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Overview

ID MAG00265
Name CH2_bin.9
Sample SMP0008
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Xanthomonadales
Family Ahniellaceae
Genus JADKHK01
Species
Assembly information
Completeness (%) 74.08
Contamination (%) 2.42
GC content (%) 63.0
N50 (bp) 4,075
Genome size (bp) 2,747,327

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2723

Gene name Description KEGG GOs EC E-value Score Sequence
CH2_k127_10001849_0 PhoD-like phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 480.0
CH2_k127_10001849_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 467.0
CH2_k127_10001849_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 423.0
CH2_k127_10001849_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 410.0
CH2_k127_10001849_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000001053 166.0
CH2_k127_10001849_5 Belongs to the ArsC family - - - 0.000000000000000000000000000000007858 139.0
CH2_k127_10001849_6 Arc-like DNA binding domain - - - 0.0000000000000000000007638 98.0
CH2_k127_10001849_7 Protein of unknown function (DUF3592) - - - 0.00000000216 66.0
CH2_k127_10003319_0 Acetolactate synthase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 462.0
CH2_k127_10003319_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000003413 148.0
CH2_k127_10003319_2 acetolactate synthase activity K01653,K11258 GO:0003674,GO:0003824,GO:0003984,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.2.1.6 0.000000008064 61.0
CH2_k127_10025136_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000107 269.0
CH2_k127_10025136_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000009827 213.0
CH2_k127_10026312_0 transport protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 458.0
CH2_k127_10026312_1 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 323.0
CH2_k127_10026312_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000008187 188.0
CH2_k127_10026312_3 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000000001107 159.0
CH2_k127_10026312_4 SpoVT / AbrB like domain K07172 - - 0.0000000000000000003999 90.0
CH2_k127_10033878_0 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 554.0
CH2_k127_10033878_1 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 476.0
CH2_k127_10033878_2 arylsulfatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 326.0
CH2_k127_10033878_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001173 233.0
CH2_k127_10033878_4 - - - - 0.0000000000000000000000000000000000000000000000000000000003101 211.0
CH2_k127_10033878_5 Cadherin repeats. - - - 0.00000000000000000000000000000000000005808 158.0
CH2_k127_10033878_6 - - - - 0.000000000000000000001884 104.0
CH2_k127_1003688_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0000000000000000000000000000000000000000001991 161.0
CH2_k127_1003688_1 Kdo2-lipid A biosynthetic process - - - 0.0000000000000000000000000000000000000000005666 173.0
CH2_k127_1003688_2 metallopeptidase activity K16922 - - 0.00000000000000000000000000000000002167 151.0
CH2_k127_10085798_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 337.0
CH2_k127_10085798_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 316.0
CH2_k127_10085798_2 Diguanylate cyclase K08968 - 1.8.4.14 0.0000000000000000000000000000000000000000000000000000000000000000007043 232.0
CH2_k127_10085798_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.000000000000000000000000000000000000000000000000000000002441 207.0
CH2_k127_10091344_0 periplasmic ligand-binding sensor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 604.0
CH2_k127_10099343_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 385.0
CH2_k127_10099343_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00003453 46.0
CH2_k127_10178868_0 Lamin Tail Domain K07004 - - 0.000000000000000000000000000000000000000000000000000000000001059 226.0
CH2_k127_10178868_1 Gaf domain - - - 0.0000000000000003712 81.0
CH2_k127_10201574_0 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 423.0
CH2_k127_10201574_1 phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 359.0
CH2_k127_10201574_2 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 311.0
CH2_k127_10201574_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000002249 268.0
CH2_k127_10201574_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000001482 219.0
CH2_k127_10201574_5 Autotransporter beta-domain - - - 0.0000000000000000000000001009 109.0
CH2_k127_10201574_6 Methyltransferase domain - - - 0.000009817 54.0
CH2_k127_1021138_0 Globin - - - 0.000000000000000000000000000000000006425 148.0
CH2_k127_1021138_1 diguanylate cyclase - - - 0.000000000000000000000000000000001802 137.0
CH2_k127_10238900_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 2.951e-248 771.0
CH2_k127_10238900_1 S-layer homology domain - - - 0.000000000000006732 89.0
CH2_k127_10238900_2 gluconolactonase activity - - - 0.0000000000157 78.0
CH2_k127_10238976_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1054.0
CH2_k127_10238976_1 Type II/IV secretion system protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 560.0
CH2_k127_10238976_2 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 548.0
CH2_k127_10238976_3 PFAM UbiA prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004913 236.0
CH2_k127_10238976_4 Membrane K07148 - - 0.000000000000000000000000000000000000000000000000000000000000001101 234.0
CH2_k127_10238976_5 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000003574 162.0
CH2_k127_10238976_6 Tetratricopeptide repeat - - - 0.000000000000005535 89.0
CH2_k127_10238976_7 dextransucrase activity - - - 0.0000000000001481 84.0
CH2_k127_10238976_9 - - - - 0.000001224 55.0
CH2_k127_10250543_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000002568 173.0
CH2_k127_10250543_1 diguanylate cyclase - - - 0.0000000000001164 81.0
CH2_k127_10296743_0 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 316.0
CH2_k127_10296743_1 MerR HTH family regulatory protein - - - 0.0000000000000000000000000000002634 127.0
CH2_k127_10305460_0 ECF sigma factor - - - 0.000000000000000003324 87.0
CH2_k127_10327059_0 membrane - - - 0.0000000000000000000000000000000000000000005538 170.0
CH2_k127_10327059_1 twitching motility protein K02670 - - 0.0000000000000000000000000003564 119.0
CH2_k127_10327059_2 Protein of unknown function (DUF465) - - - 0.000000000000000003075 87.0
CH2_k127_10327059_3 Domain of unknown function (DUF4398) - - - 0.00000005346 60.0
CH2_k127_10334798_0 ABC transporter substrate-binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009923 406.0
CH2_k127_10334798_1 Diguanylate cyclase - - - 0.0000000000000000000000002857 116.0
CH2_k127_10334798_2 VIT family - - - 0.000000000000004894 75.0
CH2_k127_10338915_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1075.0
CH2_k127_10338915_1 - - - - 6.781e-312 1004.0
CH2_k127_10338915_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 5.69e-242 756.0
CH2_k127_10338915_3 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006226 249.0
CH2_k127_10338915_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000002691 204.0
CH2_k127_10357417_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 508.0
CH2_k127_10357417_1 transport system permease component - - - 0.00000000000000000000000000000000000000000000000000000003602 207.0
CH2_k127_10357417_2 Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - 0.00000000007885 66.0
CH2_k127_10373995_0 FAD binding domain K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 467.0
CH2_k127_10373995_1 catalyzes a condensation reaction in fatty acid biosynthesis addition of an acyl acceptor of two carbons from malonyl-ACP K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 416.0
CH2_k127_10373995_2 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 289.0
CH2_k127_10373995_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000007664 110.0
CH2_k127_10373995_4 RES - - - 0.000000005438 59.0
CH2_k127_10381061_0 alcohol dehydrogenase K12957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 432.0
CH2_k127_10381061_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 364.0
CH2_k127_10381061_2 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000004834 61.0
CH2_k127_10381061_3 Bacterial Ig-like domain (group 3) - - - 0.000005493 53.0
CH2_k127_10410883_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 506.0
CH2_k127_10410883_1 Amino acid permease K03759 - - 0.00000000000000000000000000000000000000000003434 169.0
CH2_k127_10410883_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000134 59.0
CH2_k127_10410883_3 Microcystin-dependent protein - - - 0.00001955 52.0
CH2_k127_10447512_0 Cytochrome C biogenesis K02198 - - 1.304e-203 649.0
CH2_k127_10447512_1 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000009753 172.0
CH2_k127_10447512_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000006862 79.0
CH2_k127_1044866_0 Activates the expression of a regulon of hydrogen peroxide-inducible genes such as katG, gor, ahpC, ahpF, oxyS, dps, fur and grxA K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 389.0
CH2_k127_1044866_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 304.0
CH2_k127_1044866_2 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000009305 239.0
CH2_k127_1044866_3 Ion transport protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000008768 214.0
CH2_k127_1044866_4 Permease for cytosine/purines, uracil, thiamine, allantoin K03457,K10975 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0015205,GO:0015851,GO:0016020,GO:0022857,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000004973 132.0
CH2_k127_1044866_5 Inner membrane protein CreD - - - 0.0000000001905 72.0
CH2_k127_104524_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1545.0
CH2_k127_104524_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000002363 160.0
CH2_k127_10454974_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 1.73e-225 717.0
CH2_k127_10454974_1 oxidase, subunit II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 436.0
CH2_k127_10454974_2 oxidase, subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 317.0
CH2_k127_10454974_3 PkhD-type hydroxylase K07336 - - 0.0000000000000000000000000000000000000000000000000000000001874 214.0
CH2_k127_10454974_4 Domain of unknown function (DUF4347) K20276 - - 0.0000000000001104 79.0
CH2_k127_1046523_0 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 437.0
CH2_k127_10487469_0 TIGRFAM PAS domain S-box K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000006971 169.0
CH2_k127_10498312_0 Protein of unknown function (DUF2884) - - - 0.000000000000000000000000000002256 130.0
CH2_k127_10498312_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000263 111.0
CH2_k127_10498312_2 membrane protein domain - - - 0.000000000000000000003687 97.0
CH2_k127_10500349_0 NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1052.0
CH2_k127_10532546_0 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 528.0
CH2_k127_10532546_1 Transporter K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 356.0
CH2_k127_10532546_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000009216 242.0
CH2_k127_10532546_3 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000002602 217.0
CH2_k127_10532546_4 dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000003583 206.0
CH2_k127_10532546_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000004285 182.0
CH2_k127_10532546_6 OsmC-like protein - - - 0.0000000000000000000000000000000000000000005862 165.0
CH2_k127_10532546_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000004268 163.0
CH2_k127_10532546_8 - - - - 0.00000000000000004507 85.0
CH2_k127_10538693_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 334.0
CH2_k127_10538693_1 Glycosyl transferase K20444 - - 0.00000000000000001315 92.0
CH2_k127_10542547_0 Stage II sporulation protein E (SpoIIE) - - - 0.00000000000737 78.0
CH2_k127_10542547_1 (FHA) domain - - - 0.0000002298 63.0
CH2_k127_10542547_2 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0000002378 55.0
CH2_k127_1055308_0 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488,K21053 - 3.5.4.2,3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 489.0
CH2_k127_1055308_1 Preprotein translocase subunit TatD K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 378.0
CH2_k127_1055308_2 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 371.0
CH2_k127_1055308_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 327.0
CH2_k127_1055308_4 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.000000000000000000000000000000000000000002842 159.0
CH2_k127_1055308_5 Protein tyrosine kinase - - - 0.000000000000000000000000000000000008301 154.0
CH2_k127_1055308_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000003222 66.0
CH2_k127_10566586_0 hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 282.0
CH2_k127_10566586_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000007467 248.0
CH2_k127_10580577_0 aminopeptidase - - - 2.175e-199 639.0
CH2_k127_10580577_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 371.0
CH2_k127_10580577_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000009913 58.0
CH2_k127_1058097_0 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 502.0
CH2_k127_1058097_1 Catalyzes the hydrolysis of AMP to form adenine and ribose 5-phosphate using water as the nucleophile K01241 - 3.2.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 463.0
CH2_k127_1058097_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 381.0
CH2_k127_1058097_3 - - - - 0.00007977 49.0
CH2_k127_10601810_0 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000001836 209.0
CH2_k127_10601810_1 MerC mercury resistance protein - - - 0.00000000000000000002344 98.0
CH2_k127_10601810_2 Ribosomal protein S31e K19033 - - 0.0005679 45.0
CH2_k127_10635111_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005436 275.0
CH2_k127_10635111_1 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001213 257.0
CH2_k127_10635111_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000002568 253.0
CH2_k127_10635111_3 MucB/RseB C-terminal domain K03598 - - 0.00000000000000001297 94.0
CH2_k127_10635111_4 Anti sigma-E protein RseA, N-terminal domain - - - 0.0000000000000001292 88.0
CH2_k127_10640915_0 Amidohydrolase family - - - 1.483e-265 825.0
CH2_k127_10649806_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 325.0
CH2_k127_10664542_0 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 344.0
CH2_k127_10664542_1 peptidase activity, acting on L-amino acid peptides K07752 - 3.4.17.22 0.000000000000000000000000000000000000000000000000003297 202.0
CH2_k127_10664542_2 Alpha/beta hydrolase family - - - 0.0002999 44.0
CH2_k127_10667781_0 phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 482.0
CH2_k127_10667781_1 Pit accessory protein K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008792 280.0
CH2_k127_10667781_2 Domain of unknown function DUF21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000403 229.0
CH2_k127_10669063_0 ATP-binding protein K06915 - - 5.196e-209 658.0
CH2_k127_10669063_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003939 255.0
CH2_k127_10669063_2 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.000000000000000000000000000000000000000000000000000000000000008804 226.0
CH2_k127_10686693_0 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 317.0
CH2_k127_10686693_1 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.000000000000001182 82.0
CH2_k127_10686693_2 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.0000000008855 65.0
CH2_k127_10686693_3 involved in intracellular sulfur reduction K07235 - - 0.0000000229 60.0
CH2_k127_10686693_4 Belongs to the DsrF TusC family K07236 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.000393 48.0
CH2_k127_10704379_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 595.0
CH2_k127_10704379_1 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000001382 205.0
CH2_k127_10704379_2 - - - - 0.00000000000000000000000000000000000000000000000000000009565 199.0
CH2_k127_10704379_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000812 162.0
CH2_k127_10712241_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.018e-242 766.0
CH2_k127_10712241_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000004416 237.0
CH2_k127_10712241_2 - - - - 0.00000007265 61.0
CH2_k127_10719017_0 LVIVD repeat - - - 0.0 1553.0
CH2_k127_10739470_0 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 342.0
CH2_k127_10739470_1 synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000002697 274.0
CH2_k127_10739470_2 NAD FAD-binding protein K06954 - - 0.00000000000000000005013 89.0
CH2_k127_10813990_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0 1501.0
CH2_k127_10813990_1 General secretion pathway protein K02454 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 9.917e-282 875.0
CH2_k127_10813990_2 General secretion pathway protein K02455 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0032940,GO:0033036,GO:0042886,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098776 - 0.000000000000000000000003263 104.0
CH2_k127_10813990_3 - - - - 0.00000000001109 74.0
CH2_k127_10848930_0 Protein of unknown function (DUF1631) - - - 0.0000000243 59.0
CH2_k127_10848930_1 Protein of unknown function (DUF1631) - - - 0.000000151 62.0
CH2_k127_10850731_0 Sortilin, neurotensin receptor 3, - - - 7.11e-286 912.0
CH2_k127_10850731_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 553.0
CH2_k127_10850731_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 376.0
CH2_k127_10850731_3 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 332.0
CH2_k127_10850731_4 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) K01083 - 3.1.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000004018 257.0
CH2_k127_10850731_5 Domain of unknown function (DUF4215) - - - 0.000000000000000000000000000000000000000000000000000000000000312 237.0
CH2_k127_10850731_6 Invasion gene expression up-regulator, SirB - - - 0.0000000000000000000000009185 113.0
CH2_k127_10871455_0 Belongs to the aldehyde dehydrogenase family K00130,K00151,K10217 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0008802,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 3.977e-212 668.0
CH2_k127_10871455_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 322.0
CH2_k127_10871455_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004105 280.0
CH2_k127_10890096_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 548.0
CH2_k127_10890096_1 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 416.0
CH2_k127_10890096_2 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 405.0
CH2_k127_10890096_3 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 374.0
CH2_k127_10890096_4 efflux transmembrane transporter activity K02004 - - 0.0000000000000004033 84.0
CH2_k127_1091154_0 Lipoprotein releasing system transmembrane protein K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 499.0
CH2_k127_1091154_1 Serine dehydrogenase proteinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 313.0
CH2_k127_1091154_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 296.0
CH2_k127_1091154_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000007729 239.0
CH2_k127_1091154_4 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000817 184.0
CH2_k127_1091154_5 17 kDa outer membrane surface antigen - - - 0.000000000000000000000000000002066 128.0
CH2_k127_1091154_6 EF-hand, calcium binding motif - - - 0.0005941 48.0
CH2_k127_10938594_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 593.0
CH2_k127_10938594_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 393.0
CH2_k127_10958886_0 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.00000000000000000000001441 114.0
CH2_k127_10969505_0 3-phytase (myo-inositol-hexaphosphate 3-phosphohydrolase) K01083 - 3.1.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 301.0
CH2_k127_10969505_1 CHAD - - - 0.0000000000000000000000000000000000000000003472 168.0
CH2_k127_10979856_0 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000005711 74.0
CH2_k127_10989130_0 desaturase K00508 - 1.14.19.3 1.351e-199 625.0
CH2_k127_10989130_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 541.0
CH2_k127_10989130_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 497.0
CH2_k127_10989130_3 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 487.0
CH2_k127_10989130_4 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 397.0
CH2_k127_10989130_5 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 343.0
CH2_k127_10989130_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0000000000000000000000000000000000000000000003448 169.0
CH2_k127_10989130_7 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.00000000000000004661 94.0
CH2_k127_10989130_8 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000006252 58.0
CH2_k127_11002808_0 Saccharopine dehydrogenase NADP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007315 443.0
CH2_k127_11002808_1 translation initiation inhibitor, yjgF family K04782 - 4.2.99.21 0.000000000000000000000000000000000000000001009 163.0
CH2_k127_11002808_2 UPF0114 protein - - - 0.0000003262 52.0
CH2_k127_11005052_0 MFS transporter K11381 - 1.2.4.4 0.0 1197.0
CH2_k127_11005052_1 deiminase K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000007617 236.0
CH2_k127_11005052_2 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000001426 173.0
CH2_k127_11009272_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 310.0
CH2_k127_11009272_1 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 291.0
CH2_k127_11009272_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001055 259.0
CH2_k127_11009272_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000572 181.0
CH2_k127_11009272_4 phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000003071 147.0
CH2_k127_11015975_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1077.0
CH2_k127_11015975_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000001356 183.0
CH2_k127_11018078_0 Ammonium transporter K03320 - - 2.356e-219 687.0
CH2_k127_11018078_1 asparaginase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000134 279.0
CH2_k127_11018078_2 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000000004106 207.0
CH2_k127_11034459_0 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 353.0
CH2_k127_11034459_1 Ethylbenzene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 329.0
CH2_k127_11034459_2 Cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000001145 216.0
CH2_k127_11034459_4 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000005881 148.0
CH2_k127_11053299_0 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 544.0
CH2_k127_11053299_1 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000009136 121.0
CH2_k127_11053299_2 Histidine kinase-like ATPase domain - - - 0.000000001006 65.0
CH2_k127_11053299_3 Conserved repeat domain - - - 0.00005264 55.0
CH2_k127_11100044_0 secondary active sulfate transmembrane transporter activity K06901 - - 1.097e-204 654.0
CH2_k127_11100044_1 Fad dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 394.0
CH2_k127_1111749_0 Protein of unknown function (DUF1298) - - - 1.991e-210 663.0
CH2_k127_1111749_1 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 581.0
CH2_k127_1111749_2 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001374 258.0
CH2_k127_1111749_3 Transport permease protein K01992 - - 0.00000000000000000000000000003549 119.0
CH2_k127_1111749_4 Protein of unknown function (DUF1444) - - - 0.0001609 47.0
CH2_k127_11123445_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 8.818e-198 624.0
CH2_k127_11123445_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 285.0
CH2_k127_11123445_2 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000000000000001985 214.0
CH2_k127_11123445_3 Dak2 K07030 - - 0.000000000000000000000000000000000000000000001405 171.0
CH2_k127_11124782_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.785e-290 896.0
CH2_k127_11124782_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002292 270.0
CH2_k127_11124782_2 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000002281 213.0
CH2_k127_11156731_0 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 308.0
CH2_k127_11156731_1 Belongs to the agmatine deiminase family - - - 0.000000000000000000000000000000000000000000001674 168.0
CH2_k127_11156731_2 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000004459 121.0
CH2_k127_11156731_3 - - - - 0.000000000000000000007461 95.0
CH2_k127_11174463_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005535 282.0
CH2_k127_11174463_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.00000000000000000000000000000000000000000000000000000000000000004808 225.0
CH2_k127_11180464_0 COG0477 Permeases of the major facilitator superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 544.0
CH2_k127_11180464_1 DNA-(Apurinic or apyrimidinic site) lyase K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 423.0
CH2_k127_11180464_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 426.0
CH2_k127_11180464_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 290.0
CH2_k127_11180464_4 membrane - - - 0.0000000000000000000000000000000000000000000000000004211 188.0
CH2_k127_11180464_5 Domain of unknown function (DUF4124) - - - 0.000000000000000000005138 101.0
CH2_k127_11180464_7 - - - - 0.00000000004846 66.0
CH2_k127_1120278_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 508.0
CH2_k127_1120278_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 488.0
CH2_k127_1120278_2 Fic/DOC family - - - 0.00000000000000000000000000000004382 129.0
CH2_k127_1120278_3 Fic/DOC family - - - 0.000000000000000000245 91.0
CH2_k127_11208745_0 EAL domain K21973 - - 0.0000000000001126 71.0
CH2_k127_11208745_1 Parallel beta-helix repeats - - - 0.00000002003 67.0
CH2_k127_11208745_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0004132 43.0
CH2_k127_11210024_0 Hydroxymethylglutaryl-CoA lyase K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 467.0
CH2_k127_11210024_1 carboxylase K01968 - 6.4.1.4 0.0000000000000000000007638 98.0
CH2_k127_11219269_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 4.182e-225 713.0
CH2_k127_11219269_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 497.0
CH2_k127_11219269_2 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 465.0
CH2_k127_11219269_3 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 422.0
CH2_k127_11219269_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 337.0
CH2_k127_11219269_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007585 309.0
CH2_k127_11219269_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007841 291.0
CH2_k127_11219269_7 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001763 282.0
CH2_k127_11219269_8 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) - - - 0.00000000000000000000000000000000000000004755 156.0
CH2_k127_11219269_9 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000004853 128.0
CH2_k127_11224235_0 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000323 275.0
CH2_k127_11224235_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000003624 106.0
CH2_k127_11233636_0 cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001438 286.0
CH2_k127_11233636_1 excinuclease, ATPase subunit - - - 0.00000000000000000000000001284 109.0
CH2_k127_11233636_2 Acyltransferase family - - - 0.000000000000000000000004528 117.0
CH2_k127_11233636_3 Cysteine-rich secretory protein family K20276 - - 0.00001237 55.0
CH2_k127_11246732_0 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 433.0
CH2_k127_11246732_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000004237 221.0
CH2_k127_11249881_0 abc transporter atp-binding protein - - - 7.012e-314 966.0
CH2_k127_11249881_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.18e-217 681.0
CH2_k127_11249881_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005833 284.0
CH2_k127_11249881_3 hmm pf07719 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001176 263.0
CH2_k127_11249881_4 Glycosyl transferase K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000001819 231.0
CH2_k127_11249881_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000005804 223.0
CH2_k127_11249881_6 Glycosyltransferase like family - - - 0.0000000000000000000000000003436 124.0
CH2_k127_11249881_7 acetyltransferase - - - 0.00000000001049 68.0
CH2_k127_11289745_0 Multidrug MFS transporter - - - 3.574e-270 852.0
CH2_k127_11289745_1 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 425.0
CH2_k127_11289745_2 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase - - - 0.0000000000000000000000000000000000000000000000000001209 202.0
CH2_k127_11289745_3 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.000000000000000000000000000004968 119.0
CH2_k127_11312566_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000001367 210.0
CH2_k127_11312566_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000676 205.0
CH2_k127_11312566_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - - - 0.0000000000000002369 81.0
CH2_k127_11312566_3 - - - - 0.00000000252 61.0
CH2_k127_11320862_0 Belongs to the peptidase S8 family K14645 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 375.0
CH2_k127_11320862_1 Chaperone of endosialidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 375.0
CH2_k127_11320862_2 Tropinone reductase K08081 - 1.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 357.0
CH2_k127_11320862_3 Trypsin-like peptidase domain - - - 0.00000000000000000005936 102.0
CH2_k127_11320862_4 extracellular matrix structural constituent - - - 0.00000000000003929 85.0
CH2_k127_11320862_5 ASPIC and UnbV - - - 0.000000000002436 75.0
CH2_k127_11393971_0 Caspase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 456.0
CH2_k127_11455183_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.316e-284 878.0
CH2_k127_11455183_1 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009889,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2001141 - 0.0000001054 55.0
CH2_k127_11481942_0 AAA domain K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 595.0
CH2_k127_11481942_1 Predicted membrane protein (DUF2238) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000106 287.0
CH2_k127_11481942_2 Belongs to the UPF0149 family K07039 - - 0.000000000000000000000000000000000000000000000000000355 192.0
CH2_k127_11481942_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000009286 140.0
CH2_k127_11481942_4 Glyoxalase-like domain - - - 0.00000000000000000000000001302 111.0
CH2_k127_11484567_0 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 482.0
CH2_k127_11484567_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 456.0
CH2_k127_11484567_2 protease with the C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 411.0
CH2_k127_11484567_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 380.0
CH2_k127_11484567_4 FeS assembly SUF system protein SufT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 291.0
CH2_k127_11484567_5 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001298 252.0
CH2_k127_11484567_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03214 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003639 248.0
CH2_k127_11484567_7 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000005848 148.0
CH2_k127_11484567_8 Protein of unknown function (DUF533) - - - 0.0000000000000000000000000000001179 133.0
CH2_k127_11484567_9 aminopeptidase - - - 0.000000006705 57.0
CH2_k127_11502464_0 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 467.0
CH2_k127_11502464_1 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000006326 207.0
CH2_k127_11502464_2 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000009036 62.0
CH2_k127_11519518_0 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 GO:0000096,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0010309,GO:0016491,GO:0016701,GO:0016702,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0051213,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.13.11.53,1.13.11.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008585 274.0
CH2_k127_11519518_1 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0019509,GO:0019752,GO:0042578,GO:0043094,GO:0043102,GO:0043436,GO:0043874,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.77 0.00000000000000000000000000000000000000000000000000000000000000000000006334 246.0
CH2_k127_11519518_2 Peptidase C13 family - - - 0.00000000000000000000000000000000000000000000000000001208 208.0
CH2_k127_11553556_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 432.0
CH2_k127_11553556_1 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008791 264.0
CH2_k127_11553556_2 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.00002997 47.0
CH2_k127_11572338_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.00000000000000000000000000000000000000001993 168.0
CH2_k127_11572338_1 Cell Wall - - - 0.000000000001088 72.0
CH2_k127_11575276_0 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 525.0
CH2_k127_11575276_1 sensor diguanylate cyclase phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 442.0
CH2_k127_11575276_2 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 411.0
CH2_k127_11590799_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 586.0
CH2_k127_11590799_1 permease K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003203 286.0
CH2_k127_11590799_2 dna polymerase III K02339 - 2.7.7.7 0.00000000000000000000000000000000000000000000000001855 182.0
CH2_k127_11612205_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 559.0
CH2_k127_11612205_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 347.0
CH2_k127_11612205_2 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000006103 150.0
CH2_k127_11618727_0 Belongs to the AB hydrolase superfamily. MetX family K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 314.0
CH2_k127_11618727_1 cystathionine K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000003792 251.0
CH2_k127_11618727_2 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000002883 152.0
CH2_k127_11626169_0 chitin deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 553.0
CH2_k127_11626169_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 561.0
CH2_k127_11626169_2 OHCU decarboxylase K13485 - 4.1.1.97 0.00000000000000000000000000000000000000000001083 171.0
CH2_k127_11626182_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 290.0
CH2_k127_11626182_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005013 273.0
CH2_k127_11626182_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000001265 162.0
CH2_k127_11626182_4 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000000000000309 142.0
CH2_k127_11629096_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001307 301.0
CH2_k127_11629096_1 ECF sigma factor - - - 0.0000000000000002588 81.0
CH2_k127_11637689_0 7,8-dihydro-8-oxoguanine-triphosphatase K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 289.0
CH2_k127_11637689_1 Bacitracin ABC transporter ATP-binding protein K20459 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 295.0
CH2_k127_11637689_2 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000001822 198.0
CH2_k127_11637689_3 nucleotide binding property based on structural studies of Haemophilus influenzae crystallized protein in PDB Accession Number 1IN0 and NMR studies of Escherichia coli YajQ K09767 - - 0.0000000000000000000000000000000002846 142.0
CH2_k127_11637689_4 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000007792 107.0
CH2_k127_11637689_5 - - - - 0.00000000000000000000001606 117.0
CH2_k127_11637689_6 ABC-2 family transporter protein K20461 - - 0.000000001151 70.0
CH2_k127_11650109_0 due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 443.0
CH2_k127_11650109_1 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000766 100.0
CH2_k127_11650736_0 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 425.0
CH2_k127_11650736_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 359.0
CH2_k127_11670810_0 amine dehydrogenase activity - - - 1.217e-274 882.0
CH2_k127_11670810_1 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 461.0
CH2_k127_11670810_2 metallopeptidase activity - - - 0.000000000000000000000001852 121.0
CH2_k127_11670810_3 Ankyrin repeats (3 copies) - - - 0.000000000000002973 86.0
CH2_k127_11685162_0 membrane - - - 0.000000000000000000000000000000000000000000000008289 181.0
CH2_k127_11685162_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000001976 135.0
CH2_k127_11693177_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 501.0
CH2_k127_11693177_1 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000002517 215.0
CH2_k127_11693177_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000003891 197.0
CH2_k127_11693177_3 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000000001273 169.0
CH2_k127_11693177_4 PFAM glycosidase related protein - - - 0.00000000000000000002874 101.0
CH2_k127_11712750_0 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.0000000000000000000000000000000000000000000000000009065 202.0
CH2_k127_11723726_0 membrane K07148 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 415.0
CH2_k127_11728029_0 acyl-coa dehydrogenase - - - 1.693e-247 772.0
CH2_k127_11728029_1 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007446 256.0
CH2_k127_11728029_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000003461 134.0
CH2_k127_11729799_0 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002118 280.0
CH2_k127_11729799_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003532 270.0
CH2_k127_11729799_2 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002437 271.0
CH2_k127_11732664_0 periplasmic ligand-binding sensor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 348.0
CH2_k127_11732664_1 protein import K01179,K01406 - 3.2.1.4,3.4.24.40 0.000000000000411 79.0
CH2_k127_11751970_0 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 2.1e-198 626.0
CH2_k127_11751970_1 - - - - 0.0000000000000000000000000000000000000000000000609 171.0
CH2_k127_11768030_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 598.0
CH2_k127_11768030_1 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 466.0
CH2_k127_11768030_2 Acetylornithine deacetylase K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000004205 194.0
CH2_k127_11768368_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.151e-281 874.0
CH2_k127_11768368_1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07693 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 317.0
CH2_k127_11768368_2 Belongs to the UPF0176 family K07146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 322.0
CH2_k127_11768368_3 Domain of unknown function (DUF4190) - - - 0.0000000000000000000000005885 107.0
CH2_k127_11790851_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 390.0
CH2_k127_11790851_1 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 352.0
CH2_k127_11790851_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005648 307.0
CH2_k127_11790851_3 Domain of unknown function (DUF1287) K09974 - - 0.0000000000000000000000000000000000000000000000000000000000000000004265 233.0
CH2_k127_11790851_4 Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000005647 225.0
CH2_k127_11790851_5 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.000000000000000000000000000000002213 143.0
CH2_k127_11799095_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1173.0
CH2_k127_11799095_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 293.0
CH2_k127_11799095_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000001935 147.0
CH2_k127_11799095_4 peptidylprolyl isomerase K03770 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 5.2.1.8 0.000000000009369 70.0
CH2_k127_11810994_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 448.0
CH2_k127_11810994_1 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 300.0
CH2_k127_11810994_2 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001624 238.0
CH2_k127_11810994_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000002911 179.0
CH2_k127_11810994_4 YjbR - - - 0.00000000000000000000000004656 121.0
CH2_k127_11815685_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.249e-236 752.0
CH2_k127_11815685_1 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 524.0
CH2_k127_11823472_0 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000006348 223.0
CH2_k127_11823472_1 rna polymerase sigma factor - - - 0.000000000000000000000000000000000004556 142.0
CH2_k127_11854867_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 434.0
CH2_k127_11854867_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 387.0
CH2_k127_11854867_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 324.0
CH2_k127_11854867_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001088 259.0
CH2_k127_11854867_4 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000001108 238.0
CH2_k127_11854867_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000001813 167.0
CH2_k127_11854867_6 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000001007 156.0
CH2_k127_11854867_7 Acetyltransferase (GNAT) domain - - - 0.00000000000001448 84.0
CH2_k127_11855910_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 518.0
CH2_k127_11855910_1 Conserved repeat domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001233 249.0
CH2_k127_11879633_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 602.0
CH2_k127_11879633_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 476.0
CH2_k127_11879633_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000005656 93.0
CH2_k127_11879633_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000002759 83.0
CH2_k127_11879633_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000004748 73.0
CH2_k127_11896241_0 Male sterility protein K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 443.0
CH2_k127_11896241_1 capsular polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000001404 173.0
CH2_k127_11896241_2 SlyX K03745 - - 0.0000000003696 65.0
CH2_k127_11909745_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 3.593e-211 661.0
CH2_k127_11909745_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 496.0
CH2_k127_11909745_2 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 338.0
CH2_k127_11909745_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009296 278.0
CH2_k127_11909745_4 - - - - 0.000000000000000000000008591 111.0
CH2_k127_11909745_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000001949 58.0
CH2_k127_11912285_0 signal peptide peptidase K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 601.0
CH2_k127_11912285_1 Multidrug efflux pump K03327 GO:0003674,GO:0005215,GO:0006810,GO:0006855,GO:0008150,GO:0015238,GO:0015893,GO:0022857,GO:0042221,GO:0042493,GO:0042891,GO:0042895,GO:0046677,GO:0050896,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 391.0
CH2_k127_11912285_2 Protein of unknown function (DUF3667) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007993 287.0
CH2_k127_11912285_3 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000002868 203.0
CH2_k127_11912285_4 Rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000002966 162.0
CH2_k127_11912285_5 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000002069 147.0
CH2_k127_11912285_6 Domain of unknown function (DUF4156) - - - 0.00000000000000000000000003786 115.0
CH2_k127_11912868_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 586.0
CH2_k127_11912868_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000001046 132.0
CH2_k127_11978870_0 Belongs to the RimK family K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 439.0
CH2_k127_11978870_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 437.0
CH2_k127_11978870_10 Protein of unknown function (DUF433) - - - 0.00000000000000000000000005572 109.0
CH2_k127_11978870_11 - - - - 0.0000000000000000002697 92.0
CH2_k127_11978870_12 COG0457 FOG TPR repeat - - - 0.0000000000004107 80.0
CH2_k127_11978870_2 Di-haem cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 357.0
CH2_k127_11978870_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007581 282.0
CH2_k127_11978870_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003521 247.0
CH2_k127_11978870_5 glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000003051 231.0
CH2_k127_11978870_6 Inner membrane protein involved in colicin E2 resistance K06143 - - 0.00000000000000000000000000000000000000000000000000000000000002527 224.0
CH2_k127_11978870_7 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000004328 213.0
CH2_k127_11978870_8 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000003684 194.0
CH2_k127_11978870_9 Putative ATP-dependant zinc protease - - - 0.000000000000000000000000000000000000000000002152 172.0
CH2_k127_1199347_0 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 320.0
CH2_k127_1199347_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 289.0
CH2_k127_1199347_2 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000001388 223.0
CH2_k127_1199347_3 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.000000000000000000000000000000001776 137.0
CH2_k127_11996361_0 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000008891 245.0
CH2_k127_11996361_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000005732 230.0
CH2_k127_11996361_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000367 78.0
CH2_k127_1203488_0 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 507.0
CH2_k127_1203488_1 endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 325.0
CH2_k127_1203488_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008486 317.0
CH2_k127_1203488_3 - - - - 0.000000000000000000002514 104.0
CH2_k127_12035958_0 Cystathionine beta-synthase K01697 - 4.2.1.22 2.524e-250 779.0
CH2_k127_12035958_1 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000004151 190.0
CH2_k127_12078313_0 Autotransporter beta-domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 471.0
CH2_k127_12078313_1 Caspase domain - - - 0.0000000000000000000000000000000000000000000000000000000000139 214.0
CH2_k127_12101238_0 Transporter K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 392.0
CH2_k127_12101238_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002385 233.0
CH2_k127_12101238_2 hydrolase of the alpha beta superfamily - - - 0.00000000000000001036 91.0
CH2_k127_12103302_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002418 239.0
CH2_k127_12103302_1 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000002921 218.0
CH2_k127_12107388_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 453.0
CH2_k127_12107388_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 327.0
CH2_k127_12107388_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000214 138.0
CH2_k127_12132499_0 Domain of unknown function (DUF5117) - - - 4.809e-247 784.0
CH2_k127_12133398_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 1.539e-264 847.0
CH2_k127_12136559_0 2,4-dienoyl-coa reductase K00219 - 1.3.1.34 4.294e-210 662.0
CH2_k127_12163124_0 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 360.0
CH2_k127_12163124_1 Psort location Cytoplasmic, score 8.96 K02078 - - 0.0000000000000000000000000002264 117.0
CH2_k127_12163124_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000004455 115.0
CH2_k127_12163124_3 AMP-binding enzyme - - - 0.0000000000000000002149 98.0
CH2_k127_12163124_4 Beta-ketoacyl synthase, N-terminal domain - - - 0.000008327 50.0
CH2_k127_12166579_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 356.0
CH2_k127_12177300_0 MBOAT, membrane-bound O-acyltransferase family - - - 4.792e-237 739.0
CH2_k127_12177300_1 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000002361 228.0
CH2_k127_12177300_2 - - - - 0.000000000000000000004069 107.0
CH2_k127_12216145_0 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 331.0
CH2_k127_12216145_1 - - - - 0.00000000000000000000000000000000000000000003467 169.0
CH2_k127_12216145_2 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000007984 113.0
CH2_k127_12219934_0 Belongs to the WrbA family K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000009776 262.0
CH2_k127_12219934_1 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000002049 195.0
CH2_k127_12219934_2 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000002477 110.0
CH2_k127_12219934_3 membrane - - - 0.00000000001501 73.0
CH2_k127_12253409_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 500.0
CH2_k127_12253409_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 346.0
CH2_k127_12253409_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000909 130.0
CH2_k127_12260822_0 Bacterial transcriptional activator domain - - - 0.000003471 59.0
CH2_k127_12277687_0 CMP-binding protein K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002568 253.0
CH2_k127_12277687_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000807 121.0
CH2_k127_12296339_0 ErfK YbiS YcfS YnhG family protein K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 394.0
CH2_k127_12296339_1 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001163 276.0
CH2_k127_12296339_2 Predicted integral membrane protein (DUF2269) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000964 233.0
CH2_k127_12296339_3 Selenoprotein, putative - - - 0.00000000000000000001098 93.0
CH2_k127_12296339_4 Carbon starvation protein K06200 - - 0.000000004566 59.0
CH2_k127_12303227_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 334.0
CH2_k127_12303227_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008708 275.0
CH2_k127_12303227_2 Cytochrome c3 - - - 0.00000000000000000000004366 108.0
CH2_k127_12312063_0 receptor K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 320.0
CH2_k127_12315158_0 Peptidase family M1 domain - - - 2.088e-310 975.0
CH2_k127_12321796_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.67e-208 659.0
CH2_k127_12321796_1 Belongs to the glycosyl hydrolase family 6 K01081,K01179,K01183,K20276 - 3.1.3.5,3.2.1.14,3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007856 379.0
CH2_k127_1232304_0 Outer membrane efflux protein - - - 0.00000000000000000000006015 113.0
CH2_k127_1232304_1 Outer membrane efflux protein - - - 0.0000000000000000003095 93.0
CH2_k127_1232304_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000003669 55.0
CH2_k127_12330605_0 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001884 267.0
CH2_k127_12330605_1 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000005832 100.0
CH2_k127_12330605_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000001272 72.0
CH2_k127_12345361_0 ABC transporter K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 506.0
CH2_k127_12345361_1 AhpC/TSA family - - - 0.000000000000000428 80.0
CH2_k127_12354700_0 Type II secretion system (T2SS), protein E, N-terminal domain - - - 1.042e-235 741.0
CH2_k127_12354700_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000003432 235.0
CH2_k127_12354700_2 - - - - 0.0000000000000000000000003298 109.0
CH2_k127_12359924_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.572e-283 874.0
CH2_k127_12359924_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002449 273.0
CH2_k127_12359924_2 Major Facilitator Superfamily K03301 - - 0.0000000000000000000000000000000000000000000001227 176.0
CH2_k127_12359924_3 Domain of unknown function (DUF3391) - - - 0.00000000000000007291 82.0
CH2_k127_12360798_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 521.0
CH2_k127_12360798_1 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008433 306.0
CH2_k127_12360798_2 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000003277 105.0
CH2_k127_12368805_0 Belongs to the aldehyde dehydrogenase family K00146,K09472 - 1.2.1.39,1.2.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 582.0
CH2_k127_12368805_1 AAA domain - - - 0.00000000000000000000000000000001177 128.0
CH2_k127_12368805_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000004982 96.0
CH2_k127_12368805_3 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.000000000006914 69.0
CH2_k127_12411080_0 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 553.0
CH2_k127_12411080_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000001429 194.0
CH2_k127_12411080_2 Catalyzes the hydrolytic cleavage of a subset of L- isoaspartyl (L-beta-aspartyl) dipeptides. Used to degrade proteins damaged by L-isoaspartyl residues formation K01305 - - 0.0000000000000000000000000000000000000000007371 163.0
CH2_k127_12411080_3 Peptidase family M28 - - - 0.00000000000000000000000000000001522 145.0
CH2_k127_12423274_0 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 7.74e-212 665.0
CH2_k127_12423274_1 NADH ubiquinone oxidoreductase subunit K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 574.0
CH2_k127_12427369_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 488.0
CH2_k127_12427369_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000003729 199.0
CH2_k127_12427369_2 UPF0114 protein - - - 0.00000006948 54.0
CH2_k127_12448917_0 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 1.35e-232 730.0
CH2_k127_12448917_1 Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 584.0
CH2_k127_12448917_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 515.0
CH2_k127_12448917_3 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 495.0
CH2_k127_12448917_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 452.0
CH2_k127_12448917_5 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 397.0
CH2_k127_12448917_6 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 384.0
CH2_k127_12448917_7 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000000005061 166.0
CH2_k127_12461489_0 Protein tyrosine kinase K11912 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 346.0
CH2_k127_12461489_1 stringent starvation protein b K03600 - - 0.000000000000000000000000000000000000000000001394 172.0
CH2_k127_12461489_2 stringent starvation protein A K03599 - - 0.0000000000000000000000000000001203 124.0
CH2_k127_12461489_3 Protein of unknown function (DUF3301) - - - 0.0000000001507 66.0
CH2_k127_12469362_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 3.455e-202 634.0
CH2_k127_12514776_0 Sodium:sulfate symporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 566.0
CH2_k127_12514776_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 369.0
CH2_k127_12514776_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007774 263.0
CH2_k127_12514776_3 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003666 232.0
CH2_k127_12514776_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000004081 231.0
CH2_k127_12514776_5 antiporter K07301 - - 0.00000000000000000000000000000000000000000000000000000000000001043 227.0
CH2_k127_12514776_6 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000001986 226.0
CH2_k127_12514776_7 SMART Parallel beta-helix repeat - - - 0.00000005192 65.0
CH2_k127_12519791_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 7.682e-280 884.0
CH2_k127_12519791_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 441.0
CH2_k127_12519791_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 348.0
CH2_k127_12519791_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 321.0
CH2_k127_12519791_4 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 302.0
CH2_k127_12519791_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs - - - 0.00000000000000000000000000000000000000000000000000000008944 201.0
CH2_k127_12519791_6 Outer membrane protein (OmpH-like) - - - 0.00000000000000000001949 98.0
CH2_k127_12530936_0 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 514.0
CH2_k127_12530936_1 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 409.0
CH2_k127_12530936_2 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 354.0
CH2_k127_12530936_3 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 331.0
CH2_k127_12530936_4 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000994 297.0
CH2_k127_12530936_5 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001153 239.0
CH2_k127_12530936_6 YceI-like domain - - - 0.000000000000000000000000000000000000000000001214 170.0
CH2_k127_12530936_7 Protein of unknown function (DUF3999) - - - 0.00000000000000000000000000000000000984 151.0
CH2_k127_12530936_8 protein conserved in bacteria - - - 0.00000000000000000000005862 100.0
CH2_k127_1253488_0 Lytic murein transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 380.0
CH2_k127_1253488_1 membrane transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000001081 228.0
CH2_k127_12540814_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 1.641e-207 668.0
CH2_k127_12540814_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004163 256.0
CH2_k127_12543063_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 632.0
CH2_k127_12543063_1 Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates K01141 - 3.1.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 478.0
CH2_k127_12543063_2 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 316.0
CH2_k127_12543063_3 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000000000000000000000000000000000000000000000000000000001168 219.0
CH2_k127_12543063_4 Protein of unknown function (DUF998) - - - 0.000001025 56.0
CH2_k127_12561244_0 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 329.0
CH2_k127_12561244_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 300.0
CH2_k127_12561244_2 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000319 191.0
CH2_k127_12561244_3 membrane K08973 - - 0.000000000000000000000000000000000000000000001555 173.0
CH2_k127_12561244_4 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 - - 0.000000000000000003556 88.0
CH2_k127_1261804_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 443.0
CH2_k127_1261804_1 ATP ADP translocase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 318.0
CH2_k127_1261804_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000001637 103.0
CH2_k127_1261804_3 TIR domain - - - 0.0000000000000005575 92.0
CH2_k127_12629328_0 Sugar-transfer associated ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 544.0
CH2_k127_12629328_1 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 375.0
CH2_k127_12636642_0 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000139 275.0
CH2_k127_12636642_1 Helix-hairpin-helix domain K04477 - - 0.000000000000000000000000000000000000000007564 164.0
CH2_k127_12636642_2 alpha/beta hydrolase fold - - - 0.00000000000007416 81.0
CH2_k127_12653715_0 GGDEF domain - - - 2.401e-274 879.0
CH2_k127_12653715_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001024 279.0
CH2_k127_12653715_2 N-terminal region of glycosyl transferase group 7 - - - 0.0000000000000000000000000006976 121.0
CH2_k127_12676640_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 406.0
CH2_k127_12676640_1 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 321.0
CH2_k127_12676640_2 Dienelactone hydrolase family K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 297.0
CH2_k127_12676640_3 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000004191 224.0
CH2_k127_12676640_4 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000005365 168.0
CH2_k127_12695486_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 436.0
CH2_k127_12695486_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0015949,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001867 281.0
CH2_k127_12725873_0 domain, Protein - - - 0.0000000000000003587 82.0
CH2_k127_12725873_1 Domain of unknown function (DUF5122) beta-propeller - - - 0.00000000007932 74.0
CH2_k127_12736621_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 2.465e-299 939.0
CH2_k127_12737866_0 3-hydroxyacyl-coa dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 3.005e-278 870.0
CH2_k127_12737866_1 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 449.0
CH2_k127_12737866_2 - - - - 0.0000000000000000000001437 103.0
CH2_k127_12751937_0 Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present K03657 - 3.6.4.12 3.626e-310 964.0
CH2_k127_12751937_1 Tfp pilus assembly protein, major pilin PilA K02650 - - 0.0000000000000000000000000000001164 132.0
CH2_k127_12756812_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K00317 - 1.5.8.1,1.5.8.2 6.359e-251 787.0
CH2_k127_12756812_1 Domain of unknown function (DUF4331) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 576.0
CH2_k127_12769175_0 Potassium transporter TrkA - - - 1.883e-224 712.0
CH2_k127_12769175_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 451.0
CH2_k127_12769175_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 443.0
CH2_k127_12769175_3 Phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 305.0
CH2_k127_12769175_4 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 299.0
CH2_k127_12769175_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001213 257.0
CH2_k127_12769175_6 ferredoxin - - - 0.000000000000000000000002582 111.0
CH2_k127_12769175_7 Thiamine biosynthesis protein ThiS K03154 - - 0.0000000000000006793 83.0
CH2_k127_12769548_0 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 423.0
CH2_k127_12769548_1 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000002384 181.0
CH2_k127_12769548_2 Protein of unknown function (DUF3574) - - - 0.00000000000000000000000002976 114.0
CH2_k127_12775343_0 metallo-beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 441.0
CH2_k127_12775343_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 394.0
CH2_k127_12781910_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 299.0
CH2_k127_12781910_1 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000007205 182.0
CH2_k127_12781910_2 PFAM cytochrome c class II - - - 0.0000000000000006654 79.0
CH2_k127_12783619_0 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006790,GO:0008150,GO:0008152,GO:0009337,GO:0009987,GO:0016002,GO:0016491,GO:0016667,GO:0016673,GO:0019419,GO:0032991,GO:0044237,GO:0044424,GO:0044464,GO:0050311,GO:0055114 1.8.1.2 1.387e-282 877.0
CH2_k127_12783619_1 Belongs to the PAPS reductase family. CysH subfamily K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000108 177.0
CH2_k127_12783619_2 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component K00380 - 1.8.1.2 0.0000000000000000000000000008756 113.0
CH2_k127_12793512_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 545.0
CH2_k127_12793512_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 334.0
CH2_k127_12793512_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000106 194.0
CH2_k127_12793512_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000001262 172.0
CH2_k127_12793512_4 COG0784 FOG CheY-like receiver - - - 0.0000000000000000000274 104.0
CH2_k127_12793512_5 CYTH domain protein K01768 - 4.6.1.1 0.000000000007246 67.0
CH2_k127_12794394_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 405.0
CH2_k127_12794394_1 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K07400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003337 244.0
CH2_k127_12794394_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000009491 231.0
CH2_k127_12798015_0 Prolyl endopeptidase-like K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 505.0
CH2_k127_12811673_0 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 355.0
CH2_k127_12811673_1 SNF2 family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001202 265.0
CH2_k127_12811673_2 HipA-like C-terminal domain - - - 0.00000000000000000000000000000009571 129.0
CH2_k127_12831227_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 436.0
CH2_k127_12831227_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 296.0
CH2_k127_12835320_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000003163 260.0
CH2_k127_12835320_1 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000000000006834 216.0
CH2_k127_12850493_0 aconitate hydratase K20455 - 4.2.1.117 0.0 1237.0
CH2_k127_12850493_1 accessory protein K06959 - - 0.0 1084.0
CH2_k127_12850493_2 AcnD-accessory protein PrpF K09788 - - 4.083e-196 623.0
CH2_k127_12850493_3 ATPase associated with various cellular activities, AAA_5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 433.0
CH2_k127_12850493_4 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.0000000000000000000000000000000000001686 143.0
CH2_k127_12850493_5 PFAM plasmid maintenance system killer K07334 - - 0.000000000000000000000000000000003705 131.0
CH2_k127_12852782_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 409.0
CH2_k127_12852782_1 abc transporter atp-binding protein K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 393.0
CH2_k127_12852782_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 343.0
CH2_k127_12852782_3 7TMR-DISM extracellular 2 - - - 0.0004827 43.0
CH2_k127_12857338_0 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 435.0
CH2_k127_12857338_1 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000000000000000001368 163.0
CH2_k127_12857338_2 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.00000000000000000000000000000000008925 139.0
CH2_k127_12857338_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000009658 61.0
CH2_k127_12868914_0 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 505.0
CH2_k127_12868914_1 - - - - 0.0006524 42.0
CH2_k127_12910862_0 Phosphate starvation protein PhoH K07175 - - 4.498e-236 738.0
CH2_k127_12910862_1 Glycine cleavage system regulatory protein K03567 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004733 248.0
CH2_k127_12910862_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.00006204 50.0
CH2_k127_12928814_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 526.0
CH2_k127_12928814_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 368.0
CH2_k127_1293747_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1406.0
CH2_k127_1293747_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 459.0
CH2_k127_1293747_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 399.0
CH2_k127_1293747_3 phosphorelay sensor kinase activity K21020 - 2.7.7.65 0.0000000000000000000000000000000000000000001593 173.0
CH2_k127_1293747_4 Acetyltransferase K06975 - - 0.000000000000005006 78.0
CH2_k127_12951083_0 decarboxylase - - - 1.175e-311 970.0
CH2_k127_12951083_1 protein involved in response to NO K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 501.0
CH2_k127_12951083_2 cysteine synthase K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000009283 234.0
CH2_k127_12951083_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000003245 211.0
CH2_k127_12951083_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000000000000000003078 166.0
CH2_k127_13000369_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 6.761e-233 732.0
CH2_k127_13000369_1 Helicase K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000001597 190.0
CH2_k127_13018125_0 diguanylate cyclase - - - 8.014e-229 742.0
CH2_k127_13018125_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 374.0
CH2_k127_13018125_2 Peptidoglycan-synthase activator LpoB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 316.0
CH2_k127_13018125_3 Pregnancy-associated plasma protein-A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008038 269.0
CH2_k127_13018125_4 In Escherichia coli the protein UvrY is part of a two-component system along with BarA that is needed for efficient switching between glycolytic and gluconeogenic carbon sources possibly by regulating the Csr system - - - 0.00000000000000000000000000000000000000000000000000000000000001841 221.0
CH2_k127_13040542_0 Catalyzes the reversible formation of glyoxylate and succinate from isocitrate K01637 - 4.1.3.1 3.289e-226 706.0
CH2_k127_13040542_1 Catalyzes the aldol condensation of glyoxylate with acetyl-CoA to form malate as part of the second step of the glyoxylate bypass and an alternative to the tricarboxylic acid cycle K01638 - 2.3.3.9 1.118e-221 700.0
CH2_k127_13040542_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000001089 160.0
CH2_k127_13064816_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 523.0
CH2_k127_13064816_1 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000000000000000001803 196.0
CH2_k127_13064816_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000002725 149.0
CH2_k127_131109_0 Cell division protein ftsk K03466 - - 2.185e-226 716.0
CH2_k127_131109_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008561 537.0
CH2_k127_131109_2 protein conserved in bacteria K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 389.0
CH2_k127_131109_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000001131 224.0
CH2_k127_1319555_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 5.593e-258 801.0
CH2_k127_1319555_1 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000004145 182.0
CH2_k127_1319555_2 Transcriptional regulator K07726 - - 0.00000000000000000000000001044 113.0
CH2_k127_1319555_3 Lamin Tail Domain - - - 0.0000000000000002463 87.0
CH2_k127_1319555_4 RDD family - - - 0.0000000001199 73.0
CH2_k127_1342821_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 0.0 1103.0
CH2_k127_1342821_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 376.0
CH2_k127_1342821_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003917 270.0
CH2_k127_1355809_0 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 2.857e-206 648.0
CH2_k127_1355809_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000002926 242.0
CH2_k127_1355809_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000001062 208.0
CH2_k127_1355809_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000001926 204.0
CH2_k127_1355809_4 rubredoxin - - - 0.000000000000000000000000001677 111.0
CH2_k127_1393026_0 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 404.0
CH2_k127_1393026_1 protein conserved in bacteria K09920 - - 0.00000000000000000000000000000003388 128.0
CH2_k127_1402596_0 FAD-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 554.0
CH2_k127_1402596_1 Histidine Phosphotransfer domain K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 372.0
CH2_k127_1406120_0 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 638.0
CH2_k127_1406120_1 IMG reference gene - - - 0.000000000000000000000000000000000000000000000000000000000000006548 249.0
CH2_k127_1406621_0 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 529.0
CH2_k127_1406621_1 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000441 282.0
CH2_k127_1406621_2 KR domain K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000002816 212.0
CH2_k127_1422670_0 Transporter K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 357.0
CH2_k127_1422670_1 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000004331 216.0
CH2_k127_1422670_2 enzyme of the cupin superfamily K06995 - - 0.00000000000000000000000000000000000001651 147.0
CH2_k127_1422670_3 Domain of unknown function (DUF4440) - - - 0.0005438 51.0
CH2_k127_1433811_0 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 364.0
CH2_k127_1433811_1 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001705 249.0
CH2_k127_1433811_2 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000001235 149.0
CH2_k127_1433811_3 - - - - 0.00026 50.0
CH2_k127_1443320_0 Belongs to the flagella basal body rod proteins family K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 392.0
CH2_k127_1443320_1 basal body rod protein K02391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 339.0
CH2_k127_1443320_2 Flagellar hook protein flgE K02390 - - 0.000000000000000000000000000000000000000000000000001052 184.0
CH2_k127_1477305_0 Y_Y_Y domain K10125 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 495.0
CH2_k127_1477305_1 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000001236 229.0
CH2_k127_1477305_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000135 73.0
CH2_k127_1548546_0 ATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease K03694 - - 4.666e-215 673.0
CH2_k127_1548546_1 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000002954 78.0
CH2_k127_1551818_0 PAS fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 576.0
CH2_k127_1551818_1 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 374.0
CH2_k127_1551818_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000001188 207.0
CH2_k127_1551818_3 Bacterial PH domain K08981 - - 0.000000000000000000000000000000000000000000000000004222 190.0
CH2_k127_1551818_4 - - - - 0.0000000000000000002625 98.0
CH2_k127_1551818_5 Acyl carrier protein phosphodiesterase - - - 0.0000000000000982 72.0
CH2_k127_1551818_6 - - - - 0.0008502 50.0
CH2_k127_1565994_0 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 357.0
CH2_k127_1565994_1 - - - - 0.00000000000000000003905 99.0
CH2_k127_1565994_2 - - - - 0.000000000000000003202 91.0
CH2_k127_156803_0 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 339.0
CH2_k127_1582900_0 Fatty acid desaturase K00496 - 1.14.15.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 525.0
CH2_k127_1582900_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 505.0
CH2_k127_1582900_2 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009389 278.0
CH2_k127_1582900_3 Competence protein - - - 0.0000000000000000000000000000000000000000000000000000000000005597 218.0
CH2_k127_1582900_4 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000002188 151.0
CH2_k127_1582900_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000001618 112.0
CH2_k127_1596003_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000002295 168.0
CH2_k127_1596003_1 diguanylate cyclase - - - 0.0000000000000000000000000000000001459 147.0
CH2_k127_1612092_0 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 338.0
CH2_k127_1612092_1 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000000000000001058 165.0
CH2_k127_1612092_2 Histidine kinase - - - 0.00000000000000000000000000000000000002356 152.0
CH2_k127_1613276_0 Cadherin repeats. - - - 0.000000000000000000000000000000000184 154.0
CH2_k127_1666640_0 General secretion pathway protein K02453 - - 3.883e-199 646.0
CH2_k127_1666640_1 Type II secretion system protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001984 285.0
CH2_k127_1666640_2 General secretion pathway protein K02461 - - 0.000000000000000000000000000000000000000000000000000000000000001418 235.0
CH2_k127_1666640_3 General secretion pathway protein K02459 - - 0.00000000000000000000000000000000000000000001679 173.0
CH2_k127_1666640_4 General secretion pathway protein K02462 - - 0.00000000000000000000000000000000001301 143.0
CH2_k127_1666640_5 General secretion pathway protein K02458 - - 0.000000000000000000000000000416 119.0
CH2_k127_1666640_6 COG4970 Tfp pilus assembly protein FimT K02457 - - 0.00000000000000000000000006967 109.0
CH2_k127_1666640_7 General secretion pathway protein K02463 - - 0.00000000000002183 82.0
CH2_k127_1667274_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1458.0
CH2_k127_1667274_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 358.0
CH2_k127_1667274_2 AAA domain K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000006072 238.0
CH2_k127_1667274_3 membrane protein (homolog of Drosophila rhomboid) - - - 0.000000000000000000000000000000000000000000000000001382 193.0
CH2_k127_1667274_4 Type II secretion system protein B - - - 0.0000000000000000005801 99.0
CH2_k127_1691803_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.599e-231 724.0
CH2_k127_1691803_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 531.0
CH2_k127_1691803_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 418.0
CH2_k127_1691803_3 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 368.0
CH2_k127_1691803_4 component I K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 362.0
CH2_k127_1691803_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000002364 144.0
CH2_k127_1698598_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001038 289.0
CH2_k127_1698598_1 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000793 222.0
CH2_k127_1733260_0 abc transporter, permease K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 524.0
CH2_k127_1733260_1 abc transporter atp-binding protein K02065 - - 0.000000000000000000000000000003674 121.0
CH2_k127_1734611_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 452.0
CH2_k127_1734611_1 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 295.0
CH2_k127_1734611_2 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000001036 75.0
CH2_k127_1734611_3 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000001186 53.0
CH2_k127_1743486_0 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 498.0
CH2_k127_1743486_1 ferredoxin--nadp reductase K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 431.0
CH2_k127_1743486_2 phenazine biosynthesis protein PhzF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 376.0
CH2_k127_1743486_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000001613 223.0
CH2_k127_1743486_5 acetyl-coa hydrolase - - - 0.0000000000000009024 81.0
CH2_k127_1753965_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 533.0
CH2_k127_1753965_1 - - - - 0.0000000000000000000000000000000000000000000000007435 188.0
CH2_k127_1753965_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000001702 139.0
CH2_k127_1753965_3 membrane protein involved in D-alanine export - - - 0.000000000000001083 82.0
CH2_k127_1759667_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 583.0
CH2_k127_1768865_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.333e-228 720.0
CH2_k127_1781715_0 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 463.0
CH2_k127_1781715_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 369.0
CH2_k127_1781715_2 abc transporter atp-binding protein K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 346.0
CH2_k127_1781715_3 the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001365 273.0
CH2_k127_1781715_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000001098 234.0
CH2_k127_1781715_5 Pilus assembly protein PilZ K02676 - - 0.000000000000000000000000000000000000000000000000004382 185.0
CH2_k127_1781715_6 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000001788 184.0
CH2_k127_1781715_7 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.000000000000000000000002556 110.0
CH2_k127_1781715_8 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.0000000000000000002568 95.0
CH2_k127_1781715_9 Catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate K02619 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 4.1.3.38 0.000000000000002941 84.0
CH2_k127_1787645_0 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 330.0
CH2_k127_1787645_1 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000005684 204.0
CH2_k127_1787645_2 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000001375 204.0
CH2_k127_1787645_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000003489 188.0
CH2_k127_1787645_4 SET domain K07117 - - 0.00000000000000000000000000000000000000005113 158.0
CH2_k127_1787645_5 Acyltransferase family - - - 0.0000000000000000001826 93.0
CH2_k127_1787645_6 PFAM Outer membrane lipoprotein Slp K07285 - - 0.00000000000000003499 93.0
CH2_k127_1838582_0 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 299.0
CH2_k127_1838582_1 - - - - 0.000004126 54.0
CH2_k127_184942_0 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002261 244.0
CH2_k127_184942_1 Tetratricopeptide repeat K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000004419 261.0
CH2_k127_1851934_0 Metalloenzyme superfamily K01839 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008973,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008627 425.0
CH2_k127_1851934_1 Phosphorylase superfamily K03784 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000203 284.0
CH2_k127_1851934_2 penicillin-binding protein K05367 - 2.4.1.129 0.00000001164 57.0
CH2_k127_1882117_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 566.0
CH2_k127_1882117_1 3HB-oligomer hydrolase (3HBOH) K07518 - 3.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 528.0
CH2_k127_1882117_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.00000000000000000000000000000000000000001512 156.0
CH2_k127_1902227_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 3.504e-225 736.0
CH2_k127_1906273_0 membrane K03760 - 2.7.8.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 593.0
CH2_k127_1906273_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000001031 155.0
CH2_k127_191581_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000001186 162.0
CH2_k127_1933373_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007131 480.0
CH2_k127_1933373_1 Phosphotransferase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 383.0
CH2_k127_1933373_2 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 302.0
CH2_k127_1933373_3 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000001131 273.0
CH2_k127_1933373_4 - - - - 0.0000000000000000000000000000000000005856 149.0
CH2_k127_1933373_5 M6 family metalloprotease domain protein - - - 0.00000000000000001124 89.0
CH2_k127_1938095_0 Hep Hag repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002468 268.0
CH2_k127_1967025_0 dihydroorotate dehydrogenase family K17723,K17828 - 1.3.1.1,1.3.1.14 6.601e-245 759.0
CH2_k127_1967025_1 Permease for cytosine/purines, uracil, thiamine, allantoin - - - 1.696e-210 662.0
CH2_k127_1967025_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17722 - 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 524.0
CH2_k127_1967025_3 guanyl-nucleotide exchange factor activity K20276 - - 0.000000000000000000000000000000000000000494 170.0
CH2_k127_1967025_4 guanyl-nucleotide exchange factor activity K20276 - - 0.00000003103 64.0
CH2_k127_1973657_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 472.0
CH2_k127_1973657_1 due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 429.0
CH2_k127_1973657_2 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 347.0
CH2_k127_2015303_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 496.0
CH2_k127_2015303_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 400.0
CH2_k127_2015303_2 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000001171 192.0
CH2_k127_2015303_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000001901 178.0
CH2_k127_2016253_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 497.0
CH2_k127_2016253_1 SMART helix-turn-helix domain protein K18831 - - 0.000000000000000000000000000000000001762 145.0
CH2_k127_2016253_2 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.000000000000000000000000000008331 121.0
CH2_k127_2016253_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000004636 112.0
CH2_k127_2016253_4 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000757 89.0
CH2_k127_2016253_5 Amidohydrolase family - - - 0.0000000000001161 76.0
CH2_k127_2016253_6 - - - - 0.00000000001411 68.0
CH2_k127_2021324_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.009e-308 972.0
CH2_k127_2021324_1 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 344.0
CH2_k127_2021324_2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000007126 154.0
CH2_k127_203059_0 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 0.0 1141.0
CH2_k127_203059_1 multicopper - - - 2.069e-234 732.0
CH2_k127_203059_2 protease with the C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 321.0
CH2_k127_203059_3 Domain of unknown function (DUF305) - - - 0.00000000000000003223 91.0
CH2_k127_2038147_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000001008 154.0
CH2_k127_2038147_1 PDZ domain - - - 0.00000000000000000000000000000001371 134.0
CH2_k127_2047330_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 344.0
CH2_k127_2047330_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000005371 180.0
CH2_k127_2051166_0 COG0618 Exopolyphosphatase-related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 409.0
CH2_k127_2051166_1 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 332.0
CH2_k127_2051166_2 SMR domain protein - - - 0.000000000000000000000000000000000000000000000251 173.0
CH2_k127_2051166_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000002412 151.0
CH2_k127_2091814_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000321 252.0
CH2_k127_2091814_1 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000001269 85.0
CH2_k127_2104878_0 membrane K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 385.0
CH2_k127_2104878_1 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000009333 250.0
CH2_k127_2104878_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001471 256.0
CH2_k127_2104878_3 Pathogenicity protein K09800 - - 0.0000000000000000000000000000000000003689 162.0
CH2_k127_2130206_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 427.0
CH2_k127_2130206_1 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005495 244.0
CH2_k127_2130206_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000479 185.0
CH2_k127_2130206_3 PFAM molybdopterin biosynthesis MoaE protein K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000008407 160.0
CH2_k127_2130206_4 trab family - - - 0.0000000000000000000000000176 110.0
CH2_k127_2130206_5 Molybdopterin K03636 - - 0.000000000000000000001156 96.0
CH2_k127_2136485_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138,K18303,K21134 - - 0.0 1377.0
CH2_k127_2136485_1 abc transporter atp-binding protein K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 379.0
CH2_k127_2136485_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18302 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 324.0
CH2_k127_2136485_3 abc transporter, permease K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 284.0
CH2_k127_2136485_4 transcriptional regulator K18301 - - 0.00000000000000000000000000000000000000000000000000000000000003457 221.0
CH2_k127_2136485_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000002348 149.0
CH2_k127_2136485_6 ECF sigma factor - - - 0.00000000000000000000000000000000002843 141.0
CH2_k127_215302_0 COG3209 Rhs family protein - - - 0.000000000000000000000000000002103 132.0
CH2_k127_215302_1 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000003732 112.0
CH2_k127_2161222_0 Pyrimidine nucleoside phosphorylase C-terminal domain K00758 - 2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 404.0
CH2_k127_2161222_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000001933 83.0
CH2_k127_2165021_0 abc transporter atp-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 411.0
CH2_k127_2165021_1 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000005634 234.0
CH2_k127_2165021_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000003563 132.0
CH2_k127_2224766_0 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 522.0
CH2_k127_2224766_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000003236 69.0
CH2_k127_2237073_0 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 1.36e-199 631.0
CH2_k127_2237073_1 Peptidase M16 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 536.0
CH2_k127_2239409_0 Cardiolipin synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001445 248.0
CH2_k127_2239409_1 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000000000000000000000003087 220.0
CH2_k127_2260073_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 4.623e-219 686.0
CH2_k127_2260073_1 4-hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 5.261e-205 641.0
CH2_k127_2260073_2 2-keto-4-pentenoate hydratase K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 552.0
CH2_k127_2260073_3 twitching motility protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 511.0
CH2_k127_2260073_4 maleylacetoacetate isomerase K01800 - 5.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 302.0
CH2_k127_2274499_0 virion core protein (lumpy skin disease virus) - - - 2.351e-219 685.0
CH2_k127_2274499_1 bacterial-type flagellum-dependent swarming motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000003411 234.0
CH2_k127_2299650_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 344.0
CH2_k127_2299650_1 Hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 259.0
CH2_k127_2299650_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000002859 51.0
CH2_k127_230389_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 499.0
CH2_k127_230389_1 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008578 494.0
CH2_k127_230389_2 COG2951 Membrane-bound lytic murein transglycosylase B K08305 - - 0.0000004377 55.0
CH2_k127_2336141_0 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 503.0
CH2_k127_2336141_1 Branched-chain amino acid aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 363.0
CH2_k127_2336141_2 Family of unknown function (DUF695) - - - 0.00000000000000000000000000000006337 128.0
CH2_k127_2336141_3 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K01782,K01825 GO:0003674,GO:0003824,GO:0003857,GO:0004165,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0008692,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0016856,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.00000111 51.0
CH2_k127_2345844_0 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 414.0
CH2_k127_2345844_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 396.0
CH2_k127_2345844_2 Response regulator of the LytR AlgR family K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002329 283.0
CH2_k127_2345844_3 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003356 276.0
CH2_k127_2345844_4 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001135 273.0
CH2_k127_2345844_5 salt-induced outer membrane protein K07283 - - 0.0000000000000000000000000000000000000000000000000000000000000298 224.0
CH2_k127_2349328_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1378.0
CH2_k127_2349328_1 thioesterase K07107 - - 0.0000000000000000000000000000000000003087 148.0
CH2_k127_2349328_2 Zinc metalloprotease (Elastase) K01183 - 3.2.1.14 0.0000000000000000000000404 106.0
CH2_k127_2366198_0 PFAM Phospholipase D Transphosphatidylase K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007645 274.0
CH2_k127_2366198_1 PFAM glycosidase, PH1107-related K20885 - 2.4.1.339,2.4.1.340 0.000000000000000000000000000000000000000000000000000000000000000000000002 267.0
CH2_k127_2366198_2 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000003116 206.0
CH2_k127_2367551_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 474.0
CH2_k127_2367551_1 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 436.0
CH2_k127_2367551_2 GGDEF domain - - - 0.0000000000000000001534 94.0
CH2_k127_2367551_3 pectin acetylesterase activity K14574,K19882 - 3.1.1.98 0.0006751 52.0
CH2_k127_2371700_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 511.0
CH2_k127_2371700_1 Belongs to the inositol monophosphatase superfamily K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 318.0
CH2_k127_2371700_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004339 273.0
CH2_k127_2371700_3 Hemolysins and related proteins containing CBS domains K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000001721 238.0
CH2_k127_2371700_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000002713 226.0
CH2_k127_2371700_5 BolA family transcriptional regulator K09780 - - 0.000000000000000000000000000000000000000002387 156.0
CH2_k127_2371700_6 exopolysaccharide synthesis - - - 0.0000000000000000000000000000000005208 139.0
CH2_k127_2371700_7 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000000002343 113.0
CH2_k127_2375113_0 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 302.0
CH2_k127_2375113_1 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000007224 240.0
CH2_k127_2375113_2 Inositol monophosphatase family K05602 - 3.1.3.15 0.0000000000000000000000000000000000000000005865 160.0
CH2_k127_2382711_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 2.901e-320 996.0
CH2_k127_2382711_1 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 304.0
CH2_k127_2410216_0 Outer membrane receptor - - - 6.93e-248 797.0
CH2_k127_2410216_1 Belongs to the Orn Lys Arg decarboxylase class-II family K12526 - 2.7.2.4,4.1.1.20 1.64e-201 644.0
CH2_k127_2410216_2 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000009018 61.0
CH2_k127_2410216_3 Type IV pilus biogenesis stability protein PilW - - - 0.0007853 51.0
CH2_k127_2419618_0 GatB domain - - - 2.794e-203 644.0
CH2_k127_2419618_1 Sugar kinase K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 581.0
CH2_k127_2419618_2 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 527.0
CH2_k127_243025_0 alpha/beta hydrolase fold K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 556.0
CH2_k127_243025_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 472.0
CH2_k127_243025_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 355.0
CH2_k127_243025_3 MFS transporter K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 340.0
CH2_k127_243025_4 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006814 263.0
CH2_k127_243025_5 Poly(R)-hydroxyalkanoic acid synthase subunit - - - 0.0000000000000000000000000000000000000000000000000007953 197.0
CH2_k127_2437648_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 1.012e-309 957.0
CH2_k127_2452869_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 489.0
CH2_k127_2452869_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 289.0
CH2_k127_2452869_2 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.00000000000000000000000000000000000000001075 159.0
CH2_k127_2466863_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 580.0
CH2_k127_2466863_1 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 323.0
CH2_k127_2466863_2 Two component regulator propeller K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000008826 207.0
CH2_k127_2466863_3 Nuclease-like protein - - - 0.0006978 50.0
CH2_k127_2468592_0 Zinc metalloprotease (Elastase) K01399,K08604 - 3.4.24.25,3.4.24.26 2.734e-319 994.0
CH2_k127_2468592_1 Calx-beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000001645 241.0
CH2_k127_2468592_2 Zinc metalloprotease (Elastase) K01399,K08604 - 3.4.24.25,3.4.24.26 0.000000000000000000000000000000000000001129 171.0
CH2_k127_2480375_0 aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 306.0
CH2_k127_2480375_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009271 272.0
CH2_k127_2480375_2 - - - - 0.00000000000000000000000000000000000000000000000005784 188.0
CH2_k127_2503411_0 Putative diguanylate phosphodiesterase - - - 2.284e-204 661.0
CH2_k127_2503411_1 PFAM Tetratricopeptide - - - 0.000000000000000000000004322 108.0
CH2_k127_255223_0 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000393 207.0
CH2_k127_255223_1 Helicase K03578 - 3.6.4.13 0.000000000000000000000000000000000002394 143.0
CH2_k127_255223_2 - - - - 0.0000000000000000000000000001281 121.0
CH2_k127_255223_3 Methyltransferase domain - - - 0.00004768 52.0
CH2_k127_2566019_0 Diguanylate cyclase - - - 4.44e-207 671.0
CH2_k127_2569227_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 7.121e-265 820.0
CH2_k127_2569227_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.076e-251 784.0
CH2_k127_2569227_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009546 340.0
CH2_k127_2569227_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 332.0
CH2_k127_2569227_4 NADH dehydrogenase K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 307.0
CH2_k127_2569227_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001017 185.0
CH2_k127_2569227_6 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.000000000000000000000000000004748 121.0
CH2_k127_2569227_7 Preprotein translocase subunit SecG K03075 - - 0.0000000000000000000000000006685 119.0
CH2_k127_2576875_0 oxidoreductase K06940 - - 0.0000000000000000000000000000000000000000000000000000000002807 204.0
CH2_k127_2576875_1 Histone deacetylase domain - - - 0.0000000000000000000000001001 111.0
CH2_k127_2576875_2 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000253 94.0
CH2_k127_25881_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 382.0
CH2_k127_25881_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 304.0
CH2_k127_25881_10 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000115 82.0
CH2_k127_25881_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006675 254.0
CH2_k127_25881_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000003505 233.0
CH2_k127_25881_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001801 228.0
CH2_k127_25881_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003528 190.0
CH2_k127_25881_6 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000004042 171.0
CH2_k127_25881_7 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000007324 158.0
CH2_k127_25881_8 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001903 153.0
CH2_k127_25881_9 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000001541 125.0
CH2_k127_2631028_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000846 332.0
CH2_k127_2631028_1 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001836 253.0
CH2_k127_2631028_2 Ethylbenzene dehydrogenase - - - 0.00000000000000000003906 91.0
CH2_k127_2635358_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.887e-233 735.0
CH2_k127_2635358_1 Mechanosensitive ion channel K05802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 540.0
CH2_k127_2635358_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 365.0
CH2_k127_2635358_3 Glutamyl-tRNA amidotransferase K09117 - - 0.000000000000000000000000000000000000000000000000000000000002154 215.0
CH2_k127_2635358_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000003898 173.0
CH2_k127_2635358_5 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000001356 128.0
CH2_k127_264399_0 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 402.0
CH2_k127_264399_1 electron transfer flavoprotein beta subunit K03521 - - 0.00000000000000000000000000000000000000000000000002846 179.0
CH2_k127_2659788_0 guanyl-nucleotide exchange factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 515.0
CH2_k127_2659788_1 endonuclease containing a URI domain K07461 - - 0.000000000000000000000000000003674 121.0
CH2_k127_2672897_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 9.703e-287 887.0
CH2_k127_2672897_1 PFAM cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 334.0
CH2_k127_2672897_2 Cytochrome oxidase assembly protein K02259 - - 0.0000000000000000000000000000000000000000000000001513 189.0
CH2_k127_2672897_3 - - - - 0.0000000000000006654 79.0
CH2_k127_2686771_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 5.383e-206 646.0
CH2_k127_2686771_1 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 289.0
CH2_k127_2686771_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001414 239.0
CH2_k127_2704417_0 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007664 361.0
CH2_k127_2704417_1 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000006501 115.0
CH2_k127_2713992_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000008225 250.0
CH2_k127_2713992_1 Transcriptional regulator - - - 0.00000000000000000000000003108 119.0
CH2_k127_2716595_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 3.183e-215 677.0
CH2_k127_2716595_1 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000002734 203.0
CH2_k127_2716595_2 glycosyl - - - 0.000000000000000000000000000000000000000001581 170.0
CH2_k127_2716595_3 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000002352 117.0
CH2_k127_2729392_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 412.0
CH2_k127_2729392_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K19696 - 2.4.2.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000413 263.0
CH2_k127_2729392_2 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000009749 206.0
CH2_k127_2729392_3 CYTH domain protein K01768 - 4.6.1.1 0.0000000000000000000000000000007974 124.0
CH2_k127_2744745_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.688e-233 727.0
CH2_k127_2744745_1 Belongs to the IUNH family K01239 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 362.0
CH2_k127_2744745_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001217 265.0
CH2_k127_2744745_3 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000000000000000008006 205.0
CH2_k127_2744745_4 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000002616 189.0
CH2_k127_2744745_5 Ribosomal protein L31 K02909 - - 0.00000000000000000000000000000000000006601 143.0
CH2_k127_2762593_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 330.0
CH2_k127_2762593_1 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.00000000000000000000000000000000000000000000000000000000000000000000000005841 252.0
CH2_k127_2762593_2 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000001422 219.0
CH2_k127_2762593_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000005406 206.0
CH2_k127_2762593_4 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000007496 172.0
CH2_k127_2788880_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 369.0
CH2_k127_2789005_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 324.0
CH2_k127_2789005_1 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 306.0
CH2_k127_2789005_10 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000004251 61.0
CH2_k127_2789005_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000122 252.0
CH2_k127_2789005_3 Peroxiredoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000006772 242.0
CH2_k127_2789005_4 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000004732 220.0
CH2_k127_2789005_5 Protein chain release factor B K15034 - - 0.000000000000000000000000000000000000000000000000009426 183.0
CH2_k127_2789005_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000007561 89.0
CH2_k127_2789005_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000009428 78.0
CH2_k127_2789005_8 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000002502 78.0
CH2_k127_2789005_9 - - - - 0.000000002667 67.0
CH2_k127_2789399_0 LuxR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004138 273.0
CH2_k127_2789399_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000001157 223.0
CH2_k127_2789399_2 determination of stomach left/right asymmetry - - - 0.00000000000000000000000003158 122.0
CH2_k127_2845508_0 COG1071 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 466.0
CH2_k127_2845508_1 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 464.0
CH2_k127_2845508_2 Protein of unknown function (DUF3616) K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001331 278.0
CH2_k127_2845508_3 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000008733 186.0
CH2_k127_2845508_4 oxidoreductase activity - - - 0.00000000000000000000000000000000000000003632 175.0
CH2_k127_2848553_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 338.0
CH2_k127_2848553_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 300.0
CH2_k127_2848553_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002293 248.0
CH2_k127_2866942_0 Splits dipeptides with a prolyl residue in the C- terminal position K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 518.0
CH2_k127_2866942_1 aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 327.0
CH2_k127_2866942_2 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000000000000000000000000000001771 183.0
CH2_k127_2866942_3 Plasmid maintenance system killer K07334 - - 0.0000000000000000000000000000000000000000001203 163.0
CH2_k127_2866942_4 PilZ domain - - - 0.0000000000000000000000001146 109.0
CH2_k127_2882743_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.842e-300 930.0
CH2_k127_2882743_1 COG1555 DNA uptake protein and related DNA-binding proteins K02237 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.000000000000000001244 88.0
CH2_k127_2882743_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00003149 46.0
CH2_k127_2884701_0 Putative sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 357.0
CH2_k127_2884701_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 313.0
CH2_k127_2884701_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000002096 220.0
CH2_k127_2884701_3 Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000001262 200.0
CH2_k127_2884701_4 PadR family transcriptional regulator K10947 - - 0.000000000000000000000000000000000000000000003279 168.0
CH2_k127_2910792_0 Acyl transferase domain - - - 2.039e-244 769.0
CH2_k127_2910792_1 2-Nitropropane dioxygenase - - - 0.00000000000000000000000000000000000000000000000023 177.0
CH2_k127_2921620_0 Oar protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 346.0
CH2_k127_2921620_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000005069 78.0
CH2_k127_2928340_0 Molecular chaperone. Has ATPase activity K04079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 524.0
CH2_k127_2928340_1 Domain of unknown function (DUF4139) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 473.0
CH2_k127_2928340_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 451.0
CH2_k127_2928340_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000002701 67.0
CH2_k127_2931749_0 Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1794.0
CH2_k127_2931749_1 Single-stranded-DNA-specific exonuclease K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 395.0
CH2_k127_2931749_2 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 291.0
CH2_k127_2931749_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000002315 215.0
CH2_k127_2931749_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000005253 193.0
CH2_k127_2932746_0 Catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 1.067e-224 713.0
CH2_k127_2932746_1 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 366.0
CH2_k127_2932746_2 thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 353.0
CH2_k127_2932746_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 320.0
CH2_k127_2932746_4 PFAM Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000001467 242.0
CH2_k127_2932746_5 Cell division protein - - - 0.00000000000000000000002036 109.0
CH2_k127_2932746_6 energy transducer activity K03646,K03832 - - 0.000001755 60.0
CH2_k127_2949998_0 Bacterial protein of unknown function (DUF839) K07093 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 447.0
CH2_k127_2949998_1 DNA mismatch repair protein MutT K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000003126 213.0
CH2_k127_2949998_2 Domain of unknown function (DUF4920) - - - 0.00000000000000001258 86.0
CH2_k127_2965701_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004721,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009987,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 8.224e-214 682.0
CH2_k127_2965701_1 Phenylalanine-4-hydroxylase K00500 - 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 454.0
CH2_k127_2965701_2 Nuclease K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 466.0
CH2_k127_2965701_3 Reduces the stability of FtsZ polymers in the presence of ATP K06916 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 378.0
CH2_k127_2965701_4 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 327.0
CH2_k127_2965701_5 Alpha beta K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000007707 231.0
CH2_k127_2965701_6 transcriptional K03719 - - 0.0000000000000000000000000000000000000000000000000000000000004358 214.0
CH2_k127_2965701_7 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000004053 197.0
CH2_k127_2965701_8 - - - - 0.000000003279 61.0
CH2_k127_2972468_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1053.0
CH2_k127_2972468_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.741e-273 850.0
CH2_k127_2972468_2 peptidase - - - 6.635e-195 629.0
CH2_k127_2972468_3 Putative Ig domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 577.0
CH2_k127_2972468_4 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 466.0
CH2_k127_2972468_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000004869 49.0
CH2_k127_2976401_0 Fungalysin metallopeptidase (M36) - - - 3.516e-202 667.0
CH2_k127_3005324_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 522.0
CH2_k127_3005324_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000003841 188.0
CH2_k127_3010013_0 general secretion pathway protein K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 326.0
CH2_k127_3010013_1 ATPase involved in cell division K09812 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000003099 237.0
CH2_k127_3010013_2 Carbon starvation protein K06200 - - 0.0000000000000000000000000000000000000000000000000005461 186.0
CH2_k127_3018509_0 E3 component of 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 1.645e-214 672.0
CH2_k127_3047315_0 trab family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005495 396.0
CH2_k127_3047315_1 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000002358 253.0
CH2_k127_3051495_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019353,GO:0019438,GO:0019752,GO:0033013,GO:0033014,GO:0033526,GO:0034641,GO:0042168,GO:0042440,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 500.0
CH2_k127_3051495_1 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 417.0
CH2_k127_3051495_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 383.0
CH2_k127_3051495_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 323.0
CH2_k127_3051495_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000003059 211.0
CH2_k127_3051495_5 SET domain K07117 - - 0.000000000000000000000000000000000000000000000000000000000808 205.0
CH2_k127_3051495_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family - - - 0.00000000000000000000000000000000000008726 144.0
CH2_k127_3051495_7 - - - - 0.000000000000000000000002371 106.0
CH2_k127_3114535_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K11745,K11747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 488.0
CH2_k127_3115824_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.36e-294 921.0
CH2_k127_3123137_0 chorismate mutase K04517,K14187 GO:0000166,GO:0003674,GO:0003824,GO:0004106,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 407.0
CH2_k127_3123137_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 388.0
CH2_k127_3123137_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000077 77.0
CH2_k127_312706_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K04090 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 527.0
CH2_k127_312706_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 309.0
CH2_k127_3148188_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 473.0
CH2_k127_3148188_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 445.0
CH2_k127_3148188_2 Concanavalin A-like lectin/glucanases superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 403.0
CH2_k127_3148188_3 PFAM glycosyl transferase family 9 - - - 0.00000000000000000000000000000000000000000000000000000002239 201.0
CH2_k127_3148188_4 Antidote-toxin recognition MazE, bacterial antitoxin K18829 - - 0.0000000000000000000003123 97.0
CH2_k127_3174865_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 2.921e-228 714.0
CH2_k127_3174865_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 434.0
CH2_k127_3220271_0 AAA domain - - - 0.000000000000000000000000000000000000000008363 159.0
CH2_k127_3223690_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.68e-205 655.0
CH2_k127_3223690_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 514.0
CH2_k127_3223690_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 362.0
CH2_k127_3223690_3 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000001091 197.0
CH2_k127_3223690_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000165 149.0
CH2_k127_3223690_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000000002997 102.0
CH2_k127_3253740_0 Histidine kinase - - - 1.375e-285 894.0
CH2_k127_3253740_1 penicillin-binding protein K05367 - 2.4.1.129 8.843e-217 693.0
CH2_k127_3253740_2 SMART Signal transduction response regulator, receiver region - - - 0.000000000000000000000000000000000000000000005688 172.0
CH2_k127_3253740_3 diguanylate cyclase - - - 0.000000000000000000001022 97.0
CH2_k127_329868_0 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000001259 158.0
CH2_k127_3325882_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 503.0
CH2_k127_3325882_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 392.0
CH2_k127_3325882_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 385.0
CH2_k127_3325882_3 Protein of unknown function (DUF808) K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 359.0
CH2_k127_3325882_4 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 313.0
CH2_k127_3325882_5 - - - - 0.00000000000000000000000000000000000000000000001051 181.0
CH2_k127_3325882_6 Cytochrome oxidase complex assembly protein 1 - - - 0.000000000000000000000000000000004907 139.0
CH2_k127_3325882_7 Belongs to the HSP15 family K04762 - - 0.00000000000000000000000000000001368 129.0
CH2_k127_3325882_8 - - - - 0.00001203 49.0
CH2_k127_3351084_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 413.0
CH2_k127_3351084_1 glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 375.0
CH2_k127_3351084_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001003 254.0
CH2_k127_3351084_3 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000004943 253.0
CH2_k127_3351084_4 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000008043 218.0
CH2_k127_3351084_5 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000006464 205.0
CH2_k127_3351084_6 ferredoxin - - - 0.0000000000000000000000000000000000003458 141.0
CH2_k127_3351084_7 - - - - 0.00000000000000000000000000000000004158 143.0
CH2_k127_3378321_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 562.0
CH2_k127_3378321_1 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003205 268.0
CH2_k127_3378321_10 tail collar domain protein K01406,K21449 - 3.4.24.40 0.00000000007165 73.0
CH2_k127_3378321_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000005082 213.0
CH2_k127_3378321_3 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000001324 208.0
CH2_k127_3378321_4 PIN domain - - - 0.0000000000000000000000000000000000000000000000000000005704 198.0
CH2_k127_3378321_5 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000009731 146.0
CH2_k127_3378321_6 toxin-antitoxin pair type II binding - - - 0.0000000000000000000000000000000000001184 142.0
CH2_k127_3378321_7 membrane transporter protein K07090 - - 0.00000000000000000000000000000006825 126.0
CH2_k127_3378321_8 - - - - 0.0000000000000004993 85.0
CH2_k127_3378321_9 - - - - 0.0000000000002485 77.0
CH2_k127_341577_0 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000003814 184.0
CH2_k127_341577_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000003584 100.0
CH2_k127_3426420_0 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 544.0
CH2_k127_3426420_1 Involved in the processing of the 5'end of 16S rRNA K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002458 245.0
CH2_k127_3438888_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 321.0
CH2_k127_3438888_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 291.0
CH2_k127_3438888_2 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000233 155.0
CH2_k127_3444924_0 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 320.0
CH2_k127_3444924_1 Protein of unknown function (DUF1348) K09958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003019 262.0
CH2_k127_3444924_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000004693 227.0
CH2_k127_3444924_3 - - - - 0.0000003065 55.0
CH2_k127_3490948_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 466.0
CH2_k127_3490948_1 Uncharacterized protein conserved in bacteria (DUF2145) - - - 0.0000000000000000000000000000000000000000000000000000000007545 213.0
CH2_k127_3490948_2 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000009011 85.0
CH2_k127_3490948_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000003068 51.0
CH2_k127_3490948_4 - - - - 0.000004993 55.0
CH2_k127_3519206_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1082.0
CH2_k127_3519206_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.00000000000000001425 89.0
CH2_k127_3532277_0 NAD dependent epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 306.0
CH2_k127_3532277_1 Transcriptional regulator - - - 0.00000000000000000000000000000002582 129.0
CH2_k127_3556808_0 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000002973 165.0
CH2_k127_3556808_1 SPFH domain-Band 7 family - - - 0.0000006275 54.0
CH2_k127_3608234_0 receptor K16092 - - 0.0000000000000000000000000001357 119.0
CH2_k127_3608234_1 involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0001857 51.0
CH2_k127_362357_0 penicillin-binding protein K05367 - 2.4.1.129 2.604e-263 829.0
CH2_k127_3633643_0 SNF2 family N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 443.0
CH2_k127_3633643_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000002888 64.0
CH2_k127_3645256_0 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 531.0
CH2_k127_3670609_0 COG0591 Na proline symporter - - - 7.272e-275 865.0
CH2_k127_3670609_1 Short-chain dehydrogenase reductase Sdr - - - 0.000000000000000000000002985 115.0
CH2_k127_3692452_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 6.9e-320 990.0
CH2_k127_3692452_1 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 579.0
CH2_k127_3692452_2 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 469.0
CH2_k127_3692452_3 Two component response regulator for the phosphate regulon K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 359.0
CH2_k127_3692452_4 Cytochrome C biogenesis K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007115 274.0
CH2_k127_3692452_5 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000001358 151.0
CH2_k127_3716144_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 4.56e-297 923.0
CH2_k127_3736068_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.695e-214 674.0
CH2_k127_3736068_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 438.0
CH2_k127_3736068_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000008389 239.0
CH2_k127_3736068_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000007703 81.0
CH2_k127_3791138_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 366.0
CH2_k127_3791138_1 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 302.0
CH2_k127_3801237_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000002873 228.0
CH2_k127_3801237_1 domain, Protein - - - 0.00000000000243 78.0
CH2_k127_3806886_0 COG2202 FOG PAS PAC domain K21025 - - 4.279e-202 649.0
CH2_k127_3806886_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 312.0
CH2_k127_3898495_0 asparaginyl-tRNA synthetase K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 8.179e-251 779.0
CH2_k127_3898495_1 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000007202 216.0
CH2_k127_3898495_2 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000003504 184.0
CH2_k127_3898495_3 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000008749 147.0
CH2_k127_3898495_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000185 137.0
CH2_k127_3898495_5 light absorption K01822,K21972 - 5.3.3.1 0.000000001353 59.0
CH2_k127_3933177_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.796e-212 676.0
CH2_k127_3933177_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 536.0
CH2_k127_3933177_2 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 467.0
CH2_k127_3933177_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 408.0
CH2_k127_3933177_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 312.0
CH2_k127_3939837_0 Diguanylate cyclase K21024 - 3.1.4.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 477.0
CH2_k127_3939837_1 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 434.0
CH2_k127_3939837_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 435.0
CH2_k127_3939837_3 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 402.0
CH2_k127_3939837_4 pteridine-dependent deoxygenase K18240 - 4.1.3.40,4.1.3.45 0.000000000000000000000000000000000000000000000000000000001475 213.0
CH2_k127_3939837_5 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000004981 175.0
CH2_k127_3953420_0 aminotransferase K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 544.0
CH2_k127_3953420_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 503.0
CH2_k127_3953420_2 pseudouridylate synthase K06175 - 5.4.99.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000008563 268.0
CH2_k127_3953420_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002178 257.0
CH2_k127_3953420_4 Lysophospholipase L1 and related esterases - - - 0.0000000000000000000000000000000000000000000000000000000000003624 219.0
CH2_k127_3953420_5 Sterol-binding protein K03690 - - 0.0000000000000000000000000000000000000000000000285 177.0
CH2_k127_3953420_6 repeat-containing protein - - - 0.00000000000000000000000000000000000000009083 172.0
CH2_k127_3953698_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 374.0
CH2_k127_397776_0 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000005863 227.0
CH2_k127_397776_1 Outer membrane receptor K02014,K16087 - - 0.00000000000000000000000000000000000000000000000000001564 209.0
CH2_k127_3980284_0 Transporter K03305 - - 7.434e-224 706.0
CH2_k127_3980284_1 Peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 611.0
CH2_k127_3980284_2 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003821 261.0
CH2_k127_3980284_3 cheY-homologous receiver domain K02658 - - 0.000000000000000000000000000000000000000000000000000000008346 207.0
CH2_k127_3980828_0 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 399.0
CH2_k127_3980828_1 Transmembrane protein 43 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002509 274.0
CH2_k127_3980828_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001909 263.0
CH2_k127_3980828_3 Nucleoside-diphosphate-sugar epimerases - - - 0.00000000000000000000000000000000000000000000004317 181.0
CH2_k127_3984188_0 PFAM CheB methylesterase - - - 0.0 1191.0
CH2_k127_3984188_1 Outer membrane protein W K07275 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007376 267.0
CH2_k127_3984188_2 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000396 178.0
CH2_k127_3984188_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000005822 176.0
CH2_k127_3984188_5 Transposase DDE domain group 1 - - - 0.000000000002951 72.0
CH2_k127_3984188_6 Bacterial-like globin - - - 0.0000000001312 62.0
CH2_k127_3985604_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002685 299.0
CH2_k127_3985604_1 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000006877 255.0
CH2_k127_3985604_2 ECF sigma factor - - - 0.00000000000000000000000000004708 123.0
CH2_k127_3985604_3 Methyltransferase domain - - - 0.0000000000004662 70.0
CH2_k127_4008006_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 334.0
CH2_k127_401506_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 361.0
CH2_k127_401506_1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 327.0
CH2_k127_401506_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000001285 145.0
CH2_k127_401506_3 - - - - 0.0000000000000000007768 91.0
CH2_k127_4034489_0 Large extracellular alpha-helical protein K06894 - - 0.0 1607.0
CH2_k127_4034489_1 penicillin-binding protein K05367 - 2.4.1.129 5.221e-278 875.0
CH2_k127_4034489_2 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 409.0
CH2_k127_4034489_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003314 274.0
CH2_k127_4034489_4 LuxR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000001251 241.0
CH2_k127_4034489_5 Belongs to the UPF0149 family K07039 - - 0.0000000000000001084 87.0
CH2_k127_4045716_0 elongation factor G K02355 - - 0.0 1045.0
CH2_k127_4045716_1 Catalyzes the hydrolytic cleavage of imides that range from linear to heterocyclic and that include hydantoins, dihydropyrimidines, and phthalimides K01464 - 3.5.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000134 276.0
CH2_k127_4045716_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000004947 187.0
CH2_k127_4045716_3 Outer membrane receptor - - - 0.00000000000000000000000000000000000005827 146.0
CH2_k127_4045716_4 Glycine zipper 2TM domain - - - 0.000000000000000000000000000000000001067 149.0
CH2_k127_4046479_0 Leucine-rich repeat (LRR) protein - - - 0.00000000001915 73.0
CH2_k127_4046479_1 Parallel beta-helix repeats - - - 0.000119 55.0
CH2_k127_4050325_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 450.0
CH2_k127_4050325_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007793 402.0
CH2_k127_4050325_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 389.0
CH2_k127_4050325_3 Bacterial PH domain K08981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 325.0
CH2_k127_4050325_4 Belongs to the peptidase S26 family - - - 0.00000000000000000000000000000000000000000000009261 171.0
CH2_k127_4050325_5 Putative member of DMT superfamily (DUF486) K09922 - - 0.0000000000000000000000000000000000000000000009268 168.0
CH2_k127_4050325_6 Bacterial PH domain K09167 - - 0.00000000000000006959 88.0
CH2_k127_4050325_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000001443 67.0
CH2_k127_4059225_0 MMPL family - - - 0.0 1158.0
CH2_k127_4059225_1 Protein of unknown function (DUF1329) - - - 3.364e-215 676.0
CH2_k127_4059225_2 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 314.0
CH2_k127_4059225_3 Protein of unknown function (DUF1302) - - - 0.0000000000000000000000000000000000000000000000000000000001152 206.0
CH2_k127_4059225_4 - - - - 0.0008668 42.0
CH2_k127_4059783_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 3.692e-248 771.0
CH2_k127_4059783_1 Belongs to the aldehyde dehydrogenase family K00146,K09472 - 1.2.1.39,1.2.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 312.0
CH2_k127_4059783_2 Phage-associated protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 283.0
CH2_k127_4059783_3 alanine dehydrogenase K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 280.0
CH2_k127_4073616_0 Peptidase dimerisation domain K13049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 400.0
CH2_k127_4073616_1 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002371 241.0
CH2_k127_4073616_2 FG-GAP repeat - - - 0.00000000000000000000000000000000000000000469 162.0
CH2_k127_4073616_3 Flagellar basal body rod K02396,K03333 - 1.1.3.6 0.000000002358 65.0
CH2_k127_4198330_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 2.572e-194 612.0
CH2_k127_4198330_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 541.0
CH2_k127_4198330_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 514.0
CH2_k127_4198330_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 485.0
CH2_k127_4198330_4 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002466 260.0
CH2_k127_4198330_5 Protein of unknown function (DUF721) - - - 0.000000000002722 73.0
CH2_k127_4203952_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1303.0
CH2_k127_4203952_1 GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.387e-245 760.0
CH2_k127_4203952_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 330.0
CH2_k127_4203952_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005254 262.0
CH2_k127_4203952_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005886 259.0
CH2_k127_4203952_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000008288 218.0
CH2_k127_4203952_6 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003366 213.0
CH2_k127_4203952_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000000001237 104.0
CH2_k127_4203952_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000009178 50.0
CH2_k127_4213510_0 Nucleoside-diphosphate-sugar epimerase K07276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002099 254.0
CH2_k127_4213510_1 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.000000000000000000000000000000000000000009893 159.0
CH2_k127_4213510_2 Acyltransferase - - - 0.0000000000000000000000000000000000001268 143.0
CH2_k127_4215844_0 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 - - 9.436e-247 767.0
CH2_k127_4215844_1 exonuclease K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 313.0
CH2_k127_4215844_2 hemolysin III K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003179 249.0
CH2_k127_4215844_3 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001422 252.0
CH2_k127_4220880_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 2.546e-208 654.0
CH2_k127_4220880_1 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000002962 91.0
CH2_k127_4228052_0 Zinc metalloprotease (Elastase) K20274 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 359.0
CH2_k127_4228052_1 SMI1 / KNR4 family - - - 0.0000000000000000002895 100.0
CH2_k127_4229473_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 584.0
CH2_k127_4229473_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 359.0
CH2_k127_4229473_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 319.0
CH2_k127_4229473_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000009615 232.0
CH2_k127_4229473_4 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000001398 216.0
CH2_k127_4229473_5 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000002078 214.0
CH2_k127_4229473_6 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000000000961 182.0
CH2_k127_4229473_7 Oar protein - - - 0.0000000000000000000000000000003545 127.0
CH2_k127_4229473_8 Trm112p-like protein - - - 0.00000000000000000008105 95.0
CH2_k127_4250930_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1032.0
CH2_k127_4276399_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 518.0
CH2_k127_4276399_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 468.0
CH2_k127_4276399_2 polyphosphate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 335.0
CH2_k127_4276399_3 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001133 275.0
CH2_k127_4276399_4 Belongs to the peptidase S8 family K14645 - - 0.00000002378 65.0
CH2_k127_4278180_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.182e-318 979.0
CH2_k127_4278180_1 AlkA N-terminal domain K13529 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 441.0
CH2_k127_4278180_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000002818 188.0
CH2_k127_4278180_3 Sugar efflux transporter for intercellular exchange K15383 - - 0.0000000000000000000108 98.0
CH2_k127_4296044_0 Y_Y_Y domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007843 264.0
CH2_k127_4298126_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1042.0
CH2_k127_4298126_1 TraB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 308.0
CH2_k127_4298126_2 Domain of unknown function (DUF1820) - - - 0.0000000000000000000000000000000000003544 143.0
CH2_k127_4298126_3 GtrA-like protein - - - 0.0000000000000000000000000000000001611 136.0
CH2_k127_4298126_4 Biopolymer transport protein K03559 - - 0.00000000000000002313 89.0
CH2_k127_4298126_5 OmpA-like transmembrane domain - - - 0.000000001963 66.0
CH2_k127_4298126_6 YcgL domain-containing protein K09902 - - 0.00000089 51.0
CH2_k127_4311935_0 Among the AAA ATPases, the YifB protease family belongs to the Helix 2 insert clade K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006382 591.0
CH2_k127_4311935_1 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 530.0
CH2_k127_4311935_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000001387 201.0
CH2_k127_4311935_3 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000002972 198.0
CH2_k127_4311935_4 protein conserved in bacteria K09806 - - 0.0000000000000000000000509 100.0
CH2_k127_4311935_5 Endonuclease Exonuclease Phosphatase K07004 - - 0.0000000000000000000002846 115.0
CH2_k127_4311935_6 antibiotic catabolic process - - - 0.0000000466 68.0
CH2_k127_4311935_7 NACHT, and Ankyrin domain protein K21440 - - 0.00000006203 62.0
CH2_k127_4311935_8 Tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase K10799 GO:0000209,GO:0000226,GO:0000228,GO:0000242,GO:0000278,GO:0000781,GO:0000784,GO:0000922,GO:0003674,GO:0003824,GO:0003950,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005643,GO:0005654,GO:0005694,GO:0005737,GO:0005794,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006355,GO:0006357,GO:0006464,GO:0006468,GO:0006471,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007052,GO:0007063,GO:0007088,GO:0007346,GO:0008104,GO:0008150,GO:0008152,GO:0008270,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010638,GO:0010639,GO:0010646,GO:0010647,GO:0010948,GO:0012505,GO:0015630,GO:0016020,GO:0016043,GO:0016310,GO:0016567,GO:0016604,GO:0016740,GO:0016757,GO:0016763,GO:0018105,GO:0018107,GO:0018193,GO:0018209,GO:0018210,GO:0019219,GO:0019222,GO:0019538,GO:0022402,GO:0022607,GO:0023051,GO:0023056,GO:0030111,GO:0030162,GO:0030177,GO:0031090,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032204,GO:0032205,GO:0032206,GO:0032210,GO:0032212,GO:0032268,GO:0032270,GO:0032446,GO:0032991,GO:0033036,GO:0033043,GO:0033044,GO:0033045,GO:0033046,GO:0033047,GO:0033048,GO:0033365,GO:0034091,GO:0034092,GO:0034182,GO:0034183,GO:0034502,GO:0034613,GO:0036211,GO:0042176,GO:0042393,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043392,GO:0043412,GO:0044085,GO:0044087,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044451,GO:0044454,GO:0044464,GO:0045732,GO:0045786,GO:0045839,GO:0045862,GO:0045875,GO:0045893,GO:0045930,GO:0045934,GO:0045935,GO:0045944,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0050789,GO:0050790,GO:0050794,GO:0051052,GO:0051053,GO:0051054,GO:0051098,GO:0051100,GO:0051101,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051225,GO:0051246,GO:0051247,GO:0051252,GO:0051254,GO:0051338,GO:0051347,GO:0051641,GO:0051726,GO:0051783,GO:0051784,GO:0051972,GO:0051973,GO:0051983,GO:0051985,GO:0060255,GO:0060828,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070198,GO:0070212,GO:0070213,GO:0070647,GO:0070727,GO:0070925,GO:0071704,GO:0071840,GO:0072686,GO:0080090,GO:0090263,GO:0090364,GO:0097110,GO:0097431,GO:0098687,GO:1901564,GO:1902680,GO:1902850,GO:1903047,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1903506,GO:1903508,GO:1904353,GO:1904355,GO:1904356,GO:1904357,GO:1904358,GO:1904742,GO:1904743,GO:1904907,GO:1904908,GO:2000058,GO:2000060,GO:2000112,GO:2000278,GO:2000573,GO:2001141,GO:2001251,GO:2001252 2.4.2.30 0.00000006636 64.0
CH2_k127_4313569_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.038e-223 700.0
CH2_k127_4313569_1 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000001055 244.0
CH2_k127_4340047_0 lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 447.0
CH2_k127_4340047_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000003403 233.0
CH2_k127_4340047_2 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000000002302 209.0
CH2_k127_4340047_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000001134 130.0
CH2_k127_4347504_0 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000008075 157.0
CH2_k127_4347504_1 General secretion pathway protein J K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0000000000000000000000000000002676 131.0
CH2_k127_4347504_2 COG2165 Type II secretory pathway, pseudopilin PulG K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000009067 98.0
CH2_k127_4347504_3 Prokaryotic N-terminal methylation motif - - - 0.0000001956 59.0
CH2_k127_4377075_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 520.0
CH2_k127_4377075_1 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 351.0
CH2_k127_4377075_10 Domain of unknown function (DUF4926) - - - 0.0000000000000000001456 96.0
CH2_k127_4377075_11 PFAM Transposase DDE domain - - - 0.00000000000000004441 83.0
CH2_k127_4377075_12 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000003174 70.0
CH2_k127_4377075_2 of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002261 284.0
CH2_k127_4377075_3 Protein of unknown function (DUF3034) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005893 256.0
CH2_k127_4377075_4 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000002875 228.0
CH2_k127_4377075_5 Belongs to the DnaA family. HdA subfamily K10763 - - 0.000000000000000000000000000000000000000000000001846 181.0
CH2_k127_4377075_6 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000000000001807 160.0
CH2_k127_4377075_7 protein conserved in bacteria K09938 - - 0.00000000000000000000000000001589 132.0
CH2_k127_4377075_8 - - - - 0.00000000000000000000000002162 111.0
CH2_k127_4377075_9 Bacterial-like globin K06886 - - 0.0000000000000000000000447 107.0
CH2_k127_4404690_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1229.0
CH2_k127_4404690_1 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 567.0
CH2_k127_4404690_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 451.0
CH2_k127_4404690_3 - - - - 0.000000000000000000000007786 109.0
CH2_k127_4407384_0 cellulose binding - - - 0.000000000000000000000000000000000000000000002541 177.0
CH2_k127_4407384_1 protein typical subtype - - - 0.000000000002542 77.0
CH2_k127_4409567_0 regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009492 352.0
CH2_k127_4409567_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000005189 173.0
CH2_k127_4409567_2 Polyketide cyclase - - - 0.000000000000000000000000000000000000000000001174 178.0
CH2_k127_4420131_0 Large extracellular alpha-helical protein K06894 - - 1.5e-323 1040.0
CH2_k127_4420131_1 penicillin-binding protein K05367 - 2.4.1.129 0.000000001723 62.0
CH2_k127_4440418_0 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 449.0
CH2_k127_4440418_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 403.0
CH2_k127_4440418_2 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000081 346.0
CH2_k127_4440418_3 Signal transduction histidine kinase K07637 - 2.7.13.3 0.000000000000000001419 88.0
CH2_k127_4440418_4 - - - - 0.0000008108 58.0
CH2_k127_4459000_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 1.055e-225 707.0
CH2_k127_4459000_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000001364 184.0
CH2_k127_4459000_2 - - - - 0.000000000000000000000000000000000000000000000001754 180.0
CH2_k127_4459000_3 cellulose binding - - - 0.00000000000000000000000000000000000000000000007342 191.0
CH2_k127_4459000_4 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000003935 167.0
CH2_k127_4459000_5 Hep Hag repeat protein K11904,K21449 - - 0.000000000000000001353 99.0
CH2_k127_4459000_6 - - - - 0.00000001312 61.0
CH2_k127_4461582_0 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 489.0
CH2_k127_4461582_1 Part of the ABC transporter complex cysAWTP involved in sulfate thiosulfate import K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 428.0
CH2_k127_4461582_2 Mut7-C RNAse domain - - - 0.00000000000000000000000000000005752 128.0
CH2_k127_4461582_3 InterPro IPR007367 - - - 0.000000000000000000000007601 102.0
CH2_k127_4464770_0 In Escherichia coli this enzyme appears to be an NAD NADP -dependent succinate semialdehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 542.0
CH2_k127_4464770_1 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008165 257.0
CH2_k127_4465399_0 Catalyzes the formation of 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol from 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol K03184,K18800 - - 0.0000000000000000000000000000000000000000000000000000000000000003839 232.0
CH2_k127_4465399_1 hydroxylase K03185 - - 0.000000000000000000000000000000000000000000000000001939 188.0
CH2_k127_4468118_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 329.0
CH2_k127_4468118_1 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008249 261.0
CH2_k127_4468118_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000002034 185.0
CH2_k127_4469661_0 Outer membrane receptor proteins mostly Fe transport - - - 0.0 1286.0
CH2_k127_4469661_1 Belongs to the glycosyl hydrolase 13 family - - - 0.0 1029.0
CH2_k127_4469661_2 Alpha-amylase domain - - - 9.495e-294 925.0
CH2_k127_4469661_3 Periplasmic binding protein domain K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 458.0
CH2_k127_4513163_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 7.086e-245 775.0
CH2_k127_4513163_1 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 405.0
CH2_k127_4513163_2 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 313.0
CH2_k127_4513163_3 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.0000000000000000000000000000000000000000000000000000000000002679 220.0
CH2_k127_4518962_0 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 348.0
CH2_k127_4518962_1 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 318.0
CH2_k127_4518962_2 Oxidoreductase K09471 - - 0.00000000000000000000000001963 112.0
CH2_k127_4518962_3 - - - - 0.000000001376 63.0
CH2_k127_4518962_4 Domain of Unknown Function (DUF349) - - - 0.000003531 54.0
CH2_k127_4555869_0 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 352.0
CH2_k127_4555869_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000002727 226.0
CH2_k127_4555869_2 calcium- and calmodulin-responsive adenylate cyclase activity K01406,K07004 - 3.4.24.40 0.00000000000000000000000000000000000000001778 159.0
CH2_k127_4555869_3 - - - - 0.0000000000000000000000000000000374 136.0
CH2_k127_4555869_4 TIGRFAM death-on-curing family protein K07341 - - 0.000000000000000000000000001044 113.0
CH2_k127_4555869_5 Addiction module antidote - - - 0.000000000000000001863 87.0
CH2_k127_4560658_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 6.131e-318 980.0
CH2_k127_4560658_1 Succinate dehydrogenase, hydrophobic anchor subunit K00242 - - 0.0000000000000000000000000000000004921 136.0
CH2_k127_4560658_2 - - - - 0.0000008322 52.0
CH2_k127_4560658_3 succinate dehydrogenase K00241 - - 0.0001846 44.0
CH2_k127_4573833_0 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 481.0
CH2_k127_4573833_1 Transcriptional regulator K10914 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0017076,GO:0019001,GO:0019219,GO:0019222,GO:0030551,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032561,GO:0035438,GO:0036094,GO:0043167,GO:0043168,GO:0046983,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 321.0
CH2_k127_4573833_2 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000004143 240.0
CH2_k127_4573833_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000002338 192.0
CH2_k127_4573833_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000006036 158.0
CH2_k127_4591487_0 Pkd domain containing protein K12567 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 326.0
CH2_k127_4591487_1 Lamin Tail Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006005 254.0
CH2_k127_4591487_2 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000006383 150.0
CH2_k127_4591487_3 alpha-L-arabinofuranosidase - - - 0.000000000008281 78.0
CH2_k127_4636504_0 Tetratricopeptide repeat - - - 0.000000000000000001077 95.0
CH2_k127_4636504_1 cellulose binding - - - 0.0000000000000007232 92.0
CH2_k127_4671870_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0 1045.0
CH2_k127_4671870_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000003422 222.0
CH2_k127_4688605_0 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1158.0
CH2_k127_4688605_1 Mur ligase middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 525.0
CH2_k127_4688605_2 Peptidase family S51 K13282 - 3.4.15.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 419.0
CH2_k127_4688605_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0001803 47.0
CH2_k127_4708299_0 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 456.0
CH2_k127_4708299_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 394.0
CH2_k127_4708299_2 Peptidase family M3 K01414 - 3.4.24.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 350.0
CH2_k127_4708299_3 peptidoglycan-binding protein, lysm - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 339.0
CH2_k127_4708299_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000002202 262.0
CH2_k127_4708299_5 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000001308 247.0
CH2_k127_4708299_6 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000002071 189.0
CH2_k127_4719162_0 lysine biosynthetic process via aminoadipic acid - - - 1.739e-205 664.0
CH2_k127_4719162_1 Ornithine cyclodeaminase/mu-crystallin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 482.0
CH2_k127_4719162_2 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000001163 234.0
CH2_k127_4719162_3 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.000000000000000000000000000000000000000000000000000000000000001786 221.0
CH2_k127_4719162_4 Transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000003037 179.0
CH2_k127_471978_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 325.0
CH2_k127_471978_1 - - - - 0.00000000000000626 81.0
CH2_k127_4726424_0 general secretion pathway protein D K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 485.0
CH2_k127_4726424_1 PFAM Type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 434.0
CH2_k127_4726424_2 Type II secretion system protein C - - - 0.000000000000003023 83.0
CH2_k127_4730900_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 1.663e-196 623.0
CH2_k127_4730900_1 acetyltransferase K06977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002657 248.0
CH2_k127_4730900_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000009336 229.0
CH2_k127_4730900_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000002018 224.0
CH2_k127_4781308_0 interspecies interaction between organisms - - - 0.0000000000000000000000000000000000000000000000000000000000000005618 231.0
CH2_k127_4781308_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000007166 201.0
CH2_k127_4781308_2 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000000000000000000000000000000000414 183.0
CH2_k127_4781308_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000002371 86.0
CH2_k127_4797589_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 387.0
CH2_k127_4821392_0 COG2771 DNA-binding HTH domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 312.0
CH2_k127_4821392_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000001908 89.0
CH2_k127_4822195_0 GGDEF Domain - - - 0.000000000000000000000000000000000000000000000000000000004721 220.0
CH2_k127_4822195_1 ERAP1-like C-terminal domain - - - 0.000001773 51.0
CH2_k127_4824072_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 553.0
CH2_k127_4824072_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 361.0
CH2_k127_4824072_2 Belongs to the Orn Lys Arg decarboxylase class-II family K12526 - 2.7.2.4,4.1.1.20 0.00000000000000000000000000000000005177 135.0
CH2_k127_4863123_0 Domain of unknown function DUF11 - - - 0.00000000009544 74.0
CH2_k127_4877416_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 311.0
CH2_k127_4877416_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 300.0
CH2_k127_4877416_2 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 299.0
CH2_k127_4877416_3 protein conserved in bacteria K09921 - - 0.000000000000000000000000000000000000000000000000000000000000000000004677 242.0
CH2_k127_4897034_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 508.0
CH2_k127_4897034_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 317.0
CH2_k127_4897034_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 310.0
CH2_k127_4897034_3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000008742 216.0
CH2_k127_4897034_4 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000592 175.0
CH2_k127_4897034_5 Lytic murein transglycosylase K08309 - - 0.00000000000000000002071 92.0
CH2_k127_4918554_0 ABC transporter transmembrane region - - - 5.631e-293 909.0
CH2_k127_4918554_1 Activates fatty acids by binding to coenzyme A - - - 2.477e-264 826.0
CH2_k127_4918554_10 Domain of unknown function (DUF5076) - - - 0.00000001267 61.0
CH2_k127_4918554_2 aminopeptidase n - - - 3.394e-229 722.0
CH2_k127_4918554_3 Catalyzes the formation of 3,6-dideoxy-D-glycero-D-glycero-4-hexulose K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003344 268.0
CH2_k127_4918554_4 Family of unknown function (DUF695) - - - 0.000000000000000000000000000000000000000000000000000003496 201.0
CH2_k127_4918554_5 phenylacetate-CoA ligase activity - - - 0.0000000000000000000000000000000000000000002113 165.0
CH2_k127_4918554_6 Domain of unknown function (DUF5062) - - - 0.0000000000000000000000000000000000007555 141.0
CH2_k127_4918554_7 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000001671 136.0
CH2_k127_4918554_8 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000003679 124.0
CH2_k127_4918554_9 Domain of unknown function (DUF5076) - - - 0.000000001582 59.0
CH2_k127_4920960_0 Sodium ABC transporter permease K09696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 379.0
CH2_k127_4920960_1 abc transporter atp-binding protein K09697 - 3.6.3.7 0.000000000000000000000000000000000000000006983 154.0
CH2_k127_4920960_2 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712 - - 0.000000000000001743 79.0
CH2_k127_4920960_3 MltA-interacting MipA family protein - - - 0.0007388 49.0
CH2_k127_4928888_0 Putative neutral zinc metallopeptidase K01387,K06872,K07054 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.4.24.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 310.0
CH2_k127_4928888_1 - - - - 0.00000000000000000000009306 107.0
CH2_k127_4935848_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1035.0
CH2_k127_4935848_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000197 241.0
CH2_k127_4935848_2 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.0000000000000000000000000000000000000000000000000000149 197.0
CH2_k127_500745_0 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 401.0
CH2_k127_500745_1 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 GO:0003674,GO:0003824,GO:0004057,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016598,GO:0016740,GO:0016746,GO:0016755,GO:0019538,GO:0019941,GO:0030163,GO:0036211,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000004161 270.0
CH2_k127_500745_2 - - - - 0.00000000000000000000000000000000000002668 157.0
CH2_k127_5009748_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 324.0
CH2_k127_5009748_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000002056 254.0
CH2_k127_5009748_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000008318 126.0
CH2_k127_5039181_0 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000001068 222.0
CH2_k127_5039181_1 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000000000000000000000000345 208.0
CH2_k127_5039181_2 Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000417 199.0
CH2_k127_5044083_0 Sulfate adenylyltransferase subunit 2 K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 503.0
CH2_k127_5044083_1 glucose sorbosone K00117,K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 421.0
CH2_k127_5044083_2 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 364.0
CH2_k127_5049954_0 Castor and Pollux, part of voltage-gated ion channel - - - 1.256e-287 895.0
CH2_k127_5049954_1 Amidohydrolase family - - - 4.407e-195 618.0
CH2_k127_5049954_2 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 350.0
CH2_k127_5049954_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000001263 208.0
CH2_k127_5049954_4 Protein of unknown function (DUF3014) - - - 0.000000000000000000000000000000000000000000000000000000003128 210.0
CH2_k127_5059664_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 340.0
CH2_k127_505971_0 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000002207 264.0
CH2_k127_505971_1 COG4970 Tfp pilus assembly protein FimT K08084 - - 0.000000000000000000000000003837 118.0
CH2_k127_5063797_0 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008563 268.0
CH2_k127_5063797_1 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000001387 256.0
CH2_k127_5063797_2 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000006467 205.0
CH2_k127_5063797_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000004242 69.0
CH2_k127_5091316_0 twitching motility protein K02670 - - 1.059e-218 681.0
CH2_k127_5091316_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 435.0
CH2_k127_5091316_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 370.0
CH2_k127_5091316_3 Putative prokaryotic signal transducing protein - - - 0.0000000001514 64.0
CH2_k127_5094191_0 transport system involved in gliding motility, auxiliary component - - - 1.951e-211 671.0
CH2_k127_5094191_1 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000001866 161.0
CH2_k127_5105145_0 Belongs to the peptidase S8 family - - - 1.154e-204 651.0
CH2_k127_5105145_1 Lysine-specific metallo-endopeptidase K08646 - 3.4.24.20 0.0000000000000000000000000000000000816 140.0
CH2_k127_5105145_2 exopeptidase activity - - - 0.000000000000000000000000000000009527 143.0
CH2_k127_5132531_0 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 401.0
CH2_k127_5132531_1 Pilus assembly protein K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005315 294.0
CH2_k127_5132531_2 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.00000000000000000000002782 105.0
CH2_k127_5132531_3 electron transfer flavoprotein beta subunit K03521 - - 0.0000000000000001143 79.0
CH2_k127_5154662_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 8.925e-194 616.0
CH2_k127_5154662_1 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000002641 228.0
CH2_k127_5158543_0 Rod shape-determining protein K03569 - - 9.219e-201 630.0
CH2_k127_5158543_1 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000001043 244.0
CH2_k127_5158543_2 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.000000000000000000000000000000000000000000001103 172.0
CH2_k127_5158543_3 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000002578 162.0
CH2_k127_5158543_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000004999 92.0
CH2_k127_5184673_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 558.0
CH2_k127_5184673_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000001343 151.0
CH2_k127_5184673_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000001077 107.0
CH2_k127_5198389_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 331.0
CH2_k127_5198389_1 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000006781 246.0
CH2_k127_5198389_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000007801 105.0
CH2_k127_522613_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K04090 - 1.2.7.8 0.0 1346.0
CH2_k127_522613_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000001304 79.0
CH2_k127_5294525_0 GGDEF domain - - - 4.027e-244 769.0
CH2_k127_5339226_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 364.0
CH2_k127_5339226_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 294.0
CH2_k127_5339226_2 Nhl repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000003826 239.0
CH2_k127_5348752_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 500.0
CH2_k127_5348752_1 NapC/NirT cytochrome c family, N-terminal region K02569,K03532 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 341.0
CH2_k127_5348752_2 Nitrate reductase cytochrome c-type subunit (NapB) K02568 - - 0.00000000000000000000000000000000000000000000000000000000004895 211.0
CH2_k127_5348752_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000001829 164.0
CH2_k127_5348929_0 Histidine ammonia-lyase K01745 - 4.3.1.3 1.453e-277 861.0
CH2_k127_5348929_1 7TMR-DISM extracellular 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 427.0
CH2_k127_5352276_0 PFAM BNR Asp-box repeat - - - 1.17e-263 850.0
CH2_k127_5352276_1 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 487.0
CH2_k127_5352276_2 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001181 244.0
CH2_k127_5404115_0 Belongs to the beta-ketoacyl-ACP synthases family - - - 6.149e-229 731.0
CH2_k127_5417313_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 513.0
CH2_k127_5417313_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 379.0
CH2_k127_5417313_2 stress-induced protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 317.0
CH2_k127_5417313_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000004233 250.0
CH2_k127_5417313_4 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000000005749 198.0
CH2_k127_5421926_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 285.0
CH2_k127_5421926_1 - - - - 0.0000000000000000000000000000000000000000000005179 173.0
CH2_k127_5439512_0 Tetratricopeptide repeat - - - 0.000000000000007115 82.0
CH2_k127_5439512_1 heat shock protein binding K05516,K05801,K18481 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.0000006101 59.0
CH2_k127_5442600_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008460,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 561.0
CH2_k127_5442600_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 280.0
CH2_k127_5442600_2 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000000000000001068 188.0
CH2_k127_5444724_0 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000218 194.0
CH2_k127_5444724_1 protein conserved in bacteria K09793 - - 0.00000000000000000000000000000000000000000005493 166.0
CH2_k127_5444724_2 Putative diguanylate phosphodiesterase - - - 0.0000002405 55.0
CH2_k127_5444724_3 Transfers the fatty acyl group on membrane lipoproteins - - - 0.0008753 49.0
CH2_k127_5460553_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.336e-274 856.0
CH2_k127_5463796_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 373.0
CH2_k127_5463796_1 - - - - 0.00000000000000000000000000000265 130.0
CH2_k127_5463796_2 response regulator receiver K02487,K06596 - - 0.000000000000003136 81.0
CH2_k127_546692_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 9.466e-287 891.0
CH2_k127_546692_1 Participates in both transcription termination and antitermination K02600 - - 1.387e-244 762.0
CH2_k127_546692_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000002767 171.0
CH2_k127_546692_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000004063 145.0
CH2_k127_5505711_0 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 466.0
CH2_k127_5505711_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001329 258.0
CH2_k127_5505711_2 Protein of unknown function (DUF1778) - - - 0.00000000000000000000003333 99.0
CH2_k127_5527987_0 protein conserved in bacteria - - - 2.857e-215 681.0
CH2_k127_5527987_1 Regulatory protein, FmdB family - - - 0.00000000000000000000000000005459 123.0
CH2_k127_5535031_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 304.0
CH2_k127_5535031_1 Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000000000003255 189.0
CH2_k127_5535031_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000006708 126.0
CH2_k127_55703_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000433 265.0
CH2_k127_55703_1 Immune inhibitor A peptidase M6 K09607 - - 0.0001854 55.0
CH2_k127_557749_0 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000082 403.0
CH2_k127_557749_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001669 273.0
CH2_k127_557749_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000007154 132.0
CH2_k127_5593005_0 acetoin utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 363.0
CH2_k127_5593005_1 adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000003222 206.0
CH2_k127_5593005_2 Histidine kinase - - - 0.0000000001366 65.0
CH2_k127_5633954_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K13482 - 1.17.1.4 2.186e-215 686.0
CH2_k127_5633954_1 CO dehydrogenase flavoprotein C-terminal domain K13481 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 432.0
CH2_k127_5633954_2 Helicase K03579 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 309.0
CH2_k127_5635416_0 Peptidase M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 527.0
CH2_k127_5635416_1 dna-binding protein K03746 - - 0.000000000000001015 81.0
CH2_k127_5645194_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004242 274.0
CH2_k127_5645194_1 - - - - 0.0000000000000000000559 101.0
CH2_k127_5645194_2 PFAM CcdB protein K19163 - - 0.0000000000000000005756 94.0
CH2_k127_5645194_3 Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid K19164 - - 0.000000000000000006258 87.0
CH2_k127_5706629_0 serine threonine protein kinase K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 405.0
CH2_k127_5706629_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.00000000000000000000000000002019 128.0
CH2_k127_5706629_2 DNA-templated transcription, initiation - - - 0.0000000000000000000000001156 115.0
CH2_k127_5738827_0 Belongs to the class I fructose-bisphosphate aldolase family K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 564.0
CH2_k127_5738827_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 474.0
CH2_k127_5738827_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000008582 227.0
CH2_k127_5738827_3 - - - - 0.00000000000000000000000000000000000000000000000005031 194.0
CH2_k127_5748845_0 transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 492.0
CH2_k127_5748845_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000001729 198.0
CH2_k127_5757294_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 540.0
CH2_k127_5757294_1 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 359.0
CH2_k127_5760224_0 Protein tyrosine kinase K11912 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 327.0
CH2_k127_5760224_1 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008391 263.0
CH2_k127_5760224_2 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000003519 132.0
CH2_k127_5822526_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.115e-232 728.0
CH2_k127_5822526_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 597.0
CH2_k127_5822526_2 Single-stranded-DNA-specific exonuclease K07462 - - 0.0000000000000000000000000006275 117.0
CH2_k127_5824659_0 2,4-dienoyl-coa reductase K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 464.0
CH2_k127_5827506_0 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 599.0
CH2_k127_5827506_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000002529 206.0
CH2_k127_5827506_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000001759 173.0
CH2_k127_5837088_0 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000028 284.0
CH2_k127_5837088_1 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000001071 257.0
CH2_k127_5837088_2 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.00000000000000000000001513 106.0
CH2_k127_5857480_0 Acetylglutamate kinase K22478 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 7.319e-201 632.0
CH2_k127_5857480_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000002508 82.0
CH2_k127_5857929_0 Peptidase family M23 - - - 0.0000000000000000000000000000000002 143.0
CH2_k127_5857929_1 Hep Hag repeat protein K21449 - - 0.0000000000000000000000000000001036 138.0
CH2_k127_5857929_2 Domain of unknown function (DUF4123) - - - 0.000002125 55.0
CH2_k127_5867873_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 3.701e-248 781.0
CH2_k127_5867873_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 331.0
CH2_k127_5867873_2 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000005513 134.0
CH2_k127_5883927_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 577.0
CH2_k127_5883927_1 DNA polymerase beta domain protein region - - - 0.000000000000000000000000000008369 121.0
CH2_k127_5883927_2 TIGRFAM nucleotidyltransferase substrate binding protein, HI0074 - - - 0.0000001244 54.0
CH2_k127_5954499_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000002106 196.0
CH2_k127_5954499_1 Methyltransferase - - - 0.00000000000000000000000000000000000000000000007796 172.0
CH2_k127_5954499_2 Capsular polysaccharide synthesis protein K09809 - 2.7.8.12 0.00000000000000000000000000000000000000000003327 170.0
CH2_k127_5954499_3 Peptidase family S41 - - - 0.00005615 53.0
CH2_k127_596394_0 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000002892 187.0
CH2_k127_596394_1 - - - - 0.00000000000000000000000002762 114.0
CH2_k127_596394_2 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.00000000000000000004297 91.0
CH2_k127_596394_3 acyl-coa dehydrogenase - - - 0.00000000000000002345 85.0
CH2_k127_5988572_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 3.463e-268 838.0
CH2_k127_5988572_1 RNA polymerase sigma factor RpoH K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 413.0
CH2_k127_5988572_2 membrane protein, terc K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 394.0
CH2_k127_5988572_3 PFAM NADH ubiquinone oxidoreductase complex I intermediate-associated protein 30 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001169 245.0
CH2_k127_5988572_4 - - - - 0.00000003003 63.0
CH2_k127_5988572_5 prohibitin homologues - - - 0.000001286 50.0
CH2_k127_5994038_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 1.261e-275 861.0
CH2_k127_5994038_1 ArsR family transcriptional regulator - - - 0.00000000000000000000000002416 109.0
CH2_k127_6021051_0 COG1834 N-Dimethylarginine dimethylaminohydrolase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 385.0
CH2_k127_6021051_1 Tetratricopeptide repeat K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000004749 204.0
CH2_k127_6021051_2 Cleaved Adhesin Domain - - - 0.000000000000000000000000000000001597 134.0
CH2_k127_6021051_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000005502 60.0
CH2_k127_6021051_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0000302,GO:0000988,GO:0000990,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0006950,GO:0006979,GO:0008150,GO:0009266,GO:0009405,GO:0009408,GO:0009410,GO:0009605,GO:0009607,GO:0009628,GO:0009636,GO:0009889,GO:0010035,GO:0010468,GO:0010556,GO:0016987,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0043207,GO:0043254,GO:0044087,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0075136,GO:0080090,GO:0090034,GO:0097159,GO:0140110,GO:1901363,GO:1901700,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.0000008099 59.0
CH2_k127_6027372_0 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 334.0
CH2_k127_6044626_0 Divalent cation transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 459.0
CH2_k127_6044626_1 HutD - - - 0.0000000000000000000000001807 120.0
CH2_k127_6044626_2 CoA-transferase family III - - - 0.0000000000000000002075 88.0
CH2_k127_6044626_3 Tetratricopeptide repeat - - - 0.0004132 43.0
CH2_k127_6049130_0 Acts as a magnesium transporter K06213 - - 7.923e-197 622.0
CH2_k127_6049130_1 acid dehydrogenase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000002231 178.0
CH2_k127_6049130_2 histidine kinase A domain protein K07679 - 2.7.13.3 0.0000000000000000000005633 109.0
CH2_k127_6049596_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000001637 166.0
CH2_k127_6049596_1 Outer membrane receptor for ferrienterochelin and colicins - - - 0.0007619 44.0
CH2_k127_6049888_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005011 283.0
CH2_k127_6049888_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000001714 97.0
CH2_k127_6049888_2 - - - - 0.0000000000005085 81.0
CH2_k127_6073124_0 Belongs to the glutamate synthase family - - - 1.797e-249 781.0
CH2_k127_6073124_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 306.0
CH2_k127_6073124_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000348 236.0
CH2_k127_6073124_3 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000001425 146.0
CH2_k127_6073124_4 - - - - 0.00000000000000000000000000001002 125.0
CH2_k127_6136719_0 2-nitropropane dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 606.0
CH2_k127_6136719_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 331.0
CH2_k127_6136719_2 Belongs to the LOG family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004432 273.0
CH2_k127_6136719_3 transcriptional regulator - - - 0.0000000000000000000000000001858 123.0
CH2_k127_6136719_4 Beta-ketoacyl synthase - - - 0.000005076 51.0
CH2_k127_6166427_0 Helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 521.0
CH2_k127_6166427_1 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 396.0
CH2_k127_6166427_2 Tetratricopeptide repeat - - - 0.00000000000000000002963 97.0
CH2_k127_6173372_0 Sulfate transporter K03321 - - 7.809e-226 712.0
CH2_k127_6173372_1 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 586.0
CH2_k127_6173372_2 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002497 504.0
CH2_k127_6173372_3 glutamate dehydrogenase K15371 - 1.4.1.2 0.00000000000000000000000000000000000000000000000000000000000007778 218.0
CH2_k127_6173372_4 - - - - 0.0000000000000000000000000000000000000000002788 164.0
CH2_k127_6173372_5 Peptidase C13 family - - - 0.000000008316 59.0
CH2_k127_6187168_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000522 142.0
CH2_k127_6195916_0 Serine dehydratase K01752 - 4.3.1.17 2.478e-269 832.0
CH2_k127_6195916_1 Lipoxygenase - - - 5.566e-219 701.0
CH2_k127_6195916_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 302.0
CH2_k127_6195916_3 thiol-disulfide isomerase and - - - 0.000000000000129 73.0
CH2_k127_6204667_0 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 341.0
CH2_k127_6204667_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 310.0
CH2_k127_6204667_2 Belongs to the UPF0758 family K03630 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000007448 248.0
CH2_k127_6204667_3 EVE domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000001873 221.0
CH2_k127_6204667_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000003416 209.0
CH2_k127_6204667_5 thiosulfate sulfurtransferase activity - - - 0.0000000000000000000000000000000000000000000000000002007 192.0
CH2_k127_6204667_6 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000002258 90.0
CH2_k127_6204667_7 TIGRFAM TIGR02449 family protein K09892 - - 0.00000000002045 64.0
CH2_k127_6204667_8 - - - - 0.00002046 53.0
CH2_k127_6226169_0 E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate K00164 - 1.2.4.2 0.0 1350.0
CH2_k127_6226169_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 392.0
CH2_k127_6226169_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000001738 97.0
CH2_k127_6246591_0 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000569 94.0
CH2_k127_6251969_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 4.693e-216 684.0
CH2_k127_6251969_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000002806 221.0
CH2_k127_6251969_2 Adenylylsulphate kinase K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000001978 148.0
CH2_k127_6272667_0 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 450.0
CH2_k127_6272667_1 Histidine kinase K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 439.0
CH2_k127_6303841_0 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 522.0
CH2_k127_6303841_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002161 237.0
CH2_k127_6303841_2 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000001073 179.0
CH2_k127_6303841_3 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000003723 147.0
CH2_k127_6303927_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 314.0
CH2_k127_6303927_1 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 304.0
CH2_k127_6303927_2 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001044 278.0
CH2_k127_6312178_0 acetyl-coa hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 520.0
CH2_k127_6312178_1 transcriptional regulator K22105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003137 257.0
CH2_k127_6313623_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 314.0
CH2_k127_6313623_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000002686 153.0
CH2_k127_6329645_0 Putative Na+/H+ antiporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 387.0
CH2_k127_6329645_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003436 260.0
CH2_k127_6341179_0 CBS domain - - - 0.000000000000000000000000000000000000000000000002418 177.0
CH2_k127_6341179_1 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.00000000000000000000000000000000000000000000001289 181.0
CH2_k127_6341179_2 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000006018 156.0
CH2_k127_6341179_3 transcriptional K03892 - - 0.000000000000000000000000000000006399 134.0
CH2_k127_6341179_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000158 108.0
CH2_k127_6379756_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000002467 250.0
CH2_k127_6379756_1 Protein of unknown function (DUF3224) - - - 0.00000000000000000000000000000000000000001407 158.0
CH2_k127_6384227_0 IG-like fold at C-terminal of FixG, putative oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 616.0
CH2_k127_6384227_1 COG2217 Cation transport ATPase K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 557.0
CH2_k127_6384227_2 FixH K09926 - - 0.0000000000000005735 87.0
CH2_k127_6426109_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 394.0
CH2_k127_6426109_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 319.0
CH2_k127_6426109_2 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000003081 207.0
CH2_k127_6426109_3 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000002204 162.0
CH2_k127_6426109_4 ACR protein K07040 - - 0.0000000000000000005572 90.0
CH2_k127_6459850_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 2.391e-230 719.0
CH2_k127_6459850_1 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000000000000000000002949 148.0
CH2_k127_6459850_2 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.000000000000000000000002618 103.0
CH2_k127_6470287_0 ABC-type sulfate transport system, periplasmic component K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 497.0
CH2_k127_6470287_1 ABC-type sulfate transport system permease component K02046 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001831 285.0
CH2_k127_6470287_2 Phosphate-selective porin O and P K07221 - - 0.0000000000005527 68.0
CH2_k127_6470543_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 467.0
CH2_k127_6470543_1 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 316.0
CH2_k127_6470543_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 295.0
CH2_k127_6505101_0 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002313 271.0
CH2_k127_6505101_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000001638 146.0
CH2_k127_6505101_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000001459 62.0
CH2_k127_656173_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1382.0
CH2_k127_656173_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 6.065e-224 696.0
CH2_k127_6577399_0 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 343.0
CH2_k127_6577399_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 314.0
CH2_k127_6577399_2 alpha-ribazole phosphatase activity K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000009346 246.0
CH2_k127_6577399_3 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000001285 131.0
CH2_k127_6577399_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000002627 79.0
CH2_k127_6577399_5 Putative restriction endonuclease - - - 0.000000003487 59.0
CH2_k127_6577399_6 Oxidoreductase - - - 0.0000004024 52.0
CH2_k127_661671_0 Y_Y_Y domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 453.0
CH2_k127_661671_1 HD domain - - - 0.000000000000000000000000000000001285 131.0
CH2_k127_6626954_0 Acetyl-CoA dehydrogenase C-terminal like - - - 1.641e-221 709.0
CH2_k127_6626954_1 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009387 263.0
CH2_k127_6626954_2 domain, Protein - - - 0.000000000003047 70.0
CH2_k127_6653991_0 Two component transcriptional regulator, winged helix family K02483,K07659 - - 0.000000000000000000000000000000000000000000000000000000000005675 217.0
CH2_k127_6653991_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000002553 164.0
CH2_k127_6653991_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000001114 154.0
CH2_k127_6653991_3 Transport permease protein - - - 0.0000000000000000000000000000006127 127.0
CH2_k127_6653991_4 phosphorelay signal transduction system - - - 0.0000000000001236 80.0
CH2_k127_6675542_0 also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity K01659 - 2.3.3.5 1.478e-203 638.0
CH2_k127_6675542_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 576.0
CH2_k127_6675542_2 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 519.0
CH2_k127_6675542_3 - - - - 0.00000000001468 72.0
CH2_k127_6678202_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 501.0
CH2_k127_6678202_1 glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000001714 263.0
CH2_k127_6678202_2 Low affinity iron permease - - - 0.00000000000000000000000000000000000000000003081 168.0
CH2_k127_6678202_3 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000002071 143.0
CH2_k127_6685209_0 FG-GAP repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000002096 248.0
CH2_k127_6685209_1 Nucleoside triphosphate K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000009955 189.0
CH2_k127_6686411_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 9.351e-240 757.0
CH2_k127_6686411_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 461.0
CH2_k127_6686411_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000002635 169.0
CH2_k127_6686411_3 Tetratricopeptide repeat - - - 0.000000000000000000000013 115.0
CH2_k127_6691972_0 nucleotidase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002147 283.0
CH2_k127_6691972_1 ADP-ribose diphosphatase K08312 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002422 265.0
CH2_k127_6691972_2 Nucleoside triphosphate K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000009194 176.0
CH2_k127_6691972_3 Evidence 5 No homology to any previously reported sequences - - - 0.00001456 57.0
CH2_k127_6717459_0 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03828 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007576 248.0
CH2_k127_6717459_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000844 76.0
CH2_k127_6719597_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 9.549e-206 650.0
CH2_k127_6719597_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 312.0
CH2_k127_6732830_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 4.576e-270 847.0
CH2_k127_6732830_1 Belongs to the RtcB family K14415 GO:0003674,GO:0003824,GO:0003909,GO:0005488,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0030145,GO:0033554,GO:0034641,GO:0042245,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:0140098,GO:1901360 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 599.0
CH2_k127_6732830_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 334.0
CH2_k127_6732830_3 lipocalin K03098 - - 0.0000000000000000000000000000000000000000000000000000000000634 209.0
CH2_k127_6732830_4 Belongs to the peptidase S8 family K13735,K20276,K21449 - - 0.000000989 55.0
CH2_k127_6735931_0 heptosyltransferase K12982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006868 382.0
CH2_k127_6735931_1 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.00000000000000000000000000000000000000000000001026 180.0
CH2_k127_6735931_2 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.000000000000000000000000001658 113.0
CH2_k127_676233_0 aminopeptidase K01263 - 3.4.11.14 2.834e-217 700.0
CH2_k127_676233_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 593.0
CH2_k127_676233_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 376.0
CH2_k127_676233_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 364.0
CH2_k127_676233_4 Zn-dependent hydrolases including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 350.0
CH2_k127_676233_5 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 319.0
CH2_k127_676311_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 6.479e-212 670.0
CH2_k127_676311_1 Trypsin-like serine protease K01337 - 3.4.21.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007506 312.0
CH2_k127_676311_2 Cardiolipin synthase - - - 0.000000000000000000000000000000003051 137.0
CH2_k127_676311_3 phosphoglycerate mutase - - - 0.0000000000000000000000000001788 124.0
CH2_k127_676311_4 Belongs to the UPF0312 family - - - 0.0000000000000000000000001109 114.0
CH2_k127_6780113_0 alpha-glucosidase K01187 - 3.2.1.20 2.821e-271 842.0
CH2_k127_6780113_1 cyclomaltodextrin glucanotransferase K00701 - 2.4.1.19 1.436e-228 721.0
CH2_k127_6780113_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 3.959e-220 696.0
CH2_k127_6780113_3 Major Facilitator K16211 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 599.0
CH2_k127_6780113_4 - - - - 0.00000000000005072 72.0
CH2_k127_6786409_0 Belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 368.0
CH2_k127_6786409_1 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001213 271.0
CH2_k127_6786409_2 Putative DNA-binding domain K09929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009859 253.0
CH2_k127_6786409_3 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000004481 233.0
CH2_k127_6786409_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000001495 226.0
CH2_k127_6786409_5 Putative adhesin - - - 0.000000000000000000000000000000000000000000000000005039 193.0
CH2_k127_6786409_6 - - - - 0.0000000000000000000000000009376 116.0
CH2_k127_6820517_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 425.0
CH2_k127_6820517_1 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000000000000000008958 224.0
CH2_k127_683196_0 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 353.0
CH2_k127_683196_1 Antitoxin component of a toxin-antitoxin (TA) module K19159 - - 0.0000000000000003667 78.0
CH2_k127_685798_0 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 406.0
CH2_k127_6859211_0 Histidine biosynthesis bifunctional protein HisB K01089 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 511.0
CH2_k127_6859211_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 505.0
CH2_k127_6859211_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 372.0
CH2_k127_6859211_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 341.0
CH2_k127_6859211_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000001556 201.0
CH2_k127_6859211_5 protein, YerC YecD - - - 0.00000000461 58.0
CH2_k127_6904670_0 cellulose binding - - - 0.000000000000000000000000000003193 121.0
CH2_k127_6904670_1 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000005743 118.0
CH2_k127_6924900_0 Catalyzes the formation of 2-oxoglutarate from isocitrate K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 543.0
CH2_k127_6924900_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000006547 214.0
CH2_k127_6924900_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000003371 108.0
CH2_k127_6924900_3 Part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.000000000000000003844 84.0
CH2_k127_6929554_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 319.0
CH2_k127_6929554_1 - - - - 0.0000000000000000000006325 100.0
CH2_k127_6953006_0 TonB dependent receptor K02014 - - 1.298e-291 910.0
CH2_k127_6953006_1 Dipeptidyl carboxypeptidase K01284 - 3.4.15.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001631 274.0
CH2_k127_6955982_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 426.0
CH2_k127_6955982_1 May be involved in recombination K03554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 336.0
CH2_k127_6955982_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 327.0
CH2_k127_6955982_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 293.0
CH2_k127_6955982_4 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000000000000000000000000006225 213.0
CH2_k127_6955982_5 Protein of unknown function (DUF465) - - - 0.00000000000000001044 85.0
CH2_k127_6955982_6 Multicopper oxidase K22350 - 1.16.3.3 0.000001428 55.0
CH2_k127_6959183_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000004001 193.0
CH2_k127_6959183_1 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000005198 111.0
CH2_k127_6959183_2 PFAM YcfA-like protein K07339 - - 0.000000000000000000000005083 105.0
CH2_k127_6959183_3 Zinc-binding dehydrogenase - - - 0.00000000002218 69.0
CH2_k127_6966589_0 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 440.0
CH2_k127_6966589_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005841 252.0
CH2_k127_6966589_2 Protein of unknown function (DUF1800) - - - 0.00000004397 59.0
CH2_k127_6967016_0 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000001325 217.0
CH2_k127_6967016_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000003623 201.0
CH2_k127_6983830_0 FtsX-like permease family K02004 - - 3.125e-274 855.0
CH2_k127_6983830_1 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000004621 143.0
CH2_k127_6984864_0 Conserved repeat domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 352.0
CH2_k127_6984864_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000962 223.0
CH2_k127_6984864_2 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000003013 60.0
CH2_k127_6984864_3 Fungalysin/Thermolysin Propeptide Motif - - - 0.0000008214 53.0
CH2_k127_6984864_4 Protein of unknown function (DUF2384) - - - 0.0001032 45.0
CH2_k127_6991391_0 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 449.0
CH2_k127_6991391_1 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000001089 121.0
CH2_k127_6991391_2 Glycosyl transferases group 1 - - - 0.000000000001193 77.0
CH2_k127_7009684_0 Protein tyrosine kinase K11912 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000005743 259.0
CH2_k127_7009684_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000007154 223.0
CH2_k127_7009684_2 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000002589 180.0
CH2_k127_7009684_3 long-chain fatty acid transporting porin activity K06076 - - 0.0001254 46.0
CH2_k127_7009684_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0006524 42.0
CH2_k127_7010234_0 Peptide synthase K22319 - 6.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 588.0
CH2_k127_7010234_1 Amidohydrolase family K01485 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050228,GO:0050279 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 422.0
CH2_k127_7010234_2 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 379.0
CH2_k127_7010234_3 3-Beta hydroxysteroid dehydrogenase isomerase K21271,K22320 - 1.1.1.394,1.1.1.412 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 376.0
CH2_k127_7010234_4 Alpha beta K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 340.0
CH2_k127_7010234_5 Membrane protein required for beta-lactamase induction K03807 - - 0.000000000000000000000000000000000000000000000000000000000000000000008343 244.0
CH2_k127_7010234_6 - - - - 0.00000000000000000000000000000000000000000000000756 177.0
CH2_k127_7010234_7 - - - - 0.00000000000000000000000000001315 130.0
CH2_k127_7010234_8 - - - - 0.0000000003962 66.0
CH2_k127_7041326_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K01876 - 6.1.1.12 4.273e-318 980.0
CH2_k127_7041326_1 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 288.0
CH2_k127_7041326_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000003261 163.0
CH2_k127_7041326_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000127 167.0
CH2_k127_7041326_4 FG-GAP repeat - - - 0.0000000000000000000001439 109.0
CH2_k127_7041326_5 SpoVT / AbrB like domain - - - 0.000000000000000001419 88.0
CH2_k127_7051221_0 cAMP biosynthetic process K12132 - 2.7.11.1 0.00000000000000000000000000000000002042 147.0
CH2_k127_7071477_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002357 280.0
CH2_k127_7071477_1 - - - - 0.00000000000000000000000004851 113.0
CH2_k127_7071477_2 ABC transporter, ATP-binding protein K01990 - - 0.00002135 48.0
CH2_k127_7083650_0 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 338.0
CH2_k127_7083650_1 homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000009 108.0
CH2_k127_7083650_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00002038 50.0
CH2_k127_709583_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004492 290.0
CH2_k127_709583_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007945 261.0
CH2_k127_709583_2 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.0000000000000000000000000000000000000000000000000000000000000001422 228.0
CH2_k127_709583_3 Low molecular weight phosphotyrosine protein phosphatase - - - 0.0000000000000000000000000000000000000000000000000000003484 195.0
CH2_k127_709583_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000401 124.0
CH2_k127_709583_5 - - - - 0.00000000000005652 83.0
CH2_k127_71460_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.625e-221 693.0
CH2_k127_71460_1 Dual specificity phosphatase, catalytic domain - - - 0.000000000000000000000000000000000000004176 154.0
CH2_k127_71460_2 - - - - 0.0000000001825 68.0
CH2_k127_7154968_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 376.0
CH2_k127_7154968_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000004742 258.0
CH2_k127_7154968_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000006092 151.0
CH2_k127_7160204_0 Peptidase family M28 K05994 - 3.4.11.10 7.231e-263 830.0
CH2_k127_7160204_1 Zinc metalloprotease (Elastase) K01399,K08604 - 3.4.24.25,3.4.24.26 0.00000000000000000000000000000000005336 134.0
CH2_k127_7172705_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 453.0
CH2_k127_7172705_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 408.0
CH2_k127_7182517_0 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 477.0
CH2_k127_7182517_1 peptidase - - - 0.0003485 46.0
CH2_k127_718981_0 Helicase K03578 - 3.6.4.13 0.0 1311.0
CH2_k127_718981_1 S1/P1 Nuclease K05986 - 3.1.30.1 0.0000000000000000000000000000000000000000000000000000000000006396 221.0
CH2_k127_7190830_0 transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 382.0
CH2_k127_7190830_1 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 299.0
CH2_k127_7190830_2 transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000002284 229.0
CH2_k127_7191306_0 - - - - 6.752e-206 659.0
CH2_k127_7191306_1 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 437.0
CH2_k127_7236792_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 449.0
CH2_k127_7236792_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 372.0
CH2_k127_7236792_2 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 369.0
CH2_k127_7236792_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 367.0
CH2_k127_7236792_4 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000846 302.0
CH2_k127_7236792_5 ECF sigma factor - - - 0.000000000000000000000000000006486 129.0
CH2_k127_7236792_6 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000001654 109.0
CH2_k127_7236792_7 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.000000000000000004156 94.0
CH2_k127_7270080_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.126e-241 754.0
CH2_k127_7270080_1 Protein of unknown function (DUF455) K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 294.0
CH2_k127_7270080_2 membrane protein, required for colicin V production K03558 - - 0.00000000000000000000000000004168 120.0
CH2_k127_7270080_3 Subtilase family - - - 0.0009857 51.0
CH2_k127_7273481_0 Integrase core domain - - - 2.536e-256 798.0
CH2_k127_7273481_1 IstB-like ATP binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 345.0
CH2_k127_7273481_2 Ribonuclease - - - 0.000001772 52.0
CH2_k127_7274176_0 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 335.0
CH2_k127_7274176_1 Fumarate reductase flavoprotein C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003751 243.0
CH2_k127_7274176_2 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000000000000000003137 236.0
CH2_k127_7274176_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001016 234.0
CH2_k127_7274176_4 - - - - 0.000000000000000000001133 101.0
CH2_k127_7274176_5 Homeodomain-like domain - - - 0.0000002803 58.0
CH2_k127_7277994_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 346.0
CH2_k127_7277994_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000003138 213.0
CH2_k127_7277994_2 type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000003631 169.0
CH2_k127_7277994_3 protein conserved in bacteria - - - 0.000000000000000000000000000009507 126.0
CH2_k127_7277994_4 protein conserved in bacteria K15539 - - 0.0000000000000000000001476 111.0
CH2_k127_7285705_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 563.0
CH2_k127_7285705_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 299.0
CH2_k127_7285705_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 299.0
CH2_k127_7285705_3 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000001579 228.0
CH2_k127_7285705_4 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000003642 199.0
CH2_k127_7285705_5 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000004414 156.0
CH2_k127_7285705_6 integral membrane protein K02221 - - 0.000000000000000000000000000000003676 138.0
CH2_k127_7285705_8 Phage-related protein - - - 0.0000002753 52.0
CH2_k127_7292274_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 8.361e-253 786.0
CH2_k127_7292274_1 helix_turn_helix, Lux Regulon K11618 - - 0.000000000000000000000000000000000000000000000001021 183.0
CH2_k127_7292274_2 Histidine kinase - - - 0.000000000000000000000000000000000004569 154.0
CH2_k127_7292274_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000478 49.0
CH2_k127_731721_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 8.695e-309 951.0
CH2_k127_731721_1 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 447.0
CH2_k127_731721_2 cytochrome c oxidase assembly protein K02258 - - 0.00000000000000000000000000000000001653 143.0
CH2_k127_7325178_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005081 280.0
CH2_k127_7325178_1 mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth K15738 - - 0.0000000000000000000000000000000001979 141.0
CH2_k127_7347260_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 364.0
CH2_k127_7347260_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000001293 211.0
CH2_k127_7347260_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000000000000000000009791 172.0
CH2_k127_7355015_0 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000000000000000000000000003916 207.0
CH2_k127_7371281_0 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 382.0
CH2_k127_7371281_1 molybdopterin biosynthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000256 266.0
CH2_k127_7371281_2 protein conserved in bacteria K09948 - - 0.000000000000000000000000000003371 123.0
CH2_k127_7371281_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000006247 53.0
CH2_k127_7386300_0 ATPase family associated with various cellular activities (AAA) - - - 2.146e-201 643.0
CH2_k127_7386300_1 Domain of unknown function (DUF4331) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 560.0
CH2_k127_7386300_2 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000000000000000005283 192.0
CH2_k127_7386300_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000003032 179.0
CH2_k127_7409228_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 608.0
CH2_k127_7409228_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008874 275.0
CH2_k127_7409228_2 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.00000000000000000000000000000004888 125.0
CH2_k127_7409505_0 ankyrin repeat K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 356.0
CH2_k127_7409505_1 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000001532 199.0
CH2_k127_7415480_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.945e-209 655.0
CH2_k127_7415480_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 403.0
CH2_k127_7415480_10 Esterase, PHB depolymerase family - - - 0.0007921 51.0
CH2_k127_7415480_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000006395 183.0
CH2_k127_7415480_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000002299 171.0
CH2_k127_7415480_4 FHA domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000003286 168.0
CH2_k127_7415480_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000001093 129.0
CH2_k127_7415480_6 membrane - - - 0.0000000000000000000000000000000368 129.0
CH2_k127_7415480_7 cyclic nucleotide-binding K10914 - - 0.000000000000000000001188 105.0
CH2_k127_7415480_8 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000000000001826 96.0
CH2_k127_7415480_9 ATP synthase I chain - - - 0.000000000000121 76.0
CH2_k127_7479556_0 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000000001167 207.0
CH2_k127_7479556_1 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000003124 126.0
CH2_k127_7479556_2 Cytochrome oxidase maturation protein cbb3-type - - - 0.000000001752 59.0
CH2_k127_7489936_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 295.0
CH2_k127_7489936_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000000000005722 220.0
CH2_k127_7489936_2 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000004449 205.0
CH2_k127_7489936_3 PA domain - - - 0.0000002116 58.0
CH2_k127_7489936_4 Protein of unknown function (DUF3293) - - - 0.000004502 56.0
CH2_k127_7497932_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 400.0
CH2_k127_7497932_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000002372 171.0
CH2_k127_7517565_0 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 493.0
CH2_k127_7517565_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 483.0
CH2_k127_7517565_2 Domain of unknown function (DUF4350) - - - 0.000000000000000000000000000000000000000000000003841 186.0
CH2_k127_7517565_3 aminopeptidase N K01256 - 3.4.11.2 0.000000000000003649 79.0
CH2_k127_753730_0 PFAM Transposase DDE domain - - - 1.362e-256 797.0
CH2_k127_753730_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 327.0
CH2_k127_753730_2 Protein of unknown function (DUF2695) - - - 0.000000000000005557 78.0
CH2_k127_753730_3 - - - - 0.0000007885 61.0
CH2_k127_7550722_0 Acylates the intermediate (KDO)2-lipid IVA to form (KDO)2-(lauroyl)-lipid IVA K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002354 283.0
CH2_k127_7550722_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000002691 218.0
CH2_k127_7551781_0 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 586.0
CH2_k127_7551781_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 532.0
CH2_k127_7551781_2 Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate K00452 - 1.13.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 306.0
CH2_k127_7560288_0 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 353.0
CH2_k127_7560288_1 - - - - 0.00000000000000000000001377 111.0
CH2_k127_7572661_0 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000002539 212.0
CH2_k127_7572661_1 Protein of unknown function (DUF3106) - - - 0.00000000000000000003702 98.0
CH2_k127_7572999_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 395.0
CH2_k127_7572999_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 345.0
CH2_k127_7572999_2 Biopolymer K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009176 248.0
CH2_k127_7572999_3 Lactoylglutathione lyase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000001543 238.0
CH2_k127_7572999_4 Biopolymer K03559 - - 0.00000000000000000000000000000000000001984 151.0
CH2_k127_7584463_0 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000009492 91.0
CH2_k127_7585031_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 505.0
CH2_k127_7585031_1 membrane-bound metal-dependent K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 317.0
CH2_k127_7585031_2 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000002922 225.0
CH2_k127_7585031_3 Putative metallopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000007766 238.0
CH2_k127_7596516_0 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 441.0
CH2_k127_7596516_1 Highly conserved protein containing a thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 344.0
CH2_k127_7596516_2 6-phosphogluconolactonase activity - - - 0.000000000000000000000001601 117.0
CH2_k127_7599180_0 hydrolase of the alpha beta-hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 389.0
CH2_k127_7599180_1 SERine Proteinase INhibitors K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006915 267.0
CH2_k127_7599180_2 Acyl carrier protein phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000006434 214.0
CH2_k127_7599180_3 Methyltransferase FkbM domain - - - 0.000000000000000709 87.0
CH2_k127_7606475_0 beta-lactamase K01467 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 406.0
CH2_k127_7607243_0 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000009651 221.0
CH2_k127_7607243_1 Major Facilitator Superfamily K03301 - - 0.000000000000000000000000000000000000000000000003744 180.0
CH2_k127_7624451_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1506.0
CH2_k127_7624451_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 516.0
CH2_k127_7624451_2 Restriction endonuclease K07448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 367.0
CH2_k127_7635812_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 497.0
CH2_k127_7635812_1 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 324.0
CH2_k127_7635812_2 Y_Y_Y domain - - - 0.0000000000000002502 91.0
CH2_k127_7639135_0 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 372.0
CH2_k127_7639135_1 membrane protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002639 236.0
CH2_k127_7639135_2 dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000008849 179.0
CH2_k127_7639135_3 - - - - 0.0000000000000000000000000000000000000001678 163.0
CH2_k127_7639135_4 membrane protein domain - - - 0.00000000000000000000000001078 115.0
CH2_k127_7642897_0 - - - - 0.00000000000000000000000000000000000000000000000000000007 213.0
CH2_k127_7642897_1 - - - - 0.000000007223 59.0
CH2_k127_7642897_2 COG3344 Retron-type reverse transcriptase - - - 0.000000274 56.0
CH2_k127_7642897_3 Membrane protease subunits, stomatin prohibitin homologs - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000009652 51.0
CH2_k127_7642897_4 Membrane protease subunits, stomatin prohibitin homologs - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00003331 46.0
CH2_k127_7645522_0 Molecular chaperone. Has ATPase activity K04079 - - 4.105e-231 730.0
CH2_k127_7645522_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000009476 119.0
CH2_k127_7652826_0 - - - - 0.0000000000000000000000000000000000001762 158.0
CH2_k127_7652826_1 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.000000000000000000000005512 120.0
CH2_k127_7652826_2 - - - - 0.000000000000000002348 101.0
CH2_k127_7680536_0 Recombination factor protein RarA K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 612.0
CH2_k127_7680536_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000001433 192.0
CH2_k127_7680536_2 - - - - 0.00000000000000000000000000000000000006013 149.0
CH2_k127_7680536_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000003062 87.0
CH2_k127_7695119_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1024.0
CH2_k127_7695119_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 285.0
CH2_k127_7695119_2 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000001194 202.0
CH2_k127_7699377_0 methyl-accepting chemotaxis protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 411.0
CH2_k127_7699377_1 Anti-sigma-factor antagonist K04749 - - 0.00000000000000000000000000002707 119.0
CH2_k127_7699377_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000003902 110.0
CH2_k127_7699377_3 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000001987 105.0
CH2_k127_7703540_0 ATP-NAD kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008323 280.0
CH2_k127_7703540_1 SPFH domain / Band 7 family - - - 0.0000000000000000000000000000007002 130.0
CH2_k127_7703540_2 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000002234 88.0
CH2_k127_7706099_0 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 314.0
CH2_k127_7706099_1 PFAM peptidase T2 asparaginase 2 K01424,K13051 - 3.4.19.5,3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002445 263.0
CH2_k127_7706099_2 transferase K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000005392 188.0
CH2_k127_7706099_3 periplasmic ligand-binding sensor domain - - - 0.000000000000893 72.0
CH2_k127_7706099_4 - - - - 0.0000000001517 67.0
CH2_k127_7706099_5 diguanylate cyclase - - - 0.000000002587 66.0
CH2_k127_7706099_6 - - - - 0.0000008154 56.0
CH2_k127_7715661_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 5.444e-222 693.0
CH2_k127_7715661_1 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009593 442.0
CH2_k127_7715661_2 Peptidase dimerisation domain K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 444.0
CH2_k127_7715661_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003414 288.0
CH2_k127_7715661_4 DNA-templated transcription, initiation K02405 - - 0.000000000000000000000000000000000000000000000000000000005363 204.0
CH2_k127_7715661_5 - - - - 0.000000000002716 76.0
CH2_k127_7721866_0 abc transporter atp-binding protein K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009505 560.0
CH2_k127_7721866_1 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000003161 205.0
CH2_k127_7721866_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000005016 173.0
CH2_k127_7721866_3 Large exoproteins involved in heme utilization or adhesion - - - 0.000000000000000000000000000002379 138.0
CH2_k127_7721866_4 - - - - 0.000000000000000000001091 106.0
CH2_k127_7730042_0 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair K03580 - - 1.228e-317 995.0
CH2_k127_7730042_1 Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid K00486 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009058,GO:0016491,GO:0019748,GO:0044550,GO:0055114 1.14.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 522.0
CH2_k127_7730042_2 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 GO:0003674,GO:0003824,GO:0004721,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 419.0
CH2_k127_7730042_3 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 422.0
CH2_k127_7730042_4 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000000000000009548 181.0
CH2_k127_7730042_5 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000001257 121.0
CH2_k127_7730042_6 conserved small protein - - - 0.00000000008998 67.0
CH2_k127_7765534_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 1.996e-263 825.0
CH2_k127_7765534_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 563.0
CH2_k127_7765534_2 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 295.0
CH2_k127_7765534_3 NADH ubiquinone oxidoreductase subunit K00342 - 1.6.5.3 0.00000000008004 63.0
CH2_k127_7766830_0 gtp-binding protein K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 425.0
CH2_k127_7766830_1 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 333.0
CH2_k127_7766830_2 Protein of unknown function (DUF3011) - - - 0.000000000000000000000000000000000000000000000000005813 196.0
CH2_k127_7798125_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 559.0
CH2_k127_7798125_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 414.0
CH2_k127_7798125_2 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 381.0
CH2_k127_7798125_3 fumarylacetoacetate hydrolase K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 285.0
CH2_k127_7798125_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000003547 163.0
CH2_k127_7798125_5 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000235 156.0
CH2_k127_7808205_0 Glycosyl transferase K20444 - - 4.741e-267 851.0
CH2_k127_7812448_0 Prolyl oligopeptidase K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 520.0
CH2_k127_7812448_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 350.0
CH2_k127_7812448_2 Alkylphosphonate utilization operon protein PhnA K06193 - - 0.0000000000000000000000000000000000000001278 155.0
CH2_k127_7836554_0 small GTP-binding protein - - - 0.0000000000000000000000000000000000000000000002676 174.0
CH2_k127_7836554_1 Roadblock/LC7 domain K07131 - - 0.000000000000000000001347 101.0
CH2_k127_7836554_2 - - - - 0.0002257 53.0
CH2_k127_7840024_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 500.0
CH2_k127_7840024_1 Methylates ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 362.0
CH2_k127_7840024_2 Protein of unknown function (DUF3426) - - - 0.00000000000000000000000000000000000000000000000000000000366 208.0
CH2_k127_7840024_3 - - - - 0.0000000000000000000000000000000000000000001615 169.0
CH2_k127_7840024_4 cell shape determination - - - 0.0000000000000000000000000000000000275 141.0
CH2_k127_7840576_0 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 606.0
CH2_k127_7840576_1 fad dependent oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 326.0
CH2_k127_7840576_2 Multidrug ABC transporter ATP-binding protein K01990 - - 0.0000000000000000000000000007829 118.0
CH2_k127_7853917_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 327.0
CH2_k127_7853917_1 Outer membrane receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009139 278.0
CH2_k127_7853917_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000001676 153.0
CH2_k127_7853917_3 helix_turn_helix, arabinose operon control protein - - - 0.000000005899 65.0
CH2_k127_7909963_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 6.069e-236 739.0
CH2_k127_7909963_1 cystathionine K01758 - 4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 467.0
CH2_k127_7909963_2 glutathione s-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000001311 254.0
CH2_k127_7944286_0 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000001771 168.0
CH2_k127_7944286_1 peptidyl-prolyl cis-trans isomerase activity K03769,K03770 - 5.2.1.8 0.00000000000000000005499 102.0
CH2_k127_7949194_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 537.0
CH2_k127_7949194_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000009594 228.0
CH2_k127_7949194_2 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000003606 213.0
CH2_k127_7949194_3 - - - - 0.000000000000000000000000000000000000000000000000008299 202.0
CH2_k127_7949194_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000001591 164.0
CH2_k127_7949194_5 Oligoketide cyclase - - - 0.00000000000000000000000000000000000000009435 163.0
CH2_k127_7949194_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000006068 120.0
CH2_k127_7949194_7 RnfH family Ubiquitin K09801 - - 0.00000000000000003682 86.0
CH2_k127_7953814_0 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000002493 230.0
CH2_k127_7980742_0 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 299.0
CH2_k127_7980742_1 DNA mismatch repair protein MutT - - - 0.000000000000000000000000000000000000000000008879 166.0
CH2_k127_7980742_2 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.00000000000000000000002226 110.0
CH2_k127_7980742_3 Winged helix-turn helix - - - 0.000003549 49.0
CH2_k127_7993222_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016150,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 6.817e-278 867.0
CH2_k127_7993222_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000007425 228.0
CH2_k127_7993222_2 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000001311 134.0
CH2_k127_8034716_0 Ferrous iron transport protein B K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 555.0
CH2_k127_8034716_1 ferrous iron transport protein K04758 - - 0.000000000000000007295 84.0
CH2_k127_8037069_0 Belongs to the UPF0061 (SELO) family - - - 9.701e-205 650.0
CH2_k127_8037069_1 peptidase - - - 0.0000000000000000000000000000000000000000000000000001657 187.0
CH2_k127_8037069_2 Histidine kinase - - - 0.00000000000000000000000000000000000000001669 158.0
CH2_k127_8047151_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 443.0
CH2_k127_8047151_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006891 430.0
CH2_k127_8047151_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 374.0
CH2_k127_8047151_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 312.0
CH2_k127_8047151_4 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000002466 137.0
CH2_k127_8047151_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000001504 135.0
CH2_k127_8047151_6 Protein of unknown function (DUF952) - - - 0.0000000000000000000000000065 114.0
CH2_k127_8051040_0 Transport permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 527.0
CH2_k127_8051040_1 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001321 278.0
CH2_k127_8056416_0 phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 604.0
CH2_k127_8056416_1 Zinc-uptake complex component A periplasmic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 426.0
CH2_k127_8056416_2 PFAM ABC-3 protein K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 401.0
CH2_k127_8056416_3 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000003985 216.0
CH2_k127_8056416_4 glutamate--cysteine ligase K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000002889 216.0
CH2_k127_8056416_5 Phasin protein - - - 0.0000000000000000000000123 106.0
CH2_k127_8079969_0 Transporter K03305 - - 8.101e-246 767.0
CH2_k127_8079969_1 MarR family transcriptional regulator - - - 0.000000000000000000000002731 104.0
CH2_k127_8079969_2 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.000000000000007503 74.0
CH2_k127_8096075_0 ATPase family associated with various cellular activities (AAA) - - - 1.661e-221 694.0
CH2_k127_8096075_1 thiamine-containing compound biosynthetic process K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008649 532.0
CH2_k127_8096075_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001017 280.0
CH2_k127_8106181_0 2OG-Fe(II) oxygenase superfamily K07394 - - 0.000000000000000000000000000000000000000001434 164.0
CH2_k127_8106181_1 Protein of unknown function (DUF502) - - - 0.00000000000000000000000427 105.0
CH2_k127_8106181_2 AAA domain K14680 - 6.5.1.3 0.000000000000000004433 92.0
CH2_k127_8106181_3 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair K03580 - - 0.0000000000824 64.0
CH2_k127_81148_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 531.0
CH2_k127_81148_1 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000000000000000000000000000000001197 157.0
CH2_k127_81148_2 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000000000007305 128.0
CH2_k127_81148_3 Dystroglycan-type cadherin-like domains. - - - 0.0000000000000000000000000000001018 143.0
CH2_k127_8118507_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.926e-233 737.0
CH2_k127_8118507_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 584.0
CH2_k127_8118507_2 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000001226 164.0
CH2_k127_8118507_3 AAA domain - - - 0.0000000000000000000004616 99.0
CH2_k127_8118507_4 SnoaL-like domain - - - 0.000000000000001515 84.0
CH2_k127_81286_0 MASE1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 541.0
CH2_k127_81286_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002992 252.0
CH2_k127_81286_2 secretion protein K01993 - - 0.000000000000000000000000000000000000000001289 167.0
CH2_k127_81286_3 diguanylate cyclase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000001397 167.0
CH2_k127_8136029_0 Acyl transferase domain - - - 1.745e-316 1020.0
CH2_k127_8136029_1 FabA-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 574.0
CH2_k127_81545_0 Nitrite reductase K15864 - 1.7.2.1,1.7.99.1 0.0 1039.0
CH2_k127_81545_1 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 346.0
CH2_k127_81545_2 receptor K16087 - - 0.00000000000000000000000000000000000000000000002367 181.0
CH2_k127_8163279_0 Domain of unknown function (DUF4785) - - - 0.0000000000000000000000000000000000000000000000132 184.0
CH2_k127_8163279_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000001374 120.0
CH2_k127_816963_0 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 4.233e-270 846.0
CH2_k127_816963_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000002705 207.0
CH2_k127_8179138_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000001819 263.0
CH2_k127_8179138_1 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000009272 183.0
CH2_k127_8179138_2 ECF sigma factor - - - 0.000000000000000000000000000000000009886 143.0
CH2_k127_8179138_3 pyridoxamine 5'-phosphate oxidase-related, FMN-binding - - - 0.00000000000000000000000000162 116.0
CH2_k127_8185993_0 Involved in the processing of the 5'end of 16S rRNA K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 577.0
CH2_k127_8185993_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 569.0
CH2_k127_8185993_2 abc transporter atp-binding protein K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 329.0
CH2_k127_8185993_3 abc transporter, permease K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 313.0
CH2_k127_8185993_4 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000001902 234.0
CH2_k127_8185993_5 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000009949 197.0
CH2_k127_8185993_6 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000001085 186.0
CH2_k127_8185993_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000000004024 179.0
CH2_k127_8185993_8 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000000000002787 179.0
CH2_k127_8185993_9 - - - - 0.0002445 46.0
CH2_k127_8211813_0 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 523.0
CH2_k127_8211813_1 4-phosphoerythronate dehydrogenase activity K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000614 160.0
CH2_k127_8211813_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000008299 153.0
CH2_k127_8218171_0 alginic acid biosynthetic process K01176 - 3.2.1.1 7.656e-245 779.0
CH2_k127_8218171_1 Domain of unknown function (DUF4331) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 522.0
CH2_k127_8218171_2 Transposase DDE domain group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 492.0
CH2_k127_8218171_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004224 278.0
CH2_k127_8218171_4 alpha/beta hydrolase fold - - - 0.000000000000001118 85.0
CH2_k127_8245654_0 - - - - 7.151e-198 648.0
CH2_k127_8266428_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 8.057e-281 874.0
CH2_k127_8266428_1 Protein of unknown function (DUF1501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 317.0
CH2_k127_8266428_2 Hep Hag repeat protein K21449 - - 0.000000000000000000000000000000000000000000000008387 194.0
CH2_k127_8289243_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 425.0
CH2_k127_8289243_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 GO:0003674,GO:0003824,GO:0004733,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000002348 252.0
CH2_k127_8289243_2 Two component response regulator for the phosphate regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008203 247.0
CH2_k127_8289243_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000001045 212.0
CH2_k127_8289243_4 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000001401 203.0
CH2_k127_8289243_5 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000003431 200.0
CH2_k127_8289243_6 Domain of unknown function (DUF4399) - - - 0.00000000000000000000000000000000000000000001207 164.0
CH2_k127_8289243_7 Dodecin K09165 - - 0.0000000000000000000006205 98.0
CH2_k127_8321758_0 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 390.0
CH2_k127_834883_0 Transport of potassium into the cell K03549 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 325.0
CH2_k127_834883_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000004405 264.0
CH2_k127_834883_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000004768 241.0
CH2_k127_8349147_0 Bacterial protein of unknown function (DUF885) - - - 4.072e-250 786.0
CH2_k127_8349147_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 511.0
CH2_k127_8349147_2 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 288.0
CH2_k127_8349147_3 PFAM FHA domain - - - 0.00000000000003314 79.0
CH2_k127_8349147_4 Parallel beta-helix repeats - - - 0.0005003 45.0
CH2_k127_8353747_0 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 441.0
CH2_k127_8353747_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002506 252.0
CH2_k127_8353747_2 domain, Protein K21449 - - 0.00001071 58.0
CH2_k127_8375445_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1602.0
CH2_k127_8375445_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000003301 73.0
CH2_k127_8379197_0 dna polymerase K02337 - 2.7.7.7 2.487e-274 859.0
CH2_k127_8379197_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000004568 156.0
CH2_k127_8388657_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 497.0
CH2_k127_8388657_1 Dolichol-phosphate mannosyltransferase K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 400.0
CH2_k127_8388657_2 chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 394.0
CH2_k127_8388657_3 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 355.0
CH2_k127_8388657_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 311.0
CH2_k127_8388657_5 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006578 243.0
CH2_k127_8388657_6 Protein of unknown function (DUF3379) - - - 0.0000000000000000000000000000003195 132.0
CH2_k127_8388657_7 Lipid A Biosynthesis N-terminal domain - - - 0.0000000000000000000000000001643 118.0
CH2_k127_8388657_8 Biopolymer transport protein K03559 - - 0.00000000000000001128 86.0
CH2_k127_8388657_9 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000009225 57.0
CH2_k127_8480656_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 491.0
CH2_k127_8480656_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 370.0
CH2_k127_8499830_0 cellulase activity - - - 0.0000000000000000000000007996 118.0
CH2_k127_8528185_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 5.888e-235 733.0
CH2_k127_8528185_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 447.0
CH2_k127_8528185_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000002024 116.0
CH2_k127_8528185_3 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000003117 81.0
CH2_k127_8529540_0 COG4772 Outer membrane receptor for Fe3 -dicitrate K16091 GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0008150,GO:0008324,GO:0009279,GO:0015075,GO:0015091,GO:0015318,GO:0015682,GO:0016020,GO:0019867,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030313,GO:0031975,GO:0034220,GO:0034755,GO:0044462,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0072510,GO:0072512,GO:0098655,GO:0098660,GO:0098662 - 7.758e-194 624.0
CH2_k127_8529540_1 converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA K06445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 550.0
CH2_k127_8529540_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 288.0
CH2_k127_8529540_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000008002 239.0
CH2_k127_8546290_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 469.0
CH2_k127_8546290_1 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000001595 233.0
CH2_k127_8546290_2 - - - - 0.0000000000000000000000000000000000000000007422 164.0
CH2_k127_8546290_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000009848 126.0
CH2_k127_8546290_4 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000003413 61.0
CH2_k127_8558818_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 357.0
CH2_k127_8558818_1 Exodeoxyribonuclease IX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 334.0
CH2_k127_8558818_2 nitroreductase - - - 0.00000000000000000000000000000000001072 140.0
CH2_k127_8628751_0 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 317.0
CH2_k127_8628751_1 ABC transporter - - - 0.000000000000000000000000000000001089 132.0
CH2_k127_8633978_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000001443 198.0
CH2_k127_8633978_1 Beta-ketoacyl synthase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000162 190.0
CH2_k127_8665557_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 550.0
CH2_k127_8665557_1 Belongs to the Fur family K09823 - - 0.000002738 50.0
CH2_k127_8667006_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1063.0
CH2_k127_8667006_1 Protein of unknown function (DUF4080) - - - 1.358e-200 636.0
CH2_k127_8667006_2 Oxidoreductase K06969 - 2.1.1.191 1.112e-197 623.0
CH2_k127_8667006_3 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007256 466.0
CH2_k127_8667006_4 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 394.0
CH2_k127_8667006_5 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 350.0
CH2_k127_8667006_6 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000001291 263.0
CH2_k127_8667006_8 Putative phosphatase (DUF442) - - - 0.000000000002032 75.0
CH2_k127_8667006_9 PFAM Formylglycine-generating sulfatase enzyme K20276 - - 0.000000003417 59.0
CH2_k127_869476_0 Male sterility protein - - - 3.204e-286 889.0
CH2_k127_869476_1 Bacterial transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000001197 224.0
CH2_k127_869476_2 Acyl CoA binding protein - - - 0.0000000000000000000000000000000001198 135.0
CH2_k127_869476_3 Bacterial transcriptional repressor - - - 0.00000000000006548 75.0
CH2_k127_8715576_0 Histidine Phosphotransfer domain - - - 3.063e-239 769.0
CH2_k127_8715576_1 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575,K02661 - 2.1.1.80 0.0000000000000000000000000003016 118.0
CH2_k127_8734688_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0 1417.0
CH2_k127_8734688_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 482.0
CH2_k127_8734688_2 Addiction module toxin RelE StbE family - - - 0.0000000000000000000000000000000006623 135.0
CH2_k127_8734688_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000000007342 112.0
CH2_k127_8766457_0 Belongs to the arginase family K01476 - 3.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 518.0
CH2_k127_8766457_1 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002854 267.0
CH2_k127_8766672_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000004933 246.0
CH2_k127_8781693_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 333.0
CH2_k127_8781693_1 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000202 213.0
CH2_k127_8781693_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000005806 130.0
CH2_k127_8794004_0 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000003998 172.0
CH2_k127_8794004_1 Protein of unknown function DUF58 - - - 0.00001909 53.0
CH2_k127_8805182_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 3.464e-217 681.0
CH2_k127_8805182_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 451.0
CH2_k127_8805182_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 312.0
CH2_k127_8805182_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 296.0
CH2_k127_8805182_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000006231 202.0
CH2_k127_8805182_5 Tfp pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000007697 157.0
CH2_k127_8805182_6 Belongs to the folylpolyglutamate synthase family K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.00000000000000000000000005115 109.0
CH2_k127_8809025_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 561.0
CH2_k127_8809025_1 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 308.0
CH2_k127_8809025_2 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 305.0
CH2_k127_8809025_3 Regulatory protein, FmdB family - - - 0.00000000000000000000003446 104.0
CH2_k127_8809025_4 polysaccharide deacetylase - - - 0.00000000000000000003683 94.0
CH2_k127_8809025_5 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.000001783 52.0
CH2_k127_8811196_0 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 526.0
CH2_k127_8811196_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 427.0
CH2_k127_8811196_2 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 325.0
CH2_k127_8811196_4 Pkd domain containing protein - - - 0.000000000716 71.0
CH2_k127_8811196_5 Domain of unknown function DUF11 K03634,K14166 - - 0.00005241 55.0
CH2_k127_8845857_0 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009066 541.0
CH2_k127_8845857_1 haloacid dehalogenase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 301.0
CH2_k127_8845857_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000002179 174.0
CH2_k127_8865938_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 515.0
CH2_k127_8865938_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000000005207 164.0
CH2_k127_8866420_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 488.0
CH2_k127_8866420_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 355.0
CH2_k127_8866420_2 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004549 272.0
CH2_k127_8866420_3 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000003949 198.0
CH2_k127_8866420_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000614 189.0
CH2_k127_8866420_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000019 168.0
CH2_k127_8866420_6 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000007236 132.0
CH2_k127_8890157_0 TonB-dependent Receptor Plug Domain K02014 - - 4.746e-280 878.0
CH2_k127_8890157_1 transporter - - - 3.212e-238 744.0
CH2_k127_8890157_2 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 574.0
CH2_k127_8890157_3 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 505.0
CH2_k127_8890157_4 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 431.0
CH2_k127_8890157_5 COG0591 Na proline symporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 339.0
CH2_k127_8890157_6 metallopeptidase activity - - - 0.0000000000000000000000000000000000000005736 158.0
CH2_k127_8890157_7 - - - - 0.000000000000000000000000000005988 125.0
CH2_k127_8890157_8 ThiJ/PfpI family-like - - - 0.00000000000000000000783 93.0
CH2_k127_8913317_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000002008 263.0
CH2_k127_8913317_1 transglycosylase K08307 - - 0.0000000000000000000000000000000000000000000000000504 194.0
CH2_k127_8934007_0 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001131 273.0
CH2_k127_8934007_1 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001495 226.0
CH2_k127_8950854_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.106e-264 824.0
CH2_k127_8962519_0 signal transduction histidine kinase - - - 5.266e-216 719.0
CH2_k127_8962519_1 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005989 277.0
CH2_k127_8962519_3 Gcn5-related n-acetyltransferase - - - 0.0000000000000000000000000000001545 130.0
CH2_k127_8962519_4 Protein of unknown function (DUF2782) - - - 0.000000000000000000848 91.0
CH2_k127_8964777_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 460.0
CH2_k127_8964777_1 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 316.0
CH2_k127_8964777_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000006279 203.0
CH2_k127_8964777_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000004537 115.0
CH2_k127_8964777_4 Belongs to the UPF0250 family K09158 - - 0.000000000000000004408 87.0
CH2_k127_8983992_0 Acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 565.0
CH2_k127_8983992_1 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000000000000002103 139.0
CH2_k127_8990439_0 Ribonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000131 275.0
CH2_k127_8990439_1 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.00000000000000000000000000000000000002479 165.0
CH2_k127_9022238_0 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 523.0
CH2_k127_9022238_1 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000002985 186.0
CH2_k127_9022238_2 Cysteine-rich CPXCG - - - 0.00000000000000005256 84.0
CH2_k127_9037634_0 Cysteine dioxygenase type I - - - 0.00000000000000000000000000000000000000000000000000000000000000000001394 239.0
CH2_k127_9037634_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000001646 141.0
CH2_k127_9037634_2 Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000004288 96.0
CH2_k127_9042755_0 Histidine kinase - - - 0.0000000000000000000000000000003241 125.0
CH2_k127_9042755_1 Protein of unknown function (DUF1631) - - - 0.0000000000000000003847 98.0
CH2_k127_904832_0 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005778 270.0
CH2_k127_904832_1 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001357 253.0
CH2_k127_904832_2 Domain of unknown function (DUF4166) - - - 0.000000000000000000000000000000000000000000000000000000000001511 214.0
CH2_k127_904832_3 Fungalysin metallopeptidase (M36) - - - 0.00000000000000000003891 97.0
CH2_k127_904832_4 - - - - 0.000000000000000003932 92.0
CH2_k127_9053604_0 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 492.0
CH2_k127_9053604_1 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.000000000000000000000000000000000000002406 153.0
CH2_k127_9053604_2 Male sterility protein - - - 0.000000000000000000000000000001308 121.0
CH2_k127_9066448_0 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 5.718e-246 771.0
CH2_k127_9066448_1 Two component signalling adaptor domain K06598 - - 0.00000000000000000000000000000000000000000000000003178 183.0
CH2_k127_9066448_2 COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K06597 - - 0.000000000000000000000000000000000000000472 170.0
CH2_k127_9088484_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1215.0
CH2_k127_91374_0 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000003632 214.0
CH2_k127_914779_0 Belongs to the FBPase class 1 family K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 524.0
CH2_k127_914779_1 Protein of unknown function (DUF3142) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009848 271.0
CH2_k127_914779_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000001203 226.0
CH2_k127_914779_3 Protein of unknown function (DUF4065) - - - 0.00000000000000000000000000000000000000000007637 167.0
CH2_k127_914779_4 Type IV pilus biogenesis stability protein PilW - - - 0.00000005405 59.0
CH2_k127_9168039_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 513.0
CH2_k127_9168039_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 484.0
CH2_k127_9168039_2 DNA repair photolyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007329 276.0
CH2_k127_9168039_3 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000004195 153.0
CH2_k127_9168923_0 AraC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 339.0
CH2_k127_9168923_1 PGAP1-like protein - - - 0.0000000000000000000000000000000000000008231 152.0
CH2_k127_9192957_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 4.93e-216 676.0
CH2_k127_9192957_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 458.0
CH2_k127_9192957_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000004632 117.0
CH2_k127_9203649_0 Dak2 K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 414.0
CH2_k127_9203649_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000303 248.0
CH2_k127_9203649_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000005465 224.0
CH2_k127_9203649_3 Sporulation related domain - - - 0.0000000000000000000000000000000000000000000000000000000494 203.0
CH2_k127_9203649_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000001263 143.0
CH2_k127_9203649_5 Hpt domain - - - 0.000004978 53.0
CH2_k127_9205258_0 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005633 276.0
CH2_k127_9205258_1 TIGRFAM type IV pilus modification protein PilV K02671 - - 0.000000000000000000000000003145 117.0
CH2_k127_9205258_2 Type II transport protein GspH K08084 - - 0.00000004452 61.0
CH2_k127_9205258_3 Type IV Pilus-assembly protein W K02672 - - 0.0000004134 59.0
CH2_k127_9206477_0 domain, Protein K15125 - - 0.00000001031 68.0
CH2_k127_9206477_1 Squalene-hopene cyclase N-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.000003538 56.0
CH2_k127_920852_0 FAD FMN-containing dehydrogenases K00102,K03777 - 1.1.2.4,1.1.5.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 548.0
CH2_k127_920852_1 (Lipo)protein K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 359.0
CH2_k127_920852_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 296.0
CH2_k127_920852_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000000000000002648 212.0
CH2_k127_920852_4 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000006971 157.0
CH2_k127_920852_5 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000347 149.0
CH2_k127_920852_6 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000005206 128.0
CH2_k127_920852_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000001214 89.0
CH2_k127_9226889_0 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 380.0
CH2_k127_9226889_1 Catalyzes the dephosphorylation of 2-phosphoglycolate to form glycolate and phosphate K22292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.105 0.00000000000000000000000000000000000000000000000000001358 196.0
CH2_k127_9226889_2 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000000000008754 98.0
CH2_k127_9226889_3 Phytoene synthase - - - 0.0000007793 59.0
CH2_k127_9243847_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 375.0
CH2_k127_9243847_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000001055 170.0
CH2_k127_9257427_0 FabA-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 467.0
CH2_k127_9295830_0 Large extracellular alpha-helical protein K06894 - - 0.0 1549.0
CH2_k127_9295830_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX - - - 0.000001002 60.0
CH2_k127_9298263_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 2.48e-212 662.0
CH2_k127_9298263_1 Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA K00253 - 1.3.8.4 1.163e-211 664.0
CH2_k127_9298263_2 SMART metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 385.0
CH2_k127_9340793_0 Type II secretory pathway, component HofQ K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 289.0
CH2_k127_9340793_1 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005771 247.0
CH2_k127_9340793_2 assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000000000000000001383 193.0
CH2_k127_9340793_3 pilus assembly protein pilp K02665 - - 0.000000000000000000000000000000000000000000000001035 184.0
CH2_k127_9340793_4 Pilus assembly protein K02662 - - 0.00000000000000000000000000000000000009977 143.0
CH2_k127_9345424_0 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 479.0
CH2_k127_9345424_1 recombinase activity K07450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 284.0
CH2_k127_9345424_2 Transposase, IS605 OrfB family - - - 0.00000000000000000000000000000000000000000000000000001492 195.0
CH2_k127_9356445_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 362.0
CH2_k127_9356445_1 Elongation factor P K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004662 284.0
CH2_k127_9356445_2 IMG reference gene - - - 0.0000000000000003509 87.0
CH2_k127_9356445_3 Cell Wall - - - 0.0000000004347 63.0
CH2_k127_9372209_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1038.0
CH2_k127_9372209_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009901 238.0
CH2_k127_9372209_2 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000119 211.0
CH2_k127_9374883_0 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 326.0
CH2_k127_9374883_1 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000001249 203.0
CH2_k127_9374883_2 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.0000000000000000000000000000000000000000000000001227 179.0
CH2_k127_9374883_3 Specific class of high-redox-potential 4Fe-4S ferredoxins. Functions in anaerobic electron transport in most purple and in some other photosynthetic bacteria and in at least one genus (Paracoccus) of halophilic, denitrifying bacteria - - - 0.000000000000000000000007433 106.0
CH2_k127_9374883_4 amino acid K03294 - - 0.000000001351 61.0
CH2_k127_9374883_5 PhoQ Sensor - - - 0.0001392 50.0
CH2_k127_9389029_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 540.0
CH2_k127_9389029_1 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 408.0
CH2_k127_9391181_0 converts acyl-CoA and FAD to FADH2 and delta2-enoyl-CoA K06445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 576.0
CH2_k127_9391181_1 GMC oxidoreductase K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000003542 174.0
CH2_k127_9391181_2 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000003486 157.0
CH2_k127_9450807_0 5'-nucleotidase K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 445.0
CH2_k127_9450807_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 432.0
CH2_k127_9467895_0 membrane K07148 - - 0.0000000000000000000000000000000000000000000000000003424 196.0
CH2_k127_9467895_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000006563 182.0
CH2_k127_9467895_2 Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000000000000000000002336 160.0
CH2_k127_9482905_0 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 436.0
CH2_k127_9482905_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001257 284.0
CH2_k127_9482905_2 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003298 270.0
CH2_k127_9482905_3 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000008034 161.0
CH2_k127_9482905_4 Transport permease protein K09690 - - 0.0000000000000000000000000000000002555 141.0
CH2_k127_9482905_5 - - - - 0.00000000000003115 76.0
CH2_k127_9486055_0 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 389.0
CH2_k127_9510945_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000002079 157.0
CH2_k127_9510945_1 Histidine kinase - - - 0.000119 54.0
CH2_k127_9515800_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008922 544.0
CH2_k127_9515800_1 TolQ protein K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 296.0
CH2_k127_9515800_2 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000001029 192.0
CH2_k127_9515800_3 Biopolymer transport protein K03560 - - 0.0000000000000000000000000000000000000000005058 162.0
CH2_k127_9515800_4 Acyl-CoA thioesterase K07107 - - 0.00000000000000000000000000000000003265 142.0
CH2_k127_9515800_5 Membrane protein TolA K03646 - - 0.000000000000000000000000000000001083 142.0
CH2_k127_9515800_6 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000002934 82.0
CH2_k127_9524333_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 5.901e-240 748.0
CH2_k127_9524333_1 chemotaxis protein K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 390.0
CH2_k127_9524333_2 Belongs to the prokaryotic GSH synthase family K01920 GO:0003674,GO:0003824,GO:0004363,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0019184,GO:0034641,GO:0042398,GO:0043043,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044424,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901564,GO:1901566,GO:1901576 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 381.0
CH2_k127_9524333_3 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 346.0
CH2_k127_9524333_4 tonb protein K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007332 285.0
CH2_k127_9524333_5 response regulator K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000146 236.0
CH2_k127_9524333_6 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000001363 226.0
CH2_k127_9524333_7 chemotaxis signal transduction protein K02659 - - 0.000000000000000000000000000000000000000000000000000002123 197.0
CH2_k127_9524333_8 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000001526 141.0
CH2_k127_9524333_9 Protein of unknown function (DUF3253) - - - 0.00000000000000000169 88.0
CH2_k127_9531165_0 PFAM Endonuclease Exonuclease phosphatase K07004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005314 310.0
CH2_k127_9531165_1 Phage Tail Collar Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007538 274.0
CH2_k127_9531165_2 Phage Tail Collar Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003849 273.0
CH2_k127_9531165_3 Phage Tail Collar Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004096 261.0
CH2_k127_9531165_4 Acetyltransferase (GNAT) domain - - - 0.00000000006788 66.0
CH2_k127_9541582_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 2.496e-265 820.0
CH2_k127_9541582_1 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 1.089e-261 813.0
CH2_k127_9541582_2 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 583.0
CH2_k127_9541582_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 582.0
CH2_k127_9541582_4 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 527.0
CH2_k127_9541582_5 ABC-type spermidine putrescine transport system, permease component I K11075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 477.0
CH2_k127_9541582_6 Glutamine K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 371.0
CH2_k127_9541582_7 Binding-protein-dependent transport system inner membrane component K11074 - - 0.000000000001 74.0
CH2_k127_9556931_0 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 368.0
CH2_k127_9556931_1 TonB dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 319.0
CH2_k127_9556931_2 carbonic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 291.0
CH2_k127_9573230_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 443.0
CH2_k127_9573230_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000014 299.0
CH2_k127_9573230_2 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000225 271.0
CH2_k127_9573230_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000001234 73.0
CH2_k127_957659_0 receptor K16087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 378.0
CH2_k127_957659_1 FabA-like domain - - - 0.00000000000000000000000000000000000006075 145.0
CH2_k127_957659_2 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000000000000002871 105.0
CH2_k127_9581864_0 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000002173 131.0
CH2_k127_9581864_1 polyhydroxyalkanoic acid - - - 0.000000000000000000000192 105.0
CH2_k127_9581864_2 Protein tyrosine kinase - - - 0.000000000000001298 90.0
CH2_k127_9614517_0 abc transporter atp-binding protein K06147 - - 6.228e-291 904.0
CH2_k127_9614517_1 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003255 266.0
CH2_k127_9614517_2 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000000000000000000001255 235.0
CH2_k127_9614517_3 COG0346 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000001988 216.0
CH2_k127_9614517_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000856 216.0
CH2_k127_9614517_5 - - - - 0.000000000008215 75.0
CH2_k127_9623108_0 Methyltransferase K00564 - 2.1.1.172 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 372.0
CH2_k127_9623108_1 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 282.0
CH2_k127_9623304_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 585.0
CH2_k127_9623304_1 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.00000000000000000000000000000000000000000000000000003734 199.0
CH2_k127_9623304_2 Outer membrane protein W K07275 - - 0.0000000000000000000000000000000000136 151.0
CH2_k127_9623304_3 Conserved repeat domain - - - 0.00003071 56.0
CH2_k127_9623909_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 371.0
CH2_k127_9623909_1 - - - - 0.00000000000000000000183 99.0
CH2_k127_9625319_0 Bacterial virulence factor lipase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 497.0
CH2_k127_9625319_1 glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000252 289.0
CH2_k127_9627818_0 Hydrolase CocE NonD family - - - 1.778e-253 791.0
CH2_k127_9634699_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 4.012e-217 683.0
CH2_k127_9634699_1 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000000000847 128.0
CH2_k127_9642041_0 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000151 280.0
CH2_k127_9642041_1 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000001722 195.0
CH2_k127_9642041_2 MFS transporter - - - 0.000000000000000888 81.0
CH2_k127_9648832_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 383.0
CH2_k127_9648832_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000001128 205.0
CH2_k127_9648832_2 Entericidin EcnA/B family - - - 0.0004929 49.0
CH2_k127_9687876_2 Protein of unknown function (DUF3011) - - - 0.00000000000000000000000000001205 126.0
CH2_k127_9687876_3 belongs to the thioredoxin family K00384,K03671 - 1.8.1.9 0.0000000002422 68.0
CH2_k127_9722314_0 glutamate dehydrogenase K15371 - 1.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000001055 241.0
CH2_k127_9722314_1 Protein of unknown function (DUF1631) - - - 0.0000000000000000000000000000000000000000000000000000000003454 224.0
CH2_k127_9733465_0 Belongs to the mandelate racemase muconate lactonizing enzyme family K19802 - 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 507.0
CH2_k127_9733465_1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 351.0
CH2_k127_9733465_2 protein conserved in bacteria - - - 0.000001984 53.0
CH2_k127_9739935_0 Oxidoreductase K09471 - - 1.494e-200 632.0
CH2_k127_9739935_1 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000001068 192.0
CH2_k127_9744558_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0 1080.0
CH2_k127_9744558_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 6.028e-203 641.0
CH2_k127_9744558_2 NADP transhydrogenase K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 505.0
CH2_k127_9744558_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000003163 214.0
CH2_k127_9744558_4 NADP transhydrogenase K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000005864 164.0
CH2_k127_9744558_5 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000009222 137.0
CH2_k127_9744558_6 - - - - 0.0000000000000000001312 97.0
CH2_k127_9748369_0 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001528 261.0
CH2_k127_9748369_1 membrane transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001364 240.0
CH2_k127_9752848_0 Caspase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 345.0
CH2_k127_9769507_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 6.77e-235 739.0
CH2_k127_9769507_1 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000000000001248 141.0
CH2_k127_9769507_2 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000001038 78.0
CH2_k127_9770183_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 342.0
CH2_k127_9770183_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 286.0
CH2_k127_9770183_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000004979 191.0
CH2_k127_9770183_3 Domain of unknown function (DUF4345) - - - 0.00000000000000000000003562 108.0
CH2_k127_9812135_0 protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 559.0
CH2_k127_9812135_1 protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 441.0
CH2_k127_9826786_0 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000000001009 124.0
CH2_k127_9826786_1 Type IV pilus assembly protein PilX C-term K02673 - - 0.000000000000000001322 93.0
CH2_k127_9826786_2 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 0.000000000000001152 85.0
CH2_k127_9836498_0 synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 495.0
CH2_k127_9836498_1 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 327.0
CH2_k127_984848_1 ECF sigma factor family protein - - - 0.00000000000001627 82.0
CH2_k127_984848_2 Protein tyrosine kinase - - - 0.00000007511 62.0
CH2_k127_9850001_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 577.0
CH2_k127_9850001_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006829 233.0
CH2_k127_9850001_2 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.00000000000000000000000000001228 119.0
CH2_k127_9850001_3 SUF system FeS assembly protein, NifU family K04488 - - 0.00000000000000000000004909 104.0
CH2_k127_9881772_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 369.0
CH2_k127_9881772_1 - - - - 0.00000000000000000000000000000000000000000000003105 178.0
CH2_k127_9881772_2 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.0000000006246 64.0
CH2_k127_9882023_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 6.986e-263 814.0
CH2_k127_9882023_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 364.0
CH2_k127_9882023_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000000000000027 147.0
CH2_k127_98849_0 homoserine dehydrogenase K12524 - 1.1.1.3,2.7.2.4 2.14e-263 824.0
CH2_k127_9894988_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 288.0
CH2_k127_9894988_1 PIN domain - - - 0.0000000001483 63.0
CH2_k127_9894988_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000002278 55.0
CH2_k127_9894988_3 - - - - 0.00000003227 61.0
CH2_k127_989965_0 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 495.0
CH2_k127_990055_0 Outer membrane receptor proteins mostly Fe transport K02014 - - 8.555e-293 915.0
CH2_k127_990055_1 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 291.0
CH2_k127_9906698_0 cellulose binding - - - 0.000000000000000003776 99.0
CH2_k127_9906698_1 cellulose binding - - - 0.0000000000002513 81.0
CH2_k127_9912395_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 5.162e-259 804.0
CH2_k127_9912395_1 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000002103 199.0
CH2_k127_9914529_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 610.0
CH2_k127_9914529_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 535.0
CH2_k127_9914529_2 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 469.0
CH2_k127_9914529_3 Tfp pilus assembly protein FimV K08086 - - 0.000000000000000000000000000000000000000000000000000000000000003906 231.0
CH2_k127_9930252_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 600.0
CH2_k127_9930252_1 MerR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000007031 202.0
CH2_k127_9930252_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000003565 152.0
CH2_k127_9930252_3 - - - - 0.00002314 47.0
CH2_k127_9939563_0 alpha/beta hydrolase fold K01046 - 3.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 464.0
CH2_k127_9939563_1 Protein of unknown function (DUF1800) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001816 258.0
CH2_k127_9944526_0 Outer membrane receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 449.0
CH2_k127_994510_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 413.0
CH2_k127_994510_1 Protein of unknown function (DUF1449) - - - 0.00000000000000000000000000000000000000004949 160.0
CH2_k127_994510_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000001988 83.0
CH2_k127_9970453_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 5e-324 1017.0
CH2_k127_9970453_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000009982 217.0
CH2_k127_9981612_0 dehydrogenase K00382 - 1.8.1.4 1.812e-205 645.0
CH2_k127_9981612_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000002022 102.0
CH2_k127_9990561_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 6.908e-224 709.0
CH2_k127_9990561_1 Belongs to the UbiD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 565.0
CH2_k127_9990561_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 564.0
CH2_k127_9990561_3 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000008597 156.0
CH2_k127_9990561_4 - - - - 0.000000000000000000000000000000000006653 141.0