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Overview

ID MAG00302
Name CMS1_bin.115
Sample SMP0010
Taxonomy
Kingdom Bacteria
Phylum Campylobacterota
Class Campylobacteria
Order Campylobacterales
Family Sulfurimonadaceae
Genus S145-25
Species
Assembly information
Completeness (%) 94.43
Contamination (%) 2.02
GC content (%) 53.0
N50 (bp) 34,144
Genome size (bp) 2,273,884

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2170

Gene name Description KEGG GOs EC E-value Score Sequence
CMS1_k127_1004714_0 Belongs to the 5'-nucleotidase family K01119,K17224 - 3.1.3.6,3.1.4.16 0.0 1072.0
CMS1_k127_1004714_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 4.402e-272 841.0
CMS1_k127_1004714_10 sensor protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001819 258.0
CMS1_k127_1004714_11 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002575 250.0
CMS1_k127_1004714_12 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000002716 229.0
CMS1_k127_1004714_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004234 223.0
CMS1_k127_1004714_14 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000000000000000001339 209.0
CMS1_k127_1004714_15 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.0000000000000000000000000000000000000000000000000000001522 203.0
CMS1_k127_1004714_16 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000009879 188.0
CMS1_k127_1004714_17 oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000000000000007595 162.0
CMS1_k127_1004714_18 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000005077 162.0
CMS1_k127_1004714_19 - - - - 0.00000000000000000000000000000000000000006665 153.0
CMS1_k127_1004714_2 diguanylate cyclase - - - 9.325e-250 784.0
CMS1_k127_1004714_20 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000001938 66.0
CMS1_k127_1004714_21 Transcriptional regulatory protein, C terminal - - - 0.000003952 58.0
CMS1_k127_1004714_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 1.403e-218 681.0
CMS1_k127_1004714_4 sulfate adenylyltransferase K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 595.0
CMS1_k127_1004714_5 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 490.0
CMS1_k127_1004714_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 470.0
CMS1_k127_1004714_7 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 389.0
CMS1_k127_1004714_8 phosphorelay sensor kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 358.0
CMS1_k127_1004714_9 4fe-4s ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 301.0
CMS1_k127_1049519_0 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 439.0
CMS1_k127_1049519_1 phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 361.0
CMS1_k127_1049519_2 RNA-binding protein homologous to eukaryotic snRNP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 324.0
CMS1_k127_1049519_3 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000000005642 195.0
CMS1_k127_1049519_4 - - - - 0.00000003611 59.0
CMS1_k127_1061658_0 ABC transporter K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 469.0
CMS1_k127_1061658_1 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 376.0
CMS1_k127_1061658_2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.000000000000000000000000000000000000000001522 177.0
CMS1_k127_1061658_3 self proteolysis - - - 0.00000000000006496 79.0
CMS1_k127_1061658_4 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000002374 81.0
CMS1_k127_1061658_5 Protein of unknown function (DUF1566) K07126 - - 0.000000008925 66.0
CMS1_k127_1066406_0 Atp-dependent helicase K03579 - 3.6.4.13 4.615e-284 895.0
CMS1_k127_1066406_1 PFAM TrkA-N domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 572.0
CMS1_k127_1066406_2 Protein of unknown function (DUF808) K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005592 392.0
CMS1_k127_1066406_3 Flagellar motor protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 324.0
CMS1_k127_1066406_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001423 278.0
CMS1_k127_1066406_5 - - - - 0.00000000000000000000000000000000000000000000000001273 182.0
CMS1_k127_1066406_7 Chemoreceptor zinc-binding domain - - - 0.00000000000000000006381 91.0
CMS1_k127_1089007_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.626e-270 834.0
CMS1_k127_1089007_1 Phospholipid glycerol acyltransferase - - - 2.272e-233 735.0
CMS1_k127_1089007_10 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001557 229.0
CMS1_k127_1089007_11 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000001655 169.0
CMS1_k127_1089007_12 Cytochrome c - - - 0.00000000000000000000000000000000000000000002856 165.0
CMS1_k127_1089007_13 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000002289 156.0
CMS1_k127_1089007_14 - - - - 0.00000000000000000000000000001303 120.0
CMS1_k127_1089007_15 - - - - 0.0000000000000000000003444 97.0
CMS1_k127_1089007_16 - - - - 0.0000000000009776 70.0
CMS1_k127_1089007_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 590.0
CMS1_k127_1089007_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 444.0
CMS1_k127_1089007_4 Belongs to the pseudouridine synthase RluA family K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 419.0
CMS1_k127_1089007_5 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 375.0
CMS1_k127_1089007_6 COG0642 Signal transduction histidine kinase K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 321.0
CMS1_k127_1089007_7 phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 304.0
CMS1_k127_1089007_9 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001668 258.0
CMS1_k127_1091366_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1487.0
CMS1_k127_1091366_1 ABC transporter, ATP-binding protein K15738 - - 4.051e-315 975.0
CMS1_k127_1091366_10 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 7.906e-199 624.0
CMS1_k127_1091366_11 Belongs to the MurCDEF family K01924 - 6.3.2.8 7.442e-195 616.0
CMS1_k127_1091366_12 transporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 604.0
CMS1_k127_1091366_13 COG0436 Aspartate tyrosine aromatic aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 557.0
CMS1_k127_1091366_14 potassium channel protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 564.0
CMS1_k127_1091366_15 Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 538.0
CMS1_k127_1091366_16 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 467.0
CMS1_k127_1091366_17 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 428.0
CMS1_k127_1091366_18 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 409.0
CMS1_k127_1091366_19 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 390.0
CMS1_k127_1091366_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.207e-312 967.0
CMS1_k127_1091366_20 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 378.0
CMS1_k127_1091366_21 hydrolase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 355.0
CMS1_k127_1091366_22 asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 367.0
CMS1_k127_1091366_23 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 331.0
CMS1_k127_1091366_24 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 297.0
CMS1_k127_1091366_25 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004454 282.0
CMS1_k127_1091366_26 Belongs to the protein N5-glutamine methyltransferase family K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002315 270.0
CMS1_k127_1091366_27 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008258 247.0
CMS1_k127_1091366_28 - - - - 0.000000000000000000000000000000000000000000000000000000000000002685 221.0
CMS1_k127_1091366_29 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000003501 221.0
CMS1_k127_1091366_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090 - 4.594e-297 927.0
CMS1_k127_1091366_30 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000005335 209.0
CMS1_k127_1091366_31 - - - - 0.00000000000000000000000000000000000000000000000000000003426 205.0
CMS1_k127_1091366_32 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000151 198.0
CMS1_k127_1091366_33 Hemolysin K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000003145 196.0
CMS1_k127_1091366_34 RDD family - - - 0.0000000000000000000000000000000000000000000000000008472 192.0
CMS1_k127_1091366_35 TrkA-N domain K10716 - - 0.00000000000000000000000000000000000000000002417 169.0
CMS1_k127_1091366_36 Stress responsive A B Barrel Domain - - - 0.0000000000000000000000000000007996 124.0
CMS1_k127_1091366_37 - - - - 0.0000000000000000000000000001221 119.0
CMS1_k127_1091366_38 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000000000000005278 112.0
CMS1_k127_1091366_39 cytochrome - - - 0.0000000000000000000002292 104.0
CMS1_k127_1091366_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 3.046e-251 781.0
CMS1_k127_1091366_40 - - - - 0.00000000000000000000128 99.0
CMS1_k127_1091366_43 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000006977 73.0
CMS1_k127_1091366_46 - - - - 0.000007976 48.0
CMS1_k127_1091366_5 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.296e-250 777.0
CMS1_k127_1091366_6 ABC-type multidrug transport system ATPase and permease - - - 1.221e-244 769.0
CMS1_k127_1091366_7 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.067e-234 730.0
CMS1_k127_1091366_8 o-acetylhomoserine K01740 - 2.5.1.49 6.744e-221 690.0
CMS1_k127_1091366_9 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 3.076e-208 657.0
CMS1_k127_1106562_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1056.0
CMS1_k127_1106562_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 4.716e-312 972.0
CMS1_k127_1106562_10 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 499.0
CMS1_k127_1106562_11 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 481.0
CMS1_k127_1106562_12 Guanosine pentaphosphate phosphohydrolase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 480.0
CMS1_k127_1106562_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009757 475.0
CMS1_k127_1106562_14 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009082 427.0
CMS1_k127_1106562_15 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 411.0
CMS1_k127_1106562_16 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 422.0
CMS1_k127_1106562_17 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 400.0
CMS1_k127_1106562_18 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 391.0
CMS1_k127_1106562_19 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 379.0
CMS1_k127_1106562_2 Fatty acid cis/trans isomerase (CTI) - - - 2.302e-288 905.0
CMS1_k127_1106562_20 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 374.0
CMS1_k127_1106562_21 riboflavin biosynthesis protein K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 379.0
CMS1_k127_1106562_22 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 361.0
CMS1_k127_1106562_23 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 351.0
CMS1_k127_1106562_24 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 325.0
CMS1_k127_1106562_25 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 338.0
CMS1_k127_1106562_26 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 320.0
CMS1_k127_1106562_27 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 309.0
CMS1_k127_1106562_28 Hep Hag repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 346.0
CMS1_k127_1106562_29 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 291.0
CMS1_k127_1106562_3 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 582.0
CMS1_k127_1106562_30 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000001048 265.0
CMS1_k127_1106562_31 ribonuclease BN K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002814 253.0
CMS1_k127_1106562_32 Formylmethanofuran dehydrogenase, subunit e - - - 0.00000000000000000000000000000000000000000000000000000000000000002248 230.0
CMS1_k127_1106562_33 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000001431 192.0
CMS1_k127_1106562_34 COG1214 Inactive homolog of metal-dependent proteases - - - 0.00000000000000000000000000000000000000000000000000001359 193.0
CMS1_k127_1106562_35 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000001178 200.0
CMS1_k127_1106562_36 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000004706 189.0
CMS1_k127_1106562_37 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000146 177.0
CMS1_k127_1106562_38 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000008414 162.0
CMS1_k127_1106562_39 Ferredoxin K05337 - - 0.0000000000000000000000000000000000000000168 153.0
CMS1_k127_1106562_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 572.0
CMS1_k127_1106562_40 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000002903 133.0
CMS1_k127_1106562_41 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000009089 108.0
CMS1_k127_1106562_42 nucleic-acid-binding protein implicated in transcription termination - - - 0.0000000000000855 74.0
CMS1_k127_1106562_43 Hep Hag repeat protein - - - 0.0002612 56.0
CMS1_k127_1106562_5 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 556.0
CMS1_k127_1106562_6 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 522.0
CMS1_k127_1106562_7 peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 525.0
CMS1_k127_1106562_8 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 511.0
CMS1_k127_1106562_9 COG0402 Cytosine deaminase and related metal-dependent K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 509.0
CMS1_k127_115684_0 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 2.395e-254 791.0
CMS1_k127_115684_1 PFAM Bacterial transcription activator, effector binding domain K13652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 450.0
CMS1_k127_115684_3 Transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 352.0
CMS1_k127_115684_4 PFAM Ferredoxin thioredoxin reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 299.0
CMS1_k127_115684_5 - - - - 0.0000000000000000000000000000000000000000000000000000000006734 205.0
CMS1_k127_115684_6 CAAX protease self-immunity - - - 0.00000000000000000000000000000000000000000002178 169.0
CMS1_k127_115684_7 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000000000000005531 112.0
CMS1_k127_115684_8 Domain of unknown function (DUF4430) - - - 0.00000000000000000000000003285 112.0
CMS1_k127_1170321_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.471e-298 931.0
CMS1_k127_1170321_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 8.053e-259 805.0
CMS1_k127_1170321_10 RDD family - - - 0.000000000000000000000000000000000000000002313 160.0
CMS1_k127_1170321_11 - - - - 0.000000000000000000000000000000007901 132.0
CMS1_k127_1170321_12 Histidine kinase - - - 0.000000000000000000000000003081 114.0
CMS1_k127_1170321_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 9.263e-254 795.0
CMS1_k127_1170321_3 Belongs to the GARS family K01945 - 6.3.4.13 1.124e-231 723.0
CMS1_k127_1170321_4 COG1055 Na H antiporter NhaD and related arsenite - - - 3.944e-223 700.0
CMS1_k127_1170321_5 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 4.345e-214 689.0
CMS1_k127_1170321_6 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.28e-213 671.0
CMS1_k127_1170321_7 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001091 245.0
CMS1_k127_1170321_8 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K03776 - - 0.0000000000000000000000000000000000000000000000000000000000000006165 221.0
CMS1_k127_1170321_9 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000004768 177.0
CMS1_k127_1174495_0 hmm pf00534 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 321.0
CMS1_k127_1174495_1 Uncharacterised nucleotidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 314.0
CMS1_k127_1180062_0 HI0933-like protein K07007 - - 9.447e-209 656.0
CMS1_k127_1180062_1 Magnesium transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 434.0
CMS1_k127_1180062_2 Domain of unknown function (DUF4136) - - - 0.0000000000000000001984 94.0
CMS1_k127_1180062_3 helix_turn_helix, mercury resistance - - - 0.0002641 50.0
CMS1_k127_1187327_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1060.0
CMS1_k127_1187327_1 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member K03581 - 3.1.11.5 0.0 1029.0
CMS1_k127_1187327_10 Psort location Cytoplasmic, score 9.97 - - - 0.0000000000000000000000000000000000000006824 158.0
CMS1_k127_1187327_11 Belongs to the Fur family K09825 - - 0.000000000000000000000000000000000000002813 150.0
CMS1_k127_1187327_12 epimerase - - - 0.000000000000000000000000000001753 130.0
CMS1_k127_1187327_13 - - - - 0.0000000000000000000000000000597 121.0
CMS1_k127_1187327_14 Cytochrome c553 K08738 - - 0.000000000000000000000001384 105.0
CMS1_k127_1187327_15 - - - - 0.00000000000000001593 83.0
CMS1_k127_1187327_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.263e-290 899.0
CMS1_k127_1187327_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 547.0
CMS1_k127_1187327_4 Cytochrome K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 490.0
CMS1_k127_1187327_5 Na H antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 449.0
CMS1_k127_1187327_6 Histidine kinase K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 384.0
CMS1_k127_1187327_7 membrane-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007234 271.0
CMS1_k127_1187327_8 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000948 270.0
CMS1_k127_1187327_9 COGs COG3786 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000978 226.0
CMS1_k127_1203891_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1241.0
CMS1_k127_1203891_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 3.732e-311 954.0
CMS1_k127_1203891_10 FGGY family of carbohydrate kinases, N-terminal domain K11216 - 2.7.1.189 2.335e-216 682.0
CMS1_k127_1203891_11 Belongs to the CarA family K01956 - 6.3.5.5 4.903e-201 631.0
CMS1_k127_1203891_12 transporter - - - 7.243e-198 625.0
CMS1_k127_1203891_13 malic enzyme K00027,K00029 - 1.1.1.38,1.1.1.40 2.19e-197 622.0
CMS1_k127_1203891_14 pyruvate ferredoxin oxidoreductase K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 601.0
CMS1_k127_1203891_15 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 588.0
CMS1_k127_1203891_16 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 557.0
CMS1_k127_1203891_17 molybdopterin biosynthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 520.0
CMS1_k127_1203891_18 PFAM Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 486.0
CMS1_k127_1203891_19 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 417.0
CMS1_k127_1203891_2 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 1.155e-269 857.0
CMS1_k127_1203891_20 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 392.0
CMS1_k127_1203891_21 PFAM tRNA synthetase class II (G H P and S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 388.0
CMS1_k127_1203891_22 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 373.0
CMS1_k127_1203891_23 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 361.0
CMS1_k127_1203891_24 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 359.0
CMS1_k127_1203891_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 361.0
CMS1_k127_1203891_26 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 346.0
CMS1_k127_1203891_27 S1 domain K00243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 345.0
CMS1_k127_1203891_28 modulator of drug activity K03923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 335.0
CMS1_k127_1203891_29 pyruvate ferredoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 329.0
CMS1_k127_1203891_3 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 4.423e-266 833.0
CMS1_k127_1203891_30 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 317.0
CMS1_k127_1203891_31 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 303.0
CMS1_k127_1203891_32 riboflavin synthase alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 298.0
CMS1_k127_1203891_33 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 291.0
CMS1_k127_1203891_34 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) K07173 - 4.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 286.0
CMS1_k127_1203891_35 Hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 287.0
CMS1_k127_1203891_36 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002809 282.0
CMS1_k127_1203891_37 protein conserved in bacteria K09804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001559 271.0
CMS1_k127_1203891_38 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000821 269.0
CMS1_k127_1203891_39 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000006887 252.0
CMS1_k127_1203891_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.444e-242 754.0
CMS1_k127_1203891_40 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007906 244.0
CMS1_k127_1203891_41 pyruvate ferredoxin oxidoreductase K00171 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000005325 241.0
CMS1_k127_1203891_42 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002583 239.0
CMS1_k127_1203891_43 molybdopterin converting factor K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000001452 235.0
CMS1_k127_1203891_44 Peptidyl-prolyl cis-trans isomerase K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000003378 239.0
CMS1_k127_1203891_45 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000001783 230.0
CMS1_k127_1203891_46 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000000000000000000000000000000000000004363 237.0
CMS1_k127_1203891_47 PFAM Methyltransferase type - - - 0.00000000000000000000000000000000000000000000000000000000000000009751 228.0
CMS1_k127_1203891_48 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000000000002016 218.0
CMS1_k127_1203891_49 - - - - 0.000000000000000000000000000000000000000000000000000000000001449 226.0
CMS1_k127_1203891_5 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 5.529e-238 741.0
CMS1_k127_1203891_50 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000001896 220.0
CMS1_k127_1203891_51 carbonic anhydrase K01674 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000819 213.0
CMS1_k127_1203891_52 PFAM methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000001043 210.0
CMS1_k127_1203891_53 ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000197 198.0
CMS1_k127_1203891_54 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000787 200.0
CMS1_k127_1203891_55 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000001088 190.0
CMS1_k127_1203891_56 FixH - - - 0.00000000000000000000000000000000000000000000000002303 185.0
CMS1_k127_1203891_57 - - - - 0.00000000000000000000000000000000000000000000242 169.0
CMS1_k127_1203891_58 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000005916 166.0
CMS1_k127_1203891_59 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000009621 156.0
CMS1_k127_1203891_6 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 5.996e-224 698.0
CMS1_k127_1203891_60 COG1393 Arsenate reductase and related K00537 - 1.20.4.1 0.0000000000000000000000000000000000000006992 156.0
CMS1_k127_1203891_61 - - - - 0.00000000000000000000000000000000000003636 148.0
CMS1_k127_1203891_62 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000000000000000000037 134.0
CMS1_k127_1203891_63 - - - - 0.00000000000000000000000000000007551 128.0
CMS1_k127_1203891_64 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000009527 123.0
CMS1_k127_1203891_65 molybdopterin converting factor K03636 - - 0.000000000000000000000000000001518 121.0
CMS1_k127_1203891_66 OmpA-like transmembrane domain - - - 0.00000000000000000000000000002413 124.0
CMS1_k127_1203891_67 oxygen carrier activity K07216 - - 0.0000000000000000000000000001197 119.0
CMS1_k127_1203891_68 Domain of unknown function (DUF3817) - - - 0.00000000000000000000005105 104.0
CMS1_k127_1203891_69 Family of unknown function (DUF4006) - - - 0.00000000000000000001185 93.0
CMS1_k127_1203891_7 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.466e-221 692.0
CMS1_k127_1203891_70 Rubredoxin - - - 0.00000000000000000001387 91.0
CMS1_k127_1203891_71 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.00000000000000000001603 94.0
CMS1_k127_1203891_72 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000003324 72.0
CMS1_k127_1203891_74 Outer membrane porin - - - 0.0000000000168 76.0
CMS1_k127_1203891_76 Sulfatase-modifying factor enzyme 1 K11912 - 2.7.11.1 0.00001163 54.0
CMS1_k127_1203891_8 COG3893 inactivated superfamily I helicase - - - 2.706e-217 700.0
CMS1_k127_1203891_9 Abc transporter K02035 - - 7.795e-217 683.0
CMS1_k127_1216974_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.009e-315 970.0
CMS1_k127_1216974_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 3.013e-312 971.0
CMS1_k127_1216974_10 Belongs to the BI1 family K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 343.0
CMS1_k127_1216974_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 338.0
CMS1_k127_1216974_12 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 335.0
CMS1_k127_1216974_13 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 323.0
CMS1_k127_1216974_14 Methyltransferase domain K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005402 286.0
CMS1_k127_1216974_15 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009267 270.0
CMS1_k127_1216974_16 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001643 252.0
CMS1_k127_1216974_17 Uncharacterized protein domain (DUF2202) - - - 0.0000000000000000000000000000000000000000000000000000000000001692 219.0
CMS1_k127_1216974_18 thiamine-phosphate diphosphorylase activity K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000001502 188.0
CMS1_k127_1216974_19 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000001067 177.0
CMS1_k127_1216974_2 Single-stranded-DNA-specific exonuclease (RecJ) K07462 - - 1.969e-201 640.0
CMS1_k127_1216974_20 Preprotein translocase subunit SecG K03075 - - 0.0000000000000000000000000000000000000003646 151.0
CMS1_k127_1216974_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 599.0
CMS1_k127_1216974_4 Belongs to the UPF0324 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 512.0
CMS1_k127_1216974_5 COG0348 Polyferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 451.0
CMS1_k127_1216974_6 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 410.0
CMS1_k127_1216974_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 364.0
CMS1_k127_1216974_8 ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 360.0
CMS1_k127_1216974_9 Abc transporter K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009211 346.0
CMS1_k127_136324_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 2.088e-254 790.0
CMS1_k127_136324_1 Glycerol-3-phosphate dehydrogenase K11473 - - 2.029e-242 753.0
CMS1_k127_136324_10 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 363.0
CMS1_k127_136324_11 MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 354.0
CMS1_k127_136324_12 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 332.0
CMS1_k127_136324_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002559 278.0
CMS1_k127_136324_14 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000000000003103 227.0
CMS1_k127_136324_15 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000000000006919 200.0
CMS1_k127_136324_16 Protein of unknown function (DUF3450) - - - 0.00000000000000000000000000000000000000000000000000000001233 207.0
CMS1_k127_136324_17 PFAM DsrE DsrF-like family - - - 0.000000000000000000000000000000000000000000000006569 173.0
CMS1_k127_136324_18 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000352 173.0
CMS1_k127_136324_19 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000003618 166.0
CMS1_k127_136324_2 MgtC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 586.0
CMS1_k127_136324_20 - - - - 0.000000000000000000006529 95.0
CMS1_k127_136324_21 - - - - 0.0000000000001473 77.0
CMS1_k127_136324_22 glutathione-regulated potassium exporter activity K01537 - 3.6.3.8 0.00001376 51.0
CMS1_k127_136324_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 543.0
CMS1_k127_136324_4 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 480.0
CMS1_k127_136324_5 Belongs to the mannose-6-phosphate isomerase type 2 family K00971 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 441.0
CMS1_k127_136324_6 acid membrane antigen A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 398.0
CMS1_k127_136324_7 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 390.0
CMS1_k127_136324_8 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 388.0
CMS1_k127_136324_9 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 381.0
CMS1_k127_1489511_0 Belongs to the UPF0246 family K09861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 316.0
CMS1_k127_1489511_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004023 271.0
CMS1_k127_1489511_2 COGs COG2829 Outer membrane phospholipase A K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000000000000000000000000003882 226.0
CMS1_k127_1489511_3 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000002771 183.0
CMS1_k127_1489511_4 Thioredoxin - - - 0.0000000000002871 70.0
CMS1_k127_1489511_5 PFAM Ion transport 2 domain protein - - - 0.000001824 53.0
CMS1_k127_1502404_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1926.0
CMS1_k127_1502404_1 Belongs to the DNA mismatch repair MutS family K03555 - - 0.0 1511.0
CMS1_k127_1502404_2 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 557.0
CMS1_k127_1502404_3 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 320.0
CMS1_k127_1542373_0 Highly conserved protein containing a thioredoxin domain K06888 - - 7.135e-253 795.0
CMS1_k127_1542373_1 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09014 - - 6.32e-252 783.0
CMS1_k127_1542373_10 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 524.0
CMS1_k127_1542373_11 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 482.0
CMS1_k127_1542373_12 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 471.0
CMS1_k127_1542373_13 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 466.0
CMS1_k127_1542373_14 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 443.0
CMS1_k127_1542373_15 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 439.0
CMS1_k127_1542373_16 polyphosphate kinase K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 414.0
CMS1_k127_1542373_17 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 407.0
CMS1_k127_1542373_18 COG0396 ABC-type transport system involved in Fe-S cluster assembly ATPase component K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 373.0
CMS1_k127_1542373_19 hmm pf04305 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 366.0
CMS1_k127_1542373_2 threonine synthase K01733 - 4.2.3.1 1.18e-246 769.0
CMS1_k127_1542373_20 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 366.0
CMS1_k127_1542373_21 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 357.0
CMS1_k127_1542373_22 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 319.0
CMS1_k127_1542373_23 COG0719 ABC-type transport system involved in Fe-S cluster assembly permease component K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005336 313.0
CMS1_k127_1542373_24 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 300.0
CMS1_k127_1542373_25 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000002072 244.0
CMS1_k127_1542373_26 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002433 241.0
CMS1_k127_1542373_27 PFAM O-methyltransferase, family 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001262 236.0
CMS1_k127_1542373_29 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000001509 220.0
CMS1_k127_1542373_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.709e-229 715.0
CMS1_k127_1542373_30 Chemoreceptor zinc-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000002318 214.0
CMS1_k127_1542373_31 Bacterial transcriptional repressor - - - 0.00000000000000000000000000000000000000000000000000000000000727 213.0
CMS1_k127_1542373_32 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000001022 203.0
CMS1_k127_1542373_33 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000001125 205.0
CMS1_k127_1542373_34 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000001858 201.0
CMS1_k127_1542373_35 Cytochrome c family protein - - - 0.0000000000000000000000000000000000000000000000000000002284 199.0
CMS1_k127_1542373_36 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000006283 189.0
CMS1_k127_1542373_37 COG2199 FOG GGDEF domain - - - 0.000000000000000000000000000000000000000000006901 174.0
CMS1_k127_1542373_38 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000002951 166.0
CMS1_k127_1542373_39 - - - - 0.0000000000000000000000000000000000000000009653 160.0
CMS1_k127_1542373_4 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 3.469e-227 719.0
CMS1_k127_1542373_40 COG2166 SufE protein probably involved in Fe-S center assembly K02426 - - 0.0000000000000000000000000000000000000003229 153.0
CMS1_k127_1542373_41 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000011 150.0
CMS1_k127_1542373_42 thioesterase K02614 - - 0.00000000000000000000000000000000000005538 147.0
CMS1_k127_1542373_43 cytochrome c class I - - - 0.00000000000000000000000000000000001644 141.0
CMS1_k127_1542373_44 Chorismate mutase K04782 - 4.2.99.21 0.0000000000000000000000000000000000187 137.0
CMS1_k127_1542373_45 Inositol monophosphatase - - - 0.0000000000000000000000000000000004786 135.0
CMS1_k127_1542373_46 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000000005242 126.0
CMS1_k127_1542373_47 Outer membrane efflux protein - - - 0.000000000000000000000000000001558 130.0
CMS1_k127_1542373_48 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000001498 121.0
CMS1_k127_1542373_49 2'-5' RNA ligase K01975 - 3.1.4.58 0.0000000000000000000000000009515 118.0
CMS1_k127_1542373_5 Endoribonuclease that initiates mRNA decay K18682 - - 5.067e-222 699.0
CMS1_k127_1542373_50 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000001255 112.0
CMS1_k127_1542373_51 Rhodanese Homology Domain - - - 0.0000000000000000000000002291 113.0
CMS1_k127_1542373_52 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000003352 106.0
CMS1_k127_1542373_53 thiamine biosynthesis protein ThiS K03154 - - 0.0000000000000000003818 89.0
CMS1_k127_1542373_54 Protein conserved in bacteria K09764 - - 0.000000000000000009357 86.0
CMS1_k127_1542373_56 - - - - 0.00000000000000004548 84.0
CMS1_k127_1542373_57 - - - - 0.00000004537 62.0
CMS1_k127_1542373_6 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 6.386e-195 621.0
CMS1_k127_1542373_7 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 597.0
CMS1_k127_1542373_8 ABC transporter K06148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 581.0
CMS1_k127_1542373_9 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 536.0
CMS1_k127_163793_0 Sulfate permease family - - - 1.974e-228 717.0
CMS1_k127_163793_1 alanine symporter K03310 - - 1.435e-194 616.0
CMS1_k127_163793_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 499.0
CMS1_k127_163793_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 314.0
CMS1_k127_163793_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003387 261.0
CMS1_k127_1661944_0 Cytochrome c554 and c-prime - - - 2.857e-274 861.0
CMS1_k127_1661944_1 Cache domain - - - 1.602e-264 820.0
CMS1_k127_1661944_2 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 347.0
CMS1_k127_1661944_3 Dtw domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 325.0
CMS1_k127_1661944_6 Bacterial transcription activator, effector binding domain - - - 0.00000000000000000000000000007706 121.0
CMS1_k127_1673304_0 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 452.0
CMS1_k127_1673304_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 381.0
CMS1_k127_1673304_10 PKD domain - - - 0.0000000000000000008764 95.0
CMS1_k127_1673304_2 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 328.0
CMS1_k127_1673304_3 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 333.0
CMS1_k127_1673304_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 290.0
CMS1_k127_1673304_5 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.000000000000000000000000000000000000000000000000005542 187.0
CMS1_k127_1673304_6 Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000000000000000000000000001592 184.0
CMS1_k127_1673304_7 Thrombospondin type 3 repeat K03286 - - 0.00000000000000000000000000000000000003642 152.0
CMS1_k127_1673304_8 - - - - 0.0000000000000000000000000000000001003 139.0
CMS1_k127_1673304_9 PFAM PKD domain containing protein - - - 0.00000000000000000000003448 113.0
CMS1_k127_1805763_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 555.0
CMS1_k127_1805763_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 317.0
CMS1_k127_1805763_2 Pseudouridine synthase K06177,K06179,K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 309.0
CMS1_k127_1829433_0 glutathione-regulated potassium exporter activity K01537 - 3.6.3.8 6.792e-197 619.0
CMS1_k127_1829433_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 283.0
CMS1_k127_1829433_2 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.00000000000234 69.0
CMS1_k127_1846860_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 6.719e-211 660.0
CMS1_k127_1846860_1 Cytochrome c - - - 1.119e-201 645.0
CMS1_k127_1846860_10 - - - - 0.000000000001459 74.0
CMS1_k127_1846860_11 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 0.00000007853 60.0
CMS1_k127_1846860_2 Bacterial protein of unknown function (DUF839) K07093 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 592.0
CMS1_k127_1846860_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 553.0
CMS1_k127_1846860_4 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 454.0
CMS1_k127_1846860_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 308.0
CMS1_k127_1846860_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001933 280.0
CMS1_k127_1846860_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001374 251.0
CMS1_k127_1846860_8 DoxX family K15977 - - 0.000000000000000000000000000000000000000000000000001241 186.0
CMS1_k127_1846860_9 - - - - 0.00000000000000000000000000000006349 127.0
CMS1_k127_1868994_0 Efflux pump membrane transporter K03296,K18138 - - 0.0 1499.0
CMS1_k127_1868994_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1485.0
CMS1_k127_1868994_10 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 3.259e-215 674.0
CMS1_k127_1868994_11 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 585.0
CMS1_k127_1868994_12 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 589.0
CMS1_k127_1868994_13 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 567.0
CMS1_k127_1868994_14 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 555.0
CMS1_k127_1868994_15 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 477.0
CMS1_k127_1868994_16 general secretion pathway protein D K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 428.0
CMS1_k127_1868994_17 COG1459 Type II secretory pathway, component PulF K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 412.0
CMS1_k127_1868994_18 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 379.0
CMS1_k127_1868994_19 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 374.0
CMS1_k127_1868994_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0 1125.0
CMS1_k127_1868994_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 377.0
CMS1_k127_1868994_21 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 376.0
CMS1_k127_1868994_22 RND efflux system, outer membrane lipoprotein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 371.0
CMS1_k127_1868994_23 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 334.0
CMS1_k127_1868994_24 NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 308.0
CMS1_k127_1868994_25 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006518 295.0
CMS1_k127_1868994_26 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 284.0
CMS1_k127_1868994_27 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 283.0
CMS1_k127_1868994_28 PFAM Resolvase, N terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000129 254.0
CMS1_k127_1868994_29 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002157 251.0
CMS1_k127_1868994_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1090.0
CMS1_k127_1868994_30 FIST N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004369 248.0
CMS1_k127_1868994_31 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000864 214.0
CMS1_k127_1868994_32 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000000003242 192.0
CMS1_k127_1868994_33 Belongs to the globin family K05916 - 1.14.12.17 0.000000000000000000000000000000000000000000000000000004632 193.0
CMS1_k127_1868994_34 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000216 181.0
CMS1_k127_1868994_35 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000249 181.0
CMS1_k127_1868994_36 Transcriptional regulator K03892 - - 0.0000000000000000000000000000000000000000000006109 168.0
CMS1_k127_1868994_37 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000003009 139.0
CMS1_k127_1868994_38 - - - - 0.00000000000000000000000000000002963 136.0
CMS1_k127_1868994_39 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000001204 106.0
CMS1_k127_1868994_4 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K03455,K11747 - - 3.479e-250 782.0
CMS1_k127_1868994_40 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000001299 112.0
CMS1_k127_1868994_41 radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 1.15.1.1 0.00000000000000000000008835 100.0
CMS1_k127_1868994_42 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000004255 102.0
CMS1_k127_1868994_43 - - - - 0.0000000000000003092 89.0
CMS1_k127_1868994_44 - - - - 0.000000000000000749 84.0
CMS1_k127_1868994_45 proline dehydrogenase activity - - - 0.000000000005452 77.0
CMS1_k127_1868994_46 Prokaryotic N-terminal methylation motif - - - 0.000000006148 63.0
CMS1_k127_1868994_47 - - - - 0.00000001825 62.0
CMS1_k127_1868994_48 - - - - 0.0000001088 56.0
CMS1_k127_1868994_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 8.123e-247 773.0
CMS1_k127_1868994_6 Cytochrome c oxidase accessory protein - - - 3.779e-230 728.0
CMS1_k127_1868994_7 pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 5.984e-230 721.0
CMS1_k127_1868994_8 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.096e-224 701.0
CMS1_k127_1868994_9 HD domain - - - 5.075e-223 715.0
CMS1_k127_1869987_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.157e-321 992.0
CMS1_k127_1869987_1 His Kinase A (phosphoacceptor) domain - - - 1.57e-239 758.0
CMS1_k127_1869987_10 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 375.0
CMS1_k127_1869987_11 General glycosylation pathway protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 376.0
CMS1_k127_1869987_12 Two-component sensor histidine kinase response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 386.0
CMS1_k127_1869987_13 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 355.0
CMS1_k127_1869987_14 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 359.0
CMS1_k127_1869987_15 signal transduction response regulator (GGDEF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 360.0
CMS1_k127_1869987_16 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 338.0
CMS1_k127_1869987_17 FIST C domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 341.0
CMS1_k127_1869987_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 323.0
CMS1_k127_1869987_19 Belongs to the mannose-6-phosphate isomerase type 2 family K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 316.0
CMS1_k127_1869987_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.388e-201 634.0
CMS1_k127_1869987_20 GHKL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 320.0
CMS1_k127_1869987_21 PAS domain K03776 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001243 274.0
CMS1_k127_1869987_22 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001649 250.0
CMS1_k127_1869987_23 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000103 247.0
CMS1_k127_1869987_24 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001027 237.0
CMS1_k127_1869987_25 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000000115 228.0
CMS1_k127_1869987_27 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000001484 183.0
CMS1_k127_1869987_28 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000007095 199.0
CMS1_k127_1869987_29 glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000005939 171.0
CMS1_k127_1869987_3 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008444 632.0
CMS1_k127_1869987_30 signal transduction sensor histidine kinase - - - 0.000000000000000000000000000000000000000001264 161.0
CMS1_k127_1869987_31 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000007167 154.0
CMS1_k127_1869987_32 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0000000000000000000000000000000000004905 147.0
CMS1_k127_1869987_33 - - - - 0.0000000000000000000000000000000000005303 142.0
CMS1_k127_1869987_34 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000005813 140.0
CMS1_k127_1869987_35 - - - - 0.0000000000000000000000000000000008932 132.0
CMS1_k127_1869987_36 ankyrin 3, node of Ranvier (ankyrin G) - - - 0.00000000000000000000000000000005958 141.0
CMS1_k127_1869987_37 - - - - 0.00000000000000003927 85.0
CMS1_k127_1869987_38 Sel1-like repeats. K07126 - - 0.00000000000005156 85.0
CMS1_k127_1869987_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 605.0
CMS1_k127_1869987_40 Hpt sensor hybrid histidine kinase - - - 0.0000003906 55.0
CMS1_k127_1869987_5 Nucleotidyltransferase DNA polymerase involved in DNA repair K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 574.0
CMS1_k127_1869987_6 Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 427.0
CMS1_k127_1869987_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 401.0
CMS1_k127_1869987_8 lipopolysaccharide heptosyltransferase K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 383.0
CMS1_k127_1869987_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 413.0
CMS1_k127_1905735_0 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1139.0
CMS1_k127_1905735_1 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0 1132.0
CMS1_k127_1905735_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 5.692e-197 625.0
CMS1_k127_1905735_3 PFAM Galactose-1-phosphate uridyl transferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000002792 209.0
CMS1_k127_1905735_4 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000001052 196.0
CMS1_k127_1905735_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000415 64.0
CMS1_k127_1908333_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1212.0
CMS1_k127_1908333_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1016.0
CMS1_k127_1908333_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 533.0
CMS1_k127_1908333_11 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 516.0
CMS1_k127_1908333_12 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 508.0
CMS1_k127_1908333_13 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 507.0
CMS1_k127_1908333_14 molybdopterin biosynthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 505.0
CMS1_k127_1908333_15 ubiquinol cytochrome c oxidoreductase, cytochrome c1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 454.0
CMS1_k127_1908333_16 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 439.0
CMS1_k127_1908333_17 ATPase (AAA K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 416.0
CMS1_k127_1908333_18 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 402.0
CMS1_k127_1908333_19 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 400.0
CMS1_k127_1908333_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.655e-252 782.0
CMS1_k127_1908333_20 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 393.0
CMS1_k127_1908333_21 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 390.0
CMS1_k127_1908333_22 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 364.0
CMS1_k127_1908333_23 Receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 372.0
CMS1_k127_1908333_24 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 359.0
CMS1_k127_1908333_25 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008591 368.0
CMS1_k127_1908333_26 Receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 341.0
CMS1_k127_1908333_27 ribosomal protein L3 K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 318.0
CMS1_k127_1908333_28 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 316.0
CMS1_k127_1908333_29 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 317.0
CMS1_k127_1908333_3 Belongs to the aldehyde dehydrogenase family - - - 1.724e-243 758.0
CMS1_k127_1908333_30 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 311.0
CMS1_k127_1908333_31 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 301.0
CMS1_k127_1908333_32 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001369 280.0
CMS1_k127_1908333_33 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001386 272.0
CMS1_k127_1908333_34 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002204 266.0
CMS1_k127_1908333_35 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004811 273.0
CMS1_k127_1908333_36 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008154 270.0
CMS1_k127_1908333_37 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002875 259.0
CMS1_k127_1908333_38 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001154 254.0
CMS1_k127_1908333_39 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000008776 231.0
CMS1_k127_1908333_4 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 8.206e-233 724.0
CMS1_k127_1908333_40 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001149 235.0
CMS1_k127_1908333_41 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000000001627 228.0
CMS1_k127_1908333_42 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000000000004017 209.0
CMS1_k127_1908333_43 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000132 195.0
CMS1_k127_1908333_44 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000000000007451 194.0
CMS1_k127_1908333_45 COG2346 Truncated hemoglobins K06886 - - 0.00000000000000000000000000000000000000000000000000001195 192.0
CMS1_k127_1908333_46 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000001317 195.0
CMS1_k127_1908333_47 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000005914 188.0
CMS1_k127_1908333_48 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000001354 184.0
CMS1_k127_1908333_49 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000000000000000001419 177.0
CMS1_k127_1908333_5 Aminotransferase K14261 - - 1.384e-231 720.0
CMS1_k127_1908333_50 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000001896 176.0
CMS1_k127_1908333_51 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000001513 173.0
CMS1_k127_1908333_52 Protein of unknown function (DUF523) - - - 0.000000000000000000000000000000000000000003035 163.0
CMS1_k127_1908333_53 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000001632 149.0
CMS1_k127_1908333_54 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000000001878 140.0
CMS1_k127_1908333_55 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000006406 138.0
CMS1_k127_1908333_56 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000242 132.0
CMS1_k127_1908333_57 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000001068 124.0
CMS1_k127_1908333_58 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000001244 121.0
CMS1_k127_1908333_59 Protein conserved in bacteria - - - 0.0000000000000000004729 98.0
CMS1_k127_1908333_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 2.284e-227 707.0
CMS1_k127_1908333_60 - - - - 0.00000003897 62.0
CMS1_k127_1908333_7 homoserine dehydrogenase K00003 - 1.1.1.3 9.309e-208 653.0
CMS1_k127_1908333_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 602.0
CMS1_k127_1908333_9 Radical SAM protein K07139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 543.0
CMS1_k127_1962676_0 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 4.391e-251 785.0
CMS1_k127_1962676_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 9.101e-217 681.0
CMS1_k127_1962676_10 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000001354 124.0
CMS1_k127_1962676_11 belongs to the thioredoxin family K03671 - - 0.000000000000000000000005083 105.0
CMS1_k127_1962676_2 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 6.304e-209 654.0
CMS1_k127_1962676_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 449.0
CMS1_k127_1962676_4 PFAM Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 408.0
CMS1_k127_1962676_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000005888 267.0
CMS1_k127_1962676_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005665 263.0
CMS1_k127_1962676_7 fumarate reductase, iron-sulfur protein K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000005153 218.0
CMS1_k127_1962676_8 Cytochrome c - - - 0.00000000000000000000000000000000000000001741 158.0
CMS1_k127_1962676_9 metal cluster binding - - - 0.000000000000000000000000000000003868 133.0
CMS1_k127_2000841_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1420.0
CMS1_k127_2000841_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001016 246.0
CMS1_k127_2000841_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000002503 146.0
CMS1_k127_2043657_0 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 424.0
CMS1_k127_2043657_1 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 345.0
CMS1_k127_2043657_10 helicase activity - - - 0.0000000000000000000000000000000000000000000887 173.0
CMS1_k127_2043657_12 - - - - 0.0000000000000000000000000000000007939 132.0
CMS1_k127_2043657_13 - - - - 0.0000000000000000000000000005588 116.0
CMS1_k127_2043657_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 326.0
CMS1_k127_2043657_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 326.0
CMS1_k127_2043657_4 PFAM bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 315.0
CMS1_k127_2043657_5 SMART zinc finger, CDGSH-type domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000938 281.0
CMS1_k127_2043657_6 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000009667 231.0
CMS1_k127_2043657_7 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001956 228.0
CMS1_k127_2043657_8 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000004155 223.0
CMS1_k127_2043657_9 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000003528 198.0
CMS1_k127_2080646_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 4.17e-295 918.0
CMS1_k127_2080646_1 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 400.0
CMS1_k127_2080646_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004077 277.0
CMS1_k127_2080646_3 Domain of unknown function (DUF4156) - - - 0.000000000000000562 82.0
CMS1_k127_2080646_4 CHAD - - - 0.00000002043 58.0
CMS1_k127_2183027_0 glutamine synthetase K01915 - 6.3.1.2 2.967e-293 903.0
CMS1_k127_2183027_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.3e-287 890.0
CMS1_k127_2183027_11 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.000000000000008515 75.0
CMS1_k127_2183027_12 Immune inhibitor A peptidase M6 - - - 0.00004346 49.0
CMS1_k127_2183027_2 peptidase U32 family K08303 - - 5.345e-230 717.0
CMS1_k127_2183027_3 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 377.0
CMS1_k127_2183027_4 histidinol phosphate phosphatase K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 370.0
CMS1_k127_2183027_5 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 355.0
CMS1_k127_2183027_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 283.0
CMS1_k127_2183027_7 GHKL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007446 256.0
CMS1_k127_2183027_8 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000002179 209.0
CMS1_k127_2183027_9 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000002469 136.0
CMS1_k127_2217533_0 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member K03581 - 3.1.11.5 0.0 1022.0
CMS1_k127_2228424_0 ABC transporter K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 542.0
CMS1_k127_2228424_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 486.0
CMS1_k127_2228424_2 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 338.0
CMS1_k127_2353433_0 Epimerase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 470.0
CMS1_k127_2353433_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 432.0
CMS1_k127_2353433_10 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000006811 161.0
CMS1_k127_2353433_11 LrgA family K06518 - - 0.0000000000000000005717 91.0
CMS1_k127_2353433_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 386.0
CMS1_k127_2353433_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 335.0
CMS1_k127_2353433_4 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 294.0
CMS1_k127_2353433_5 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003217 277.0
CMS1_k127_2353433_6 Ndr family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008362 275.0
CMS1_k127_2353433_7 Exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000361 261.0
CMS1_k127_2353433_8 PFAM LrgB family protein - - - 0.0000000000000000000000000000000000000000000000000002183 197.0
CMS1_k127_2431988_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 4058.0
CMS1_k127_2431988_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 0.0 1044.0
CMS1_k127_2431988_10 DUF1704 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 579.0
CMS1_k127_2431988_11 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 531.0
CMS1_k127_2431988_12 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005367 506.0
CMS1_k127_2431988_13 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007627 466.0
CMS1_k127_2431988_14 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 466.0
CMS1_k127_2431988_15 Membrane protease subunits - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 425.0
CMS1_k127_2431988_16 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 425.0
CMS1_k127_2431988_17 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 421.0
CMS1_k127_2431988_18 PFAM Periplasmic binding protein LacI transcriptional regulator K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 399.0
CMS1_k127_2431988_19 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 404.0
CMS1_k127_2431988_2 abc transporter atp-binding protein - - - 1.157e-295 913.0
CMS1_k127_2431988_20 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 395.0
CMS1_k127_2431988_21 dna polymerase iii K10857 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 364.0
CMS1_k127_2431988_22 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 385.0
CMS1_k127_2431988_23 Amino Acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 365.0
CMS1_k127_2431988_24 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 340.0
CMS1_k127_2431988_25 abc transporter atp-binding protein K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 330.0
CMS1_k127_2431988_26 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 319.0
CMS1_k127_2431988_27 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 309.0
CMS1_k127_2431988_28 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 299.0
CMS1_k127_2431988_29 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 294.0
CMS1_k127_2431988_3 AAA domain - - - 1.1e-239 765.0
CMS1_k127_2431988_30 protein conserved in bacteria K09859 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002506 289.0
CMS1_k127_2431988_31 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b) K07337 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001044 273.0
CMS1_k127_2431988_32 PAS domain K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001339 263.0
CMS1_k127_2431988_33 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001486 260.0
CMS1_k127_2431988_34 Protein of unknown function (DUF2459) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003997 253.0
CMS1_k127_2431988_35 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003427 252.0
CMS1_k127_2431988_36 protein conserved in bacteria K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000009972 238.0
CMS1_k127_2431988_37 SMART GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001569 240.0
CMS1_k127_2431988_38 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000000000000000000000001075 213.0
CMS1_k127_2431988_39 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000000000000000000007236 200.0
CMS1_k127_2431988_4 Spermine/spermidine synthase domain K00797 - 2.5.1.16 3.646e-239 766.0
CMS1_k127_2431988_40 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000001495 196.0
CMS1_k127_2431988_41 - K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000001821 196.0
CMS1_k127_2431988_43 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000003935 167.0
CMS1_k127_2431988_44 Domain of unknown function (DUF4136) - - - 0.00000000000000000000000000000000000000000001415 168.0
CMS1_k127_2431988_45 - - - - 0.0000000000000000000000000000000000000000000164 167.0
CMS1_k127_2431988_46 SEC-C motif K09858 - - 0.0000000000000000000000000000000000000000001313 163.0
CMS1_k127_2431988_47 YjbR - - - 0.000000000000000000000000000000000000000005834 156.0
CMS1_k127_2431988_48 Universal stress protein family - - - 0.000000000000000000000000000000000000000006883 165.0
CMS1_k127_2431988_49 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000008963 156.0
CMS1_k127_2431988_5 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 9.311e-221 705.0
CMS1_k127_2431988_50 - - - - 0.00000000000000000000000000000000000002038 148.0
CMS1_k127_2431988_52 Rhodanese-like domain - - - 0.0000000000000000000000000000000001359 138.0
CMS1_k127_2431988_55 Translation initiation factor SUI1 K03113 - - 0.0000000000000000000000000000228 123.0
CMS1_k127_2431988_56 - - - - 0.0000000000000000000000000001168 120.0
CMS1_k127_2431988_57 RND family efflux transporter, MFP subunit - - - 0.0000000000000000000000002268 119.0
CMS1_k127_2431988_58 S4 domain K14761 - - 0.0000000000000000000000003394 107.0
CMS1_k127_2431988_59 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000000000000008829 110.0
CMS1_k127_2431988_6 Belongs to the RtcB family K14415 - 6.5.1.3 4.813e-217 688.0
CMS1_k127_2431988_60 Protein of unknown function (DUF1653) - - - 0.0000000000000000000001466 98.0
CMS1_k127_2431988_61 Lipoprotein - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.0000000000000002747 84.0
CMS1_k127_2431988_62 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000004192 84.0
CMS1_k127_2431988_63 Protein of unknown function (DUF2892) - - - 0.00000000001761 66.0
CMS1_k127_2431988_66 - - - - 0.000000003145 63.0
CMS1_k127_2431988_67 efflux transmembrane transporter activity - - - 0.0002902 53.0
CMS1_k127_2431988_7 DNA polymerase X family K02347 - - 8.606e-203 646.0
CMS1_k127_2431988_8 growth of symbiont in host cell K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 601.0
CMS1_k127_2431988_9 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 573.0
CMS1_k127_2470365_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1037.0
CMS1_k127_2470365_1 ATP-dependent DNA helicase K03655 - 3.6.4.12 1.777e-225 717.0
CMS1_k127_2470365_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 335.0
CMS1_k127_2470365_3 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.0000000000000000000000000000000000000000000000000000000001092 209.0
CMS1_k127_2470365_4 Response regulator receiver K07814 - - 0.0000000000000000000000000000000000000000000000000002497 186.0
CMS1_k127_2470365_5 - - - - 0.0000000000000000000002858 104.0
CMS1_k127_2470365_6 Prepilin-type N-terminal cleavage methylation domain - - - 0.0000000000002911 72.0
CMS1_k127_257778_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 8.4e-323 1001.0
CMS1_k127_257778_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 2.167e-210 659.0
CMS1_k127_257778_2 2-nitropropane dioxygenase K00459 - 1.13.12.16 6.915e-201 629.0
CMS1_k127_257778_3 phosphohydrolase (DHH superfamily) K07097 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 527.0
CMS1_k127_257778_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 405.0
CMS1_k127_257778_5 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 323.0
CMS1_k127_257778_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000001955 188.0
CMS1_k127_257778_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000033 139.0
CMS1_k127_257778_8 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000002805 109.0
CMS1_k127_2617485_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K17050 - - 0.0 1752.0
CMS1_k127_2617485_1 4Fe-4S dicluster domain K17051 - - 2.539e-228 708.0
CMS1_k127_2617485_10 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009368 264.0
CMS1_k127_2617485_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000003483 241.0
CMS1_k127_2617485_12 - - - - 0.000000000000000000000000000000000000000000003762 166.0
CMS1_k127_2617485_13 Belongs to the UPF0250 family - - - 0.00000000000000000000000000002258 120.0
CMS1_k127_2617485_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 531.0
CMS1_k127_2617485_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 531.0
CMS1_k127_2617485_4 Cytochrome c-552 DMSO reductase-like, heme-binding domain K17052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 471.0
CMS1_k127_2617485_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 449.0
CMS1_k127_2617485_6 General glycosylation pathway protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 314.0
CMS1_k127_2617485_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 310.0
CMS1_k127_2617485_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 287.0
CMS1_k127_2617485_9 Nitrate reductase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002691 275.0
CMS1_k127_2714971_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1307.0
CMS1_k127_2714971_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1233.0
CMS1_k127_2714971_10 Amidase K01457 - 3.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 599.0
CMS1_k127_2714971_11 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 588.0
CMS1_k127_2714971_12 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 554.0
CMS1_k127_2714971_13 Belongs to the UPF0061 (SELO) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 559.0
CMS1_k127_2714971_14 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 554.0
CMS1_k127_2714971_15 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 498.0
CMS1_k127_2714971_16 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 498.0
CMS1_k127_2714971_17 Cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 486.0
CMS1_k127_2714971_18 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 463.0
CMS1_k127_2714971_19 phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 451.0
CMS1_k127_2714971_2 GTP-binding protein K06207 - - 0.0 1062.0
CMS1_k127_2714971_20 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 458.0
CMS1_k127_2714971_21 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 449.0
CMS1_k127_2714971_22 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 445.0
CMS1_k127_2714971_23 ATP-binding protein K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 389.0
CMS1_k127_2714971_24 ABC transporter permease K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 360.0
CMS1_k127_2714971_25 (EAL) domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 370.0
CMS1_k127_2714971_26 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 330.0
CMS1_k127_2714971_27 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 319.0
CMS1_k127_2714971_28 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin K00477 - 1.14.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 313.0
CMS1_k127_2714971_29 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 306.0
CMS1_k127_2714971_3 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.088e-264 825.0
CMS1_k127_2714971_30 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 306.0
CMS1_k127_2714971_31 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 292.0
CMS1_k127_2714971_32 PhoU family K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 285.0
CMS1_k127_2714971_33 Belongs to the NadC ModD family K03813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004966 270.0
CMS1_k127_2714971_34 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000008377 259.0
CMS1_k127_2714971_35 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002671 259.0
CMS1_k127_2714971_36 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001546 251.0
CMS1_k127_2714971_37 COGs COG2454 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006474 256.0
CMS1_k127_2714971_38 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004608 251.0
CMS1_k127_2714971_39 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001157 252.0
CMS1_k127_2714971_4 Receptor - - - 6.833e-238 744.0
CMS1_k127_2714971_40 CMP dCMP deaminase K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000000000000001993 238.0
CMS1_k127_2714971_41 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004044 232.0
CMS1_k127_2714971_42 N-terminal domain of molybdenum-binding protein K02019 - - 0.00000000000000000000000000000000000000000000000000000000000000000005932 241.0
CMS1_k127_2714971_43 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000001405 212.0
CMS1_k127_2714971_44 amidase activity K01457 - 3.5.1.54 0.000000000000000000000000000000000000000000000000000000000003574 210.0
CMS1_k127_2714971_45 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000005531 203.0
CMS1_k127_2714971_46 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000002335 203.0
CMS1_k127_2714971_47 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000000000000000000000000000000000000000007546 187.0
CMS1_k127_2714971_48 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000003666 184.0
CMS1_k127_2714971_49 - - - - 0.0000000000000000000000000000000000000000000000003669 181.0
CMS1_k127_2714971_5 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 3.151e-225 717.0
CMS1_k127_2714971_50 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000000000000005272 153.0
CMS1_k127_2714971_51 Dinitrogenase iron-molybdenum cofactor biosynthesis protein K02596 - - 0.0000000000000000000000000000000000002261 144.0
CMS1_k127_2714971_52 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000000007694 134.0
CMS1_k127_2714971_53 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000001097 142.0
CMS1_k127_2714971_54 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000004809 132.0
CMS1_k127_2714971_55 - - - - 0.0000000000000000000000000002108 118.0
CMS1_k127_2714971_57 Transcriptional regulator, ModE family K02019 - - 0.00000000000000000000000002878 113.0
CMS1_k127_2714971_58 MOSC domain - - - 0.00000000000000000000000642 108.0
CMS1_k127_2714971_59 molybdate ion transport K02017,K06857 - 3.6.3.29,3.6.3.55 0.0000000000000000000001286 103.0
CMS1_k127_2714971_6 phosphate transporter K03306 - - 1.356e-215 682.0
CMS1_k127_2714971_60 Belongs to the glutaminase family K01425 - 3.5.1.2 0.0000000000000000000003046 97.0
CMS1_k127_2714971_61 TOBE domain - - - 0.0000000000000000000005088 102.0
CMS1_k127_2714971_62 lipoprotein - - - 0.000000000000000001022 90.0
CMS1_k127_2714971_64 pyrroloquinoline quinone binding - - - 0.000000000000003052 79.0
CMS1_k127_2714971_66 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000846 56.0
CMS1_k127_2714971_7 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 3.323e-199 628.0
CMS1_k127_2714971_8 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 604.0
CMS1_k127_2714971_9 - K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 603.0
CMS1_k127_2748492_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.003e-291 899.0
CMS1_k127_2748492_1 PFAM Alpha amylase, catalytic K00690 - 2.4.1.7 1.765e-239 753.0
CMS1_k127_2748492_10 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 340.0
CMS1_k127_2748492_11 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 338.0
CMS1_k127_2748492_12 hydroxypyruvate reductase K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 327.0
CMS1_k127_2748492_13 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001946 273.0
CMS1_k127_2748492_14 mannosylglycerate metabolic process K05947,K07026,K15918 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,2.7.1.31,3.1.3.70 0.00000000000000000000000000000000000000000000000000000004091 220.0
CMS1_k127_2748492_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000005812 200.0
CMS1_k127_2748492_16 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000001348 190.0
CMS1_k127_2748492_17 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000000005659 176.0
CMS1_k127_2748492_18 Belongs to the ATPase B chain family K02109 - - 0.00000000000000000000000000000000000000000000004941 173.0
CMS1_k127_2748492_19 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000128 171.0
CMS1_k127_2748492_2 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 589.0
CMS1_k127_2748492_20 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000000000002827 164.0
CMS1_k127_2748492_21 - - - - 0.000000000000000000000000000000000000000000884 160.0
CMS1_k127_2748492_22 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000000000003922 151.0
CMS1_k127_2748492_3 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 541.0
CMS1_k127_2748492_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 520.0
CMS1_k127_2748492_5 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 478.0
CMS1_k127_2748492_6 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 467.0
CMS1_k127_2748492_7 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 441.0
CMS1_k127_2748492_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 414.0
CMS1_k127_2748492_9 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 396.0
CMS1_k127_2754512_0 Cysteine desulfurase K04487 - 2.8.1.7 5.095e-237 736.0
CMS1_k127_2754512_1 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 2.528e-222 699.0
CMS1_k127_2754512_10 - - - - 0.00000001192 64.0
CMS1_k127_2754512_2 Mg chelatase-related protein K07391 - - 4.531e-209 660.0
CMS1_k127_2754512_3 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 592.0
CMS1_k127_2754512_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 576.0
CMS1_k127_2754512_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 351.0
CMS1_k127_2754512_6 GTP cyclohydrolase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 325.0
CMS1_k127_2754512_7 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K05910 - 1.11.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000008277 258.0
CMS1_k127_2754512_8 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000001283 226.0
CMS1_k127_2754512_9 YceI-like domain - - - 0.000000000000000000000000000000000000000000000002911 179.0
CMS1_k127_2787308_0 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains K02584 - - 1.159e-265 827.0
CMS1_k127_2787308_1 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 5.116e-229 723.0
CMS1_k127_2787308_10 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 396.0
CMS1_k127_2787308_11 AhpC/TSA family K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001126 277.0
CMS1_k127_2787308_12 TIGRFAM SagB-type dehydrogenase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004412 286.0
CMS1_k127_2787308_13 Low-potential electron donor to a number of redox enzymes K03839 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 271.0
CMS1_k127_2787308_14 Nitrogen fixation protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005528 228.0
CMS1_k127_2787308_15 Dinitrogenase iron-molybdenum cofactor biosynthesis protein K02596 - - 0.000000000000000000000000000000000000000000000000000000000000000635 223.0
CMS1_k127_2787308_16 Nitrogen fixation protein NifW K02595 - - 0.000000000000000000000000000000000000000000000000000000000003171 209.0
CMS1_k127_2787308_17 - - - - 0.00000000000000000000000000000000000000000000000000000088 199.0
CMS1_k127_2787308_18 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000001243 190.0
CMS1_k127_2787308_19 Ferredoxin - - - 0.000000000000000000000000000000000000000000000001165 178.0
CMS1_k127_2787308_2 Belongs to the NifD NifK NifE NifN family K02592 - - 5.402e-221 691.0
CMS1_k127_2787308_20 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000001903 159.0
CMS1_k127_2787308_21 Belongs to the ArsC family - - - 0.0000000000000000000000000000000001769 140.0
CMS1_k127_2787308_22 NifQ K15790 - - 0.0000000000000000000000000000000004425 134.0
CMS1_k127_2787308_23 Ferredoxin - - - 0.00000000000000000000000000001788 119.0
CMS1_k127_2787308_24 - - - - 0.000000000000000000000111 100.0
CMS1_k127_2787308_25 nitrogen fixation protein FixT K02593 - - 0.0000000000000000000001121 98.0
CMS1_k127_2787308_26 NifZ domain K02597 - - 0.00000000000000000002871 95.0
CMS1_k127_2787308_28 - - - - 0.000000000448 69.0
CMS1_k127_2787308_3 Metallo-beta-lactamase superfamily K22405 - 1.6.3.4 2.49e-220 689.0
CMS1_k127_2787308_4 cofactor biosynthesis protein NifE K02587 - - 1.435e-213 665.0
CMS1_k127_2787308_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 8.117e-212 665.0
CMS1_k127_2787308_6 COG0714 MoxR-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 543.0
CMS1_k127_2787308_7 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 517.0
CMS1_k127_2787308_8 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 472.0
CMS1_k127_2787308_9 Putative metallopeptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008507 428.0
CMS1_k127_2795959_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1298.0
CMS1_k127_2795959_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 0.0 1174.0
CMS1_k127_2795959_10 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.972e-217 679.0
CMS1_k127_2795959_11 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.843e-207 651.0
CMS1_k127_2795959_12 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 1.066e-206 649.0
CMS1_k127_2795959_13 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 1.983e-205 645.0
CMS1_k127_2795959_14 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 1.395e-195 620.0
CMS1_k127_2795959_15 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 6.658e-195 612.0
CMS1_k127_2795959_16 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 618.0
CMS1_k127_2795959_17 arsenite transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 583.0
CMS1_k127_2795959_18 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008509 574.0
CMS1_k127_2795959_19 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 535.0
CMS1_k127_2795959_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1039.0
CMS1_k127_2795959_20 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 521.0
CMS1_k127_2795959_21 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 469.0
CMS1_k127_2795959_22 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 457.0
CMS1_k127_2795959_23 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 452.0
CMS1_k127_2795959_24 Sodium calcium exchanger membrane K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 454.0
CMS1_k127_2795959_25 lytic murein transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 459.0
CMS1_k127_2795959_26 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 447.0
CMS1_k127_2795959_27 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 423.0
CMS1_k127_2795959_28 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 422.0
CMS1_k127_2795959_29 lytic murein transglycosylase K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 421.0
CMS1_k127_2795959_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1031.0
CMS1_k127_2795959_30 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 412.0
CMS1_k127_2795959_31 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 395.0
CMS1_k127_2795959_32 hydrolase, TatD K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 385.0
CMS1_k127_2795959_33 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 359.0
CMS1_k127_2795959_34 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 361.0
CMS1_k127_2795959_35 Subtilisin-like serine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 351.0
CMS1_k127_2795959_36 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 343.0
CMS1_k127_2795959_37 Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 344.0
CMS1_k127_2795959_38 phage repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 318.0
CMS1_k127_2795959_39 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 316.0
CMS1_k127_2795959_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.576e-317 980.0
CMS1_k127_2795959_40 Imidazoleglycerol-phosphate dehydratase K01089,K01693 - 3.1.3.15,4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 300.0
CMS1_k127_2795959_41 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 300.0
CMS1_k127_2795959_42 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 303.0
CMS1_k127_2795959_43 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 296.0
CMS1_k127_2795959_44 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 291.0
CMS1_k127_2795959_45 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002405 285.0
CMS1_k127_2795959_46 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005743 278.0
CMS1_k127_2795959_47 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008228 269.0
CMS1_k127_2795959_48 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001553 270.0
CMS1_k127_2795959_49 ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005418 265.0
CMS1_k127_2795959_5 PFAM Acyl-CoA dehydrogenase, C-terminal domain K06445 - - 6.305e-251 797.0
CMS1_k127_2795959_50 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002246 271.0
CMS1_k127_2795959_51 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006529 264.0
CMS1_k127_2795959_52 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000001686 243.0
CMS1_k127_2795959_53 acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000001251 229.0
CMS1_k127_2795959_54 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001628 218.0
CMS1_k127_2795959_55 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000000000000000000000005022 217.0
CMS1_k127_2795959_56 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000003558 209.0
CMS1_k127_2795959_57 G T U mismatch-specific DNA glycosylase - - - 0.00000000000000000000000000000000000000000000000000000002076 201.0
CMS1_k127_2795959_58 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000001317 198.0
CMS1_k127_2795959_59 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000001241 186.0
CMS1_k127_2795959_6 penicillin-binding protein K05515 - 3.4.16.4 5.767e-248 778.0
CMS1_k127_2795959_60 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000003179 179.0
CMS1_k127_2795959_61 TraB family K09973 - - 0.000000000000000000000000000000000000000000000008394 182.0
CMS1_k127_2795959_62 Lipopolysaccharide transport periplasmic protein lpta K09774 - - 0.0000000000000000000000000000000000000000000424 165.0
CMS1_k127_2795959_63 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000000000000000000000000000000000001378 147.0
CMS1_k127_2795959_64 - - - - 0.00000000000000000000000000000000000004709 150.0
CMS1_k127_2795959_65 hmm pf01863 K07043 - - 0.0000000000000000000000000000000000002878 149.0
CMS1_k127_2795959_66 YGGT family K02221 - - 0.00000000000000000000000000000000005248 136.0
CMS1_k127_2795959_68 Gluconate 2-dehydrogenase subunit 3 - - - 0.0000000000000000000000000000001089 130.0
CMS1_k127_2795959_69 Cytochrome c - - - 0.0000000000000000000000000000003241 125.0
CMS1_k127_2795959_7 Oxidoreductase K06151 - 1.1.99.3 2.135e-244 766.0
CMS1_k127_2795959_70 - - - - 0.0000000000000000000000000000003397 129.0
CMS1_k127_2795959_72 Protein of unknown function (DUF504) - - - 0.0000000000000000000000004908 107.0
CMS1_k127_2795959_73 Chlorite dismutase - - - 0.000000000000000000000004121 107.0
CMS1_k127_2795959_74 - - - - 0.000000000000000000575 89.0
CMS1_k127_2795959_75 - - - - 0.00000000000000004905 82.0
CMS1_k127_2795959_78 DnaJ domain-containing protein K14002 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005829,GO:0006457,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0006986,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0012505,GO:0019538,GO:0019941,GO:0030163,GO:0030433,GO:0030544,GO:0031072,GO:0031974,GO:0033554,GO:0034620,GO:0034975,GO:0034976,GO:0035966,GO:0035967,GO:0036503,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:0051087,GO:0051603,GO:0051716,GO:0070013,GO:0070887,GO:0071310,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901698 - 0.000008247 51.0
CMS1_k127_2795959_8 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.193e-237 737.0
CMS1_k127_2795959_80 SpoU rRNA Methylase family - - - 0.0001315 44.0
CMS1_k127_2795959_9 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 8.614e-223 696.0
CMS1_k127_2842331_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 2.395e-225 708.0
CMS1_k127_2842331_1 Ecdysteroid kinase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 438.0
CMS1_k127_2842331_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 353.0
CMS1_k127_2842331_3 Anhydro-N-acetylmuramic acid kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 333.0
CMS1_k127_2842331_4 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 311.0
CMS1_k127_2842331_5 conserved protein UCP016719 - - - 0.0000000000000000000000000000000000000000000000002319 179.0
CMS1_k127_2842331_6 SpoIIAA-like - - - 0.0000000000000000000000000000000000000003406 152.0
CMS1_k127_2842331_7 - - - - 0.0000000000007562 72.0
CMS1_k127_2842331_8 COG1309 Transcriptional regulator - - - 0.00006045 46.0
CMS1_k127_2884290_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.05e-199 626.0
CMS1_k127_2884290_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 361.0
CMS1_k127_2884290_2 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002021 246.0
CMS1_k127_2884290_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000002747 78.0
CMS1_k127_2895411_0 2-acylglycerophosphoethanolamine acyltransferase K05939 - 2.3.1.40,6.2.1.20 6.856e-197 632.0
CMS1_k127_2895411_1 Pfam Transposase IS66 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 374.0
CMS1_k127_2895411_10 - - - - 0.00000000000000000000000000001081 124.0
CMS1_k127_2895411_11 Domain of unknown function (DUF1851) - - - 0.00000000000000000000000000001582 123.0
CMS1_k127_2895411_12 - - - - 0.00000000000000000000002374 111.0
CMS1_k127_2895411_13 Protein of unknown function (DUF2892) - - - 0.000000000000000000002139 94.0
CMS1_k127_2895411_14 Ppx GppA phosphatase - - - 0.0000003333 59.0
CMS1_k127_2895411_2 Di-haem cytochrome c peroxidase - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 339.0
CMS1_k127_2895411_3 PFAM Flavin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 316.0
CMS1_k127_2895411_4 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002016 273.0
CMS1_k127_2895411_5 Family of unknown function (DUF695) - - - 0.000000000000000000000000000000000000000000000000000003365 198.0
CMS1_k127_2895411_6 - - - - 0.0000000000000000000000000000000000000001086 157.0
CMS1_k127_2895411_7 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000004811 151.0
CMS1_k127_2895411_8 FMN binding - - - 0.000000000000000000000000000000000000008139 152.0
CMS1_k127_2895411_9 - - - - 0.000000000000000000000000000007849 124.0
CMS1_k127_2900019_0 Mitochondrial degradasome RNA helicase subunit C terminal K17675 - 3.6.4.13 1.75e-321 1010.0
CMS1_k127_2900019_1 Major facilitator superfamily K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 428.0
CMS1_k127_2900019_10 - - - - 0.00000005289 55.0
CMS1_k127_2900019_12 - - - - 0.0004857 43.0
CMS1_k127_2900019_2 mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 307.0
CMS1_k127_2900019_3 - - - - 0.000000000000000000000000000000000000000000000000008743 198.0
CMS1_k127_2900019_4 RDD family - - - 0.000000000000000000000000000000000000000000004311 170.0
CMS1_k127_2900019_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000000000001215 162.0
CMS1_k127_2900019_6 Protein of unknown function, DUF481 K07283 - - 0.000000000000000000000000000001074 133.0
CMS1_k127_2900019_7 Domain of unknown function (DUF309) - - - 0.000000000000000000000000000003963 123.0
CMS1_k127_2900019_9 - - - - 0.00000004211 54.0
CMS1_k127_2922788_0 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 291.0
CMS1_k127_2922788_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000798 240.0
CMS1_k127_2922788_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000000004434 231.0
CMS1_k127_2922788_3 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000002309 217.0
CMS1_k127_2922788_4 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000007659 203.0
CMS1_k127_2922788_5 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000005112 152.0
CMS1_k127_2922788_6 Sensors of blue-light using FAD - - - 0.000000000000000000000000000000000007936 151.0
CMS1_k127_2984130_0 UPF0313 protein - - - 0.0 1025.0
CMS1_k127_2984130_1 SpoU rRNA Methylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 366.0
CMS1_k127_2984130_2 protein conserved in bacteria K09973 - - 0.00000000000000000000000000002657 124.0
CMS1_k127_2984130_3 Tellurite resistance protein TehB - - - 0.00000000000000002725 81.0
CMS1_k127_3035207_0 phosphate-selective porin O and P - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 488.0
CMS1_k127_3035207_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 445.0
CMS1_k127_3035207_2 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000002653 236.0
CMS1_k127_3035207_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000003935 217.0
CMS1_k127_3035207_4 Histidine kinase K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000001751 175.0
CMS1_k127_3050889_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1095.0
CMS1_k127_3050889_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1073.0
CMS1_k127_3050889_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009168 265.0
CMS1_k127_3050889_11 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000008278 262.0
CMS1_k127_3050889_12 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000008049 203.0
CMS1_k127_3050889_13 Macro domain - - - 0.000000000000000000000000000000000000000000000000000001671 196.0
CMS1_k127_3050889_14 - - - - 0.0000000000000000000000000000000002217 134.0
CMS1_k127_3050889_15 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000205 131.0
CMS1_k127_3050889_16 PFAM peptidase C14 caspase catalytic subunit p20 - - - 0.00000000000000000000000001933 122.0
CMS1_k127_3050889_17 Histidine kinase K03407 - 2.7.13.3 0.00000000000000000000002946 110.0
CMS1_k127_3050889_18 Oxaloacetate decarboxylase, gamma chain K01573 - 4.1.1.3 0.00000000000000004049 83.0
CMS1_k127_3050889_19 ERAD pathway K14026 - - 0.0000000000001832 82.0
CMS1_k127_3050889_2 PFAM biotin lipoyl attachment domain-containing protein K01960 - 6.4.1.1 8.029e-300 927.0
CMS1_k127_3050889_20 Belongs to the universal stress protein A family - - - 0.0000000001438 72.0
CMS1_k127_3050889_21 Catalyzes the sodium-dependent transport of glutamate K03312 - - 0.0008134 46.0
CMS1_k127_3050889_3 molybdopterin oxidoreductase - - - 7.368e-227 719.0
CMS1_k127_3050889_4 COG1883 Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit K01572 - 4.1.1.3 3.387e-224 701.0
CMS1_k127_3050889_5 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 - 1.12.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 593.0
CMS1_k127_3050889_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 587.0
CMS1_k127_3050889_7 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 382.0
CMS1_k127_3050889_8 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 305.0
CMS1_k127_3115321_0 ATP-dependent CLP protease ATP-binding subunit K03694 - - 2.975e-273 858.0
CMS1_k127_3115321_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.866e-215 672.0
CMS1_k127_3115321_10 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 441.0
CMS1_k127_3115321_11 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 371.0
CMS1_k127_3115321_12 component I K01665 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 359.0
CMS1_k127_3115321_13 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007709 311.0
CMS1_k127_3115321_14 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 306.0
CMS1_k127_3115321_15 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000007978 252.0
CMS1_k127_3115321_16 Belongs to the beta-ketoacyl-ACP synthases family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004331 254.0
CMS1_k127_3115321_17 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000001996 235.0
CMS1_k127_3115321_18 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000287 214.0
CMS1_k127_3115321_19 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000006255 209.0
CMS1_k127_3115321_2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal - - - 4.103e-196 616.0
CMS1_k127_3115321_20 - - - - 0.000000000000000000000000000000000000000000000007006 176.0
CMS1_k127_3115321_21 (HIT) family - - - 0.0000000000000000000000000000000000000000000003448 169.0
CMS1_k127_3115321_22 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000001659 142.0
CMS1_k127_3115321_23 metal-binding, possibly nucleic acid-binding protein - - - 0.000000000000000000000000000001884 123.0
CMS1_k127_3115321_24 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000000001235 123.0
CMS1_k127_3115321_25 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000000001654 119.0
CMS1_k127_3115321_26 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000004619 104.0
CMS1_k127_3115321_3 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 604.0
CMS1_k127_3115321_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 539.0
CMS1_k127_3115321_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 530.0
CMS1_k127_3115321_6 Butirosin biosynthesis protein H, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 488.0
CMS1_k127_3115321_7 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 469.0
CMS1_k127_3115321_8 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 452.0
CMS1_k127_3115321_9 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 436.0
CMS1_k127_335497_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1191.0
CMS1_k127_335497_1 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 2.131e-270 839.0
CMS1_k127_335497_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 445.0
CMS1_k127_335497_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 369.0
CMS1_k127_335497_4 dna polymerase iii K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 307.0
CMS1_k127_335497_5 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000002316 180.0
CMS1_k127_3400454_0 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 608.0
CMS1_k127_3400454_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 377.0
CMS1_k127_3400454_2 amidase activity K03796 - - 0.00000000000000000000000000000000000008785 155.0
CMS1_k127_3400454_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000001391 120.0
CMS1_k127_3595602_0 PFAM Sulfatase K01130 - 3.1.6.1 5.166e-300 940.0
CMS1_k127_3595602_1 Peptidase s1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005133 476.0
CMS1_k127_3595602_10 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000000000000000000000000000002056 181.0
CMS1_k127_3595602_11 Membrane K08984 - - 0.00000000000000000000000000000000000005274 150.0
CMS1_k127_3595602_12 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000004994 139.0
CMS1_k127_3595602_13 SEC-C motif K09858 - - 0.0000000000000000000004288 96.0
CMS1_k127_3595602_14 Domain of unknown function (DUF4156) - - - 0.000000000001429 72.0
CMS1_k127_3595602_2 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 471.0
CMS1_k127_3595602_3 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 469.0
CMS1_k127_3595602_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 411.0
CMS1_k127_3595602_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 373.0
CMS1_k127_3595602_6 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 364.0
CMS1_k127_3595602_7 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 342.0
CMS1_k127_3595602_8 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000008442 178.0
CMS1_k127_3595602_9 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000000000001292 177.0
CMS1_k127_3610400_0 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 313.0
CMS1_k127_3610400_1 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 291.0
CMS1_k127_3610400_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000008353 150.0
CMS1_k127_3675092_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 564.0
CMS1_k127_3675092_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 495.0
CMS1_k127_3675092_10 ATP synthase B/B' CF(0) K02109 - - 0.0000004212 61.0
CMS1_k127_3675092_11 TIGRFAM F0F1-ATPase subunit K02116 - - 0.00003261 50.0
CMS1_k127_3675092_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 468.0
CMS1_k127_3675092_3 COGs COG4087 Soluble P-type ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000006592 224.0
CMS1_k127_3675092_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000002293 196.0
CMS1_k127_3675092_5 phosphohistidine phosphatase, SixA K08296 - - 0.000000000000000000000000000000000000000000002055 171.0
CMS1_k127_3675092_6 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000004748 121.0
CMS1_k127_3675092_7 ATP synthase K02115 - - 0.00000000000000004234 92.0
CMS1_k127_3675092_8 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.00000000005342 68.0
CMS1_k127_3675092_9 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.000000139 53.0
CMS1_k127_3702560_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 3.362e-241 769.0
CMS1_k127_3702560_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000001453 95.0
CMS1_k127_3702560_2 GGDEF EAL family protein - - - 0.000000000001177 72.0
CMS1_k127_372559_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 484.0
CMS1_k127_372559_1 COG0530 Ca2 Na antiporter K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 448.0
CMS1_k127_372559_10 sodium:proton antiporter activity K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 302.0
CMS1_k127_372559_11 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003095 274.0
CMS1_k127_372559_12 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001839 276.0
CMS1_k127_372559_13 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005966 273.0
CMS1_k127_372559_14 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002605 242.0
CMS1_k127_372559_15 MotA TolQ ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000003904 233.0
CMS1_k127_372559_16 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000001878 228.0
CMS1_k127_372559_17 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000000000000000000000000000000000000007162 224.0
CMS1_k127_372559_18 hmm pf01205 - - - 0.0000000000000000000000000000000000000000000000000000000001779 208.0
CMS1_k127_372559_19 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000001034 188.0
CMS1_k127_372559_2 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 441.0
CMS1_k127_372559_20 transport protein K03559 - - 0.0000000000000000000000000000000000000000000000004341 178.0
CMS1_k127_372559_21 Bacterial protein of unknown function (YtfJ_HI0045) K07109 - - 0.00000000000000000000000000000000000000000000001316 175.0
CMS1_k127_372559_22 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000139 176.0
CMS1_k127_372559_23 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000000006647 154.0
CMS1_k127_372559_24 peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000001016 147.0
CMS1_k127_372559_25 TonB C terminal K03832 - - 0.000000000000000000000000000000001717 139.0
CMS1_k127_372559_26 - - - - 0.0000000000000000000000000000001968 128.0
CMS1_k127_372559_27 Rhodanese-like domain - - - 0.00000000000000000000000001495 112.0
CMS1_k127_372559_28 OmpA-like transmembrane domain - - - 0.00000000000000000000008058 106.0
CMS1_k127_372559_29 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000001099 92.0
CMS1_k127_372559_3 Belongs to the TtcA family K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 415.0
CMS1_k127_372559_4 Protein of unknown function (DUF3137) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 377.0
CMS1_k127_372559_5 a g-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 376.0
CMS1_k127_372559_6 membrane K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 370.0
CMS1_k127_372559_7 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K18284 - 3.2.2.30,3.2.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 345.0
CMS1_k127_372559_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 325.0
CMS1_k127_372559_9 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 306.0
CMS1_k127_3742139_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.657e-258 802.0
CMS1_k127_3742139_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 495.0
CMS1_k127_3742139_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 319.0
CMS1_k127_3742139_3 - - - - 0.00000000000000000000000000000000000000000000001861 184.0
CMS1_k127_3774156_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 5.709e-300 943.0
CMS1_k127_3774156_1 Acts as a magnesium transporter K06213 - - 3.584e-216 678.0
CMS1_k127_3774156_10 Hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 457.0
CMS1_k127_3774156_11 polyphosphate kinase K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 434.0
CMS1_k127_3774156_12 Nucleotidyltransferase DNA polymerase involved in DNA repair K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 409.0
CMS1_k127_3774156_13 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 391.0
CMS1_k127_3774156_14 flavin adenine dinucleotide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 389.0
CMS1_k127_3774156_15 Archaea bacterial proteins of unknown function K06921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 334.0
CMS1_k127_3774156_16 CorA-like Mg2 transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 331.0
CMS1_k127_3774156_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 293.0
CMS1_k127_3774156_18 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 301.0
CMS1_k127_3774156_19 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008534 270.0
CMS1_k127_3774156_2 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 6.237e-210 661.0
CMS1_k127_3774156_20 Putative ATP-dependant zinc protease - - - 0.000000000000000000000000000000000000000000025 165.0
CMS1_k127_3774156_21 Ester cyclase - - - 0.00000000000000000000000000000000000000003263 155.0
CMS1_k127_3774156_22 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000003621 156.0
CMS1_k127_3774156_23 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000000001782 147.0
CMS1_k127_3774156_24 deoxyribonuclease I activity K01150 - 3.1.21.1 0.0000000000000000000000000000000008572 140.0
CMS1_k127_3774156_3 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 620.0
CMS1_k127_3774156_4 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 573.0
CMS1_k127_3774156_5 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 567.0
CMS1_k127_3774156_6 Belongs to the glutaminase family K01425 - 3.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 505.0
CMS1_k127_3774156_7 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 489.0
CMS1_k127_3774156_8 Belongs to the RimK family K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 485.0
CMS1_k127_3774156_9 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 484.0
CMS1_k127_3788694_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1377.0
CMS1_k127_3788694_1 Ammonium Transporter K03320 - - 5.455e-227 708.0
CMS1_k127_3788694_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 9.848e-210 655.0
CMS1_k127_3788694_3 Ammonium Transporter K03320 - - 8.167e-208 650.0
CMS1_k127_3788694_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 548.0
CMS1_k127_3788694_5 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 404.0
CMS1_k127_3788694_6 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 298.0
CMS1_k127_3788694_7 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000016 201.0
CMS1_k127_3788694_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000004202 96.0
CMS1_k127_3788694_9 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000001175 55.0
CMS1_k127_3798390_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 1.317e-226 716.0
CMS1_k127_3798390_1 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 312.0
CMS1_k127_3798390_2 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000000000000000000000000000000007075 176.0
CMS1_k127_3798390_3 Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000000008709 139.0
CMS1_k127_3798390_4 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000004851 66.0
CMS1_k127_3848390_0 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 1.488e-237 740.0
CMS1_k127_3848390_1 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 532.0
CMS1_k127_3848390_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 371.0
CMS1_k127_3848390_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001197 265.0
CMS1_k127_3848390_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000009085 223.0
CMS1_k127_3848390_5 Biopolymer transporter ExbB K03561 - - 0.0000000000000000000000000000000000000000000000000000008365 195.0
CMS1_k127_3848390_6 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000002979 171.0
CMS1_k127_3848390_7 biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000000003916 161.0
CMS1_k127_3848390_8 START domain - - - 0.0000000000000000000000000505 118.0
CMS1_k127_3848390_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000002022 97.0
CMS1_k127_3849650_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 616.0
CMS1_k127_3849650_1 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 465.0
CMS1_k127_3849650_2 competence protein K02237 - - 0.0000000000000003111 81.0
CMS1_k127_3876081_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 4.184e-218 683.0
CMS1_k127_3876081_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.446e-211 665.0
CMS1_k127_3876081_10 SCP / Tpx-1 / Ag5 / PR-1 / Sc7 family of extracellular domains. - - - 0.00000000000000000000000000000000000001625 150.0
CMS1_k127_3876081_11 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000008023 156.0
CMS1_k127_3876081_12 Heat shock protein DnaJ domain protein K06203,K07126 - - 0.00000000000000000000000000000000002148 137.0
CMS1_k127_3876081_13 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000007448 80.0
CMS1_k127_3876081_14 - - - - 0.00005735 51.0
CMS1_k127_3876081_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 565.0
CMS1_k127_3876081_3 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 520.0
CMS1_k127_3876081_4 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 466.0
CMS1_k127_3876081_5 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 332.0
CMS1_k127_3876081_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 334.0
CMS1_k127_3876081_7 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003848 254.0
CMS1_k127_3876081_8 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000000000000000006892 237.0
CMS1_k127_3876081_9 Transglutaminase-like superfamily K07184 - - 0.00000000000000000000000000000000000000000000000000000003637 219.0
CMS1_k127_3938451_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1083.0
CMS1_k127_3938451_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.777e-320 988.0
CMS1_k127_3938451_10 Histidine kinase K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 437.0
CMS1_k127_3938451_11 permease K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 434.0
CMS1_k127_3938451_12 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 410.0
CMS1_k127_3938451_13 response regulator K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 362.0
CMS1_k127_3938451_14 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 323.0
CMS1_k127_3938451_15 HAD-superfamily hydrolase, subfamily IIA K02566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 318.0
CMS1_k127_3938451_16 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 309.0
CMS1_k127_3938451_17 PFAM dUTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 296.0
CMS1_k127_3938451_18 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000995 282.0
CMS1_k127_3938451_19 Sugar-transfer associated ATP-grasp - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008904 257.0
CMS1_k127_3938451_2 Sulfatase-modifying factor enzyme 1 - - - 9.157e-283 885.0
CMS1_k127_3938451_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000002463 237.0
CMS1_k127_3938451_21 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000002482 196.0
CMS1_k127_3938451_22 cofactor binding K09979 - - 0.00000000000000000000000000000000000000000005637 164.0
CMS1_k127_3938451_23 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000007912 153.0
CMS1_k127_3938451_24 GDSL-like lipase acylhydrolase - - - 0.000000000000000000000000008989 116.0
CMS1_k127_3938451_25 iron ion homeostasis K04758 - - 0.00000000000000000004554 92.0
CMS1_k127_3938451_26 - - - - 0.00000000000000008436 88.0
CMS1_k127_3938451_27 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000007407 76.0
CMS1_k127_3938451_28 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000008375 69.0
CMS1_k127_3938451_29 Membrane - - - 0.00000000002262 70.0
CMS1_k127_3938451_3 Belongs to the DEAD box helicase family K05592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 7.056e-237 741.0
CMS1_k127_3938451_30 - - - - 0.0000000004153 63.0
CMS1_k127_3938451_31 - - - - 0.0000000006675 66.0
CMS1_k127_3938451_32 - - - - 0.0002651 49.0
CMS1_k127_3938451_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 2.984e-209 659.0
CMS1_k127_3938451_5 Chorismate mutase prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 577.0
CMS1_k127_3938451_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 526.0
CMS1_k127_3938451_7 Cache domain K02480,K03406 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 492.0
CMS1_k127_3938451_8 Aminotransferase, class I K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 476.0
CMS1_k127_3938451_9 DNA recombination protein K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 476.0
CMS1_k127_3944687_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2415.0
CMS1_k127_3944687_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1580.0
CMS1_k127_3944687_10 RecO N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 300.0
CMS1_k127_3944687_11 PFAM Glycosyl transferase family 2 K00721,K00786 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 293.0
CMS1_k127_3944687_12 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 286.0
CMS1_k127_3944687_13 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002248 284.0
CMS1_k127_3944687_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003054 278.0
CMS1_k127_3944687_15 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000002558 228.0
CMS1_k127_3944687_16 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000004522 222.0
CMS1_k127_3944687_17 MCRA family - - - 0.00000000000000000000000000000000000000000000000000000000001264 209.0
CMS1_k127_3944687_18 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000164 214.0
CMS1_k127_3944687_19 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000003413 199.0
CMS1_k127_3944687_2 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 3.114e-254 788.0
CMS1_k127_3944687_20 MCRA family - - - 0.0000000000000000000000000000000000000000000007055 167.0
CMS1_k127_3944687_21 - - - - 0.00000000000000000000000000000000000000000002443 167.0
CMS1_k127_3944687_22 Nucleoside 2-deoxyribosyltransferase K08728 - 2.4.2.6 0.00000000000000000000000000000000000000001836 159.0
CMS1_k127_3944687_23 DnaK suppressor protein K06204 - - 0.00000000000000000000000000000000000000007246 153.0
CMS1_k127_3944687_24 Domain of unknown function (DUF4395) - - - 0.000000000000000000000000000000001333 135.0
CMS1_k127_3944687_25 Myosin-crossreactive antigen K10254 - 4.2.1.53 0.000000000000000000000000000000006079 130.0
CMS1_k127_3944687_26 - - - - 0.0000000000000000000000000003885 129.0
CMS1_k127_3944687_27 MCRA family - - - 0.0000000000000000000000000007769 114.0
CMS1_k127_3944687_28 - - - - 0.00000000000000000000000002334 119.0
CMS1_k127_3944687_29 - - - - 0.0000000000000000000002672 100.0
CMS1_k127_3944687_3 DNA RNA helicase - - - 1.361e-221 723.0
CMS1_k127_3944687_30 - - - - 0.0000000000000000000997 101.0
CMS1_k127_3944687_31 Histidine kinase K03407 - 2.7.13.3 0.0000000000276 71.0
CMS1_k127_3944687_32 GtrA-like protein - - - 0.0000000004959 65.0
CMS1_k127_3944687_33 - - - - 0.000000001977 70.0
CMS1_k127_3944687_4 dehydrogenase K08325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 604.0
CMS1_k127_3944687_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 492.0
CMS1_k127_3944687_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 457.0
CMS1_k127_3944687_7 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 347.0
CMS1_k127_3944687_8 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 317.0
CMS1_k127_3944687_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 315.0
CMS1_k127_3963181_0 Molecular chaperone. Has ATPase activity K04079 - - 1.322e-315 977.0
CMS1_k127_3963181_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 9.157e-197 621.0
CMS1_k127_3963181_10 cytochrome c biogenesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 312.0
CMS1_k127_3963181_11 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002286 262.0
CMS1_k127_3963181_12 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000107 240.0
CMS1_k127_3963181_13 Peptidase A24 K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000005819 246.0
CMS1_k127_3963181_14 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000000000000000000000000000000002052 225.0
CMS1_k127_3963181_15 Redox-active disulfide protein - - - 0.000000000000000000000000002165 121.0
CMS1_k127_3963181_16 Thioredoxin K03671 - - 0.0000000000000000001688 93.0
CMS1_k127_3963181_17 Protein of unknown function (DUF2798) - - - 0.00000000000007886 72.0
CMS1_k127_3963181_18 FtsZ-dependent cytokinesis - GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.000001045 55.0
CMS1_k127_3963181_19 SNARE associated Golgi protein - - - 0.0001627 48.0
CMS1_k127_3963181_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 606.0
CMS1_k127_3963181_3 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 582.0
CMS1_k127_3963181_4 Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) K00557 - 2.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 488.0
CMS1_k127_3963181_5 Permease, YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 411.0
CMS1_k127_3963181_6 permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 409.0
CMS1_k127_3963181_7 Co Zn Cd efflux system component K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 359.0
CMS1_k127_3963181_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 342.0
CMS1_k127_3963181_9 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 323.0
CMS1_k127_4021211_0 Na Pi-cotransporter K03324 - - 1.817e-197 632.0
CMS1_k127_4021211_1 SpoIIAA-like - - - 0.0000001945 58.0
CMS1_k127_4091609_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00367,K00372,K08356 - 1.20.2.1,1.20.9.1,1.7.7.2 4.254e-290 904.0
CMS1_k127_4091609_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K15576 - - 5.634e-269 832.0
CMS1_k127_4091609_2 ABC transporter K15555,K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 450.0
CMS1_k127_4091609_3 COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 435.0
CMS1_k127_4091609_4 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000000000007343 215.0
CMS1_k127_4091609_5 - - - - 0.000000000000000000000000000000003201 133.0
CMS1_k127_4121521_0 Receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 482.0
CMS1_k127_4121521_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 441.0
CMS1_k127_4121521_10 von Willebrand factor, type A K07114 - - 0.0000000000000000007396 96.0
CMS1_k127_4121521_11 - - - - 0.0000000004015 66.0
CMS1_k127_4121521_2 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 362.0
CMS1_k127_4121521_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 317.0
CMS1_k127_4121521_4 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 306.0
CMS1_k127_4121521_5 Oxygen tolerance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009545 314.0
CMS1_k127_4121521_6 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004594 276.0
CMS1_k127_4121521_7 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005883 248.0
CMS1_k127_4121521_8 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000000000001322 203.0
CMS1_k127_4121521_9 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000008627 117.0
CMS1_k127_4522004_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 1.915e-273 846.0
CMS1_k127_4522004_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 6.742e-256 792.0
CMS1_k127_4522004_10 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 588.0
CMS1_k127_4522004_11 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 579.0
CMS1_k127_4522004_12 domain protein K09944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 569.0
CMS1_k127_4522004_13 Belongs to the AAA ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 554.0
CMS1_k127_4522004_14 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 519.0
CMS1_k127_4522004_15 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 489.0
CMS1_k127_4522004_16 Archaea bacterial proteins of unknown function K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 466.0
CMS1_k127_4522004_17 GH3 auxin-responsive promoter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 457.0
CMS1_k127_4522004_18 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 451.0
CMS1_k127_4522004_19 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 428.0
CMS1_k127_4522004_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 1.849e-244 758.0
CMS1_k127_4522004_20 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 407.0
CMS1_k127_4522004_21 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 378.0
CMS1_k127_4522004_22 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 374.0
CMS1_k127_4522004_23 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 369.0
CMS1_k127_4522004_24 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 366.0
CMS1_k127_4522004_25 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 361.0
CMS1_k127_4522004_26 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 367.0
CMS1_k127_4522004_27 RNase H K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 339.0
CMS1_k127_4522004_28 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006566 327.0
CMS1_k127_4522004_29 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 332.0
CMS1_k127_4522004_3 anthranilate synthase component K01657 - 4.1.3.27 1.222e-226 709.0
CMS1_k127_4522004_30 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 317.0
CMS1_k127_4522004_31 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 290.0
CMS1_k127_4522004_32 Dehydratase family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000005285 253.0
CMS1_k127_4522004_33 Belongs to the Fur family K03711 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000002204 241.0
CMS1_k127_4522004_35 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000000000000000000000003945 232.0
CMS1_k127_4522004_36 - - - - 0.0000000000000000000000000000000000000000000000000000000001336 209.0
CMS1_k127_4522004_37 - - - - 0.0000000000000000000000000000000000000000000000000000000004057 210.0
CMS1_k127_4522004_38 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.00000000000000000000000000000000000000000000000000000003563 199.0
CMS1_k127_4522004_39 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000001757 201.0
CMS1_k127_4522004_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 4.149e-213 666.0
CMS1_k127_4522004_40 ketosteroid isomerase - - - 0.00000000000000000000000000000000000000000000000006424 184.0
CMS1_k127_4522004_41 - - - - 0.0000000000000000000000000000000000000000000000007376 189.0
CMS1_k127_4522004_42 Protein of unknown function (DUF3584) - - - 0.000000000000000000000000000000000000000000000001794 198.0
CMS1_k127_4522004_43 Domain of unknown function (DUF1882) - - - 0.0000000000000000000000000000000000000007415 154.0
CMS1_k127_4522004_44 ArsC family - - - 0.000000000000000000000000000000000000003072 148.0
CMS1_k127_4522004_45 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000009105 149.0
CMS1_k127_4522004_46 - - - - 0.00000000000000000000000000000000000005573 145.0
CMS1_k127_4522004_47 PAP2 superfamily - - - 0.0000000000000000000000000000000000021 145.0
CMS1_k127_4522004_48 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000001436 138.0
CMS1_k127_4522004_49 Nitroreductase family - - - 0.000000000000000000000000000000006198 134.0
CMS1_k127_4522004_5 Elongator protein 3, MiaB family, Radical SAM - - - 2.7e-211 664.0
CMS1_k127_4522004_50 - - - - 0.0000000000000000000000000000000125 130.0
CMS1_k127_4522004_51 Cell division protein K03591,K03749 - - 0.0000000000000000000000000000008164 131.0
CMS1_k127_4522004_53 -acetyltransferase K06975 - - 0.0000000000000000000175 94.0
CMS1_k127_4522004_54 - - - - 0.000000000000003698 77.0
CMS1_k127_4522004_55 Protein of unknown function (DUF3293) - - - 0.000000000125 68.0
CMS1_k127_4522004_6 Elongator protein 3, MiaB family, Radical SAM - - - 3.83e-209 657.0
CMS1_k127_4522004_7 MiaB-like tRNA modifying enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 604.0
CMS1_k127_4522004_8 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 605.0
CMS1_k127_4522004_9 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 594.0
CMS1_k127_45323_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 2.553e-213 676.0
CMS1_k127_45323_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 578.0
CMS1_k127_45323_10 membrane K08973 - - 0.00000000000000000000000000000000000000000000000000000000000000002831 227.0
CMS1_k127_45323_11 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000003857 235.0
CMS1_k127_45323_12 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000002027 205.0
CMS1_k127_45323_13 MltA-interacting MipA family protein K07274 - - 0.00000000000000000000000000000000000000000000000000002729 194.0
CMS1_k127_45323_14 Sigma 54 modulation protein / S30EA ribosomal protein K05808 - - 0.000000000000000000000000000000000000000916 150.0
CMS1_k127_45323_15 - - - - 0.0000000000002371 71.0
CMS1_k127_45323_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 559.0
CMS1_k127_45323_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 482.0
CMS1_k127_45323_4 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 462.0
CMS1_k127_45323_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 370.0
CMS1_k127_45323_6 membrane K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 331.0
CMS1_k127_45323_7 mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 338.0
CMS1_k127_45323_8 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000008106 242.0
CMS1_k127_45323_9 DnaJ domain protein K05801 - - 0.000000000000000000000000000000000000000000000000000000000000000003356 235.0
CMS1_k127_4539585_0 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 2.873e-215 677.0
CMS1_k127_4539585_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004457 281.0
CMS1_k127_4539585_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000104 272.0
CMS1_k127_4539585_3 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000000000000000000000000008542 174.0
CMS1_k127_4539585_4 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000000004745 140.0
CMS1_k127_4539585_5 Kinase D-interacting substrate K12460 GO:0000186,GO:0001932,GO:0001934,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005768,GO:0005770,GO:0005829,GO:0007154,GO:0007165,GO:0007166,GO:0007275,GO:0007399,GO:0008150,GO:0009719,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010562,GO:0010604,GO:0010646,GO:0010647,GO:0010720,GO:0010975,GO:0010976,GO:0012505,GO:0019207,GO:0019220,GO:0019222,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0019904,GO:0022008,GO:0023051,GO:0023052,GO:0023056,GO:0030154,GO:0030165,GO:0030234,GO:0031323,GO:0031325,GO:0031344,GO:0031346,GO:0031399,GO:0031401,GO:0031410,GO:0031982,GO:0032147,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032991,GO:0033674,GO:0038179,GO:0038180,GO:0042221,GO:0042325,GO:0042327,GO:0043085,GO:0043226,GO:0043227,GO:0043229,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043549,GO:0044093,GO:0044424,GO:0044444,GO:0044464,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045859,GO:0045860,GO:0045937,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051174,GO:0051239,GO:0051240,GO:0051246,GO:0051247,GO:0051338,GO:0051347,GO:0051716,GO:0051960,GO:0051962,GO:0060255,GO:0060284,GO:0065007,GO:0065009,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071900,GO:0071902,GO:0080090,GO:0097708,GO:0098772,GO:0120035,GO:1902531,GO:1902533,GO:1990089,GO:1990090,GO:2000026 - 0.0000000000000000000000000002438 123.0
CMS1_k127_4539585_6 phage repressor - - - 0.00000000000000000001152 96.0
CMS1_k127_4539585_7 Nitrogen regulatory protein P-II K04751 - - 0.0002496 43.0
CMS1_k127_4555715_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1822.0
CMS1_k127_4555715_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.831e-282 875.0
CMS1_k127_4555715_10 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 422.0
CMS1_k127_4555715_11 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034,K12370 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 399.0
CMS1_k127_4555715_12 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 377.0
CMS1_k127_4555715_13 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 366.0
CMS1_k127_4555715_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 330.0
CMS1_k127_4555715_15 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 326.0
CMS1_k127_4555715_16 AI-2E family transporter K11744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 302.0
CMS1_k127_4555715_17 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006325 270.0
CMS1_k127_4555715_18 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000002333 244.0
CMS1_k127_4555715_19 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003305 269.0
CMS1_k127_4555715_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.356e-223 697.0
CMS1_k127_4555715_20 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000002201 233.0
CMS1_k127_4555715_21 - - - - 0.000000000000000000000000000000000000000000000000000000000002258 214.0
CMS1_k127_4555715_22 MltA-interacting protein MipA K07274 - - 0.000000000000000000000000000000000000000000000000000000002839 209.0
CMS1_k127_4555715_23 Transcriptional regulator K13640 - - 0.00000000000000000000000000000000000000000000000000000007429 197.0
CMS1_k127_4555715_24 Rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000000000000002229 196.0
CMS1_k127_4555715_25 - - - - 0.000000000000000000000000000000000000000000000000001396 187.0
CMS1_k127_4555715_26 integral membrane protein - - - 0.000000000000000000000000000000000000000000000004007 181.0
CMS1_k127_4555715_27 L-threonylcarbamoyladenylate synthase - - - 0.00000000000000000000000000000000002421 140.0
CMS1_k127_4555715_28 Membrane - - - 0.000000000000000000000000000002627 128.0
CMS1_k127_4555715_29 Polysaccharide deacetylase - - - 0.00000000000000000000000000009591 135.0
CMS1_k127_4555715_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.677e-197 622.0
CMS1_k127_4555715_30 membrane - - - 0.0000000000526 64.0
CMS1_k127_4555715_31 - - - - 0.000000308 53.0
CMS1_k127_4555715_4 Glutathionylspermidine synthase - - - 2.072e-195 614.0
CMS1_k127_4555715_5 rod shape-determining protein mreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 602.0
CMS1_k127_4555715_6 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 601.0
CMS1_k127_4555715_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 553.0
CMS1_k127_4555715_8 Co-chaperone-curved DNA binding protein A K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 435.0
CMS1_k127_4555715_9 outer membrane porin, OprD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 435.0
CMS1_k127_45678_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1137.0
CMS1_k127_45678_1 RNA binding S1 domain protein K06959 - - 0.0 1047.0
CMS1_k127_45678_2 pyrroloquinoline quinone binding - - - 3.628e-239 751.0
CMS1_k127_45678_3 DUF1704 - - - 2.859e-194 614.0
CMS1_k127_45678_4 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 613.0
CMS1_k127_45678_5 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007782 363.0
CMS1_k127_45678_6 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 324.0
CMS1_k127_45678_7 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000001189 154.0
CMS1_k127_45678_9 metal-dependent phosphohydrolase HD sub domain - - - 0.00000000006922 68.0
CMS1_k127_4574607_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0 1185.0
CMS1_k127_4574607_1 Protein of unknown function (DUF1566) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 411.0
CMS1_k127_4574607_10 ABC-type phosphate transport system, periplasmic component - - - 0.000000000000000002654 89.0
CMS1_k127_4574607_11 repeat protein - - - 0.000000000001742 81.0
CMS1_k127_4574607_13 belongs to the thioredoxin family K03671 - - 0.000003462 50.0
CMS1_k127_4574607_2 Histidine kinase K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 397.0
CMS1_k127_4574607_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 290.0
CMS1_k127_4574607_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004877 263.0
CMS1_k127_4574607_5 self proteolysis K01406 - 3.4.24.40 0.000000000000000000000000000000000000000000000000000000000000000000000002409 268.0
CMS1_k127_4574607_6 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000001066 182.0
CMS1_k127_4574607_8 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.0000000000000000000004599 96.0
CMS1_k127_4574607_9 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000001184 101.0
CMS1_k127_4589533_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0 1899.0
CMS1_k127_4589533_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1122.0
CMS1_k127_4589533_10 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 439.0
CMS1_k127_4589533_11 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 437.0
CMS1_k127_4589533_12 cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 348.0
CMS1_k127_4589533_13 Serine hydrolase K07002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 297.0
CMS1_k127_4589533_14 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 297.0
CMS1_k127_4589533_15 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 285.0
CMS1_k127_4589533_16 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001613 265.0
CMS1_k127_4589533_17 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000152 263.0
CMS1_k127_4589533_18 Phosphoesterase K07095 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001083 245.0
CMS1_k127_4589533_19 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.0000000000000000000000000000000000000000000000000000000000003767 224.0
CMS1_k127_4589533_2 Protein of unknown function (DUF1538) - - - 3.687e-297 922.0
CMS1_k127_4589533_20 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000001026 215.0
CMS1_k127_4589533_22 Protein-disulfide isomerase K07396 - - 0.0000000000000000000000000000000000000000652 158.0
CMS1_k127_4589533_23 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000007608 138.0
CMS1_k127_4589533_24 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 0.0000000000000000000000000000002664 132.0
CMS1_k127_4589533_28 - - - - 0.000000000000000556 81.0
CMS1_k127_4589533_29 AMIN domain - - - 0.00000000006131 71.0
CMS1_k127_4589533_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 7.622e-246 762.0
CMS1_k127_4589533_30 LPP20 lipoprotein - - - 0.0000003099 63.0
CMS1_k127_4589533_31 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000005245 57.0
CMS1_k127_4589533_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 599.0
CMS1_k127_4589533_5 Fad-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 597.0
CMS1_k127_4589533_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 513.0
CMS1_k127_4589533_7 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 493.0
CMS1_k127_4589533_8 pyridine nucleotide-disulfide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009931 487.0
CMS1_k127_4589533_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 485.0
CMS1_k127_4608411_0 Glycolate oxidase subunit K00104 - 1.1.3.15 3.556e-259 803.0
CMS1_k127_4608411_1 TonB-dependent copper receptor K02014 - - 8.681e-231 733.0
CMS1_k127_4608411_10 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000003489 223.0
CMS1_k127_4608411_11 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000003358 164.0
CMS1_k127_4608411_12 NlpC/P60 family K13695 - - 0.00000000000000000000000000000000000003004 148.0
CMS1_k127_4608411_13 - - - - 0.0000000000000000000000000000000000003242 143.0
CMS1_k127_4608411_14 Prokaryotic metallothionein K06950 - - 0.000000000002569 69.0
CMS1_k127_4608411_2 Belongs to the agmatine deiminase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 473.0
CMS1_k127_4608411_3 peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009998 423.0
CMS1_k127_4608411_4 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 411.0
CMS1_k127_4608411_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 372.0
CMS1_k127_4608411_6 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007996 297.0
CMS1_k127_4608411_7 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000248 277.0
CMS1_k127_4608411_8 Plasminogen-binding protein pgbA N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000001389 242.0
CMS1_k127_4608411_9 Nudix domain K08077 - 3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000001307 229.0
CMS1_k127_4624532_0 cytochrome c - - - 0.0 1249.0
CMS1_k127_4624532_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 8.269e-241 754.0
CMS1_k127_4624532_10 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000003369 216.0
CMS1_k127_4624532_11 - - - - 0.00000000000000000000000000000000000000000000000000000000007413 207.0
CMS1_k127_4624532_12 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000001498 128.0
CMS1_k127_4624532_13 Preprotein translocase, YajC subunit K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000005558 106.0
CMS1_k127_4624532_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 607.0
CMS1_k127_4624532_3 Peptidase, M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 505.0
CMS1_k127_4624532_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 481.0
CMS1_k127_4624532_5 apolipoprotein N-acyltransferase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 440.0
CMS1_k127_4624532_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 377.0
CMS1_k127_4624532_7 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005977 274.0
CMS1_k127_4624532_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000001404 250.0
CMS1_k127_4624532_9 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000000000006399 232.0
CMS1_k127_4659654_0 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 0.0 1588.0
CMS1_k127_4659654_1 Cytochrome c biogenesis protein - - - 0.0 1283.0
CMS1_k127_4659654_10 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 2.361e-280 864.0
CMS1_k127_4659654_11 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 4.267e-245 761.0
CMS1_k127_4659654_12 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 6.597e-221 688.0
CMS1_k127_4659654_13 Oxidoreductase K00174 - 1.2.7.11,1.2.7.3 2.05e-210 657.0
CMS1_k127_4659654_14 Aminotransferase K00812 - 2.6.1.1 9.629e-201 630.0
CMS1_k127_4659654_15 histidyl-tRNA synthetase K01892 - 6.1.1.21 2.369e-195 615.0
CMS1_k127_4659654_16 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 591.0
CMS1_k127_4659654_17 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006346 585.0
CMS1_k127_4659654_18 Heterodisulfide reductase subunit B K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 577.0
CMS1_k127_4659654_19 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 580.0
CMS1_k127_4659654_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1266.0
CMS1_k127_4659654_20 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 568.0
CMS1_k127_4659654_21 epimerase dehydratase family K01784,K08679 - 5.1.3.2,5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 546.0
CMS1_k127_4659654_22 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 527.0
CMS1_k127_4659654_23 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 526.0
CMS1_k127_4659654_24 Oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 516.0
CMS1_k127_4659654_25 AsmA-like C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 516.0
CMS1_k127_4659654_26 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 481.0
CMS1_k127_4659654_27 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 481.0
CMS1_k127_4659654_28 PFAM SufBD protein K07033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 415.0
CMS1_k127_4659654_29 hmm pf00534 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 409.0
CMS1_k127_4659654_3 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1251.0
CMS1_k127_4659654_30 ABC transporter, ATP-binding protein K01990,K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 398.0
CMS1_k127_4659654_31 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 400.0
CMS1_k127_4659654_32 serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 378.0
CMS1_k127_4659654_33 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 382.0
CMS1_k127_4659654_34 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 370.0
CMS1_k127_4659654_35 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 355.0
CMS1_k127_4659654_36 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 353.0
CMS1_k127_4659654_38 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 341.0
CMS1_k127_4659654_39 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 337.0
CMS1_k127_4659654_4 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1244.0
CMS1_k127_4659654_40 PFAM amine oxidase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 335.0
CMS1_k127_4659654_41 oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 321.0
CMS1_k127_4659654_42 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 322.0
CMS1_k127_4659654_43 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 302.0
CMS1_k127_4659654_44 coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 306.0
CMS1_k127_4659654_45 tigr02757 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 290.0
CMS1_k127_4659654_46 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 284.0
CMS1_k127_4659654_47 Histidine kinase A domain protein K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002428 308.0
CMS1_k127_4659654_49 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004236 282.0
CMS1_k127_4659654_5 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 1.181e-320 987.0
CMS1_k127_4659654_50 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000017 271.0
CMS1_k127_4659654_51 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000474 264.0
CMS1_k127_4659654_52 MafB19-like deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000457 254.0
CMS1_k127_4659654_53 Polysaccharide biosynthesis protein K03328 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004253 266.0
CMS1_k127_4659654_54 General glycosylation pathway protein K17249 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.292 0.0000000000000000000000000000000000000000000000000000000000000000000000001109 261.0
CMS1_k127_4659654_55 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000158 247.0
CMS1_k127_4659654_56 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005329 261.0
CMS1_k127_4659654_57 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000001495 238.0
CMS1_k127_4659654_58 Prolyl 4-hydroxylase alpha subunit homologues. K07394 - - 0.0000000000000000000000000000000000000000000000000000000000000000009871 235.0
CMS1_k127_4659654_59 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000001439 231.0
CMS1_k127_4659654_6 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 7.736e-316 977.0
CMS1_k127_4659654_60 acetolactate synthase K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000006649 228.0
CMS1_k127_4659654_61 glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000005167 237.0
CMS1_k127_4659654_62 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000000000006006 222.0
CMS1_k127_4659654_63 phosphoribosyltransferase K00769 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000002928 220.0
CMS1_k127_4659654_64 2-oxoglutarate acceptor oxidoreductase K00176 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000009282 210.0
CMS1_k127_4659654_65 Phospholipid methyltransferase K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000000000000000000006366 215.0
CMS1_k127_4659654_66 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000001102 208.0
CMS1_k127_4659654_67 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000004712 214.0
CMS1_k127_4659654_68 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000003832 212.0
CMS1_k127_4659654_69 - - - - 0.00000000000000000000000000000000000000000000000000001591 194.0
CMS1_k127_4659654_7 acetolactate synthase K01652 - 2.2.1.6 1.935e-315 973.0
CMS1_k127_4659654_70 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000000000000000167 189.0
CMS1_k127_4659654_71 PFAM O-Antigen - - - 0.00000000000000000000000000000000000000000000000003687 194.0
CMS1_k127_4659654_72 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.00000000000000000000000000000000000000000000000008549 191.0
CMS1_k127_4659654_73 Staphylococcal nuclease homologue - - - 0.0000000000000000000000000000000000000000000001005 173.0
CMS1_k127_4659654_74 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000003728 171.0
CMS1_k127_4659654_75 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.00000000000000000000000000000000000000005045 172.0
CMS1_k127_4659654_76 ATPase or kinase K06925 - - 0.00000000000000000000000000000000000001443 149.0
CMS1_k127_4659654_77 Cytochrome P460 - - - 0.00000000000000000000000000000000000001814 149.0
CMS1_k127_4659654_78 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000003175 144.0
CMS1_k127_4659654_79 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000006185 143.0
CMS1_k127_4659654_8 arginine decarboxylase K01585 - 4.1.1.19 2.454e-295 915.0
CMS1_k127_4659654_80 Heavy-metal-associated domain - - - 0.000000000000000000000000000000000009825 138.0
CMS1_k127_4659654_81 - - - - 0.0000000000000000000000000000000001437 135.0
CMS1_k127_4659654_82 S4 domain protein - - - 0.000000000000000000000000000009929 119.0
CMS1_k127_4659654_83 - - - - 0.000000000000000000000000007894 110.0
CMS1_k127_4659654_84 Protein conserved in bacteria - - - 0.0000000000000000000006399 113.0
CMS1_k127_4659654_85 Glycosyltransferase, group 1 family protein - - - 0.0000000000000001862 91.0
CMS1_k127_4659654_87 BPTI/Kunitz family of serine protease inhibitors. - - - 0.0000004134 59.0
CMS1_k127_4659654_88 - - - - 0.0000006808 53.0
CMS1_k127_4659654_89 Belongs to the 'phage' integrase family K03111 - - 0.0002356 43.0
CMS1_k127_4659654_9 Belongs to the FtsK SpoIIIE SftA family K03466 - - 4.312e-289 906.0
CMS1_k127_4659654_90 - - - - 0.0007838 48.0
CMS1_k127_4690776_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1470.0
CMS1_k127_4690776_1 DNA helicase K03657 - 3.6.4.12 0.0 1045.0
CMS1_k127_4690776_2 COG0659 Sulfate permease and related K03321 - - 2.186e-242 760.0
CMS1_k127_4690776_3 Type II secretion system K02455,K12278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 362.0
CMS1_k127_4690776_4 GatB Yqey family protein K09117 - - 0.000000000000000000000000000000000000000000000000000001436 194.0
CMS1_k127_4690776_5 - - - - 0.00000000000000009465 81.0
CMS1_k127_4690776_6 Domain of unknown function (DUF4386) - - - 0.000001536 51.0
CMS1_k127_4712210_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1283.0
CMS1_k127_4712210_1 Abc transporter K06158 - - 4.711e-283 881.0
CMS1_k127_4712210_10 Domain of unknown function (DUF386) - - - 0.0000000000000000000000000000000000000000000000000000000000000601 216.0
CMS1_k127_4712210_11 Belongs to the UPF0763 family - - - 0.000000000000000000000000000000000000000000000000000000000009347 211.0
CMS1_k127_4712210_12 Pentapeptide repeat - - - 0.000000000000000000000000000000000000000000000000000008644 196.0
CMS1_k127_4712210_13 Cupin domain - - - 0.0000000000000000000000000000000000000000000000004479 180.0
CMS1_k127_4712210_14 COG0760 Parvulin-like peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000006253 152.0
CMS1_k127_4712210_15 - - - - 0.0000000000000000000000000000000000000002657 151.0
CMS1_k127_4712210_16 fatty acid desaturase - - - 0.0000000000000000000000000000007215 134.0
CMS1_k127_4712210_17 phosphate-selective porin O and P - - - 0.00000000000000000000000000002446 118.0
CMS1_k127_4712210_18 Transcriptional regulator - - - 0.0000000000000000000000001508 111.0
CMS1_k127_4712210_19 - - - - 0.0000000000000002168 81.0
CMS1_k127_4712210_2 Ribonuclease K12573 - - 1.856e-260 819.0
CMS1_k127_4712210_20 Sel1-like repeats. K07126 - - 0.000000001448 70.0
CMS1_k127_4712210_3 COG0803 ABC-type metal ion transport system, periplasmic component surface adhesin K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 432.0
CMS1_k127_4712210_4 DNA polymerase III K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 361.0
CMS1_k127_4712210_5 Pseudouridine synthase K06175 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 317.0
CMS1_k127_4712210_6 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 301.0
CMS1_k127_4712210_7 radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0042221,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 297.0
CMS1_k127_4712210_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002687 255.0
CMS1_k127_4712210_9 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000002946 228.0
CMS1_k127_4731700_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1545.0
CMS1_k127_4731700_1 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 526.0
CMS1_k127_4731700_10 Protein of unknown function (DUF819) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 324.0
CMS1_k127_4731700_11 long-chain fatty acid transporting porin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 300.0
CMS1_k127_4731700_12 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 299.0
CMS1_k127_4731700_13 COG2346 Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001732 249.0
CMS1_k127_4731700_14 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000003173 220.0
CMS1_k127_4731700_15 Protein of unknown function, DUF255 - - - 0.00000000000000000000000000000000000000000005649 165.0
CMS1_k127_4731700_16 response regulator - - - 0.0000000000000000000000000000000000000006073 156.0
CMS1_k127_4731700_17 YtkA-like - - - 0.00000000000000000000000000000006337 128.0
CMS1_k127_4731700_18 beta-lactamase activity K07126,K15474 - - 0.000000000000000000001319 98.0
CMS1_k127_4731700_19 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000174 84.0
CMS1_k127_4731700_2 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 486.0
CMS1_k127_4731700_20 endonuclease containing a URI domain K07461 - - 0.000000000000000004433 98.0
CMS1_k127_4731700_21 Cytochrome c - - - 0.00000000000000003882 83.0
CMS1_k127_4731700_22 Belongs to the UPF0312 family - - - 0.0000000000000008895 83.0
CMS1_k127_4731700_23 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000003847 73.0
CMS1_k127_4731700_3 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 425.0
CMS1_k127_4731700_4 COG1538 Outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008759 391.0
CMS1_k127_4731700_5 COGs COG3864 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 373.0
CMS1_k127_4731700_6 YHS domain K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 355.0
CMS1_k127_4731700_7 lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 359.0
CMS1_k127_4731700_8 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 346.0
CMS1_k127_4731700_9 cation efflux system protein K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 349.0
CMS1_k127_4742902_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K16881 - 2.7.7.13,5.4.2.8 0.0 1372.0
CMS1_k127_4742902_1 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1172.0
CMS1_k127_4742902_10 Small subunit K05927 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.5.1 9.912e-230 715.0
CMS1_k127_4742902_11 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.527e-201 637.0
CMS1_k127_4742902_12 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 6.735e-201 631.0
CMS1_k127_4742902_13 Methyltransferase type 11 K07755 - 2.1.1.137 1.557e-195 619.0
CMS1_k127_4742902_14 Belongs to the HypD family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 604.0
CMS1_k127_4742902_15 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 513.0
CMS1_k127_4742902_16 hydrogenase expression formation protein K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 497.0
CMS1_k127_4742902_17 Hydrogenase K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003487 441.0
CMS1_k127_4742902_18 NADPH quinone reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 379.0
CMS1_k127_4742902_19 COGs COG1940 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 368.0
CMS1_k127_4742902_2 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0 1072.0
CMS1_k127_4742902_20 Ni Fe-hydrogenase, b-type cytochrome subunit K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 349.0
CMS1_k127_4742902_21 hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 305.0
CMS1_k127_4742902_22 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002153 279.0
CMS1_k127_4742902_23 PFAM Galactose-1-phosphate uridyl transferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000001066 199.0
CMS1_k127_4742902_24 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide - - - 0.0000000000000000000000000000000000000000000000154 192.0
CMS1_k127_4742902_25 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000000000000000000000448 164.0
CMS1_k127_4742902_26 - - - - 0.0000000000000000000000000000000000000007295 149.0
CMS1_k127_4742902_27 hydrogenase assembly chaperone HypC K04653 - - 0.00000000000000000000000000000000000001452 145.0
CMS1_k127_4742902_3 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1055.0
CMS1_k127_4742902_4 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.5.1 0.0 1017.0
CMS1_k127_4742902_5 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 6.715e-315 980.0
CMS1_k127_4742902_6 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 8e-310 953.0
CMS1_k127_4742902_7 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 2.63e-306 944.0
CMS1_k127_4742902_8 hydrogenase (NiFe) small subunit HydA K05927 - 1.12.5.1 1.552e-282 878.0
CMS1_k127_4742902_9 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.169e-273 847.0
CMS1_k127_4789330_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 9.201e-206 647.0
CMS1_k127_4789330_1 Nitrogen fixation protein NifW K02595 - - 0.00000000000000000000000000000000000000000000000000000002691 201.0
CMS1_k127_4789330_2 Low-potential electron donor to a number of redox enzymes K03839 - - 0.000000000000000000000000000000000000000000000000007818 181.0
CMS1_k127_4789330_3 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000001681 177.0
CMS1_k127_4789330_4 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000004562 178.0
CMS1_k127_4789330_5 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000002592 150.0
CMS1_k127_4789330_6 NifZ domain K02597 - - 0.00000000000000000007387 94.0
CMS1_k127_4912275_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.124e-247 765.0
CMS1_k127_4912275_1 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 590.0
CMS1_k127_4912275_10 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 336.0
CMS1_k127_4912275_11 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 324.0
CMS1_k127_4912275_12 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 294.0
CMS1_k127_4912275_13 Fibronectin type 3 domain-containing protein K06882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006237 285.0
CMS1_k127_4912275_14 na -driven multidrug efflux - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005602 254.0
CMS1_k127_4912275_15 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.00000000000000000000000000000000000000000000000000000000001257 211.0
CMS1_k127_4912275_16 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000001014 204.0
CMS1_k127_4912275_18 Cell division protein FtsX K09811 - - 0.000000000000000000000000000000000005253 148.0
CMS1_k127_4912275_19 na -driven multidrug efflux - - - 0.000000000000000000000000000000000006979 151.0
CMS1_k127_4912275_2 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 550.0
CMS1_k127_4912275_20 - - - - 0.00000000000000000000000001963 110.0
CMS1_k127_4912275_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 484.0
CMS1_k127_4912275_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 477.0
CMS1_k127_4912275_5 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 455.0
CMS1_k127_4912275_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 429.0
CMS1_k127_4912275_7 Epimerase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 419.0
CMS1_k127_4912275_8 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 377.0
CMS1_k127_4912275_9 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 344.0
CMS1_k127_4912821_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1266.0
CMS1_k127_4912821_1 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 2.731e-211 672.0
CMS1_k127_4912821_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 563.0
CMS1_k127_4912821_3 Protein of unknown function (DUF475) K09799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 521.0
CMS1_k127_4912821_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 368.0
CMS1_k127_4912821_5 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 343.0
CMS1_k127_4912821_6 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 320.0
CMS1_k127_4912821_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 284.0
CMS1_k127_4912821_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000001394 191.0
CMS1_k127_4912821_9 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000005214 96.0
CMS1_k127_501561_0 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 601.0
CMS1_k127_501561_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 542.0
CMS1_k127_501561_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 480.0
CMS1_k127_501561_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 474.0
CMS1_k127_501561_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 409.0
CMS1_k127_501561_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002073 254.0
CMS1_k127_501561_6 Protein of unknown function, DUF255 - - - 0.00000000000000000000000000002926 121.0
CMS1_k127_5134562_0 COGs COG1033 exporter of the RND superfamily protein K07003 - - 1.058e-306 957.0
CMS1_k127_5134562_1 Heat shock 70 kDa protein K04043 - - 1.307e-266 833.0
CMS1_k127_5134562_10 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 352.0
CMS1_k127_5134562_11 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 345.0
CMS1_k127_5134562_12 alpha beta K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 317.0
CMS1_k127_5134562_13 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 312.0
CMS1_k127_5134562_14 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 307.0
CMS1_k127_5134562_15 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 291.0
CMS1_k127_5134562_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005407 284.0
CMS1_k127_5134562_17 PhnA Zinc-Ribbon K06193 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001648 275.0
CMS1_k127_5134562_18 Copper resistance protein B precursor (CopB) K07233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001301 252.0
CMS1_k127_5134562_19 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001743 248.0
CMS1_k127_5134562_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 5.267e-263 819.0
CMS1_k127_5134562_20 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008314 242.0
CMS1_k127_5134562_21 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000008799 232.0
CMS1_k127_5134562_22 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000004434 231.0
CMS1_k127_5134562_23 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000007375 215.0
CMS1_k127_5134562_24 - - - - 0.000000000000000000000000000000000000000000000000000000000001846 212.0
CMS1_k127_5134562_25 chain release factor K15034 - - 0.00000000000000000000000000000000000000000000000000000000001152 209.0
CMS1_k127_5134562_26 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000004947 213.0
CMS1_k127_5134562_27 WHG domain - - - 0.0000000000000000000000000000000000000000000000000000006901 199.0
CMS1_k127_5134562_28 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000119 191.0
CMS1_k127_5134562_29 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000001418 183.0
CMS1_k127_5134562_3 Multicopper oxidase K22348 - 1.16.3.3 5.327e-247 774.0
CMS1_k127_5134562_30 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000000000005112 177.0
CMS1_k127_5134562_31 COG1734 DnaK suppressor protein K06204 - - 0.0000000000000000000000000000000000002953 144.0
CMS1_k127_5134562_32 PFAM Pyridine nucleotide-disulphide oxidoreductase, FAD NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000003214 119.0
CMS1_k127_5134562_33 - - - - 0.000000000000000000000000001689 113.0
CMS1_k127_5134562_34 secretion protein HlyD K01993 - - 0.00000000000000000000000000999 115.0
CMS1_k127_5134562_35 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000004151 94.0
CMS1_k127_5134562_36 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000005147 81.0
CMS1_k127_5134562_37 membrane protein (homolog of Drosophila rhomboid) - - - 0.00000000000005792 80.0
CMS1_k127_5134562_38 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000001305 70.0
CMS1_k127_5134562_39 ABC-type multidrug transport system, permease component K01992 - - 0.000000000001562 70.0
CMS1_k127_5134562_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.516e-226 706.0
CMS1_k127_5134562_42 - - - - 0.000003222 49.0
CMS1_k127_5134562_43 alanine dehydrogenase K00259 - 1.4.1.1 0.00001884 48.0
CMS1_k127_5134562_5 PFAM Radical SAM domain protein K04069 - 1.97.1.4 5.136e-210 655.0
CMS1_k127_5134562_6 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 430.0
CMS1_k127_5134562_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 422.0
CMS1_k127_5134562_8 Metal cation transporter, ZIP family K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 398.0
CMS1_k127_5134562_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 366.0
CMS1_k127_517131_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 1.242e-242 757.0
CMS1_k127_517131_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.797e-196 616.0
CMS1_k127_517131_2 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000003744 102.0
CMS1_k127_517131_3 Competence protein K02238 - - 0.000000000002318 72.0
CMS1_k127_538343_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 6.14e-252 787.0
CMS1_k127_538343_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 586.0
CMS1_k127_538343_10 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000005729 126.0
CMS1_k127_538343_11 - - - - 0.0000000000000000000000000002355 117.0
CMS1_k127_538343_12 DNA-binding protein VF530 - - - 0.000000000000000000000000005531 112.0
CMS1_k127_538343_2 Membrane protease subunits - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 400.0
CMS1_k127_538343_3 conserved protein UCP016719 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 373.0
CMS1_k127_538343_4 diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 353.0
CMS1_k127_538343_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 334.0
CMS1_k127_538343_6 Pseudouridine synthase K06177,K06179,K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 312.0
CMS1_k127_538343_8 Histidine kinase - - - 0.000000000000000000000000000000000000004667 152.0
CMS1_k127_538343_9 Membrane protein implicated in regulation of membrane protease activity K07340 - - 0.000000000000000000000000000000000000131 146.0
CMS1_k127_5401173_0 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains K02584 - - 1.205e-263 820.0
CMS1_k127_5401173_1 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 2.396e-232 731.0
CMS1_k127_5401173_2 AhpC/TSA family K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000002317 266.0
CMS1_k127_5401173_3 TIGRFAM SagB-type dehydrogenase domain - - - 0.0000000000000000000000000000000000000000000000000000000005578 207.0
CMS1_k127_5401173_4 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000001069 200.0
CMS1_k127_5401173_5 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000006505 172.0
CMS1_k127_5401173_6 nitrogen fixation protein FixT K02593 - - 0.00000000000000000000839 93.0
CMS1_k127_5488331_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 2054.0
CMS1_k127_5488331_1 Belongs to the ClpA ClpB family K03694,K03695 - - 0.0 1373.0
CMS1_k127_5488331_10 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.426e-203 643.0
CMS1_k127_5488331_11 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 3.484e-199 637.0
CMS1_k127_5488331_12 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 602.0
CMS1_k127_5488331_13 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 590.0
CMS1_k127_5488331_14 fructose-bisphosphate aldolase K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 582.0
CMS1_k127_5488331_15 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 556.0
CMS1_k127_5488331_16 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 536.0
CMS1_k127_5488331_17 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 505.0
CMS1_k127_5488331_18 dihydropteroate synthase K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 483.0
CMS1_k127_5488331_19 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 487.0
CMS1_k127_5488331_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1052.0
CMS1_k127_5488331_20 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 467.0
CMS1_k127_5488331_21 4Fe-4S ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 437.0
CMS1_k127_5488331_22 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 432.0
CMS1_k127_5488331_23 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 437.0
CMS1_k127_5488331_24 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 411.0
CMS1_k127_5488331_25 PFAM 5'-nucleotidase K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 406.0
CMS1_k127_5488331_26 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 364.0
CMS1_k127_5488331_27 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 350.0
CMS1_k127_5488331_28 COG1252 NADH dehydrogenase FAD-containing subunit K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 352.0
CMS1_k127_5488331_29 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 340.0
CMS1_k127_5488331_3 Heat shock 70 kDa protein K04043 - - 0.0 1013.0
CMS1_k127_5488331_30 Dipeptidase K01270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 344.0
CMS1_k127_5488331_31 Jag_N K06346 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 334.0
CMS1_k127_5488331_32 peptidylprolyl isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 324.0
CMS1_k127_5488331_33 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 317.0
CMS1_k127_5488331_34 1-aminocyclopropane-1-carboxylate deaminase K01505 - 3.5.99.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 307.0
CMS1_k127_5488331_35 ABC transporter, ATP-binding protein K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002451 265.0
CMS1_k127_5488331_36 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000001625 266.0
CMS1_k127_5488331_37 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000024 259.0
CMS1_k127_5488331_38 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000003138 260.0
CMS1_k127_5488331_39 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009936 262.0
CMS1_k127_5488331_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 5.044e-239 743.0
CMS1_k127_5488331_40 DNA processing protein K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001866 253.0
CMS1_k127_5488331_41 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001878 241.0
CMS1_k127_5488331_42 DNA replication regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000004965 238.0
CMS1_k127_5488331_43 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000000000002008 236.0
CMS1_k127_5488331_44 PFAM Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000005869 231.0
CMS1_k127_5488331_45 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000002933 223.0
CMS1_k127_5488331_46 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K01823,K06989 - 1.4.1.21,5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000005826 227.0
CMS1_k127_5488331_47 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000001244 222.0
CMS1_k127_5488331_48 transformation system protein K02242 - - 0.000000000000000000000000000000000000000000000000000000000000002113 222.0
CMS1_k127_5488331_49 component of anaerobic - - - 0.00000000000000000000000000000000000000000000000000000000000007054 219.0
CMS1_k127_5488331_5 COG0642 Signal transduction histidine kinase - - - 3.507e-224 712.0
CMS1_k127_5488331_50 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000005845 199.0
CMS1_k127_5488331_51 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000007956 195.0
CMS1_k127_5488331_52 - - - - 0.00000000000000000000000000000000000000000000000000003246 195.0
CMS1_k127_5488331_53 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000000000000004369 190.0
CMS1_k127_5488331_54 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000456 190.0
CMS1_k127_5488331_55 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000005776 189.0
CMS1_k127_5488331_56 Membrane - - - 0.000000000000000000000000000000000000000000000000007922 188.0
CMS1_k127_5488331_57 Highly conserved protein containing a thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000002218 183.0
CMS1_k127_5488331_58 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000000000000000002773 179.0
CMS1_k127_5488331_59 Belongs to the bacterial histone-like protein family K03530 - - 0.0000000000000000000000000000000000000000000147 163.0
CMS1_k127_5488331_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 5.243e-213 673.0
CMS1_k127_5488331_60 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.0000000000000000000000000000000000000000000273 164.0
CMS1_k127_5488331_61 protein conserved in bacteria K09928 - - 0.000000000000000000000000000000000000003811 152.0
CMS1_k127_5488331_62 Could be involved in insertion of integral membrane proteins into the membrane - - - 0.000000000000000000000000000000000000004576 147.0
CMS1_k127_5488331_63 - - - - 0.0000000000000000000000000000000000000873 145.0
CMS1_k127_5488331_64 Protein required for attachment to host cells - - - 0.000000000000000000000000000000000001925 143.0
CMS1_k127_5488331_65 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000001832 136.0
CMS1_k127_5488331_67 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000002584 123.0
CMS1_k127_5488331_68 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000009128 119.0
CMS1_k127_5488331_69 - - - - 0.000000000000000000001352 98.0
CMS1_k127_5488331_7 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.027e-212 665.0
CMS1_k127_5488331_70 Cupin domain K11312 - - 0.00000000000000000000149 100.0
CMS1_k127_5488331_71 OmpA-like transmembrane domain - - - 0.000000000000000000008451 100.0
CMS1_k127_5488331_72 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000000006715 80.0
CMS1_k127_5488331_8 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 1.373e-209 657.0
CMS1_k127_5488331_9 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 3.006e-209 653.0
CMS1_k127_5516487_0 Amidohydrolase family - - - 1.823e-210 667.0
CMS1_k127_5516487_1 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 359.0
CMS1_k127_5516487_10 integral membrane protein - - - 0.0001627 51.0
CMS1_k127_5516487_11 Belongs to the sulfur carrier protein TusA family K08363 - - 0.0002876 48.0
CMS1_k127_5516487_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 331.0
CMS1_k127_5516487_3 Alkyl hydroperoxide reductase K03387 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 308.0
CMS1_k127_5516487_4 hmm pf01841 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008502 292.0
CMS1_k127_5516487_5 Bacterial protein of unknown function (DUF898) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 295.0
CMS1_k127_5516487_6 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000005387 97.0
CMS1_k127_5516487_7 Trypsin-like serine protease - - - 0.000000000000000000002491 109.0
CMS1_k127_5516487_8 Heavy-metal-associated domain K08364 - - 0.00000000000000003757 87.0
CMS1_k127_555258_0 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 5.259e-210 661.0
CMS1_k127_555258_1 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 497.0
CMS1_k127_555258_10 Bacterial Ig-like domain 2 - - - 0.000007242 57.0
CMS1_k127_555258_11 Belongs to the ompA family K03286 - - 0.00004373 53.0
CMS1_k127_555258_2 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 450.0
CMS1_k127_555258_3 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 408.0
CMS1_k127_555258_4 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 301.0
CMS1_k127_555258_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000001337 230.0
CMS1_k127_555258_6 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000001903 231.0
CMS1_k127_555258_7 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000005588 208.0
CMS1_k127_555258_8 Nitrogen fixation protein NifU - - - 0.000000000000000000000000000000000000000000004389 164.0
CMS1_k127_555258_9 - - - - 0.00000000000000000000000000000000000004065 150.0
CMS1_k127_5584_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 580.0
CMS1_k127_5584_1 COG0155 Sulfite reductase, beta subunit (hemoprotein) K00366,K00392 - 1.7.7.1,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 548.0
CMS1_k127_5584_10 homoserine kinase type II (Protein kinase fold) K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000009682 187.0
CMS1_k127_5584_11 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000002286 183.0
CMS1_k127_5584_12 PFAM Cobinamide kinase cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000001044 89.0
CMS1_k127_5584_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 338.0
CMS1_k127_5584_3 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 317.0
CMS1_k127_5584_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 314.0
CMS1_k127_5584_5 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001202 286.0
CMS1_k127_5584_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000001682 214.0
CMS1_k127_5584_7 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000002297 214.0
CMS1_k127_5584_8 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000001092 199.0
CMS1_k127_5584_9 COGs COG1120 ABC-type cobalamin Fe3 -siderophores transport systems ATPase components K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000001024 202.0
CMS1_k127_5604533_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 3.712e-291 907.0
CMS1_k127_5604533_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.802e-224 703.0
CMS1_k127_5604533_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 389.0
CMS1_k127_5604533_11 Glycosyl hydrolase family 3 K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 347.0
CMS1_k127_5604533_12 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 332.0
CMS1_k127_5604533_13 Curli production assembly/transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 336.0
CMS1_k127_5604533_14 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 330.0
CMS1_k127_5604533_15 leucine binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 327.0
CMS1_k127_5604533_16 NUDIX domain K16855 - 3.6.1.62,3.6.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 304.0
CMS1_k127_5604533_17 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 306.0
CMS1_k127_5604533_18 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007451 286.0
CMS1_k127_5604533_19 HIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007803 269.0
CMS1_k127_5604533_2 Mur ligase middle domain K01929 - 6.3.2.10 1.974e-200 634.0
CMS1_k127_5604533_20 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000007481 264.0
CMS1_k127_5604533_21 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005593 256.0
CMS1_k127_5604533_22 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000006195 250.0
CMS1_k127_5604533_23 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000006856 254.0
CMS1_k127_5604533_24 COG4464 Capsular polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008641 256.0
CMS1_k127_5604533_25 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000000001947 219.0
CMS1_k127_5604533_26 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000000000000000000000006572 202.0
CMS1_k127_5604533_27 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.00000000000000000000000000000000000000000000000003405 183.0
CMS1_k127_5604533_28 thioesterase K07107 - - 0.000000000000000000000000000000000000000000152 162.0
CMS1_k127_5604533_29 alpha beta K06889 - - 0.000000000000000000000000000000000000000002098 168.0
CMS1_k127_5604533_3 TRAP transporter, DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 605.0
CMS1_k127_5604533_30 Membrane K08988 - - 0.0000000000000000000000000000000000000001133 159.0
CMS1_k127_5604533_31 Thiamine-binding protein - - - 0.00000000000000000000000000000000000000204 149.0
CMS1_k127_5604533_32 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000004247 140.0
CMS1_k127_5604533_33 Belongs to the ompA family K03286 - - 0.000000000000000000000000000002317 133.0
CMS1_k127_5604533_34 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000003067 111.0
CMS1_k127_5604533_37 Protein of unknown function (DUF4242) - - - 0.0006972 44.0
CMS1_k127_5604533_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 582.0
CMS1_k127_5604533_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 509.0
CMS1_k127_5604533_6 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 497.0
CMS1_k127_5604533_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 481.0
CMS1_k127_5604533_8 COGs COG0665 Glycine D-amino acid oxidase (deaminating) K15461 - 2.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 417.0
CMS1_k127_5604533_9 leucine binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 402.0
CMS1_k127_5747950_0 protein involved in exopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 586.0
CMS1_k127_5747950_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 306.0
CMS1_k127_5747950_2 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000008105 235.0
CMS1_k127_5747950_3 signal transduction sensor histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000005628 215.0
CMS1_k127_5747950_4 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000000000000000000000009443 179.0
CMS1_k127_5801610_0 Allophanate hydrolase subunit 1 K01941 - 6.3.4.6 0.0 1538.0
CMS1_k127_5801610_1 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 1.078e-315 969.0
CMS1_k127_5801610_10 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 545.0
CMS1_k127_5801610_11 Glycosyltransferase like family 2 K21349 - 2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 514.0
CMS1_k127_5801610_12 COG4886 Leucine-rich repeat (LRR) protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 487.0
CMS1_k127_5801610_13 SIR2-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 467.0
CMS1_k127_5801610_14 alanine dehydrogenase K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006155 456.0
CMS1_k127_5801610_15 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009238 432.0
CMS1_k127_5801610_16 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 433.0
CMS1_k127_5801610_17 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 422.0
CMS1_k127_5801610_18 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 409.0
CMS1_k127_5801610_19 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 398.0
CMS1_k127_5801610_2 Nitrogenase protein alpha chain K02586 - 1.18.6.1 1.559e-301 927.0
CMS1_k127_5801610_20 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 364.0
CMS1_k127_5801610_21 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 365.0
CMS1_k127_5801610_22 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 365.0
CMS1_k127_5801610_23 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 332.0
CMS1_k127_5801610_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000001402 221.0
CMS1_k127_5801610_25 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000001525 184.0
CMS1_k127_5801610_26 PFAM Ferric reductase domain protein transmembrane component domain K17247 - - 0.00000000000000000000000000000000000000000000001173 177.0
CMS1_k127_5801610_27 translation initiation factor activity K06996 - - 0.0000000000000000000000000000000000000003573 161.0
CMS1_k127_5801610_28 - - - - 0.000000000000000000000000000000000000005288 149.0
CMS1_k127_5801610_3 Nitrogenase cofactor biosynthesis protein NifB K02585 - - 6.157e-280 863.0
CMS1_k127_5801610_30 Pathogenicity locus - - - 0.0000000000000000000000000000004045 124.0
CMS1_k127_5801610_31 - - - - 0.0000000000000000000000000000006773 123.0
CMS1_k127_5801610_33 Rop-like - - - 0.0000000000000000001234 91.0
CMS1_k127_5801610_34 homolog of gamma-carboxymuconolactone decarboxylase subunit - - - 0.00000000000000001548 86.0
CMS1_k127_5801610_36 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000005588 74.0
CMS1_k127_5801610_37 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.00000000003078 64.0
CMS1_k127_5801610_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.532e-222 694.0
CMS1_k127_5801610_5 Cysteine desulfurase K04487 - 2.8.1.7 6.822e-219 682.0
CMS1_k127_5801610_6 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 574.0
CMS1_k127_5801610_7 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 599.0
CMS1_k127_5801610_8 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 549.0
CMS1_k127_5801610_9 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 542.0
CMS1_k127_5935416_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1274.0
CMS1_k127_5935416_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 3.754e-258 814.0
CMS1_k127_5935416_10 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000001648 205.0
CMS1_k127_5935416_12 RESPONSE REGULATOR receiver K07288 - - 0.00000000000000002963 92.0
CMS1_k127_5935416_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 476.0
CMS1_k127_5935416_3 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 452.0
CMS1_k127_5935416_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 428.0
CMS1_k127_5935416_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 323.0
CMS1_k127_5935416_6 abc transporter atp-binding protein K02031,K15587 - 3.6.3.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 309.0
CMS1_k127_5935416_7 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 301.0
CMS1_k127_5935416_8 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 294.0
CMS1_k127_5935416_9 nucleotide-binding protein implicated in inhibition of septum formation K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008013 256.0
CMS1_k127_5969788_0 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1209.0
CMS1_k127_5969788_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 0.0 1182.0
CMS1_k127_5969788_10 Domain of unknown function (DUF4010) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 450.0
CMS1_k127_5969788_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 421.0
CMS1_k127_5969788_12 polyphosphate kinase K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 383.0
CMS1_k127_5969788_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 351.0
CMS1_k127_5969788_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 330.0
CMS1_k127_5969788_15 Long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 342.0
CMS1_k127_5969788_16 Wd-40 repeat - - - 0.000000000000000000000000000000000000000000000000000003455 211.0
CMS1_k127_5969788_17 - - - - 0.00000000000000000000000000000000000002767 149.0
CMS1_k127_5969788_18 putative NADH-ubiquinone oxidoreductase chain E K00334 - 1.6.5.3 0.0000000000000000000000000000000008783 130.0
CMS1_k127_5969788_19 Nucleotidyltransferase DNA polymerase involved in DNA repair K02346 - 2.7.7.7 0.0000000000000000001325 90.0
CMS1_k127_5969788_2 COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase K15022 - 1.17.1.10 0.0 1165.0
CMS1_k127_5969788_20 NADH dehydrogenase (ubiquinone) activity K00330 - 1.6.5.3 0.00000000000000304 80.0
CMS1_k127_5969788_3 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1040.0
CMS1_k127_5969788_4 ATPase (AAA - - - 9.205e-274 851.0
CMS1_k127_5969788_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.525e-255 789.0
CMS1_k127_5969788_6 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.776e-216 682.0
CMS1_k127_5969788_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 580.0
CMS1_k127_5969788_8 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 579.0
CMS1_k127_5969788_9 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 490.0
CMS1_k127_5977928_0 Aromatic amino acid lyase K01745 - 4.3.1.3 2.232e-199 632.0
CMS1_k127_5977928_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 566.0
CMS1_k127_5977928_10 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000001905 257.0
CMS1_k127_5977928_11 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000005415 249.0
CMS1_k127_5977928_12 Belongs to the beta-ketoacyl-ACP synthases family - - - 0.000000000000000000000000000000000000000000000000000000000000000001054 230.0
CMS1_k127_5977928_13 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000004882 227.0
CMS1_k127_5977928_14 beta-ketoacyl-acyl-carrier-protein synthase II activity - - - 0.00000000000000000000000000000000000000000000000000001733 201.0
CMS1_k127_5977928_15 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000001688 184.0
CMS1_k127_5977928_16 beta-lactamase - - - 0.000000000000000000000000000000000000002115 162.0
CMS1_k127_5977928_17 Lipid A biosynthesis acyltransferase - - - 0.00000000000000000000000000000000000008012 153.0
CMS1_k127_5977928_18 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 GO:0003674,GO:0003824,GO:0003841,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042171,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071617,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.51 0.0000000000000000000002372 107.0
CMS1_k127_5977928_19 Phosphopantetheine attachment site K02078 - - 0.000000000000000001922 89.0
CMS1_k127_5977928_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007542 524.0
CMS1_k127_5977928_20 - - - - 0.0000000000000005264 84.0
CMS1_k127_5977928_21 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000001882 79.0
CMS1_k127_5977928_22 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity K02372 - 4.2.1.59 0.00000000000005045 77.0
CMS1_k127_5977928_23 META domain - - - 0.0000000000009199 77.0
CMS1_k127_5977928_24 Phosphopantetheine attachment site K02078 - - 0.0000000005207 63.0
CMS1_k127_5977928_25 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000001715 53.0
CMS1_k127_5977928_26 - - - - 0.0000005271 61.0
CMS1_k127_5977928_27 - - - - 0.00006764 51.0
CMS1_k127_5977928_3 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 494.0
CMS1_k127_5977928_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 430.0
CMS1_k127_5977928_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 404.0
CMS1_k127_5977928_6 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 376.0
CMS1_k127_5977928_7 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 331.0
CMS1_k127_5977928_8 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 326.0
CMS1_k127_5977928_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 291.0
CMS1_k127_6238072_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 3.821e-314 981.0
CMS1_k127_6238072_1 Belongs to the UbiD family K03182 - 4.1.1.98 1.308e-299 928.0
CMS1_k127_6238072_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 331.0
CMS1_k127_6238072_11 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 312.0
CMS1_k127_6238072_12 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002765 249.0
CMS1_k127_6238072_13 Hit family K02503 - - 0.0000000000000000000000000000000000000000000000000000002075 195.0
CMS1_k127_6238072_14 - - - - 0.0000000000000000000000000000000000003691 142.0
CMS1_k127_6238072_2 ribosomal protein S1 K02945 - - 1.878e-276 858.0
CMS1_k127_6238072_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 4.054e-276 856.0
CMS1_k127_6238072_4 COG0841 Cation multidrug efflux pump - - - 2.856e-270 841.0
CMS1_k127_6238072_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 3.265e-263 818.0
CMS1_k127_6238072_6 argininosuccinate lyase K01755 - 4.3.2.1 1.169e-240 749.0
CMS1_k127_6238072_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 1.277e-203 642.0
CMS1_k127_6238072_8 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 575.0
CMS1_k127_6238072_9 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 426.0
CMS1_k127_6250277_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 393.0
CMS1_k127_6250277_1 involved in molybdopterin and thiamine biosynthesis family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 306.0
CMS1_k127_6250277_2 PFAM NHL repeat - - - 0.000000000000000000000000000000000000000007235 166.0
CMS1_k127_693842_0 ATP citrate synthase K15230 - 2.3.3.8 0.0 1124.0
CMS1_k127_693842_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1096.0
CMS1_k127_693842_10 general secretion pathway protein - - - 0.0000000000000000000000000000114 125.0
CMS1_k127_693842_11 general secretion pathway protein - - - 0.00000000000000000000000000003504 124.0
CMS1_k127_693842_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 9.981e-300 928.0
CMS1_k127_693842_3 Belongs to the succinate malate CoA ligase beta subunit family K15231 - 2.3.3.8 6.355e-249 772.0
CMS1_k127_693842_4 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 1.639e-196 616.0
CMS1_k127_693842_5 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 443.0
CMS1_k127_693842_6 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 439.0
CMS1_k127_693842_7 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 345.0
CMS1_k127_693842_8 Anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 320.0
CMS1_k127_693842_9 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000001534 196.0
CMS1_k127_70573_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1420.0
CMS1_k127_70573_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1298.0
CMS1_k127_70573_10 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000001055 208.0
CMS1_k127_70573_11 - - - - 0.000000000000000000000000000000000000000000000000001948 183.0
CMS1_k127_70573_12 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000000000000000004964 177.0
CMS1_k127_70573_13 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000478 112.0
CMS1_k127_70573_14 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000001673 88.0
CMS1_k127_70573_2 Belongs to the DEAD box helicase family - - - 3.365e-202 638.0
CMS1_k127_70573_3 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 512.0
CMS1_k127_70573_4 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 442.0
CMS1_k127_70573_5 metallophosphoesterase K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 400.0
CMS1_k127_70573_6 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 386.0
CMS1_k127_70573_7 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 328.0
CMS1_k127_70573_8 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008968 275.0
CMS1_k127_70573_9 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000006173 237.0
CMS1_k127_801643_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 5.206e-317 993.0
CMS1_k127_801643_1 COGs COG1252 NADH dehydrogenase FAD-containing subunit K17218 - 1.8.5.4 9.538e-293 901.0
CMS1_k127_801643_10 - - - - 0.000000000000000000000000000000000000000000000000001246 188.0
CMS1_k127_801643_11 PAP2 superfamily - - - 0.000000000000000000000000000000000000000000000003407 178.0
CMS1_k127_801643_12 domain, Protein - - - 0.00000000000000000000000000000000000000271 162.0
CMS1_k127_801643_13 - - - - 0.00000000000000000000000000000000001633 153.0
CMS1_k127_801643_14 - - - - 0.0000000000000000001872 88.0
CMS1_k127_801643_2 Hpt sensor hybrid histidine kinase - - - 5.183e-247 794.0
CMS1_k127_801643_3 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 508.0
CMS1_k127_801643_4 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 350.0
CMS1_k127_801643_5 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 317.0
CMS1_k127_801643_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 298.0
CMS1_k127_801643_7 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001424 278.0
CMS1_k127_801643_8 COG0242 N-formylmethionyl-tRNA deformylase - - - 0.00000000000000000000000000000000000000000000000000000000001108 216.0
CMS1_k127_801643_9 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000000000000000000000000001402 209.0
CMS1_k127_908106_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1320.0
CMS1_k127_908106_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.616e-282 875.0
CMS1_k127_908106_10 cytochrome C oxidoreductase subunit B - - - 0.000000000000000000000000000000000000000000004484 164.0
CMS1_k127_908106_11 - - - - 0.000000000000000000000004912 104.0
CMS1_k127_908106_12 Domain of unknown function (DUF2018) - - - 0.00000000000000000000001512 103.0
CMS1_k127_908106_14 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000815 54.0
CMS1_k127_908106_15 protein affecting phage T7 exclusion by the F plasmid K07113 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 - 0.000127 51.0
CMS1_k127_908106_2 Sulfite dehydrogenase (Cytochrome) subunit SorA apoprotein K07147 - - 2.683e-202 638.0
CMS1_k127_908106_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 462.0
CMS1_k127_908106_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 442.0
CMS1_k127_908106_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 420.0
CMS1_k127_908106_6 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 381.0
CMS1_k127_908106_7 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 315.0
CMS1_k127_908106_8 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 287.0
CMS1_k127_908106_9 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003896 262.0
CMS1_k127_921681_0 cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0 1065.0
CMS1_k127_921681_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.036e-243 756.0
CMS1_k127_921681_10 Glycosyl transferase family 90 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 331.0
CMS1_k127_921681_11 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 323.0
CMS1_k127_921681_12 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000002206 235.0
CMS1_k127_921681_13 O-acyltransferase activity K00661,K04042 - 2.3.1.157,2.3.1.79,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000007771 225.0
CMS1_k127_921681_14 GlutRNAGln amidotransferase subunit D K01424 - 3.5.1.1 0.00000000000000000000000000000000000002257 150.0
CMS1_k127_921681_15 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000001138 149.0
CMS1_k127_921681_16 Cytochrome c553 K08738 - - 0.00000000000000000000000000000000002148 137.0
CMS1_k127_921681_17 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000001086 123.0
CMS1_k127_921681_18 Cytochrome oxidase maturation protein - - - 0.0000000000000000000006325 96.0
CMS1_k127_921681_19 peptide-methionine (S)-S-oxide reductase activity - - - 0.0000000000002427 71.0
CMS1_k127_921681_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 3.418e-223 705.0
CMS1_k127_921681_20 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000831 78.0
CMS1_k127_921681_21 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000001016 66.0
CMS1_k127_921681_3 Sulfatase - - - 1.029e-217 693.0
CMS1_k127_921681_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 1.194e-215 682.0
CMS1_k127_921681_5 ADP-L-glycero-D-manno-heptose-6-epimerase K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 558.0
CMS1_k127_921681_6 heptosyltransferase ii K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 451.0
CMS1_k127_921681_7 lipopolysaccharide core region biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 432.0
CMS1_k127_921681_8 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 412.0
CMS1_k127_921681_9 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0003674,GO:0005488,GO:0005515,GO:0042802 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 374.0
CMS1_k127_937473_0 DNA polymerase K02337 - 2.7.7.7 0.0 1980.0
CMS1_k127_937473_1 - - - - 0.0 1234.0
CMS1_k127_937473_10 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 528.0
CMS1_k127_937473_11 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 475.0
CMS1_k127_937473_12 dehydrogenase K00076 - 1.1.1.159 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009851 456.0
CMS1_k127_937473_13 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 437.0
CMS1_k127_937473_14 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 375.0
CMS1_k127_937473_15 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 344.0
CMS1_k127_937473_16 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 325.0
CMS1_k127_937473_17 with different specificities (related to short-chain alcohol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 308.0
CMS1_k127_937473_18 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 302.0
CMS1_k127_937473_19 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004469 279.0
CMS1_k127_937473_2 Sulfatase - - - 1.179e-243 768.0
CMS1_k127_937473_20 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000009059 245.0
CMS1_k127_937473_21 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000776 198.0
CMS1_k127_937473_22 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000001256 198.0
CMS1_k127_937473_23 - - - - 0.0000000000000000000000000000000000000000001991 161.0
CMS1_k127_937473_24 Protein required for attachment to host cells - - - 0.00000000000000000000000000000000005338 139.0
CMS1_k127_937473_26 - - - - 0.0000000000008216 73.0
CMS1_k127_937473_28 Right handed beta helix region - - - 0.0002394 53.0
CMS1_k127_937473_3 Belongs to the peptidase M16 family - - - 6.166e-208 668.0
CMS1_k127_937473_4 Radical SAM - - - 7.667e-206 651.0
CMS1_k127_937473_5 domain, Protein - - - 2.039e-201 644.0
CMS1_k127_937473_6 Aminopeptidase I zinc metalloprotease (M18) K01267 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000534 592.0
CMS1_k127_937473_7 Major Facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 580.0
CMS1_k127_937473_8 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 556.0
CMS1_k127_937473_9 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 553.0
CMS1_k127_98237_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1077.0
CMS1_k127_98237_1 DNA helicase K03657 - 3.6.4.12 0.0 1054.0
CMS1_k127_98237_10 Potassium channel protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 569.0
CMS1_k127_98237_11 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 516.0
CMS1_k127_98237_12 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 517.0
CMS1_k127_98237_13 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 520.0
CMS1_k127_98237_14 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 509.0
CMS1_k127_98237_15 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 494.0
CMS1_k127_98237_16 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 488.0
CMS1_k127_98237_17 3-deoxy-d-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 479.0
CMS1_k127_98237_18 ABC transporter permease K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 456.0
CMS1_k127_98237_19 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 427.0
CMS1_k127_98237_2 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 7.473e-311 964.0
CMS1_k127_98237_20 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 417.0
CMS1_k127_98237_21 4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 416.0
CMS1_k127_98237_22 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 385.0
CMS1_k127_98237_23 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 385.0
CMS1_k127_98237_24 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 364.0
CMS1_k127_98237_25 Belongs to the 'phage' integrase family K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 360.0
CMS1_k127_98237_26 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 355.0
CMS1_k127_98237_27 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 353.0
CMS1_k127_98237_28 Belongs to the pseudouridine synthase RluA family K06179,K06180 - 5.4.99.23,5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 345.0
CMS1_k127_98237_29 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008804 338.0
CMS1_k127_98237_3 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 5.537e-281 868.0
CMS1_k127_98237_30 COG1579 Zn-ribbon protein possibly nucleic acid-binding K07164,K22391 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 329.0
CMS1_k127_98237_31 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 330.0
CMS1_k127_98237_32 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 319.0
CMS1_k127_98237_33 dinuclear metal center protein, YbgI K22391 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 314.0
CMS1_k127_98237_34 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 305.0
CMS1_k127_98237_35 dna polymerase iii K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 302.0
CMS1_k127_98237_36 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001146 283.0
CMS1_k127_98237_37 protein conserved in bacteria K09778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005612 259.0
CMS1_k127_98237_38 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001988 258.0
CMS1_k127_98237_39 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000002165 254.0
CMS1_k127_98237_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 6.577e-247 769.0
CMS1_k127_98237_40 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000517 237.0
CMS1_k127_98237_41 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000005847 233.0
CMS1_k127_98237_42 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000000000005432 220.0
CMS1_k127_98237_43 - K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000009394 210.0
CMS1_k127_98237_44 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000002544 208.0
CMS1_k127_98237_45 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000218 202.0
CMS1_k127_98237_46 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000000004701 173.0
CMS1_k127_98237_47 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000000006399 151.0
CMS1_k127_98237_49 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000006176 152.0
CMS1_k127_98237_5 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 6.506e-246 767.0
CMS1_k127_98237_50 Putative transmembrane protein (PGPGW) - - - 0.0000000000000000000000000000000000008323 145.0
CMS1_k127_98237_51 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000001639 138.0
CMS1_k127_98237_52 Histidine kinase K07648,K07679 - 2.7.13.3 0.0000000000000000000000000000000003436 147.0
CMS1_k127_98237_53 - - - - 0.000000000000000000000000000000005943 139.0
CMS1_k127_98237_54 - - - - 0.0000000000000000000000000000000103 128.0
CMS1_k127_98237_55 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000001243 115.0
CMS1_k127_98237_56 - - - - 0.000000000000000000000000002829 113.0
CMS1_k127_98237_57 Outer membrane protein beta-barrel domain - - - 0.000000000000000000004947 100.0
CMS1_k127_98237_59 PFAM Fimbrial assembly family protein - - - 0.000000000000000003097 91.0
CMS1_k127_98237_6 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.678e-226 707.0
CMS1_k127_98237_60 - - - - 0.00000000000000788 84.0
CMS1_k127_98237_61 - - - - 0.00000000000008417 78.0
CMS1_k127_98237_62 helix_turn_helix, Lux Regulon - - - 0.00000000008097 65.0
CMS1_k127_98237_63 Belongs to the UPF0109 family K06960 - - 0.0000005188 54.0
CMS1_k127_98237_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 3.523e-225 701.0
CMS1_k127_98237_8 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 4.273e-219 689.0
CMS1_k127_98237_9 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 4.294e-216 677.0