logo

Overview

ID MAG00253
Name CH2_bin.47
Sample SMP0008
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanomicrobia
Order Methanomicrobiales
Family Methanospirillaceae
Genus UBA9949
Species
Assembly information
Completeness (%) 51.02
Contamination (%) 0.19
GC content (%) 53.0
N50 (bp) 5,707
Genome size (bp) 706,923

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes820

Gene name Description KEGG GOs EC E-value Score Sequence
CH2_k127_10002363_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 404.0
CH2_k127_10002363_1 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 374.0
CH2_k127_10002363_2 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 284.0
CH2_k127_10002363_3 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000001923 163.0
CH2_k127_10002363_4 beta-lactamase domain protein - - - 0.0000000000007462 70.0
CH2_k127_10057586_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 4.329e-207 649.0
CH2_k127_10057586_1 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004045 276.0
CH2_k127_10057586_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001664 276.0
CH2_k127_10057586_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000001716 237.0
CH2_k127_10057586_4 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.000000000000000000000000000000000000000000000000000000009235 199.0
CH2_k127_10057586_5 - - - - 0.000000000000000000000000000000000000000001231 164.0
CH2_k127_10057586_6 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.00000000000000000000000000000000002887 134.0
CH2_k127_10057586_7 Binds to the 23S rRNA K02896 - - 0.000000000000000000000000000009457 119.0
CH2_k127_10057586_8 Tetratricopeptide repeat - - - 0.00000000003281 69.0
CH2_k127_10103499_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 2.022e-247 772.0
CH2_k127_10103499_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 346.0
CH2_k127_10103499_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 284.0
CH2_k127_10103499_3 PIN domain of ribonuclease K07060 - - 0.0000000000000000000000000000000000000000000000921 173.0
CH2_k127_10103499_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000005692 135.0
CH2_k127_10103499_5 Sulfur transfer protein involved in thiamine biosynthesis K03154,K21947 GO:0003674,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0031386,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070647,GO:0071704,GO:1901564 2.8.1.15 0.00007814 47.0
CH2_k127_10157903_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1310.0
CH2_k127_10157903_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001331 282.0
CH2_k127_10157903_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000003561 218.0
CH2_k127_10157903_3 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.0000000000000000000000000000000000000000000000000000000000001058 214.0
CH2_k127_10157903_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000001941 215.0
CH2_k127_10157903_5 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000003858 190.0
CH2_k127_10186273_0 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 455.0
CH2_k127_10186273_1 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000004472 199.0
CH2_k127_10186273_2 regulatory, ligand-binding protein related to C-terminal domains of K channels K07228 - - 0.000000000000000000000000000000000000000000000000005746 184.0
CH2_k127_10186273_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000005231 154.0
CH2_k127_10186273_4 PFAM Yip1 domain - - - 0.0000000000000000000000000001493 121.0
CH2_k127_10186273_5 Alternative locus ID - - - 0.00000000000000000000000005582 119.0
CH2_k127_10186273_6 - - - - 0.0000000000001701 75.0
CH2_k127_10358210_0 acid binding OB-fold tRNA helicase-type K07463 - - 3.359e-312 970.0
CH2_k127_10358210_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.44e-246 764.0
CH2_k127_10358210_10 PFAM Yip1 domain - - - 0.00000000000000000003213 98.0
CH2_k127_10358210_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 444.0
CH2_k127_10358210_3 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 367.0
CH2_k127_10358210_4 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 325.0
CH2_k127_10358210_5 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000001606 246.0
CH2_k127_10358210_6 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000659 219.0
CH2_k127_10358210_7 adenyl ribonucleotide binding - - - 0.00000000000000000000000000000000000000000000005206 175.0
CH2_k127_10358210_8 - - - - 0.00000000000000000000000000000000005217 134.0
CH2_k127_10358210_9 - - - - 0.0000000000000000000003779 100.0
CH2_k127_1038485_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.0 1115.0
CH2_k127_1038485_1 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 447.0
CH2_k127_1038485_2 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 372.0
CH2_k127_1038485_3 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 326.0
CH2_k127_1038485_4 PFAM formate nitrite transporter K21993 - - 0.000000000000000000000000000000000000001516 147.0
CH2_k127_10419285_0 ATP-grasp domain K06913 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006461 421.0
CH2_k127_10419285_1 Methanogenesis marker protein 8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 317.0
CH2_k127_10419285_10 - - - - 0.0000000000000000000000004275 108.0
CH2_k127_10419285_2 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000248 277.0
CH2_k127_10419285_3 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001669 271.0
CH2_k127_10419285_4 Belongs to the UPF0280 family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001661 255.0
CH2_k127_10419285_5 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005188 242.0
CH2_k127_10419285_6 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.00000000000000000000000000000000000000000000000000000000000000000734 228.0
CH2_k127_10419285_7 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000004848 157.0
CH2_k127_10419285_8 - - - - 0.0000000000000000000000000000000003866 142.0
CH2_k127_10419285_9 - - - - 0.0000000000000000000000000007448 117.0
CH2_k127_10442579_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1459.0
CH2_k127_10442579_1 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 536.0
CH2_k127_10442579_2 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 302.0
CH2_k127_10556305_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 6.232e-252 781.0
CH2_k127_10556305_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.96e-248 777.0
CH2_k127_10556305_2 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 426.0
CH2_k127_10556305_3 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000005606 88.0
CH2_k127_10767403_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 525.0
CH2_k127_10767403_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 507.0
CH2_k127_10767403_2 serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 338.0
CH2_k127_10767403_3 KH domain protein K06961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002119 265.0
CH2_k127_10767403_4 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000003029 156.0
CH2_k127_10871330_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 574.0
CH2_k127_10871330_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009092 466.0
CH2_k127_10871330_2 PFAM PUA domain containing protein K07575 - - 0.00000000000000000000000000000000000000000000000000000000000000003238 226.0
CH2_k127_10871330_3 ZPR1-related zinc finger protein K06874 - - 0.000000000000000000000000000000000000000000000000000000000000435 215.0
CH2_k127_10871330_4 Pfam:DUF552 K09152 - - 0.00000000000000000000000000000000000000000000000000000345 192.0
CH2_k127_10871330_5 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.000000000000000000000008355 102.0
CH2_k127_10877585_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 1.065e-207 649.0
CH2_k127_10877585_1 CoB--CoM heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 520.0
CH2_k127_10877585_2 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008989 518.0
CH2_k127_10877585_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 492.0
CH2_k127_10877585_4 Domain of unknown function (DUF1743) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 419.0
CH2_k127_10877585_5 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 359.0
CH2_k127_10877585_6 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 333.0
CH2_k127_10877585_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 323.0
CH2_k127_10877585_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11260 - - 0.000000000000000000000000000000000000001978 148.0
CH2_k127_10990149_0 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 593.0
CH2_k127_10990149_1 Protein of unknown function (DUF475) K09799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 465.0
CH2_k127_10990149_2 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000009793 213.0
CH2_k127_10990149_3 PFAM Desulfoferrodoxin ferrous iron-binding region K05919 - 1.15.1.2 0.000000000000000000000000000000000001618 140.0
CH2_k127_10990149_4 COG0607 Rhodanese-related sulfurtransferase K03151 - 2.8.1.4 0.0000000000000000000002121 100.0
CH2_k127_10990149_5 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000001808 70.0
CH2_k127_11053903_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 1.183e-297 920.0
CH2_k127_11053903_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 2.466e-257 799.0
CH2_k127_11053903_10 WD-40 repeat protein - - - 0.0000000000000000000000000000000000000000000005143 191.0
CH2_k127_11053903_11 - - - - 0.000000000000000000000000000002906 121.0
CH2_k127_11053903_12 PFAM Uncharacterised protein family Ycf35 - - - 0.000000000000000001358 90.0
CH2_k127_11053903_2 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 2.044e-240 746.0
CH2_k127_11053903_3 ATPase family associated with various cellular activities (AAA) - - - 5.133e-235 737.0
CH2_k127_11053903_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.124e-197 622.0
CH2_k127_11053903_5 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 391.0
CH2_k127_11053903_6 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 296.0
CH2_k127_11053903_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01657,K02500 GO:0000107,GO:0003674,GO:0003824,GO:0008150,GO:0016740,GO:0016757,GO:0016763,GO:0040007 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 291.0
CH2_k127_11053903_8 unfolded protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000001178 245.0
CH2_k127_11053903_9 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04068 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000009919 196.0
CH2_k127_11056661_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1410.0
CH2_k127_11056661_1 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001164 278.0
CH2_k127_11056661_2 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004637 233.0
CH2_k127_11056661_3 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000004384 201.0
CH2_k127_11056661_4 zinc finger, SWIM - - - 0.00000000000000000000000000000002469 129.0
CH2_k127_11056661_5 - - - - 0.000000000000000000000001133 110.0
CH2_k127_1123151_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0 1018.0
CH2_k127_1123151_1 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 601.0
CH2_k127_1123151_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 473.0
CH2_k127_1123151_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000009427 243.0
CH2_k127_1123151_4 - - - - 0.0000000000000000000000000000000000000000001175 164.0
CH2_k127_1123151_5 H subunit K02107 - - 0.00000000000000000000000000000405 123.0
CH2_k127_11264875_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 3.115e-204 638.0
CH2_k127_11264875_1 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 353.0
CH2_k127_11264875_2 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 306.0
CH2_k127_11264875_3 PFAM ribosomal protein S8E K02995 - - 0.0000000000000000000000000000000000000000000000000000001609 196.0
CH2_k127_11264875_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.00000000000000000000000000558 112.0
CH2_k127_11264875_5 RNA-binding protein involved in rRNA processing K07569 - - 0.0000000000000000000253 93.0
CH2_k127_11302904_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.363e-266 829.0
CH2_k127_11302904_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 590.0
CH2_k127_11302904_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 501.0
CH2_k127_11302904_3 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 379.0
CH2_k127_11302904_4 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 335.0
CH2_k127_11302904_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008148 255.0
CH2_k127_11302904_6 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000004818 156.0
CH2_k127_11302904_7 - - - - 0.00000000000000000000000009562 108.0
CH2_k127_11302904_8 PFAM metallophosphoesterase - - - 0.000000001553 68.0
CH2_k127_11676453_0 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 412.0
CH2_k127_11676453_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 381.0
CH2_k127_11676453_2 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 339.0
CH2_k127_11676453_3 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000000000000000000001074 212.0
CH2_k127_11676453_4 transcription termination protein NusA K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000002483 199.0
CH2_k127_11676453_5 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000004171 164.0
CH2_k127_11676453_6 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000744 127.0
CH2_k127_11676453_7 Ferrous iron transport B domain protein K04759 - - 0.000000000000000000000000000499 115.0
CH2_k127_11676453_8 Protein of unknown function (DUF357) K09728 - - 0.000000000000000000000000003644 117.0
CH2_k127_11748105_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 2.818e-255 797.0
CH2_k127_11748105_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 - 1.3.4.1 5.865e-235 734.0
CH2_k127_11748105_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 521.0
CH2_k127_11748105_3 N-4 methylation of cytosine K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 505.0
CH2_k127_11748105_4 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000902 216.0
CH2_k127_11748105_5 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000000000000000000000087 164.0
CH2_k127_11748105_6 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000001578 105.0
CH2_k127_11748105_7 Belongs to the UPF0758 family K03630 - - 0.000000000001299 70.0
CH2_k127_11771642_0 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 566.0
CH2_k127_11771642_1 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 568.0
CH2_k127_11771642_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 559.0
CH2_k127_11771642_3 Mediates influx of magnesium ions K03284 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 334.0
CH2_k127_11771642_4 COG1361 S-layer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 310.0
CH2_k127_11771642_5 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001743 262.0
CH2_k127_11771642_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000002758 239.0
CH2_k127_11771642_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000002547 190.0
CH2_k127_11771642_8 Yip1 domain - - - 0.0000000000000000000000000000000000000000000001784 176.0
CH2_k127_11802228_0 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001953 285.0
CH2_k127_11802228_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000318 275.0
CH2_k127_11802228_2 PFAM nucleoside recognition domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001476 276.0
CH2_k127_11802228_3 PFAM NAD(P)H dehydrogenase (quinone) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000279 271.0
CH2_k127_11802228_4 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000000000000000000248 169.0
CH2_k127_11802228_5 Transcriptional regulator K07729 - - 0.00000000000000000000000007349 109.0
CH2_k127_11802228_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000001566 106.0
CH2_k127_11802228_7 - - - - 0.000000000000000000006195 97.0
CH2_k127_11802228_8 - - - - 0.000000000000004004 83.0
CH2_k127_11874582_0 Heat shock 70 kDa protein K04043 - - 8.887e-315 972.0
CH2_k127_11874582_1 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 569.0
CH2_k127_11874582_10 COG1881 Phospholipid-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000001266 201.0
CH2_k127_11874582_11 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000004655 173.0
CH2_k127_11874582_12 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000002589 159.0
CH2_k127_11874582_13 Ribonuclease K03469 - 3.1.26.4 0.000000000000000000000000000000000514 135.0
CH2_k127_11874582_14 - - - - 0.000000000000000000000000007313 112.0
CH2_k127_11874582_15 Peptidase dimerisation domain - - - 0.0000000000000000001539 92.0
CH2_k127_11874582_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 527.0
CH2_k127_11874582_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007075 463.0
CH2_k127_11874582_4 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 368.0
CH2_k127_11874582_5 RNA methylase K07446 - 2.1.1.213 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 363.0
CH2_k127_11874582_6 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 344.0
CH2_k127_11874582_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 338.0
CH2_k127_11874582_8 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000001066 244.0
CH2_k127_11874582_9 Functions by promoting the formation of the first peptide bond K03263 - - 0.00000000000000000000000000000000000000000000000000000000000006828 214.0
CH2_k127_12095174_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 2.576e-229 717.0
CH2_k127_12095174_1 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 494.0
CH2_k127_12095174_2 PFAM ABC transporter K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000001559 242.0
CH2_k127_12095174_3 PFAM ABC transporter K16786 - - 0.0000000000000000000000000000000000000000000000000000000006948 209.0
CH2_k127_12095174_4 PFAM BioY protein K03523 - - 0.00000000000000000000000000000000000000000000000000001804 194.0
CH2_k127_12106195_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1324.0
CH2_k127_12106195_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1139.0
CH2_k127_12106195_2 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 418.0
CH2_k127_12106195_3 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 357.0
CH2_k127_12106195_4 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 289.0
CH2_k127_12106195_5 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000002937 188.0
CH2_k127_12106195_6 Belongs to the UPF0147 family K09721 - - 0.0000000000000000000000000000000000000000008215 157.0
CH2_k127_12106195_7 - - - - 0.000000000000000000000000000000000000000568 150.0
CH2_k127_12106195_8 PDGLE domain K02009 - - 0.0000000000000000000000000000000001373 136.0
CH2_k127_12106195_9 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.000000005867 56.0
CH2_k127_12447039_0 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 4.574e-256 797.0
CH2_k127_12447039_1 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 418.0
CH2_k127_12447039_2 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 285.0
CH2_k127_12447039_3 ribosomal protein S15 K02956 - - 0.000000000000000000000000000000000000000000000000000000000000000000004858 236.0
CH2_k127_12447039_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000002545 174.0
CH2_k127_12447039_5 - - - - 0.0000000000000007332 81.0
CH2_k127_12447039_6 Radical SAM domain protein - - - 0.00000000000001421 74.0
CH2_k127_12505394_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 9.005e-217 691.0
CH2_k127_12505394_1 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000000000000000000000000000000000000000000000001053 215.0
CH2_k127_12505394_2 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000005051 192.0
CH2_k127_12505394_3 DNA polymerase activity K02319 - 2.7.7.7 0.000000000000000000000000000000009135 135.0
CH2_k127_12505394_5 - - - - 0.000000000003251 68.0
CH2_k127_12505394_6 - - - - 0.0000006494 56.0
CH2_k127_12543999_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0 1034.0
CH2_k127_12543999_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 5.55e-274 846.0
CH2_k127_12543999_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 327.0
CH2_k127_12543999_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000004626 133.0
CH2_k127_12543999_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000001377 128.0
CH2_k127_12543999_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000003314 96.0
CH2_k127_12586570_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 578.0
CH2_k127_12586570_1 FHA domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 289.0
CH2_k127_12586570_2 PFAM NADH ubiquinone oxidoreductase, 20 K14088 - - 0.000000000000000000000000000000000000000000000000000000002262 201.0
CH2_k127_12586570_3 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K14089 - - 0.0000000000000000000000000000000000000000001329 162.0
CH2_k127_12586570_4 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) K14091,K15831 - - 0.0000000000000000000000000000000000000000002966 162.0
CH2_k127_12586570_5 Endonuclease V K05982 - 3.1.21.7 0.00000000000000000000000000000000000000004673 160.0
CH2_k127_12586570_6 cell adhesion involved in biofilm formation - - - 0.00000000000002034 84.0
CH2_k127_12665385_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.828e-213 676.0
CH2_k127_12665385_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 355.0
CH2_k127_12665385_2 Belongs to the SUI1 family K03113 - - 0.0000000000000000000000000000000000000000000000000000005014 194.0
CH2_k127_12665385_3 Zn-ribbon containing protein K07163 - - 0.000000000000001587 78.0
CH2_k127_12769863_0 PFAM Thiolase K00626 - 2.3.1.9 5.143e-211 661.0
CH2_k127_12769863_1 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 591.0
CH2_k127_12769863_10 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000004104 180.0
CH2_k127_12769863_11 Ferredoxin K05337 - - 0.00000000000000002917 83.0
CH2_k127_12769863_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 585.0
CH2_k127_12769863_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 348.0
CH2_k127_12769863_4 Methyltransferase K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 351.0
CH2_k127_12769863_5 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 304.0
CH2_k127_12769863_6 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 299.0
CH2_k127_12769863_7 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 284.0
CH2_k127_12769863_8 Helix-turn-helix domain protein K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000003367 241.0
CH2_k127_12769863_9 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000000000000000009049 217.0
CH2_k127_12788874_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 411.0
CH2_k127_12788874_1 Thiamine-phosphate synthase K21220 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000001324 224.0
CH2_k127_12788874_2 structural constituent of ribosome K02962 - - 0.00000000000000000001667 92.0
CH2_k127_12788874_3 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000001614 62.0
CH2_k127_12788874_4 - - - - 0.00002399 50.0
CH2_k127_12812692_0 PFAM Radical SAM domain protein K06937 - - 6.899e-247 768.0
CH2_k127_12812692_1 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 603.0
CH2_k127_12812692_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 499.0
CH2_k127_12812692_3 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 427.0
CH2_k127_12812692_4 RimK domain protein ATP-grasp K05844,K15740 - 6.3.2.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 347.0
CH2_k127_12812692_5 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.00000000000000000000000000000000000000000000000000000000000406 213.0
CH2_k127_12812692_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000957 179.0
CH2_k127_12812692_7 Uncharacterised protein family UPF0058 - - - 0.0000000000000000000000000000000000000000481 153.0
CH2_k127_12888460_0 phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 535.0
CH2_k127_12888460_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 427.0
CH2_k127_12888460_2 Belongs to the UPF0285 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 406.0
CH2_k127_12888460_3 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 286.0
CH2_k127_12888460_4 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 282.0
CH2_k127_12888460_5 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000000000000000006891 152.0
CH2_k127_12888460_6 Putative small multi-drug export protein - - - 0.0000000000000000000000000000001463 128.0
CH2_k127_12888460_7 helicase activity K06915 - - 0.0000000000000000000000000009907 120.0
CH2_k127_12888460_8 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000001377 103.0
CH2_k127_12914447_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 517.0
CH2_k127_12914447_1 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 387.0
CH2_k127_12914447_2 Belongs to the group II decarboxylase family. MfnA subfamily K18933 - 4.1.1.11,4.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 360.0
CH2_k127_12914447_3 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000008315 237.0
CH2_k127_12926804_0 DEAD DEAH box helicase domain protein K03724 - - 0.0 1269.0
CH2_k127_12926804_1 amine dehydrogenase activity K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 437.0
CH2_k127_12926804_2 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 316.0
CH2_k127_12926804_3 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 297.0
CH2_k127_12926804_4 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006648 271.0
CH2_k127_12926804_5 protein conserved in archaea K09746 - - 0.000000000000000000000000000002194 130.0
CH2_k127_12984416_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 8.018e-293 909.0
CH2_k127_12984416_1 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 4.282e-197 625.0
CH2_k127_12984416_2 PFAM Aldehyde dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 572.0
CH2_k127_13037989_0 PFAM ATPase, BadF BadG BcrA BcrD type - - - 5.344e-220 687.0
CH2_k127_13037989_1 methanogenesis marker protein 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 488.0
CH2_k127_13037989_2 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002725 233.0
CH2_k127_13037989_3 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.0000000000000000000000000000002629 123.0
CH2_k127_13037989_4 - - - - 0.000001607 55.0
CH2_k127_1344064_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 9.912e-214 668.0
CH2_k127_1344064_1 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 512.0
CH2_k127_1344064_10 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.000000000000000000000009275 103.0
CH2_k127_1344064_2 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 439.0
CH2_k127_1344064_3 PFAM Histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 368.0
CH2_k127_1344064_4 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 323.0
CH2_k127_1344064_5 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003451 254.0
CH2_k127_1344064_6 Belongs to the UPF0218 family K09735 - - 0.000000000000000000000000000000000000000000000000000003068 195.0
CH2_k127_1344064_7 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000000000000006029 115.0
CH2_k127_1344064_8 Large family of predicted nucleotide-binding domains K07158 - - 0.00000000000000000000000002619 115.0
CH2_k127_1344064_9 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000000000000001097 105.0
CH2_k127_1375654_0 TIGRFAM TraB family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006583 511.0
CH2_k127_1375654_1 Belongs to the UPF0284 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 394.0
CH2_k127_1375654_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001535 263.0
CH2_k127_1375654_3 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000001014 172.0
CH2_k127_1375654_4 PFAM metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000297 182.0
CH2_k127_1375654_5 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000006978 165.0
CH2_k127_1613270_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 537.0
CH2_k127_1613270_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 315.0
CH2_k127_1613270_2 Domain of unknown function (DUF1917) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 298.0
CH2_k127_1613270_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000001381 227.0
CH2_k127_1613270_4 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000000000001682 94.0
CH2_k127_1885818_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 2.649e-245 767.0
CH2_k127_1885818_1 Archaeal Nre, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 457.0
CH2_k127_1885818_2 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 324.0
CH2_k127_2119431_0 PFAM Aminotransferase class I and II K10907 - - 3.273e-196 618.0
CH2_k127_2119431_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 556.0
CH2_k127_2119431_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000003881 219.0
CH2_k127_2119431_3 PFAM regulatory protein AsnC Lrp family - - - 0.000000000000000000000000000000001541 130.0
CH2_k127_2119431_4 Trm112p-like protein - - - 0.0000000000000000001545 90.0
CH2_k127_2254076_0 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 539.0
CH2_k127_2254076_1 PFAM Cation K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 525.0
CH2_k127_2254076_2 uridine kinase K00855,K00876 - 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 289.0
CH2_k127_2254076_3 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000000000007215 204.0
CH2_k127_2263377_0 domain, Protein K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 559.0
CH2_k127_2263377_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 323.0
CH2_k127_2263377_2 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000003136 145.0
CH2_k127_2287413_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 3.968e-256 798.0
CH2_k127_2287413_1 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 362.0
CH2_k127_2287413_2 Protein of unknown function (DUF473) K09135 - - 0.00000000000000000000000000000000000000000001665 164.0
CH2_k127_2287413_3 - - - - 0.0000000000000000000000000000000007236 132.0
CH2_k127_2479716_0 Methyltransferase K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000001055 259.0
CH2_k127_2479716_1 - - - - 0.00000000000000000000004137 106.0
CH2_k127_2479716_2 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000009769 101.0
CH2_k127_2479716_3 permease - - - 0.0000000000000000002863 99.0
CH2_k127_2479716_4 small multi-drug export - - - 0.0000000000000000002881 94.0
CH2_k127_2479716_5 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.00007233 49.0
CH2_k127_2507457_0 PFAM PilT protein domain protein K06865 - - 6.778e-231 721.0
CH2_k127_2507457_1 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.000000000000000000000000000000000000000000000000000000000000000000000000001417 262.0
CH2_k127_2507457_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000005718 192.0
CH2_k127_2507457_3 - - - - 0.00000000000000000000000000000000000007571 149.0
CH2_k127_278658_0 Protein of unknown function (DUF460) K09150 - - 1.811e-239 752.0
CH2_k127_278658_1 PFAM TrkA-N domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 516.0
CH2_k127_278658_2 COG1361 S-layer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 422.0
CH2_k127_278658_3 PFAM PP-loop domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 387.0
CH2_k127_278658_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 349.0
CH2_k127_278658_5 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000003504 263.0
CH2_k127_278658_6 RIO-like serine threonine protein kinase fused to N-terminal HTH domain K07179 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000002329 227.0
CH2_k127_278658_7 PFAM transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000000000000000000000004676 216.0
CH2_k127_3036529_0 TIGRFAM UbiD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 593.0
CH2_k127_3036529_1 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 540.0
CH2_k127_3036529_2 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 486.0
CH2_k127_3036529_3 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 382.0
CH2_k127_3036529_4 - - - - 0.000000000000000000000000000000000001129 143.0
CH2_k127_3036529_5 Protein of unknown function DUF86 K07075 - - 0.000000000000000000000000006171 118.0
CH2_k127_3036529_6 metallopeptidase activity - - - 0.00000000005178 70.0
CH2_k127_3080968_0 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 589.0
CH2_k127_3080968_1 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 482.0
CH2_k127_3080968_2 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 450.0
CH2_k127_3080968_3 UDP-glucose:hexose-1-phosphate uridylyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 372.0
CH2_k127_3080968_4 Involved in cell shape control K22222 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 321.0
CH2_k127_3080968_5 PFAM sigma-70 region 4 domain protein K09714 - - 0.00000000000000000000000000000000000000000000000000000000000001519 217.0
CH2_k127_3080968_6 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000002093 173.0
CH2_k127_3173313_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 1.703e-303 942.0
CH2_k127_3173313_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005158 255.0
CH2_k127_3173313_2 Protein of unknown function (DUF432) K09149 - - 0.000000000000000000000000000000000000000000000000000001472 199.0
CH2_k127_3173313_3 PBS lyase K22221 - - 0.0000000000000000000000000000000000000000000000000002215 202.0
CH2_k127_3173313_4 - - - - 0.0000000000000000000000000000000000000003772 155.0
CH2_k127_3184619_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 537.0
CH2_k127_3184619_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008248 474.0
CH2_k127_3184619_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002809 282.0
CH2_k127_3184619_3 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain K07585 - - 0.000000000000000000000000000000000000000000000000000000000000000013 230.0
CH2_k127_3184619_4 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000000000000000000000000000000000005518 194.0
CH2_k127_3184619_5 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000000000000000000000000000000000000000025 171.0
CH2_k127_3184619_6 Belongs to the PDCD5 family K06875 - - 0.000000000000000000000000000000000000001509 150.0
CH2_k127_3184619_7 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.0000000000000000000000000000000000005764 140.0
CH2_k127_3184619_8 PFAM Ribosomal LX protein K02944 - - 0.0000000000000000000002388 97.0
CH2_k127_3184619_9 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000001125 86.0
CH2_k127_3227457_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 553.0
CH2_k127_3227457_1 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14101 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 370.0
CH2_k127_3227457_10 Predicted membrane protein (DUF2108) K14095 - - 0.000000000003819 71.0
CH2_k127_3227457_11 - K14100 - - 0.00001815 49.0
CH2_k127_3227457_12 - - - - 0.00002197 50.0
CH2_k127_3227457_2 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaH K14099 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001681 274.0
CH2_k127_3227457_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009982 256.0
CH2_k127_3227457_4 Predicted membrane protein (DUF2105) K14098 - - 0.00000000000000000000000000000000000000000000000000000000006258 210.0
CH2_k127_3227457_5 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaF K14097 - - 0.0000000000000000000000000000000000000000000000000003788 189.0
CH2_k127_3227457_6 - K14093 - - 0.00000000000000000000000000006273 116.0
CH2_k127_3227457_7 Predicted membrane protein (DUF2109) K14094 - - 0.00000000000000000000000001935 113.0
CH2_k127_3227457_8 PFAM NiFe -hydrogenase-3-type complex Eha, EhaM K14104 - - 0.0000000000000000000003502 101.0
CH2_k127_3227457_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K14107 - - 0.00000000000002322 74.0
CH2_k127_3367722_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 595.0
CH2_k127_3367722_1 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 573.0
CH2_k127_3367722_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 496.0
CH2_k127_3367722_3 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 408.0
CH2_k127_3367722_4 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.000000000000000000000000000000000000000000000000000003489 192.0
CH2_k127_3400686_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 484.0
CH2_k127_3400686_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009845 358.0
CH2_k127_3400686_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000003482 78.0
CH2_k127_3400686_11 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000006792 48.0
CH2_k127_3400686_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 336.0
CH2_k127_3400686_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 287.0
CH2_k127_3400686_4 Located on the platform of the 30S subunit K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001976 239.0
CH2_k127_3400686_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000006232 224.0
CH2_k127_3400686_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000002993 216.0
CH2_k127_3400686_7 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000009864 216.0
CH2_k127_3400686_8 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.00000000000000000000000000000000000000000000000000886 182.0
CH2_k127_3400686_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000000000000000000002641 127.0
CH2_k127_3442465_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 428.0
CH2_k127_3442465_1 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 376.0
CH2_k127_3442465_2 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004785 278.0
CH2_k127_3442465_3 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000028 250.0
CH2_k127_3442465_4 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007,K02009 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0072511,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000003461 139.0
CH2_k127_3442465_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000001016 119.0
CH2_k127_3442465_6 chorismate mutase K04093 - 5.4.99.5 0.00000000000000000000000009389 110.0
CH2_k127_3534231_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 8.7e-201 633.0
CH2_k127_3534231_1 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 444.0
CH2_k127_3534231_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 407.0
CH2_k127_3534231_3 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 383.0
CH2_k127_3534231_4 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 319.0
CH2_k127_3534231_5 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000000000000000000006466 235.0
CH2_k127_3534231_6 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000001682 232.0
CH2_k127_3534231_7 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000003677 220.0
CH2_k127_3534231_8 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000002706 198.0
CH2_k127_3534231_9 Tetratricopeptide repeat - - - 0.0000000006164 68.0
CH2_k127_370648_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 407.0
CH2_k127_370648_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 335.0
CH2_k127_370648_2 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 331.0
CH2_k127_370648_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000209 275.0
CH2_k127_370648_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.000000000000000000000000000000000000000000000000000000000000000000006129 239.0
CH2_k127_370648_5 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.0000000000000000000000000000000000000000000000001119 179.0
CH2_k127_370648_6 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000000000000000000000003619 173.0
CH2_k127_3888676_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 2.952e-262 820.0
CH2_k127_3888676_1 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009226 370.0
CH2_k127_3888676_2 Predicted membrane protein (DUF2070) K08979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005931 275.0
CH2_k127_3888676_3 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000183 240.0
CH2_k127_3888676_4 Belongs to the UPF0212 family K09731 - - 0.000000000000000000000000000000000000000000000000000001449 193.0
CH2_k127_3888676_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000004052 144.0
CH2_k127_3888676_6 Family of unknown function (DUF5350) - - - 0.0000000000000000000000003741 108.0
CH2_k127_3888676_7 - - - - 0.0000000000000000000001867 100.0
CH2_k127_4103878_0 PFAM Methyltransferase type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 460.0
CH2_k127_4103878_1 peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 452.0
CH2_k127_4103878_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 428.0
CH2_k127_4103878_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000764 259.0
CH2_k127_4103878_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004684 233.0
CH2_k127_4103878_5 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.000000000000000000000000000000000000000000000000000009945 192.0
CH2_k127_4393568_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1317.0
CH2_k127_4393568_1 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 437.0
CH2_k127_4393568_2 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 283.0
CH2_k127_4393568_3 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001041 274.0
CH2_k127_4393568_4 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000002377 194.0
CH2_k127_4393568_5 PFAM thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000005578 167.0
CH2_k127_4417045_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 561.0
CH2_k127_4417045_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 400.0
CH2_k127_4417045_2 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 322.0
CH2_k127_4417045_3 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000135 216.0
CH2_k127_4417045_4 - - - - 0.00000000000000000000000000000000000000000000000000000005591 199.0
CH2_k127_4557982_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 6.299e-263 813.0
CH2_k127_4557982_1 PFAM Aldehyde dehydrogenase K00130,K00135 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8 9.226e-201 636.0
CH2_k127_4557982_2 Anion transporter K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 580.0
CH2_k127_4557982_3 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 389.0
CH2_k127_4557982_4 Radical SAM ThiC family K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000001314 239.0
CH2_k127_4557982_5 RibD C-terminal domain K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000006998 205.0
CH2_k127_4557982_6 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000001051 163.0
CH2_k127_4557982_7 Psort location Cytoplasmic, score - - - 0.0000000000000000000000009693 118.0
CH2_k127_4605248_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 572.0
CH2_k127_4605248_1 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000001279 250.0
CH2_k127_4605248_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000003943 167.0
CH2_k127_4605248_3 Belongs to the TrpF family K01696,K01817 - 4.2.1.20,5.3.1.24 0.0000000000000000000000000000004215 129.0
CH2_k127_4813610_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 4.129e-287 889.0
CH2_k127_4813610_1 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 1.522e-240 751.0
CH2_k127_4813610_2 PFAM amine oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 606.0
CH2_k127_4813610_3 COG0438 Glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 401.0
CH2_k127_4813610_4 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007101 266.0
CH2_k127_4813610_5 ATP-dependent DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000002943 219.0
CH2_k127_4813610_6 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000579 203.0
CH2_k127_4813610_7 dna ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000008447 174.0
CH2_k127_4883509_0 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 481.0
CH2_k127_4883509_1 TIGRFAM F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 315.0
CH2_k127_4883509_2 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 308.0
CH2_k127_4883509_3 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000000000000000000000000000000000000000000000000000000006333 237.0
CH2_k127_4883509_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000003788 215.0
CH2_k127_4883509_5 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000001764 177.0
CH2_k127_4883509_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000009509 93.0
CH2_k127_4893799_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 3.653e-298 923.0
CH2_k127_4893799_1 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 392.0
CH2_k127_4893799_2 methylase K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 365.0
CH2_k127_4893799_3 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 361.0
CH2_k127_4893799_4 Uroporphyrinogen III synthase HEM4 K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 288.0
CH2_k127_4893799_5 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000008887 265.0
CH2_k127_4893799_6 - - - - 0.00000000000000000000000000000000000000000000000000006163 192.0
CH2_k127_4893799_7 - - - - 0.00000000000000000000003043 106.0
CH2_k127_4893799_8 SMART Elongator protein 3 MiaB NifB K15865 - 2.8.4.5 0.00001041 48.0
CH2_k127_4908566_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 514.0
CH2_k127_4908566_1 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 507.0
CH2_k127_4908566_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 411.0
CH2_k127_4908566_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007359 321.0
CH2_k127_4908566_4 methanogen marker protein 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009967 265.0
CH2_k127_4908566_5 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000015 252.0
CH2_k127_4908566_6 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000003 233.0
CH2_k127_4908566_7 transcription factor (CBF NF-Y) - - - 0.000000000000000000000000001202 112.0
CH2_k127_4908566_8 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000002685 59.0
CH2_k127_4913710_0 Belongs to the MCM family K10726 - - 0.0 1095.0
CH2_k127_4913710_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 505.0
CH2_k127_4913710_2 PFAM TatD-related deoxyribonuclease K07049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 328.0
CH2_k127_4913710_3 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000000002581 137.0
CH2_k127_5241189_0 sugar phosphatases of the HAD superfamily K02566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001144 273.0
CH2_k127_5241189_1 PFAM PEGA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005369 276.0
CH2_k127_5241189_2 COG0518 GMP synthase - Glutamine amidotransferase domain K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000005941 205.0
CH2_k127_5241189_3 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000001175 159.0
CH2_k127_5349482_0 PFAM dihydropteroate synthase, DHPS - - - 1.682e-198 628.0
CH2_k127_5349482_1 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 319.0
CH2_k127_5349482_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000007591 262.0
CH2_k127_5349482_3 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000004507 213.0
CH2_k127_5349482_4 Prokaryotic homologs of the JAB domain - - - 0.00000000000000000000000000000000000000000000000000000000003785 212.0
CH2_k127_5349482_5 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.000000000000000000000000000000000000000000001887 170.0
CH2_k127_5349482_6 - - - - 0.00000000000000000000000000000000000000001385 156.0
CH2_k127_5371694_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.344e-240 755.0
CH2_k127_5371694_1 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 535.0
CH2_k127_5371694_2 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 446.0
CH2_k127_5371694_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 411.0
CH2_k127_5373086_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 5.584e-194 621.0
CH2_k127_5373086_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 443.0
CH2_k127_5373086_2 PFAM carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001528 280.0
CH2_k127_5373086_3 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000001904 235.0
CH2_k127_5373086_4 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000000000000000000005104 229.0
CH2_k127_5373086_5 - - - - 0.0000000000000000000000000000000005805 134.0
CH2_k127_5373086_6 Glutaredoxin - - - 0.0000000000000000000000000000000009364 132.0
CH2_k127_5373086_7 - - - - 0.000000000000000000000000000000006323 130.0
CH2_k127_5373086_8 - - - - 0.0000000000000001521 85.0
CH2_k127_5393431_0 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 602.0
CH2_k127_5393431_1 PFAM oxidoreductase nitrogenase, component 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008379 340.0
CH2_k127_5393431_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000001381 230.0
CH2_k127_5393431_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000004037 176.0
CH2_k127_5393431_4 - - - - 0.0000000000000000000000001346 111.0
CH2_k127_5393431_5 PFAM oxidoreductase nitrogenase, component 1 - - - 0.00000000000000001838 85.0
CH2_k127_5397676_0 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 8.046e-231 725.0
CH2_k127_5397676_1 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 464.0
CH2_k127_5397676_2 Translation initiation factor 2 alpha subunit K03237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 366.0
CH2_k127_5397676_3 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001478 267.0
CH2_k127_5397676_4 binds to the 23S rRNA K02929 - - 0.0000000000000000000000000000000000000000000000000003163 184.0
CH2_k127_5397676_5 protein conserved in archaea K09723 - - 0.00000000000000000000000000000000000000000000000006203 187.0
CH2_k127_5397676_6 metal-binding protein - - - 0.000000000000000000000000000001255 123.0
CH2_k127_5397676_7 PFAM Ribosomal protein S27E K02978 - - 0.0000000000000000000001645 98.0
CH2_k127_5397676_8 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000009464 71.0
CH2_k127_5438897_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 540.0
CH2_k127_5438897_1 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 340.0
CH2_k127_5438897_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005396 258.0
CH2_k127_5438897_3 cytidyltransferase-related domain K00952 - 2.7.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000002771 252.0
CH2_k127_5438897_4 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000006256 185.0
CH2_k127_5469972_0 Uncharacterized membrane protein (DUF2298) - - - 1.455e-220 703.0
CH2_k127_5469972_1 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 377.0
CH2_k127_5469972_2 PFAM Glycosyl transferase family 2 K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 314.0
CH2_k127_5469972_3 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000009288 209.0
CH2_k127_5469972_4 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.000000000000000000000000000000000000000000000000000000009235 199.0
CH2_k127_5469972_5 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.00000000000000000000000000000000002887 134.0
CH2_k127_5639225_0 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005924 461.0
CH2_k127_5639225_1 archaeal Zn-finger protein - - - 0.00000000000000000000000000000000000000000000000000000000002353 212.0
CH2_k127_5639225_2 Domain of unknown function (DUF371) K09738 - - 0.00000000000000000000000000000000000000000000001115 175.0
CH2_k127_5639225_3 - - - - 0.000000000000000000000000000000001529 138.0
CH2_k127_5639225_4 Thioredoxin K03671 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000001858 91.0
CH2_k127_5639225_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000001086 55.0
CH2_k127_5663805_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 466.0
CH2_k127_5663805_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 362.0
CH2_k127_5663805_2 Radical SAM ThiC family K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000001548 243.0
CH2_k127_5663805_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000004734 239.0
CH2_k127_5842749_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 545.0
CH2_k127_5842749_1 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 409.0
CH2_k127_5842749_2 Type I restriction-modification system methyltransferase subunit - - - 0.0000000000000000000000000000000000000000000009965 176.0
CH2_k127_5915759_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1334.0
CH2_k127_5915759_1 inorganic K15986 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 294.0
CH2_k127_5923516_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1084.0
CH2_k127_5923516_1 4-Hydroxyphenylpyruvate dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 419.0
CH2_k127_5923516_2 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 408.0
CH2_k127_5923516_3 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 368.0
CH2_k127_5923516_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008117 264.0
CH2_k127_5923516_5 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000000000000008892 238.0
CH2_k127_5923516_6 Ferritin-like domain K02217 - 1.16.3.2 0.00000000000000000000000000001045 121.0
CH2_k127_5923516_7 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000001437 98.0
CH2_k127_5933734_0 PFAM phosphoesterase, RecJ domain protein K07463 - - 1.451e-194 617.0
CH2_k127_5933734_1 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 329.0
CH2_k127_5933734_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000001616 175.0
CH2_k127_5933734_3 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000000000000000000000000011 150.0
CH2_k127_6298243_0 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 572.0
CH2_k127_6298243_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 559.0
CH2_k127_6298243_10 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000001303 82.0
CH2_k127_6298243_11 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000002083 79.0
CH2_k127_6298243_2 ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 438.0
CH2_k127_6298243_3 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 388.0
CH2_k127_6298243_4 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 378.0
CH2_k127_6298243_5 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 374.0
CH2_k127_6298243_6 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 283.0
CH2_k127_6298243_7 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 284.0
CH2_k127_6298243_8 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004273 270.0
CH2_k127_6298243_9 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000001203 118.0
CH2_k127_6619289_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 474.0
CH2_k127_6619289_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 460.0
CH2_k127_6619289_10 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000006118 190.0
CH2_k127_6619289_11 - - - - 0.000000000000000000000000000000000000000000000004758 178.0
CH2_k127_6619289_12 Nitroreductase - - - 0.00000000000000000000000000000000000000000000001104 186.0
CH2_k127_6619289_13 CBS domain - - - 0.000000000000000000000000000000001691 133.0
CH2_k127_6619289_14 methanogenesis marker protein 11 - - - 0.000000000000001889 79.0
CH2_k127_6619289_15 Repeated motif present between transmembrane helices in cystinosin, yeast ERS1p, mannose-P-dolichol utilization defect 1, and other hypothetical proteins. K15383 - - 0.00000000004793 67.0
CH2_k127_6619289_2 PFAM ABC transporter related K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 412.0
CH2_k127_6619289_3 AAA ATPase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 392.0
CH2_k127_6619289_4 permease K03299 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 377.0
CH2_k127_6619289_5 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 330.0
CH2_k127_6619289_6 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 288.0
CH2_k127_6619289_7 NAD(P)H-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002503 267.0
CH2_k127_6619289_8 PFAM Isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001235 243.0
CH2_k127_6619289_9 amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002952 224.0
CH2_k127_6790145_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 291.0
CH2_k127_6790145_1 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000175 210.0
CH2_k127_6790145_2 protein involved in the oxidation of intracellular sulfur K07235,K07236 - - 0.0000000000000000000000000000000000000000000000000000000001282 218.0
CH2_k127_6790145_3 - K07112 - - 0.000000000000000000000000000000000000000000000002136 178.0
CH2_k127_6790145_4 - - - - 0.00000000000001348 74.0
CH2_k127_6790145_5 Small multi-drug export protein - - - 0.0000000000002376 73.0
CH2_k127_6853607_0 NADPH-dependent FMN reductase K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 310.0
CH2_k127_6853607_1 PFAM Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000003219 228.0
CH2_k127_6853607_2 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000000009313 207.0
CH2_k127_6853607_3 Proline dehydrogenase K00318 - - 0.00000000000000000007645 100.0
CH2_k127_6853607_4 - - - - 0.000000005269 61.0
CH2_k127_712257_0 Protein-export membrane protein SecD K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 600.0
CH2_k127_712257_1 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 299.0
CH2_k127_712257_2 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000002302 208.0
CH2_k127_712257_3 PFAM Thioredoxin K03671 - - 0.000000000000000000000000000000000001777 140.0
CH2_k127_728587_0 DEAD DEAH box helicase domain protein K10896 - - 7.645e-297 929.0
CH2_k127_728587_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 1.905e-282 876.0
CH2_k127_728587_2 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.00000000000000000000000001937 112.0
CH2_k127_728587_3 - - - - 0.000001943 49.0
CH2_k127_7348294_0 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 472.0
CH2_k127_7348294_1 TIGRFAM small GTP-binding protein K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 417.0
CH2_k127_7348294_2 SMART Peptidase A22, presenilin signal peptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 311.0
CH2_k127_7348294_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001826 261.0
CH2_k127_7348294_4 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000001555 219.0
CH2_k127_7348294_5 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000005079 76.0
CH2_k127_7348294_6 - - - - 0.00000000000002355 78.0
CH2_k127_742752_0 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 572.0
CH2_k127_742752_1 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 442.0
CH2_k127_742752_10 CHAD domain containing protein - - - 0.0006313 48.0
CH2_k127_742752_2 ATPases associated with a variety of cellular activities K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 316.0
CH2_k127_742752_3 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 312.0
CH2_k127_742752_4 Zinc-uptake complex component A periplasmic K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000004458 239.0
CH2_k127_742752_5 Crossover junction endodeoxyribonuclease RuvC K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000001033 188.0
CH2_k127_742752_6 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000004882 190.0
CH2_k127_742752_7 iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000003909 171.0
CH2_k127_742752_8 RuvA, C-terminal domain K03550 - 3.6.4.12 0.000000000000000000000000000000000000000001629 163.0
CH2_k127_742752_9 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000003597 53.0
CH2_k127_7439457_0 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 483.0
CH2_k127_7439457_1 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004014 272.0
CH2_k127_7439457_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000677 252.0
CH2_k127_7439457_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0002999 44.0
CH2_k127_7531268_0 PFAM AIR synthase related protein K07388 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 545.0
CH2_k127_7531268_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 463.0
CH2_k127_7531268_2 Replication factor C K04801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 367.0
CH2_k127_7531268_3 pfam nmd3 K07562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 344.0
CH2_k127_7531268_4 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 318.0
CH2_k127_7531268_5 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 306.0
CH2_k127_7531268_6 PFAM GHMP kinase K06982 - 2.7.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005811 274.0
CH2_k127_7531268_7 Pfam:DUF137 K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000000005374 254.0
CH2_k127_7531268_8 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000001307 114.0
CH2_k127_7593087_0 Phosphate transport regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006238 505.0
CH2_k127_7593087_1 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 456.0
CH2_k127_7593087_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 417.0
CH2_k127_7593087_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 364.0
CH2_k127_7593087_4 Domain of unknown function DUF128 K21640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 335.0
CH2_k127_7673004_0 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 6.479e-302 930.0
CH2_k127_7673004_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 441.0
CH2_k127_7673004_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000000000000000000009573 136.0
CH2_k127_7852298_0 Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 468.0
CH2_k127_7852298_1 PFAM metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 336.0
CH2_k127_7852298_2 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 297.0
CH2_k127_7852298_3 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000003498 198.0
CH2_k127_7852298_4 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000000000000000000000557 196.0
CH2_k127_7852298_5 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.000000000000000000000000000000000000000000000000000005051 192.0
CH2_k127_7852298_6 TIR domain - - - 0.0000000000000005439 84.0
CH2_k127_7859103_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 474.0
CH2_k127_7859103_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 460.0
CH2_k127_7859103_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 458.0
CH2_k127_7859103_3 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 352.0
CH2_k127_7859103_4 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 319.0
CH2_k127_7859103_5 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 294.0
CH2_k127_7859103_6 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 281.0
CH2_k127_7859103_7 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000000000004903 188.0
CH2_k127_7903969_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 543.0
CH2_k127_7903969_1 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 432.0
CH2_k127_7903969_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 364.0
CH2_k127_7903969_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 351.0
CH2_k127_7903969_4 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 342.0
CH2_k127_7903969_5 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.000000000000000000000000000000000000000000000000000000000005926 216.0
CH2_k127_7903969_6 unfolded protein binding - - - 0.00000000000000004062 83.0
CH2_k127_7903969_7 Protein of unknown function (DUF2997) - - - 0.000007971 50.0
CH2_k127_8084306_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.751e-231 721.0
CH2_k127_8084306_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 8.19e-223 701.0
CH2_k127_8084306_2 DEAD DEAH box helicase K03724 - - 1.611e-204 650.0
CH2_k127_8084306_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000006133 212.0
CH2_k127_8084306_4 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000006725 153.0
CH2_k127_8084306_5 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.0000000000000000000000000000004645 122.0
CH2_k127_8084306_6 binds to the 23S rRNA K02922 - - 0.00000000000000000000000003433 108.0
CH2_k127_8084306_7 - - - - 0.000000001762 58.0
CH2_k127_8360626_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 7.729e-296 915.0
CH2_k127_8360626_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.11e-259 805.0
CH2_k127_8360626_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007068 258.0
CH2_k127_8360626_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000007646 222.0
CH2_k127_8360626_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000000000000019 139.0
CH2_k127_8376955_0 - - - - 0.000000000000000000000000000000000000000000000000001468 190.0
CH2_k127_8376955_1 PFAM response regulator receiveR - - - 0.000000000000000000000000000000000000000000000000003546 186.0
CH2_k127_8376955_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000526 181.0
CH2_k127_8376955_3 sensor histidine kinase - - - 0.00000000000000000000000000000000000000002185 154.0
CH2_k127_853351_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 1.319e-299 925.0
CH2_k127_853351_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 526.0
CH2_k127_853351_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 454.0
CH2_k127_853351_3 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000001586 201.0
CH2_k127_8554190_0 Belongs to the glutamate synthase family - - - 1.022e-273 848.0
CH2_k127_8554190_1 PFAM glutamine amidotransferase, class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 548.0
CH2_k127_8554190_2 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 434.0
CH2_k127_8554190_3 PFAM glutamate synthase alpha subunit domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 340.0
CH2_k127_8556354_0 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 1.314e-285 885.0
CH2_k127_8556354_1 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 1.147e-214 673.0
CH2_k127_8556354_2 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 301.0
CH2_k127_8556354_3 - - - - 0.0000000000000000000000002097 105.0
CH2_k127_8556354_4 PFAM molydopterin dinucleotide-binding region K00203 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 1.2.7.12 0.0000002692 53.0
CH2_k127_8611039_0 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 376.0
CH2_k127_8611039_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 333.0
CH2_k127_8611039_10 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.00003529 49.0
CH2_k127_8611039_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008912 261.0
CH2_k127_8611039_3 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.00000000000000000000000000000000000000000000000005972 182.0
CH2_k127_8611039_4 - - - - 0.000000000000000000000000000000000006783 141.0
CH2_k127_8611039_5 transcription factor (CBF NF-Y) - - - 0.0000000000000000000008495 96.0
CH2_k127_8611039_6 - - - - 0.000000000000000003324 87.0
CH2_k127_8611039_7 PFAM TPR repeat-containing protein - - - 0.000000000000000008087 87.0
CH2_k127_8611039_8 Tetratricopeptide repeat - - - 0.00000000001934 68.0
CH2_k127_8611039_9 membrane - - - 0.00000001643 65.0
CH2_k127_8813525_0 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 499.0
CH2_k127_8813525_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 416.0
CH2_k127_8813525_2 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 331.0
CH2_k127_8813525_3 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 299.0
CH2_k127_8819562_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 573.0
CH2_k127_8819562_1 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 573.0
CH2_k127_8819562_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 386.0
CH2_k127_8819562_3 protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000001215 224.0
CH2_k127_8819562_4 Protein of unknown function (DUF2769) - - - 0.00000000000000000000000000000000000000002582 154.0
CH2_k127_8819562_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000007775 127.0
CH2_k127_8888264_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 554.0
CH2_k127_8888264_1 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 525.0
CH2_k127_8888264_2 PFAM triphosphoribosyl-dephospho-CoA protein K05966 - 2.4.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 368.0
CH2_k127_8888264_3 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000002537 218.0
CH2_k127_8888264_4 Protein of unknown function (DUF447) K09154 - - 0.00000000000000000000000000000000000000000000006295 175.0
CH2_k127_8888264_5 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000000003724 160.0
CH2_k127_8888264_6 Dihydrouridine synthase (Dus) - - - 0.00000000000000005406 82.0
CH2_k127_8920081_0 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 584.0
CH2_k127_8920081_1 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 332.0
CH2_k127_8920081_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000004761 218.0
CH2_k127_8920081_3 PFAM Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000004773 199.0
CH2_k127_8920081_4 COG1881 Phospholipid-binding protein K06910 - - 0.00000000000000000000000000000000000000000000003604 173.0
CH2_k127_8920081_5 - - - - 0.00000000000000000000000000000000000007917 149.0
CH2_k127_8920081_6 - K06868 - 2.5.1.73 0.00000000000001087 75.0
CH2_k127_8920081_7 N-formylglutamate amidohydrolase K01479 - 3.5.3.8 0.0005623 44.0
CH2_k127_9122761_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 459.0
CH2_k127_9122761_1 zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000003472 214.0
CH2_k127_9122761_2 Uncharacterised conserved protein UCP033563 - - - 0.00000000000000000000000000000000000000000000000000001302 191.0
CH2_k127_9122761_3 Ribonuclease K03469 - 3.1.26.4 0.0000000000000000000000005294 113.0
CH2_k127_9144415_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 428.0
CH2_k127_9144415_1 Domain of unknown function (DUF1848) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 371.0
CH2_k127_9167018_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 548.0
CH2_k127_9167018_1 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008909 531.0
CH2_k127_9167018_2 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 363.0
CH2_k127_9167018_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 329.0
CH2_k127_9167018_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000003195 218.0
CH2_k127_9167018_5 TfuA-like protein - - - 0.000000000000000000000000000000000000007654 153.0
CH2_k127_9194890_0 KH, type 1, domain K07041 - - 2.295e-245 763.0
CH2_k127_9194890_1 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 429.0
CH2_k127_9194890_2 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 384.0
CH2_k127_9194890_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 332.0
CH2_k127_9194890_4 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000001788 176.0
CH2_k127_9260375_0 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 594.0
CH2_k127_9260375_1 PFAM elongation factor Tu domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 323.0
CH2_k127_9260375_2 PFAM LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 289.0
CH2_k127_9266618_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.72e-283 886.0
CH2_k127_9377329_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 2.968e-200 630.0
CH2_k127_9377329_1 Pas domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 523.0
CH2_k127_9377329_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 379.0
CH2_k127_9377329_3 Helix-turn-helix domain protein K03627 - - 0.0000000000000000000000000000000000000000000000000005236 188.0
CH2_k127_9416824_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 1.799e-211 667.0
CH2_k127_9416824_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 345.0
CH2_k127_9416824_2 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 340.0
CH2_k127_9416824_3 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000000012 169.0
CH2_k127_9416824_4 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.00000000000000001369 85.0
CH2_k127_9445446_0 PFAM ABC transporter K00400 - - 1.554e-279 866.0
CH2_k127_9445446_1 Belongs to the UPF0288 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 591.0
CH2_k127_9445446_2 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.00000000000000000000000000000000000000000000000000000007958 198.0
CH2_k127_9445446_3 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.000000002702 59.0
CH2_k127_9494401_0 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 421.0
CH2_k127_9494401_1 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 416.0
CH2_k127_9494401_2 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 380.0
CH2_k127_9494401_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 379.0
CH2_k127_9494401_4 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000005287 140.0
CH2_k127_9494401_5 protein conserved in archaea - - - 0.0000000000000000000000000000000002347 134.0
CH2_k127_9494401_6 - - - - 0.000000000000134 72.0
CH2_k127_9816402_0 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 558.0
CH2_k127_9816402_1 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 313.0
CH2_k127_9816402_2 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 287.0
CH2_k127_9816402_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000000000006098 124.0
CH2_k127_9816402_4 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000001135 122.0
CH2_k127_9816402_5 CRS1_YhbY K07574 - - 0.00000000000000000000000002195 109.0
CH2_k127_9816402_6 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.000000000000000000000468 97.0
CH2_k127_9863550_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 391.0
CH2_k127_9863550_1 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934 - 2.1.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 354.0
CH2_k127_9863550_2 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 352.0
CH2_k127_9863550_3 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 311.0
CH2_k127_9863550_4 PFAM cobalamin (vitamin B12) biosynthesis CbiG protein K02189 - 3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 288.0
CH2_k127_9863550_5 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000000242 262.0
CH2_k127_9863550_6 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000001553 240.0
CH2_k127_9863550_7 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000003325 215.0
CH2_k127_9863550_8 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.000000000000000000000000000000000000000000000000004859 186.0
CH2_k127_9863550_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.000000004378 57.0
CH2_k127_9921179_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 3.989e-308 970.0
CH2_k127_9921179_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 535.0
CH2_k127_9921179_2 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 509.0
CH2_k127_9921179_3 COG1194 A G-specific DNA glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 290.0
CH2_k127_9921179_4 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000003565 180.0
CH2_k127_9960829_0 Belongs to the RtcB family K14415 - 6.5.1.3 1.979e-225 706.0
CH2_k127_9960829_1 Involved in protein export K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 374.0
CH2_k127_9960829_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001797 238.0
CH2_k127_9960829_3 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.000000000000000000000000000000000000000000000000000000000006233 211.0
CH2_k127_9960829_4 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000001314 147.0
CH2_k127_9960829_5 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000006909 126.0
CH2_k127_9960829_6 Protein of unknown function (DUF2551) - - - 0.0000000000000000000000000000001785 125.0
CH2_k127_9960829_7 - - - - 0.0000000000000000000000001899 108.0