Overview

ID MAG00264
Name CH2_bin.7
Sample SMP0008
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family UBA6910
Genus UBA6910
Species
Assembly information
Completeness (%) 60.59
Contamination (%) 1.9
GC content (%) 68.0
N50 (bp) 3,999
Genome size (bp) 1,927,070

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2181

Gene name Description KEGG GOs EC E-value Score Sequence
CH2_k127_10134967_0 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001153 239.0
CH2_k127_10134967_1 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000000001097 124.0
CH2_k127_10134967_2 PGAP1-like protein - - - 0.0000000000003743 73.0
CH2_k127_10167743_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 9.028e-319 990.0
CH2_k127_10167743_1 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 492.0
CH2_k127_10167743_2 His Kinase A (phospho-acceptor) domain K02484,K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 420.0
CH2_k127_10167743_3 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 338.0
CH2_k127_10167743_4 Iron-containing redox enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 305.0
CH2_k127_10167743_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000009373 228.0
CH2_k127_10167743_6 Thermostable hemolysin - - - 0.00000000000000000000000000000000000000000003602 169.0
CH2_k127_10167743_7 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000003912 162.0
CH2_k127_10167743_8 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000001878 135.0
CH2_k127_10167743_9 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000004625 66.0
CH2_k127_10270206_0 PLD-like domain K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 491.0
CH2_k127_10270206_1 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000599 190.0
CH2_k127_1027577_0 protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 354.0
CH2_k127_1027577_1 - - - - 0.00000000001109 72.0
CH2_k127_10311247_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 2.616e-209 659.0
CH2_k127_10311247_1 Poly-beta-hydroxybutyrate K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 578.0
CH2_k127_10322632_0 Glycosyltransferase 36 associated - - - 0.0 1365.0
CH2_k127_10322632_1 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 330.0
CH2_k127_10322632_2 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 300.0
CH2_k127_10325519_0 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 393.0
CH2_k127_10325519_1 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 356.0
CH2_k127_10325519_2 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 283.0
CH2_k127_10325519_3 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000008424 184.0
CH2_k127_10325519_4 lipid carrier protein - - - 0.00000000000000000000000000000000000001625 150.0
CH2_k127_10325519_5 - - - - 0.000006007 51.0
CH2_k127_10328994_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 9.542e-244 766.0
CH2_k127_10328994_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004411 263.0
CH2_k127_10328994_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000119 135.0
CH2_k127_10328994_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000009997 135.0
CH2_k127_10328994_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000694 122.0
CH2_k127_10338227_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 396.0
CH2_k127_10338227_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 338.0
CH2_k127_10338227_2 - - - - 0.000000000000000000000000000000000002166 150.0
CH2_k127_10338227_3 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00001949 54.0
CH2_k127_10342194_0 Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 301.0
CH2_k127_10342194_1 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.000000000008372 76.0
CH2_k127_10342194_2 Phosphotransferase enzyme family - - - 0.0000000002661 71.0
CH2_k127_10356019_0 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 590.0
CH2_k127_10356019_1 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000004151 228.0
CH2_k127_10356019_2 DnaJ domain - - - 0.00003431 51.0
CH2_k127_10367799_0 Glycosyl transferase family 41 - - - 1.576e-261 820.0
CH2_k127_10367799_1 single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000906 353.0
CH2_k127_10367799_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000001835 209.0
CH2_k127_10367799_3 VanZ like family - - - 0.000000000000000000000000000000000000003816 160.0
CH2_k127_10369843_0 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 414.0
CH2_k127_10369843_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000001013 145.0
CH2_k127_10377052_0 carbohydrate binding - - - 0.0 1390.0
CH2_k127_10393473_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 447.0
CH2_k127_10393473_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 308.0
CH2_k127_10393473_2 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004056 274.0
CH2_k127_10393473_3 chain 5 L K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000006231 175.0
CH2_k127_10393473_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000001266 166.0
CH2_k127_10402715_0 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000142 256.0
CH2_k127_10402715_1 Belongs to the Fur family K09826 - - 0.000000000000000000000000000000000005926 138.0
CH2_k127_10402715_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000003568 139.0
CH2_k127_10409765_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 593.0
CH2_k127_10409765_1 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 465.0
CH2_k127_10409765_2 Divalent cation transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 422.0
CH2_k127_10409765_3 - - - - 0.000000000000000000000000000000000000000003659 156.0
CH2_k127_10423218_0 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007797 281.0
CH2_k127_10423218_1 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 0.000000000000000000000000000001717 121.0
CH2_k127_1043425_0 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 334.0
CH2_k127_1043425_1 oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003251 261.0
CH2_k127_1043425_2 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000000004741 180.0
CH2_k127_10497994_0 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 401.0
CH2_k127_10497994_1 Periplasmic solute binding protein K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 383.0
CH2_k127_10497994_2 ABC 3 transport family - - - 0.00000000000000000001773 98.0
CH2_k127_1054021_0 PFAM Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 595.0
CH2_k127_1054021_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 393.0
CH2_k127_10547987_0 AsmA family K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 574.0
CH2_k127_10547987_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 535.0
CH2_k127_10547987_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001502 274.0
CH2_k127_10547987_3 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000000000000003163 86.0
CH2_k127_10565060_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 608.0
CH2_k127_10565060_1 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000703 215.0
CH2_k127_10571553_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 473.0
CH2_k127_10571553_1 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 436.0
CH2_k127_10571553_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000002739 202.0
CH2_k127_10579977_0 surface antigen K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 460.0
CH2_k127_10579977_1 protein conserved in bacteria K09800 - - 0.00000002158 65.0
CH2_k127_105846_0 Periplasmic copper-binding protein (NosD) K07218 - - 1.022e-213 674.0
CH2_k127_105846_1 ABC-2 family transporter protein K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 427.0
CH2_k127_105846_2 AAA domain, putative AbiEii toxin, Type IV TA system K19340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 403.0
CH2_k127_105846_3 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 409.0
CH2_k127_105846_4 NosL K19342 - - 0.0000000000000000000000000000000000000000000000000000000000000005192 231.0
CH2_k127_105846_5 oxidase assembly K02258 - - 0.000000000000000000000000000000000000000000000002791 182.0
CH2_k127_105846_6 - - - - 0.000000000000000000000000000000006561 135.0
CH2_k127_105846_7 domain, Protein - - - 0.00000000000000000000000000000001082 128.0
CH2_k127_105846_8 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000001308 121.0
CH2_k127_105846_9 - - - - 0.0000000000000000000000001505 109.0
CH2_k127_10591999_0 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 502.0
CH2_k127_10591999_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.00000000000000000006547 90.0
CH2_k127_10600621_0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000001114 236.0
CH2_k127_10600621_1 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000019 156.0
CH2_k127_10600621_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00006493 48.0
CH2_k127_1061084_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 592.0
CH2_k127_1061084_1 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 282.0
CH2_k127_10631830_0 Multicopper oxidase K22349 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 383.0
CH2_k127_10729566_0 Sulphur oxidation protein SoxZ K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 348.0
CH2_k127_10729566_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000003368 222.0
CH2_k127_10729566_2 24 kD subunit K00122 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000001274 207.0
CH2_k127_10729566_3 - - - - 0.00000000000000000000000000003864 120.0
CH2_k127_10729566_4 Metallo-beta-lactamase superfamily - - - 0.000000001334 58.0
CH2_k127_10762408_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 554.0
CH2_k127_10762408_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 407.0
CH2_k127_10762408_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000005247 185.0
CH2_k127_10764586_0 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 471.0
CH2_k127_10764586_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 413.0
CH2_k127_10797884_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 353.0
CH2_k127_10797884_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 314.0
CH2_k127_10797884_2 Glycine-zipper domain - - - 0.00000000000000000000000000000000000000000009747 165.0
CH2_k127_10797884_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000001659 152.0
CH2_k127_10797884_4 - - - - 0.0000000000000000000001089 99.0
CH2_k127_10797884_5 - - - - 0.0000000000000000000002321 102.0
CH2_k127_10797884_6 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000001626 53.0
CH2_k127_10815338_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 413.0
CH2_k127_10815338_1 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000005377 202.0
CH2_k127_10815338_2 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000000000005928 163.0
CH2_k127_10818879_0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 317.0
CH2_k127_10818879_1 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002745 276.0
CH2_k127_10818879_2 - - - - 0.000000000000000000000000005198 111.0
CH2_k127_10818879_3 - - - - 0.00001962 51.0
CH2_k127_10844481_0 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001835 281.0
CH2_k127_10844481_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000001979 256.0
CH2_k127_10844481_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000001502 119.0
CH2_k127_10855937_0 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 550.0
CH2_k127_10855937_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000005364 231.0
CH2_k127_10855937_2 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000001603 224.0
CH2_k127_10855937_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000000000000000000000000000000000000002112 157.0
CH2_k127_10861194_0 histidine kinase HAMP region domain protein K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 391.0
CH2_k127_10861194_1 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 302.0
CH2_k127_10861194_2 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000003676 236.0
CH2_k127_10861194_3 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000000000000002835 165.0
CH2_k127_10861194_4 PFAM Di-haem cytochrome c - - - 0.0000000000000000000000000000000000000000002223 170.0
CH2_k127_10931361_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 594.0
CH2_k127_10931361_1 Tim44 - - - 0.0000000000000000000000000000000000000000489 155.0
CH2_k127_10931361_2 protein conserved in bacteria K03690 - - 0.0000000000000000000000000000000000003433 151.0
CH2_k127_10940035_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 508.0
CH2_k127_10940035_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 312.0
CH2_k127_10940035_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 306.0
CH2_k127_10940035_3 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000006485 120.0
CH2_k127_10957481_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 470.0
CH2_k127_10957481_1 (Lipo)protein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 434.0
CH2_k127_10957481_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 343.0
CH2_k127_10957481_3 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000001279 214.0
CH2_k127_10957481_4 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.00000000000000000000000000000000000000000000001571 179.0
CH2_k127_10957481_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000004228 156.0
CH2_k127_109618_0 LysR substrate binding domain K13635 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 491.0
CH2_k127_109618_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 441.0
CH2_k127_109618_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000001263 183.0
CH2_k127_10981763_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008324 276.0
CH2_k127_10981763_1 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000001176 261.0
CH2_k127_11061880_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 527.0
CH2_k127_11061880_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 474.0
CH2_k127_11061880_2 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 478.0
CH2_k127_11061880_3 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 460.0
CH2_k127_11061880_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 361.0
CH2_k127_11061880_5 Alpha beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 286.0
CH2_k127_11068385_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 583.0
CH2_k127_11068385_1 ABC transporter K02013 - 3.6.3.34 0.00000000000001558 74.0
CH2_k127_11074219_0 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 406.0
CH2_k127_11074219_1 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002154 268.0
CH2_k127_11074219_2 CNP1-like family - - - 0.000000000000000000000000000000000000000000004806 172.0
CH2_k127_11074219_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000004266 150.0
CH2_k127_11074219_4 Protein of unknown function (DUF3617) - - - 0.0000000000000001393 86.0
CH2_k127_11082016_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000973 265.0
CH2_k127_11102665_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 615.0
CH2_k127_11102665_1 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 552.0
CH2_k127_11102665_2 - - - - 0.0000000000000000000000000000000003852 139.0
CH2_k127_11250405_0 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 443.0
CH2_k127_11250405_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000002122 242.0
CH2_k127_11250405_2 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000000000003496 148.0
CH2_k127_11250405_3 Protein of unknown function (DUF493) K09158 - - 0.0000000000000000000000000000001909 124.0
CH2_k127_11268183_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 431.0
CH2_k127_11268183_1 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 422.0
CH2_k127_11268183_2 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.000000000000000000000000000000001526 129.0
CH2_k127_11273666_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006143 264.0
CH2_k127_11273666_1 FAD linked oxidase - - - 0.0003668 48.0
CH2_k127_11285823_0 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 428.0
CH2_k127_11285823_1 Protein of unknown function, DUF480 K09915 - - 0.000000000000000000000000000000000000000001384 160.0
CH2_k127_11285823_2 ABC transporter, ATP-binding protein K11963 - - 0.00000000000000000000000000005673 116.0
CH2_k127_11298931_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 2.306e-197 620.0
CH2_k127_11298931_1 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 511.0
CH2_k127_11298931_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000181 229.0
CH2_k127_11298931_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0009165 42.0
CH2_k127_11298995_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000989 494.0
CH2_k127_11298995_1 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 320.0
CH2_k127_11298995_2 4-hydroxybenzoyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000000001314 166.0
CH2_k127_11307760_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 386.0
CH2_k127_11307760_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000004693 204.0
CH2_k127_11331243_0 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 424.0
CH2_k127_11331243_1 Hsp20/alpha crystallin family - - - 0.000000000000000000000000000000000000000000000004601 181.0
CH2_k127_11331243_2 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000000000000000001032 150.0
CH2_k127_11331243_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000009039 106.0
CH2_k127_11331243_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000002127 71.0
CH2_k127_11342463_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 2.413e-214 674.0
CH2_k127_11342463_1 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000018 117.0
CH2_k127_11345801_0 Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000004196 190.0
CH2_k127_11345801_1 TOBE domain K10112 - - 0.0000000000000000009383 96.0
CH2_k127_11347430_0 Part of the ABC transporter complex SsuABC involved in aliphatic sulfonates import. Responsible for energy coupling to the transport system K02049,K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 325.0
CH2_k127_11347430_1 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000003412 210.0
CH2_k127_11347430_2 OsmC-like protein - - - 0.000000000000000000000000000000000000000000582 159.0
CH2_k127_11375638_0 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 345.0
CH2_k127_11375638_1 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000001073 200.0
CH2_k127_11375638_2 nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein K00381,K00392 - 1.8.1.2,1.8.7.1 0.0000000000000000000000000000000000000000008238 163.0
CH2_k127_11414915_0 NiFe/NiFeSe hydrogenase small subunit C-terminal K00534 - 1.12.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 509.0
CH2_k127_11414915_1 Bacterial regulatory protein, Fis family K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008895 261.0
CH2_k127_11414915_2 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000000000000000000004704 162.0
CH2_k127_11428932_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 404.0
CH2_k127_11428932_1 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000001348 190.0
CH2_k127_11428932_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000000000000005819 144.0
CH2_k127_11428932_3 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000008832 128.0
CH2_k127_11434097_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 4.89e-225 704.0
CH2_k127_11434097_1 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 337.0
CH2_k127_11434097_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 293.0
CH2_k127_11434097_3 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000001626 229.0
CH2_k127_11434097_4 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000003101 211.0
CH2_k127_11434097_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000000001932 201.0
CH2_k127_11434097_6 Ribosomal protein S18 K02963 - - 0.000000000000000000000000000000000006296 138.0
CH2_k127_11434097_7 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000000000001911 102.0
CH2_k127_114468_0 PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 393.0
CH2_k127_11473629_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.974e-214 677.0
CH2_k127_11473629_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000001303 107.0
CH2_k127_11473629_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00002083 47.0
CH2_k127_11495914_0 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 505.0
CH2_k127_11495914_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 466.0
CH2_k127_11495914_3 Cytochrome P460 - - - 0.0000000000000000000000000000002315 127.0
CH2_k127_1151398_0 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 359.0
CH2_k127_1151398_1 ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 340.0
CH2_k127_1151398_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000001598 203.0
CH2_k127_1151398_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000001185 188.0
CH2_k127_1151398_4 regulation of ryanodine-sensitive calcium-release channel activity - - - 0.0000000000000001271 93.0
CH2_k127_11524750_0 - - - - 0.000000000000000000000000000008365 121.0
CH2_k127_11524750_1 - - - - 0.000000000000000004703 92.0
CH2_k127_11524750_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000003857 87.0
CH2_k127_11524750_3 Protein of unknown function (DUF3750) - - - 0.0000000000002486 69.0
CH2_k127_11558811_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 601.0
CH2_k127_11558811_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 338.0
CH2_k127_11558811_2 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000006794 184.0
CH2_k127_11558962_0 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 385.0
CH2_k127_11558962_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 313.0
CH2_k127_11558962_2 Protein of unknown function (DUF3302) - - - 0.000000000000000000000000000000000000005946 152.0
CH2_k127_11626176_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 371.0
CH2_k127_11626176_1 tRNA rRNA methyltransferase, SpoU K03437 - - 0.0000000000000000000000000000000000000000000000000000000000008849 231.0
CH2_k127_11626176_2 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000001375 61.0
CH2_k127_1165238_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 9.476e-194 610.0
CH2_k127_1165238_1 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 480.0
CH2_k127_1165238_2 Glycosyl transferase group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009267 270.0
CH2_k127_1165238_3 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001324 280.0
CH2_k127_1165238_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000008373 195.0
CH2_k127_1165238_5 Protein of unknown function (DUF3047) - - - 0.0001138 53.0
CH2_k127_11705568_0 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 329.0
CH2_k127_11705568_1 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 304.0
CH2_k127_11710797_0 pdz dhr glgf - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 393.0
CH2_k127_11710797_1 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 302.0
CH2_k127_11717342_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1011.0
CH2_k127_11717342_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 2.27e-322 994.0
CH2_k127_11717342_2 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 410.0
CH2_k127_11717342_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007168 308.0
CH2_k127_11717342_4 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005639 283.0
CH2_k127_11717342_5 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000005888 239.0
CH2_k127_11725564_0 transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 489.0
CH2_k127_11725564_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000122 262.0
CH2_k127_11725564_2 ABC transporter K01990 - - 0.000158 45.0
CH2_k127_11726361_0 Transmembrane secretion effector - - - 2.246e-247 777.0
CH2_k127_11726361_1 Pseudouridine synthase K06175 - 5.4.99.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 342.0
CH2_k127_11726361_2 - - - - 0.000007923 49.0
CH2_k127_11764425_0 PFAM 17 kDa surface antigen - - - 0.0000000000000000000000000000000000002225 149.0
CH2_k127_11764425_1 Protein of unknown function (DUF3568) - - - 0.00000000000000000000000000002271 123.0
CH2_k127_11764425_2 - - - - 0.00000000000000000002359 104.0
CH2_k127_11764425_3 Belongs to the UPF0337 (CsbD) family - - - 0.000002042 53.0
CH2_k127_11798161_0 Malic enzyme K00029 - 1.1.1.40 0.0 1022.0
CH2_k127_11798161_1 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005104 246.0
CH2_k127_11815692_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 436.0
CH2_k127_11815692_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002847 277.0
CH2_k127_11815692_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005289 250.0
CH2_k127_11818259_0 Acetoacetyl-CoA synthase K01907 - 6.2.1.16 7.591e-257 798.0
CH2_k127_11818259_1 - - - - 0.000000000000000000000000000009659 125.0
CH2_k127_11818259_2 YMGG-like Gly-zipper - - - 0.00000000000000009005 81.0
CH2_k127_11836459_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 490.0
CH2_k127_11836459_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 286.0
CH2_k127_11836459_2 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.000000000002134 75.0
CH2_k127_1183764_0 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000000000000000000000000000002486 214.0
CH2_k127_1183764_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000006783 176.0
CH2_k127_11851452_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.575e-203 637.0
CH2_k127_11851452_1 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 381.0
CH2_k127_11851452_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 377.0
CH2_k127_11851452_3 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0000000000000000161 82.0
CH2_k127_1195450_0 Cache 3/Cache 2 fusion domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 461.0
CH2_k127_1195450_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000007874 214.0
CH2_k127_11990171_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 428.0
CH2_k127_11990171_1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 414.0
CH2_k127_11990171_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000201 256.0
CH2_k127_11990171_3 Protein of unknown function (DUF1318) K09978 - - 0.00000000000000000000000000000000000000000000000000000003858 198.0
CH2_k127_11990171_4 - - - - 0.00000000008665 66.0
CH2_k127_1203332_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.477e-227 712.0
CH2_k127_1203332_1 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000008049 265.0
CH2_k127_1203332_2 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000005244 216.0
CH2_k127_1203332_3 esterase K07000 - - 0.0000000000000000000000000000000000000000000000000009863 206.0
CH2_k127_1203332_4 PFAM Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000006707 179.0
CH2_k127_1203332_5 ribonuclease II K01147 - 3.1.13.1 0.0000000000000000000001426 98.0
CH2_k127_1203332_6 Protein of unknown function (DUF3568) - - - 0.00001963 47.0
CH2_k127_12045137_0 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 438.0
CH2_k127_12045137_1 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 299.0
CH2_k127_12105932_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 476.0
CH2_k127_12105932_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000001919 207.0
CH2_k127_12105932_2 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000004145 147.0
CH2_k127_121108_0 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 454.0
CH2_k127_121108_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 345.0
CH2_k127_121108_2 peptidase C26 K01658,K07010 - 4.1.3.27 0.00000000000000000000000000000000000001059 146.0
CH2_k127_12116328_0 PFAM LrgB family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 304.0
CH2_k127_12116328_1 effector of murein hydrolase LrgA K06518 - - 0.00000000000000000000000000000001087 130.0
CH2_k127_12116328_2 Transport permease protein K01992 - - 0.00000000000000000000000000000007985 127.0
CH2_k127_12116328_3 Phasin protein - - - 0.00000000000000003236 88.0
CH2_k127_12183126_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1061.0
CH2_k127_12183126_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 4.006e-233 726.0
CH2_k127_12183126_2 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000547 533.0
CH2_k127_12183126_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 518.0
CH2_k127_12183126_4 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 464.0
CH2_k127_12183126_5 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 405.0
CH2_k127_12183126_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 299.0
CH2_k127_12183126_7 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000001248 141.0
CH2_k127_12183126_8 protein conserved in bacteria K09937 - - 0.000000000000000000002853 95.0
CH2_k127_12191433_0 associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 535.0
CH2_k127_12191433_1 Putative metallopeptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 370.0
CH2_k127_12191433_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 321.0
CH2_k127_12191433_3 - - - - 0.0000000000000000000000000000038 131.0
CH2_k127_12197096_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.17e-207 655.0
CH2_k127_12197096_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004935 279.0
CH2_k127_12197096_2 Thioredoxin K05838 - - 0.00000000000000000000000000000000000000000000000000000000000005021 219.0
CH2_k127_12206759_0 Transposase K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 415.0
CH2_k127_12206759_1 IS66 Orf2 like protein - - - 0.0000000000000000000000000009371 117.0
CH2_k127_12206759_2 Trypsin-like peptidase domain - - - 0.000000000000166 79.0
CH2_k127_12206759_4 Transposase IS116/IS110/IS902 family - - - 0.0000315 50.0
CH2_k127_12238772_0 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 7.57e-214 669.0
CH2_k127_12238772_1 CoA-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 557.0
CH2_k127_12238772_2 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 517.0
CH2_k127_12238772_3 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 355.0
CH2_k127_12238772_4 Pfam cytochrome c K17230 - - 0.00000000000000000000000000000000000000003082 164.0
CH2_k127_12247990_0 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000004385 201.0
CH2_k127_12247990_1 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000948 211.0
CH2_k127_12247990_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000002636 200.0
CH2_k127_12247990_3 TPR repeat - - - 0.00000000000000000000000000000000000000006413 154.0
CH2_k127_12247990_4 LysR family K04761 - - 0.000000000000000000000000000000000000000388 153.0
CH2_k127_12272730_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 1.752e-250 781.0
CH2_k127_12272730_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 481.0
CH2_k127_12272730_2 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 377.0
CH2_k127_12272730_3 KAP family P-loop domain - - - 0.00000000000000000000000000000000000000000000000003069 207.0
CH2_k127_12272730_4 PGAP1-like protein - - - 0.0000000000000000000000000000000000000001547 162.0
CH2_k127_12272730_5 monooxygenase activity - - - 0.0000000000000000000000000000000000008347 146.0
CH2_k127_12272730_6 D-alanyl-D-alanine carboxypeptidase K17733 - - 0.00000008442 67.0
CH2_k127_12362662_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 580.0
CH2_k127_12362662_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 345.0
CH2_k127_12362662_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002032 239.0
CH2_k127_12362662_3 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000006393 126.0
CH2_k127_12416371_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 364.0
CH2_k127_12416371_1 Molybdenum Cofactor Synthesis C K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 356.0
CH2_k127_12416371_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000003703 122.0
CH2_k127_12428350_0 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 499.0
CH2_k127_12428350_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 473.0
CH2_k127_12428350_2 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004387 250.0
CH2_k127_12428350_3 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000000000000004301 167.0
CH2_k127_12428350_4 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000000000000000000000000009853 132.0
CH2_k127_12454115_0 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 445.0
CH2_k127_12454115_1 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000006534 235.0
CH2_k127_12454115_2 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000001245 127.0
CH2_k127_12454115_3 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000016 103.0
CH2_k127_12454115_4 rieske 2fe-2s - - - 0.0000000000000000001326 89.0
CH2_k127_124549_0 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 482.0
CH2_k127_124549_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000001202 190.0
CH2_k127_12498790_0 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 5.934e-227 717.0
CH2_k127_12498790_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 323.0
CH2_k127_12498790_2 Trypsin Inhibitor like cysteine rich domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0009594 44.0
CH2_k127_12516973_0 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 498.0
CH2_k127_12516973_1 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 312.0
CH2_k127_12516973_2 carboxyl transferase K01969 - 6.4.1.4 0.000000000000000000009217 91.0
CH2_k127_12544349_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 589.0
CH2_k127_12544349_1 phosphohistidine phosphatase, SixA - - - 0.0000000000000000867 89.0
CH2_k127_12544349_2 homoserine kinase activity - - - 0.0000000008489 71.0
CH2_k127_12544349_3 RimK-like ATP-grasp domain K05844 - - 0.000002625 60.0
CH2_k127_12621634_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 7.33e-249 773.0
CH2_k127_12621634_1 Acts as a magnesium transporter K06213 - - 1.002e-209 661.0
CH2_k127_12621634_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000002025 201.0
CH2_k127_12621634_3 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000001113 117.0
CH2_k127_12637025_0 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 3.747e-203 650.0
CH2_k127_12637025_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 429.0
CH2_k127_12637025_2 PFAM Zinc iron permease K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 368.0
CH2_k127_12637025_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 319.0
CH2_k127_12637025_4 synthesis repressor, PhaR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009403 257.0
CH2_k127_12637025_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000006917 187.0
CH2_k127_12637025_6 Phasin protein - - - 0.00000000000000000000000000000000003337 141.0
CH2_k127_12637025_7 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000004973 132.0
CH2_k127_12637025_8 - - - - 0.000000274 56.0
CH2_k127_12637678_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 588.0
CH2_k127_12637678_1 4Fe-4S single cluster domain K18006 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 360.0
CH2_k127_12637678_2 NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.00000000000000000002505 92.0
CH2_k127_12651549_0 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 525.0
CH2_k127_12651549_1 Mycolic acid cyclopropane synthetase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008724 462.0
CH2_k127_12651549_2 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 398.0
CH2_k127_12651549_3 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 330.0
CH2_k127_12651549_4 B12 binding domain K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 290.0
CH2_k127_12651549_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000001995 243.0
CH2_k127_12651549_6 Protein of unknown function (DUF3833) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007332 257.0
CH2_k127_12651549_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000005017 154.0
CH2_k127_12651549_8 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000302 154.0
CH2_k127_12654443_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1422.0
CH2_k127_12654443_1 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001924 246.0
CH2_k127_12654443_2 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000426 154.0
CH2_k127_12667403_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239 - - 0.0 1606.0
CH2_k127_12667403_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 7.679e-218 687.0
CH2_k127_12667403_2 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 471.0
CH2_k127_12667403_3 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005408 244.0
CH2_k127_12667403_4 EamA-like transporter family - - - 0.000000000000000000000000000000003533 134.0
CH2_k127_12667403_5 - - - - 0.000000000000000000003494 99.0
CH2_k127_12667403_6 - - - - 0.0000000000000009758 81.0
CH2_k127_12673374_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 545.0
CH2_k127_12673374_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 404.0
CH2_k127_12673374_10 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000001413 158.0
CH2_k127_12673374_11 Tautomerase enzyme K01821 - 5.3.2.6 0.000000000000000000000000002081 111.0
CH2_k127_12673374_12 Domain of unknown function (DUF4845) - - - 0.0000000000000003239 85.0
CH2_k127_12673374_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 403.0
CH2_k127_12673374_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 391.0
CH2_k127_12673374_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 349.0
CH2_k127_12673374_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 313.0
CH2_k127_12673374_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 296.0
CH2_k127_12673374_7 Uracil DNA glycosylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 293.0
CH2_k127_12673374_8 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 289.0
CH2_k127_12673374_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000008366 266.0
CH2_k127_12705990_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 497.0
CH2_k127_12705990_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000436 160.0
CH2_k127_12718834_0 Haloacid dehalogenase-like hydrolase K20881 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 299.0
CH2_k127_12718834_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000006836 199.0
CH2_k127_12718834_2 ATP-binding region, ATPase domain protein domain protein - - - 0.0000000001909 73.0
CH2_k127_12754009_0 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 437.0
CH2_k127_12754009_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000001404 239.0
CH2_k127_12754009_2 Bacterial transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000002984 191.0
CH2_k127_12754009_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000005135 164.0
CH2_k127_12754009_4 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000002167 145.0
CH2_k127_12835616_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 1.757e-197 620.0
CH2_k127_12835616_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 520.0
CH2_k127_12835616_2 pilus assembly protein FimV K08086 - - 0.000000000000000000000000000000000006507 141.0
CH2_k127_12837332_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 2.106e-246 769.0
CH2_k127_12837332_1 oxaloacetate decarboxylase activity K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 574.0
CH2_k127_12837332_10 COG1278 Cold shock proteins K03704 - - 0.00000000000000000000000005211 111.0
CH2_k127_12837332_11 CoA carboxylase activity K01965 - 6.4.1.3 0.00000000000000000000000007889 124.0
CH2_k127_12837332_12 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000007361 95.0
CH2_k127_12837332_13 Saccharopine dehydrogenase - - - 0.000000000000000004361 85.0
CH2_k127_12837332_2 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 549.0
CH2_k127_12837332_3 Bacterial periplasmic substrate-binding proteins K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 325.0
CH2_k127_12837332_4 Predicted methyltransferase regulatory domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000139 297.0
CH2_k127_12837332_5 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008647 286.0
CH2_k127_12837332_6 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001131 285.0
CH2_k127_12837332_7 Fasciclin - - - 0.000000000000000000000000000000000000000003296 162.0
CH2_k127_12837332_8 Translation initiation factor 1A / IF-1 K02518 - - 0.0000000000000000000000000000000000001534 143.0
CH2_k127_12837332_9 sodium ion export across plasma membrane K01573 GO:0003674,GO:0003824,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008948,GO:0015672,GO:0016829,GO:0016830,GO:0016831,GO:0030001,GO:0051179,GO:0051234 4.1.1.3 0.0000000000000000000000000001051 118.0
CH2_k127_12958080_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 4.32e-295 923.0
CH2_k127_12958080_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 403.0
CH2_k127_12958080_2 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 331.0
CH2_k127_12958080_3 Rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000107 158.0
CH2_k127_12961360_0 4Fe-4S dicluster domain - - - 3.628e-233 744.0
CH2_k127_12961360_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 568.0
CH2_k127_12961360_2 Chaperone protein TorD - - - 0.000000000000000000000000000000000000000005953 161.0
CH2_k127_12961360_3 Protein of unknown function (DUF3305) - - - 0.00000000000000000000000000000000004438 137.0
CH2_k127_12961360_4 Protein of unknown function (DUF3306) - - - 0.00000000000000000000000006805 117.0
CH2_k127_13030208_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 1.919e-235 742.0
CH2_k127_13030208_1 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 448.0
CH2_k127_13030208_2 PFAM Bacterial regulatory helix-turn-helix proteins, AraC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001641 273.0
CH2_k127_13030208_3 Predicted periplasmic protein (DUF2092) - - - 0.000000000000000000000000000000000000000000000000000000002323 210.0
CH2_k127_13030208_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000000000004769 145.0
CH2_k127_13030208_5 Protein of unknown function (DUF3313) - - - 0.00000000000000000000000000000003325 136.0
CH2_k127_13030208_7 - - - - 0.0000007615 54.0
CH2_k127_1325973_0 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 570.0
CH2_k127_1325973_1 transcriptional regulator, ArsR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 287.0
CH2_k127_1325973_2 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005043 249.0
CH2_k127_1355105_0 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 379.0
CH2_k127_1355105_1 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000006881 166.0
CH2_k127_1355105_2 Protein of unknown function (DUF971) - - - 0.0000000853 64.0
CH2_k127_1407351_0 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 358.0
CH2_k127_1407351_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002358 284.0
CH2_k127_1407351_2 DsrC like protein - - - 0.000000000000000000000000000000000000002346 149.0
CH2_k127_1407351_3 TraB family K09973 - - 0.00000000000000000000001451 105.0
CH2_k127_1408660_0 type II secretion system protein K02454 - - 8.541e-239 749.0
CH2_k127_1408660_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 413.0
CH2_k127_1408660_2 - - - - 0.000000000000000000000000000000000000000003089 166.0
CH2_k127_1408660_3 carbon utilization K02664,K02665 - - 0.000000000000000000000000000000006321 135.0
CH2_k127_1408660_4 - - - - 0.0000000000000000000000000002276 129.0
CH2_k127_1408660_5 conserved repeat domain protein - - - 0.0000000000000000002862 103.0
CH2_k127_1411402_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 541.0
CH2_k127_1411402_1 PFAM ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 435.0
CH2_k127_1411402_2 Domain of unknown function (DUF4124) - - - 0.000000000000000000000001022 111.0
CH2_k127_1411402_3 - - - - 0.0000000000000000005886 98.0
CH2_k127_1413964_0 Belongs to the TPP enzyme family K01608 - 4.1.1.47 4.594e-230 721.0
CH2_k127_1416680_0 Protein of unknown function (DUF3141) - - - 7.124e-264 823.0
CH2_k127_1416680_1 phosphate K00625 - 2.3.1.8 0.000000000000000000000000000000001551 131.0
CH2_k127_1428156_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 2.733e-278 864.0
CH2_k127_1428156_1 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 426.0
CH2_k127_1428156_2 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002384 257.0
CH2_k127_1443379_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004091 254.0
CH2_k127_1443379_1 - - - - 0.00000000000000000000000001877 117.0
CH2_k127_1472979_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 621.0
CH2_k127_1472979_1 CRP FNR family K21563 - - 0.000000000000000000000002314 104.0
CH2_k127_1506780_0 NAD(P) transhydrogenase, alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 404.0
CH2_k127_1506780_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 291.0
CH2_k127_1506780_2 4TM region of pyridine nucleotide transhydrogenase, mitoch K00322,K00324 - 1.6.1.1,1.6.1.2 0.000000000000000000000000000000000000001511 150.0
CH2_k127_150720_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 374.0
CH2_k127_150720_1 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000001244 154.0
CH2_k127_150720_2 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000006751 135.0
CH2_k127_150720_3 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000008342 115.0
CH2_k127_150720_4 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000004951 91.0
CH2_k127_1524382_0 TIGRFAM para-aminobenzoate synthase, subunit I K01665,K03342 - 2.6.1.85,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 510.0
CH2_k127_1611094_0 Major facilitator superfamily MFS_1 K02445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 550.0
CH2_k127_1611094_1 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 395.0
CH2_k127_1611094_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 329.0
CH2_k127_1611094_3 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.0000000000000000000000000000000002169 132.0
CH2_k127_1648518_0 epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 284.0
CH2_k127_1648518_1 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000008548 185.0
CH2_k127_1648518_2 Divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000005338 145.0
CH2_k127_1707612_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 378.0
CH2_k127_1707612_1 sulfide dehydrogenase K05301 - 1.8.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002904 266.0
CH2_k127_1707612_2 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000008716 151.0
CH2_k127_1707612_3 SpoIIAA-like - - - 0.0000000000000000000000000000008862 123.0
CH2_k127_1842139_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004266 276.0
CH2_k127_1842139_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002965 243.0
CH2_k127_1842139_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000006793 235.0
CH2_k127_1880248_0 von Willebrand factor (vWF) type A domain K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 607.0
CH2_k127_1880248_1 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000002938 226.0
CH2_k127_1882358_0 His Kinase A (phosphoacceptor) domain K19661 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 534.0
CH2_k127_1882358_1 High-affinity nickel-transport protein K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002472 278.0
CH2_k127_1882358_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000769 237.0
CH2_k127_1882358_3 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000002205 208.0
CH2_k127_1892883_0 Response regulator receiver K07714,K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 582.0
CH2_k127_1892883_1 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 518.0
CH2_k127_1892883_2 PFAM Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 386.0
CH2_k127_1892883_3 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003146 282.0
CH2_k127_1892883_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000002958 108.0
CH2_k127_1892883_5 - - - - 0.00000000000000000000001011 109.0
CH2_k127_1892883_6 ERAD pathway K07126,K14026 - - 0.00000001679 66.0
CH2_k127_1936850_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 400.0
CH2_k127_1936850_1 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 403.0
CH2_k127_1936850_2 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 360.0
CH2_k127_1945870_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 481.0
CH2_k127_1945870_1 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 419.0
CH2_k127_1945870_2 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 307.0
CH2_k127_1945870_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000000000000000000000000000000000000009362 152.0
CH2_k127_1945870_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000002002 82.0
CH2_k127_1971847_0 Molecular chaperone. Has ATPase activity K04079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 602.0
CH2_k127_1971847_1 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.00000000000000000000000000000000000000000000000000000000000000001814 224.0
CH2_k127_2015211_0 Sigma-54 interaction domain - - - 7.194e-209 672.0
CH2_k127_2015211_1 Belongs to the peptidase S8 family - - - 2.325e-197 652.0
CH2_k127_2015211_2 Flavoprotein - - - 0.00000000000000000000000000000000000782 142.0
CH2_k127_2015211_3 TIGRFAM para-aminobenzoate synthase, subunit I K01665,K03342 - 2.6.1.85,4.1.3.38 0.00000000000000000000000005837 109.0
CH2_k127_2015211_4 Protein of unknown function (DUF447) K09154 - - 0.00000000001838 64.0
CH2_k127_2044387_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 541.0
CH2_k127_2044387_1 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000001006 130.0
CH2_k127_2044387_2 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000001376 79.0
CH2_k127_2044387_3 AMP-binding enzyme C-terminal domain K18661 - - 0.00000000008027 65.0
CH2_k127_206783_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1093.0
CH2_k127_206783_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000706 317.0
CH2_k127_206783_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005838 263.0
CH2_k127_206783_3 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000003596 209.0
CH2_k127_206783_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000001938 167.0
CH2_k127_206783_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000001574 147.0
CH2_k127_2190610_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.562e-242 759.0
CH2_k127_2190610_1 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 372.0
CH2_k127_2190610_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000006558 209.0
CH2_k127_2195420_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 323.0
CH2_k127_2341355_0 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 295.0
CH2_k127_2341355_1 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000005045 187.0
CH2_k127_2341355_2 antiporter K07301 - - 0.00000000000000000531 85.0
CH2_k127_2349792_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 551.0
CH2_k127_2349792_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 366.0
CH2_k127_2349792_2 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 294.0
CH2_k127_2349792_3 - - - - 0.00000003902 57.0
CH2_k127_2353727_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 392.0
CH2_k127_2353727_1 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 380.0
CH2_k127_2353727_2 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000002367 117.0
CH2_k127_2384448_0 haloacid dehalogenase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 329.0
CH2_k127_2384448_1 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000008713 249.0
CH2_k127_2384448_2 Protein of unknown function (DUF3530) - - - 0.0000000000000000000000000000000000000000000000005958 187.0
CH2_k127_2393735_0 2-Nitropropane dioxygenase K00459 - 1.13.12.16 1.04e-218 684.0
CH2_k127_2393735_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 497.0
CH2_k127_2427368_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1087.0
CH2_k127_2427368_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 347.0
CH2_k127_2427368_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000001653 64.0
CH2_k127_2530780_0 homolog of phage Mu protein gp47 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 462.0
CH2_k127_2530780_1 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 408.0
CH2_k127_2530780_2 Late control gene D protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 379.0
CH2_k127_2530780_3 Baseplate assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 304.0
CH2_k127_2530780_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001949 262.0
CH2_k127_2530780_5 Gene 25-like lysozyme K06903 - - 0.00000000000000000000000000000000004765 147.0
CH2_k127_2530780_6 - - - - 0.000000000000000000000004691 104.0
CH2_k127_2579464_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 563.0
CH2_k127_2579464_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000002196 213.0
CH2_k127_257978_0 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 443.0
CH2_k127_257978_1 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 336.0
CH2_k127_257978_2 - - - - 0.000000000000000000008488 98.0
CH2_k127_258519_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004762 510.0
CH2_k127_258519_1 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 471.0
CH2_k127_258519_2 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000001896 184.0
CH2_k127_258519_3 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000708 144.0
CH2_k127_2602463_0 transporter component K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 368.0
CH2_k127_2602463_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 329.0
CH2_k127_2602463_2 4Fe-4S single cluster domain K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 318.0
CH2_k127_2602463_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000003712 153.0
CH2_k127_2613376_0 Mandelate Racemase Muconate Lactonizing K01781,K20023,K20549 - 4.2.1.156,4.2.1.42,5.1.2.2,5.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 506.0
CH2_k127_2613376_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 357.0
CH2_k127_2613376_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 303.0
CH2_k127_2613376_3 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001036 267.0
CH2_k127_2613376_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002555 258.0
CH2_k127_2613376_5 2-Keto-4-pentenoate hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005289 250.0
CH2_k127_2613376_6 Predicted membrane protein (DUF2306) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005192 252.0
CH2_k127_2613376_7 Domain of unknown function (DUF2703) - - - 0.00000000000000000000000000000000000000000001429 166.0
CH2_k127_2664784_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 590.0
CH2_k127_2664784_1 Protein of unknown function (DUF2863) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 432.0
CH2_k127_2664784_2 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001414 266.0
CH2_k127_2664784_3 YCII-related domain K09780 - - 0.000000000000000000000000000000000000000000008602 174.0
CH2_k127_2664784_4 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000000003066 115.0
CH2_k127_2664784_5 Peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.00003424 53.0
CH2_k127_2710006_0 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 2.323e-219 681.0
CH2_k127_2710006_1 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 2.143e-214 676.0
CH2_k127_2710006_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009194 353.0
CH2_k127_2710006_3 Sulfurtransferase TusA - - - 0.000000000000000000000000000000000000000000000000000000001452 204.0
CH2_k127_2710006_4 sulfur relay protein TusD DsrE K07235 - - 0.00000000000000000000000000000000000000000000000000000003575 215.0
CH2_k127_2710006_5 Cas6 Crispr - - - 0.0000000000000000000000000000000000000000000000000006653 191.0
CH2_k127_2710006_6 DsrC like protein - - - 0.00000000000000000000000000000000000000000002713 166.0
CH2_k127_2710006_7 Sulfur relay protein TusC DsrF K07236 - - 0.00000000000000000000000000000000000000000003487 168.0
CH2_k127_2710006_8 - - - - 0.0000000000000000000000000000001091 130.0
CH2_k127_2710006_9 - - - - 0.0000000000000000000002259 98.0
CH2_k127_2711592_0 Branched-chain amino acid transport system / permease component K11960 - - 1.55e-207 660.0
CH2_k127_2711592_1 Branched-chain amino acid transport system / permease component K11961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 550.0
CH2_k127_2711592_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K11959 - - 0.0000000000000000000000000000000000000000000000000000004133 193.0
CH2_k127_271577_0 TonB dependent receptor - - - 6.052e-223 717.0
CH2_k127_271577_1 Transcriptional activator of acetoin glycerol metabolism K21405 - - 1.146e-194 627.0
CH2_k127_271577_2 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 390.0
CH2_k127_271577_3 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005378 279.0
CH2_k127_271577_4 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001072 252.0
CH2_k127_271577_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000003111 205.0
CH2_k127_271577_6 Cytochrome b/b6/petB - - - 0.00000000000000000000000000000000000000000000000002212 184.0
CH2_k127_271577_7 Histidine kinase - - - 0.0000000000000000000000000000009128 126.0
CH2_k127_2778287_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 598.0
CH2_k127_2778287_1 dehydrogenase reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 327.0
CH2_k127_2778287_2 - - - - 0.000000000000000000000000000000000000000000000000001484 185.0
CH2_k127_2778287_3 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.0000000000000000000000000000000002347 134.0
CH2_k127_2778287_4 Thioesterase superfamily K07107 - - 0.000000000000000000000000000000002487 149.0
CH2_k127_2778287_5 - - - - 0.0000000000000000000000007696 112.0
CH2_k127_2824771_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 454.0
CH2_k127_2824771_1 - - - - 0.000000000000000000000000000000000000000000000000000000000001231 218.0
CH2_k127_2824771_2 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000001572 173.0
CH2_k127_2824771_3 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000000000000000000000002697 169.0
CH2_k127_2824771_4 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000004776 153.0
CH2_k127_2824771_5 Outer Membrane Lipoprotein K06077 - - 0.00000000000003885 80.0
CH2_k127_2825293_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 561.0
CH2_k127_2825293_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000001282 205.0
CH2_k127_2825293_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000001269 101.0
CH2_k127_2829232_0 SurA N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001306 278.0
CH2_k127_2829232_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000002267 150.0
CH2_k127_2854444_0 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 507.0
CH2_k127_2854444_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 389.0
CH2_k127_2854444_2 PFAM Glutamine amidotransferase, class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 375.0
CH2_k127_2854444_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002157 292.0
CH2_k127_2855558_0 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 396.0
CH2_k127_2855558_1 Protein conserved in bacteria K04750 - - 0.0000000000000000000000000000000000000000000000000000000000001695 216.0
CH2_k127_2855558_2 - - - - 0.000000000000000000000000000000000000000000000000000000000001813 217.0
CH2_k127_2855558_3 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000001071 210.0
CH2_k127_2855558_4 - - - - 0.000000000000000000000000002763 118.0
CH2_k127_2879033_0 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 571.0
CH2_k127_2879033_1 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000004491 111.0
CH2_k127_2879033_2 - - - - 0.000000000000000001625 96.0
CH2_k127_2935965_0 Phage tail sheath C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 590.0
CH2_k127_2935965_1 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 297.0
CH2_k127_29493_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2016.0
CH2_k127_2958342_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 298.0
CH2_k127_2958342_1 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000001721 185.0
CH2_k127_2958342_2 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000002447 160.0
CH2_k127_2958342_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000000605 140.0
CH2_k127_2958342_4 Sulfurtransferase - - - 0.0000000000000000000000001151 108.0
CH2_k127_2958342_5 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000415 64.0
CH2_k127_2971361_0 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008386 282.0
CH2_k127_2971361_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000003109 166.0
CH2_k127_2971361_2 - - - - 0.000000000000000000000000000125 130.0
CH2_k127_2971361_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000005432 90.0
CH2_k127_3069681_0 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000339 260.0
CH2_k127_3069681_1 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.000000000000000000000000000000000000000000000000001695 183.0
CH2_k127_3069681_2 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.000000000000000006835 83.0
CH2_k127_3125200_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 463.0
CH2_k127_3125200_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 353.0
CH2_k127_3125200_2 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007344 334.0
CH2_k127_3125200_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000003719 201.0
CH2_k127_3125200_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000004533 55.0
CH2_k127_3134126_0 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 493.0
CH2_k127_3134126_1 PAP2 (Acid phosphatase) superfamily protein - - - 0.0000000000000000000000000000000000000000000000005908 182.0
CH2_k127_3134126_2 PFAM 17 kDa surface antigen K06077 - - 0.0000000000000000000000000000000000000000001103 165.0
CH2_k127_3134126_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000157 85.0
CH2_k127_322203_0 Trypsin K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 546.0
CH2_k127_322203_1 Cold-shock DNA-binding domain protein K03704 - - 0.000000000000000000000000000000006027 128.0
CH2_k127_322203_2 - - - - 0.000000000000000000000000000001541 125.0
CH2_k127_322203_3 Protein of unknown function (DUF3460) - - - 0.00000000000003623 74.0
CH2_k127_322203_4 Spermidine synthase K00797 - 2.5.1.16 0.000008596 49.0
CH2_k127_3234741_0 ABC transporter K15738 - - 1.189e-280 876.0
CH2_k127_3234741_1 Pfam Fatty acid - - - 5.955e-277 864.0
CH2_k127_3234741_2 Catalyzes the conversion of pppGpp to ppGpp. Guanosine pentaphosphate (pppGpp) is a cytoplasmic signaling molecule which together with ppGpp controls the stringent response , an adaptive process that allows bacteria to respond to amino acid starvation, resulting in the coordinated regulation of numerous cellular activities K01524 - 3.6.1.11,3.6.1.40 1.714e-218 687.0
CH2_k127_3234741_3 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 427.0
CH2_k127_3234741_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 394.0
CH2_k127_3234741_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002816 286.0
CH2_k127_3234741_6 triphosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003257 272.0
CH2_k127_3234741_7 Sodium Bile acid symporter family K03453 - - 0.0000000000000000000000000000000000000005479 160.0
CH2_k127_326696_0 SMART Elongator protein 3 MiaB NifB K09711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 489.0
CH2_k127_326696_1 lipoate-protein ligase A K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006874 452.0
CH2_k127_326696_2 DsrE/DsrF-like family K07092 - - 0.0000000000000000000000000000000000000000000001401 171.0
CH2_k127_326696_3 glycine decarboxylation via glycine cleavage system K02437 - - 0.000000000000000000000000000000000000132 153.0
CH2_k127_3276654_0 Competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 447.0
CH2_k127_3276654_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008479 283.0
CH2_k127_3276654_2 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000002545 242.0
CH2_k127_3276654_3 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000000000000000000000000000000004382 207.0
CH2_k127_3276896_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 605.0
CH2_k127_3276896_1 PFAM Endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000285 200.0
CH2_k127_3276896_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000008472 108.0
CH2_k127_3276896_3 - - - - 0.0001727 48.0
CH2_k127_3296112_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001404 279.0
CH2_k127_3296112_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009551 280.0
CH2_k127_3296112_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000774 258.0
CH2_k127_3296112_3 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000001946 189.0
CH2_k127_3296112_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000002276 142.0
CH2_k127_3324144_0 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 543.0
CH2_k127_3324144_1 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05577 - 1.6.5.3 0.00000000004805 64.0
CH2_k127_334202_0 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 331.0
CH2_k127_334202_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000001178 164.0
CH2_k127_334202_2 - - - - 0.000000000000000000000000000000001052 137.0
CH2_k127_3360888_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.32e-217 680.0
CH2_k127_3360888_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 369.0
CH2_k127_3360888_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000003355 238.0
CH2_k127_3363285_0 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 295.0
CH2_k127_3363285_1 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 285.0
CH2_k127_3363285_2 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000001558 166.0
CH2_k127_3374845_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 4.095e-236 734.0
CH2_k127_3374845_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 351.0
CH2_k127_3374845_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000012 136.0
CH2_k127_3405957_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000001067 240.0
CH2_k127_3405957_1 phosphinothricin N-acetyltransferase activity K09181 - - 0.0000000000000000000000000000000000004726 147.0
CH2_k127_3405957_2 PFAM Sporulation domain protein - - - 0.0000000000000000000000000000000000006681 148.0
CH2_k127_3405957_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.00000000000000000009419 89.0
CH2_k127_3405957_4 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000001054 54.0
CH2_k127_340967_0 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 - 3.5.4.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 452.0
CH2_k127_340967_1 ATP-grasp domain K06913 - - 0.00000000000000000000000000000000000005902 150.0
CH2_k127_340967_2 Prokaryotic glutathione synthetase, ATP-grasp domain - - - 0.00000000000000000000000000000005222 133.0
CH2_k127_3414194_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 434.0
CH2_k127_3414194_1 Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000000000000002549 186.0
CH2_k127_3414194_2 TIGRFAM TonB family protein K03646 - - 0.00000000000000000000000000000000000000000000002566 186.0
CH2_k127_3452836_0 extracellular solute-binding protein - - - 3.661e-261 812.0
CH2_k127_3452836_1 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000006072 161.0
CH2_k127_3460051_0 catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 1.127e-220 693.0
CH2_k127_3460051_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 527.0
CH2_k127_3460051_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 451.0
CH2_k127_3460051_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 395.0
CH2_k127_3460051_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 406.0
CH2_k127_3460051_5 KR domain K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 373.0
CH2_k127_3460051_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000000156 138.0
CH2_k127_3460051_7 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000002024 100.0
CH2_k127_3460051_8 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000001912 97.0
CH2_k127_3465086_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 443.0
CH2_k127_3465086_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 312.0
CH2_k127_3465086_2 6-phosphogluconate dehydrogenase, C-terminal domain - - - 0.000000000000000000002471 109.0
CH2_k127_3465086_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000002159 89.0
CH2_k127_3483805_0 Sigma-54 interaction domain K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 602.0
CH2_k127_3483805_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000553 286.0
CH2_k127_3483805_2 - - - - 0.0009007 49.0
CH2_k127_3489490_0 - - - - 0.000000000000000000000000004236 116.0
CH2_k127_3489490_2 PFAM Integrase catalytic region - - - 0.000000000000000000004411 101.0
CH2_k127_3515728_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 520.0
CH2_k127_3515728_1 Histidine kinase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 421.0
CH2_k127_3515728_2 DNA polymerase X family K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 354.0
CH2_k127_3515728_3 response regulator K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009938 259.0
CH2_k127_3515728_4 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000000002812 141.0
CH2_k127_3522453_0 Bacterial capsule synthesis protein PGA_cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 303.0
CH2_k127_3522453_1 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002588 285.0
CH2_k127_3545810_0 Transglycosylase SLT domain K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 346.0
CH2_k127_3545810_1 NlpC/P60 family - - - 0.00000000000000000000000000000000000000000000000006319 184.0
CH2_k127_3545810_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000007536 176.0
CH2_k127_3545810_3 Belongs to the UPF0145 family - - - 0.00000000000000000000000006582 108.0
CH2_k127_360943_0 amino acid ABC transporter K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 446.0
CH2_k127_360943_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000002992 222.0
CH2_k127_3637204_0 response regulator receiver K07660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009177 327.0
CH2_k127_3637204_1 Histidine kinase K07637 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000008027 199.0
CH2_k127_3637204_2 - - - - 0.000000001519 62.0
CH2_k127_3637204_3 Glycine zipper 2TM domain - - - 0.00001434 48.0
CH2_k127_3732563_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 3.557e-267 829.0
CH2_k127_3732563_1 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 457.0
CH2_k127_3732563_2 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000008235 184.0
CH2_k127_3758884_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 331.0
CH2_k127_3758884_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 309.0
CH2_k127_3758884_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 305.0
CH2_k127_3758884_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000005396 234.0
CH2_k127_3758884_4 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000002581 192.0
CH2_k127_3760565_0 acyl-CoA dehydrogenase K06445 - - 0.0 1060.0
CH2_k127_3760565_1 Acyl-CoA dehydrogenase N terminal K20035 - - 1.38e-241 758.0
CH2_k127_3760565_2 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 370.0
CH2_k127_3760565_3 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000002922 246.0
CH2_k127_3760565_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000002019 213.0
CH2_k127_3760565_5 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000000006307 186.0
CH2_k127_3760615_0 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 7.374e-197 621.0
CH2_k127_3760615_1 pyridoxamine 5-phosphate K07006 - - 0.000000000000000000000000000000000000000000000000000000000000013 219.0
CH2_k127_3763295_0 Outer membrane protein beta-barrel family - - - 3.872e-246 771.0
CH2_k127_3763295_1 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 432.0
CH2_k127_3763295_2 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000005312 137.0
CH2_k127_3765904_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00244 - 1.3.5.4 8.227e-299 926.0
CH2_k127_3765904_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.588e-258 803.0
CH2_k127_3765904_2 PFAM fumarate reductase respiratory complex, transmembrane subunit K00246 - - 0.00000000000000000000000000000000000000000000000000002684 196.0
CH2_k127_3770777_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 458.0
CH2_k127_3770777_1 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 307.0
CH2_k127_3770777_2 branched-chain amino acid K01995 - - 0.000000000000000000000000000000000000000000000000000000000202 204.0
CH2_k127_3771656_0 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 505.0
CH2_k127_3771656_1 Molybdopterin oxidoreductase K00201 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 425.0
CH2_k127_3771656_2 PFAM molydopterin dinucleotide-binding region K00203 - 1.2.7.12 0.000000000000007875 79.0
CH2_k127_3779927_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.683e-197 620.0
CH2_k127_3779927_1 nitrite transmembrane transporter activity K08218,K08223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 546.0
CH2_k127_3779927_2 PFAM Methionine biosynthesis MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 299.0
CH2_k127_3779927_3 - - - - 0.00000000000000001906 95.0
CH2_k127_3786859_0 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 305.0
CH2_k127_3786859_1 Cytochrome P460 - - - 0.0000000000000000000000000000000000000000000000000000000000000000006609 243.0
CH2_k127_3786859_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000001436 160.0
CH2_k127_3792239_0 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 417.0
CH2_k127_3792239_1 SCO1/SenC - - - 0.0000000000000000000000000000000000000000000000000000000000000000002325 236.0
CH2_k127_3792239_2 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000623 240.0
CH2_k127_3792239_3 Transposase IS200 like - - - 0.0000000000004818 70.0
CH2_k127_3793853_0 AAA domain K02450,K12283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 409.0
CH2_k127_3793853_1 - - - - 0.000000000000000000000000000008777 125.0
CH2_k127_3805939_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 5.074e-243 764.0
CH2_k127_3805939_1 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 362.0
CH2_k127_3811963_0 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 290.0
CH2_k127_3811963_1 Belongs to the DnaA family K10763 - - 0.00000000000000000000000000000000000000000000000000000000000000000002186 241.0
CH2_k127_3811963_2 TIGRFAM HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.000000000000000000006691 92.0
CH2_k127_3820274_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 397.0
CH2_k127_3820274_1 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001188 270.0
CH2_k127_3820274_2 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000000000000000000000000000000000000000895 209.0
CH2_k127_3820274_3 oligosaccharyl transferase activity - - - 0.0000000000000000184 98.0
CH2_k127_3820274_4 methyltransferase - - - 0.000000001543 67.0
CH2_k127_3820274_5 Tetratricopeptide repeat - - - 0.000001915 62.0
CH2_k127_3821629_0 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000002133 119.0
CH2_k127_3821629_1 Thioredoxin-like - - - 0.0000000000000000000000000009162 126.0
CH2_k127_3821629_2 Tetratricopeptide repeat K02200 - - 0.00000000002275 64.0
CH2_k127_3821629_3 cytochrome c-type biogenesis protein CcsB - - - 0.00000000005939 74.0
CH2_k127_3825076_0 TIGRFAM Succinate dehydrogenase fumarate reductase iron-sulphur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 380.0
CH2_k127_3825076_1 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004386 272.0
CH2_k127_3825076_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00244 - 1.3.5.4 0.000000000000000000000004361 103.0
CH2_k127_3825076_3 - - - - 0.0000000000002421 76.0
CH2_k127_3827425_0 polyphosphate kinase - - - 5.529e-223 701.0
CH2_k127_3827425_1 CHAD - - - 0.00000000000000000000000000000000000000000000000000000000009215 213.0
CH2_k127_3827425_2 phosphohistidine phosphatase, SixA K08296 - - 0.00000000000000000000000000000000000000000000000182 178.0
CH2_k127_3909802_0 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 373.0
CH2_k127_3909802_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000003632 185.0
CH2_k127_3909802_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000002195 149.0
CH2_k127_3909802_3 HupE / UreJ protein - - - 0.000000000000000000000000000000000004843 145.0
CH2_k127_3909802_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000002574 134.0
CH2_k127_3927234_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 469.0
CH2_k127_3927234_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000003214 194.0
CH2_k127_3939432_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.195e-257 805.0
CH2_k127_3941067_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 1633.0
CH2_k127_4020351_0 Helicase K03722 - 3.6.4.12 2.644e-270 846.0
CH2_k127_4020351_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 8.583e-203 637.0
CH2_k127_4020351_2 COGs COG0076 Glutamate decarboxylase and related PLP-dependent protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 534.0
CH2_k127_4020351_3 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000001423 198.0
CH2_k127_4020351_4 - - - - 0.0000000000000000000000000000000000002013 147.0
CH2_k127_4020351_5 Universal stress protein family - - - 0.000000000000000000000000000001622 128.0
CH2_k127_4108979_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.941e-246 767.0
CH2_k127_4108979_1 Domain of unknown function (DUF4124) - - - 0.0000000000000000002611 94.0
CH2_k127_4108979_2 Tfp pilus assembly protein K08086 - - 0.00000000001855 74.0
CH2_k127_4212761_0 RimK-like ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 372.0
CH2_k127_4212761_1 formaldehyde-activating enzyme K10713 - 4.2.1.147 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 293.0
CH2_k127_4212761_2 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 - 3.5.4.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000008385 262.0
CH2_k127_4212761_3 ATP:dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000004269 255.0
CH2_k127_4212761_4 Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.00000000000000000000000000000000000000000000000000000006493 202.0
CH2_k127_4230178_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 9.426e-251 790.0
CH2_k127_4230178_1 PFAM Plasmid maintenance system killer K07334 - - 0.000000000005107 66.0
CH2_k127_423900_0 FAD-dependent pyridine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 527.0
CH2_k127_423900_1 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000000007869 231.0
CH2_k127_423900_2 Mut7-C ubiquitin - - - 0.000000000000000000000003884 115.0
CH2_k127_423900_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000004286 78.0
CH2_k127_423900_4 - - - - 0.000888 49.0
CH2_k127_4252760_0 LemA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002282 283.0
CH2_k127_4252760_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001383 286.0
CH2_k127_4252760_2 Cytochrome b561 K12262 - - 0.000000000000000000000000000000000000000000000000000000000000000004451 231.0
CH2_k127_4252760_3 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.00000000000000000000000000000000000000000000000000000005069 201.0
CH2_k127_4252760_4 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000001165 134.0
CH2_k127_4252760_6 Glycine zipper 2TM domain - - - 0.00000003896 63.0
CH2_k127_4264061_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 7.573e-209 655.0
CH2_k127_4264061_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 477.0
CH2_k127_4264061_2 Helix-turn-helix type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000718 404.0
CH2_k127_4264061_3 Belongs to the UPF0145 family - - - 0.0000000000000000000001895 103.0
CH2_k127_4264061_4 receptor - - - 0.000001475 55.0
CH2_k127_4264061_5 - - - - 0.0004584 47.0
CH2_k127_4264205_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 366.0
CH2_k127_4264205_1 Flagellar regulatory protein FleQ - - - 0.000000000000000000000000000000000000006112 149.0
CH2_k127_4264205_2 FIST N domain - - - 0.000000000000001175 77.0
CH2_k127_4270415_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1047.0
CH2_k127_4270415_1 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 292.0
CH2_k127_4270415_2 Fructose-1-6-bisphosphatase, N-terminal domain K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000008068 182.0
CH2_k127_4270415_3 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000006371 97.0
CH2_k127_4272602_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 9.789e-245 773.0
CH2_k127_4272602_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 392.0
CH2_k127_4272602_2 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002145 248.0
CH2_k127_4272602_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000000000000003736 115.0
CH2_k127_4272602_4 - - - - 0.00000000000000244 81.0
CH2_k127_4272602_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000032 84.0
CH2_k127_4288502_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000304 258.0
CH2_k127_4288502_1 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000001893 184.0
CH2_k127_4288502_2 - - - - 0.0000000000000004531 87.0
CH2_k127_4288502_3 - - - - 0.00000000000006469 80.0
CH2_k127_4288502_4 - - - - 0.00000000001313 74.0
CH2_k127_429012_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 3.209e-264 824.0
CH2_k127_4291093_0 His Kinase A (phospho-acceptor) domain - - - 0.0 1223.0
CH2_k127_4291093_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1114.0
CH2_k127_4291093_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 471.0
CH2_k127_4291093_3 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 369.0
CH2_k127_4291093_4 - - - - 0.0000000000000006124 79.0
CH2_k127_4297873_0 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 550.0
CH2_k127_4297873_1 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000137 251.0
CH2_k127_4297873_2 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000001403 222.0
CH2_k127_4297873_3 Aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000000009864 124.0
CH2_k127_4297873_4 mRNA catabolic process - - - 0.000000000000000000000000000004871 124.0
CH2_k127_4332635_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 319.0
CH2_k127_4332635_1 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000009026 166.0
CH2_k127_4332635_2 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000001884 138.0
CH2_k127_4353680_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.692e-289 893.0
CH2_k127_4353680_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 303.0
CH2_k127_4396685_0 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 346.0
CH2_k127_4396685_1 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000001561 266.0
CH2_k127_4396685_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000003809 265.0
CH2_k127_4396685_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000009356 174.0
CH2_k127_4400985_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.695e-316 980.0
CH2_k127_4400985_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 296.0
CH2_k127_4400985_2 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000003945 235.0
CH2_k127_4400985_3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000006206 230.0
CH2_k127_4400985_4 - - - - 0.00000000000001639 78.0
CH2_k127_4416992_0 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008614 373.0
CH2_k127_4416992_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 302.0
CH2_k127_4416992_2 Histidine phosphatase superfamily (branch 1) K08296 - - 0.00000000000000000000001312 104.0
CH2_k127_4416992_3 PFAM chemotaxis K03406,K07216 - - 0.000000000000000001713 90.0
CH2_k127_4442720_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 1.195e-199 627.0
CH2_k127_4442720_1 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 431.0
CH2_k127_4481389_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 615.0
CH2_k127_4481389_1 sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000000000000000006175 209.0
CH2_k127_4481389_2 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000639 145.0
CH2_k127_4481389_3 PFAM Peptidase M48 - - - 0.00000000000000000000000000000000307 133.0
CH2_k127_45212_0 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 303.0
CH2_k127_45212_1 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000001844 89.0
CH2_k127_4582585_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 545.0
CH2_k127_4582585_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 443.0
CH2_k127_4582585_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006195 288.0
CH2_k127_4582585_3 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000004234 263.0
CH2_k127_4677071_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1439.0
CH2_k127_4677071_1 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 320.0
CH2_k127_4685702_0 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 470.0
CH2_k127_4685702_1 response regulator K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 334.0
CH2_k127_4685702_2 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 317.0
CH2_k127_4685702_3 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000000000000000000005041 162.0
CH2_k127_4692038_0 Cytochrome c bacterial - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009156 605.0
CH2_k127_4692038_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000159 275.0
CH2_k127_4692112_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 1.191e-212 670.0
CH2_k127_4692112_1 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 428.0
CH2_k127_4692112_2 Pirin C-terminal cupin domain K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 397.0
CH2_k127_4692112_3 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006302 274.0
CH2_k127_4692112_4 Cytochrome B561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000000000000009712 234.0
CH2_k127_4699110_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 334.0
CH2_k127_4699110_1 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000008945 232.0
CH2_k127_4699110_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000001126 205.0
CH2_k127_4699110_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000009653 156.0
CH2_k127_4699110_4 Rubredoxin - - - 0.00000000000000000000000000001263 118.0
CH2_k127_4700794_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 7.27e-269 831.0
CH2_k127_4700794_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 457.0
CH2_k127_4700794_2 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 423.0
CH2_k127_4700794_3 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000000004897 138.0
CH2_k127_4700794_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000000004651 125.0
CH2_k127_4700794_5 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000001526 95.0
CH2_k127_4701498_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 439.0
CH2_k127_4701498_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 305.0
CH2_k127_4701624_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 1.102e-265 831.0
CH2_k127_4701624_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 2.398e-230 723.0
CH2_k127_4701854_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 389.0
CH2_k127_4701854_1 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000002048 220.0
CH2_k127_4701854_2 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000000000000000003121 207.0
CH2_k127_4701854_3 signal sequence binding - - - 0.0000000000000000000000000233 116.0
CH2_k127_4707294_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1292.0
CH2_k127_4707294_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 584.0
CH2_k127_4707294_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 555.0
CH2_k127_4707294_3 Prephenate dehydratase K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 482.0
CH2_k127_4707294_4 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000003834 200.0
CH2_k127_4707294_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000008154 172.0
CH2_k127_470785_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 471.0
CH2_k127_470785_1 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 358.0
CH2_k127_4714526_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 308.0
CH2_k127_4714526_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 295.0
CH2_k127_4714526_2 integral membrane protein K02221 - - 0.0000000000000000000000000000000000000000000000000000001574 201.0
CH2_k127_4714526_3 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000000000001639 117.0
CH2_k127_4714526_4 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.000000000000000001486 85.0
CH2_k127_4721637_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000005438 244.0
CH2_k127_4721637_1 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000001065 259.0
CH2_k127_4721637_2 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000001971 142.0
CH2_k127_4732036_0 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 463.0
CH2_k127_4732036_1 Pfam Periplasmic binding protein K02016,K06858 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005402 279.0
CH2_k127_4732036_2 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.00000000000000000000000000000000000000000000000000002049 191.0
CH2_k127_4732036_3 Transcriptional regulator, Crp Fnr family - - - 0.00000000000000000000000005145 122.0
CH2_k127_4736425_0 HPP family K07168 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007271 273.0
CH2_k127_4736425_1 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000000000003583 156.0
CH2_k127_4736425_2 Periplasmic lysozyme inhibitor of I-type lysozyme - - - 0.00000000000000000000000001567 122.0
CH2_k127_4736425_3 Phosphate acyltransferases - - - 0.000000000000008515 75.0
CH2_k127_4747797_0 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 382.0
CH2_k127_4747797_1 Peptidase S24-like - - - 0.000000000000000000000000000000000001177 144.0
CH2_k127_4747797_2 - - - - 0.00000000000000215 83.0
CH2_k127_4771632_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 535.0
CH2_k127_4771632_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000000000000000000000000000000795 209.0
CH2_k127_4771632_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000006388 152.0
CH2_k127_4786374_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 6.032e-200 632.0
CH2_k127_4786374_1 Heavy metal-associated domain protein K07213 - - 0.00000003474 55.0
CH2_k127_479375_0 Protein of unknown function - - - 0.0 1133.0
CH2_k127_479375_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1064.0
CH2_k127_479375_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 7.491e-195 616.0
CH2_k127_479375_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 543.0
CH2_k127_479375_4 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01769 - 4.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 465.0
CH2_k127_479375_5 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 424.0
CH2_k127_479375_6 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 416.0
CH2_k127_479375_7 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000008242 199.0
CH2_k127_479375_8 SnoaL-like domain - - - 0.0000000000000000000000000000000963 128.0
CH2_k127_479375_9 Zinc-finger domain - - - 0.0000000000000000000000000000002552 123.0
CH2_k127_480257_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.656e-263 821.0
CH2_k127_480257_1 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 375.0
CH2_k127_480257_2 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001434 259.0
CH2_k127_480257_3 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000002625 227.0
CH2_k127_480257_4 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000000000000000003446 219.0
CH2_k127_480257_5 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000004291 178.0
CH2_k127_4811528_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 568.0
CH2_k127_4811528_1 membrane - - - 0.0000000000000000000000000000000000000000001179 165.0
CH2_k127_4811528_2 Bacterial protein of unknown function (DUF883) - - - 0.00000000000000000000000000000005507 128.0
CH2_k127_4811528_3 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000008637 76.0
CH2_k127_4811528_4 RNA-metabolising metallo-beta-lactamase K07576 - - 0.0000000909 54.0
CH2_k127_4831734_0 - - - - 9.759e-267 839.0
CH2_k127_4831734_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 568.0
CH2_k127_4831734_2 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 558.0
CH2_k127_4831734_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000931 394.0
CH2_k127_4831734_4 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000003717 171.0
CH2_k127_4831734_5 - - - - 0.0000000000000000000000000000000000000000001481 167.0
CH2_k127_4831734_6 PFAM Cupin 2 conserved barrel domain protein K11312 - - 0.0000000000000000000000000000000000000000003651 166.0
CH2_k127_485996_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 1.076e-255 801.0
CH2_k127_485996_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000894 608.0
CH2_k127_485996_2 Long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 390.0
CH2_k127_485996_3 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007489 396.0
CH2_k127_485996_4 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005737 237.0
CH2_k127_485996_5 ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000003494 185.0
CH2_k127_485996_6 Acyl-ACP thioesterase - - - 0.000000000000000000000000000000000002364 141.0
CH2_k127_4864165_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1595.0
CH2_k127_4864165_1 Circularly permuted ATP-grasp type 2 - - - 7.347e-231 722.0
CH2_k127_4864165_2 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 385.0
CH2_k127_4864165_3 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 365.0
CH2_k127_4864165_4 PFAM 20S proteasome, A and B subunits K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 314.0
CH2_k127_4864165_5 glycosyl transferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 308.0
CH2_k127_4864165_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000002965 116.0
CH2_k127_4890999_0 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008697 537.0
CH2_k127_4890999_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 297.0
CH2_k127_4890999_2 Cytochrome C oxidase, cbb3-type, subunit III K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002768 266.0
CH2_k127_4890999_3 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000000000002417 193.0
CH2_k127_4920708_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 2.662e-287 883.0
CH2_k127_4920708_1 ribulose bisphosphate carboxylase small K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000003356 215.0
CH2_k127_493636_0 homolog of phage Mu protein gp47 - - - 2.443e-208 681.0
CH2_k127_493636_1 homolog of phage Mu protein gp47 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 457.0
CH2_k127_493636_2 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 399.0
CH2_k127_4964840_0 molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 314.0
CH2_k127_4964840_1 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000001894 172.0
CH2_k127_4964840_2 - - - - 0.0002427 46.0
CH2_k127_501974_0 alpha beta hydrolase fold K03821 - - 4.865e-245 771.0
CH2_k127_501974_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 544.0
CH2_k127_501974_2 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009078 544.0
CH2_k127_501974_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 322.0
CH2_k127_501974_4 Putative regulatory protein - - - 0.0000000000000000000000000000000002769 133.0
CH2_k127_5027803_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 504.0
CH2_k127_5027803_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 439.0
CH2_k127_5027803_2 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 430.0
CH2_k127_5027803_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 306.0
CH2_k127_5027803_4 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000002859 221.0
CH2_k127_5091770_0 Sigma-54 interaction domain - - - 2.814e-195 620.0
CH2_k127_5091770_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 604.0
CH2_k127_5091770_10 Protein of unknown function DUF72 - - - 0.00000000000000000001121 98.0
CH2_k127_5091770_11 response to antibiotic K07122 - - 0.000000000000000005796 89.0
CH2_k127_5091770_12 Glycosyl transferase family 41 - - - 0.0000000000007996 79.0
CH2_k127_5091770_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 431.0
CH2_k127_5091770_3 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 423.0
CH2_k127_5091770_4 ABC transport system ATP-binding protein K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 410.0
CH2_k127_5091770_5 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 369.0
CH2_k127_5091770_6 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 367.0
CH2_k127_5091770_7 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002992 258.0
CH2_k127_5091770_8 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000835 219.0
CH2_k127_5091770_9 Belongs to the BolA IbaG family - - - 0.000000000000000000000000003172 123.0
CH2_k127_5153825_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 440.0
CH2_k127_5153825_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000001276 231.0
CH2_k127_5153825_2 Protein of unknown function (DUF541) - - - 0.00000000000000000000000000000005027 135.0
CH2_k127_5153825_3 - - - - 0.00000000000000000000000000001591 122.0
CH2_k127_5158490_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 469.0
CH2_k127_5158490_1 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 319.0
CH2_k127_5158490_2 Aspartyl protease K06985 - - 0.000000000000000000000000000000000000003857 150.0
CH2_k127_5158490_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000003099 79.0
CH2_k127_5164203_0 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 358.0
CH2_k127_5164203_1 HD domain K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000001014 246.0
CH2_k127_5164203_10 Copper binding periplasmic protein CusF K07798,K15727 - - 0.00000000000000004966 90.0
CH2_k127_5164203_11 ATP-independent chaperone mediated protein folding - - - 0.00000000000004335 82.0
CH2_k127_5164203_12 - - - - 0.0004414 48.0
CH2_k127_5164203_2 Putative heavy-metal chelation - - - 0.00000000000000000000000000000000000000000000000000000000000000002347 241.0
CH2_k127_5164203_3 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000003549 202.0
CH2_k127_5164203_4 - - - - 0.00000000000000000000000000000000000000000000000000001554 197.0
CH2_k127_5164203_5 Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000003472 178.0
CH2_k127_5164203_6 Protein of unknown function, DUF - - - 0.00000000000000000000000000000000000000000000000817 175.0
CH2_k127_5164203_7 HlyD family secretion protein K07798,K15727 - - 0.00000000000000000000000000000002896 134.0
CH2_k127_5164203_8 - - - - 0.000000000000000000000001746 119.0
CH2_k127_5164203_9 - - - - 0.000000000000000002712 92.0
CH2_k127_5168375_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 536.0
CH2_k127_5168375_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 372.0
CH2_k127_5168375_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000001155 211.0
CH2_k127_517122_0 NiFe/NiFeSe hydrogenase small subunit C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 516.0
CH2_k127_517122_1 glycolate oxidase subunit GlcD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 339.0
CH2_k127_517122_2 nitrate reductase activity - - - 0.0000000000000000000009083 101.0
CH2_k127_5174122_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.78e-263 823.0
CH2_k127_5174122_1 Ammonium Transporter Family K03320,K06580 - - 2.215e-222 694.0
CH2_k127_5174122_2 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005731 248.0
CH2_k127_5176670_0 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 285.0
CH2_k127_5176670_1 WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000002266 246.0
CH2_k127_5176670_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000626 218.0
CH2_k127_5176670_3 Rubrerythrin - - - 0.000000000000000001561 85.0
CH2_k127_5177187_0 Domain of unknown function (DUF3391) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 332.0
CH2_k127_5177187_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 330.0
CH2_k127_5177187_2 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000003189 60.0
CH2_k127_518192_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2070.0
CH2_k127_5188500_0 ATP-dependent Clp protease ATP-binding subunit K03694 - - 0.0 1211.0
CH2_k127_5188500_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 336.0
CH2_k127_5188500_2 sulfide dehydrogenase K05301 - 1.8.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 321.0
CH2_k127_5188500_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000002316 220.0
CH2_k127_5188500_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000000001117 166.0
CH2_k127_5188500_5 cytochrome - - - 0.0000000000000000883 85.0
CH2_k127_5188500_6 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.0001147 45.0
CH2_k127_5189891_0 Threonine synthase K01733 - 4.2.3.1 4.097e-223 700.0
CH2_k127_5189891_1 homoserine dehydrogenase K00003 - 1.1.1.3 7.195e-200 626.0
CH2_k127_5218901_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 2.228e-236 733.0
CH2_k127_5218901_1 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000002376 66.0
CH2_k127_522262_0 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 317.0
CH2_k127_522262_1 Formaldehyde-activating enzyme (Fae) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 299.0
CH2_k127_522262_2 - - - - 0.00003331 46.0
CH2_k127_5233036_0 SecretomeP prediction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006997 343.0
CH2_k127_5233036_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 322.0
CH2_k127_5233036_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 283.0
CH2_k127_5233036_3 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000002038 208.0
CH2_k127_5250621_0 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 318.0
CH2_k127_5250621_1 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003043 245.0
CH2_k127_5250621_2 MobA-Related Protein K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000000000002142 205.0
CH2_k127_5250621_3 PFAM transcription elongation factor GreA GreB - - - 0.000000000000000000000000000000000000000000003396 173.0
CH2_k127_5250621_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000001177 128.0
CH2_k127_5260088_0 MMPL family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 348.0
CH2_k127_5260088_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 346.0
CH2_k127_5260088_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 327.0
CH2_k127_5279711_0 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 439.0
CH2_k127_5279711_1 Cytochrome C oxidase, cbb3-type, subunit III K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000001335 235.0
CH2_k127_5308829_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1483.0
CH2_k127_5308829_1 Sugar (and other) transporter - - - 1.362e-197 626.0
CH2_k127_5308829_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001055 271.0
CH2_k127_5308829_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000001287 220.0
CH2_k127_5308829_4 Histidine kinase - - - 0.000000000000000001188 88.0
CH2_k127_5334585_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.932e-223 698.0
CH2_k127_5334585_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 566.0
CH2_k127_5334585_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000004892 215.0
CH2_k127_5334585_11 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 - - 0.0000000000000000000000000000000000000000000000000000000000007372 212.0
CH2_k127_5334585_12 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000002141 207.0
CH2_k127_5334585_13 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000001195 205.0
CH2_k127_5334585_14 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000006109 168.0
CH2_k127_5334585_15 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000002702 166.0
CH2_k127_5334585_16 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000139 145.0
CH2_k127_5334585_17 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000000004065 143.0
CH2_k127_5334585_18 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000716 134.0
CH2_k127_5334585_19 Ribosomal protein L30 K02907 - - 0.00000000000000005939 89.0
CH2_k127_5334585_2 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 404.0
CH2_k127_5334585_20 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000005566 67.0
CH2_k127_5334585_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 344.0
CH2_k127_5334585_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 308.0
CH2_k127_5334585_5 Heparinase II/III N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 311.0
CH2_k127_5334585_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000763 280.0
CH2_k127_5334585_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008467 258.0
CH2_k127_5334585_8 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000000002992 236.0
CH2_k127_5334585_9 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000000000000000001425 226.0
CH2_k127_533557_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 423.0
CH2_k127_533557_1 PFAM YbaK prolyl-tRNA K19055 - - 0.000000000000005526 79.0
CH2_k127_533557_2 Carboxymuconolactone decarboxylase family - - - 0.0001011 44.0
CH2_k127_5344672_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 3.7e-297 924.0
CH2_k127_5344672_1 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 587.0
CH2_k127_5344672_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 518.0
CH2_k127_5344672_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 386.0
CH2_k127_5344672_4 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000101 219.0
CH2_k127_5344672_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000005018 165.0
CH2_k127_536204_0 TIGRFAM Formylmethanofuran dehydrogenase, subunit A K00200 - 1.2.7.12 1.324e-277 869.0
CH2_k127_536204_1 TIGRFAM formylmethanofuran dehydrogenase subunit B K00201 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 449.0
CH2_k127_536204_2 formylmethanofuran dehydrogenase activity K00202 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006201 275.0
CH2_k127_536204_3 beta-ribofuranosylaminobenzene 5'-phosphate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000006151 229.0
CH2_k127_54008_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 4.706e-305 943.0
CH2_k127_54008_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 608.0
CH2_k127_54008_2 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 536.0
CH2_k127_54008_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 380.0
CH2_k127_54008_4 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 326.0
CH2_k127_54008_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 307.0
CH2_k127_54008_6 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000002852 267.0
CH2_k127_54008_7 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000002696 165.0
CH2_k127_54008_8 Bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000009958 138.0
CH2_k127_54008_9 Lipopolysaccharide assembly protein A domain K08992 - - 0.00000000000000000007532 93.0
CH2_k127_5506190_0 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 338.0
CH2_k127_5506190_1 crp fnr family - - - 0.00000000000000000000000000000000000000000000000000000002183 197.0
CH2_k127_5547068_0 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 308.0
CH2_k127_5547068_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001503 230.0
CH2_k127_5547068_2 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000001227 182.0
CH2_k127_559011_0 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 342.0
CH2_k127_559011_1 Iron-sulfur cluster-binding domain K06139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 332.0
CH2_k127_5612933_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 443.0
CH2_k127_5612933_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 291.0
CH2_k127_5612933_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000001803 183.0
CH2_k127_5615263_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 562.0
CH2_k127_5615263_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 462.0
CH2_k127_5615263_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000001099 233.0
CH2_k127_5615263_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000003099 223.0
CH2_k127_5615263_4 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000003936 200.0
CH2_k127_5615263_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000005321 200.0
CH2_k127_5615263_6 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000001935 179.0
CH2_k127_5615263_7 PFAM peptidase - - - 0.0000000000000000000000000000000004585 133.0
CH2_k127_564803_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 3.856e-235 736.0
CH2_k127_564803_1 MltA specific insert domain K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 443.0
CH2_k127_564803_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 400.0
CH2_k127_564803_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 331.0
CH2_k127_564803_4 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009177 327.0
CH2_k127_564803_5 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000002525 263.0
CH2_k127_564803_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000004944 248.0
CH2_k127_564803_7 PFAM ApaG domain protein K06195 - - 0.0000000000000000000000000000000000000000000000000000001414 201.0
CH2_k127_565057_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 376.0
CH2_k127_565057_1 transcriptional - - - 0.00000000000000000000005004 100.0
CH2_k127_565057_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000001075 57.0
CH2_k127_5683069_0 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 555.0
CH2_k127_5683069_1 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.000000000000000000000000000005384 120.0
CH2_k127_5744005_0 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 401.0
CH2_k127_5744005_1 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 361.0
CH2_k127_5744005_2 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000006478 239.0
CH2_k127_5744005_3 protoporphyrinogen oxidase activity K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000008288 243.0
CH2_k127_5744005_4 Exopolysaccharide synthesis, ExoD - - - 0.0000000000000000000000000000000000000000000000000001406 192.0
CH2_k127_5744005_5 - - - - 0.000000000000000000000009605 105.0
CH2_k127_5823821_0 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001368 254.0
CH2_k127_5823821_1 Uncharacterised protein family (UPF0149) K07039 - - 0.0000000000000000000000000000000000000000000000002252 185.0
CH2_k127_5823821_2 Methyltransferase - - - 0.0000000000000000000000002396 115.0
CH2_k127_5823821_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000001382 55.0
CH2_k127_584880_0 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 3.682e-250 786.0
CH2_k127_584880_1 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000005735 55.0
CH2_k127_5977456_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 554.0
CH2_k127_5977456_1 DsrC like protein K11179 - - 0.00000000000000000000001882 113.0
CH2_k127_5977456_2 Alpha/beta hydrolase family - - - 0.000007389 48.0
CH2_k127_6028789_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 481.0
CH2_k127_6028789_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 439.0
CH2_k127_6028789_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000001598 52.0
CH2_k127_6054384_0 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 478.0
CH2_k127_6054384_1 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000002731 168.0
CH2_k127_6085895_0 Binding-protein-dependent transport system inner membrane component K02011 - - 8.159e-227 714.0
CH2_k127_6085895_1 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 501.0
CH2_k127_6085895_2 Uncharacterized protein conserved in bacteria (DUF2325) - - - 0.0000000000000000000000000000006647 125.0
CH2_k127_6085895_3 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000003954 53.0
CH2_k127_6085895_4 Alpha beta hydrolase - - - 0.0006046 44.0
CH2_k127_609855_0 amp-dependent synthetase and ligase - - - 5.861e-274 858.0
CH2_k127_609855_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 465.0
CH2_k127_6102325_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 3.697e-313 971.0
CH2_k127_6102325_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 539.0
CH2_k127_6102325_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 366.0
CH2_k127_6102325_3 photosynthesis - - - 0.000000000000000000000000000000000000000000004412 188.0
CH2_k127_6102325_4 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000000000000000009745 137.0
CH2_k127_6102325_5 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000005911 105.0
CH2_k127_610307_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 361.0
CH2_k127_610307_1 NMT1-like family K07080 - - 0.0000000000000000000009582 95.0
CH2_k127_6107389_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 493.0
CH2_k127_6107389_1 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 415.0
CH2_k127_6118170_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 548.0
CH2_k127_6118170_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 313.0
CH2_k127_6156263_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 396.0
CH2_k127_6156263_1 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 383.0
CH2_k127_6156263_2 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000009031 184.0
CH2_k127_6156263_3 MerR, DNA binding - - - 0.000000000000000000000000000000000000002665 151.0
CH2_k127_6162066_0 Soluble lytic murein transglycosylase L domain K08309 - - 2.68e-224 717.0
CH2_k127_6162066_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 606.0
CH2_k127_6162066_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 371.0
CH2_k127_6162066_3 - - - - 0.0000000000000000002056 93.0
CH2_k127_6162066_4 - - - - 0.0000000000000000008476 87.0
CH2_k127_6170816_0 (GGDEF) domain K21024 - 3.1.4.52 6.117e-194 646.0
CH2_k127_6170816_1 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000002143 222.0
CH2_k127_6187840_0 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 303.0
CH2_k127_6187840_1 periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000001165 200.0
CH2_k127_6187840_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000007917 186.0
CH2_k127_6187840_3 LppC putative lipoprotein K07121 - - 0.00000000000000000000000000000000000000000001188 168.0
CH2_k127_6187840_4 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000548 151.0
CH2_k127_6187840_5 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000001289 147.0
CH2_k127_6198303_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 2.014e-197 621.0
CH2_k127_6198303_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 332.0
CH2_k127_6218424_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 452.0
CH2_k127_6218424_1 Histidine kinase K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 366.0
CH2_k127_6218424_2 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000002367 232.0
CH2_k127_6218424_3 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001576 232.0
CH2_k127_6218424_4 Protein of unknown function (DUF3301) - - - 0.000000000000000000001549 101.0
CH2_k127_6228860_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 547.0
CH2_k127_6229230_0 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 525.0
CH2_k127_6229230_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 440.0
CH2_k127_6229230_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000004078 135.0
CH2_k127_6238173_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 389.0
CH2_k127_6238173_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000007434 207.0
CH2_k127_6238173_2 Bacterial transcriptional repressor C-terminal K09017 - - 0.0000000000000005648 79.0
CH2_k127_6255672_0 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 295.0
CH2_k127_6255672_1 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001177 266.0
CH2_k127_6268182_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 4.362e-233 729.0
CH2_k127_6268182_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 406.0
CH2_k127_6268182_2 VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001156 260.0
CH2_k127_6271358_0 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 545.0
CH2_k127_6271358_1 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 462.0
CH2_k127_6271358_2 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 354.0
CH2_k127_6271358_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000334 252.0
CH2_k127_6271358_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000004118 214.0
CH2_k127_6271358_5 Phosphate transporter K03306 - - 0.00000000000000000000008205 98.0
CH2_k127_6286553_0 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 318.0
CH2_k127_6286553_1 Heavy metal transport detoxification protein K17686,K19597 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004107 308.0
CH2_k127_6286553_2 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000002222 244.0
CH2_k127_6291029_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 555.0
CH2_k127_629585_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 480.0
CH2_k127_629585_1 Belongs to the HypD family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 312.0
CH2_k127_629585_2 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000007448 117.0
CH2_k127_6311416_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 1497.0
CH2_k127_6311416_1 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 417.0
CH2_k127_6311416_2 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008287 270.0
CH2_k127_6360978_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 4.127e-195 619.0
CH2_k127_6360978_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000006766 179.0
CH2_k127_6360978_2 Putative molybdenum carrier - - - 0.000000000000000000000000000000000000000000003066 177.0
CH2_k127_6360978_3 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000002616 163.0
CH2_k127_6360978_4 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000002571 117.0
CH2_k127_6362741_0 L,D-transpeptidase catalytic domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 457.0
CH2_k127_6362741_1 1-deoxy-D-xylulose-5-phosphate synthase K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 408.0
CH2_k127_6362741_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 329.0
CH2_k127_6362741_3 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000005616 173.0
CH2_k127_6362741_4 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000006233 117.0
CH2_k127_6362741_5 Transcriptional regulator - - - 0.00000004526 54.0
CH2_k127_6367844_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 571.0
CH2_k127_6367844_1 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 574.0
CH2_k127_6367844_2 PFAM type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 463.0
CH2_k127_6367844_3 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 443.0
CH2_k127_6367844_4 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 425.0
CH2_k127_6367844_5 S4 RNA-binding domain K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 304.0
CH2_k127_6367844_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 289.0
CH2_k127_637367_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 512.0
CH2_k127_637367_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 346.0
CH2_k127_6540837_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 3.806e-246 775.0
CH2_k127_6540837_1 protein conserved in bacteria K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 465.0
CH2_k127_6540837_2 VWA-like domain (DUF2201) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 455.0
CH2_k127_6540837_3 Sugar fermentation stimulation protein K06206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 309.0
CH2_k127_6540837_4 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000000000000000000000000000000000009251 223.0
CH2_k127_6540837_5 associated with various cellular activities - - - 0.000000000000000000000000000000000008638 138.0
CH2_k127_655689_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 484.0
CH2_k127_655689_1 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 286.0
CH2_k127_6575565_0 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004512 256.0
CH2_k127_6575565_1 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000000000000000001823 124.0
CH2_k127_6575565_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000001097 59.0
CH2_k127_6585346_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 460.0
CH2_k127_6585346_1 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 411.0
CH2_k127_6585346_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 369.0
CH2_k127_6585346_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 304.0
CH2_k127_6585346_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000001461 226.0
CH2_k127_6585346_5 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000001926 204.0
CH2_k127_6585346_6 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000000001641 188.0
CH2_k127_6585346_7 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000007873 173.0
CH2_k127_6585346_8 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000005571 124.0
CH2_k127_6603375_0 MMPL family - - - 5.395e-294 917.0
CH2_k127_6603375_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000126 230.0
CH2_k127_6603375_2 Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000203 128.0
CH2_k127_6603375_3 - - - - 0.0000000000000000000000000000009402 128.0
CH2_k127_6603375_4 - - - - 0.0000000000000000000001871 106.0
CH2_k127_6607769_0 formate dehydrogenase K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 345.0
CH2_k127_6607769_1 - - - - 0.0000000000000001156 85.0
CH2_k127_6607769_2 - - - - 0.00000000000001114 75.0
CH2_k127_6636634_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001501 276.0
CH2_k127_6636634_1 HIT domain - - - 0.000006437 49.0
CH2_k127_6637499_0 Histidine kinase - - - 7.44e-221 712.0
CH2_k127_6637499_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 490.0
CH2_k127_6637499_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 366.0
CH2_k127_6637499_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000005198 238.0
CH2_k127_6637499_4 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000000000000000000004737 175.0
CH2_k127_664764_0 Homoserine dehydrogenase, NAD binding domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 519.0
CH2_k127_664764_1 Cytochrome P460 - - - 0.0000007142 59.0
CH2_k127_665491_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 494.0
CH2_k127_665491_1 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 311.0
CH2_k127_665491_2 - - - - 0.000000000000000000000000000000000000000000000000000002353 196.0
CH2_k127_665491_3 Phasin protein - - - 0.00000000000000000000000000000000000001062 151.0
CH2_k127_665491_4 Inner membrane protein PRK11099 K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000009605 131.0
CH2_k127_665491_5 Dioxygenase - - - 0.0000000000000000000000000000731 122.0
CH2_k127_6655727_0 plastoquinol--plastocyanin reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004354 265.0
CH2_k127_6655727_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000004285 202.0
CH2_k127_6655727_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.00000000000000000000000000001505 120.0
CH2_k127_6657522_0 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 319.0
CH2_k127_6657522_1 Esterase, phb depolymerase family - - - 0.000000000000000000000000000000000000000000000000000000000000001087 233.0
CH2_k127_6663713_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 4.856e-242 766.0
CH2_k127_6663713_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000005178 213.0
CH2_k127_6665094_0 Biotin carboxylase C-terminal domain K01965,K01968,K13777 - 6.4.1.3,6.4.1.4,6.4.1.5 2.336e-263 823.0
CH2_k127_6669429_0 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 395.0
CH2_k127_6669429_1 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 328.0
CH2_k127_6669429_2 - - - - 0.0000000000000000000000000000006373 132.0
CH2_k127_6669429_4 Pregnancy-associated plasma protein-A - - - 0.000000000000000003633 89.0
CH2_k127_6673204_0 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 438.0
CH2_k127_6673204_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 291.0
CH2_k127_6673204_2 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000004384 217.0
CH2_k127_6673204_3 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000002394 212.0
CH2_k127_6683727_0 Heavy-metal-associated domain K01533 - 3.6.3.4 1.859e-292 920.0
CH2_k127_6683727_1 Belongs to the heme-copper respiratory oxidase family K00404 GO:0003674,GO:0003824,GO:0004129,GO:0005215,GO:0005488,GO:0005506,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008144,GO:0008150,GO:0008152,GO:0008324,GO:0009055,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015002,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0015975,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0016310,GO:0016491,GO:0016675,GO:0016676,GO:0016705,GO:0017144,GO:0019411,GO:0019637,GO:0019646,GO:0019693,GO:0019825,GO:0020037,GO:0022857,GO:0022890,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045154,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0055114,GO:0070069,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901135,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000006191 261.0
CH2_k127_6683727_2 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005002 263.0
CH2_k127_6683727_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000007804 210.0
CH2_k127_6683727_4 cytochrome oxidase maturation protein cbb3-type - - - 0.0000000000000003117 81.0
CH2_k127_6684528_0 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 565.0
CH2_k127_6684528_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 513.0
CH2_k127_6684528_2 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 513.0
CH2_k127_6684528_3 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003856 258.0
CH2_k127_6684528_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000009241 231.0
CH2_k127_6684528_5 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000521 213.0
CH2_k127_6684528_6 YCII-related domain - - - 0.000000000000000000000000000000000000000000207 164.0
CH2_k127_6688020_0 Formylmethanofuran-tetrahydromethanopterin formyltransferase K00672 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0071704 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007901 456.0
CH2_k127_6688020_1 TIGRFAM formylmethanofuran dehydrogenase subunit C K00202 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000005217 257.0
CH2_k127_6688020_2 - - - - 0.000000000000000000000000000000000000000000000000006239 189.0
CH2_k127_6694626_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 1.967e-286 891.0
CH2_k127_6694626_1 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004685 282.0
CH2_k127_6694626_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000003243 209.0
CH2_k127_6694626_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000002434 131.0
CH2_k127_6695020_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 576.0
CH2_k127_6695020_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 301.0
CH2_k127_6695020_2 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000001901 211.0
CH2_k127_6695020_3 - - - - 0.0000000000000000000000001595 112.0
CH2_k127_6695020_4 Phospholipase_D-nuclease N-terminal - - - 0.000000000000000004623 86.0
CH2_k127_6695020_5 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.00000000000000001987 81.0
CH2_k127_6698329_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 532.0
CH2_k127_6698329_1 PFAM MgtC SapB transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 508.0
CH2_k127_6701352_0 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 391.0
CH2_k127_6701352_1 Molybdenum ABC transporter K02020 - - 0.00000000000000000000000000000000000000000000000003322 183.0
CH2_k127_6715216_0 Sulfate permease family K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000009381 247.0
CH2_k127_6715216_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000004303 205.0
CH2_k127_6715216_2 Histidine kinase K07637 - 2.7.13.3 0.0000000000000000000000000000000000000178 146.0
CH2_k127_6721643_0 Animal haem peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 503.0
CH2_k127_6732874_0 PFAM Glycoside hydrolase 15-related - - - 7.602e-287 902.0
CH2_k127_6732874_1 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000004081 221.0
CH2_k127_6732874_2 Universal stress protein family - - - 0.0000000000000000000000000000003314 126.0
CH2_k127_6734949_0 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 610.0
CH2_k127_6734949_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 370.0
CH2_k127_6734949_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 354.0
CH2_k127_6734949_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 321.0
CH2_k127_6778135_0 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000003177 194.0
CH2_k127_6778135_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.000000000000000000000000000000000000000003515 166.0
CH2_k127_6778135_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.0000000000000000000000000000000001014 150.0
CH2_k127_6778135_3 PFAM Fibronectin, type III domain - - - 0.000000006175 67.0
CH2_k127_6791314_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 527.0
CH2_k127_6791314_1 Metal binding domain of Ada K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 507.0
CH2_k127_6791314_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 497.0
CH2_k127_6791314_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 407.0
CH2_k127_6791314_4 MotA TolQ ExbB proton channel K03561 - - 0.000000005419 57.0
CH2_k127_6803760_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000101 242.0
CH2_k127_6803760_1 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000004476 213.0
CH2_k127_6803760_2 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000002044 124.0
CH2_k127_6803760_3 Small multidrug resistance protein K11741 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046618,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000003777 118.0
CH2_k127_6813782_0 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 357.0
CH2_k127_6813782_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 331.0
CH2_k127_6813782_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000002693 204.0
CH2_k127_6813782_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000001726 117.0
CH2_k127_683197_0 protein synthesis factor, GTP-binding K06207 - - 1.689e-315 974.0
CH2_k127_683197_1 His Kinase A (phosphoacceptor) domain - - - 8.116e-293 932.0
CH2_k127_683197_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 343.0
CH2_k127_683197_3 response regulator receiver K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 296.0
CH2_k127_683197_4 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000001253 221.0
CH2_k127_683197_5 Single Cache domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000886 207.0
CH2_k127_683197_6 periplasmic protein - - - 0.0000000000000001663 92.0
CH2_k127_6966948_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 374.0
CH2_k127_6966948_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009238 331.0
CH2_k127_6966948_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 329.0
CH2_k127_6986238_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 475.0
CH2_k127_6986238_1 Transcriptional regulator K15539 - - 0.000000000000000000000000000000000000000001935 165.0
CH2_k127_7043094_0 protein conserved in bacteria K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008892 281.0
CH2_k127_7043094_1 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000005239 184.0
CH2_k127_7047891_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 531.0
CH2_k127_7047891_1 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 328.0
CH2_k127_7047891_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001104 254.0
CH2_k127_7047891_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000001119 179.0
CH2_k127_706235_0 - - - - 0.000000000000000000000000000000002875 138.0
CH2_k127_706235_1 Amidohydrolase K01686 - 4.2.1.8 0.00000000000000000000000006428 108.0
CH2_k127_706235_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000001082 117.0
CH2_k127_7077765_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 4.737e-314 979.0
CH2_k127_7077765_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 564.0
CH2_k127_7077765_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000000000008925 188.0
CH2_k127_7082861_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007278 547.0
CH2_k127_7082861_1 COG0569 K transport systems, NAD-binding component K03499 - - 0.000000000000000000002944 94.0
CH2_k127_7084552_0 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 351.0
CH2_k127_7084552_1 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 290.0
CH2_k127_7084552_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 0.00000000000000000000000000000000000000000000000001608 184.0
CH2_k127_7113799_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 475.0
CH2_k127_7113799_1 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003374 287.0
CH2_k127_7113799_2 - - - - 0.0000000000000000000000000000000000000000000000004749 188.0
CH2_k127_7113799_3 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000001208 171.0
CH2_k127_7113799_4 PFAM Phosphoglycerate mutase K22305 - 3.1.3.3 0.00000000000000000000000999 117.0
CH2_k127_7113799_5 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000009606 70.0
CH2_k127_7116073_0 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 2.806e-211 665.0
CH2_k127_7116073_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000003027 103.0
CH2_k127_7116073_2 protein related to plant photosystem II stability assembly factor - - - 0.00000000000003508 81.0
CH2_k127_7118573_0 COG0491 Zn-dependent hydrolases, including glyoxylases K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 346.0
CH2_k127_7118573_1 histidine kinase HAMP region domain protein K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 329.0
CH2_k127_7118573_2 helix_turn_helix, Lux Regulon K07689 - - 0.0000000000000000000000000000000000000000000000000000000000000000001125 250.0
CH2_k127_7121638_0 Histidine kinase K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 387.0
CH2_k127_7121638_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 357.0
CH2_k127_7121638_10 SpoIIAA-like - - - 0.0000000000000000000000000000001162 128.0
CH2_k127_7121638_11 Tetratricopeptide repeat - - - 0.000000000000000000000000002059 120.0
CH2_k127_7121638_12 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000007486 114.0
CH2_k127_7121638_13 EF-hand domain pair - - - 0.000000000000001507 87.0
CH2_k127_7121638_14 Appr-1'-p processing enzyme - - - 0.0000000000005034 71.0
CH2_k127_7121638_15 Protein of unknown function (DUF3106) - - - 0.0001077 51.0
CH2_k127_7121638_2 response regulator K02483,K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 330.0
CH2_k127_7121638_3 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 288.0
CH2_k127_7121638_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005373 273.0
CH2_k127_7121638_5 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004466 255.0
CH2_k127_7121638_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000001526 226.0
CH2_k127_7121638_7 Protein required for attachment to host cells - - - 0.000000000000000000000000000000000000000000000000000003378 193.0
CH2_k127_7121638_8 LigT like Phosphoesterase - - - 0.000000000000000000000000000000000000000007147 160.0
CH2_k127_7121638_9 Protein of unknown function (DUF3175) - - - 0.00000000000000000000000000000000005821 137.0
CH2_k127_7124178_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.987e-320 994.0
CH2_k127_7124178_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 573.0
CH2_k127_7124178_2 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001299 248.0
CH2_k127_7124178_3 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000001315 173.0
CH2_k127_7149833_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 1.417e-194 620.0
CH2_k127_7149833_1 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 290.0
CH2_k127_7149833_2 Phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000002008 263.0
CH2_k127_716687_0 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 604.0
CH2_k127_7182760_0 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 353.0
CH2_k127_7182760_1 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000008964 264.0
CH2_k127_7182760_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000001453 194.0
CH2_k127_7194278_0 Bacterial periplasmic substrate-binding proteins K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 441.0
CH2_k127_7194278_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 351.0
CH2_k127_7194278_2 Binding-protein-dependent transport system inner membrane component K02029,K10003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 317.0
CH2_k127_7194278_3 Binding-protein-dependent transport system inner membrane component K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 323.0
CH2_k127_7194278_4 ABC transporter K02028,K10004 - 3.6.3.21 0.0000000000000000000000002325 117.0
CH2_k127_7204257_0 CoA-binding domain protein K09181 - - 0.0 1077.0
CH2_k127_7204257_1 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 457.0
CH2_k127_7204257_2 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 426.0
CH2_k127_7204257_3 CHASE3 domain - - - 0.00000000000000000000000000000000000000000003948 182.0
CH2_k127_7204257_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000001552 100.0
CH2_k127_7236088_0 TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 579.0
CH2_k127_7236088_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000007802 252.0
CH2_k127_7236088_2 - - - - 0.0000000000000009311 87.0
CH2_k127_7236088_3 - - - - 0.00000005646 64.0
CH2_k127_7244561_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 1069.0
CH2_k127_7252431_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 5.018e-242 754.0
CH2_k127_7252431_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000009972 243.0
CH2_k127_7252431_2 glutamate synthase, alpha subunit domain protein K00265 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000001124 240.0
CH2_k127_727260_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 445.0
CH2_k127_727260_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 385.0
CH2_k127_727260_2 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000000000006638 225.0
CH2_k127_727260_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000001125 177.0
CH2_k127_7312588_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 358.0
CH2_k127_7312588_1 response regulator K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 313.0
CH2_k127_7312588_2 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000001692 109.0
CH2_k127_7364612_0 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000906 574.0
CH2_k127_7364612_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001301 291.0
CH2_k127_7364612_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000002811 136.0
CH2_k127_7364612_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000364 129.0
CH2_k127_7364612_4 Thioredoxin domain - - - 0.000000000000000000000000984 105.0
CH2_k127_7364612_5 4Fe-4S binding domain - - - 0.000000000000000000003226 107.0
CH2_k127_7364612_6 component of anaerobic dehydrogenases - - - 0.00000000000001429 85.0
CH2_k127_7382723_0 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 6.908e-214 666.0
CH2_k127_7382723_1 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 356.0
CH2_k127_7382723_2 sulfur relay protein TusD DsrE K07235 - - 0.00000000000000000000000000000000000000000000000000000001167 215.0
CH2_k127_7382723_3 Sulfur relay protein TusC DsrF K07236 - - 0.000000000000000000000000000000000000000001644 166.0
CH2_k127_738577_0 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 376.0
CH2_k127_738577_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 344.0
CH2_k127_738577_2 PFAM Bacterial protein of - - - 0.000000000000000000000000000000000000000000000000000000000000000000005044 240.0
CH2_k127_738577_3 Cyclophilin-like K09143 - - 0.00000000000000000000000000000003813 125.0
CH2_k127_738577_4 malic enzyme K00027,K00029 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40 0.000000000000006727 75.0
CH2_k127_738577_5 - - - - 0.00000005759 63.0
CH2_k127_7417233_0 cellulose binding - - - 1.226e-212 689.0
CH2_k127_7417233_1 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001814 251.0
CH2_k127_7437183_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 529.0
CH2_k127_7437183_1 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004828 271.0
CH2_k127_7437183_2 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000001297 233.0
CH2_k127_7437183_3 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000003853 201.0
CH2_k127_7437183_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000004064 136.0
CH2_k127_7457246_0 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 431.0
CH2_k127_7457246_1 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 339.0
CH2_k127_7457246_2 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006659 250.0
CH2_k127_7457246_3 Ferredoxin - - - 0.00000000000000000000000000000000000000000000001617 172.0
CH2_k127_747825_0 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 506.0
CH2_k127_747825_1 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 396.0
CH2_k127_747825_2 Protein of unknown function (DUF1499) - - - 0.00000000001744 64.0
CH2_k127_7492603_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 7.317e-309 952.0
CH2_k127_7492603_1 ribonuclease, Rne Rng family K08301 - - 3.123e-233 736.0
CH2_k127_7492603_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 2.075e-213 675.0
CH2_k127_7492603_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000003713 247.0
CH2_k127_7492603_4 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000002312 224.0
CH2_k127_7492603_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000297 197.0
CH2_k127_7492603_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000009055 137.0
CH2_k127_7499579_0 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 607.0
CH2_k127_7499579_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 344.0
CH2_k127_7499579_2 Outer membrane lipoprotein LolB - - - 0.0000000000000000000000000000000000000005414 157.0
CH2_k127_7499579_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000007994 72.0
CH2_k127_7504883_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 6.243e-291 906.0
CH2_k127_7504883_1 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 319.0
CH2_k127_7504883_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000002404 235.0
CH2_k127_7504883_3 AAA ATPase central domain protein K07478 - - 0.00000000000000302 76.0
CH2_k127_7520206_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006424 284.0
CH2_k127_7520206_1 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001288 258.0
CH2_k127_7520206_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000002385 167.0
CH2_k127_7520206_3 Domain of unknown function (DUF1840) - - - 0.000000000000000001054 95.0
CH2_k127_7520206_4 - - - - 0.0003703 43.0
CH2_k127_7527242_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 484.0
CH2_k127_7527242_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000004721 235.0
CH2_k127_7527242_2 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000002135 122.0
CH2_k127_7543680_0 Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 352.0
CH2_k127_7543680_1 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000000000000003825 205.0
CH2_k127_7543680_2 DsrH like protein K07237 - - 0.00000000000000000000000000000003532 128.0
CH2_k127_7543680_3 Sulfur relay protein TusC DsrF K07236 - - 0.0000000000000000000000000000004716 123.0
CH2_k127_7550699_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 578.0
CH2_k127_7550699_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007696 421.0
CH2_k127_7550699_10 NusG domain II - - - 0.000000000000000000000000000000000000000005605 157.0
CH2_k127_7550699_11 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.00000000000000000000000000000000000000005728 156.0
CH2_k127_7550699_12 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000000000000002191 140.0
CH2_k127_7550699_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 410.0
CH2_k127_7550699_3 P-loop ATPase protein family K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 386.0
CH2_k127_7550699_4 Branched-chain amino acid ATP-binding cassette transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 391.0
CH2_k127_7550699_5 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000008419 228.0
CH2_k127_7550699_6 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.000000000000000000000000000000000000000000000000000000000000012 221.0
CH2_k127_7550699_7 PFAM Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000000000000000000000000000000000000000003019 216.0
CH2_k127_7550699_8 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000009755 214.0
CH2_k127_7550699_9 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000000000000000005203 186.0
CH2_k127_7561119_0 D-amino acid dehydrogenase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 316.0
CH2_k127_7561119_1 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001204 260.0
CH2_k127_7566906_0 Heparinase II/III N-terminus - - - 0.00000000000000000000304 104.0
CH2_k127_7566906_1 homoserine kinase activity - - - 0.000009113 59.0
CH2_k127_7578579_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 554.0
CH2_k127_7578579_1 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 390.0
CH2_k127_7578579_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 289.0
CH2_k127_7578579_3 peptidase M24B X-Pro dipeptidase aminopeptidase domain protein K01262 - 3.4.11.9 0.000000000000000000000000001651 112.0
CH2_k127_7578579_4 Belongs to the transcriptional regulatory Fis family K03557 - - 0.0000000000000000000000001064 114.0
CH2_k127_7600075_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 5.767e-304 941.0
CH2_k127_7600075_1 exodeoxyribonuclease iii K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000001388 236.0
CH2_k127_7612352_0 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 513.0
CH2_k127_7612352_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000001322 179.0
CH2_k127_7612352_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000007574 184.0
CH2_k127_7648947_0 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 343.0
CH2_k127_7648947_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000285 175.0
CH2_k127_7648947_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000344 129.0
CH2_k127_7648947_3 - - - - 0.00000000000000000002043 94.0
CH2_k127_7681392_0 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0044281,GO:0071704 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 379.0
CH2_k127_7681392_1 formylmethanofuran dehydrogenase activity K00202 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.0000000000000000000000000000000001716 138.0
CH2_k127_7681392_2 Formylmethanofuran dehydrogenase subunit A K00200 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281 1.2.7.12 0.00000000001147 67.0
CH2_k127_7745077_0 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 601.0
CH2_k127_7745077_1 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000145 267.0
CH2_k127_7745077_2 PFAM AMMECR1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000571 238.0
CH2_k127_7745077_3 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.00000000000000000000000000000000000000003222 156.0
CH2_k127_7745077_4 regulation of microtubule-based process K06990 - - 0.00000000000000008761 80.0
CH2_k127_77524_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 522.0
CH2_k127_77524_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 524.0
CH2_k127_77524_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 355.0
CH2_k127_77524_3 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000301 185.0
CH2_k127_7784748_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1022.0
CH2_k127_7784748_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008382 351.0
CH2_k127_7867403_0 protein containing a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 387.0
CH2_k127_7867403_1 Peptidoglycan-binding domain 1 protein K02450,K03791,K17733 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 369.0
CH2_k127_7867403_2 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 364.0
CH2_k127_7867403_3 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000000000001266 170.0
CH2_k127_7867403_4 - - - - 0.0000000001692 66.0
CH2_k127_7867403_5 Phage tail sheath C-terminal domain K06907 - - 0.00000001488 56.0
CH2_k127_7904233_0 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 413.0
CH2_k127_7904233_1 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.000000000000000000000000000000001971 132.0
CH2_k127_7956018_0 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 486.0
CH2_k127_7956018_2 serine threonine protein kinase - - - 0.0000000000000000000003354 97.0
CH2_k127_7956018_4 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.00000000000005165 74.0
CH2_k127_7957436_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1471.0
CH2_k127_7957436_1 Outer membrane efflux protein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 501.0
CH2_k127_7957436_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 428.0
CH2_k127_7957436_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000002249 146.0
CH2_k127_7963945_0 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 500.0
CH2_k127_7963945_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 349.0
CH2_k127_7963945_2 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000009295 212.0
CH2_k127_7974742_0 HlyD family K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 304.0
CH2_k127_7974742_1 Bacterial transcriptional repressor C-terminal K09017 - - 0.000000000000000000000000000000000000000000000000000002035 197.0
CH2_k127_7979890_0 AsmA family K07289,K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000177 234.0
CH2_k127_7983895_0 chain 5 L K00341 - 1.6.5.3 3.135e-273 852.0
CH2_k127_7983895_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.666e-263 818.0
CH2_k127_7983895_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.738e-208 659.0
CH2_k127_7983895_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 363.0
CH2_k127_7983895_4 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000001354 229.0
CH2_k127_7983895_5 Enoyl-CoA hydratase/isomerase K01782,K01825,K07516,K13816 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.000000003913 58.0
CH2_k127_7986252_0 FeS assembly protein SufB K09014 - - 7.072e-278 859.0
CH2_k127_7986252_1 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 411.0
CH2_k127_7986252_2 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 389.0
CH2_k127_7986252_3 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000006164 167.0
CH2_k127_799912_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.818e-282 877.0
CH2_k127_799912_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 512.0
CH2_k127_799912_2 membrane - - - 0.00000000000000000000000008021 113.0
CH2_k127_8003301_0 modulator of DNA gyrase K03568 - - 7.301e-207 646.0
CH2_k127_8003301_1 DAHP synthetase I family K03856 - 2.5.1.54 0.0000000000000000000000003901 107.0
CH2_k127_8003301_2 Dodecin K09165 - - 0.0000000000000000000002067 100.0
CH2_k127_8008554_0 Histidine kinase - - - 7.617e-243 775.0
CH2_k127_8008554_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 492.0
CH2_k127_8008554_2 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 295.0
CH2_k127_8008554_3 Bacterial regulatory proteins, tetR family K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000074 284.0
CH2_k127_8008554_4 - - - - 0.00000000004577 76.0
CH2_k127_8020179_0 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 418.0
CH2_k127_8020179_1 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000001037 179.0
CH2_k127_8020179_2 AAA domain K06217 - - 0.000000000000000000000000000000000001484 138.0
CH2_k127_8020179_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000002977 107.0
CH2_k127_8022649_0 AMP-binding enzyme C-terminal domain K00666 - - 6.554e-283 880.0
CH2_k127_8022649_1 von Willebrand factor (vWF) type A domain - - - 5.149e-230 739.0
CH2_k127_8022649_10 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.000000000000000000000000000000000000000000000000008189 184.0
CH2_k127_8022649_11 TPM domain K06872 - - 0.0000000000000000000000000000003686 128.0
CH2_k127_8022649_12 - - - - 0.000000000000000000000000004353 114.0
CH2_k127_8022649_13 - - - - 0.00000000000000000002013 95.0
CH2_k127_8022649_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 4.75e-222 695.0
CH2_k127_8022649_3 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 562.0
CH2_k127_8022649_4 PFAM ATPase associated with various cellular activities K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 428.0
CH2_k127_8022649_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 421.0
CH2_k127_8022649_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 421.0
CH2_k127_8022649_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 415.0
CH2_k127_8022649_8 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 380.0
CH2_k127_8022649_9 TPM domain - - - 0.00000000000000000000000000000000000000000000000000000004802 203.0
CH2_k127_8037476_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 551.0
CH2_k127_8037476_1 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007837 322.0
CH2_k127_8037476_2 transcriptional - - - 0.000000000000000000000000121 109.0
CH2_k127_8040898_0 von Willebrand factor (vWF) type A domain - - - 1.624e-295 917.0
CH2_k127_8041060_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007328 288.0
CH2_k127_8041060_1 Predicted permease K07089 - - 0.000000000000000000000000000000000000001632 149.0
CH2_k127_8041060_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000003948 135.0
CH2_k127_8041060_3 Thioredoxin domain - - - 0.0000000000000000000000007167 105.0
CH2_k127_8041060_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000002633 104.0
CH2_k127_8041060_5 PFAM cytoplasmic chaperone TorD family protein - - - 0.0000000000014 79.0
CH2_k127_8056894_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 7.349e-200 677.0
CH2_k127_8056894_1 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 531.0
CH2_k127_8056894_2 Abc transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 452.0
CH2_k127_8056894_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003561 267.0
CH2_k127_8113046_0 Bacterial extracellular solute-binding protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 443.0
CH2_k127_8113046_1 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 381.0
CH2_k127_8113046_2 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 316.0
CH2_k127_8113046_3 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001831 282.0
CH2_k127_8113046_4 Transcriptional regulator of molybdate metabolism, LysR family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000857 261.0
CH2_k127_8113046_5 TOBE domain - - - 0.0000000000000342 82.0
CH2_k127_8117660_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 6.693e-274 875.0
CH2_k127_8117660_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 549.0
CH2_k127_8117660_2 amino acid K01999 - - 0.000000000000000000000000000000000000000009485 160.0
CH2_k127_8124901_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 4.197e-266 827.0
CH2_k127_8124901_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 6.681e-196 620.0
CH2_k127_8124901_2 FIST N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 338.0
CH2_k127_8124901_3 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 329.0
CH2_k127_8124901_4 MucB/RseB C-terminal domain K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 321.0
CH2_k127_8124901_5 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.000000000000000000000000000000006321 135.0
CH2_k127_8124901_6 Positive regulator of sigma(E), RseC/MucC K03803 - - 0.00000000000000000000000003409 115.0
CH2_k127_8124901_7 - K19168 - - 0.000000178 61.0
CH2_k127_8125062_0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 507.0
CH2_k127_8125062_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0048037,GO:0050136,GO:0050660,GO:0050662,GO:0051179,GO:0051234,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071949,GO:0097159,GO:0098796,GO:1901265,GO:1901363,GO:1902494 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 497.0
CH2_k127_8125062_2 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347,K03614 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 481.0
CH2_k127_8125062_3 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002096 276.0
CH2_k127_8125062_4 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000001957 275.0
CH2_k127_8125062_5 FMN_bind K00348 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000002919 241.0
CH2_k127_8149559_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 6.799e-274 854.0
CH2_k127_8149559_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 402.0
CH2_k127_8149559_2 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000001351 166.0
CH2_k127_8149559_3 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000004442 128.0
CH2_k127_8149559_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000001851 88.0
CH2_k127_8158486_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.84e-300 934.0
CH2_k127_8158486_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 3.322e-235 747.0
CH2_k127_8158486_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 396.0
CH2_k127_8158486_3 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.00000000000000000000000000000000000000000000000000001332 194.0
CH2_k127_8158486_4 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000013 166.0
CH2_k127_8168360_0 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 576.0
CH2_k127_8168360_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000002247 183.0
CH2_k127_8168360_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000002179 158.0
CH2_k127_8168360_3 - - - - 0.0000000000000000000004572 102.0
CH2_k127_8173503_0 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 479.0
CH2_k127_8173503_1 PAS fold - - - 0.0000000000000000000000000000000000005856 149.0
CH2_k127_8175051_0 twitching motility protein K02670 - - 9.621e-196 615.0
CH2_k127_8175051_1 Belongs to the methyltransferase superfamily K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 484.0
CH2_k127_8175051_2 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000147 223.0
CH2_k127_8175051_3 PFAM type II secretion system protein E K02669 - - 0.0000000000000000287 81.0
CH2_k127_8190390_0 LexA DNA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001733 268.0
CH2_k127_8190390_1 endonuclease III K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000002648 240.0
CH2_k127_8190390_2 Belongs to the peptidase M48B family - - - 0.0000000000000000000000000000000000000000000000000000000000003254 220.0
CH2_k127_8190390_3 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.00000000000000000000000000000000000000000000000002279 184.0
CH2_k127_8209964_0 glycyl-tRNA synthetase beta K01879 - 6.1.1.14 1.782e-198 636.0
CH2_k127_8209964_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000003871 105.0
CH2_k127_8214214_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 6.853e-203 636.0
CH2_k127_8214214_1 PFAM Mur ligase middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 507.0
CH2_k127_8214214_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 462.0
CH2_k127_8214214_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 361.0
CH2_k127_8214214_4 Colicin V production K03558 - - 0.000000000000000000000000000000000000006229 151.0
CH2_k127_8214214_5 Sporulation related domain K03749 - - 0.0000000000000000000000000006545 122.0
CH2_k127_8246650_0 Transglutaminase/protease-like homologues K22452 - 2.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 361.0
CH2_k127_8246650_1 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000003549 202.0
CH2_k127_8260597_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 429.0
CH2_k127_8260597_1 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000000003442 194.0
CH2_k127_8270467_0 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 572.0
CH2_k127_8270467_1 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000336 290.0
CH2_k127_8445096_0 abc transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 382.0
CH2_k127_8445096_1 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 382.0
CH2_k127_8445096_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000006321 164.0
CH2_k127_8508231_0 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 593.0
CH2_k127_8508231_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 296.0
CH2_k127_8508231_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000002526 82.0
CH2_k127_8535138_0 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 348.0
CH2_k127_8535138_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000006658 186.0
CH2_k127_8535138_2 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000001575 89.0
CH2_k127_8535138_3 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000002147 84.0
CH2_k127_8564460_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1303.0
CH2_k127_8564460_1 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 301.0
CH2_k127_8564460_2 ABC-type amino acid transport signal transduction systems periplasmic component domain K10001 GO:0003333,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015740,GO:0015800,GO:0015807,GO:0015813,GO:0015849,GO:0015893,GO:0016595,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070335,GO:0070778,GO:0071702,GO:0071705,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000001181 244.0
CH2_k127_8586667_0 Formyl transferase K19640 - - 1.699e-236 744.0
CH2_k127_8586667_1 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000831 223.0
CH2_k127_8586667_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000003353 224.0
CH2_k127_8599507_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 9.791e-316 985.0
CH2_k127_8599507_1 PFAM ATPase associated with various cellular activities, AAA_3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 476.0
CH2_k127_8599507_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005057 256.0
CH2_k127_8599507_3 - K16256 - - 0.00000000000000000000000000000000000002191 162.0
CH2_k127_8599507_4 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000005092 139.0
CH2_k127_8599507_5 von Willebrand factor type A domain K16257 - - 0.00000000000000000000004131 113.0
CH2_k127_8642488_0 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 327.0
CH2_k127_8642488_1 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.00000000003965 73.0
CH2_k127_8653460_0 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 331.0
CH2_k127_8653460_1 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000002947 228.0
CH2_k127_8653460_2 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000001047 143.0
CH2_k127_8653460_3 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000144 87.0
CH2_k127_8732524_0 Belongs to the malate synthase family K01638 - 2.3.3.9 1.254e-280 869.0
CH2_k127_8732524_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 471.0
CH2_k127_8732524_2 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001032 250.0
CH2_k127_8732524_3 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000003086 194.0
CH2_k127_8732524_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000001269 181.0
CH2_k127_8732524_5 Cysteine-rich CWC - - - 0.0000000533 61.0
CH2_k127_8747142_0 Diguanylate cyclase K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 558.0
CH2_k127_8747142_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 326.0
CH2_k127_8747142_2 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 297.0
CH2_k127_8747142_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001758 277.0
CH2_k127_8747142_4 PFAM peptidase M28 - - - 0.00000000000000000000000005288 108.0
CH2_k127_8747142_5 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000001089 74.0
CH2_k127_8781139_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 514.0
CH2_k127_8781139_1 Polyprenyl synthetase K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 306.0
CH2_k127_8781139_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000001591 164.0
CH2_k127_8781139_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000005131 158.0
CH2_k127_8781139_4 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000002546 138.0
CH2_k127_8802454_0 PFAM Transposase, IS111A IS1328 IS1533 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006903 260.0
CH2_k127_8802454_1 PFAM oxidoreductase - - - 0.00000000000000000001784 95.0
CH2_k127_8806289_0 Prolyl oligopeptidase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 356.0
CH2_k127_8806289_1 Protein of unknown function (DUF3025) - - - 0.0000000000000000000000000000000000000000000000000000000000000006409 228.0
CH2_k127_8806289_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000008079 216.0
CH2_k127_8806289_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000000003022 213.0
CH2_k127_8806289_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000001671 92.0
CH2_k127_8806289_5 - - - - 0.000000000000000001195 94.0
CH2_k127_8825187_0 Pregnancy-associated plasma protein-A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 326.0
CH2_k127_8825187_1 hemolysin iii K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 297.0
CH2_k127_8825187_2 - - - - 0.000000000000006625 79.0
CH2_k127_8825187_3 Protein of unknown function (DUF2934) - - - 0.0000000188 61.0
CH2_k127_8825187_4 - - - - 0.0004084 48.0
CH2_k127_8895176_0 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 348.0
CH2_k127_8895176_1 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 308.0
CH2_k127_8895176_2 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000000000000001893 162.0
CH2_k127_8897519_0 Cache 3/Cache 2 fusion domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 476.0
CH2_k127_8897519_1 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 362.0
CH2_k127_8897519_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000004478 243.0
CH2_k127_8897519_3 Protein of unknown function (DUF465) K09794 - - 0.000000000145 64.0
CH2_k127_8926197_0 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05577 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 509.0
CH2_k127_8927927_0 E1 component K00164 - 1.2.4.2 9.362e-252 788.0
CH2_k127_8930693_0 Electron transfer flavoprotein, beta subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 381.0
CH2_k127_8930693_1 Electron transfer flavoprotein alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 364.0
CH2_k127_8930693_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 349.0
CH2_k127_8933679_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 404.0
CH2_k127_8933679_1 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000000000000009924 229.0
CH2_k127_8933679_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.00000000000882 72.0
CH2_k127_8933679_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000006705 57.0
CH2_k127_8939525_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 586.0
CH2_k127_8939525_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 308.0
CH2_k127_8939525_2 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000001495 241.0
CH2_k127_8939525_3 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000000000000000000000000000000000002517 197.0
CH2_k127_8958102_0 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 377.0
CH2_k127_8958102_1 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 327.0
CH2_k127_8958102_2 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002039 245.0
CH2_k127_8958102_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000002543 158.0
CH2_k127_8963250_0 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 288.0
CH2_k127_8963250_1 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003278 273.0
CH2_k127_8963250_2 Bacterial SH3 domain - - - 0.0000000000000000000000306 106.0
CH2_k127_8964360_0 Homospermidine synthase K00808 - 2.5.1.44 9.092e-217 683.0
CH2_k127_8964360_1 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 573.0
CH2_k127_8964360_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 357.0
CH2_k127_8964360_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002497 269.0
CH2_k127_8964360_4 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000006126 266.0
CH2_k127_8964360_5 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000002822 198.0
CH2_k127_8964360_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000007372 182.0
CH2_k127_8964360_7 Belongs to the globin family - - - 0.00000000000000000000000000007706 121.0
CH2_k127_8964360_8 Protein of unknown function (DUF3567) - - - 0.00000000000000287 78.0
CH2_k127_8964360_9 - - - - 0.000146 48.0
CH2_k127_9011494_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 557.0
CH2_k127_9011494_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 326.0
CH2_k127_9011494_2 TRANSCRIPTIONal REGULATOR, GntR family K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004033 269.0
CH2_k127_9011494_3 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000001241 181.0
CH2_k127_9011494_4 NUDIX domain - - - 0.00000000000000000000000000000000000000000000002547 178.0
CH2_k127_9011494_6 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.000000000000000000000000000000000000000000004424 174.0
CH2_k127_9011494_7 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000000000000000000004738 131.0
CH2_k127_9011494_8 COG3187 Heat shock protein K09914 - - 0.00002238 53.0
CH2_k127_9034610_0 Sarcosine oxidase, gamma subunit family K00302 - 1.5.3.1 0.0 1252.0
CH2_k127_9034610_1 Nitronate monooxygenase K22083 - 2.1.1.21 9.076e-257 797.0
CH2_k127_9034610_10 GXGXG motif K22082 - 2.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 304.0
CH2_k127_9034610_11 Sarcosine oxidase, gamma subunit family K00305 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000009841 199.0
CH2_k127_9034610_12 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.00000000000000000000000000000000000000000000000002849 184.0
CH2_k127_9034610_13 Sarcosine oxidase, delta subunit family K00304 - 1.5.3.1 0.0000000000000000000000000000000000001706 143.0
CH2_k127_9034610_14 phosphocarrier protein Hpr K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000004319 138.0
CH2_k127_9034610_2 FAD dependent oxidoreductase K00303,K10816 - 1.4.99.5,1.5.3.1 1.782e-247 769.0
CH2_k127_9034610_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.411e-231 721.0
CH2_k127_9034610_4 Glutamate-cysteine ligase K01919 - 6.3.2.2 2.608e-216 679.0
CH2_k127_9034610_5 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 521.0
CH2_k127_9034610_6 Glutamine amidotransferase domain K22081 - 2.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 499.0
CH2_k127_9034610_7 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 431.0
CH2_k127_9034610_8 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 433.0
CH2_k127_9034610_9 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 403.0
CH2_k127_9035642_0 AAA domain - - - 1.96e-253 797.0
CH2_k127_9035642_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 1.346e-228 716.0
CH2_k127_9035642_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 329.0
CH2_k127_9035642_3 PFAM UspA - - - 0.00000000000000000000000008494 117.0
CH2_k127_9035642_4 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000002826 96.0
CH2_k127_9053302_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 6.997e-194 616.0
CH2_k127_9053302_1 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 430.0
CH2_k127_9053302_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 420.0
CH2_k127_9053302_3 PFAM AFG1-family ATPase K06916 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 400.0
CH2_k127_9053302_4 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 0.0000000000000000000000000000000000000005317 149.0
CH2_k127_9064657_0 Histidine kinase K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 358.0
CH2_k127_9064657_1 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000001044 240.0
CH2_k127_9093147_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 557.0
CH2_k127_9093147_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 370.0
CH2_k127_9093147_2 haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000001036 237.0
CH2_k127_9093147_3 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000001019 208.0
CH2_k127_9165974_0 PFAM Peptidase M16 K07263 - - 6.395e-203 640.0
CH2_k127_9165974_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009101 454.0
CH2_k127_9165974_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 387.0
CH2_k127_9165974_3 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 338.0
CH2_k127_9165974_4 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 306.0
CH2_k127_9165974_5 Peptidase C26 K01658,K07010 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 283.0
CH2_k127_9165974_6 PFAM Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000003397 229.0
CH2_k127_9165974_7 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000128 143.0
CH2_k127_9165974_8 PFAM acyl-coA-binding protein, ACBP - - - 0.000000000000000000000000007305 115.0
CH2_k127_9203577_0 PGAP1-like protein - - - 6.707e-286 885.0
CH2_k127_9203577_1 Aldo/keto reductase family - - - 0.000000000000000000000001072 108.0
CH2_k127_9203577_2 Conserved TM helix - - - 0.000001166 50.0
CH2_k127_9220464_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 516.0
CH2_k127_9220464_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 317.0
CH2_k127_9233224_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.581e-270 842.0
CH2_k127_9233224_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 413.0
CH2_k127_9233224_2 HAD-superfamily hydrolase K01091 - 3.1.3.18 0.00000000000000008377 83.0
CH2_k127_9260803_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 339.0
CH2_k127_9260803_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000003006 259.0
CH2_k127_9260803_2 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000000001319 143.0
CH2_k127_9260803_3 Peptidase S24-like - - - 0.000000000000000000000000000000000005464 141.0
CH2_k127_9260803_4 - - - - 0.00000000000000215 83.0
CH2_k127_9260803_5 - - - - 0.0000000000006517 78.0
CH2_k127_9348150_0 Lipase maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 531.0
CH2_k127_9348150_1 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 385.0
CH2_k127_9348150_2 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 313.0
CH2_k127_9348150_3 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004225 260.0
CH2_k127_9348150_4 Protein of unknown function, DUF599 - - - 0.0000000000000000000000000000000000000000000000000000000000005707 218.0
CH2_k127_9348150_5 promotes GTP-dependent translocation of the ribosome during translation K02355 - - 0.00000000000000000000000000000000000000000000000000002339 190.0
CH2_k127_9348150_6 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000002299 154.0
CH2_k127_9348150_7 - - - - 0.0000000000000000000000000000000004027 133.0
CH2_k127_9348150_8 - - - - 0.000000000000000000000004073 108.0
CH2_k127_9366883_0 DNA topoisomerase, type IA, central K03169 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 436.0
CH2_k127_9366883_1 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 421.0
CH2_k127_9367679_0 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 557.0
CH2_k127_9367679_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007303 471.0
CH2_k127_9367679_10 - - - - 0.00000000002853 67.0
CH2_k127_9367679_11 High-affinity nickel-transport protein K07241 - - 0.00000002248 56.0
CH2_k127_9367679_12 - - - - 0.00004705 51.0
CH2_k127_9367679_2 Site-specific recombinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 461.0
CH2_k127_9367679_3 His Kinase A (phosphoacceptor) domain K02484,K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 370.0
CH2_k127_9367679_4 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 351.0
CH2_k127_9367679_5 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 297.0
CH2_k127_9367679_6 Poly(3-hydroxyalkanoate) synthetase - - - 0.00000000000000000000000000000000000000000000000000000000005813 209.0
CH2_k127_9367679_7 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000009294 139.0
CH2_k127_9367679_8 - - - - 0.000000000000000002678 91.0
CH2_k127_9367679_9 - - - - 0.0000000000000003361 81.0
CH2_k127_9369211_0 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 460.0
CH2_k127_9369211_1 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 390.0
CH2_k127_9369211_2 Iron-sulfur cluster-binding domain K06139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 302.0
CH2_k127_9379357_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 6.722e-277 858.0
CH2_k127_9379357_1 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 519.0
CH2_k127_9379357_2 - - - - 0.0002252 49.0
CH2_k127_9387223_0 DHH family K07462 - - 6.131e-218 689.0
CH2_k127_9387223_1 Belongs to the peptidase S16 family - - - 0.000000000000000000000000000000000000000000000000000000000007495 216.0
CH2_k127_9387223_2 membrane - - - 0.000000000000003498 79.0
CH2_k127_939768_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 424.0
CH2_k127_939768_1 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000001876 197.0
CH2_k127_9411249_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 541.0
CH2_k127_9411249_1 PFAM NnrS family protein K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 534.0
CH2_k127_9411249_2 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.000000000000000000000000000000000000000000000000000000000001648 214.0
CH2_k127_9411249_3 - - - - 0.00000000000000000000000000000000000000007408 156.0
CH2_k127_9411249_4 AP2 domain - - - 0.000000000000000002344 91.0
CH2_k127_9411249_5 PIN domain - - - 0.00000000001896 66.0
CH2_k127_943391_0 DNA polymerase III K02342 - 2.7.7.7 5.773e-238 756.0
CH2_k127_943391_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 538.0
CH2_k127_943391_2 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000005226 178.0
CH2_k127_943391_3 His Kinase A (phospho-acceptor) domain - - - 0.000000000000000000000000000000000000001946 149.0
CH2_k127_9435130_0 permease K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 392.0
CH2_k127_9435130_1 Excalibur calcium-binding domain - - - 0.0000000000000000000000000000000000000000001516 164.0
CH2_k127_9435130_2 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000000000002243 140.0
CH2_k127_9435130_4 nitrogen regulatory protein P-II - - - 0.0000000000000000916 83.0
CH2_k127_9435130_6 ChrR Cupin-like domain - - - 0.0000395 46.0
CH2_k127_9436026_0 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 297.0
CH2_k127_9436026_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000027 213.0
CH2_k127_9436026_2 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000003867 203.0
CH2_k127_9436026_3 MazG-like family - - - 0.000000000000000000000000000000000009512 139.0
CH2_k127_9436026_4 diguanylate cyclase - - - 0.000000000004497 78.0
CH2_k127_9436026_5 lipolytic protein G-D-S-L family - - - 0.00000000000881 75.0
CH2_k127_9436026_6 TGS domain K06944 - - 0.0000000001072 72.0
CH2_k127_9442296_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1039.0
CH2_k127_9442296_1 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 468.0
CH2_k127_9442296_2 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 301.0
CH2_k127_9442296_3 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000002768 61.0
CH2_k127_9450900_0 TIGRFAM TIGR03032 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 548.0
CH2_k127_9453885_0 PFAM ABC-1 domain protein K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 549.0
CH2_k127_9453885_1 - - - - 0.00000000000000000000000000000002563 130.0
CH2_k127_9458099_0 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 1.649e-242 761.0
CH2_k127_9458099_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 3.185e-218 684.0
CH2_k127_9458099_2 PFAM type II secretion system K02653 - - 1.105e-205 646.0
CH2_k127_9458099_3 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 381.0
CH2_k127_9458099_4 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 391.0
CH2_k127_9458099_5 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 365.0
CH2_k127_9458099_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000008695 176.0
CH2_k127_9458099_7 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000001664 134.0
CH2_k127_9458099_8 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00004851 46.0
CH2_k127_9458099_9 - - - - 0.00007813 49.0
CH2_k127_946330_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 425.0
CH2_k127_946330_1 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000001534 243.0
CH2_k127_946330_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000001553 218.0
CH2_k127_946330_3 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000000000000000000006849 178.0
CH2_k127_946330_4 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.0000000000000000000000000000000000000006177 153.0
CH2_k127_946330_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000000009792 128.0
CH2_k127_946330_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000001995 109.0
CH2_k127_9469658_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.914e-226 709.0
CH2_k127_9469658_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 344.0
CH2_k127_9469658_2 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000000000000000000000000000001632 233.0
CH2_k127_9469658_3 Domain of unknown function DUF123 - - - 0.0000000000000000000000000000000000000000007337 159.0
CH2_k127_9471059_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 411.0
CH2_k127_9471059_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 399.0
CH2_k127_9471059_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000008673 163.0
CH2_k127_9477641_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 9.971e-248 771.0
CH2_k127_9477641_1 Protein of unknown function (DUF465) - - - 0.000000000000000968 82.0
CH2_k127_9478713_0 Sulfate transporter antisigma-factor antagonist STAS - - - 1.191e-300 936.0
CH2_k127_9478713_1 Sulfate permease family K03321 - - 3.007e-233 738.0
CH2_k127_9478713_2 Chromate K07240 - - 2.245e-196 627.0
CH2_k127_9478713_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 2.937e-195 620.0
CH2_k127_9478713_4 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 551.0
CH2_k127_9480113_0 Alpha beta hydrolase K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000002072 250.0
CH2_k127_9480113_1 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000002392 192.0
CH2_k127_9480113_2 Belongs to the peptidase M48B family K03799 - - 0.00000002047 56.0
CH2_k127_9502710_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1647.0
CH2_k127_9502710_1 Copper binding periplasmic protein CusF K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 478.0
CH2_k127_9502710_2 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000001398 171.0
CH2_k127_9543213_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 419.0
CH2_k127_9543213_1 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 379.0
CH2_k127_9543213_2 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009918 274.0
CH2_k127_9543213_3 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000001201 195.0
CH2_k127_9543213_4 FR47-like protein - - - 0.00000000000000000000000000000000000000000002076 168.0
CH2_k127_9543213_5 SMART CoA-binding domain protein K06929 - - 0.0000000000000000000000000000000000000000002016 170.0
CH2_k127_9543213_6 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000008876 97.0
CH2_k127_9544104_0 Cation transport ATPase (P-type) K01537 - 3.6.3.8 0.0 1043.0
CH2_k127_9544104_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000002308 119.0
CH2_k127_9544104_2 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.000000000000000000000004144 102.0
CH2_k127_9548864_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 451.0
CH2_k127_9548864_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008921 435.0
CH2_k127_9548864_2 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 330.0
CH2_k127_9548864_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 319.0
CH2_k127_9548864_4 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000003409 199.0
CH2_k127_9593911_0 cheY-homologous receiver domain K02657 - - 0.00000000000000000000000000000000000000000000000000000000000000001285 226.0
CH2_k127_9593911_1 response regulator receiver K02658 - - 0.000000000000000000000000000000000000000000000000000002023 199.0
CH2_k127_9593911_2 PFAM CheW domain protein K02659 - - 0.0000000000000000000000000000000000000000001322 166.0
CH2_k127_9593911_3 chemotaxis K02660 - - 0.000000000000003763 82.0
CH2_k127_9687272_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 301.0
CH2_k127_9687272_1 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 290.0
CH2_k127_9687272_2 Beta-lactamase enzyme family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000001736 230.0
CH2_k127_969993_0 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 548.0
CH2_k127_969993_1 Glutathione S-transferase, N-terminal domain K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 351.0
CH2_k127_969993_2 Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 290.0
CH2_k127_969993_3 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000271 254.0
CH2_k127_969993_4 stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000001576 158.0
CH2_k127_969993_5 Sensors of blue-light using FAD - - - 0.0000000000000000006702 92.0
CH2_k127_969993_6 Amino-transferase class IV K03342 - 2.6.1.85,4.1.3.38 0.000000003315 61.0
CH2_k127_969993_7 - - - - 0.000002014 51.0
CH2_k127_9719707_0 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 306.0
CH2_k127_9719707_1 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000000000000253 243.0
CH2_k127_9719707_2 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000001135 219.0
CH2_k127_9775364_0 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 560.0
CH2_k127_9775364_1 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 299.0
CH2_k127_9775364_2 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000001378 156.0
CH2_k127_9828693_0 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 471.0
CH2_k127_9828693_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 395.0
CH2_k127_9828693_2 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000001043 167.0
CH2_k127_9830538_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000801 381.0
CH2_k127_9830538_1 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001234 271.0
CH2_k127_9830538_2 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000000000000001074 215.0
CH2_k127_9830538_3 PFAM CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000002157 164.0
CH2_k127_9830538_4 hydrogenase maturation protease - - - 0.0000000000000000000000000000000000000000009014 163.0
CH2_k127_9830538_5 AAA domain K07028 - - 0.00000000000000000000000002201 112.0
CH2_k127_9830538_6 Protein of unknown function (DUF504) - - - 0.0000000000000000000000993 101.0
CH2_k127_983177_0 4Fe-4S dicluster domain K18930 - - 4.13e-270 848.0
CH2_k127_983177_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000001744 196.0
CH2_k127_983177_2 Protein of unknown function (DUF3568) - - - 0.00000000000000000000000000001211 122.0
CH2_k127_983177_3 - - - - 0.00000000000000000001236 103.0
CH2_k127_9837551_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 5.214e-241 755.0
CH2_k127_9837551_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 2.656e-221 705.0
CH2_k127_9837551_10 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000001947 160.0
CH2_k127_9837551_11 von Willebrand factor (vWF) type A domain K02448 - - 0.000000000000000000000008898 100.0
CH2_k127_9837551_12 KTSC domain - - - 0.000000000000004533 79.0
CH2_k127_9837551_2 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 347.0
CH2_k127_9837551_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 325.0
CH2_k127_9837551_4 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 307.0
CH2_k127_9837551_5 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 301.0
CH2_k127_9837551_6 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004425 287.0
CH2_k127_9837551_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001242 270.0
CH2_k127_9837551_8 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000009535 201.0
CH2_k127_9837551_9 MaoC like domain - - - 0.0000000000000000000000000000000000000000001433 163.0
CH2_k127_9838997_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 362.0
CH2_k127_9838997_1 FixH K09926 - - 0.0000000000000000000000000000000000000000004765 164.0
CH2_k127_9838997_2 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000003183 151.0
CH2_k127_9838997_3 - - - - 0.0000000000000000000003296 99.0
CH2_k127_9838997_4 Protein of unknown function (DUF3149) - - - 0.000004807 51.0
CH2_k127_9840255_0 Transport of potassium into the cell K03549 - - 2.209e-272 860.0
CH2_k127_9840255_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 433.0
CH2_k127_9840255_2 HemX, putative uroporphyrinogen-III C-methyltransferase K02496 - 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 317.0
CH2_k127_9840255_3 uroporphyrinogen III synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 299.0
CH2_k127_9840255_4 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000002242 228.0
CH2_k127_9840255_5 Thioredoxin-like domain - - - 0.0000000000000000000000000000009261 129.0
CH2_k127_9840255_6 response regulator K08083 - - 0.000000000000000000000000001179 113.0
CH2_k127_9843860_0 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 472.0
CH2_k127_9843860_1 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 449.0
CH2_k127_9843860_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000001879 111.0
CH2_k127_9849992_0 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 549.0
CH2_k127_9849992_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 365.0
CH2_k127_9849992_2 Pfam Fatty acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001044 248.0
CH2_k127_9849992_3 - - - - 0.0000000000000001869 85.0
CH2_k127_9851962_0 Pfam:N_methyl_2 K02456 - - 0.00000000000000000000000000000000000000000000000000000004747 207.0
CH2_k127_9851962_1 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000004654 171.0
CH2_k127_9851962_2 Type II secretory pathway, pseudopilin - - - 0.0000000000000000000000000000000000001708 156.0
CH2_k127_9851962_3 Cohesin domain K02453 - - 0.000000000000000005583 89.0
CH2_k127_9856678_0 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 300.0
CH2_k127_9856678_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005866 258.0
CH2_k127_9856678_2 Domain of unknown function (DUF4149) - - - 0.000000000000000000000000000000000000000006366 159.0
CH2_k127_9856678_3 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 - - 0.000000002223 60.0
CH2_k127_9860056_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 372.0
CH2_k127_9860056_1 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000001313 254.0
CH2_k127_9862345_0 PFAM Carbamoyl-phosphate synthase L chain ATP-binding K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 8.012e-197 617.0
CH2_k127_9862345_1 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 308.0
CH2_k127_9862345_2 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000002842 261.0
CH2_k127_9862345_3 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000003988 168.0
CH2_k127_9862705_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 5.367e-296 913.0
CH2_k127_9866714_0 Multicopper oxidase K22349 - 1.16.3.3 1.397e-309 968.0
CH2_k127_9883275_0 Aminotransferase class I and II K00832 - 2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 558.0
CH2_k127_9883275_1 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000746 121.0
CH2_k127_9949820_0 PFAM ABC transporter K06158 - - 1.896e-231 737.0
CH2_k127_9949820_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 549.0
CH2_k127_9949820_2 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 530.0
CH2_k127_9949820_3 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 436.0
CH2_k127_9949820_4 COG2755 Lysophospholipase L1 and related esterases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000016 259.0
CH2_k127_9949820_5 Membrane - - - 0.00000000000000000000000000000000000000000000000000000006705 216.0
CH2_k127_9949820_6 Protein kinase domain K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.0000000000000000000000002781 122.0
CH2_k127_9949820_7 - - - - 0.0000000000000004637 89.0
CH2_k127_9967435_0 PFAM HupH hydrogenase expression protein K03618 - - 0.000000000000000000000000000000000000000000000000000000000000000000008691 243.0
CH2_k127_9967435_1 Ni,Fe-hydrogenase I large subunit - - - 0.0000000000000000000000000000000000000006838 162.0
CH2_k127_9967435_2 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.0000000000000000000000000000004638 131.0
CH2_k127_9967435_3 Rubredoxin - - - 0.0000000000000000000007008 109.0
CH2_k127_9967435_4 Hydrogenase-1 expression protein HyaE K03619 - - 0.000000003151 59.0
CH2_k127_997141_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1061.0
CH2_k127_997141_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 3.485e-232 724.0
CH2_k127_997141_10 - - - - 0.0000000002739 66.0
CH2_k127_997141_2 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 571.0
CH2_k127_997141_3 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005601 293.0
CH2_k127_997141_4 Transferase hexapeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000002727 228.0
CH2_k127_997141_5 Haem-degrading - - - 0.000000000000000000000000000000000000000006214 159.0
CH2_k127_997141_6 AsmA family K07289,K07290 - - 0.0000000000000000000000000172 119.0
CH2_k127_997141_7 Las17-binding protein actin regulator - - - 0.000000000000000000003099 100.0
CH2_k127_997141_8 - - - - 0.00000000000000000006695 91.0
CH2_k127_997141_9 - - - - 0.0000000000001028 74.0
CH2_k127_9992646_0 COG0474 Cation transport ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 609.0
CH2_k127_9992646_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000001975 92.0