Overview

ID MAG00260
Name CH2_bin.55
Sample SMP0008
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Beggiatoales
Family Beggiatoaceae
Genus
Species
Assembly information
Completeness (%) 78.96
Contamination (%) 0.67
GC content (%) 36.0
N50 (bp) 4,147
Genome size (bp) 2,043,853

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1871

Gene name Description KEGG GOs EC E-value Score Sequence
CH2_k127_10009566_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 596.0
CH2_k127_10009566_1 PFAM Cobyrinic acid a,c-diamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001012 250.0
CH2_k127_10009566_2 STAS domain - - - 0.0000000000385 71.0
CH2_k127_10073879_0 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 294.0
CH2_k127_10073879_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000005841 188.0
CH2_k127_10073879_2 PFAM Ferrous iron transporter, FeoA subunit K04758 - - 0.0000000000000000000000001272 107.0
CH2_k127_10252809_0 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 558.0
CH2_k127_10252809_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.000000000000000000006385 96.0
CH2_k127_1026501_0 Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism K02567 - - 0.0 1495.0
CH2_k127_1026501_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004596 261.0
CH2_k127_1026501_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000085 275.0
CH2_k127_10293131_0 Diguanylate cyclase - - - 3.007e-198 670.0
CH2_k127_10293131_1 GTP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000003191 242.0
CH2_k127_10293134_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000004461 194.0
CH2_k127_10293134_1 PFAM chemotaxis K03406 - - 0.00000000002389 76.0
CH2_k127_10294018_0 Belongs to the N(4) N(6)-methyltransferase family K00571,K13581 - 2.1.1.72 3.644e-204 639.0
CH2_k127_10294018_1 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 424.0
CH2_k127_10294018_2 phosphate ion binding K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006865 283.0
CH2_k127_10294018_3 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000003082 145.0
CH2_k127_1029819_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 503.0
CH2_k127_1029819_1 Protein of unknown function DUF262 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 445.0
CH2_k127_1029819_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 346.0
CH2_k127_10314179_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 401.0
CH2_k127_10314179_1 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000004451 120.0
CH2_k127_10326618_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1199.0
CH2_k127_10326618_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 424.0
CH2_k127_10326618_2 - - - - 0.0000000000003743 73.0
CH2_k127_10337065_0 Belongs to the aldehyde dehydrogenase family K00128,K00135,K22187 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 438.0
CH2_k127_10337065_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000002277 139.0
CH2_k127_10337065_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000004903 80.0
CH2_k127_1034656_0 Adenine specific DNA methylase Mod K00571,K07316,K07319 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 446.0
CH2_k127_1034656_1 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000005265 188.0
CH2_k127_1034656_2 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000004147 173.0
CH2_k127_10347659_0 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 427.0
CH2_k127_10347659_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000003606 181.0
CH2_k127_10347659_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000007645 51.0
CH2_k127_10350036_0 site-specific DNA-methyltransferase (adenine-specific) activity K03427 - 2.1.1.72 5.913e-230 734.0
CH2_k127_10350036_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000001784 165.0
CH2_k127_10352522_0 SERine Proteinase INhibitors K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 342.0
CH2_k127_10352522_1 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015886,GO:0016020,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051234,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097159,GO:0098552,GO:0098567,GO:1901363,GO:1901564,GO:1901678 - 0.000000000000000000000000000005132 120.0
CH2_k127_1035253_0 ABC-type branched-chain amino acid transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 488.0
CH2_k127_1035253_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000000000000000000000000003882 209.0
CH2_k127_1035253_2 cyclic nucleotide binding K15762 - - 0.000000000000008829 89.0
CH2_k127_10371509_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008983 369.0
CH2_k127_10371509_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000006093 48.0
CH2_k127_10371509_2 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.0007058 43.0
CH2_k127_10376804_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 375.0
CH2_k127_10376804_1 - - - - 0.000539 43.0
CH2_k127_10391627_0 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 458.0
CH2_k127_10391627_1 Histidine kinase A domain protein K07678 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 450.0
CH2_k127_10391627_2 Domain of unknown function DUF29 - - - 0.00000000000000000000000000006053 118.0
CH2_k127_10405742_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 379.0
CH2_k127_10405742_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 352.0
CH2_k127_10405742_2 PFAM Transposase - - - 0.0000000004006 61.0
CH2_k127_10422969_0 HsdM N-terminal domain K03427 - 2.1.1.72 1.214e-196 624.0
CH2_k127_10422969_1 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.000000000000000000000000000000000000000000000000001705 207.0
CH2_k127_10431212_0 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000005859 231.0
CH2_k127_10431212_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000007865 154.0
CH2_k127_10431212_2 Caspase domain - - - 0.00007521 51.0
CH2_k127_10432164_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 534.0
CH2_k127_10433829_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 551.0
CH2_k127_10433829_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004017 278.0
CH2_k127_10433829_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0071704,GO:1901564,GO:1902494 6.2.1.5 0.0000000000000000000000004387 104.0
CH2_k127_10433991_0 PFAM sodium alanine symporter K03310 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 596.0
CH2_k127_10433991_1 oxidoreductase activity K02012,K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 381.0
CH2_k127_10433991_2 7TM diverse intracellular signalling K19694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 366.0
CH2_k127_10433991_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000006633 184.0
CH2_k127_10433991_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K07216,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000001096 131.0
CH2_k127_10438928_0 - - - - 0.000000000000000000000000000000000000000000000000000000000005809 213.0
CH2_k127_10438928_1 Produces ATP from ADP in the presence of a proton gradient across the membrane - - - 0.0000000000000000000000000001887 117.0
CH2_k127_10439145_0 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 522.0
CH2_k127_10439145_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K19694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 433.0
CH2_k127_10439145_2 Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000001112 162.0
CH2_k127_10439145_3 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000000009058 98.0
CH2_k127_10449587_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 442.0
CH2_k127_10449587_1 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000008151 171.0
CH2_k127_10449587_2 peptidoglycan binding K03642 - - 0.000000000000000000006195 97.0
CH2_k127_10497830_0 Type II and III secretion system protein K02453 - - 3.051e-233 739.0
CH2_k127_10497830_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 3.055e-218 684.0
CH2_k127_10497830_10 COG NOG15344 non supervised orthologous group - - - 0.00000000000000000000000000001163 118.0
CH2_k127_10497830_11 - - - - 0.000000000000000000000002376 102.0
CH2_k127_10497830_12 - - - - 0.0000000000000000000003958 96.0
CH2_k127_10497830_13 - - - - 0.000000000000000000002084 93.0
CH2_k127_10497830_14 - - - - 0.0000000000000000002113 89.0
CH2_k127_10497830_16 - - - - 0.000000000000004313 78.0
CH2_k127_10497830_17 - - - - 0.000000000000008361 74.0
CH2_k127_10497830_18 Haloacid dehalogenase-like hydrolase K00817 - 2.6.1.9 0.0000000000002342 79.0
CH2_k127_10497830_2 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 584.0
CH2_k127_10497830_20 - - - - 0.0000000000007216 68.0
CH2_k127_10497830_21 - - - - 0.000000000001381 69.0
CH2_k127_10497830_23 - - - - 0.0000000004938 63.0
CH2_k127_10497830_24 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00005724 46.0
CH2_k127_10497830_25 - - - - 0.0009593 44.0
CH2_k127_10497830_3 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 320.0
CH2_k127_10497830_4 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 316.0
CH2_k127_10497830_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000002009 217.0
CH2_k127_10497830_6 by Glimmer3 - - - 0.0000000000000000000000000000000000000000000000005277 175.0
CH2_k127_10497830_7 Protein of unknown function (DUF3426) - - - 0.000000000000000000000000000000000000000000000007498 180.0
CH2_k127_10497830_8 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000001496 161.0
CH2_k127_10497830_9 - - - - 0.000000000000000000000000000000007505 128.0
CH2_k127_10499501_0 Cytochrome B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 333.0
CH2_k127_10499501_1 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 286.0
CH2_k127_10499501_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003126 281.0
CH2_k127_10499501_3 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000000000001076 155.0
CH2_k127_10499501_4 PFAM Di-haem cytochrome c - - - 0.000000000000000000000000000000000000001287 154.0
CH2_k127_10505115_0 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 517.0
CH2_k127_10505115_1 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 352.0
CH2_k127_10505115_2 PFAM cytochrome c - - - 0.000000000000000000000000000000000000000000000000001069 190.0
CH2_k127_10505115_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000028 164.0
CH2_k127_10505115_4 signal sequence binding K07152 - - 0.00000000000000000000000000000000000000007731 162.0
CH2_k127_10505115_5 cytochrome c oxidase, subunit III K02276 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.000000000000000000000000000000000000007994 154.0
CH2_k127_1052524_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.246e-211 666.0
CH2_k127_1052524_1 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000454 392.0
CH2_k127_1052524_2 Alkaline phosphatase homologues K01077 GO:0000287,GO:0003674,GO:0003824,GO:0004035,GO:0004721,GO:0005488,GO:0005575,GO:0005623,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016491,GO:0016695,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0030288,GO:0030313,GO:0030613,GO:0031975,GO:0033748,GO:0036211,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0140096,GO:1901564 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 320.0
CH2_k127_1052524_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K09565 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016018,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0033218,GO:0036211,GO:0042277,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043900,GO:0043903,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045069,GO:0050789,GO:0050792,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1903900 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001967 258.0
CH2_k127_1052524_4 S1 P1 nuclease - - - 0.0000000000000000000000000000000000000000002181 161.0
CH2_k127_1052524_5 - - - - 0.0000000000000000000000007083 117.0
CH2_k127_10557690_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000003225 149.0
CH2_k127_10557690_1 Acetyltransferase (GNAT) domain - - - 0.0001665 45.0
CH2_k127_10565235_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 537.0
CH2_k127_10565235_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 319.0
CH2_k127_10565235_2 - - - - 0.00000000000000000000000000000000002491 140.0
CH2_k127_10565235_3 chaperone-mediated protein folding - - - 0.000000000000000000000000000000001283 138.0
CH2_k127_10565235_4 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000103 113.0
CH2_k127_1058313_0 CHAD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 408.0
CH2_k127_1058313_1 Cellulose biosynthesis protein BcsQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 325.0
CH2_k127_1058313_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000706 227.0
CH2_k127_1058313_3 TIGRFAM lipopolysaccharide heptosyltransferase I K02841 - - 0.000000000000000000000000000000000000000000000000000000000001171 214.0
CH2_k127_1058313_4 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000158 205.0
CH2_k127_10608390_0 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 490.0
CH2_k127_10608390_1 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000000000000000007588 157.0
CH2_k127_10608390_2 chlorophyll binding K03640 - - 0.0000000002408 67.0
CH2_k127_10654312_0 Conserved hypothetical ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000233 271.0
CH2_k127_10654312_1 TIGRFAM RNA polymerase sigma factor RpoS K03087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001974 270.0
CH2_k127_10654312_2 - - - - 0.000000000000000000000000000000000000000000000000000000000004322 219.0
CH2_k127_10654312_3 transcription factor binding - - - 0.00000000000000000000000000000000000000000000000000000007966 199.0
CH2_k127_10654312_4 Peptidase family M23 K06194 - - 0.0000000000000000000000000000000000000000000006095 176.0
CH2_k127_10654312_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000424 73.0
CH2_k127_10690854_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 406.0
CH2_k127_10690854_1 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 304.0
CH2_k127_10690854_2 - - - - 0.0000000000000000000000000000000000000000000000000005936 199.0
CH2_k127_10690854_3 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000004344 153.0
CH2_k127_10690854_4 - - - - 0.00000000000000000000000000005513 118.0
CH2_k127_1070400_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000219 244.0
CH2_k127_1070400_1 GDA1/CD39 (nucleoside phosphatase) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 235.0
CH2_k127_1070400_3 - - - - 0.00000000000001075 81.0
CH2_k127_10726539_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 586.0
CH2_k127_10726539_1 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 471.0
CH2_k127_10726539_2 Glycosyl transferases group 1 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 385.0
CH2_k127_10726539_3 PFAM NAD-dependent epimerase dehydratase K15856,K22252 - 1.1.1.135,1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 346.0
CH2_k127_10736025_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 9.868e-319 993.0
CH2_k127_10736025_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 493.0
CH2_k127_10736025_2 Proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 314.0
CH2_k127_10736025_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000009414 248.0
CH2_k127_10736025_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003753 239.0
CH2_k127_10736025_5 MORN repeat variant - - - 0.000000000000000000000000000000000000000000000000000000000000004251 223.0
CH2_k127_10736025_6 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000007483 178.0
CH2_k127_10736025_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000001443 163.0
CH2_k127_10752059_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 518.0
CH2_k127_10752059_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000001748 238.0
CH2_k127_10752059_2 PFAM WD domain, G-beta repeat - - - 0.000000000000000000000000000000004024 136.0
CH2_k127_10752934_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 390.0
CH2_k127_10752934_1 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 315.0
CH2_k127_10752934_2 possibly involved in cell wall synthesis K06925 GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000003603 170.0
CH2_k127_10760183_0 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 408.0
CH2_k127_10760183_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000006811 175.0
CH2_k127_1076450_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930,K22478 GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 437.0
CH2_k127_1076450_1 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052913,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.171 0.00000000000000000000000000000000000000000000000000000002905 201.0
CH2_k127_1076450_2 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000000000003222 190.0
CH2_k127_1076450_3 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000009804 154.0
CH2_k127_1076450_4 Methyltransferase domain - - - 0.0000000000000000000000000000000005229 143.0
CH2_k127_10790612_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 297.0
CH2_k127_10790612_1 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000001161 128.0
CH2_k127_10814102_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001658 258.0
CH2_k127_10814102_1 methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0042084,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.00000000000000000000000000000000000000000000000000002159 189.0
CH2_k127_10814102_2 1-phosphatidylinositol-4-phosphate 5-kinase activity K14972 - - 0.000000000000000000000000000000000000000000875 168.0
CH2_k127_10814102_3 PFAM transposase IS4 family protein - - - 0.0000000003495 62.0
CH2_k127_10823413_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 588.0
CH2_k127_10823413_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 575.0
CH2_k127_10823413_2 Type II secretion system protein B K02451 - - 0.000000000000000001186 95.0
CH2_k127_10832514_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 560.0
CH2_k127_10832514_1 PFAM Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 370.0
CH2_k127_10832514_10 Parallel beta-helix repeats - - - 0.0000001353 59.0
CH2_k127_10832514_2 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 385.0
CH2_k127_10832514_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 317.0
CH2_k127_10832514_4 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000002119 265.0
CH2_k127_10832514_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000003806 228.0
CH2_k127_10832514_6 OmpA family K03640 - - 0.000000000000000000000000000000000000000000006775 169.0
CH2_k127_10832514_7 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000005086 158.0
CH2_k127_10832514_8 ATP synthase I chain K02116 - - 0.00000000000000000000000000001288 123.0
CH2_k127_10832514_9 - - - - 0.00000000000000003298 91.0
CH2_k127_10858700_0 3'-5' exonuclease K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 317.0
CH2_k127_10858700_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000052 237.0
CH2_k127_10858700_2 Protein of unknown function (DUF1318) - - - 0.00000000000000000000000000000000000000005605 154.0
CH2_k127_10861117_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 6.214e-235 739.0
CH2_k127_10861117_1 FeoC like transcriptional regulator - - - 0.0000000007165 60.0
CH2_k127_10872671_0 Belongs to the peptidase S1C family K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 477.0
CH2_k127_10872671_1 PFAM peptidase K08303 - - 0.00000000000479 67.0
CH2_k127_10874543_0 PFAM Squalene phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 421.0
CH2_k127_10874543_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 335.0
CH2_k127_10874543_2 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.00000000000007554 79.0
CH2_k127_10874543_3 - K02456 - - 0.000000000009521 66.0
CH2_k127_10879379_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 332.0
CH2_k127_10902147_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 593.0
CH2_k127_10902147_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 491.0
CH2_k127_10902147_2 - - - - 0.000000000005311 74.0
CH2_k127_10908374_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 466.0
CH2_k127_10908374_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 324.0
CH2_k127_10911065_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1066.0
CH2_k127_10911065_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 535.0
CH2_k127_10911065_2 His Kinase A (phosphoacceptor) domain - - - 0.000000004378 57.0
CH2_k127_10912316_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 2.776e-249 779.0
CH2_k127_10912316_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008113 511.0
CH2_k127_10924534_0 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 426.0
CH2_k127_10924534_1 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000001878 178.0
CH2_k127_10924534_2 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000006041 124.0
CH2_k127_10925989_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 568.0
CH2_k127_10925989_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 452.0
CH2_k127_10925989_2 Product type h extrachromosomal origin - - - 0.000007411 49.0
CH2_k127_10979098_0 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 8.286e-204 640.0
CH2_k127_10979098_1 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 282.0
CH2_k127_10979098_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000006384 267.0
CH2_k127_10979098_3 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.0000000000000003609 79.0
CH2_k127_10979098_4 PFAM IS1 transposase K07480 - - 0.0000005258 52.0
CH2_k127_10985342_0 response regulator receiver K02487,K06596 - - 7.664e-205 674.0
CH2_k127_10990095_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 443.0
CH2_k127_10990095_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000001163 170.0
CH2_k127_10990095_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000008672 105.0
CH2_k127_10990095_3 Cell wall formation K01921 - 6.3.2.4 0.000000009192 57.0
CH2_k127_11006932_0 Cytochrome c-type biogenesis protein CcmF C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 504.0
CH2_k127_11006932_1 - - - - 0.00006946 49.0
CH2_k127_1100774_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 485.0
CH2_k127_1100774_2 PIN domain - - - 0.00000000001836 68.0
CH2_k127_11013497_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 572.0
CH2_k127_11013497_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 322.0
CH2_k127_11021590_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.894e-281 871.0
CH2_k127_11021590_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000002836 156.0
CH2_k127_11021590_2 Pilin (bacterial filament) K02650 - - 0.000000000000004649 75.0
CH2_k127_11046685_0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 503.0
CH2_k127_11046685_1 Belongs to the ParA family K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 456.0
CH2_k127_11046685_2 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.000000000000000000000000000000000000000000000000000000000000000002819 233.0
CH2_k127_11046685_3 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.0000000000000000000000008075 106.0
CH2_k127_1108721_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007413 449.0
CH2_k127_1108721_1 PFAM Radical SAM K19810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001187 287.0
CH2_k127_11088569_0 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 304.0
CH2_k127_11088569_1 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002874 259.0
CH2_k127_11088569_2 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000006142 255.0
CH2_k127_1118871_0 reductase, alpha subunit K00394 - 1.8.99.2 0.0 1133.0
CH2_k127_1118871_1 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 281.0
CH2_k127_1118871_2 response regulator receiver K13041 - - 0.00000001045 59.0
CH2_k127_11194846_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.785e-257 802.0
CH2_k127_11194846_1 TIGRFAM ATP-dependent DNA helicase, RecQ K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 347.0
CH2_k127_11220157_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 372.0
CH2_k127_11228250_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 499.0
CH2_k127_11254925_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 436.0
CH2_k127_11263050_0 D-lactate dehydrogenase K18930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 613.0
CH2_k127_11285077_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 309.0
CH2_k127_11285077_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000000000000001258 147.0
CH2_k127_11285077_3 Protein of unknown function (DUF2283) - - - 0.00000005937 54.0
CH2_k127_11290136_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000679 190.0
CH2_k127_11290136_1 nodulation - - - 0.000000000000000000000000000000000000000879 151.0
CH2_k127_11290136_2 - - - - 0.000000000000000001357 87.0
CH2_k127_11290136_3 - - - - 0.000000000000000003453 96.0
CH2_k127_11312550_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 556.0
CH2_k127_11312550_1 Tetratricopeptide repeat - - - 0.00000000000000000000001433 102.0
CH2_k127_11312550_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000002997 55.0
CH2_k127_11330440_0 carbamoyl transferase, NodU family K00612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 403.0
CH2_k127_11330440_1 TIGRFAM cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000000000000000000000000002734 207.0
CH2_k127_11330440_2 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000001768 183.0
CH2_k127_11330440_3 - - - - 0.00000115 55.0
CH2_k127_11414761_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 606.0
CH2_k127_11414761_1 trisaccharide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 392.0
CH2_k127_11414761_2 TIGRFAM 1-acyl-sn-glycerol-3-phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000004704 192.0
CH2_k127_11414761_3 Belongs to the UPF0149 family K09895 - - 0.000000000000000000000000000000000000000001759 162.0
CH2_k127_11414761_4 Beta propeller domain - - - 0.000000000000003535 83.0
CH2_k127_11414844_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000001173 184.0
CH2_k127_11414844_1 Histidine kinase K03407 - 2.7.13.3 0.0000000000000000000002508 104.0
CH2_k127_11428634_0 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 388.0
CH2_k127_11428634_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 366.0
CH2_k127_11450944_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 355.0
CH2_k127_11450944_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 291.0
CH2_k127_11451561_0 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 605.0
CH2_k127_11451561_1 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 341.0
CH2_k127_11451561_2 Flavodoxin-like fold K11748 - - 0.00000000000000000000000000000000000000000000000000478 186.0
CH2_k127_11451561_3 COG4886 Leucine-rich repeat (LRR) protein - - - 0.0000000001491 69.0
CH2_k127_11463632_0 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 300.0
CH2_k127_11463632_1 TerD domain K05795 - - 0.000000000000000000000000000000000000000000000000000000000000006739 222.0
CH2_k127_11463632_2 - - - - 0.0005446 45.0
CH2_k127_1149509_0 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 410.0
CH2_k127_1149509_1 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 322.0
CH2_k127_1149509_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 304.0
CH2_k127_1149509_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000004304 175.0
CH2_k127_1149509_4 Protein of unknown function (DUF1566) - - - 0.0000000000000000006966 91.0
CH2_k127_1155094_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000008692 183.0
CH2_k127_1155094_1 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000002342 126.0
CH2_k127_1155094_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000002622 102.0
CH2_k127_1155094_3 Ribosomal protein L34 K02914 - - 0.00000000000001356 75.0
CH2_k127_11586567_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 463.0
CH2_k127_11604555_0 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 417.0
CH2_k127_11632_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 315.0
CH2_k127_11632_1 C-terminal of Roc, COR, domain K13730 - - 0.000000000000000000000000000000000000000000000003512 188.0
CH2_k127_11632_2 - - - - 0.0000000000000000000000000000000000000001304 166.0
CH2_k127_11690569_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 1.803e-314 975.0
CH2_k127_11690569_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 387.0
CH2_k127_11690569_2 TerD domain - - - 0.000000000000000000000000000000000000000000000002821 179.0
CH2_k127_11690569_3 C-terminal of Roc, COR, domain K13730 - - 0.000000008711 67.0
CH2_k127_11692756_0 Cytokinin dehydrogenase 1, FAD and cytokinin binding - - - 0.0000000000000000000005969 110.0
CH2_k127_11709162_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1060.0
CH2_k127_11709162_1 COG0846 NAD-dependent protein deacetylases, SIR2 family K12410 - - 0.000000000000000000000000000000000000000000000518 169.0
CH2_k127_1171713_0 Transposase - - - 3.262e-260 811.0
CH2_k127_1171713_1 response regulator - - - 2.185e-235 733.0
CH2_k127_1171713_2 PFAM Transposase - - - 0.00000000000000000000000000000000000000000000000000001568 192.0
CH2_k127_11719799_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 3.188e-315 983.0
CH2_k127_11719799_1 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 402.0
CH2_k127_11719799_2 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 285.0
CH2_k127_11719799_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004499 241.0
CH2_k127_11719799_4 PFAM WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000009566 252.0
CH2_k127_11719799_5 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006349 234.0
CH2_k127_11719799_6 Maf-like protein - - - 0.000000000000000000000000000000000000000000000000000000000001294 215.0
CH2_k127_11719799_7 PFAM MerR family regulatory protein - - - 0.0000000000000000000000000000000000000000000000002061 178.0
CH2_k127_11719799_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000002181 161.0
CH2_k127_11719799_9 Psort location Cytoplasmic, score - - - 0.0000000000000000000000004509 114.0
CH2_k127_11723767_0 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 370.0
CH2_k127_11723767_1 May be involved in recombination K03554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009937 319.0
CH2_k127_11723767_10 Chorismate mutase K00014,K00891,K04092,K04516 - 1.1.1.25,2.7.1.71,5.4.99.5 0.0002794 47.0
CH2_k127_11723767_2 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000003145 259.0
CH2_k127_11723767_3 Bacterial transferase hexapeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003183 241.0
CH2_k127_11723767_4 PLD-like domain - - - 0.000000000000000000000000000000000000000000000000000000000002361 216.0
CH2_k127_11723767_5 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.0000000000000000000000000000000008997 134.0
CH2_k127_11723767_6 N-6 DNA Methylase - - - 0.000000000000000000000000000000002903 129.0
CH2_k127_11723767_7 - - - - 0.00000000000000000000000002677 118.0
CH2_k127_11723767_8 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000004206 109.0
CH2_k127_11723767_9 Secondary thiamine-phosphate synthase enzyme - - - 0.00000000000000000005375 90.0
CH2_k127_11729626_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.859e-267 831.0
CH2_k127_11729626_1 aromatic hydrocarbon degradation K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 459.0
CH2_k127_11729626_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 461.0
CH2_k127_11729626_3 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001733 275.0
CH2_k127_11729626_4 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000001859 123.0
CH2_k127_11757140_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 5.321e-206 656.0
CH2_k127_11757140_1 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001119 241.0
CH2_k127_11757140_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000429 232.0
CH2_k127_11757140_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.0001951 44.0
CH2_k127_11767979_0 Type II restriction enzyme, methylase subunits - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 448.0
CH2_k127_11767979_1 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002294 259.0
CH2_k127_11767979_2 PFAM Gram-negative bacterial tonB protein K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004218 262.0
CH2_k127_11767979_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000003992 126.0
CH2_k127_11767979_4 DNA modification - - - 0.0000000000000005779 83.0
CH2_k127_11769421_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 3.68e-238 747.0
CH2_k127_11769421_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 617.0
CH2_k127_11769421_2 GGDEF domain K07814 - - 0.00000000000000000000000000000001123 131.0
CH2_k127_11769421_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000001501 130.0
CH2_k127_1177415_0 serine threonine protein kinase K12132 - 2.7.11.1 2.795e-247 790.0
CH2_k127_1177415_1 GGDEF domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 376.0
CH2_k127_1177415_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 298.0
CH2_k127_1177415_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000002198 267.0
CH2_k127_1177415_4 PFAM Amino acid-binding ACT K03567 - - 0.000000000000000000000000000000000000000000004552 169.0
CH2_k127_1177415_5 - - - - 0.00000000000000000001772 99.0
CH2_k127_1177415_6 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.000000003675 60.0
CH2_k127_1177415_7 chemotaxis protein K03407 - 2.7.13.3 0.000009879 56.0
CH2_k127_11803471_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1019.0
CH2_k127_11803471_1 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 321.0
CH2_k127_11803471_2 Type I restriction enzyme R protein N terminus (HSDR_N) K07504 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008748 267.0
CH2_k127_11803471_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001125 247.0
CH2_k127_11803471_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000004466 177.0
CH2_k127_11803471_5 - - - - 0.000000000000000000000000031 111.0
CH2_k127_11803471_6 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000004936 102.0
CH2_k127_11803471_7 Adenine specific DNA methylase Mod K00571,K07316,K07319 - 2.1.1.72 0.0000000000000000000000356 100.0
CH2_k127_11821269_0 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 573.0
CH2_k127_11821269_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000001512 160.0
CH2_k127_11822856_0 HPP family K07168 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002247 252.0
CH2_k127_11822856_1 - - - - 0.0000000000000000000000001666 116.0
CH2_k127_11822856_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000807 79.0
CH2_k127_11823910_0 DNA methylase N-4 N-6 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 453.0
CH2_k127_11823910_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000003789 51.0
CH2_k127_11883652_0 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000002076 210.0
CH2_k127_11883652_1 Phage integrase family - - - 0.00000000000000000000000000000000000000000003746 164.0
CH2_k127_11883652_2 Invasion gene expression up-regulator SirB - - - 0.0000000000000000000000000000000003087 135.0
CH2_k127_11883652_3 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000005183 108.0
CH2_k127_11883652_4 sequence-specific DNA binding K07467 - - 0.000000000000001004 79.0
CH2_k127_11900508_0 ABC-type branched-chain amino acid transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 469.0
CH2_k127_11915729_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 1.426e-227 719.0
CH2_k127_11923245_0 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 535.0
CH2_k127_11923245_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 400.0
CH2_k127_11923245_2 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 370.0
CH2_k127_11923245_3 - - - - 0.0000000000000000000001754 101.0
CH2_k127_11923245_4 PFAM WD-40 repeat - - - 0.000000000002266 74.0
CH2_k127_11923245_5 - - - - 0.00000000006319 66.0
CH2_k127_119359_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001106 248.0
CH2_k127_119359_1 Periplasmic binding protein domain - - - 0.000000000003115 70.0
CH2_k127_11963390_0 methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 8.81e-308 958.0
CH2_k127_11971327_0 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000004881 239.0
CH2_k127_11971327_1 PIN domain - - - 0.00000000000000004045 84.0
CH2_k127_11971327_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000009422 74.0
CH2_k127_12023797_0 N-6 DNA Methylase - - - 0.00000000000000000000000000000000000000000002943 163.0
CH2_k127_12069975_0 Protein of unknown function (DUF1538) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001324 257.0
CH2_k127_12069975_1 CBS domain - - - 0.0000000000000000000000000000000000000000000000007954 179.0
CH2_k127_12069975_2 Nitrogen regulatory protein P-II - - - 0.000000000000000000000000000000000000002166 149.0
CH2_k127_12069975_3 PFAM transposase, IS4 family protein - - - 0.00000000000000001782 84.0
CH2_k127_12076835_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 494.0
CH2_k127_12076835_2 cell adhesion K02650 - - 0.00000000000000005165 84.0
CH2_k127_12113933_0 Peptidase M16C associated K06972 - - 3.256e-257 809.0
CH2_k127_12116519_0 2Fe-2S iron-sulfur cluster binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005327 277.0
CH2_k127_12116519_1 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001161 264.0
CH2_k127_12157144_0 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 391.0
CH2_k127_12157144_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 381.0
CH2_k127_12157144_2 PFAM response regulator receiver - - - 0.0000000000000000000000002252 107.0
CH2_k127_12159098_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1080.0
CH2_k127_12159098_1 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 337.0
CH2_k127_12194922_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0046914,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000085 366.0
CH2_k127_12194922_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008194,GO:0008375,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0050511,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.227 0.000000000000000001058 87.0
CH2_k127_12194922_2 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0000000000000007364 80.0
CH2_k127_12207934_0 Transposase IS4 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 302.0
CH2_k127_12207934_1 Competence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001748 230.0
CH2_k127_12207934_2 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000006824 196.0
CH2_k127_12207934_3 cyclic nucleotide binding K10914 - - 0.00000000000000000000000002043 114.0
CH2_k127_12207934_4 Transposase IS200 like - - - 0.00000000000000000000000003875 109.0
CH2_k127_12215517_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 431.0
CH2_k127_12215517_1 KR domain K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 304.0
CH2_k127_12215517_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 306.0
CH2_k127_12215517_3 TonB-dependent Receptor Plug K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 288.0
CH2_k127_12215517_4 Participates in both transcription termination and antitermination K02600 GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000001762 58.0
CH2_k127_12235821_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 352.0
CH2_k127_12235821_1 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000001695 216.0
CH2_k127_12249294_0 PFAM aminotransferase class-III K01845 - 5.4.3.8 4.406e-200 631.0
CH2_k127_12249294_1 Psort location Cytoplasmic, score 8.96 - - - 0.000002515 51.0
CH2_k127_12253623_0 lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000152 259.0
CH2_k127_12253623_1 SPTR Transposase IS4 family - - - 0.0000000000000000000000000000000000000004005 151.0
CH2_k127_12253623_2 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.00000000000000000000000000000000004078 135.0
CH2_k127_12253623_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000236 119.0
CH2_k127_12253623_4 - - - - 0.0000000001587 63.0
CH2_k127_12262178_0 RNB K01147 - 3.1.13.1 1.205e-242 766.0
CH2_k127_12268828_0 ABC transporter C-terminal domain K15738 - - 1.323e-197 628.0
CH2_k127_12268828_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000001204 167.0
CH2_k127_12268828_2 InterPro IPR004919 IPR011089 - - - 0.000000000000000000000000002716 114.0
CH2_k127_12268828_3 ABC transporter K15738 - - 0.0000000000000166 76.0
CH2_k127_12276755_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 569.0
CH2_k127_12276755_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000001336 209.0
CH2_k127_12284646_0 nitrous oxide reductase K00376 - 1.7.2.4 0.0 1197.0
CH2_k127_12284646_1 Pfam cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 305.0
CH2_k127_12284646_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002109 287.0
CH2_k127_12284646_3 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000001926 150.0
CH2_k127_12284646_4 - - - - 0.0000000000000000000000000003017 120.0
CH2_k127_12284646_5 Adenine specific DNA methylase Mod K00571,K07316,K07319 - 2.1.1.72 0.00000000000000000000000205 103.0
CH2_k127_12284646_6 EF-hand, calcium binding motif - - - 0.000000000000002284 84.0
CH2_k127_12284646_7 Hemerythrin HHE cation binding domain - - - 0.000000000000004443 81.0
CH2_k127_12294105_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 345.0
CH2_k127_12294105_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000138 268.0
CH2_k127_12294105_2 Ferredoxin, 2Fe-2S type, ISC system K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.0000000000000000000000000000000000000000000000000005089 185.0
CH2_k127_12294105_3 NUDIX domain - - - 0.000000000000000000000000000000007399 132.0
CH2_k127_1230162_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 7.448e-214 678.0
CH2_k127_1230162_1 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 361.0
CH2_k127_1230162_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.000000000000000000000000000000000000003663 148.0
CH2_k127_1230162_3 helicase - - - 0.000000000000004682 79.0
CH2_k127_12302385_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.513e-216 680.0
CH2_k127_12302385_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008106 575.0
CH2_k127_12302385_2 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 458.0
CH2_k127_12302385_3 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 342.0
CH2_k127_12302385_4 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002378 237.0
CH2_k127_12302385_5 Protein of unknown function (DUF3782) - - - 0.00000000000000000000000000000000000000000000000000000002317 205.0
CH2_k127_12302385_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000003963 156.0
CH2_k127_12325590_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 476.0
CH2_k127_12325590_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 436.0
CH2_k127_12325590_2 NACHT domain - - - 0.00005601 54.0
CH2_k127_12331454_0 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 340.0
CH2_k127_12331454_1 V-type proton ATPase subunit E K02121 - - 0.0000000000000000000000000000000000000000000537 168.0
CH2_k127_12367314_0 Glycosyl Transferase K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 597.0
CH2_k127_12367314_1 Histidine kinase A domain protein K07678 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 407.0
CH2_k127_12367314_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 321.0
CH2_k127_12367314_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 294.0
CH2_k127_12367314_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000001455 233.0
CH2_k127_12367314_5 glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000186 167.0
CH2_k127_12370176_0 COG1530 Ribonucleases G and E K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 567.0
CH2_k127_12370176_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007467 229.0
CH2_k127_12370176_2 Protein tyrosine kinase - - - 0.000000000000000000000000000000137 127.0
CH2_k127_12370176_3 With ThiF, ThiG, and ThiO catalyzes the formation of the thiazole moiety of thiamine pyrophosphate K03154 - - 0.0000000000000001153 81.0
CH2_k127_12370176_4 PFAM WD domain, G-beta repeat - - - 0.0000000007448 61.0
CH2_k127_12387577_0 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004174 278.0
CH2_k127_12387577_1 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000002936 207.0
CH2_k127_12404511_0 Phage shock protein A K03969 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000009173 251.0
CH2_k127_12404511_1 - - - - 0.0000000000000000000000000000000000000000000001786 169.0
CH2_k127_12417817_0 DNA modification K07317 - 2.1.1.72 5.855e-306 969.0
CH2_k127_12417817_1 Putative exonuclease SbcCD, C subunit K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 467.0
CH2_k127_12417817_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 419.0
CH2_k127_12417817_3 3D domain protein - - - 0.000000000000000000000000000000008945 136.0
CH2_k127_12466166_0 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 7.6e-286 887.0
CH2_k127_12466166_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 396.0
CH2_k127_12466166_2 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000965 165.0
CH2_k127_12466166_3 protein homooligomerization - - - 0.000000000000000000000000000000000000008246 153.0
CH2_k127_12466166_4 Transposase DDE domain - - - 0.00000000000000000000001158 102.0
CH2_k127_12497338_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 362.0
CH2_k127_12497338_1 Type II secretory pathway, component PulD K02453 - - 0.00000000000000000000000000000000000000000000000000000001273 207.0
CH2_k127_12517417_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 285.0
CH2_k127_12517417_1 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001086 250.0
CH2_k127_12517417_2 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000006017 209.0
CH2_k127_12532170_0 B-1 B cell differentiation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 433.0
CH2_k127_12555458_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 9.252e-261 833.0
CH2_k127_12555458_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000003389 159.0
CH2_k127_12555458_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000009141 154.0
CH2_k127_12555458_3 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000005791 139.0
CH2_k127_1256605_0 Specifically methylates the guanosine in position 1516 of 16S rRNA K15984 - 2.1.1.242 0.0000000000000000000000000000000000000000000000000000000000000000000001416 248.0
CH2_k127_1256605_1 DNA methylase - - - 0.000000000000000000000000000000000000000000000000002692 200.0
CH2_k127_1256605_2 17 kDa surface antigen K06077 - - 0.00000000000000000000000000000000000001271 149.0
CH2_k127_12570353_0 Large extracellular alpha-helical protein K06894 - - 7.668e-318 992.0
CH2_k127_12609560_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 471.0
CH2_k127_12609560_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001636 283.0
CH2_k127_12609560_2 small GTP-binding protein K06945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007168 244.0
CH2_k127_12609560_3 Roadblock LC7 family protein K07131 - - 0.000000000000000000000000000000000000000000000000000000001261 201.0
CH2_k127_12609560_4 pfam abc K02003 - - 0.000000000000000000000000000000000000000000000004686 177.0
CH2_k127_12609560_5 C-type lectin (CTL) or carbohydrate-recognition domain (CRD) - - - 0.00000000000000000000313 104.0
CH2_k127_12609560_6 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000003329 65.0
CH2_k127_12625846_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009563 501.0
CH2_k127_12625846_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 494.0
CH2_k127_12625846_2 DNA methylase - - - 0.0000000191 60.0
CH2_k127_12636542_0 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 342.0
CH2_k127_12636542_1 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.000000000000000000000000000000000000000000002318 171.0
CH2_k127_12636542_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000009793 48.0
CH2_k127_12640993_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007727 457.0
CH2_k127_12640993_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 319.0
CH2_k127_12640993_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 281.0
CH2_k127_12640993_3 - - - - 0.00000000000000000000000000000000000000000000000000003082 204.0
CH2_k127_12640993_4 Part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000000000001518 167.0
CH2_k127_12640993_5 Domain of unknown function DUF29 - - - 0.0000000000000000000000000000000000000000006356 161.0
CH2_k127_12640993_6 - - - - 0.000000000000000000000004404 105.0
CH2_k127_12640993_7 - - - - 0.000000000000000000000004983 107.0
CH2_k127_12640993_8 Family of unknown function (DUF5329) - - - 0.000000000000000000004698 97.0
CH2_k127_12640993_9 Zinc finger, swim domain protein - - - 0.000000000000001626 83.0
CH2_k127_12663670_0 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 428.0
CH2_k127_12663670_1 protein-glutamate methylesterase K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000004233 250.0
CH2_k127_12663670_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000003935 217.0
CH2_k127_12686898_0 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 2.865e-196 621.0
CH2_k127_12686898_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 598.0
CH2_k127_12686898_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 567.0
CH2_k127_12686898_3 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 504.0
CH2_k127_12686898_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009974 371.0
CH2_k127_12686898_5 CfrBI restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 371.0
CH2_k127_12686898_6 PFAM Positive regulator of sigma(E), RseC MucC K03803 - - 0.00000000000000000000000000000003469 131.0
CH2_k127_12686898_7 Glutaredoxin-like domain (DUF836) K00384 - 1.8.1.9 0.00000000000000000000005509 100.0
CH2_k127_12686898_8 PFAM metal-dependent phosphohydrolase HD sub domain K07814 - - 0.0000008032 55.0
CH2_k127_12692530_0 Methyl-accepting chemotaxis protein (MCP) signaling domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 550.0
CH2_k127_12692530_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 338.0
CH2_k127_12692530_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 344.0
CH2_k127_12692530_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 323.0
CH2_k127_12692530_4 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 291.0
CH2_k127_12692530_5 Response regulator receiver K02658 - - 0.0000000000000000000000000000000000000000000000000000000000000008197 220.0
CH2_k127_12692530_6 CheW-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000004366 221.0
CH2_k127_12692530_7 Adenine specific DNA methylase Mod - - - 0.000000000000000000000000000000000000000000000006229 175.0
CH2_k127_12729093_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 4.365e-279 873.0
CH2_k127_12729093_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 327.0
CH2_k127_12729093_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000008587 123.0
CH2_k127_12729093_3 Tetratricopeptide repeat - - - 0.000000000000000000001891 99.0
CH2_k127_12780459_0 ABC transporter K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 332.0
CH2_k127_12780459_1 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 320.0
CH2_k127_12780459_2 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000001654 64.0
CH2_k127_12809526_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 5.885e-206 647.0
CH2_k127_12925343_0 YcjX-like family, DUF463 K06918 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 499.0
CH2_k127_12925343_1 Domain of unknown function (DUF697) K08990 - - 0.000000000000000000000000000000000000000000000000000002694 205.0
CH2_k127_12925343_2 membrane transporter protein K07090,K11312 - - 0.000000000000000000000000000000000000000000000000001761 184.0
CH2_k127_1293594_0 PFAM Type II IV secretion system protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 582.0
CH2_k127_1293594_1 twitching motility protein PilT K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 546.0
CH2_k127_1293594_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 411.0
CH2_k127_1293594_3 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002549 267.0
CH2_k127_1293594_4 SMART zinc finger, CDGSH-type domain protein - - - 0.00000000000000000000000000003888 119.0
CH2_k127_12937076_0 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 514.0
CH2_k127_12937076_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 495.0
CH2_k127_12937076_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 347.0
CH2_k127_12937076_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000004458 233.0
CH2_k127_12937076_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000007564 225.0
CH2_k127_1297781_0 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 342.0
CH2_k127_12979298_0 PFAM AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000000001203 235.0
CH2_k127_12980294_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 GO:0000715,GO:0000716,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006283,GO:0006289,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0019899,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0043175,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051276,GO:0051716,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 6.168e-310 969.0
CH2_k127_12980294_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000001465 199.0
CH2_k127_13032627_0 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 338.0
CH2_k127_13032627_1 type II secretion system protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 311.0
CH2_k127_13032627_2 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000001187 143.0
CH2_k127_1304452_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 431.0
CH2_k127_1304452_1 transposase and inactivated derivatives, IS30 family K07482 - - 0.00000000000000000000000002365 110.0
CH2_k127_1304452_2 transposase and inactivated derivatives, IS30 family K07482 - - 0.000000000000000000000004797 105.0
CH2_k127_1304452_3 NUDIX domain K01515 - 3.6.1.13 0.00000000000000004153 81.0
CH2_k127_1304452_4 Integrase core domain - - - 0.000001328 51.0
CH2_k127_1307508_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 439.0
CH2_k127_1307508_1 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.0000000000000003292 78.0
CH2_k127_1307508_2 to AA sequence GI 30249526 - - - 0.00000001553 57.0
CH2_k127_131535_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 392.0
CH2_k127_131535_1 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000143 257.0
CH2_k127_1335228_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 7.119e-255 792.0
CH2_k127_1335228_1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 1.115e-209 671.0
CH2_k127_1396573_0 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 338.0
CH2_k127_1396573_1 TonB dependent receptor K02014,K16089 - - 0.00000000000000000000000000000000000000000000000000000000000000000002883 257.0
CH2_k127_1396573_2 - - - - 0.000000000000000000000000000006561 126.0
CH2_k127_1396573_3 IS30 family K07482 - - 0.0004026 45.0
CH2_k127_1407385_0 TPR repeat - - - 0.00000000000000000000000000000000000000000427 160.0
CH2_k127_1407385_1 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.0000000000000000000000000002812 116.0
CH2_k127_1407385_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000005239 68.0
CH2_k127_1442726_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.743e-264 828.0
CH2_k127_1442726_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0016020,GO:0016021,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0031224,GO:0031226,GO:0034641,GO:0036094,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051186,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072524,GO:0097159,GO:1901265,GO:1901360,GO:1901363,GO:1901564 1.6.1.2 1.216e-246 770.0
CH2_k127_1442726_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 3.599e-217 681.0
CH2_k127_1442726_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 568.0
CH2_k127_1442726_4 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 361.0
CH2_k127_1442726_5 PFAM heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000004737 147.0
CH2_k127_1442726_6 to AA sequence GI 30249526 - - - 0.0000000008418 59.0
CH2_k127_1485006_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.033e-204 661.0
CH2_k127_1485006_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 523.0
CH2_k127_1485006_2 Polyphosphate AMP phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 343.0
CH2_k127_1485006_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000003735 149.0
CH2_k127_1546412_0 ATP:ADP antiporter activity - - - 1.141e-239 767.0
CH2_k127_1546412_1 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000002961 227.0
CH2_k127_1609915_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008023 255.0
CH2_k127_1609915_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000004762 137.0
CH2_k127_1609915_2 proteolysis - - - 0.00002568 49.0
CH2_k127_170419_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 GO:0001676,GO:0003674,GO:0003824,GO:0004467,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006635,GO:0006637,GO:0006644,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009150,GO:0009259,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009898,GO:0009987,GO:0015645,GO:0016020,GO:0016042,GO:0016054,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0019395,GO:0019637,GO:0019693,GO:0019752,GO:0030258,GO:0031406,GO:0032787,GO:0033293,GO:0033865,GO:0033875,GO:0034032,GO:0034440,GO:0034641,GO:0035383,GO:0036041,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046395,GO:0046483,GO:0050896,GO:0051186,GO:0055086,GO:0055114,GO:0070538,GO:0071704,GO:0071944,GO:0072329,GO:0072521,GO:0090407,GO:0098552,GO:0098562,GO:1901135,GO:1901360,GO:1901564,GO:1901575,GO:1901576 6.2.1.3 8.709e-220 694.0
CH2_k127_170419_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 477.0
CH2_k127_170419_2 Quinol dehydrogenase K02574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 467.0
CH2_k127_170419_3 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 406.0
CH2_k127_170419_4 4Fe-4S binding domain K02573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007752 269.0
CH2_k127_1725699_0 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 520.0
CH2_k127_1725699_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 291.0
CH2_k127_1725699_2 Nitrite and sulphite reductase 4Fe-4S K02572 - - 0.000000000000000000000000000000000000000000000000000005125 196.0
CH2_k127_1725699_3 PFAM WD domain, G-beta repeat - - - 0.000000000000000000000000000000004603 132.0
CH2_k127_1735894_0 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000001057 179.0
CH2_k127_1735894_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000002691 163.0
CH2_k127_1735894_2 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000001088 117.0
CH2_k127_1735894_3 Chromate Ion Transporter K07240 - - 0.000000006705 57.0
CH2_k127_1807376_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 8.159e-265 820.0
CH2_k127_1807376_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006879 254.0
CH2_k127_1807376_2 Plasmid pRiA4b ORF-3-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000001956 217.0
CH2_k127_1807376_3 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000008583 124.0
CH2_k127_1807376_4 General secretion pathway protein I K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000000005398 102.0
CH2_k127_1807376_5 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000014 110.0
CH2_k127_1807376_6 - - - - 0.000000000000009297 82.0
CH2_k127_183648_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000001878 241.0
CH2_k127_183648_1 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000007659 145.0
CH2_k127_183648_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000002405 139.0
CH2_k127_183648_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000296 137.0
CH2_k127_1852963_1 LysM domain K01448,K08307,K19223,K22278 - 3.5.1.104,3.5.1.28 0.0000000000000000000000000000000000000003779 161.0
CH2_k127_1852963_2 - - - - 0.000000000000000000000000000003022 126.0
CH2_k127_1852963_3 LysM domain K01448,K08307,K19223,K22278 - 3.5.1.104,3.5.1.28 0.00000000000000000008222 98.0
CH2_k127_1852963_4 AAA-like domain - - - 0.0000000000000000004899 93.0
CH2_k127_1852963_5 Peptidase family M23 K06194 - - 0.000000004153 61.0
CH2_k127_1878767_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009126 490.0
CH2_k127_1878767_1 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001054 280.0
CH2_k127_1878767_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000009036 232.0
CH2_k127_1878767_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000009715 85.0
CH2_k127_1900618_0 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 516.0
CH2_k127_1900618_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 505.0
CH2_k127_1900618_2 short-chain dehydrogenase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 339.0
CH2_k127_1911531_0 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000004183 246.0
CH2_k127_1911531_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000002 102.0
CH2_k127_1911766_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 602.0
CH2_k127_1911766_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000006878 244.0
CH2_k127_1911766_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000002417 115.0
CH2_k127_1911766_3 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.0000000000000000000002902 97.0
CH2_k127_1951286_0 response regulator receiver - - - 7.204e-210 660.0
CH2_k127_1951286_1 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 601.0
CH2_k127_1951286_10 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000002542 142.0
CH2_k127_1951286_2 Zn-dependent protease with chaperone function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 465.0
CH2_k127_1951286_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 333.0
CH2_k127_1951286_4 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 295.0
CH2_k127_1951286_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000356 258.0
CH2_k127_1951286_6 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003363 248.0
CH2_k127_1951286_7 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000003932 208.0
CH2_k127_1951286_8 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.000000000000000000000000000000000000000000002182 173.0
CH2_k127_1951286_9 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000000000000001108 166.0
CH2_k127_1956379_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1293.0
CH2_k127_201907_0 COG0618 Exopolyphosphatase-related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 497.0
CH2_k127_201907_1 Putative DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001794 237.0
CH2_k127_201907_2 Lytic transglycosylase catalytic K08307 - - 0.000000000000000703 83.0
CH2_k127_2040438_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 1.062e-225 706.0
CH2_k127_2051559_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 4.39e-290 900.0
CH2_k127_2051559_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.577e-254 793.0
CH2_k127_2051559_2 PFAM Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001232 241.0
CH2_k127_2051559_3 Domain of unknown function DUF29 - - - 0.000000000000000000000000000000000000000000000000000000007046 201.0
CH2_k127_2051559_4 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000001695 118.0
CH2_k127_2051559_5 Predicted integral membrane protein (DUF2282) - - - 0.0000000000000000000000001656 109.0
CH2_k127_2051559_6 Acetolactate synthase small K01653 - 2.2.1.6 0.0000000000000002161 78.0
CH2_k127_2089378_0 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000000000000000000000000000855 221.0
CH2_k127_2089378_1 4Fe-4S binding domain K02574 - - 0.000000000000000000000000000000000000000000000000000000000000004397 220.0
CH2_k127_2089378_2 DNA methylase - - - 0.0000000000000000000000000000000000000000000000000000000000002486 213.0
CH2_k127_2089378_3 - - - - 0.000000000000000000000009769 102.0
CH2_k127_2092041_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 5.244e-213 668.0
CH2_k127_2092041_2 Protein of unknown function (DUF2892) - - - 0.000000000000004616 76.0
CH2_k127_2092041_3 PFAM Na Picotransporter K03324 - - 0.000000001775 61.0
CH2_k127_2093743_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.735e-307 957.0
CH2_k127_2093743_1 Domain of unknown function DUF302 - - - 0.000004679 56.0
CH2_k127_2093743_2 PFAM secretion protein HlyD - - - 0.0002559 44.0
CH2_k127_2099840_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 570.0
CH2_k127_2100885_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 524.0
CH2_k127_2100885_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 470.0
CH2_k127_2100885_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000001368 129.0
CH2_k127_2101144_0 type IV restriction endonuclease K07504 - - 0.000000000000000000000000000000000000004172 159.0
CH2_k127_2101144_1 acr, cog1565 - - - 0.0000002708 61.0
CH2_k127_2103213_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 514.0
CH2_k127_2103213_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 450.0
CH2_k127_2103213_2 COG0859 ADP-heptose LPS heptosyltransferase K02843 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 364.0
CH2_k127_2193671_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 479.0
CH2_k127_2242272_0 FAD binding domain K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 1.297e-223 703.0
CH2_k127_2242272_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009524 588.0
CH2_k127_2242272_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 290.0
CH2_k127_2258266_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 - 6.3.1.5,6.3.5.1 0.0 1014.0
CH2_k127_2258266_1 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005466 261.0
CH2_k127_2258266_2 PFAM GGDEF domain containing protein K21020 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000115 206.0
CH2_k127_2258266_3 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000000000008403 190.0
CH2_k127_2258266_4 aminopeptidase - - - 0.0000000000000000000000000000000000000000082 155.0
CH2_k127_2258266_5 - - - - 0.0000000000002129 70.0
CH2_k127_2277499_0 Fumarate reductase flavoprotein C-term - - - 3.508e-278 865.0
CH2_k127_2277499_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007568 551.0
CH2_k127_2277499_2 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 349.0
CH2_k127_2277499_3 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00246 - - 0.0000000000000000000000000002232 118.0
CH2_k127_2277499_4 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00247 - - 0.0000000000000000000000001097 109.0
CH2_k127_2277499_5 HD domain - - - 0.000006674 50.0
CH2_k127_228436_0 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000001337 193.0
CH2_k127_228436_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000003707 194.0
CH2_k127_228436_3 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000001237 172.0
CH2_k127_228436_4 HEPN domain - - - 0.0000000000000000000000000000000001259 137.0
CH2_k127_2306225_0 DUF1704 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 577.0
CH2_k127_2306225_1 Prokaryotic glutathione synthetase, N-terminal domain K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 496.0
CH2_k127_2306225_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000002786 182.0
CH2_k127_2317379_0 tellurium resistance protein K05792 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 527.0
CH2_k127_2317379_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 500.0
CH2_k127_2317379_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 287.0
CH2_k127_2317379_3 Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - 0.00000000000000000000000000000000000000002349 160.0
CH2_k127_2342858_0 polyphosphate kinase 2 K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 290.0
CH2_k127_2342858_1 SEC-C Motif Domain Protein - - - 0.00000000000000000000000000000000000000000000000000000008649 205.0
CH2_k127_2342858_2 DDE superfamily endonuclease - - - 0.000000000004609 66.0
CH2_k127_2359161_0 ATP synthase (C/AC39) subunit K02119 - - 0.00000000000000000000000000000000000000000000000000000000000003107 226.0
CH2_k127_2359161_1 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17229 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.8.2.3 0.0000000000000000000000000000000000000000000000000000005314 197.0
CH2_k127_2359161_2 Cytochrome c class I - - - 0.00000000000000000000000000000000000000000000000008551 184.0
CH2_k127_2359161_3 - - - - 0.0000000000002516 74.0
CH2_k127_2369318_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 587.0
CH2_k127_2369318_1 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 564.0
CH2_k127_2369318_2 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 318.0
CH2_k127_2369318_3 PFAM Rhodanese-like - - - 0.000000000000000000000000000000000000000000000000000001002 196.0
CH2_k127_2369318_4 Domain of unknown function DUF29 - - - 0.00000000000000000000000000000000000003135 148.0
CH2_k127_2369318_5 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000007631 139.0
CH2_k127_2389472_0 TIGRFAM general secretion pathway protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 495.0
CH2_k127_2389472_1 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000002666 184.0
CH2_k127_2414433_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 381.0
CH2_k127_2414433_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005303 322.0
CH2_k127_2422184_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K13924 - 2.1.1.80,3.1.1.61 9.378e-206 668.0
CH2_k127_2422184_1 4Fe-4S binding domain K02573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 307.0
CH2_k127_2422184_2 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001197 280.0
CH2_k127_2422184_3 Invasion gene expression up-regulator SirB - - - 0.0000000000000000000000000000001372 126.0
CH2_k127_2428408_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 399.0
CH2_k127_2428408_1 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002077 298.0
CH2_k127_2428408_2 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000003374 106.0
CH2_k127_2428408_3 polyphosphate kinase activity K22468 - 2.7.4.1 0.000000008217 56.0
CH2_k127_2431178_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1053.0
CH2_k127_2431178_1 Pfam Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 370.0
CH2_k127_2474493_0 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000009259 202.0
CH2_k127_2474493_1 Transposase DDE domain - - - 0.000000000000000000000002283 105.0
CH2_k127_2489961_0 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 366.0
CH2_k127_2539369_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004187 271.0
CH2_k127_2591305_0 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 364.0
CH2_k127_2591305_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 287.0
CH2_k127_2591305_2 NosL - - - 0.00000000000000000000000000000000000004754 147.0
CH2_k127_2591305_3 Adenine specific DNA methylase Mod - - - 0.000000000000000000000005786 105.0
CH2_k127_2604641_0 conserved protein UCP016719 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 481.0
CH2_k127_2604641_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 362.0
CH2_k127_2604641_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000001209 159.0
CH2_k127_2604641_3 regulation of ryanodine-sensitive calcium-release channel activity - - - 0.000000000000000000000000005485 115.0
CH2_k127_2604641_4 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000004607 66.0
CH2_k127_2607778_0 Na+ dependent nucleoside transporter N-terminus K03317 GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007169 438.0
CH2_k127_2607778_1 - - - - 0.00000000000000002037 86.0
CH2_k127_2623468_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.125e-243 760.0
CH2_k127_2623468_1 Adenine specific DNA methylase Mod K00571,K07316,K07319 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 550.0
CH2_k127_2623468_2 - - - - 0.0000000000000000000000000002686 117.0
CH2_k127_2623468_3 Transcriptional regulator - - - 0.0004458 49.0
CH2_k127_2638435_0 (Lipo)protein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000591 256.0
CH2_k127_2638435_1 Domain of unknown function DUF29 - - - 0.000000000000000000000000000000000000001045 151.0
CH2_k127_2643104_0 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004269 277.0
CH2_k127_2643104_1 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006427 244.0
CH2_k127_2643104_2 Nacht domain - - - 0.00000000000000000000000000000000000000000000000000000001731 201.0
CH2_k127_2643104_3 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.0000000000000006732 80.0
CH2_k127_2665576_0 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000006628 205.0
CH2_k127_2665576_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000004522 107.0
CH2_k127_2671896_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 387.0
CH2_k127_2760702_0 heptosyltransferase K02849 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:0071967,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 428.0
CH2_k127_2760702_1 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 344.0
CH2_k127_2760702_2 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007591 261.0
CH2_k127_2760702_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0000000000000000000000000000000000000000000000000000055 192.0
CH2_k127_2760702_4 PIN domain - - - 0.000000000000000003109 89.0
CH2_k127_2801302_0 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 359.0
CH2_k127_2801302_1 - - - - 0.00000000000000000000000000000000000002546 149.0
CH2_k127_2837631_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 594.0
CH2_k127_2850866_0 Sulfatase K03760 - 2.7.8.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007843 595.0
CH2_k127_2850866_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 342.0
CH2_k127_2868128_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 617.0
CH2_k127_2868128_1 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.0000000000000000000000000000000000000007332 168.0
CH2_k127_2874422_0 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 294.0
CH2_k127_2874422_1 Pentapeptide repeats (8 copies) - - - 0.000000000000000000000000000000000000000000000000007509 198.0
CH2_k127_2936760_0 Histidine kinase - - - 1.58e-314 1005.0
CH2_k127_2944258_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 382.0
CH2_k127_3010967_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 590.0
CH2_k127_3010967_1 InsA N-terminal domain - - - 0.00001425 47.0
CH2_k127_3051937_0 Histidine kinase A domain protein K07678 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 414.0
CH2_k127_3051937_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 347.0
CH2_k127_3051937_2 phosphatase activity - - - 0.0000000000000000000001574 106.0
CH2_k127_3065913_0 Lytic murein transglycosylase B K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 364.0
CH2_k127_3065913_1 nuclear chromosome segregation K01153,K13924,K15492 - 2.1.1.80,3.1.1.61,3.1.21.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 310.0
CH2_k127_3065913_2 peptidoglycan binding K03642 - - 0.00000000000000004855 86.0
CH2_k127_3068169_0 ABC-type oligopeptide transport system, periplasmic component K02035,K13893 GO:0005575,GO:0005623,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042493,GO:0042597,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 2.382e-203 646.0
CH2_k127_3068169_1 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 495.0
CH2_k127_3109956_0 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 320.0
CH2_k127_3109956_1 PFAM Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 312.0
CH2_k127_3121980_0 type III K01156 - 3.1.21.5 0.0 1065.0
CH2_k127_3121980_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 575.0
CH2_k127_3121980_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 501.0
CH2_k127_3121980_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 287.0
CH2_k127_3133428_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 3.561e-210 659.0
CH2_k127_3133428_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 385.0
CH2_k127_3133428_2 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 302.0
CH2_k127_3133428_3 family UPF0027 K14415 - 6.5.1.3 0.0000000000000000000000000000000004634 136.0
CH2_k127_3133428_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000001097 105.0
CH2_k127_3171427_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 572.0
CH2_k127_3171427_1 Oxidoreductase K19813 - 1.1.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 297.0
CH2_k127_3213612_0 ATP-citrate synthase beta chain protein K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006084,GO:0006085,GO:0006139,GO:0006163,GO:0006164,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 1.054e-231 732.0
CH2_k127_3213612_1 ATP citrate synthase activity K01648 GO:0000166,GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003878,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0006066,GO:0006082,GO:0006084,GO:0006085,GO:0006101,GO:0006107,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009893,GO:0009987,GO:0012505,GO:0015936,GO:0016020,GO:0016053,GO:0016125,GO:0016126,GO:0016192,GO:0016740,GO:0016746,GO:0016999,GO:0017076,GO:0017144,GO:0018130,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030141,GO:0030554,GO:0031323,GO:0031325,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032940,GO:0032991,GO:0033500,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0034774,GO:0035337,GO:0035383,GO:0035384,GO:0035578,GO:0035639,GO:0036094,GO:0036230,GO:0042119,GO:0042582,GO:0042592,GO:0042593,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046165,GO:0046390,GO:0046394,GO:0046483,GO:0046903,GO:0046912,GO:0046949,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0055086,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:0101002,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901568,GO:1901570,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653,GO:1904813 2.3.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 430.0
CH2_k127_3232373_0 V-type ATPase 116kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 511.0
CH2_k127_3232373_1 Ras of Complex, Roc, domain of DAPkinase K06883 - - 0.0000003356 53.0
CH2_k127_3258594_0 O-antigen ligase like membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000578 287.0
CH2_k127_3258594_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000007703 111.0
CH2_k127_3261450_0 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.00000000000000000000000000000000000000000000000000000000002605 213.0
CH2_k127_3261450_1 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000001924 115.0
CH2_k127_3313341_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1208.0
CH2_k127_3313341_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.585e-210 660.0
CH2_k127_3313341_10 ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - 0.00000000000000000000000004267 125.0
CH2_k127_3313341_11 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0034645,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0050896,GO:0051103,GO:0051287,GO:0051716,GO:0070403,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1901576 6.5.1.2 0.00000000000000003081 82.0
CH2_k127_3313341_12 Transcription factor zinc-finger K09981 - - 0.000000000009154 69.0
CH2_k127_3313341_13 - - - - 0.000001235 51.0
CH2_k127_3313341_14 - - - - 0.00003364 46.0
CH2_k127_3313341_15 - - - - 0.0004362 43.0
CH2_k127_3313341_2 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 544.0
CH2_k127_3313341_3 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 364.0
CH2_k127_3313341_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 327.0
CH2_k127_3313341_5 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 329.0
CH2_k127_3313341_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 323.0
CH2_k127_3313341_7 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000000000000000000004101 205.0
CH2_k127_3313341_8 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000001796 148.0
CH2_k127_3313341_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000003488 112.0
CH2_k127_3329609_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.511e-266 827.0
CH2_k127_3329609_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 289.0
CH2_k127_3329609_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001754 246.0
CH2_k127_3329609_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000001129 216.0
CH2_k127_3333381_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 360.0
CH2_k127_3333381_1 COG0840 Methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000009708 139.0
CH2_k127_3333381_2 - - - - 0.00000000000000009559 92.0
CH2_k127_3340371_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 449.0
CH2_k127_3344717_0 PFAM Transglutaminase-like superfamily K22452 - 2.3.2.13 3.042e-194 626.0
CH2_k127_3344717_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 506.0
CH2_k127_3344717_2 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 377.0
CH2_k127_3344717_3 PFAM Archaeal ATPase - - - 0.0000000000000000000000000776 118.0
CH2_k127_3412040_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 4.192e-284 880.0
CH2_k127_3412040_1 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 443.0
CH2_k127_3412040_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000002525 268.0
CH2_k127_3412040_3 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.000000000000000000000000000000000000000000000000000000000000002464 224.0
CH2_k127_3412040_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000001085 186.0
CH2_k127_3412040_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000005198 147.0
CH2_k127_3419550_0 major facilitator superfamily K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 388.0
CH2_k127_3450489_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 509.0
CH2_k127_3450489_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 412.0
CH2_k127_3465703_0 GMC oxidoreductase K03333 - 1.1.3.6 1.99e-203 647.0
CH2_k127_3465703_1 Transposase - - - 0.000000000006809 69.0
CH2_k127_3505768_0 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 5.237e-270 857.0
CH2_k127_3505768_1 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 537.0
CH2_k127_3505768_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 398.0
CH2_k127_3505768_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000005613 201.0
CH2_k127_3505768_4 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000004001 159.0
CH2_k127_3522961_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 497.0
CH2_k127_3522961_1 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 299.0
CH2_k127_3522961_2 PFAM PilZ domain K02676 - - 0.0000000000000000000000000000000000000000003118 160.0
CH2_k127_3531961_0 PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain K02660 - - 1.898e-262 827.0
CH2_k127_3531961_1 Histidine kinase - - - 1.47e-213 676.0
CH2_k127_3531961_2 glutamate--cysteine ligase K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 541.0
CH2_k127_3531961_3 PFAM Response regulator receiver domain K02657 - - 0.00000000000000000000000000000000000000000000000000000000000000000002439 234.0
CH2_k127_3531961_4 Type IV pili signal transduction protein PilI K02659 - - 0.000000000000000000000000000000000000000000000000000000000000003479 222.0
CH2_k127_3531961_5 PFAM Response regulator receiver domain K02658 - - 0.00000000000000000000000000000000000000000000000000000000000001448 216.0
CH2_k127_3531961_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02487,K06596 - - 0.000000000000000000000000000000000000000000000000000000000002198 221.0
CH2_k127_3531961_7 Belongs to the N(4) N(6)-methyltransferase family K01154,K03933,K07316 - 2.1.1.72,3.1.21.3 0.0000000000000000000000002938 114.0
CH2_k127_3544704_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 4.326e-264 820.0
CH2_k127_3544704_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 336.0
CH2_k127_3559563_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 329.0
CH2_k127_3588861_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 8.661e-307 967.0
CH2_k127_3588861_1 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000001537 177.0
CH2_k127_3588861_2 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000001108 169.0
CH2_k127_3588861_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000002556 126.0
CH2_k127_3588861_4 - - - - 0.0000000000000000000000000004659 116.0
CH2_k127_3588861_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000005092 116.0
CH2_k127_3647799_0 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 610.0
CH2_k127_3647799_1 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000009087 199.0
CH2_k127_3647799_2 Protein tyrosine phosphatase - - - 0.00000000008998 67.0
CH2_k127_3660528_0 AAA domain K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 302.0
CH2_k127_3739094_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 483.0
CH2_k127_3739094_1 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001161 279.0
CH2_k127_3739094_2 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000001471 108.0
CH2_k127_3739094_3 methyl-accepting chemotaxis protein K03406 - - 0.000003847 53.0
CH2_k127_3739094_4 transmembrane signaling receptor activity - - - 0.000005806 53.0
CH2_k127_3766563_0 Tetratricopeptide TPR_2 repeat protein - - - 4.398e-197 629.0
CH2_k127_3783275_0 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 426.0
CH2_k127_3783275_1 Ferredoxin-type protein napG of Proteobacteria UniRef RepID K02573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002107 243.0
CH2_k127_3783555_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 294.0
CH2_k127_3783555_1 lytic transglycosylase activity K03194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 288.0
CH2_k127_3783555_2 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000003573 118.0
CH2_k127_3783555_3 Domain of unknown function (DUF4124) - - - 0.000007411 49.0
CH2_k127_3784203_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 511.0
CH2_k127_3784203_1 Molybdenum cofactor biosynthesis protein MoaE K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000007936 189.0
CH2_k127_3784203_2 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000000004043 94.0
CH2_k127_3788454_0 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000007746 260.0
CH2_k127_3788454_1 hemerythrin-like metal-binding K07216 - - 0.00000000000000000000000000000000000000000000000005379 183.0
CH2_k127_3788454_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000001349 133.0
CH2_k127_3799623_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 382.0
CH2_k127_3803256_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1e-203 646.0
CH2_k127_3803256_1 phosphatidate Cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000001843 93.0
CH2_k127_3803256_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000001225 87.0
CH2_k127_3823405_0 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 297.0
CH2_k127_3823405_1 HD domain K01139 - 2.7.6.5,3.1.7.2 0.000000000000000000000000000000000000000000000000000000000007702 212.0
CH2_k127_3823405_2 protein conserved in bacteria K05527,K09780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000002643 154.0
CH2_k127_3823405_3 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000001764 57.0
CH2_k127_3852870_0 Cytochrome D1 heme domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 457.0
CH2_k127_3852870_1 Crp-like helix-turn-helix domain K21563 - - 0.00000000000000000000000000000000000000000000000002672 186.0
CH2_k127_3852870_2 Pfam Hemerythrin HHE - - - 0.000000000000000000000000000000000000007911 149.0
CH2_k127_3852870_3 Protein of unknown function (DUF420) - - - 0.000000000000000000000000000000000415 135.0
CH2_k127_3852870_4 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000167 128.0
CH2_k127_3852870_5 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000009071 86.0
CH2_k127_3876522_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 4.049e-281 875.0
CH2_k127_3876522_1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 511.0
CH2_k127_3876522_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 379.0
CH2_k127_3876522_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 346.0
CH2_k127_3876522_4 response regulator, receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000001876 213.0
CH2_k127_3876522_5 Preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000000001048 133.0
CH2_k127_3876522_6 Thioredoxin-like - - - 0.00000000000000000000000000001309 124.0
CH2_k127_3876522_7 - - - - 0.00000000000000000000000007811 122.0
CH2_k127_3876522_8 FAD linked oxidase domain protein - - - 0.000000000000000002873 85.0
CH2_k127_3904158_0 ATP-dependent helicase K03578 - 3.6.4.13 0.0 1570.0
CH2_k127_3904158_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 366.0
CH2_k127_3904158_2 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000000000004407 140.0
CH2_k127_3904158_3 - - - - 0.00000000000000000000000000000001502 134.0
CH2_k127_3905619_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 422.0
CH2_k127_3905619_1 - - - - 0.000000000000000000000000000000000000000000000003574 181.0
CH2_k127_3905619_2 - - - - 0.00000000000000000000000000000000002956 139.0
CH2_k127_3905619_3 Clan AA aspartic protease K06985 - - 0.0000000000000000000000000005889 121.0
CH2_k127_3938170_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 493.0
CH2_k127_3952211_0 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.506e-243 759.0
CH2_k127_3952211_1 - - - - 0.00000000000000000000000000000000000000000000000000000000001776 211.0
CH2_k127_3952211_2 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000001678 96.0
CH2_k127_3963550_0 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 609.0
CH2_k127_3966671_0 Type II secretion system K02653 - - 0.0000000000000000000000000000000000000002102 160.0
CH2_k127_3966671_1 Type II secretion system K02653 - - 0.0000000005318 65.0
CH2_k127_3967468_0 reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 3.469e-217 679.0
CH2_k127_3967468_1 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein K11181 - 1.8.99.5 8.951e-206 642.0
CH2_k127_3967468_2 Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 325.0
CH2_k127_3967468_3 TIGRFAM sulfur relay protein TusD DsrE K07235 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0019417,GO:0044237,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000006895 220.0
CH2_k127_3967468_4 Belongs to the DsrF TusC family K07236 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.00000000000000000000000000000000000000000000000000000000000000887 218.0
CH2_k127_3967468_5 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000000003358 188.0
CH2_k127_3967468_6 sulfur relay protein TusB DsrH K07237 - - 0.0000000000000000000000000000001704 125.0
CH2_k127_4006603_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1009.0
CH2_k127_4007114_0 glycosyl transferase family 2 K20444 - - 3.308e-289 903.0
CH2_k127_4007114_1 MGS-like domain - - - 2.121e-202 639.0
CH2_k127_4007114_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004042 278.0
CH2_k127_4007114_3 PFAM transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000008565 177.0
CH2_k127_4036216_0 Histidine kinase A domain protein K07678 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 368.0
CH2_k127_4036216_1 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000006127 202.0
CH2_k127_4073485_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1436.0
CH2_k127_4084550_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.741e-225 704.0
CH2_k127_4084550_1 Sulfate transporter antisigma-factor antagonist STAS - - - 1.055e-221 700.0
CH2_k127_4084550_2 Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000000000000000000000000000000000000000000000239 196.0
CH2_k127_4084550_3 Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000129 59.0
CH2_k127_4115245_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 479.0
CH2_k127_4115245_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 427.0
CH2_k127_4115245_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 403.0
CH2_k127_4115245_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 349.0
CH2_k127_4115245_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000231 240.0
CH2_k127_4115245_5 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000009164 142.0
CH2_k127_4115245_6 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000005784 139.0
CH2_k127_4115245_7 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000000000175 94.0
CH2_k127_4115245_8 - - - - 0.00001286 48.0
CH2_k127_4174987_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 332.0
CH2_k127_4186169_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 6.829e-233 731.0
CH2_k127_4251837_0 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 431.0
CH2_k127_4251837_1 AAA ATPase domain - - - 0.0000000000000000000000000000000847 133.0
CH2_k127_4259647_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07646 - 2.7.13.3 4.6e-247 781.0
CH2_k127_4259647_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 353.0
CH2_k127_4259647_2 tellurium resistance protein K01802,K05792 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 296.0
CH2_k127_4259647_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000005898 220.0
CH2_k127_4259647_4 Protein tyrosine kinase - - - 0.000000000001268 79.0
CH2_k127_4267896_0 Glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 1.749e-240 750.0
CH2_k127_4267896_1 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000006489 192.0
CH2_k127_4281090_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.225e-278 862.0
CH2_k127_4281090_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.171e-260 807.0
CH2_k127_4281090_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 420.0
CH2_k127_4281090_3 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 416.0
CH2_k127_4281090_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 366.0
CH2_k127_4281090_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000006403 206.0
CH2_k127_4281090_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000003387 190.0
CH2_k127_4281090_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000003425 161.0
CH2_k127_4281090_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000000003352 150.0
CH2_k127_4292426_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.627e-208 653.0
CH2_k127_4292426_1 PFAM Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 310.0
CH2_k127_4292426_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006401 276.0
CH2_k127_432609_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.995e-212 668.0
CH2_k127_432609_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 340.0
CH2_k127_432609_2 Nuclease-related domain - - - 0.000000000000000000000000000023 135.0
CH2_k127_4360366_0 of the major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 409.0
CH2_k127_4360366_1 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000105 168.0
CH2_k127_4427726_0 protein transport across the cell outer membrane K02452 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000003236 169.0
CH2_k127_4456024_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.89e-205 658.0
CH2_k127_4456024_1 DNA methylase - - - 0.0000000000000000000000000000000000000000000000001028 178.0
CH2_k127_4456024_2 Sulfatase K03760 - 2.7.8.43 0.000000000000003592 78.0
CH2_k127_4457402_0 tRNA synthetases class I (K) K04566 - 6.1.1.6 2.902e-240 754.0
CH2_k127_4457402_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 387.0
CH2_k127_4506384_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 1.263e-226 710.0
CH2_k127_4506384_1 Adenine specific DNA methylase Mod K00571,K07316,K07319 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 283.0
CH2_k127_45383_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.461e-293 920.0
CH2_k127_45383_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 416.0
CH2_k127_45383_2 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000003851 143.0
CH2_k127_4552722_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.032e-266 841.0
CH2_k127_4574743_0 Leucine-rich repeat (LRR) protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 482.0
CH2_k127_4615408_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000811 166.0
CH2_k127_4615408_1 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000003503 149.0
CH2_k127_4637320_0 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 4.64e-232 741.0
CH2_k127_4637320_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000004617 229.0
CH2_k127_4637320_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000006268 110.0
CH2_k127_4639958_0 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005438 273.0
CH2_k127_4639958_1 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.000000000000000000000000000000000000000000000001076 183.0
CH2_k127_4650179_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 361.0
CH2_k127_4650179_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 353.0
CH2_k127_4670100_0 N-6 DNA methylase K03427 - 2.1.1.72 2.577e-238 743.0
CH2_k127_4670100_1 PFAM restriction modification system DNA specificity K01154 - 3.1.21.3 0.000000002913 62.0
CH2_k127_4671792_0 N-6 DNA Methylase - - - 1.844e-248 776.0
CH2_k127_4671792_1 S1 P1 nuclease - - - 0.000000000000000000000000000000000000000000000000000004233 196.0
CH2_k127_4680883_0 type II secretion K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 476.0
CH2_k127_4680883_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000004741 180.0
CH2_k127_4680883_2 - - - - 0.0000000000000000000001354 103.0
CH2_k127_4691154_0 Transmembrane secretion effector - - - 1.052e-229 724.0
CH2_k127_4691154_1 - - - - 0.00000000000000000000000000000000000000000007278 165.0
CH2_k127_4692704_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 482.0
CH2_k127_4692704_1 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000005105 228.0
CH2_k127_4692704_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000002758 157.0
CH2_k127_4693959_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 531.0
CH2_k127_4693959_1 Aldo keto K00002,K06221 GO:0000166,GO:0003674,GO:0003824,GO:0004033,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0070402,GO:0097159,GO:1901265,GO:1901363 1.1.1.2,1.1.1.346 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 445.0
CH2_k127_4693959_2 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000784 425.0
CH2_k127_4693959_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 390.0
CH2_k127_4693959_4 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 338.0
CH2_k127_4693959_5 domain, Protein K03112 - - 0.0000000000000000000000000000000000000000000000000000000000000003154 226.0
CH2_k127_4693959_6 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000271 108.0
CH2_k127_4693959_8 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000000000000004335 82.0
CH2_k127_4699423_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1287.0
CH2_k127_4699423_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000002762 88.0
CH2_k127_4699990_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 615.0
CH2_k127_4699990_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000005376 160.0
CH2_k127_4718499_0 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 443.0
CH2_k127_4718499_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 395.0
CH2_k127_4718499_2 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 319.0
CH2_k127_4718499_3 - - - - 0.0000000000000000000004269 101.0
CH2_k127_472144_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 381.0
CH2_k127_472144_1 PFAM Lipase, class 3 K01046 - 3.1.1.3 0.00000000000000000000000000000009581 139.0
CH2_k127_4723347_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 604.0
CH2_k127_4723347_1 Belongs to the binding-protein-dependent transport system permease family K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 601.0
CH2_k127_4723347_2 PFAM chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001429 296.0
CH2_k127_4723347_3 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000133 243.0
CH2_k127_4725002_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1379.0
CH2_k127_4725002_1 Galactose-3-O-sulfotransferase - - - 0.0000288 53.0
CH2_k127_47261_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 306.0
CH2_k127_47261_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000002965 250.0
CH2_k127_47261_2 Domain of unknown function (DUF4845) - - - 0.0000000000001982 75.0
CH2_k127_4729717_0 PFAM Type II secretion system protein E K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001216 244.0
CH2_k127_4729717_1 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000116 208.0
CH2_k127_4729717_2 PFAM cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000001795 210.0
CH2_k127_4729717_3 CHASE - - - 0.0000000000000000000000000000000000000000000000000002235 191.0
CH2_k127_4729717_4 COG0526 Thiol-disulfide isomerase and thioredoxins K03673 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000005918 183.0
CH2_k127_4729717_5 response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000009313 177.0
CH2_k127_4729717_6 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000008194 169.0
CH2_k127_4729717_7 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000004748 121.0
CH2_k127_4729717_9 COG2863 Cytochrome c553 - - - 0.00000000000000000000002277 104.0
CH2_k127_4736259_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 433.0
CH2_k127_4736259_1 pilus modification protein PilV K02671 - - 0.000000000000000000000001123 110.0
CH2_k127_4736259_2 pilus assembly protein PilW K02672 - - 0.00000000000000001968 84.0
CH2_k127_4736259_3 Type II transport protein GspH K08084 - - 0.0000000008038 67.0
CH2_k127_4761320_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.513e-238 743.0
CH2_k127_4761320_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000004346 242.0
CH2_k127_4761320_2 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000007716 231.0
CH2_k127_4771547_0 Large extracellular alpha-helical protein K06894 - - 8.735e-251 795.0
CH2_k127_4835760_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 2.102e-194 614.0
CH2_k127_484889_0 Shoulder domain K17266 - - 0.0 1180.0
CH2_k127_4869132_0 MMPL family K07003 - - 2.066e-245 779.0
CH2_k127_4869132_1 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 523.0
CH2_k127_4874783_0 Histidine kinase K07716 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 419.0
CH2_k127_4874783_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 316.0
CH2_k127_4874783_2 biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000000001009 163.0
CH2_k127_4885768_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 583.0
CH2_k127_4885768_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 589.0
CH2_k127_4885768_2 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 406.0
CH2_k127_4885768_3 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 350.0
CH2_k127_4885768_4 Peptidase C26 K01658,K01664 GO:0000162,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006575,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009108,GO:0009308,GO:0009309,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042398,GO:0042401,GO:0042430,GO:0042435,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046820,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 305.0
CH2_k127_4885768_6 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000005772 51.0
CH2_k127_4885768_7 pre-mRNA processing factor 4 (PRP4) like K12662 GO:0000375,GO:0000377,GO:0000398,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016074,GO:0017069,GO:0017070,GO:0030532,GO:0030621,GO:0032991,GO:0034247,GO:0034470,GO:0034641,GO:0034660,GO:0043144,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045292,GO:0046483,GO:0046540,GO:0071704,GO:0090304,GO:0097159,GO:0097525,GO:0097526,GO:0120114,GO:1901360,GO:1901363,GO:1990904 - 0.00002833 54.0
CH2_k127_4887092_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1463.0
CH2_k127_4887092_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 2.211e-237 742.0
CH2_k127_4888912_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000006705 57.0
CH2_k127_4893862_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 7.442e-195 616.0
CH2_k127_4893862_1 peptidase, S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 286.0
CH2_k127_4893862_2 B-1 B cell differentiation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001395 282.0
CH2_k127_490347_0 Inorganic H+ pyrophosphatase K15987 - 3.6.1.1 6.123e-240 754.0
CH2_k127_490347_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.938e-208 655.0
CH2_k127_490347_2 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 297.0
CH2_k127_490347_3 Papain family cysteine protease - - - 0.000000000003905 72.0
CH2_k127_4984316_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 316.0
CH2_k127_4984316_1 protein histidine kinase activity - - - 0.0000000000001675 72.0
CH2_k127_4994147_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 614.0
CH2_k127_4994147_1 similarity to GB CAD86359.1 - - - 0.0000000000000000000001918 98.0
CH2_k127_500513_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 458.0
CH2_k127_500513_1 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 340.0
CH2_k127_5017268_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 5.329e-301 935.0
CH2_k127_5017268_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 452.0
CH2_k127_5017268_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000001047 105.0
CH2_k127_5020127_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 402.0
CH2_k127_5020127_1 component I K01665 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 367.0
CH2_k127_5020127_2 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000002652 173.0
CH2_k127_5091460_0 phosphate transporter K03306,K16322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 449.0
CH2_k127_5091460_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004375 253.0
CH2_k127_5091460_2 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.00000000000000000000000000000000000000000004074 169.0
CH2_k127_5091460_3 subunit of a heme lyase K02200 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - 0.000000000000000000000000000000000000001081 152.0
CH2_k127_5095574_0 PAS PAC sensor hybrid histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 518.0
CH2_k127_5106908_0 oxidoreductase FAD NAD(P)-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 417.0
CH2_k127_5106908_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 369.0
CH2_k127_5106908_2 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000005316 193.0
CH2_k127_5106908_3 toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000000000000485 188.0
CH2_k127_5106908_4 NTP binding protein (Contains STAS domain) K07122 - - 0.00000000000000001955 86.0
CH2_k127_5124925_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 424.0
CH2_k127_5124925_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000009285 64.0
CH2_k127_5166186_0 Hypothetical glycosyl hydrolase family 13 K11931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 624.0
CH2_k127_5166186_1 PFAM Glycosyl transferase family 2 K00752,K11936 - 2.4.1.212 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 552.0
CH2_k127_5166186_2 Poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA K11935 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 328.0
CH2_k127_5166186_3 Tellurite resistance K05793 - - 0.000000000000000000000000000000000000000000000000001243 186.0
CH2_k127_5166186_4 RNA-binding protein - - - 0.000000000000000000000000006322 113.0
CH2_k127_5166186_5 Sodium calcium exchanger K07301 - - 0.0000000000000000241 83.0
CH2_k127_5203136_0 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000008566 149.0
CH2_k127_5211122_0 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 351.0
CH2_k127_5211122_1 Trypsin-like serine protease K01312 - 3.4.21.4 0.00000000000000000000000000000000000000000000000000000005046 209.0
CH2_k127_5211122_2 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000005882 183.0
CH2_k127_5211122_3 Domain of unknown function DUF29 - - - 0.000000000000000000002475 95.0
CH2_k127_5222927_0 Histidine kinase A domain protein K07678 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 437.0
CH2_k127_5239629_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 414.0
CH2_k127_5239629_1 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 301.0
CH2_k127_5239629_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000004396 145.0
CH2_k127_5240884_0 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000349 252.0
CH2_k127_5240884_1 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000292 217.0
CH2_k127_5240884_2 helicase - - - 0.000000000000000000000000000000007099 132.0
CH2_k127_5245954_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 559.0
CH2_k127_5245954_1 TIGRFAM FimV C-terminal domain K08086 - - 0.00000000000000000000000000000000000000000000000007573 188.0
CH2_k127_5288906_0 PFAM Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 341.0
CH2_k127_5288906_1 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000000004545 216.0
CH2_k127_5288906_2 Putative metallopeptidase - - - 0.000000000000000004479 92.0
CH2_k127_5305931_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 542.0
CH2_k127_5305931_1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.000000008543 56.0
CH2_k127_5305931_2 - - - - 0.0000003583 51.0
CH2_k127_5336151_0 PFAM Bacterial type II secretion system protein F domain K02653 - - 0.0000000000000000000000000000000000000000000000000002229 198.0
CH2_k127_5336151_1 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.0000000000000000000002983 102.0
CH2_k127_5336151_2 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000476 63.0
CH2_k127_5341031_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 438.0
CH2_k127_5341031_1 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000002338 229.0
CH2_k127_5341031_2 - - - - 0.000000000000000000000000000000000000000000000000000001022 194.0
CH2_k127_5341031_3 N-6 DNA Methylase - - - 0.00000000000000000000000000001554 119.0
CH2_k127_5341031_4 NusG domain II - - - 0.000000000000000001436 92.0
CH2_k127_5350151_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 GO:0003674,GO:0003824,GO:0004076,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002863 259.0
CH2_k127_5350151_1 - - - - 0.00000000000000000000000000000000000000000000000004974 182.0
CH2_k127_5350151_2 protein conserved in cyanobacteria - - - 0.00000000000000000000000000000000007638 136.0
CH2_k127_5356646_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006633 235.0
CH2_k127_5356646_1 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000009056 229.0
CH2_k127_5356646_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000006336 223.0
CH2_k127_5356646_3 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000005701 156.0
CH2_k127_5361059_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.94e-209 659.0
CH2_k127_5361059_1 chlorophyll binding K03286,K03640 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 - 0.00000000000000000000000001581 111.0
CH2_k127_5365698_0 type II restriction enzyme, methylase - - - 2.239e-288 900.0
CH2_k127_5365698_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 432.0
CH2_k127_5386972_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 512.0
CH2_k127_5386972_1 MotA TolQ ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 297.0
CH2_k127_5386972_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000002943 201.0
CH2_k127_5386972_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0043906,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 0.00000000000000003471 82.0
CH2_k127_5395631_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 413.0
CH2_k127_5395631_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 422.0
CH2_k127_5395631_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000339 275.0
CH2_k127_5395631_3 - - - - 0.0000000000000000000000000000000006351 135.0
CH2_k127_5395631_4 - - - - 0.000000000000000000000000000003221 124.0
CH2_k127_5395631_5 - - - - 0.0000000000000000000000000006171 117.0
CH2_k127_539806_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1936.0
CH2_k127_539806_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1904.0
CH2_k127_539806_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000001002 54.0
CH2_k127_539806_2 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 360.0
CH2_k127_539806_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 336.0
CH2_k127_539806_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 330.0
CH2_k127_539806_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 294.0
CH2_k127_539806_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000291 244.0
CH2_k127_539806_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002811 198.0
CH2_k127_539806_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000003405 154.0
CH2_k127_539806_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000009957 124.0
CH2_k127_5407172_0 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 560.0
CH2_k127_5407172_1 Uncharacterised protein family (UPF0014) K02069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 314.0
CH2_k127_5407172_2 Glycosyltransferase like family K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 311.0
CH2_k127_5407172_3 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000003014 232.0
CH2_k127_5407172_4 PFAM ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000003926 201.0
CH2_k127_5407172_5 site-specific DNA-methyltransferase (adenine-specific) activity K03427 - 2.1.1.72 0.00000000000000000000000000009977 133.0
CH2_k127_542149_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 373.0
CH2_k127_542149_1 ATP diphosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000002437 233.0
CH2_k127_5432506_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 3.988e-266 828.0
CH2_k127_5432506_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.299e-228 716.0
CH2_k127_5432506_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006167 413.0
CH2_k127_5432506_3 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002164 246.0
CH2_k127_5432506_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000002626 142.0
CH2_k127_5456309_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 6.116e-215 673.0
CH2_k127_5456309_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001856 235.0
CH2_k127_5456309_2 Domain of unknown function DUF29 - - - 0.0000000000000000000000000000000000000000004696 161.0
CH2_k127_5456309_3 protein conserved in cyanobacteria - - - 0.0000000000000000000002557 102.0
CH2_k127_5461101_0 Protein of unknown function (DUF1152) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 326.0
CH2_k127_5465611_0 COG0348 Polyferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 460.0
CH2_k127_5465611_1 Leucine-rich repeat - - - 0.0000000000000000000000008071 110.0
CH2_k127_5465611_2 toxin-antitoxin pair type II binding K08591,K19159 - 2.3.1.15 0.0000000000008535 73.0
CH2_k127_5465611_3 DNA methylase N-4 N-6 domain K00571 - 2.1.1.72 0.000000007035 57.0
CH2_k127_5482801_0 glycosyl transferase, family 2 K20444 - - 3.236e-219 691.0
CH2_k127_5482801_1 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005435 263.0
CH2_k127_548596_0 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 434.0
CH2_k127_548596_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000173 200.0
CH2_k127_548596_2 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000005329 198.0
CH2_k127_548596_3 of membrane protease K07340 - - 0.000000000000000000000000000000000000000005234 159.0
CH2_k127_5550135_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 GO:0000166,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 459.0
CH2_k127_5550135_1 TIGRFAM general secretion pathway protein F K02455 - - 0.00001929 46.0
CH2_k127_55780_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 350.0
CH2_k127_55780_1 Belongs to the peptidase S8 family K01342,K12287,K20276 - 3.4.21.62 0.00000000000000000000000000000000000000000004178 167.0
CH2_k127_55780_2 ATP synthase subunit C K02124 - - 0.0000000000000000000000000000000000000000000662 164.0
CH2_k127_55780_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000006988 93.0
CH2_k127_55780_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000001524 84.0
CH2_k127_55780_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042221,GO:0042364,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.000000001681 59.0
CH2_k127_55780_6 domain, Protein - - - 0.0006604 49.0
CH2_k127_5647894_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.661e-258 803.0
CH2_k127_5647894_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.00000000000000000766 84.0
CH2_k127_567098_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1073.0
CH2_k127_567098_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 484.0
CH2_k127_567098_2 Protein of unknown function (DUF721) - - - 0.0000001172 59.0
CH2_k127_5677079_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1044.0
CH2_k127_5677079_1 chlorophyll binding K03286,K03640 GO:0000746,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009597,GO:0009605,GO:0009607,GO:0009615,GO:0009987,GO:0015267,GO:0015288,GO:0016020,GO:0016021,GO:0016032,GO:0019058,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030260,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032991,GO:0033554,GO:0034220,GO:0042802,GO:0043207,GO:0044403,GO:0044409,GO:0044419,GO:0044425,GO:0044462,GO:0044464,GO:0044764,GO:0046718,GO:0046930,GO:0050896,GO:0051179,GO:0051234,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051806,GO:0051828,GO:0055085,GO:0071944,GO:0098796 - 0.00000000000000000000000001581 111.0
CH2_k127_5813465_0 guanyl-nucleotide exchange factor activity K12287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 521.0
CH2_k127_5832099_0 Penicillin-Binding Protein C-terminus Family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008091 439.0
CH2_k127_5832099_1 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 381.0
CH2_k127_5832099_2 DEAD-like helicases superfamily K01156 - 3.1.21.5 0.00000000000000000000000000000000000000000000000000000000000000000000004762 254.0
CH2_k127_5832099_3 DDE superfamily endonuclease - - - 0.000000000146 62.0
CH2_k127_5832099_4 Domain of Unknown Function (DUF928) - - - 0.000000003071 65.0
CH2_k127_5834373_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 506.0
CH2_k127_5834373_2 lipolytic protein G-D-S-L family - - - 0.0002138 50.0
CH2_k127_5843245_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 358.0
CH2_k127_5843245_1 LICD family - - - 0.0002769 49.0
CH2_k127_5917821_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 449.0
CH2_k127_5926719_0 PFAM Rhodanese-like K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000644 160.0
CH2_k127_5926719_1 PFAM peptidase M48 Ste24p K03799 - - 0.000000000000000000000000000000000000001188 157.0
CH2_k127_5926719_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000001485 65.0
CH2_k127_5943627_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.564e-286 889.0
CH2_k127_5948139_0 phosphorelay sensor kinase activity K03406,K07216,K07315,K20971 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 403.0
CH2_k127_5948139_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000002123 197.0
CH2_k127_5951579_0 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 312.0
CH2_k127_5951579_1 UPF0114 protein - - - 0.0000000000000000000000000000000000000000000000000000005209 199.0
CH2_k127_5951579_3 Virulence protein RhuM family - - - 0.00003745 46.0
CH2_k127_5966809_0 Type III restriction enzyme, res subunit K01156 - 3.1.21.5 0.0 1024.0
CH2_k127_5966809_1 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 509.0
CH2_k127_5966809_2 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 500.0
CH2_k127_5966809_3 Domain of unknown function (DUF4276) - - - 0.00000000000000000000000000000000000000000001021 169.0
CH2_k127_6012940_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 479.0
CH2_k127_6012940_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000003556 222.0
CH2_k127_6020209_0 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 454.0
CH2_k127_6020209_1 - - - - 0.0000000000000000000000000000004061 129.0
CH2_k127_6020209_2 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000001835 74.0
CH2_k127_6020209_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000007375 66.0
CH2_k127_6020209_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0001857 44.0
CH2_k127_6086525_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 442.0
CH2_k127_6086525_1 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000000000000000000000004419 219.0
CH2_k127_6135709_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 359.0
CH2_k127_6165937_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 551.0
CH2_k127_6165937_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 367.0
CH2_k127_6165937_2 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 350.0
CH2_k127_6165937_3 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000006229 175.0
CH2_k127_6193896_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000816 181.0
CH2_k127_6193896_1 - - - - 0.0000000000000000000003217 107.0
CH2_k127_6193896_2 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 0.00000000005147 65.0
CH2_k127_6194788_0 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000001531 248.0
CH2_k127_6194788_1 von willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000009104 222.0
CH2_k127_6194788_2 - - - - 0.0000000000000000000000000000000000000000000007801 175.0
CH2_k127_6194788_3 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000005583 158.0
CH2_k127_6194788_4 nuclease activity K18828 - - 0.0000000001412 63.0
CH2_k127_622540_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 421.0
CH2_k127_622540_1 cyclic nucleotide binding K01999,K07001 - - 0.00000000000000000000000000000000000000000000000000000000000331 212.0
CH2_k127_622540_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000008832 166.0
CH2_k127_622540_3 - - - - 0.0000000000000000000000002311 110.0
CH2_k127_622540_4 DDE superfamily endonuclease - - - 0.000000000000003401 75.0
CH2_k127_6236109_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 554.0
CH2_k127_6236109_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000006386 166.0
CH2_k127_6240895_0 recA bacterial DNA recombination protein K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 1.185e-195 632.0
CH2_k127_6240895_1 PFAM aminotransferase class-III K00819,K00821 - 2.6.1.11,2.6.1.13,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 560.0
CH2_k127_6240895_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 441.0
CH2_k127_6240895_3 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000002828 238.0
CH2_k127_6240895_4 TIGRFAM CRISPR-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000001077 214.0
CH2_k127_6240895_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000002895 208.0
CH2_k127_6240895_6 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000004675 139.0
CH2_k127_6240895_7 - - - - 0.0000000000000000003705 88.0
CH2_k127_6246038_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.721e-216 675.0
CH2_k127_6246038_1 Type II and III secretion system protein - - - 7.568e-213 682.0
CH2_k127_6246038_2 general secretion pathway protein K02455 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004702 539.0
CH2_k127_6308621_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 460.0
CH2_k127_6308621_1 Beta propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 408.0
CH2_k127_6308621_2 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 313.0
CH2_k127_6308621_3 PFAM Phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.000000000000000000000000000000000000000009118 156.0
CH2_k127_6308621_4 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000000005713 147.0
CH2_k127_6346781_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 2.501e-216 676.0
CH2_k127_6346781_1 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000002456 192.0
CH2_k127_6346781_2 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000004355 124.0
CH2_k127_636288_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004225 260.0
CH2_k127_636288_1 ADP binding - - - 0.00000000000000000000000009188 118.0
CH2_k127_6363248_0 PFAM Aminotransferase class I and II K14261 - - 1.732e-216 676.0
CH2_k127_6363248_1 Belongs to the N(4) N(6)-methyltransferase family K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 419.0
CH2_k127_6363248_2 ABC transporter (permease) K02033,K13894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 311.0
CH2_k127_6363248_3 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 295.0
CH2_k127_6363248_4 ATPase component K02074,K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 287.0
CH2_k127_6363248_5 Tellurite resistance K05793 - - 0.0000000000000000001055 92.0
CH2_k127_64035_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1042.0
CH2_k127_64035_1 FAD dependent oxidoreductase K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.286e-209 656.0
CH2_k127_64035_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 322.0
CH2_k127_6481647_0 PFAM tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005385 528.0
CH2_k127_6481647_1 Membrane protease subunits, stomatin prohibitin homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 451.0
CH2_k127_6481647_2 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001187 251.0
CH2_k127_6481647_3 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 GO:0003674,GO:0003824,GO:0004112,GO:0004114,GO:0004115,GO:0005488,GO:0005506,GO:0008081,GO:0008150,GO:0008198,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0042545,GO:0042578,GO:0043167,GO:0043169,GO:0045229,GO:0046872,GO:0046914,GO:0071554,GO:0071555,GO:0071840 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000001125 249.0
CH2_k127_6481647_4 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000003523 57.0
CH2_k127_6518182_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 570.0
CH2_k127_6518182_1 Permease YjgP YjgQ K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 366.0
CH2_k127_6518182_2 Permease YjgP YjgQ K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 348.0
CH2_k127_6518182_3 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 335.0
CH2_k127_6518182_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001145 262.0
CH2_k127_6518182_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000002761 117.0
CH2_k127_6553257_0 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 GO:0000302,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009061,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015980,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042221,GO:0042493,GO:0043565,GO:0044212,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0045893,GO:0045935,GO:0048037,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0060255,GO:0065007,GO:0071731,GO:0080090,GO:0097159,GO:0097366,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000007617 198.0
CH2_k127_6553257_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000005871 87.0
CH2_k127_6556629_0 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001517 265.0
CH2_k127_6556629_1 O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000001763 253.0
CH2_k127_6556629_2 Glycosyl transferase, family 2 - - - 0.000000002311 61.0
CH2_k127_6583450_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1e-216 681.0
CH2_k127_6583450_1 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 308.0
CH2_k127_6583450_2 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001891 280.0
CH2_k127_6583450_3 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000004936 143.0
CH2_k127_6601760_0 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 350.0
CH2_k127_6601760_1 guanyl-nucleotide exchange factor activity K12287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 313.0
CH2_k127_6601760_2 geranylgeranyl reductase activity K10960,K17830 - 1.3.1.101,1.3.1.111,1.3.1.83,1.3.7.11 0.0000000000000000000000000000000000000000000004306 178.0
CH2_k127_6603404_0 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 488.0
CH2_k127_6603404_1 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 368.0
CH2_k127_6603404_2 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 379.0
CH2_k127_6603404_3 Protein of unknown function (DUF3782) - - - 0.0000000000000000000000000000000000000000000000000000000000000006958 225.0
CH2_k127_6603404_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000001225 210.0
CH2_k127_6603404_5 - - - - 0.00000000000000000001928 98.0
CH2_k127_6623011_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 5.374e-259 803.0
CH2_k127_6623011_1 Ami_2 - - - 0.00000000001318 67.0
CH2_k127_6644143_0 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002024 276.0
CH2_k127_6644143_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000001993 145.0
CH2_k127_6644143_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000008191 94.0
CH2_k127_6644143_3 DDE superfamily endonuclease - - - 0.00000001873 58.0
CH2_k127_6644143_4 DDE superfamily endonuclease - - - 0.00000002891 54.0
CH2_k127_6645835_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000004359 265.0
CH2_k127_6645835_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001543 229.0
CH2_k127_6645835_2 Domain of unknown function (DUF4160) - - - 0.00000000000000000000000000000000000000007741 152.0
CH2_k127_6645835_3 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000000000000009033 137.0
CH2_k127_6645835_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000001199 133.0
CH2_k127_6645835_5 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.00000000000000000000000003999 114.0
CH2_k127_6666308_0 magnesium chelatase K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 321.0
CH2_k127_6666308_1 Membrane fusogenic activity K09806 - - 0.0000000000000002369 81.0
CH2_k127_6668985_0 TIGRFAM TIGR02099 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 480.0
CH2_k127_6668985_1 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001403 97.0
CH2_k127_6686997_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 5.579e-284 886.0
CH2_k127_6686997_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 369.0
CH2_k127_6698215_0 Domain of unknown function (DUF3400) - - - 7.536e-288 898.0
CH2_k127_6750477_0 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 512.0
CH2_k127_6750477_1 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000000000000000000002751 235.0
CH2_k127_6750477_2 phosphate transporter K03306 - - 0.00006371 46.0
CH2_k127_6776671_0 CHAT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000729 450.0
CH2_k127_6776671_1 WD-40 repeat - - - 0.00000000000000001293 89.0
CH2_k127_6787168_0 protein conserved in bacteria (DUF2333) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 407.0
CH2_k127_6787168_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 335.0
CH2_k127_6787168_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000002349 228.0
CH2_k127_6787168_3 Smr protein - - - 0.0000000000000000000000000000000003015 138.0
CH2_k127_6789341_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 8.563e-228 709.0
CH2_k127_6789341_1 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 525.0
CH2_k127_6789341_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000001032 243.0
CH2_k127_6789341_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000193 119.0
CH2_k127_6834752_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 421.0
CH2_k127_6834752_1 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.000000000000000000000000000000000000000000000000002529 184.0
CH2_k127_6847374_0 Membrane K08974 - - 0.0000000000000000000000000000000000000000000000000000000000000000002406 241.0
CH2_k127_6847374_1 - - - - 0.0000000000000000000000000000000005403 136.0
CH2_k127_6847374_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.00000000000001558 74.0
CH2_k127_6858417_0 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 368.0
CH2_k127_6858417_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000746 252.0
CH2_k127_6858417_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000001001 224.0
CH2_k127_6895048_0 CHAT domain - - - 5.744e-236 753.0
CH2_k127_6895048_1 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 433.0
CH2_k127_6895048_2 TIGRFAM filamentous hemagglutinin family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000001951 196.0
CH2_k127_6895048_3 TonB C terminal K03832 - - 0.00000000005144 68.0
CH2_k127_6904944_0 Peptidase M50 K16922 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008869 279.0
CH2_k127_6904944_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000007924 51.0
CH2_k127_6956108_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.56e-307 967.0
CH2_k127_6956108_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000171 154.0
CH2_k127_6956108_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000005784 119.0
CH2_k127_696552_0 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 439.0
CH2_k127_6996112_0 Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55) K13007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 386.0
CH2_k127_6996112_1 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 381.0
CH2_k127_6996112_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 346.0
CH2_k127_6996112_3 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015232,GO:0015886,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019897,GO:0019898,GO:0022857,GO:0031224,GO:0031234,GO:0032991,GO:0042623,GO:0043190,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:1901678,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009077 274.0
CH2_k127_6996112_4 Glycolate oxidase K11473 - - 0.00003111 55.0
CH2_k127_6997817_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07711,K19694 - 2.7.13.3 0.0 1266.0
CH2_k127_6997817_1 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 2.851e-212 674.0
CH2_k127_6997817_2 CHAT domain - - - 1.834e-204 661.0
CH2_k127_6997817_3 Domain of Unknown Function (DUF349) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 628.0
CH2_k127_6997817_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 359.0
CH2_k127_6997817_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001133 270.0
CH2_k127_6997817_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007201 236.0
CH2_k127_6997817_7 Mitochondrial PGP phosphatase K07015 - - 0.00000000000000000000000000000000000000000000000000000000002504 212.0
CH2_k127_6997817_8 CHAT domain - - - 0.000000000000000000000000000000000000000000000001449 178.0
CH2_k127_6997817_9 signal-transduction protein containing cAMP-binding and CBS domains K06041 - 5.3.1.13 0.000000000000000000000000000000000000000007694 157.0
CH2_k127_7024988_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 471.0
CH2_k127_7024988_1 Belongs to the N(4) N(6)-methyltransferase family K00571,K07316 - 2.1.1.72 0.0000000000000001861 84.0
CH2_k127_7026133_0 PFAM pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 469.0
CH2_k127_7026133_1 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000004014 264.0
CH2_k127_7026133_2 Resolvase - - - 0.00004389 46.0
CH2_k127_7034490_0 cell division protein K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 336.0
CH2_k127_7034997_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 453.0
CH2_k127_7034997_1 queuosine biosynthesis protein QueD K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000005614 205.0
CH2_k127_7034997_2 PFAM Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000001563 192.0
CH2_k127_7034997_3 FxsA cytoplasmic membrane protein K07113 - - 0.00000000000101 74.0
CH2_k127_7094198_0 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 339.0
CH2_k127_7094198_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000949 102.0
CH2_k127_7094198_2 protein conserved in cyanobacteria - - - 0.00000000000000000003784 95.0
CH2_k127_7107420_0 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006339 267.0
CH2_k127_7107420_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.000000000000000000000000002791 115.0
CH2_k127_7128985_0 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 337.0
CH2_k127_7128985_1 - - - - 0.00000000000000000000000000000000000000000000005974 175.0
CH2_k127_7128985_2 Domain of unknown function (DUF1987) - - - 0.000000000000000000000000000002231 124.0
CH2_k127_7129299_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1212.0
CH2_k127_7129299_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 467.0
CH2_k127_7129299_2 Alpha/beta hydrolase family - - - 0.0000000000000008701 85.0
CH2_k127_7205282_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.684e-231 722.0
CH2_k127_7205282_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 321.0
CH2_k127_7210719_0 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 286.0
CH2_k127_7210719_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004318 261.0
CH2_k127_7210719_2 Glycosyl transferase, family 2 K00786 - - 0.000000000000000000000000000000000002364 141.0
CH2_k127_7218771_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 521.0
CH2_k127_7218771_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000005667 242.0
CH2_k127_7218771_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000008679 188.0
CH2_k127_7218771_3 Belongs to the heme-copper respiratory oxidase family - - - 0.0000000000000000000000000000000000000000000000005643 186.0
CH2_k127_7219665_0 Caspase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000974 271.0
CH2_k127_7219665_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000004605 234.0
CH2_k127_7219665_2 PFAM porin, Gram-negative type - - - 0.0000000000000000003059 100.0
CH2_k127_7222281_0 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 353.0
CH2_k127_7222281_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 328.0
CH2_k127_7222281_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 311.0
CH2_k127_7222281_3 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000003222 118.0
CH2_k127_7222281_4 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000001113 100.0
CH2_k127_7222281_5 guanyl-nucleotide exchange factor activity - - - 0.00000000000000000004557 100.0
CH2_k127_7222281_6 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000000003304 97.0
CH2_k127_7225832_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 1.214e-202 638.0
CH2_k127_7225832_1 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000004519 131.0
CH2_k127_7255265_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1463.0
CH2_k127_7255265_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 507.0
CH2_k127_7255265_2 Sterol carrier protein - - - 0.00000000000000000000000000000000000000000000000000000000005027 206.0
CH2_k127_7255265_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000001943 91.0
CH2_k127_7268737_0 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 624.0
CH2_k127_7268737_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 559.0
CH2_k127_7268737_2 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 541.0
CH2_k127_7268737_3 - - - - 0.00000000000000000000000000000000000000000000001435 175.0
CH2_k127_7269536_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 0.0000000000000000000000000000000000000000000000000000000000000002796 225.0
CH2_k127_7269536_1 zinc ion binding - - - 0.0000000000000000000000000000000028 141.0
CH2_k127_7294373_0 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 449.0
CH2_k127_7294373_1 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.0000000000000000000000000001122 126.0
CH2_k127_7297045_0 Na Pi-cotransporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 299.0
CH2_k127_7297045_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003918 280.0
CH2_k127_7297045_2 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004582 282.0
CH2_k127_7300956_0 conserved protein (DUF2081) - - - 5.615e-218 696.0
CH2_k127_7300956_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 609.0
CH2_k127_7300956_2 Phosphoadenosine phosphosulfate reductase family K19170 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 481.0
CH2_k127_7300956_3 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
CH2_k127_7300956_4 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 298.0
CH2_k127_7300956_5 redox protein, regulator of disulfide bond formation K07397 - - 0.00000000000000000000000000000000000000000000000000001364 191.0
CH2_k127_7300956_6 DNA sulfur modification protein DndD K19171 - - 0.00000000000000000000000000000000000000000000008237 173.0
CH2_k127_7312152_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB - - - 4.487e-211 662.0
CH2_k127_7312152_1 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000001352 175.0
CH2_k127_7312152_2 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 0.00000000000000000000000000000000000000003343 157.0
CH2_k127_73186_0 SMART von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 456.0
CH2_k127_73186_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000004302 237.0
CH2_k127_73186_2 Transposase - - - 0.000000003417 59.0
CH2_k127_7357809_0 HWE histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 586.0
CH2_k127_7357809_1 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00001663 48.0
CH2_k127_736343_0 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007808 284.0
CH2_k127_736343_1 - - - - 0.00000000000000000000000000000000000000000000000000000000002956 218.0
CH2_k127_736343_2 - - - - 0.000000000002174 74.0
CH2_k127_7378952_0 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 413.0
CH2_k127_7378952_1 PFAM Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000009852 204.0
CH2_k127_7378952_2 SPTR Sensory transduction system regulatory protein (Diguanylate cyclase (GGDEF) domain) - - - 0.0000000000000000000000000000000000000000000000003631 201.0
CH2_k127_7440176_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 502.0
CH2_k127_7440176_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000344 239.0
CH2_k127_7443619_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 316.0
CH2_k127_7443619_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000002068 73.0
CH2_k127_7443619_2 Belongs to the 'phage' integrase family - - - 0.00003771 48.0
CH2_k127_7449846_0 RQC K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 604.0
CH2_k127_7449846_1 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000000000000001736 94.0
CH2_k127_7492080_0 Outer membrane receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 519.0
CH2_k127_7492080_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 466.0
CH2_k127_7492080_2 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 291.0
CH2_k127_7492080_3 Topoisomerase DNA binding C4 zinc finger - - - 0.00000000000000000000000000000000000000000001461 170.0
CH2_k127_7492080_4 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.00000000000000000000000000000000000001441 147.0
CH2_k127_7492080_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000463 149.0
CH2_k127_7503681_0 Histidine kinase - - - 0.00000000000000000000000000000000000746 153.0
CH2_k127_7503681_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000003422 108.0
CH2_k127_7508226_0 OmpW family K07275 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 283.0
CH2_k127_7508226_1 OmpW family K07275 - - 0.00000000000000000000000000000000000000000000000002191 186.0
CH2_k127_7508226_2 DDE_Tnp_1-associated - - - 0.00000000000000000000000008996 110.0
CH2_k127_7518089_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 313.0
CH2_k127_7518089_1 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000005334 230.0
CH2_k127_7518089_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000002963 202.0
CH2_k127_7518089_3 N-6 DNA Methylase - - - 0.00000000000000000000000001888 109.0
CH2_k127_7518089_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000001961 103.0
CH2_k127_7518089_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000004441 83.0
CH2_k127_7518089_6 Transposase - - - 0.0001754 45.0
CH2_k127_7521017_0 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 402.0
CH2_k127_7521017_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 336.0
CH2_k127_7521017_2 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.00000000000000000000000000000000000000000000000000000004232 198.0
CH2_k127_7521017_3 - - - - 0.00000000000000000000000000001864 121.0
CH2_k127_7522408_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 345.0
CH2_k127_7522408_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000011 59.0
CH2_k127_7547589_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 576.0
CH2_k127_7547589_1 AI-2E family transporter K03548 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 369.0
CH2_k127_7547589_2 COG0450 Peroxiredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 319.0
CH2_k127_7547589_3 AI-2E family transporter K03548 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001063 261.0
CH2_k127_7547589_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000007886 72.0
CH2_k127_7547589_5 Transposase - - - 0.000001775 51.0
CH2_k127_7572300_0 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 323.0
CH2_k127_7572300_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 327.0
CH2_k127_7572300_2 CorA-like Mg2+ transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005303 265.0
CH2_k127_7572300_3 PFAM regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000004148 220.0
CH2_k127_7572300_4 Beta-L-arabinofuranosidase, GH127 - - - 0.0000000000000002674 93.0
CH2_k127_7587499_0 PBS lyase HEAT-like repeat - - - 0.0000000005223 67.0
CH2_k127_7587499_1 Chase2 domain K01768 - 4.6.1.1 0.0000000006001 70.0
CH2_k127_7592801_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009898 522.0
CH2_k127_7592801_1 serine-type endopeptidase activity K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 367.0
CH2_k127_761015_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 349.0
CH2_k127_761015_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000001881 224.0
CH2_k127_761015_2 Putative restriction endonuclease - - - 0.00000000000000002417 88.0
CH2_k127_7610410_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 6.902e-233 726.0
CH2_k127_7610410_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 5.136e-206 646.0
CH2_k127_7610410_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009518 248.0
CH2_k127_7610410_11 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004363 241.0
CH2_k127_7610410_12 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000268 231.0
CH2_k127_7610410_13 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000009076 214.0
CH2_k127_7610410_14 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000002647 214.0
CH2_k127_7610410_15 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000002427 220.0
CH2_k127_7610410_16 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000002392 195.0
CH2_k127_7610410_17 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000002888 195.0
CH2_k127_7610410_18 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000005045 187.0
CH2_k127_7610410_19 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000001345 178.0
CH2_k127_7610410_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 573.0
CH2_k127_7610410_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009894,GO:0009987,GO:0010467,GO:0010468,GO:0010608,GO:0015935,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031329,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043487,GO:0043488,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061013,GO:0065003,GO:0065007,GO:0065008,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903311,GO:1990904 - 0.00000000000000000000000000000000000000000000000014 179.0
CH2_k127_7610410_21 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000003007 169.0
CH2_k127_7610410_22 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000002015 165.0
CH2_k127_7610410_23 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000006443 164.0
CH2_k127_7610410_24 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000002566 160.0
CH2_k127_7610410_25 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000006689 159.0
CH2_k127_7610410_26 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000008309 147.0
CH2_k127_7610410_27 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000001861 145.0
CH2_k127_7610410_28 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000004785 141.0
CH2_k127_7610410_29 General Secretion Pathway protein K02457 - - 0.000000000000000000000000000000000008915 141.0
CH2_k127_7610410_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 443.0
CH2_k127_7610410_30 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000001052 115.0
CH2_k127_7610410_32 Ribosomal protein L30 K02907 - - 0.000000000000000008043 84.0
CH2_k127_7610410_33 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000005328 73.0
CH2_k127_7610410_34 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000001198 65.0
CH2_k127_7610410_4 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 439.0
CH2_k127_7610410_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 345.0
CH2_k127_7610410_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 329.0
CH2_k127_7610410_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 282.0
CH2_k127_7610410_8 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 283.0
CH2_k127_7610410_9 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003102 254.0
CH2_k127_7612065_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 294.0
CH2_k127_7612065_1 COGs COG2026 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.00000000005829 66.0
CH2_k127_7612065_2 - - - - 0.00000002322 58.0
CH2_k127_7644451_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 5.121e-255 797.0
CH2_k127_7644451_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.0004317 43.0
CH2_k127_7663964_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 290.0
CH2_k127_7663964_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000005791 176.0
CH2_k127_7663964_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000004696 115.0
CH2_k127_7663964_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000001894 85.0
CH2_k127_767565_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1689.0
CH2_k127_767565_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000002362 226.0
CH2_k127_767565_2 Staphylococcal nuclease homologue - - - 0.000000000000000000000000000000000003058 142.0
CH2_k127_7692596_0 Dynamin family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 563.0
CH2_k127_7692596_1 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 377.0
CH2_k127_7692596_2 phosphatase, C-terminal domain of histone macro H2A1 like protein - - - 0.0000000000000000000000000000000000000000000000000000000000192 210.0
CH2_k127_7692596_3 TaqI-like C-terminal specificity domain - - - 0.0000000000000000000000000000000000000000000000000000000004836 207.0
CH2_k127_7706086_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 9.461e-216 692.0
CH2_k127_7706086_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 528.0
CH2_k127_7706086_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 351.0
CH2_k127_7706086_3 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000951 291.0
CH2_k127_7706086_4 riboflavin synthase, alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
CH2_k127_7706086_5 GGDEF domain K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000008343 244.0
CH2_k127_7706086_6 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000000000000006831 177.0
CH2_k127_7706086_7 protein kinase activity - - - 0.000000000000000000000000000000000000000003566 158.0
CH2_k127_7706086_8 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000007151 59.0
CH2_k127_7720245_0 diguanylate cyclase (GGDEF) domain K21025 - - 1.533e-256 809.0
CH2_k127_7720245_1 von willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007105 243.0
CH2_k127_7745008_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 561.0
CH2_k127_7745008_1 guanylate kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 297.0
CH2_k127_7745008_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000002654 89.0
CH2_k127_7765875_0 Histidine kinase - - - 2.411e-234 747.0
CH2_k127_7765875_1 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 572.0
CH2_k127_7765875_2 Domain of unknown function (DUF4154) - - - 0.000000000000000000000000000000009167 134.0
CH2_k127_7804583_0 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 447.0
CH2_k127_7804583_1 PFAM Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000003738 167.0
CH2_k127_7804583_2 Protein conserved in bacteria - - - 0.00000000000000000001916 104.0
CH2_k127_7805025_0 modulates the activities of several proteins which are inactive in their K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 371.0
CH2_k127_7805025_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 297.0
CH2_k127_7805025_2 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000002459 216.0
CH2_k127_785579_0 CHAT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 520.0
CH2_k127_785579_1 N-6 DNA Methylase K03427 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 298.0
CH2_k127_7898830_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K19696 - 2.4.2.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 300.0
CH2_k127_7898830_1 phosphoribosyltransferase K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000001019 214.0
CH2_k127_7898830_2 glycosyl transferase, family 2 K20444 - - 0.0000000000000000000000000115 117.0
CH2_k127_7898830_3 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000002689 98.0
CH2_k127_7915082_0 enzyme of heme biosynthesis K02496 - 2.1.1.107 0.000000000000000000000000000008597 132.0
CH2_k127_7915082_1 Glycosyl transferases group 1 - - - 0.000000000000000000008836 93.0
CH2_k127_7929090_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 572.0
CH2_k127_7929090_1 membrane transporter protein - - - 0.0000000000000000000000000000000000000001936 154.0
CH2_k127_7933813_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 563.0
CH2_k127_7933813_1 Pfam:Methyltransf_26 - - - 0.00000000000000000000000000000002038 127.0
CH2_k127_794223_0 Cytochrome c-type biogenesis protein CcmF C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 322.0
CH2_k127_7975837_0 Oxidoreductase K19813 - 1.1.5.9 0.00000000000000000000000000001137 123.0
CH2_k127_7975837_1 Type II transport protein GspH K02457 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000001273 68.0
CH2_k127_8024855_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 484.0
CH2_k127_8024855_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 425.0
CH2_k127_8024855_2 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 316.0
CH2_k127_8024855_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004166 265.0
CH2_k127_8024855_4 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000002965 250.0
CH2_k127_8024855_5 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.000000000000000000000000000000000000000000000005403 177.0
CH2_k127_8024855_6 Sigma 54 modulation protein K05808 - - 0.000000000000000000000000000000000000000172 152.0
CH2_k127_8024855_7 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.000000000000000000000000000000353 129.0
CH2_k127_8024855_8 transposase activity - - - 0.000000000000000000000000000001484 121.0
CH2_k127_8032934_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 400.0
CH2_k127_8032934_1 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 393.0
CH2_k127_8097510_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 2.304e-209 668.0
CH2_k127_8097510_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 529.0
CH2_k127_8097510_2 - - - - 0.0000000000000000000000000000000000000005319 152.0
CH2_k127_8097510_3 Hemerythrin HHE cation binding domain K07216 - - 0.000000000000000000000000000000000001066 143.0
CH2_k127_8097510_4 Nitroreductase family - - - 0.0000000000000000000000000000000000596 143.0
CH2_k127_8097510_5 Sulfatase - - - 0.00000000000000000000000000000254 130.0
CH2_k127_8122099_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 424.0
CH2_k127_8122099_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 383.0
CH2_k127_8122099_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 351.0
CH2_k127_8122099_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 300.0
CH2_k127_8122099_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000001024 202.0
CH2_k127_8122099_5 - - - - 0.000000000000000000000000002759 112.0
CH2_k127_8122099_6 Tetratricopeptide repeat - - - 0.00000000008214 76.0
CH2_k127_8191278_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 627.0
CH2_k127_8191278_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 444.0
CH2_k127_8191278_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000001336 172.0
CH2_k127_8191278_3 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00002848 49.0
CH2_k127_8202519_0 PFAM Archaeal ATPase - - - 0.0 1096.0
CH2_k127_8202519_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006985 425.0
CH2_k127_8202519_2 cytochrome c5 - - - 0.0000000000000000000000000000006366 130.0
CH2_k127_8230630_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.318e-218 685.0
CH2_k127_8232165_0 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000002318 239.0
CH2_k127_8232165_1 - - - - 0.0000000000000000000000000000000000000003361 162.0
CH2_k127_8232165_2 - - - - 0.000000000000001192 84.0
CH2_k127_8250737_0 Belongs to the mannose-6-phosphate isomerase type 2 family K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000001842 265.0
CH2_k127_8250737_1 Flavodoxin-like fold K03923 - - 0.000000000000000000000000000000000000000000000000000000000000009809 222.0
CH2_k127_8250737_2 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000005414 165.0
CH2_k127_8250737_3 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000003955 98.0
CH2_k127_8293826_0 transmembrane transport K02035,K15580 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006811,GO:0006820,GO:0006857,GO:0006869,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010876,GO:0015711,GO:0015718,GO:0015721,GO:0015833,GO:0015849,GO:0015850,GO:0030288,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042939,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:1900750 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 339.0
CH2_k127_8293826_1 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004012 278.0
CH2_k127_8305132_0 PFAM TonB-dependent receptor, plug K02014,K16089 - - 0.00000000000000000000000000000000000002494 164.0
CH2_k127_8321700_0 Eco57I restriction-modification methylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 477.0
CH2_k127_8335101_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 3.227e-238 742.0
CH2_k127_8357565_0 Four helix bundle sensory module for signal transduction K03406 - - 0.000000000000000000000000000000000000000000002731 186.0
CH2_k127_8357565_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.00000000000000000000001383 102.0
CH2_k127_8357565_2 C-terminal of Roc, COR, domain K13730 - - 0.0000008931 52.0
CH2_k127_8357565_4 Membrane - - - 0.0002627 51.0
CH2_k127_844148_0 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 390.0
CH2_k127_844148_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000002014 179.0
CH2_k127_8448246_0 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 533.0
CH2_k127_8448246_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 394.0
CH2_k127_8448246_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 289.0
CH2_k127_8448246_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000004765 212.0
CH2_k127_8448246_4 Transposase and inactivated derivatives - - - 0.0000000005452 62.0
CH2_k127_8456255_0 Glycosyl transferases group 1 K12995 - 2.4.1.348 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 426.0
CH2_k127_8456255_1 Transposase IS116 IS110 IS902 family protein K07486 - - 0.000000000000000002048 86.0
CH2_k127_8456255_2 Type I restriction-modification system methyltransferase subunit - - - 0.0001056 46.0
CH2_k127_8510369_0 Class III cytochrome C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 262.0
CH2_k127_8510369_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003399 233.0
CH2_k127_8510369_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000001569 56.0
CH2_k127_8513491_0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 351.0
CH2_k127_8513491_1 TIGRFAM flavoprotein, HI0933 family K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 345.0
CH2_k127_8575123_0 Part of a membrane complex involved in electron transport K03615 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 597.0
CH2_k127_8575123_1 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 372.0
CH2_k127_8575123_2 DNA Methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007146 293.0
CH2_k127_8575123_3 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000841 280.0
CH2_k127_8575123_4 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005164 248.0
CH2_k127_857908_0 transporter, dctM subunit - - - 2.663e-204 643.0
CH2_k127_857908_1 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000002615 207.0
CH2_k127_8607044_0 type I secretion outer membrane protein, TolC K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 441.0
CH2_k127_8607044_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 320.0
CH2_k127_8607044_2 L,D-transpeptidase catalytic domain - - - 0.0000000000003813 75.0
CH2_k127_8628729_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 3.131e-279 868.0
CH2_k127_8628729_1 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 3.479e-244 766.0
CH2_k127_8628729_10 - - - - 0.0000000004683 62.0
CH2_k127_8628729_2 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 298.0
CH2_k127_8628729_3 cytochrome c oxidase (Subunit II) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009017 243.0
CH2_k127_8628729_4 AsnC-type helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002967 231.0
CH2_k127_8628729_5 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000001782 218.0
CH2_k127_8628729_6 heme biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000002509 206.0
CH2_k127_8628729_7 Primase C terminal 1 (PriCT-1) - - - 0.00000000000000000000000000000000000000000124 168.0
CH2_k127_8628729_8 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000006028 117.0
CH2_k127_8628729_9 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.0000000000000000000000000001853 118.0
CH2_k127_8692321_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 361.0
CH2_k127_8692321_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 348.0
CH2_k127_8692321_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000066 250.0
CH2_k127_8692321_3 Divalent ion tolerance protein K03926 - - 0.000000000000000000000000000003703 122.0
CH2_k127_8692321_4 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.0000000000000000000001408 105.0
CH2_k127_871838_0 N-4 methylation of cytosine K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 534.0
CH2_k127_871838_1 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 457.0
CH2_k127_8772101_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000881 461.0
CH2_k127_8772101_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 434.0
CH2_k127_8772101_2 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001377 275.0
CH2_k127_8772101_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000000007615 124.0
CH2_k127_8772101_4 - - - - 0.00000000000000006248 82.0
CH2_k127_883672_0 Belongs to the GARS family K01945,K13713 - 6.3.2.6,6.3.4.13 5.604e-201 632.0
CH2_k127_883672_1 GGDEF domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 416.0
CH2_k127_883672_2 PFAM MoeZ MoeB domain K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 314.0
CH2_k127_883672_3 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000318 252.0
CH2_k127_883672_4 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000005477 134.0
CH2_k127_883672_5 Type I restriction-modification system methyltransferase subunit - - - 0.00000000000000000000002486 117.0
CH2_k127_883672_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000007851 95.0
CH2_k127_8838961_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 447.0
CH2_k127_8838961_1 PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.00000000000000000000000000000000000000000000000000000000001454 234.0
CH2_k127_8854839_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 491.0
CH2_k127_8854839_1 Sulfotransferase domain - - - 0.00000000000000000000000000000000006255 135.0
CH2_k127_8854839_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000006968 123.0
CH2_k127_8854839_3 Domain of unknown function (DUF4389) - - - 0.0000000000000008793 80.0
CH2_k127_8897602_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 437.0
CH2_k127_8897602_1 TIGRFAM 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 363.0
CH2_k127_8897602_2 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000288 273.0
CH2_k127_8897602_3 domain, Protein K03112 - - 0.0000000000000000000000008537 116.0
CH2_k127_9010667_0 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.0 1030.0
CH2_k127_9010667_1 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 370.0
CH2_k127_9010667_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000006771 221.0
CH2_k127_9010667_3 RDD family - - - 0.00000000000000000000000000000004325 130.0
CH2_k127_9010667_4 Protein of unknown function (DUF2491) - - - 0.000000000000000000000001389 112.0
CH2_k127_9032552_0 Paraquat-inducible protein A - - - 0.00000000000000000000000000000000004001 143.0
CH2_k127_9032552_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00008055 46.0
CH2_k127_9042830_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1023.0
CH2_k127_9042830_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.626e-289 898.0
CH2_k127_9042830_2 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000003478 194.0
CH2_k127_9042830_3 Regulatory protein, FmdB family - - - 0.0000000000000000000006636 96.0
CH2_k127_9196505_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000002222 192.0
CH2_k127_9196505_1 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000001297 94.0
CH2_k127_9213489_0 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 463.0
CH2_k127_9213489_1 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000003243 53.0
CH2_k127_9248584_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 395.0
CH2_k127_9257564_0 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 571.0
CH2_k127_9257564_1 nitrogen regulatory protein P-II K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000234 198.0
CH2_k127_9257564_2 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000001428 55.0
CH2_k127_9259801_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 573.0
CH2_k127_9259801_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 470.0
CH2_k127_9259801_2 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000001055 76.0
CH2_k127_9259801_3 Pentatricopeptide repeat-containing protein At1g22960 - GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000927 74.0
CH2_k127_926303_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005603 258.0
CH2_k127_926303_1 Tellurite resistance K05793 - - 0.000000000000000000000000000000000000000000004235 178.0
CH2_k127_926303_2 - - - - 0.00000000000000000000000000000002179 140.0
CH2_k127_926303_3 - - - - 0.0000003243 53.0
CH2_k127_9304892_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000003525 238.0
CH2_k127_9304892_1 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.0000000000000000000000000000000000000000001011 162.0
CH2_k127_9304892_2 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.0000000004449 60.0
CH2_k127_9304892_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000001509 57.0
CH2_k127_9329500_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000007236 187.0
CH2_k127_9354916_0 serine threonine protein kinase K11912 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 449.0
CH2_k127_9354916_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 377.0
CH2_k127_9373295_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 475.0
CH2_k127_9373295_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.297 0.000000000000000000000000000000000000575 143.0
CH2_k127_9373295_2 - K01992 - - 0.0000695 46.0
CH2_k127_9383812_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.048e-235 732.0
CH2_k127_9383812_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 306.0
CH2_k127_9383812_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005008 272.0
CH2_k127_9383812_3 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000001701 247.0
CH2_k127_9383812_4 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000006379 170.0
CH2_k127_9383812_5 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000009984 167.0
CH2_k127_9383812_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K01286,K07258 - 3.4.16.4 0.0000000002734 64.0
CH2_k127_9383812_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.00001506 47.0
CH2_k127_9397417_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 368.0
CH2_k127_9397417_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 337.0
CH2_k127_9397417_2 Pfam OmpA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 335.0
CH2_k127_9397417_3 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 301.0
CH2_k127_9398816_0 COG0643 Chemotaxis protein histidine kinase and related kinases K03407 GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009892,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010605,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032879,GO:0032991,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035556,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045937,GO:0046777,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0098561,GO:0140096,GO:1901564,GO:1901873,GO:1901875,GO:1902021,GO:2000145 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 524.0
CH2_k127_9398816_1 protein involved in response to NO K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 304.0
CH2_k127_9416014_0 site-specific DNA-methyltransferase (adenine-specific) activity K03427 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009701 398.0
CH2_k127_9416014_1 site-specific DNA-methyltransferase (adenine-specific) activity K03427 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000001137 229.0
CH2_k127_9420611_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000787 554.0
CH2_k127_9420611_1 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 365.0
CH2_k127_9420611_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000007014 193.0
CH2_k127_9441587_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 583.0
CH2_k127_9441587_1 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000003118 179.0
CH2_k127_9441587_2 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000001347 143.0
CH2_k127_9442176_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 377.0
CH2_k127_9442176_1 Nucleotidyltransferase substrate binding protein like - - - 0.00000000000000000000000000000000000002675 147.0
CH2_k127_9442176_2 chemotaxis signal transduction protein K06598 - - 0.0000000000000000000000000000000008689 136.0
CH2_k127_9442176_3 Nucleotidyltransferase domain - - - 0.00000000007074 66.0
CH2_k127_9447717_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.479e-239 758.0
CH2_k127_9447717_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 609.0
CH2_k127_9447717_2 of the major facilitator superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 293.0
CH2_k127_9447717_3 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000005464 183.0
CH2_k127_9447717_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000001506 105.0
CH2_k127_950415_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002693 250.0
CH2_k127_9509619_0 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008635 286.0
CH2_k127_9509619_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000004556 71.0
CH2_k127_9511844_0 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000001133 269.0
CH2_k127_9511844_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000004804 267.0
CH2_k127_9511844_2 PgaD-like protein K11937 - - 0.0000001665 58.0
CH2_k127_9515248_0 Histidine kinase A domain protein K07678 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 407.0
CH2_k127_9515557_0 Polysaccharide biosynthesis protein - - - 1.657e-202 640.0
CH2_k127_952820_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 394.0
CH2_k127_952820_1 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 295.0
CH2_k127_952820_2 General secretion pathway protein J K02459 - - 0.00000000000000000000000000000000000000000000000000000924 196.0
CH2_k127_952820_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000000003545 147.0
CH2_k127_952820_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K01286,K07258 - 3.4.16.4 0.00001525 53.0
CH2_k127_954060_0 - - - - 2.524e-234 756.0
CH2_k127_954060_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00002164 49.0
CH2_k127_9585381_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 8.786e-216 674.0
CH2_k127_9585381_1 Putative diguanylate phosphodiesterase K21023 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 487.0
CH2_k127_9585381_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 299.0
CH2_k127_9585381_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000001966 258.0
CH2_k127_9585381_4 - - - - 0.0000000000000000000000000000000000000000000004654 171.0
CH2_k127_9585381_5 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K00974 - 2.7.7.72 0.00000000000000000000000000000000008487 134.0
CH2_k127_9585381_6 Protein of unknown function (DUF3301) - - - 0.00000000000001113 78.0
CH2_k127_9585381_7 Domain of unknown function (DUF4154) - - - 0.000001243 58.0
CH2_k127_9586850_0 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001376 273.0
CH2_k127_9586850_1 Domain of unknown function (DUF4389) - - - 0.00001821 46.0
CH2_k127_9644503_0 Type II IV secretion system protein K02454,K02652 - - 8.596e-224 702.0
CH2_k127_9644503_1 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001167 257.0
CH2_k127_9644503_2 PFAM 17 kDa surface antigen - - - 0.00000000000000000000000000001488 126.0
CH2_k127_9644503_3 DDE superfamily endonuclease - - - 0.00000006804 55.0
CH2_k127_9644503_4 - - - - 0.0000003846 60.0
CH2_k127_9644503_5 PFAM Glycosyl transferase family 2 - - - 0.0002596 52.0
CH2_k127_9675270_0 Prokaryotic N-terminal methylation motif K02459 - - 0.000000000000000000000000000000000000000000000001841 181.0
CH2_k127_9675270_1 Prokaryotic N-terminal methylation motif K02458 - - 0.0000000000000000000000000000000000000000002856 162.0
CH2_k127_9675270_2 carbohydrate metabolic process - - - 0.0000000000000000000000000000000002183 143.0
CH2_k127_968724_0 metalloendopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 293.0
CH2_k127_968724_1 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005088 262.0
CH2_k127_968724_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000007288 95.0
CH2_k127_9688071_0 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 314.0
CH2_k127_9688071_1 helicase - - - 0.000000000000000000000000000000000000000000000000000000000000003218 224.0
CH2_k127_9688071_2 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000006255 135.0
CH2_k127_9688071_3 Helix-turn-helix domain - - - 0.00000000000000000004977 94.0
CH2_k127_9688071_4 chemotaxis protein K03408 - - 0.000000000000000003153 91.0
CH2_k127_9801734_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004918 269.0
CH2_k127_9801734_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000002892 191.0
CH2_k127_9801734_2 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.0000000000000000000000000000000000000000000000000000186 195.0
CH2_k127_9801734_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000007043 162.0
CH2_k127_9801734_4 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000182 87.0
CH2_k127_9850545_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 466.0
CH2_k127_98893_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007133 334.0
CH2_k127_98893_1 AI-2E family transporter K03548 - - 0.00000000000002088 75.0
CH2_k127_98893_2 Hemerythrin HHE cation binding domain - - - 0.000000000001478 73.0
CH2_k127_9917881_0 Histidine kinase K03320,K03406,K03407,K07315 - 2.7.13.3,3.1.3.3 0.0 1458.0
CH2_k127_9917881_1 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 419.0
CH2_k127_9922797_0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003711 239.0
CH2_k127_9922797_1 Polycystin cation channel K08714 - - 0.0000000000000000000000000000000000000000000000000000000000001931 218.0
CH2_k127_9922797_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000001256 195.0
CH2_k127_9922797_3 - - - - 0.0000000000000000000000000006349 116.0
CH2_k127_9922797_4 Protein of unknown function (DUF433) - - - 0.0000000000000000000000004275 108.0
CH2_k127_9922797_6 - - - - 0.0001268 44.0