229.0
CH2_k127_448813_1 FMN_bind - - - 0.000000000000000000000000000000000000000000000000000000000000000204 225.0
CH2_k127_448813_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000000000158 205.0
CH2_k127_448813_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000006494 134.0
CH2_k127_4502527_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00651 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0008899,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016750,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 607.0
CH2_k127_4502527_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 366.0
CH2_k127_4502527_2 Ferritin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004068 245.0
CH2_k127_4502527_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000001084 244.0
CH2_k127_4502527_4 deaminase zinc-binding - - - 0.0000000000000000000000000000000000000000000000000000000000005453 213.0
CH2_k127_4502527_5 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000001407 177.0
CH2_k127_4502527_6 Protein of unknown function, DUF393 - - - 0.0000000000000001509 80.0
CH2_k127_4502527_7 - - - - 0.00000000000007715 75.0
CH2_k127_4502527_8 Transposase IS66 family - - - 0.0000004685 54.0
CH2_k127_450748_0 PFAM Cytochrome - - - 4.92e-282 872.0
CH2_k127_450748_1 PFAM Cytochrome d1 K19345 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 396.0
CH2_k127_450748_2 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 314.0
CH2_k127_450748_3 PFAM HTH transcriptional regulator, MarR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003165 249.0
CH2_k127_450748_4 Domain of unknown function (DUF2024) - - - 0.00000000000000000000000000000000006938 136.0
CH2_k127_450748_5 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.000000000000000000000000000000001565 132.0
CH2_k127_450748_6 PFAM Cytochrome C - - - 0.000000000000000000000000000000296 125.0
CH2_k127_450748_7 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000001037 70.0
CH2_k127_450748_8 - - - - 0.000007018 51.0
CH2_k127_4567083_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1219.0
CH2_k127_4567083_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1136.0
CH2_k127_4567083_10 PFAM Ferrous iron transporter, FeoA subunit K04758 - - 0.000000000000000000000000000003507 121.0
CH2_k127_4567083_11 FeoC like transcriptional regulator - - - 0.00000000000000000000000000005827 119.0
CH2_k127_4567083_12 - - - - 0.000000000006733 74.0
CH2_k127_4567083_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1130.0
CH2_k127_4567083_3 AAA-like domain K06915 - - 3.676e-303 935.0
CH2_k127_4567083_4 fructose-bisphosphate aldolase, class II, yeast E. coli subtype K01624 - 4.1.2.13 2.474e-195 614.0
CH2_k127_4567083_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 573.0
CH2_k127_4567083_6 Belongs to the glutaminase family K01425 - 3.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 514.0
CH2_k127_4567083_7 PFAM Orotidine 5'-phosphate decarboxylase K08093 - 4.1.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 365.0
CH2_k127_4567083_8 SIS domain K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 302.0
CH2_k127_4567083_9 - - - - 0.000000000000000000000000000000000000001089 156.0
CH2_k127_4597816_0 Sucrose phosphate synthase, sucrose phosphatase-like K00696 - 2.4.1.14 0.0 1084.0
CH2_k127_4597816_1 SMART Glycosyl hydrolase, family 13, subfamily, catalytic region K05341 - 2.4.1.4 1.835e-314 965.0
CH2_k127_4597816_2 PFAM Carbohydrate purine kinase K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008801 432.0
CH2_k127_4597816_3 TIGRFAM HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 409.0
CH2_k127_4597816_4 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 320.0
CH2_k127_4597816_5 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007208 253.0
CH2_k127_4608264_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 532.0
CH2_k127_4608264_1 subfamily IB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 341.0
CH2_k127_4608264_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 286.0
CH2_k127_4608264_3 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000000001546 116.0
CH2_k127_4617953_0 PFAM Haloacid dehalogenase-like hydrolase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000001988 256.0
CH2_k127_4617953_1 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000000000004601 171.0
CH2_k127_4617953_2 Protein of unknown function (DUF4239) - - - 0.000000000000000000000000000000000000004654 159.0
CH2_k127_4617953_3 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000009825 111.0
CH2_k127_4624897_0 PFAM Glycosyl transferase family 2 - - - 0.0 1117.0
CH2_k127_4624897_1 Diguanylate cyclase - - - 2.16e-205 659.0
CH2_k127_4624897_2 ubiE/COQ5 methyltransferase family K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 372.0
CH2_k127_4624897_3 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 296.0
CH2_k127_4624897_4 antiporter K07301 - - 0.000000000000000000000000000000000000002906 151.0
CH2_k127_4686937_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 477.0
CH2_k127_4686937_1 PFAM Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 353.0
CH2_k127_4686937_2 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000013 271.0
CH2_k127_4693775_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.78e-285 892.0
CH2_k127_4693775_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 496.0
CH2_k127_4693775_2 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 480.0
CH2_k127_4693775_3 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 304.0
CH2_k127_4693775_4 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000002324 215.0
CH2_k127_4693775_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000584 198.0
CH2_k127_4693775_6 PFAM Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000007559 194.0
CH2_k127_4693775_7 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000008781 119.0
CH2_k127_4693775_8 COG0530 Ca2 Na antiporter K07301 - - 0.00000000002966 64.0
CH2_k127_4716457_0 Enoyl-CoA hydratase/isomerase - - - 1.143e-199 627.0
CH2_k127_4716457_1 DJ-1/PfpI family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 406.0
CH2_k127_4719864_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 585.0
CH2_k127_4719864_1 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 359.0
CH2_k127_4719864_2 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000487 183.0
CH2_k127_4721696_0 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 1.523e-273 859.0
CH2_k127_4721696_1 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 5.881e-202 636.0
CH2_k127_4721696_2 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 564.0
CH2_k127_4721696_3 Belongs to the IlvD Edd family K01690 - 4.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000003775 239.0
CH2_k127_4745912_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 4.757e-217 679.0
CH2_k127_4745912_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000003123 172.0
CH2_k127_4786605_0 PFAM Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1162.0
CH2_k127_4786605_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000006477 235.0
CH2_k127_4786605_2 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000641 201.0
CH2_k127_4786605_3 PFAM Sulphate transporter antisigma-factor antagonist STAS K04749 - - 0.00000000000000000000000000000000000000001584 156.0
CH2_k127_4786605_4 Bacterial toxin of type II toxin-antitoxin system, YafQ K19157 - - 0.00000000000000000000000000000000000002527 145.0
CH2_k127_4786605_6 RelB antitoxin K07473 - - 0.00002315 47.0
CH2_k127_4879084_0 Domain of unknown function (DUF4478) K06966 - 3.2.2.10 3.609e-253 798.0
CH2_k127_4879084_1 POT family K03305 - - 5.45e-197 623.0
CH2_k127_4879084_10 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000002056 242.0
CH2_k127_4879084_11 Cupin domain - - - 0.000000000000000000000000000000000000000000000009246 173.0
CH2_k127_4879084_12 - - - - 0.00000000001114 69.0
CH2_k127_4879084_13 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.0000000000466 65.0
CH2_k127_4879084_14 Domain of unknown function (DUF4381) - - - 0.0000000002855 64.0
CH2_k127_4879084_2 Cytochrome c-type biogenesis protein Ccs1 ResB K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 614.0
CH2_k127_4879084_3 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 516.0
CH2_k127_4879084_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 445.0
CH2_k127_4879084_5 short-chain dehydrogenase reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 396.0
CH2_k127_4879084_6 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 360.0
CH2_k127_4879084_7 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008217 292.0
CH2_k127_4879084_8 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 287.0
CH2_k127_4879084_9 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008723 279.0
CH2_k127_4881696_0 Acetyltransferase (GNAT) domain - - - 3.907e-244 760.0
CH2_k127_4881696_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002291 267.0
CH2_k127_4881696_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000002108 113.0
CH2_k127_4881696_3 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.00000000000838 68.0
CH2_k127_4881696_4 Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC K18704,K21285 - 2.7.8.14,2.7.8.44,2.7.8.47 0.000000001123 61.0
CH2_k127_489022_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1041.0
CH2_k127_489022_1 ABC1 family K03688 - - 2.17e-277 861.0
CH2_k127_489022_10 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000134 71.0
CH2_k127_489022_11 - - - - 0.0000004239 52.0
CH2_k127_489022_12 Heat shock protein DnaJ domain protein - - - 0.0006089 44.0
CH2_k127_489022_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 608.0
CH2_k127_489022_3 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 492.0
CH2_k127_489022_4 Belongs to the agmatine deiminase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 434.0
CH2_k127_489022_5 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000007766 241.0
CH2_k127_489022_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001173 231.0
CH2_k127_489022_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000003722 187.0
CH2_k127_489022_8 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000004001 168.0
CH2_k127_489022_9 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000001197 162.0
CH2_k127_4952989_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 583.0
CH2_k127_4952989_1 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 514.0
CH2_k127_4952989_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 514.0
CH2_k127_4952989_3 Protein of unknown function (DUF1318) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004274 236.0
CH2_k127_4952989_4 Predicted membrane protein (DUF2231) - - - 0.0000000000000000000000000000000000000000000000000000000000004377 217.0
CH2_k127_4952989_5 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000001764 126.0
CH2_k127_496902_0 Major facilitator superfamily - - - 7.757e-197 620.0
CH2_k127_496902_1 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 593.0
CH2_k127_497366_0 ABC transporter permease protein K02047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 398.0
CH2_k127_497366_1 sulfate transport system, permease K02046,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 346.0
CH2_k127_497366_2 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 331.0
CH2_k127_497366_3 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01535 - 3.6.3.6 0.00000000000000000000000000000000000000000000002397 175.0
CH2_k127_497366_4 - - - - 0.000000000000000000000000000000000000000003372 157.0
CH2_k127_5080592_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 575.0
CH2_k127_5080592_1 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 517.0
CH2_k127_5080592_2 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000001435 130.0
CH2_k127_5080592_3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K03574 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008413,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017110,GO:0030145,GO:0033554,GO:0034641,GO:0035539,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044715,GO:0044716,GO:0046483,GO:0046872,GO:0046914,GO:0047429,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.0000000000001598 71.0
CH2_k127_5092064_0 Sulfate adenylyltransferase subunit 2 K00957 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004779,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0070566,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 477.0
CH2_k127_5092064_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 357.0
CH2_k127_5092064_2 LysR substrate binding domain K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 309.0
CH2_k127_5092064_3 - - - - 0.00000000000004952 75.0
CH2_k127_5092064_4 - - - - 0.000000000001163 68.0
CH2_k127_514825_0 Pyridoxal-phosphate dependent enzyme K01505 - 3.5.99.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 364.0
CH2_k127_514825_1 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001622 243.0
CH2_k127_514825_2 Belongs to the P-Pant transferase superfamily K06133 - - 0.00000000000000000000000000000000000000000000008439 173.0
CH2_k127_514825_3 Methyltransferase domain - - - 0.0000000000000000000000004086 107.0
CH2_k127_5153977_0 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000251 134.0
CH2_k127_5153977_1 tryptophan synthase subunit beta - - - 0.000000000000000000000000001203 115.0
CH2_k127_5153977_2 response regulator - - - 0.0000000000000000008224 92.0
CH2_k127_5166164_0 Domain of unknown function (DUF1840) - - - 0.000000000000000000000000000001438 123.0
CH2_k127_5166164_2 - - - - 0.0000000000000000000001613 101.0
CH2_k127_5166164_3 - - - - 0.00000000000000000006045 94.0
CH2_k127_5166164_4 - - - - 0.000003987 58.0
CH2_k127_5166164_5 Rhodopirellula transposase DDE domain - - - 0.000009607 47.0
CH2_k127_5168853_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.4.2 2.707e-227 713.0
CH2_k127_5168853_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 544.0
CH2_k127_5168853_2 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 527.0
CH2_k127_5168853_3 Glycine cleavage system T protein K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 406.0
CH2_k127_5168853_4 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 361.0
CH2_k127_5168853_5 alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000009986 168.0
CH2_k127_5182133_0 Bacterial transglutaminase-like N-terminal - - - 0.0 1378.0
CH2_k127_5240040_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 6.472e-242 751.0
CH2_k127_5240040_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.497e-238 752.0
CH2_k127_5240040_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 2.844e-223 694.0
CH2_k127_5240040_3 PFAM Aminotransferase - - - 1.171e-197 620.0
CH2_k127_5240040_4 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 452.0
CH2_k127_5240040_5 Nad-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 362.0
CH2_k127_5303088_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 509.0
CH2_k127_5303088_1 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 367.0
CH2_k127_5303088_2 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 283.0
CH2_k127_5307257_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 340.0
CH2_k127_5307257_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 286.0
CH2_k127_5307257_2 small GTP-binding protein K06945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007314 252.0
CH2_k127_5328062_0 AIR synthase related protein, C-terminal K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 538.0
CH2_k127_5328062_1 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 460.0
CH2_k127_5328062_2 Tyrosine-protein kinase, subgroup, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 420.0
CH2_k127_5328062_3 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 341.0
CH2_k127_5328062_4 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000000000000000000000000000002839 158.0
CH2_k127_5328062_5 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000001874 127.0
CH2_k127_535184_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 445.0
CH2_k127_535184_1 - K09717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 317.0
CH2_k127_535184_2 subfamily IA, variant 3 - - - 0.0000000001344 63.0
CH2_k127_5356490_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 559.0
CH2_k127_5356490_1 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 380.0
CH2_k127_5356490_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002464 282.0
CH2_k127_5356490_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000001826 235.0
CH2_k127_5356490_4 Tol-Pal system-associated acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000003992 126.0
CH2_k127_5356490_5 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.00000000002976 66.0
CH2_k127_5359748_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 3.554e-313 965.0
CH2_k127_5365344_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 5.434e-269 835.0
CH2_k127_5365344_1 type IV, pilus assembly K02652 - - 1.499e-264 824.0
CH2_k127_5365344_2 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 601.0
CH2_k127_5365344_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 389.0
CH2_k127_5365344_4 TIGRFAM Mutator MutT protein K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 344.0
CH2_k127_5365344_5 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 320.0
CH2_k127_5365344_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000003902 208.0
CH2_k127_5385882_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.929e-277 856.0
CH2_k127_5385882_1 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000002259 207.0
CH2_k127_5385882_2 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000009615 153.0
CH2_k127_5385882_3 - - - - 0.00000000000000009939 84.0
CH2_k127_5385882_4 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.00000005281 59.0
CH2_k127_5401386_0 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 0.0 1450.0
CH2_k127_5401386_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1251.0
CH2_k127_5401386_2 4Fe-4S dicluster domain K00124 - - 3.711e-206 645.0
CH2_k127_5401386_3 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 595.0
CH2_k127_5401386_4 TIGRFAM phenazine biosynthesis K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 433.0
CH2_k127_5401386_5 TIGRFAM nitrite reductase NAD(P)H K00363 - 1.7.1.15 0.0000000000000000000000000000000000000000000000749 170.0
CH2_k127_541197_0 Cytochrome P450 K05917 - 1.14.13.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008692 608.0
CH2_k127_541197_1 Domain of unknown function (DUF389) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 319.0
CH2_k127_541197_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001798 255.0
CH2_k127_541197_3 - - - - 0.00000000000000005082 83.0
CH2_k127_5421209_0 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000000000000000000000000000000003309 177.0
CH2_k127_5421209_2 nitric oxide dioxygenase activity - - - 0.000000000000000000000000000005803 123.0
CH2_k127_5437128_0 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003289 259.0
CH2_k127_5437128_1 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000000000009413 195.0
CH2_k127_5437128_2 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000006474 122.0
CH2_k127_5437128_3 Glycine-zipper domain - - - 0.0000000000000000000007556 101.0
CH2_k127_5505623_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 552.0
CH2_k127_5505623_1 - - - - 0.000001979 49.0
CH2_k127_5645813_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009223 494.0
CH2_k127_5645813_1 alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 332.0
CH2_k127_5645813_2 Domain of unknown function (DUF4124) - - - 0.00000000136 59.0
CH2_k127_5660828_0 Large extracellular alpha-helical protein K06894 - - 8.333e-231 733.0
CH2_k127_5660828_1 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000006469 125.0
CH2_k127_5747095_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 481.0
CH2_k127_5747095_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 416.0
CH2_k127_5747095_2 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000002014 258.0
CH2_k127_5747095_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.000000006571 56.0
CH2_k127_575217_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.121e-245 765.0
CH2_k127_575217_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 5.631e-200 632.0
CH2_k127_575217_10 FHA domain - - - 0.000000000000000000000000000000000000000000000000000000000000001054 224.0
CH2_k127_575217_11 PFAM Class II aldolase - - - 0.000000000000000000000000000000000000000000000000000000000001161 217.0
CH2_k127_575217_12 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000004175 170.0
CH2_k127_575217_13 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000001735 130.0
CH2_k127_575217_14 ABC transporter K02003 - - 0.0000008931 52.0
CH2_k127_575217_15 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00005036 45.0
CH2_k127_575217_2 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 577.0
CH2_k127_575217_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 460.0
CH2_k127_575217_4 Belongs to the CinA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 451.0
CH2_k127_575217_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 435.0
CH2_k127_575217_6 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 386.0
CH2_k127_575217_7 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 361.0
CH2_k127_575217_8 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 315.0
CH2_k127_575217_9 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000002496 232.0
CH2_k127_5780780_0 membrane-bound lytic murein transglycosylase K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 520.0
CH2_k127_5780780_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003651 244.0
CH2_k127_5780780_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000008843 233.0
CH2_k127_58662_0 Carbamoyltransferase C-terminus K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 526.0
CH2_k127_58662_1 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 524.0
CH2_k127_58662_10 Transposase K07481 - - 0.00000397 49.0
CH2_k127_58662_2 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 521.0
CH2_k127_58662_3 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 418.0
CH2_k127_58662_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 324.0
CH2_k127_58662_5 PFAM Glycosyl transferase, family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005072 274.0
CH2_k127_58662_6 Peptidyl-prolyl cis-trans isomerase K01802,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000008403 228.0
CH2_k127_58662_7 Protein of unknown function (DUF3175) - - - 0.0000000000000000000000000000000000000002837 152.0
CH2_k127_58662_8 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000003218 138.0
CH2_k127_58662_9 - - - - 0.00000000000000000000000000007657 118.0
CH2_k127_5873169_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.087e-286 890.0
CH2_k127_5873169_1 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000002104 213.0
CH2_k127_5873169_2 Protein of unknown function (DUF2764) - - - 0.00000000002398 64.0
CH2_k127_5882045_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.389e-235 733.0
CH2_k127_5882045_1 SurA N-terminal domain K03770 - 5.2.1.8 7.658e-222 704.0
CH2_k127_5882045_2 Plant specific mitochondrial import receptor subunit TOM20 - - - 0.000000000000000000000000000000000000000000000000000001865 200.0
CH2_k127_5882045_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000003717 146.0
CH2_k127_5882045_4 - - - - 0.000000001036 63.0
CH2_k127_5920144_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.663e-219 683.0
CH2_k127_5920144_1 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 418.0
CH2_k127_5920144_2 Zinc-ribbon containing domain - - - 0.00000000000000000000000000000000000000000000003201 175.0
CH2_k127_5920144_3 2OG-Fe(II) oxygenase K07394 - - 0.00003161 49.0
CH2_k127_5944265_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1042.0
CH2_k127_5944265_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.065e-268 835.0
CH2_k127_5944265_10 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000004626 190.0
CH2_k127_5944265_11 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000003932 172.0
CH2_k127_5944265_12 Domain of unknown function (DUF4845) - - - 0.000000000000000000000000000000001092 133.0
CH2_k127_5944265_13 Anti sigma-E protein RseA, N-terminal domain K03597 - - 0.0000000000001566 77.0
CH2_k127_5944265_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 1.293e-198 630.0
CH2_k127_5944265_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 452.0
CH2_k127_5944265_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 409.0
CH2_k127_5944265_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 373.0
CH2_k127_5944265_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 301.0
CH2_k127_5944265_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 289.0
CH2_k127_5944265_8 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000002005 246.0
CH2_k127_5944265_9 MucB/RseB C-terminal domain K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000004358 241.0
CH2_k127_5979840_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 2.567e-249 782.0
CH2_k127_5979840_1 Methylene-tetrahydromethanopterin dehydrogenase, N-terminal K10714 - - 0.0000000000000000000000000000000000000000000000000000000000000001533 223.0
CH2_k127_6029677_0 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 - 4.1.1.38 0.0 1875.0
CH2_k127_6029677_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 2.351e-266 826.0
CH2_k127_6029677_2 Protein of unknown function (DUF1343) - - - 4.072e-225 702.0
CH2_k127_6029677_3 Sporulation related domain K16291 - - 2.585e-197 625.0
CH2_k127_6029677_4 - - - - 0.00000000000000000000000000000000000000000000001644 176.0
CH2_k127_6044433_0 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 555.0
CH2_k127_6044433_1 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001572 266.0
CH2_k127_6044433_2 TIGRFAM Hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 0.0000000000000000000000000000000000000006704 151.0
CH2_k127_6044433_3 Nitroreductase family - - - 0.000000000000000000000000000000000009825 138.0
CH2_k127_6090963_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 443.0
CH2_k127_6090963_1 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000001269 241.0
CH2_k127_6090963_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000233 228.0
CH2_k127_6090963_3 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000000000002162 214.0
CH2_k127_6090963_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000005137 138.0
CH2_k127_6090963_5 Bacterial DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000002365 136.0
CH2_k127_6121627_0 Beta-Casp domain K07576 - - 6.038e-215 675.0
CH2_k127_6121627_1 Belongs to the 5'-nucleotidase family - - - 7.708e-214 675.0
CH2_k127_6121627_2 - catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 0.0000000005575 66.0
CH2_k127_6162701_0 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0 1804.0
CH2_k127_6162701_1 TIGRFAM Hopanoid biosynthesis associated RND transporter like protein HpnN K07003 - - 1.671e-318 992.0
CH2_k127_6162701_10 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19 0.000000000000000000000000000000000000000000000000000000000000008037 221.0
CH2_k127_6162701_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000003387 194.0
CH2_k127_6162701_12 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000001369 188.0
CH2_k127_6162701_13 PFAM Phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.000000000000000000000000000000000000000000002313 166.0
CH2_k127_6162701_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000001006 112.0
CH2_k127_6162701_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705 - 0.000000000002877 68.0
CH2_k127_6162701_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 6.199e-214 673.0
CH2_k127_6162701_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 458.0
CH2_k127_6162701_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 415.0
CH2_k127_6162701_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 378.0
CH2_k127_6162701_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 358.0
CH2_k127_6162701_7 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 331.0
CH2_k127_6162701_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0000105,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 316.0
CH2_k127_6162701_9 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000003139 237.0
CH2_k127_6174648_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 2.216e-214 676.0
CH2_k127_6174648_1 TIGRFAM Signal transduction histidine kinase, phosphate regulon sensor PhoR K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 523.0
CH2_k127_6174648_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 445.0
CH2_k127_6174648_3 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 382.0
CH2_k127_6174648_4 Belongs to the DnaA family. HdA subfamily K10763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 292.0
CH2_k127_6174648_5 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 285.0
CH2_k127_6174648_6 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006624 274.0
CH2_k127_6174648_7 arsenate reductase K00537 - 1.20.4.1 0.0000000000000000000000000000000000000000000001447 170.0
CH2_k127_6174648_8 Predicted membrane protein (DUF2069) - - - 0.000000000000000000000003211 106.0
CH2_k127_6174648_9 - - - - 0.00000003455 59.0
CH2_k127_6175621_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 520.0
CH2_k127_6175621_1 Cation transporter/ATPase, N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 351.0
CH2_k127_6175621_2 - - - - 0.0000000000000000000000000003722 116.0
CH2_k127_6175621_3 - - - - 0.00000000004286 63.0
CH2_k127_617949_0 PFAM Sulfatase K01130 - 3.1.6.1 0.0 1360.0
CH2_k127_617949_1 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 589.0
CH2_k127_617949_10 DDE superfamily endonuclease - - - 0.00000000008473 64.0
CH2_k127_617949_11 META domain - - - 0.000000004934 63.0
CH2_k127_617949_12 Protein conserved in bacteria K09914 - - 0.0000008334 55.0
CH2_k127_617949_2 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 431.0
CH2_k127_617949_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001057 291.0
CH2_k127_617949_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004733 244.0
CH2_k127_617949_5 Protein of unknown function (DUF1214) - - - 0.000000000000000000000000000000000000000000000000000000000001898 215.0
CH2_k127_617949_6 Surface antigen K07278 - - 0.0000000000000000000000000000000000000008351 155.0
CH2_k127_617949_7 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.0000000000000000000000000000000001242 136.0
CH2_k127_617949_8 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.000000000000000000002109 96.0
CH2_k127_617949_9 Protein of unknown function (DUF1214) - - - 0.00000000000000002698 82.0
CH2_k127_6196903_0 PFAM ATPase, F1 V1 A1 complex, alpha beta subunit, nucleotide-binding domain K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 505.0
CH2_k127_6196903_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 395.0
CH2_k127_6196903_2 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.0000000000000000000000000000000000000000000007768 169.0
CH2_k127_6196903_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000006323 130.0
CH2_k127_6196903_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000002336 74.0
CH2_k127_6228888_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1047.0
CH2_k127_6228888_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 539.0
CH2_k127_6228888_2 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005887 528.0
CH2_k127_6258685_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 9.1e-322 1007.0
CH2_k127_6258685_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003824,GO:0004654,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.8 1.463e-315 975.0
CH2_k127_6258685_2 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 600.0
CH2_k127_6258685_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 322.0
CH2_k127_6258685_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000004657 143.0
CH2_k127_6258685_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000006509 126.0
CH2_k127_6267919_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.007e-301 929.0
CH2_k127_6267919_1 B12 binding domain - - - 1.036e-299 923.0
CH2_k127_6267919_2 Haem-degrading - - - 0.00000000000000000000000000000000000000000000002105 174.0
CH2_k127_6267919_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000000002137 149.0
CH2_k127_6267919_4 PIN domain - - - 0.0000000000000000000000000000000001989 132.0
CH2_k127_6267919_5 PFAM Plasmid stabilisation system - - - 0.00000001144 58.0
CH2_k127_6280261_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2383.0
CH2_k127_6280261_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2374.0
CH2_k127_6280261_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000000000000000000000002465 132.0
CH2_k127_6280261_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000009176 109.0
CH2_k127_6280261_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1236.0
CH2_k127_6280261_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 398.0
CH2_k127_6280261_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 324.0
CH2_k127_6280261_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000898 271.0
CH2_k127_6280261_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002666 263.0
CH2_k127_6280261_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000269 251.0
CH2_k127_6280261_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000008574 234.0
CH2_k127_6280261_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000007343 171.0
CH2_k127_6302071_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 490.0
CH2_k127_6302071_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001857 252.0
CH2_k127_6302071_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000002822 149.0
CH2_k127_6314029_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 3.283e-201 641.0
CH2_k127_6314029_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008919 387.0
CH2_k127_6314029_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 385.0
CH2_k127_633821_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.727e-262 815.0
CH2_k127_633821_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.748e-235 734.0
CH2_k127_633821_2 PFAM Formaldehyde-activating enzyme (Fae) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 321.0
CH2_k127_633821_3 MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000001212 208.0
CH2_k127_633821_4 - - - - 0.00000000000000000000000000000005248 133.0
CH2_k127_633821_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000001296 98.0
CH2_k127_633821_6 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000001327 97.0
CH2_k127_633821_7 - - - - 0.0000000002832 64.0
CH2_k127_6368091_0 Belongs to the heat shock protein 70 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 461.0
CH2_k127_6368091_1 Domain of unknown function (DUF2760) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002199 270.0
CH2_k127_6368091_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000001683 174.0
CH2_k127_6368091_3 - - - - 0.000000000000000000000000196 110.0
CH2_k127_6408131_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1739.0
CH2_k127_6433858_0 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005926 287.0
CH2_k127_6433858_1 Glutaminase K01425 - 3.5.1.2 0.00000000000000000000000000000408 129.0
CH2_k127_6500659_0 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 392.0
CH2_k127_6500659_1 PemK-like, MazF-like toxin of type II toxin-antitoxin system K18841 - - 0.000000000000009821 74.0
CH2_k127_6500659_2 TonB dependent receptor K02014 - - 0.000000000005515 75.0
CH2_k127_6534446_0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 2.732e-231 720.0
CH2_k127_6534446_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347 - 1.6.5.8 2.116e-224 698.0
CH2_k127_6534446_2 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 - 1.6.5.8 7.36e-206 647.0
CH2_k127_6534446_3 Exonuclease C-terminal K01141 - 3.1.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 590.0
CH2_k127_6534446_4 TrkA-C domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 459.0
CH2_k127_6534446_5 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 446.0
CH2_k127_6534446_6 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 396.0
CH2_k127_6534446_7 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0055114 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 367.0
CH2_k127_6534446_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000005676 179.0
CH2_k127_6534446_9 (Na+)-NQR maturation NqrM K05952 - - 0.000000000000000181 81.0
CH2_k127_6608412_0 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 582.0
CH2_k127_6608412_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001343 265.0
CH2_k127_6632151_0 FAD linked oxidases, C-terminal domain K03777 - 1.1.5.12 5.886e-220 692.0
CH2_k127_6632151_1 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 548.0
CH2_k127_6632151_2 Periplasmic or secreted lipoprotein - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0044462,GO:0044464,GO:0071944 - 0.0000000004652 61.0
CH2_k127_6642054_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.0 1125.0
CH2_k127_6642054_1 50S ribosome-binding GTPase K06946 - - 1.324e-277 858.0
CH2_k127_6642054_2 50S ribosome-binding GTPase - - - 2.304e-224 698.0
CH2_k127_6642054_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 562.0
CH2_k127_6642054_4 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 378.0
CH2_k127_6642054_5 NlpC/P60 family K13695,K19303 - - 0.000000000000000000000000000000000000002499 154.0
CH2_k127_6642054_6 RNA-binding protein - - - 0.0000000000000000000000000000000006004 132.0
CH2_k127_6642054_7 COG1943 Transposase and inactivated derivatives K07491 - - 0.000000000000000000000000003725 113.0
CH2_k127_6642054_8 Transposase IS200 like K07491 - - 0.00000000000000000002579 91.0
CH2_k127_6642054_9 - - - - 0.00000000000006424 77.0
CH2_k127_6655569_0 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 475.0
CH2_k127_6655569_1 (ABC) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 469.0
CH2_k127_6655569_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 317.0
CH2_k127_6655569_3 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002706 276.0
CH2_k127_6655569_4 - - - - 0.000000000000000000000000000000000000000002105 157.0
CH2_k127_6655569_5 AAA domain K07133 - - 0.000000000000000000000000000000000003874 139.0
CH2_k127_6655569_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000147 121.0
CH2_k127_6659526_0 DNA RNA helicase - - - 0.0 1804.0
CH2_k127_6659526_1 Phosphate acyltransferases - - - 3.314e-253 799.0
CH2_k127_6659526_2 PFAM SWIM zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 469.0
CH2_k127_6659526_3 Helix-hairpin-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 461.0
CH2_k127_6659526_4 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 417.0
CH2_k127_6680201_0 phosphoglycolate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 328.0
CH2_k127_6680201_1 Peptidase S24-like K03503 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002227 249.0
CH2_k127_6680201_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000000000000006125 177.0
CH2_k127_6680201_3 SOS mutagenesis and repair protein UmuC K03502 - - 0.00000000001201 67.0
CH2_k127_6692565_0 Peptidase M50 K16922 - - 6.677e-229 729.0
CH2_k127_6692565_1 GAF domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 385.0
CH2_k127_6692565_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000555 263.0
CH2_k127_6696374_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 5.471e-220 698.0
CH2_k127_6696374_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 3.691e-219 685.0
CH2_k127_6696374_10 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000000000000005406 210.0
CH2_k127_6696374_11 YcxB-like protein - - - 0.00000000000000000000000000000000000000000000000000000005517 201.0
CH2_k127_6696374_12 Protein of unknown function (DUF2782) - - - 0.00000000000000000000000000000000008749 136.0
CH2_k127_6696374_13 Protein of unknown function (DUF721) - - - 0.0000000000000002008 85.0
CH2_k127_6696374_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 564.0
CH2_k127_6696374_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 522.0
CH2_k127_6696374_4 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 527.0
CH2_k127_6696374_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 469.0
CH2_k127_6696374_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 454.0
CH2_k127_6696374_7 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 449.0
CH2_k127_6696374_8 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 419.0
CH2_k127_6696374_9 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006388 411.0
CH2_k127_6730755_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 498.0
CH2_k127_6730755_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000005981 225.0
CH2_k127_6734162_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009928 267.0
CH2_k127_6734162_1 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.000000000000000000000000000000000000002824 149.0
CH2_k127_6734162_2 Phosphate-starvation-inducible E - - - 0.0000000000000000000000004469 108.0
CH2_k127_673724_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1780.0
CH2_k127_673724_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.365e-308 952.0
CH2_k127_673724_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 297.0
CH2_k127_673724_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008418 255.0
CH2_k127_673724_4 CRS1_YhbY K07574 - - 0.0000000000000000000000000005233 115.0
CH2_k127_6737635_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 7.191e-286 882.0
CH2_k127_6737635_1 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 386.0
CH2_k127_6737635_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 322.0
CH2_k127_6737635_3 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000000000000000001343 183.0
CH2_k127_6744230_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 3.123e-226 705.0
CH2_k127_6744230_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 552.0
CH2_k127_6744230_10 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000004855 100.0
CH2_k127_6744230_2 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 510.0
CH2_k127_6744230_3 PFAM NnrS K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 481.0
CH2_k127_6744230_4 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 377.0
CH2_k127_6744230_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 312.0
CH2_k127_6744230_6 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 306.0
CH2_k127_6744230_7 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 305.0
CH2_k127_6744230_8 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000002391 235.0
CH2_k127_6744230_9 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000003824 100.0
CH2_k127_6796263_0 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000005075 250.0
CH2_k127_6796263_1 Branched-chain amino acid ATP-binding cassette transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001164 241.0
CH2_k127_6796263_2 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.00000000000000000000000000000000000000000000000000007639 192.0
CH2_k127_6796263_3 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00007506 54.0
CH2_k127_6801202_0 Circularly permuted ATP-grasp type 2 - - - 4.536e-265 821.0
CH2_k127_6801202_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 388.0
CH2_k127_6931370_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 5.431e-201 636.0
CH2_k127_6931370_1 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000005432 90.0
CH2_k127_693155_0 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 409.0
CH2_k127_693155_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 408.0
CH2_k127_693155_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K19696 - 2.4.2.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 342.0
CH2_k127_693155_3 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001909 285.0
CH2_k127_693155_4 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002809 271.0
CH2_k127_693155_5 HIT domain - - - 0.00000000000000000000000000000000000000000000000000000000375 203.0
CH2_k127_693155_6 Dodecin K09165 - - 0.000000000000000000000000000001967 123.0
CH2_k127_693155_7 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0008150,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0042546,GO:0044085,GO:0071554,GO:0071840 3.2.1.52 0.00007439 46.0
CH2_k127_6958716_0 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 347.0
CH2_k127_6958716_1 gag-polyprotein putative aspartyl protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007486 255.0
CH2_k127_6958716_2 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000002274 97.0
CH2_k127_6974818_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008964,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.1.1.31 0.0 1395.0
CH2_k127_6974818_1 N-6 DNA methylase K03427 - 2.1.1.72 0.00000000000000000000000001026 109.0
CH2_k127_6984281_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 441.0
CH2_k127_6984281_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 334.0
CH2_k127_6986954_0 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 609.0
CH2_k127_6986954_1 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005216 265.0
CH2_k127_7011824_0 GTP-binding protein TypA K06207 - - 0.0 1049.0
CH2_k127_7011824_1 DNA helicase K03657 - 3.6.4.12 0.0 1048.0
CH2_k127_7011824_10 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 332.0
CH2_k127_7011824_11 epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 307.0
CH2_k127_7011824_12 Glycosyl transferase family 4 K13007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002431 276.0
CH2_k127_7011824_13 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K01769 - 4.6.1.1,4.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000361 275.0
CH2_k127_7011824_14 DNA methylase - - - 0.000000000000000000000000000000000000000000000000000000000000000006744 231.0
CH2_k127_7011824_15 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000001567 199.0
CH2_k127_7011824_16 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000003539 203.0
CH2_k127_7011824_17 PFAM FxsA cytoplasmic membrane protein K07113 - - 0.000000000000000000000000000000000000000000000000001279 187.0
CH2_k127_7011824_18 Belongs to the peptidase S16 family - - - 0.000000000000000000000000000000000000006802 147.0
CH2_k127_7011824_19 Divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000000000008257 144.0
CH2_k127_7011824_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0 1045.0
CH2_k127_7011824_20 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000001212 107.0
CH2_k127_7011824_21 Domain of Unknown Function with PDB structure (DUF3862) - - - 0.0000000000000000001776 91.0
CH2_k127_7011824_22 AIG2 family - - - 0.00000000002976 66.0
CH2_k127_7011824_3 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 1.019e-273 861.0
CH2_k127_7011824_4 Polysaccharide biosynthesis protein - - - 1.994e-266 832.0
CH2_k127_7011824_5 HTH transcriptional regulator, LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 440.0
CH2_k127_7011824_6 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 443.0
CH2_k127_7011824_7 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 410.0
CH2_k127_7011824_8 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 416.0
CH2_k127_7011824_9 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 369.0
CH2_k127_7024216_0 Belongs to the heat shock protein 70 family - - - 0.0 1309.0
CH2_k127_7024216_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.37e-254 788.0
CH2_k127_7024216_10 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000007756 91.0
CH2_k127_7024216_11 COG1943 Transposase and inactivated derivatives K07491 - - 0.0000000000003947 70.0
CH2_k127_7024216_12 Peptidoglycan-binding domain 1 protein - - - 0.0000000000007907 70.0
CH2_k127_7024216_13 - - - - 0.000000000003882 79.0
CH2_k127_7024216_14 PFAM Integrase catalytic - - - 0.00003149 46.0
CH2_k127_7024216_2 BT1 family - - - 2.22e-217 689.0
CH2_k127_7024216_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 580.0
CH2_k127_7024216_4 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 390.0
CH2_k127_7024216_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000004624 237.0
CH2_k127_7024216_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000008406 198.0
CH2_k127_7024216_7 Protein of unknown function (DUF3426) - - - 0.0000000000000000000000000000000000000000001609 166.0
CH2_k127_7024216_8 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000001104 156.0
CH2_k127_7024216_9 Protein required for attachment to host cells - - - 0.0000000000000000000000000000000000008232 143.0
CH2_k127_7025833_0 PFAM Radical SAM - - - 2.221e-203 640.0
CH2_k127_7025833_1 AsnC-type helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000006949 188.0
CH2_k127_7029801_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 2.032e-248 785.0
CH2_k127_7029801_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.101e-228 710.0
CH2_k127_7029801_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000002025 163.0
CH2_k127_7029801_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000001281 149.0
CH2_k127_7031182_0 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 348.0
CH2_k127_7031182_1 DDE_Tnp_1-associated - - - 0.000000000000000000000000000000000000000001893 162.0
CH2_k127_7031182_2 Cytochrome c - - - 0.00000000000000000000000000000006501 124.0
CH2_k127_7031182_3 transposase activity - - - 0.00000000000000000000000000000348 129.0
CH2_k127_7031379_0 Sulfate adenylyltransferase subunit 2 K00957 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004779,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0070566,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 585.0
CH2_k127_7031379_1 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 565.0
CH2_k127_7031379_2 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 322.0
CH2_k127_7031379_3 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000000000000000000001093 128.0
CH2_k127_7036483_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 579.0
CH2_k127_7036483_1 TIGRFAM SUF system FeS K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000703 263.0
CH2_k127_7036483_2 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001864 245.0
CH2_k127_7036483_3 Rieske 2Fe-2S K05710 - - 0.0000000000000000000000000000000000000000000000398 171.0
CH2_k127_7036483_4 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0005346 44.0
CH2_k127_7048645_0 CoA binding domain K09181 - - 0.0 1393.0
CH2_k127_7048645_1 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 514.0
CH2_k127_7048645_2 Phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 423.0
CH2_k127_7048645_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000004132 170.0
CH2_k127_7048645_4 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000005986 93.0
CH2_k127_7048645_5 Gram-negative-bacterium-type cell outer membrane assembly - - - 0.000000002116 66.0
CH2_k127_7088056_0 DNA RNA helicase - - - 0.0 1041.0
CH2_k127_7088056_1 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 501.0
CH2_k127_7088056_10 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000005073 175.0
CH2_k127_7088056_11 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000001042 155.0
CH2_k127_7088056_12 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000004173 132.0
CH2_k127_7088056_13 FAD linked oxidases, C-terminal domain K03777 - 1.1.5.12 0.00000000000000000000000000000002985 132.0
CH2_k127_7088056_14 Periplasmic or secreted lipoprotein - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0032153,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000004405 116.0
CH2_k127_7088056_2 LppC putative lipoprotein K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 449.0
CH2_k127_7088056_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 378.0
CH2_k127_7088056_4 isomerase K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 323.0
CH2_k127_7088056_5 Protein tyrosine kinase K08884,K11912 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000096 288.0
CH2_k127_7088056_6 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000003113 237.0
CH2_k127_7088056_7 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000008582 233.0
CH2_k127_7088056_8 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000001518 204.0
CH2_k127_7088056_9 Group 1 truncated hemoglobin K06886 - - 0.000000000000000000000000000000000000000000000000000000009375 199.0
CH2_k127_7132071_0 PFAM ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000008789 247.0
CH2_k127_7132071_1 PFAM SEC-C motif K09858 - - 0.0000000000000000000000000000000000000000000000000008748 189.0
CH2_k127_7132071_2 Hydantoinase/oxoprolinase - - - 0.00000000000000000000000000000000001974 140.0
CH2_k127_7132071_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000003615 70.0
CH2_k127_7132722_0 Peptidase, M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 445.0
CH2_k127_7132722_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 425.0
CH2_k127_7132722_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007233 272.0
CH2_k127_7132722_3 Peptidase, M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000003336 182.0
CH2_k127_7132722_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000009167 145.0
CH2_k127_7156937_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 7.618e-229 715.0
CH2_k127_7156937_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 559.0
CH2_k127_7156937_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009546 349.0
CH2_k127_7156937_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001111 260.0
CH2_k127_7156937_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000000002668 174.0
CH2_k127_7179476_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1514.0
CH2_k127_7179476_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 524.0
CH2_k127_7179476_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K14067 - 6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000007895 226.0
CH2_k127_7179476_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000002412 194.0
CH2_k127_7248084_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1508.0
CH2_k127_7257894_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1263.0
CH2_k127_7257894_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 0.0 1176.0
CH2_k127_7257894_10 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 521.0
CH2_k127_7257894_11 PFAM DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 458.0
CH2_k127_7257894_12 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 449.0
CH2_k127_7257894_13 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 436.0
CH2_k127_7257894_14 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 427.0
CH2_k127_7257894_15 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 422.0
CH2_k127_7257894_16 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006276,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0010332,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042221,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0046677,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 426.0
CH2_k127_7257894_17 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 412.0
CH2_k127_7257894_18 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 402.0
CH2_k127_7257894_19 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 341.0
CH2_k127_7257894_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding K01652 - 2.2.1.6 0.0 1026.0
CH2_k127_7257894_20 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 323.0
CH2_k127_7257894_21 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 295.0
CH2_k127_7257894_22 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 291.0
CH2_k127_7257894_23 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004064 276.0
CH2_k127_7257894_24 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001241 269.0
CH2_k127_7257894_25 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000005975 264.0
CH2_k127_7257894_26 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000000000000000000000001332 212.0
CH2_k127_7257894_27 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000000006612 187.0
CH2_k127_7257894_28 Transposase IS200 like K07491 - - 0.000000000000000000000000000000388 125.0
CH2_k127_7257894_29 - - - - 0.00000000000000000000000005918 111.0
CH2_k127_7257894_3 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor region - - - 1.088e-312 972.0
CH2_k127_7257894_30 - - - - 0.0000004037 55.0
CH2_k127_7257894_4 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K01507,K15987 - 3.6.1.1 8.422e-291 908.0
CH2_k127_7257894_5 Response regulator receiver - - - 2.629e-221 692.0
CH2_k127_7257894_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 8.489e-196 626.0
CH2_k127_7257894_7 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 593.0
CH2_k127_7257894_8 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 584.0
CH2_k127_7257894_9 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 572.0
CH2_k127_7258267_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1962.0
CH2_k127_7258267_1 Glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 1.527e-291 902.0
CH2_k127_7258267_2 - - - - 0.000000000000000000000000006602 113.0
CH2_k127_7258267_3 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000003204 91.0
CH2_k127_7270773_0 TIGRFAM ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter - - - 0.0 1213.0
CH2_k127_7270773_1 Belongs to the peptidase S16 family - - - 0.0 1074.0
CH2_k127_7270773_2 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 598.0
CH2_k127_7270773_3 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 338.0
CH2_k127_7270773_4 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 336.0
CH2_k127_7270773_5 IgGFc binding protein - - - 0.0000000000000000000000000000000000000000000002884 192.0
CH2_k127_7270773_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000004072 158.0
CH2_k127_7283544_0 Protein of unknown function (DUF3375) - - - 3.782e-250 778.0
CH2_k127_7283544_1 Thiol disulfide interchange protein K02199 - - 0.00000000000000000000000000000000000000000000000000000003199 202.0
CH2_k127_7283544_2 Domain of unknown function (DUF4194) - - - 0.0000000000000000000000000000000000000000000000001232 181.0
CH2_k127_7283544_3 TIGRFAM Cytochrome c-type biogenesis protein CcmI K02200 - - 0.00000000000000000000000000000000000000000000005385 185.0
CH2_k127_7283544_4 subunit of a heme lyase K02200 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - 0.00000000000000000000000000000000000003793 156.0
CH2_k127_7283544_5 Cytochrome c-type biogenesis protein K02198 - - 0.000000005406 57.0
CH2_k127_7283544_6 protein homotetramerization - - - 0.00003922 47.0
CH2_k127_728749_0 PFAM Bacterial extracellular solute-binding - - - 2.317e-309 964.0
CH2_k127_728749_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 1.038e-208 655.0
CH2_k127_728749_2 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 471.0
CH2_k127_728749_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 434.0
CH2_k127_728749_4 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 314.0
CH2_k127_728749_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000009258 241.0
CH2_k127_728749_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000001088 145.0
CH2_k127_728749_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000001959 136.0
CH2_k127_728749_8 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000003047 87.0
CH2_k127_7290077_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1029.0
CH2_k127_7290077_1 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 411.0
CH2_k127_7290077_2 PFAM Radical SAM K19810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 370.0
CH2_k127_7290077_3 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008644 342.0
CH2_k127_7312563_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.095e-229 715.0
CH2_k127_7312563_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 370.0
CH2_k127_7312563_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 356.0
CH2_k127_7312563_3 PFAM Cystathionine beta-synthase, core K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000003114 229.0
CH2_k127_7312563_4 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000001158 205.0
CH2_k127_7312563_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000009948 190.0
CH2_k127_7312563_6 - - - - 0.0000005201 52.0
CH2_k127_7324606_0 Histidine Phosphotransfer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 441.0
CH2_k127_7349221_0 Adenylosuccinate lyase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 514.0
CH2_k127_7349221_1 Argininosuccinate lyase C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 492.0
CH2_k127_7349221_2 Coenzyme A transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 456.0
CH2_k127_7349221_3 phosphosulfolactate synthase activity K08097 - 4.4.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 417.0
CH2_k127_7349221_4 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 404.0
CH2_k127_7349221_5 (2R)-phospho-3-sulfolactate synthase (ComA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 342.0
CH2_k127_7349221_6 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 315.0
CH2_k127_7349221_7 PFAM short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004444 256.0
CH2_k127_7363327_0 S1, RNA binding domain K06959 - - 0.0 1124.0
CH2_k127_7363327_1 TIGRFAM Nitrate transport ATP-binding K15578 - - 0.0 999.0
CH2_k127_7363327_10 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 308.0
CH2_k127_7363327_11 MlaC protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003071 269.0
CH2_k127_7363327_12 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007092 272.0
CH2_k127_7363327_13 Belongs to the Fur family K09823 - - 0.00000000000000000000000000000000000000000000000000000000000000008332 226.0
CH2_k127_7363327_14 PFAM response regulator receiver K07183 - - 0.0000000000000000000000000000000000000000000000000000000002544 208.0
CH2_k127_7363327_15 Domain of unknown function DUF29 - - - 0.000000000000000000000000000000000000000000000000000000003409 202.0
CH2_k127_7363327_16 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000000000002349 192.0
CH2_k127_7363327_17 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000000000000000000000003026 185.0
CH2_k127_7363327_18 - - - - 0.0000000000000000000000000000000000000000001345 160.0
CH2_k127_7363327_19 Cupin domain K11312 - - 0.00000000000000000000000000000000228 134.0
CH2_k127_7363327_2 P-loop containing region of AAA domain K03546 - - 5.292e-255 826.0
CH2_k127_7363327_20 Peptidase C39 family K06992 - - 0.00000000000000000000000000000001327 141.0
CH2_k127_7363327_21 - - - - 0.0000000000000000000000000000000502 130.0
CH2_k127_7363327_22 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000004172 127.0
CH2_k127_7363327_23 - - - - 0.000000000000000000000041 105.0
CH2_k127_7363327_24 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000001296 98.0
CH2_k127_7363327_25 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000002829 97.0
CH2_k127_7363327_27 Alginate export - - - 0.0000000000003898 74.0
CH2_k127_7363327_28 BNR repeat-like domain K01186 - 3.2.1.18 0.00001655 49.0
CH2_k127_7363327_3 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 2.07e-238 753.0
CH2_k127_7363327_4 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576 - - 7.854e-237 738.0
CH2_k127_7363327_5 PFAM Binding-protein-dependent transport systems inner membrane component K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 564.0
CH2_k127_7363327_6 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008946 515.0
CH2_k127_7363327_7 NMT1-like family K15576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 467.0
CH2_k127_7363327_8 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 396.0
CH2_k127_7363327_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 390.0
CH2_k127_7370289_0 PFAM ATP-grasp fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 582.0
CH2_k127_7370289_1 TIGRFAM dihydroxyacetone kinase, DhaK subunit K05878 - 2.7.1.121 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 550.0
CH2_k127_7370289_2 Belongs to the HAD-like hydrolase superfamily K01101 - 3.1.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 407.0
CH2_k127_7370289_3 Ion channel - - - 0.000000000000000000000000000003459 125.0
CH2_k127_7370289_4 TIGRFAM Dihydroxyacetone kinase K05879 - 2.7.1.121 0.00000000000000003935 82.0
CH2_k127_7381680_0 argininosuccinate lyase K01755 - 4.3.2.1 6.247e-225 706.0
CH2_k127_7381680_1 TIGRFAM dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009875 585.0
CH2_k127_7381680_10 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000000000000000000000009881 218.0
CH2_k127_7381680_11 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000002987 106.0
CH2_k127_7381680_12 Regulator of RNA polymerase sigma(70) subunit, Rsd/AlgQ - - - 0.000000000000008306 76.0
CH2_k127_7381680_13 Selenoprotein, putative - - - 0.00000000000002414 75.0
CH2_k127_7381680_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 520.0
CH2_k127_7381680_3 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 522.0
CH2_k127_7381680_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 445.0
CH2_k127_7381680_5 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 424.0
CH2_k127_7381680_6 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 376.0
CH2_k127_7381680_7 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000947 272.0
CH2_k127_7381680_8 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007113 261.0
CH2_k127_7381680_9 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000002224 230.0
CH2_k127_7385016_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 466.0
CH2_k127_7385016_1 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003983 277.0
CH2_k127_7385016_2 FecR protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007539 268.0
CH2_k127_7385016_3 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000003724 160.0
CH2_k127_7385016_4 PFAM Restriction endonuclease, type I, EcoRI, R subunit Type III, Res subunit, N-terminal K01153 - 3.1.21.3 0.0000000000000002669 82.0
CH2_k127_7385016_5 PFAM Restriction endonuclease, type I, EcoRI, R subunit Type III, Res subunit, N-terminal K01153 - 3.1.21.3 0.00000000000001263 77.0
CH2_k127_7385016_6 PFAM Restriction endonuclease, type I, EcoRI, R subunit Type III, Res subunit, N-terminal K01153 - 3.1.21.3 0.0000000001507 66.0
CH2_k127_7385016_7 PFAM restriction modification system DNA specificity domain K01154 - 3.1.21.3 0.0002299 47.0
CH2_k127_7399206_0 Glycogen debranching enzyme - - - 0.0 1245.0
CH2_k127_7399206_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1214.0
CH2_k127_7399206_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.018e-291 910.0
CH2_k127_7399206_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009394 430.0
CH2_k127_7399206_4 Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 340.0
CH2_k127_7399206_5 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.000000000000000000000000000000005154 128.0
CH2_k127_7414532_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.929e-269 833.0
CH2_k127_7414532_1 Multicopper oxidase - - - 3.064e-224 707.0
CH2_k127_7414532_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000005594 63.0
CH2_k127_7438303_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1124.0
CH2_k127_7438303_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 322.0
CH2_k127_7438303_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000000000002457 117.0
CH2_k127_7438303_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031004,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.0000000000000000003437 88.0
CH2_k127_7469048_0 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 478.0
CH2_k127_7469048_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 370.0
CH2_k127_7469048_2 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 340.0
CH2_k127_7469048_3 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001869 274.0
CH2_k127_7469048_4 DsrE/DsrF-like family K07235 - - 0.00000000000000000000000000000000000000000000000000009347 188.0
CH2_k127_7469048_5 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000000000000008374 145.0
CH2_k127_7469048_6 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000000000000004035 132.0
CH2_k127_7469048_7 Belongs to the DsrF TusC family K07236 - - 0.00000000000000000000007866 103.0
CH2_k127_7469048_8 - - - - 0.0000004941 56.0
CH2_k127_7488911_0 homoserine dehydrogenase K00003 - 1.1.1.3 6.428e-230 718.0
CH2_k127_7488911_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 549.0
CH2_k127_7488911_2 Domain of unknown function (DUF4160) - - - 0.0000000000000000000000000000000000000000009474 156.0
CH2_k127_7488911_3 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000000000009291 128.0
CH2_k127_7488911_4 - - - - 0.000000000000000000001432 98.0
CH2_k127_7488911_5 - - - - 0.0000005258 52.0
CH2_k127_7526027_0 Bacterial DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1676.0
CH2_k127_7526027_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.836e-218 688.0
CH2_k127_7526027_2 Type II secretory pathway, component - - - 0.00000000000001047 83.0
CH2_k127_7532207_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 506.0
CH2_k127_7532207_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 395.0
CH2_k127_7553621_0 Phage terminase large subunit (GpA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 541.0
CH2_k127_7553621_1 - - - - 0.000000000000000000000000000000000002493 143.0
CH2_k127_7609_0 Belongs to the CarA family K01956 - 6.3.5.5 1.472e-197 621.0
CH2_k127_7609_1 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 355.0
CH2_k127_7609_2 Transglycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 335.0
CH2_k127_7609_3 Aspartyl protease - - - 0.0000000000000000000000000002541 118.0
CH2_k127_7610216_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 4.997e-251 781.0
CH2_k127_7610216_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.02e-221 692.0
CH2_k127_7610216_10 Cytochrome C1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 332.0
CH2_k127_7610216_11 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 328.0
CH2_k127_7610216_12 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 322.0
CH2_k127_7610216_13 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005397 250.0
CH2_k127_7610216_14 Putative DNA-binding domain K09929 - - 0.0000000000000000000000000000000000000000000000000000000000000000002787 241.0
CH2_k127_7610216_15 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000006408 228.0
CH2_k127_7610216_16 PFAM Stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000000000000000001353 194.0
CH2_k127_7610216_17 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000002526 152.0
CH2_k127_7610216_18 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.0000000000000000000000000000000007045 135.0
CH2_k127_7610216_19 Domain of unknown function (DUF1820) - - - 0.000000000000000000000000000000009087 129.0
CH2_k127_7610216_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 4.39e-204 642.0
CH2_k127_7610216_20 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000001037 116.0
CH2_k127_7610216_21 STAS domain K07122 - - 0.000000000000000000000005449 105.0
CH2_k127_7610216_22 Winged helix-turn-helix domain (DUF2582) - - - 0.00000000000000000001932 92.0
CH2_k127_7610216_23 PFAM Smr - - - 0.0000002462 52.0
CH2_k127_7610216_3 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 526.0
CH2_k127_7610216_4 Belongs to the ParA family K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 480.0
CH2_k127_7610216_5 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 446.0
CH2_k127_7610216_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009404 449.0
CH2_k127_7610216_7 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 419.0
CH2_k127_7610216_8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 345.0
CH2_k127_7610216_9 PFAM Glutathione S-transferase, N-terminal K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 334.0
CH2_k127_764028_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K17686 - 3.6.3.54 0.0 1053.0
CH2_k127_764028_1 Heavy-metal-associated domain K07213 - - 0.000000000000002566 77.0
CH2_k127_7762393_0 Belongs to the heat shock protein 70 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 604.0
CH2_k127_7762393_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 384.0
CH2_k127_7762393_2 PFAM CreA K05805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009398 245.0
CH2_k127_7762393_3 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000001834 241.0
CH2_k127_7762393_4 - - - - 0.000000000000000000000000000000000000000005868 157.0
CH2_k127_7825432_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 534.0
CH2_k127_7825432_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 530.0
CH2_k127_7825432_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 492.0
CH2_k127_7825432_3 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 347.0
CH2_k127_7825432_4 DsrE/DsrF-like family K07235 - - 0.0000000004453 61.0
CH2_k127_786707_0 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 559.0
CH2_k127_786707_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 481.0
CH2_k127_786707_2 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 367.0
CH2_k127_786707_3 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000002647 212.0
CH2_k127_7883875_0 Oxaloacetate decarboxylase, alpha subunit K01571 - 4.1.1.3 6.002e-268 838.0
CH2_k127_7883875_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 8.837e-211 664.0
CH2_k127_7883875_2 decarboxylase, beta subunit K01572 - 4.1.1.3 1.523e-197 623.0
CH2_k127_7883875_3 Histidine kinase K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 564.0
CH2_k127_7883875_4 AI-2E family transporter K03548 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 451.0
CH2_k127_7883875_5 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 460.0
CH2_k127_7883875_6 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001904 278.0
CH2_k127_7883875_7 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000268 272.0
CH2_k127_7883875_8 Lyase and sodium transporter K01573 - 4.1.1.3 0.000001164 53.0
CH2_k127_7915027_0 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 337.0
CH2_k127_7915027_1 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000000000002004 216.0
CH2_k127_7915027_2 Competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000002597 154.0
CH2_k127_7970073_0 kinase domain - - - 1.128e-195 621.0
CH2_k127_7970073_1 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 365.0
CH2_k127_7970073_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000007298 210.0
CH2_k127_7970073_3 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000549 138.0
CH2_k127_7970073_5 Belongs to the 'phage' integrase family - - - 0.00000002709 57.0
CH2_k127_7970073_6 Transposase zinc-ribbon domain - - - 0.00009202 45.0
CH2_k127_7975470_0 UPF0313 protein - - - 0.0 1160.0
CH2_k127_7975470_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.4.2 2.739e-273 846.0
CH2_k127_7975470_2 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 GO:0003674,GO:0003824,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016154,GO:0016740,GO:0016757,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000004855 141.0
CH2_k127_8010294_0 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000003326 246.0
CH2_k127_8010294_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000008924 216.0
CH2_k127_8010294_2 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000006209 208.0
CH2_k127_8029121_0 DNA helicase K03654 - 3.6.4.12 8.727e-195 614.0
CH2_k127_8029121_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 442.0
CH2_k127_8029121_2 PIN domain - - - 0.000000000000000000000000000000000000000293 153.0
CH2_k127_8029121_3 nucleic acid-binding protein contains PIN domain - - - 0.00000000000000000000000000000000000002067 147.0
CH2_k127_8029121_4 Type I restriction-modification system K03427 - 2.1.1.72 0.000000000000000000000000000002139 121.0
CH2_k127_8029121_5 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000000000000005135 99.0
CH2_k127_8029121_6 - - - - 0.00000000000000000000005336 100.0
CH2_k127_8058519_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 561.0
CH2_k127_8058519_1 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 372.0
CH2_k127_8058519_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000003395 153.0
CH2_k127_8058519_3 - - - - 0.0000000000000000000000000000000000006332 141.0
CH2_k127_8058519_4 Protein of unknown function (DUF433) - - - 0.0000000000000000000000000005141 114.0
CH2_k127_8140531_0 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 427.0
CH2_k127_8140531_1 MlaD protein K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 353.0
CH2_k127_8140531_2 ABC-type transport auxiliary lipoprotein component K09857 - - 0.000000000000000000000000000000000000000000000001045 181.0
CH2_k127_8140531_3 Permease MlaE K02066 - - 0.0000000000000000000000002397 106.0
CH2_k127_8152601_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 2454.0
CH2_k127_8164142_0 Glutamyl glutaminyl-tRNA synthetase, class Ic, anti-codon binding domain K01886 - 6.1.1.18 4.945e-292 902.0
CH2_k127_8164142_1 Protein of unknown function (DUF1097) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000253 250.0
CH2_k127_8164142_2 Domain of unknown function (DUF4389) - - - 0.0000005779 55.0
CH2_k127_8198626_0 Mechanosensitive ion channel K05802 - - 7.095e-313 992.0
CH2_k127_8198626_1 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 442.0
CH2_k127_8198626_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0008534,GO:0009987,GO:0016787,GO:0016788,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 343.0
CH2_k127_8198626_3 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 325.0
CH2_k127_8198626_4 High frequency lysogenization protein HflD homolog K07153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 284.0
CH2_k127_8198626_5 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005542 265.0
CH2_k127_8203872_0 PFAM Binding-protein-dependent transport systems inner membrane component K02037 - - 7.504e-314 977.0
CH2_k127_8203872_1 Phosphate transport system permease protein K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004826 516.0
CH2_k127_8203872_2 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 500.0
CH2_k127_8214801_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 3.522e-224 713.0
CH2_k127_8214801_1 C-terminal domain of 1-Cys peroxiredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 394.0
CH2_k127_8214801_2 - - - - 0.000000000000000000000000000000000000000000001974 171.0
CH2_k127_8214801_3 Ferredoxin - - - 0.0000000000004242 69.0
CH2_k127_8231658_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 436.0
CH2_k127_8231658_1 Phosphate transport system permease protein K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 356.0
CH2_k127_8231658_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 312.0
CH2_k127_8231658_3 Lipase maturation factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001495 272.0
CH2_k127_8231658_4 - - - - 0.000000000000000000000000000000000000001893 150.0
CH2_k127_8231658_5 Glycine-zipper domain - - - 0.000000000000000000007812 94.0
CH2_k127_8231658_6 Protein of unknown function (DUF1254) - - - 0.00005972 45.0
CH2_k127_8278159_0 4Fe-4S dicluster domain K16965,K17051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 551.0
CH2_k127_8278159_1 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 362.0
CH2_k127_8278159_2 Nitrate reductase K00373 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001132 261.0
CH2_k127_8278159_3 Alginate export - - - 0.000000000002674 72.0
CH2_k127_828186_0 Belongs to the alpha-IPM synthase homocitrate synthase family K09011 - 2.3.1.182 5.874e-291 899.0
CH2_k127_828186_1 PFAM Stage II sporulation protein E (SpoIIE) - - - 9.472e-255 800.0
CH2_k127_828186_2 PAAR repeat-containing protein - - - 0.0000000000000000000000000000001272 138.0
CH2_k127_828186_3 Family membership K08884,K12132 - 2.7.11.1 0.000000000000000000000327 99.0
CH2_k127_8397935_0 May be involved in recombinational repair of damaged DNA K03631 - - 1.11e-200 636.0
CH2_k127_8397935_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 430.0
CH2_k127_8464090_0 Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 330.0
CH2_k127_8464090_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000002419 212.0
CH2_k127_8464090_2 PFAM Small Multidrug Resistance protein K11741 - - 0.00000000000000000000000000000000000000000007855 161.0
CH2_k127_8464090_3 Part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000001725 144.0
CH2_k127_8464090_4 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000004432 136.0
CH2_k127_8466247_0 efflux pump - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 301.0
CH2_k127_8466247_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004103 289.0
CH2_k127_8466247_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.0000000000000000000000000000000000006916 143.0
CH2_k127_8466247_3 Fuseless - - - 0.000000000000000000000000000001836 122.0
CH2_k127_8505637_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 557.0
CH2_k127_8505637_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 534.0
CH2_k127_8505637_2 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 367.0
CH2_k127_8505637_3 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002976 281.0
CH2_k127_8505637_4 Competence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004933 274.0
CH2_k127_8505637_5 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 GO:0003674,GO:0003824,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197 0.000000000000000000000005111 106.0
CH2_k127_8509565_0 Putative exonuclease SbcCD, C subunit - - - 0.0 1293.0
CH2_k127_8509565_1 Domain of unknown function (DUF4194) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 295.0
CH2_k127_8551957_0 PFAM Isocitrate isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 490.0
CH2_k127_8551957_1 alcohol dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 452.0
CH2_k127_8551957_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 334.0
CH2_k127_8551957_3 Thioredoxin K07396 - - 0.0000000000000000000000000000000000000000000000000000001474 201.0
CH2_k127_8551957_4 - - - - 0.0000000000004617 76.0
CH2_k127_85847_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 3.278e-202 643.0
CH2_k127_8619593_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 9.964e-195 612.0
CH2_k127_8619593_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 396.0
CH2_k127_8619593_2 - - - - 0.000000000000000000008221 93.0
CH2_k127_8644230_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 589.0
CH2_k127_8644230_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 418.0
CH2_k127_8644230_2 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 340.0
CH2_k127_8644230_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000001879 264.0
CH2_k127_8644230_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000001004 222.0
CH2_k127_8666845_0 TonB dependent receptor K16092 - - 5.049e-225 713.0
CH2_k127_8668666_0 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 318.0
CH2_k127_8668666_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 289.0
CH2_k127_8668666_2 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000002032 219.0
CH2_k127_8668666_3 ABC transporter transmembrane region K06147,K18893 - - 0.0000000000000000000000000000000131 127.0
CH2_k127_8668666_4 Polynucleotide adenylyltransferase K00974 - 2.7.7.72 0.0000000000000000000000000001177 121.0
CH2_k127_8672394_0 AcrB/AcrD/AcrF family K15726 - - 1.231e-272 860.0
CH2_k127_8672394_2 - - - - 0.0000639 48.0
CH2_k127_8711835_0 Carbohydrate phosphorylase - - - 0.0 1206.0
CH2_k127_8711835_1 alcohol dehydrogenase K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 585.0
CH2_k127_8711835_2 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 568.0
CH2_k127_8711835_3 Peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 355.0
CH2_k127_877524_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 610.0
CH2_k127_877524_1 PFAM Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 554.0
CH2_k127_877524_10 Domain of unknown function (DUF4124) - - - 0.00004392 51.0
CH2_k127_877524_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 452.0
CH2_k127_877524_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008809 396.0
CH2_k127_877524_4 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 359.0
CH2_k127_877524_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009553 297.0
CH2_k127_877524_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000001051 228.0
CH2_k127_877524_7 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 0.00000000000000000000000000000000000000000000000000000003629 202.0
CH2_k127_877524_8 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000001679 90.0
CH2_k127_877524_9 Protein of unknown function (DUF2934) - - - 0.000000000006074 68.0
CH2_k127_8834924_0 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016787,GO:0016810,GO:0016814,GO:0018759,GO:0019238,GO:0043446,GO:0044237,GO:0071704 3.5.4.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 505.0
CH2_k127_8834924_1 GHMP kinases N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 444.0
CH2_k127_8834924_2 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001936 282.0
CH2_k127_8834924_3 Haloacid dehalogenase-like hydrolase - - - 0.000000000004961 69.0
CH2_k127_8857370_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 608.0
CH2_k127_8857370_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 572.0
CH2_k127_8857370_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 516.0
CH2_k127_8857370_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0000287,GO:0003674,GO:0003824,GO:0004349,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019202,GO:0019752,GO:0031406,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0055129,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901973 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 469.0
CH2_k127_8857370_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000000004151 173.0
CH2_k127_8857370_5 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000000000000000000000000009322 148.0
CH2_k127_8857370_6 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000002085 139.0
CH2_k127_8857370_7 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000000000002566 125.0
CH2_k127_8863387_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 326.0
CH2_k127_8863387_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002989 265.0
CH2_k127_8892271_0 Major Facilitator Superfamily - - - 7.958e-272 841.0
CH2_k127_8892271_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 6.969e-215 672.0
CH2_k127_8892271_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 398.0
CH2_k127_8892271_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 367.0
CH2_k127_8892271_4 PFAM N-acetylmuramoyl-L-alanine amidase K03806 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002912 271.0
CH2_k127_8892271_5 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006879 254.0
CH2_k127_8892271_6 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000001297 219.0
CH2_k127_8892271_7 Iron-sulfur cluster insertion protein ErpA K15724 - - 0.000000000000000000000000000000000000000000000000000000000002165 209.0
CH2_k127_8908826_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000000000000000000000000000000000000000000000000000000000000002246 229.0
CH2_k127_8908826_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000003321 222.0
CH2_k127_8908826_2 - - - - 0.000000000000000000000000000000000000000003576 158.0
CH2_k127_8970023_0 Paraquat-inducible protein B - - - 6.893e-197 644.0
CH2_k127_8970023_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 592.0
CH2_k127_8970023_2 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 292.0
CH2_k127_8970023_3 paraquat-inducible protein A K03808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000007491 219.0
CH2_k127_8970023_4 Paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000004897 170.0
CH2_k127_8970023_5 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000003704 134.0
CH2_k127_8970023_6 Sulfatase - - - 0.000000000000000000000000000002059 123.0
CH2_k127_8998925_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 458.0
CH2_k127_8998925_1 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 371.0
CH2_k127_8998925_2 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000006053 118.0
CH2_k127_8998925_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000001499 111.0
CH2_k127_9033907_0 Phosphate transporter K03306 - - 2.215e-198 622.0
CH2_k127_9033907_1 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 455.0
CH2_k127_9033907_2 Mut7-C ubiquitin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 369.0
CH2_k127_9033907_3 Pit accessory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 338.0
CH2_k127_9033907_4 TIGRFAM formylmethanofuran dehydrogenase subunit C K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000008193 173.0
CH2_k127_9033907_5 - - - - 0.00000000000000000000000000000000000000000000001077 176.0
CH2_k127_9033907_6 DNA replication, synthesis of RNA primer K04066 - - 0.00000000000000000002333 96.0
CH2_k127_9033907_7 - - - - 0.00000000000000002791 82.0
CH2_k127_907574_0 - - - - 1.533e-250 800.0
CH2_k127_907574_1 Signal transduction response regulator, receiver - - - 0.00000000000000000000000000001438 126.0
CH2_k127_9097039_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.002e-245 771.0
CH2_k127_9097039_1 ATP synthase alpha/beta family, beta-barrel domain K02118 - - 1.419e-237 739.0
CH2_k127_9097039_10 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.00000002354 62.0
CH2_k127_9097039_2 Sulfate permease and related transporters (MFS superfamily) - - - 3.156e-224 707.0
CH2_k127_9097039_3 V-type ATPase 116kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 557.0
CH2_k127_9097039_4 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 437.0
CH2_k127_9097039_5 Sodium/hydrogen exchanger family K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007029 267.0
CH2_k127_9097039_6 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000001939 232.0
CH2_k127_9097039_7 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000001223 209.0
CH2_k127_9097039_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000000000000000000000000000000000002964 210.0
CH2_k127_9097039_9 Protein of unknown function (DUF2764) - - - 0.0000000000000000000000000000000000000000000005448 174.0
CH2_k127_9100125_0 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 476.0
CH2_k127_9100125_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 452.0
CH2_k127_9100125_2 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 363.0
CH2_k127_9100125_3 PFAM Type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 350.0
CH2_k127_9100125_4 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000000002911 114.0
CH2_k127_9199313_0 Circularly permuted ATP-grasp type 2 - - - 0.0 1075.0
CH2_k127_9199313_1 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 361.0
CH2_k127_9199313_2 Bacterial transglutaminase-like N-terminal - - - 0.000000000000000000000000000000000000000000000003225 174.0
CH2_k127_9208467_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.043e-217 688.0
CH2_k127_9208467_1 HsdM N-terminal domain K03427 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 318.0
CH2_k127_9208467_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 301.0
CH2_k127_9208467_3 ATP synthase K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000006084 243.0
CH2_k127_9208467_4 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000003368 199.0
CH2_k127_9208467_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000005871 135.0
CH2_k127_9229007_0 TIGRFAM ATP-binding cassette protein, ChvD family - - - 1.538e-314 966.0
CH2_k127_9229007_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 406.0
CH2_k127_9229007_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 300.0
CH2_k127_9229505_0 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 543.0
CH2_k127_9229505_1 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000712 256.0
CH2_k127_9229505_2 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000007308 139.0
CH2_k127_9229505_3 ISXO2-like transposase domain - - - 0.0000003597 53.0
CH2_k127_9229505_4 HNH nucleases - - - 0.00007105 46.0
CH2_k127_9263888_0 PFAM 5'-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008216 452.0
CH2_k127_9263888_1 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 444.0
CH2_k127_9263888_2 PFAM Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000393 245.0
CH2_k127_9263888_3 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000001757 185.0
CH2_k127_9263888_4 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000001966 129.0
CH2_k127_9263888_5 - - - - 0.0000000000000000000000000000004656 128.0
CH2_k127_9263888_6 MEKHLA domain - - - 0.000000000000000000000000000002864 127.0
CH2_k127_9291190_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 471.0
CH2_k127_9291190_1 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 434.0
CH2_k127_9291190_2 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 374.0
CH2_k127_9291190_3 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 301.0
CH2_k127_9291190_4 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000133 171.0
CH2_k127_9295140_0 Alginate export - - - 7.232e-252 784.0
CH2_k127_9295140_1 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 4.056e-222 701.0
CH2_k127_9295140_10 domain protein - - - 0.000000000000000008292 85.0
CH2_k127_9295140_11 PFAM Integrase core domain - - - 0.00000000002801 67.0
CH2_k127_9295140_12 Small protein - - - 0.0000001749 55.0
CH2_k127_9295140_13 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000003765 60.0
CH2_k127_9295140_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 567.0
CH2_k127_9295140_3 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 561.0
CH2_k127_9295140_4 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 496.0
CH2_k127_9295140_5 PFAM Bacterial extracellular solute-binding K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 494.0
CH2_k127_9295140_6 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 454.0
CH2_k127_9295140_7 Bacterial regulatory helix-turn-helix protein, lysR family K13634 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 346.0
CH2_k127_9295140_8 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001974 269.0
CH2_k127_9295140_9 ABC transporter permease protein K02047 - - 0.000000000000000000002404 94.0
CH2_k127_9409342_0 PFAM Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 494.0
CH2_k127_9409342_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 466.0
CH2_k127_9409342_2 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 464.0
CH2_k127_9409342_3 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000000000000000000000000005528 228.0
CH2_k127_9409342_4 Protein of unknown function (DUF502) - - - 0.00000189 50.0
CH2_k127_9446516_0 P-type ATPase K17686 - 3.6.3.54 5.389e-310 972.0
CH2_k127_9446516_1 Transglycosylase - - - 6.533e-257 813.0
CH2_k127_9446516_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000003735 192.0
CH2_k127_9446516_11 - - - - 0.000000000000000000000000000000000000000000000000974 184.0
CH2_k127_9446516_12 - - - - 0.000000000000000000000000000000001807 134.0
CH2_k127_9446516_13 - - - - 0.000000000000000006745 89.0
CH2_k127_9446516_14 - - - - 0.0000000000000005485 78.0
CH2_k127_9446516_15 - - - - 0.0000000001753 64.0
CH2_k127_9446516_2 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 568.0
CH2_k127_9446516_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 541.0
CH2_k127_9446516_4 TIGRFAM PQQ-dependent catabolism-associated beta-propeller protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 479.0
CH2_k127_9446516_5 TIGRFAM ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 452.0
CH2_k127_9446516_6 TIGRFAM alcohol ABC transporter, permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 441.0
CH2_k127_9446516_7 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 377.0
CH2_k127_9446516_8 TIGRFAM ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 341.0
CH2_k127_9446516_9 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001303 249.0
CH2_k127_9473982_0 PFAM Aminoacyl-tRNA synthetase, class II (G H P S), conserved region K01892 - 6.1.1.21 9.172e-201 632.0
CH2_k127_9473982_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 557.0
CH2_k127_9473982_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 464.0
CH2_k127_9473982_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 442.0
CH2_k127_9473982_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000008023 241.0
CH2_k127_9473982_5 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001 242.0
CH2_k127_9473982_6 Pilus biogenesis K02656 - - 0.000000000000000000000000000000000000000000000000000002 200.0
CH2_k127_9532120_0 Carbon starvation protein CstA K06200 - - 5.68e-209 653.0
CH2_k127_9532120_1 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 315.0
CH2_k127_9532120_2 Cellulase (glycosyl hydrolase family 5) K01210 - 3.2.1.58 0.0000000000000000006938 87.0
CH2_k127_977389_0 FAD binding domain K09828 - 1.3.1.72 5.197e-230 723.0
CH2_k127_977389_1 COG0480 Translation elongation factors (GTPases) K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 560.0
CH2_k127_977389_2 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000008558 118.0
CH2_k127_977389_3 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000008124 85.0
CH2_k127_977389_4 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000003555 75.0
CH2_k127_980363_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 4.281e-293 903.0
CH2_k127_980363_1 Sulfatase - - - 1.925e-219 689.0
CH2_k127_980381_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 2.767e-212 664.0
CH2_k127_980381_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000004417 165.0
CH2_k127_9835473_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1018.0
CH2_k127_9835473_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.67e-291 902.0
CH2_k127_9835473_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 6.681e-286 893.0
CH2_k127_9835473_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 7.219e-228 712.0
CH2_k127_9835473_4 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 0.00000000000000000000000000000000000000000000000000000000003193 211.0
CH2_k127_9835473_5 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000003378 201.0
CH2_k127_9835473_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000006532 114.0
CH2_k127_9836879_0 Mg chelatase-related protein K07391 - - 6.978e-253 787.0
CH2_k127_9836879_1 TIGRFAM Pilus retraction protein PilT K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009373 390.0
CH2_k127_9836879_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 314.0
CH2_k127_9836879_3 Membrane fusogenic activity K09806 - - 0.0000000000000000000000000002444 116.0
CH2_k127_9869595_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 3.056e-256 796.0
CH2_k127_9869595_1 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 358.0
CH2_k127_9869595_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 365.0
CH2_k127_9869595_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 338.0
CH2_k127_9869595_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 320.0
CH2_k127_9869595_5 Aconitase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 305.0
CH2_k127_9869595_6 AcrB/AcrD/AcrF family K15726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001985 278.0
CH2_k127_9869595_7 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003023 245.0
CH2_k127_9869595_8 (ABC) transporter K02471,K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000009355 231.0
CH2_k127_9869595_9 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.000000000000007215 88.0
CH2_k127_9878339_0 PFAM multicopper oxidase type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 358.0
CH2_k127_9878339_1 - - - - 0.0000000000000000000000000000000000000000000000003157 180.0
CH2_k127_9878339_2 Membrane - - - 0.00000000000000000000000000000000000000000000002013 174.0
CH2_k127_9878339_3 - - - - 0.000000000000000000000000000001308 121.0
CH2_k127_990980_0 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 358.0
CH2_k127_990980_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 323.0
CH2_k127_990980_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000004415 219.0
CH2_k127_990980_3 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000004311 205.0
CH2_k127_990980_4 Belongs to the UPF0434 family K09791 - - 0.00000000000000162 76.0
CH2_k127_990980_5 - - - - 0.0000000000002844 74.0
CH2_k127_9956949_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 605.0
CH2_k127_9956949_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 311.0
CH2_k127_9956949_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000000000001109 214.0
CH2_k127_9956949_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000177 203.0