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Overview

ID MAG00307
Name CMS1_bin.120
Sample SMP0010
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanosarcinia
Order Methanosarcinales
Family Methanoperedenaceae
Genus Methanoperedens
Species
Assembly information
Completeness (%) 94.01
Contamination (%) 1.92
GC content (%) 42.0
N50 (bp) 17,532
Genome size (bp) 2,550,253

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2462

Gene name Description KEGG GOs EC E-value Score Sequence
CMS1_k127_1016221_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 443.0
CMS1_k127_1016221_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 416.0
CMS1_k127_1016221_2 PFAM transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003309 273.0
CMS1_k127_1016221_3 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001492 256.0
CMS1_k127_1021350_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.527e-248 773.0
CMS1_k127_1021350_1 type ii restriction enzyme K01155 - 3.1.21.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 484.0
CMS1_k127_1021350_10 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000004224 146.0
CMS1_k127_1021350_11 Universal stress protein family - - - 0.000000000000000000000000000000000005064 141.0
CMS1_k127_1021350_12 COG1361 S-layer domain - - - 0.0000000000000000000000000000001561 139.0
CMS1_k127_1021350_13 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000005001 117.0
CMS1_k127_1021350_14 Heavy metal translocating P-type atpase - - - 0.000000000000000000001759 103.0
CMS1_k127_1021350_15 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000001569 94.0
CMS1_k127_1021350_16 Protein of unknown function with PCYCGC motif - - - 0.00000000000000037 91.0
CMS1_k127_1021350_17 Thioredoxin-like - - - 0.00000000000001176 79.0
CMS1_k127_1021350_18 - - - - 0.0000000000003125 73.0
CMS1_k127_1021350_19 Protein of unknown function DUF131 - - - 0.00000000005386 65.0
CMS1_k127_1021350_2 COG1138 Cytochrome c biogenesis factor K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008883 363.0
CMS1_k127_1021350_20 type ii restriction enzyme K01155 - 3.1.21.4 0.0000000005569 61.0
CMS1_k127_1021350_21 Dodecin K09165 - - 0.00000005281 59.0
CMS1_k127_1021350_22 TIGRFAM TIGR00304 family protein - - - 0.0000003478 55.0
CMS1_k127_1021350_23 heme-binding sites - - - 0.00002432 55.0
CMS1_k127_1021350_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 317.0
CMS1_k127_1021350_4 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005778 263.0
CMS1_k127_1021350_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000001687 243.0
CMS1_k127_1021350_6 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000006889 201.0
CMS1_k127_1021350_7 Domain of unknown function (DUF366) K09139 - - 0.0000000000000000000000000000000000000000000000006358 181.0
CMS1_k127_1021350_8 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000002261 164.0
CMS1_k127_1021350_9 archaeal Zn-finger protein - - - 0.00000000000000000000000000000000000001144 156.0
CMS1_k127_1041090_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006542 526.0
CMS1_k127_1041090_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 410.0
CMS1_k127_1041090_10 WHG domain - - - 0.000000000000000000000000000000000000000000000000000004963 199.0
CMS1_k127_1041090_11 denitrification pathway - - - 0.000000000000000000000000000000000000000000005792 172.0
CMS1_k127_1041090_12 denitrification pathway - - - 0.0000000000000000000000000000000000397 146.0
CMS1_k127_1041090_13 - - - - 0.00000000000000000000008196 108.0
CMS1_k127_1041090_14 extracellular matrix structural constituent - - - 0.0000000000000000001308 102.0
CMS1_k127_1041090_15 FtsX-like permease family K09808 - - 0.00000000000006727 83.0
CMS1_k127_1041090_16 - - - - 0.0000000000001147 75.0
CMS1_k127_1041090_2 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 391.0
CMS1_k127_1041090_3 PFAM Circadian clock protein KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 345.0
CMS1_k127_1041090_4 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 333.0
CMS1_k127_1041090_5 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 304.0
CMS1_k127_1041090_6 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004172 281.0
CMS1_k127_1041090_7 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006339 267.0
CMS1_k127_1041090_8 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002749 254.0
CMS1_k127_1041090_9 Rhomboid family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000008595 222.0
CMS1_k127_1092255_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.332e-298 926.0
CMS1_k127_1092255_1 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 551.0
CMS1_k127_1092255_2 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 410.0
CMS1_k127_1092255_3 TIGRFAM TraB family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 402.0
CMS1_k127_1092255_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009089 384.0
CMS1_k127_1092255_5 serine threonine protein kinase K00870,K08884 - 2.7.1.37,2.7.11.1 0.0000000000000000002235 99.0
CMS1_k127_1093929_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 417.0
CMS1_k127_1093929_1 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 358.0
CMS1_k127_1093929_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001558 258.0
CMS1_k127_1093929_3 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000000001575 222.0
CMS1_k127_1093929_4 protein conserved in archaea K09746 - - 0.00000000000002491 74.0
CMS1_k127_1148000_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 6.521e-302 948.0
CMS1_k127_1148000_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 1.184e-258 812.0
CMS1_k127_1148000_10 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001484 283.0
CMS1_k127_1148000_11 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007271 273.0
CMS1_k127_1148000_12 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000001077 211.0
CMS1_k127_1148000_13 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000008532 168.0
CMS1_k127_1148000_14 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000000000187 155.0
CMS1_k127_1148000_15 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000002246 147.0
CMS1_k127_1148000_16 Winged helix-turn-helix DNA-binding - - - 0.0000000000000000000000000000000642 135.0
CMS1_k127_1148000_17 Uncharacterized protein conserved in archaea (DUF2180) - - - 0.000000000000000000000000007515 110.0
CMS1_k127_1148000_18 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000001247 113.0
CMS1_k127_1148000_19 Sulfurtransferase TusA K04085 - - 0.0000000000000000000001068 98.0
CMS1_k127_1148000_2 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 3.509e-198 627.0
CMS1_k127_1148000_20 PFAM Glutaredoxin K06191 - - 0.0000000000000000000022 96.0
CMS1_k127_1148000_21 4Fe-4S binding domain K00171 - 1.2.7.1 0.000000000000000000004925 104.0
CMS1_k127_1148000_22 Uncharacterized protein conserved in archaea (DUF2180) - - - 0.00000000000000000001438 93.0
CMS1_k127_1148000_23 - - - - 0.0000000000000000006729 93.0
CMS1_k127_1148000_24 Psort location Cytoplasmic, score K19824 - - 0.00000000000000003301 86.0
CMS1_k127_1148000_25 DsrE/DsrF-like family K07236 - - 0.000000000000001815 80.0
CMS1_k127_1148000_26 Domain of unknown function DUF302 - - - 0.0000000000001897 76.0
CMS1_k127_1148000_27 DsrE/DsrF-like family - - - 0.00000000002011 68.0
CMS1_k127_1148000_28 - - - - 0.00000000004285 74.0
CMS1_k127_1148000_29 Putative zinc- or iron-chelating domain K06940 - - 0.0000000008937 66.0
CMS1_k127_1148000_3 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 1.639e-194 612.0
CMS1_k127_1148000_30 - - - - 0.0000003795 54.0
CMS1_k127_1148000_4 Serine dehydrogenase proteinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 378.0
CMS1_k127_1148000_5 ferredoxin oxidoreductase K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 382.0
CMS1_k127_1148000_6 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 351.0
CMS1_k127_1148000_7 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 343.0
CMS1_k127_1148000_8 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 319.0
CMS1_k127_1148000_9 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 292.0
CMS1_k127_1164964_0 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 316.0
CMS1_k127_1164964_1 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000000009415 190.0
CMS1_k127_1228972_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1014.0
CMS1_k127_1228972_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 447.0
CMS1_k127_1228972_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 410.0
CMS1_k127_1228972_3 PFAM 4Fe-4S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 399.0
CMS1_k127_1228972_4 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 288.0
CMS1_k127_1228972_5 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000487 226.0
CMS1_k127_1228972_6 - - - - 0.0000000000000000000000000000000000000000003382 171.0
CMS1_k127_1228972_7 PFAM peptidase U32 K08303 - - 0.000000000000000000000000000000000000002313 154.0
CMS1_k127_1228972_8 PFAM ubiE COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000005619 149.0
CMS1_k127_1228972_9 Flavodoxin - - - 0.000000000000000000000000000202 119.0
CMS1_k127_1233912_0 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 546.0
CMS1_k127_1233912_1 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 346.0
CMS1_k127_1233912_2 Domain of unknown function (DUF1724) - - - 0.0000000000000000000000000000000000000000000000000000000000000000443 233.0
CMS1_k127_1233912_3 Peptidase M4 K01400 GO:0005575,GO:0005576 3.4.24.28 0.000005464 55.0
CMS1_k127_1243326_0 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 4.919e-226 707.0
CMS1_k127_1243326_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 9.877e-209 656.0
CMS1_k127_1243326_2 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007633 542.0
CMS1_k127_1243326_3 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 476.0
CMS1_k127_1243326_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001496 285.0
CMS1_k127_1243326_5 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000000000001346 115.0
CMS1_k127_1243326_6 mRNA binding K07339 - - 0.0000000000000000000000008777 106.0
CMS1_k127_1243326_7 Domain of unknown function (DUF4382) - - - 0.0000000000000000001107 95.0
CMS1_k127_1243326_8 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000006121 64.0
CMS1_k127_1243326_9 - - - - 0.0002535 46.0
CMS1_k127_139416_0 DEAD DEAH box helicase domain protein K03725 - - 3.183e-275 869.0
CMS1_k127_139416_1 Protein-export membrane protein SecD K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 529.0
CMS1_k127_139416_2 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 439.0
CMS1_k127_139416_3 Involved in protein export K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007626 273.0
CMS1_k127_1410801_0 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 2.021e-265 822.0
CMS1_k127_1410801_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 2.964e-254 795.0
CMS1_k127_1410801_10 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000001363 126.0
CMS1_k127_1410801_2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 559.0
CMS1_k127_1410801_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 478.0
CMS1_k127_1410801_4 CoB--CoM heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 387.0
CMS1_k127_1410801_5 Dihydrouridine synthase (Dus) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 339.0
CMS1_k127_1410801_6 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005998 250.0
CMS1_k127_1410801_7 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000005088 168.0
CMS1_k127_1410801_8 PFAM HhH-GPD family protein K07457 - - 0.0000000000000000000000000000000001599 138.0
CMS1_k127_1410801_9 Stress responsive A/B Barrel Domain - - - 0.000000000000000000000000000000002786 130.0
CMS1_k127_1411632_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 2.738e-221 693.0
CMS1_k127_1411632_1 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 495.0
CMS1_k127_1411632_2 Oxidoreductase family, C-terminal alpha/beta domain K18855 - 1.1.1.374 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 413.0
CMS1_k127_1411632_3 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 364.0
CMS1_k127_1411632_4 transferase hexapeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 295.0
CMS1_k127_1411632_5 - - - - 0.000000000000000000003099 100.0
CMS1_k127_1481234_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 8.336e-215 679.0
CMS1_k127_1481234_1 Flavoprotein K18853 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0042558,GO:0042559,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901283,GO:1901285,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:2001115,GO:2001116,GO:2001117,GO:2001118 1.5.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 289.0
CMS1_k127_1481234_2 - - - - 0.00000000000000000000000000000000000000000343 162.0
CMS1_k127_1481234_3 Sodium:dicarboxylate symporter family - - - 0.000000000000000000000000000000007296 130.0
CMS1_k127_1481234_4 PFAM Like-Sm ribonucleoprotein, core - - - 0.0000000000000000000000003863 106.0
CMS1_k127_1481234_5 B-block binding subunit of TFIIIC - - - 0.000000000000000000000003579 105.0
CMS1_k127_1481234_6 Belongs to the UPF0248 family K09715 - - 0.000000000009931 68.0
CMS1_k127_1481234_7 4 iron, 4 sulfur cluster binding - - - 0.0000008322 52.0
CMS1_k127_1547982_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007217 308.0
CMS1_k127_1547982_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003612 262.0
CMS1_k127_1547982_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000001787 264.0
CMS1_k127_1547982_3 DNA polymerase LigD, polymerase domain K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000009735 244.0
CMS1_k127_1547982_4 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000003932 203.0
CMS1_k127_1547982_5 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000001445 182.0
CMS1_k127_1547982_6 Protein of unknown function DUF72 - - - 0.00000000000000000000000000004869 119.0
CMS1_k127_1547982_7 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000005643 112.0
CMS1_k127_1547982_8 RibD C-terminal domain - - - 0.000000000000000003317 86.0
CMS1_k127_1552363_0 Patatin-like phospholipase K07001 - - 0.00000006569 55.0
CMS1_k127_158684_0 COGs COG2006 conserved - - - 0.0000000000000000000000000000003561 142.0
CMS1_k127_158684_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000001845 115.0
CMS1_k127_1594145_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 430.0
CMS1_k127_1594145_1 ABC-type phosphate transport system, periplasmic component K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007198 374.0
CMS1_k127_1594145_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 364.0
CMS1_k127_1594145_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036,K02068,K06857 - 3.6.3.27,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 355.0
CMS1_k127_1594145_4 phosphate transport system permease protein K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 333.0
CMS1_k127_1594145_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 296.0
CMS1_k127_1594145_6 Integral membrane protein DUF106 - - - 0.000000000000000000000000000000000000000000000000000000003111 205.0
CMS1_k127_1594145_7 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000001692 169.0
CMS1_k127_1594145_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000000004456 112.0
CMS1_k127_1594145_9 Possibly the antitoxin component of a - - - 0.0000105 53.0
CMS1_k127_1663129_0 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.0 1058.0
CMS1_k127_1663129_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 8.604e-228 713.0
CMS1_k127_1663129_2 AAA domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 329.0
CMS1_k127_1663129_3 KaiC - - - 0.0000000000000000000000000000000000000000000000000000428 198.0
CMS1_k127_1663129_4 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear K00195 - - 0.00000000000000000000000000000000000000000001029 169.0
CMS1_k127_1663129_5 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000003685 161.0
CMS1_k127_1663129_6 - - - - 0.00000000000000000000000000003057 132.0
CMS1_k127_1663129_7 - - - - 0.000000003503 63.0
CMS1_k127_1663129_8 EamA-like transporter family - - - 0.000000009949 66.0
CMS1_k127_170612_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 473.0
CMS1_k127_170612_1 ATP-grasp domain K06914 - 6.3.4.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 292.0
CMS1_k127_170612_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005853 284.0
CMS1_k127_170612_3 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001524 229.0
CMS1_k127_170612_4 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000000000000000000000000000000000000000000000003126 213.0
CMS1_k127_170612_5 integral membrane protein K07027 - - 0.0000000000000000002275 100.0
CMS1_k127_1727342_0 4Fe-4S dicluster domain - - - 5.484e-262 821.0
CMS1_k127_1727342_1 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 579.0
CMS1_k127_1727342_10 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.000003562 59.0
CMS1_k127_1727342_2 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 543.0
CMS1_k127_1727342_3 PHB de-polymerase C-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 441.0
CMS1_k127_1727342_4 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 396.0
CMS1_k127_1727342_5 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 323.0
CMS1_k127_1727342_6 TrkA-C domain K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 301.0
CMS1_k127_1727342_7 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000009855 263.0
CMS1_k127_1727342_8 TIGRFAM poly(R)-hydroxyalkanoic acid synthase, class III, PhaE subunit - GO:0008150,GO:0008152,GO:0009058,GO:0042618,GO:0042619,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.000000000000224 78.0
CMS1_k127_1727342_9 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000001577 63.0
CMS1_k127_172950_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1264.0
CMS1_k127_172950_1 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 3.057e-202 646.0
CMS1_k127_172950_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 413.0
CMS1_k127_172950_11 Probable transposase K07496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 411.0
CMS1_k127_172950_12 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 392.0
CMS1_k127_172950_13 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 374.0
CMS1_k127_172950_14 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 340.0
CMS1_k127_172950_15 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 318.0
CMS1_k127_172950_16 Protein of unknown function (DUF1464) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009332 286.0
CMS1_k127_172950_17 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001444 254.0
CMS1_k127_172950_18 Transcriptional regulator K07722 - - 0.00000000000000000000000000000000000000000000000000000000000071 213.0
CMS1_k127_172950_19 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000001402 217.0
CMS1_k127_172950_2 phosphoesterase RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 544.0
CMS1_k127_172950_20 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000103 199.0
CMS1_k127_172950_21 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000001514 200.0
CMS1_k127_172950_22 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000002234 189.0
CMS1_k127_172950_23 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000001019 182.0
CMS1_k127_172950_24 PFAM PUA domain containing protein K07398 - - 0.0000000000000000000000000000000000000000000000000128 184.0
CMS1_k127_172950_25 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000003466 142.0
CMS1_k127_172950_26 serine-type aminopeptidase activity K14475 - - 0.0000000000000000000000000000000001668 142.0
CMS1_k127_172950_27 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.000000000000000000000000000001879 123.0
CMS1_k127_172950_28 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.00000000000000000000000000003485 123.0
CMS1_k127_172950_29 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.00000000000000000000000000005965 120.0
CMS1_k127_172950_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 533.0
CMS1_k127_172950_30 Protein of unknown function DUF86 - - - 0.00000000000000000000000005189 112.0
CMS1_k127_172950_31 - - - - 0.0000000000000000000000001515 113.0
CMS1_k127_172950_32 Chlorite dismutase - - - 0.0000000000000000000000001802 108.0
CMS1_k127_172950_33 Urm1 (Ubiquitin related modifier) K03636 - - 0.000000000000000000169 91.0
CMS1_k127_172950_34 PFAM Exonuclease VII small subunit K03602 - 3.1.11.6 0.00000000000000006875 82.0
CMS1_k127_172950_35 but it may be involved in stabilization of the trimeric complex - - - 0.0000000000004363 70.0
CMS1_k127_172950_36 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.000000001637 60.0
CMS1_k127_172950_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 527.0
CMS1_k127_172950_5 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 521.0
CMS1_k127_172950_6 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 520.0
CMS1_k127_172950_7 TIGRFAM small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 505.0
CMS1_k127_172950_8 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 425.0
CMS1_k127_172950_9 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 422.0
CMS1_k127_1800350_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 545.0
CMS1_k127_1800350_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 445.0
CMS1_k127_1800350_10 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008591 246.0
CMS1_k127_1800350_11 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002208 251.0
CMS1_k127_1800350_12 Enoyl-(Acyl carrier protein) reductase K00059,K18009,K19548 - 1.1.1.100,1.1.1.304,1.1.1.385,1.1.1.76 0.000000000000000000000000000000000000000000000000000000000000009836 224.0
CMS1_k127_1800350_13 ribosomal protein S15 K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000005242 181.0
CMS1_k127_1800350_14 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000128 171.0
CMS1_k127_1800350_15 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000002094 167.0
CMS1_k127_1800350_16 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000000000000000000004388 162.0
CMS1_k127_1800350_17 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.0000000000000000000000000000000000000372 146.0
CMS1_k127_1800350_18 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000001757 138.0
CMS1_k127_1800350_19 cheY-homologous receiver domain - - - 0.0000000000000000000000000004979 120.0
CMS1_k127_1800350_2 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009865 432.0
CMS1_k127_1800350_20 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.0000000000000000000000002423 105.0
CMS1_k127_1800350_21 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.00000000000000005817 81.0
CMS1_k127_1800350_22 - - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 - 0.000000003064 60.0
CMS1_k127_1800350_23 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0000000041 61.0
CMS1_k127_1800350_24 - - - - 0.00000002977 59.0
CMS1_k127_1800350_25 Pfam:DUF1628 - - - 0.0001095 50.0
CMS1_k127_1800350_3 AAA domain (Cdc48 subfamily) K07392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 418.0
CMS1_k127_1800350_4 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 392.0
CMS1_k127_1800350_5 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 340.0
CMS1_k127_1800350_6 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 338.0
CMS1_k127_1800350_7 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 289.0
CMS1_k127_1800350_8 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 286.0
CMS1_k127_1800350_9 KaiC K07331 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002657 248.0
CMS1_k127_1801313_0 Required for chromosome condensation and partitioning K03529 - - 9.372e-207 657.0
CMS1_k127_1801313_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 2.548e-199 628.0
CMS1_k127_1801313_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 315.0
CMS1_k127_1801313_3 - - - - 0.00000000000006636 82.0
CMS1_k127_1819597_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1167.0
CMS1_k127_1819597_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 9.821e-218 690.0
CMS1_k127_1819597_10 septum formation protein Maf K06287 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - 0.00000000000000000000000000000000000000000000000003331 185.0
CMS1_k127_1819597_11 PFAM conserved - - - 0.00000000000000000000000000000000000000000091 161.0
CMS1_k127_1819597_12 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000007091 147.0
CMS1_k127_1819597_13 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000000006673 136.0
CMS1_k127_1819597_14 COG3634 Alkyl hydroperoxide reductase, large subunit - - - 0.00000000000000000004766 93.0
CMS1_k127_1819597_15 Domain of unknown function (DUF1894) - - - 0.00000000000009192 74.0
CMS1_k127_1819597_16 Putative zinc- or iron-chelating domain K06940 - - 0.00003278 52.0
CMS1_k127_1819597_17 - - - - 0.00008955 49.0
CMS1_k127_1819597_18 cell wall organization - - - 0.0001569 48.0
CMS1_k127_1819597_2 Uncharacterized protein conserved in archaea (DUF2114) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 587.0
CMS1_k127_1819597_3 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 445.0
CMS1_k127_1819597_4 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 300.0
CMS1_k127_1819597_5 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 295.0
CMS1_k127_1819597_6 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 289.0
CMS1_k127_1819597_7 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 282.0
CMS1_k127_1819597_8 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001493 254.0
CMS1_k127_1819597_9 Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000001039 198.0
CMS1_k127_1832283_0 toxin activity - - - 0.00008138 53.0
CMS1_k127_1847904_0 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 372.0
CMS1_k127_1847904_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 343.0
CMS1_k127_1847904_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 287.0
CMS1_k127_1847904_3 - - - - 0.000000000000000000000000000000000000000000000000000000000002771 212.0
CMS1_k127_1847904_4 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000002726 173.0
CMS1_k127_1847904_5 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000001476 168.0
CMS1_k127_1847904_6 - - - - 0.00000000000000000000000000000000000000001114 168.0
CMS1_k127_1847904_7 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000002436 128.0
CMS1_k127_1847904_8 Alpha/beta hydrolase family K10216 - 3.7.1.9 0.000000000000000000000000008692 121.0
CMS1_k127_1847904_9 Putative adhesin - - - 0.0000000851 61.0
CMS1_k127_1865673_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.628e-229 729.0
CMS1_k127_1865673_1 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 471.0
CMS1_k127_1865673_2 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000008665 248.0
CMS1_k127_1865673_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000009828 224.0
CMS1_k127_1865673_4 Radical SAM domain protein K09711 - - 0.000000000000000000000000003339 116.0
CMS1_k127_1865673_5 - - - - 0.000000000000000000006586 102.0
CMS1_k127_1865673_6 - - - - 0.000006674 55.0
CMS1_k127_1870499_0 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000146 166.0
CMS1_k127_1870499_1 Cartilage oligomeric matrix protein K04659 GO:0000902,GO:0001501,GO:0001503,GO:0001932,GO:0001934,GO:0001936,GO:0001938,GO:0001968,GO:0002020,GO:0002682,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005198,GO:0005201,GO:0005488,GO:0005496,GO:0005499,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005912,GO:0005924,GO:0005927,GO:0006928,GO:0006950,GO:0007155,GO:0007160,GO:0007275,GO:0007399,GO:0007517,GO:0007610,GO:0008150,GO:0008201,GO:0008284,GO:0008289,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010941,GO:0012505,GO:0014812,GO:0016043,GO:0016203,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0019220,GO:0019222,GO:0019842,GO:0019899,GO:0021700,GO:0022008,GO:0022603,GO:0022607,GO:0022610,GO:0030030,GO:0030054,GO:0030055,GO:0030154,GO:0030182,GO:0030198,GO:0030334,GO:0030335,GO:0030855,GO:0031012,GO:0031175,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0031589,GO:0031594,GO:0032101,GO:0032103,GO:0032268,GO:0032270,GO:0032501,GO:0032502,GO:0032879,GO:0032989,GO:0032990,GO:0032991,GO:0033554,GO:0033555,GO:0033627,GO:0034103,GO:0034976,GO:0035265,GO:0035989,GO:0036094,GO:0040007,GO:0040011,GO:0040012,GO:0040017,GO:0042127,GO:0042325,GO:0042327,GO:0042981,GO:0043062,GO:0043066,GO:0043067,GO:0043069,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043236,GO:0043237,GO:0043394,GO:0043395,GO:0043931,GO:0043933,GO:0044085,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045202,GO:0045765,GO:0045937,GO:0046872,GO:0048265,GO:0048266,GO:0048468,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048646,GO:0048666,GO:0048699,GO:0048705,GO:0048731,GO:0048736,GO:0048799,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048870,GO:0050678,GO:0050679,GO:0050730,GO:0050731,GO:0050789,GO:0050793,GO:0050794,GO:0050839,GO:0050840,GO:0050896,GO:0050920,GO:0050921,GO:0051093,GO:0051171,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051259,GO:0051260,GO:0051270,GO:0051272,GO:0051451,GO:0051674,GO:0051716,GO:0060173,GO:0060231,GO:0060255,GO:0060343,GO:0060346,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060429,GO:0060538,GO:0060548,GO:0061053,GO:0061061,GO:0061383,GO:0061430,GO:0061448,GO:0062023,GO:0065003,GO:0065007,GO:0070161,GO:0070977,GO:0071603,GO:0071622,GO:0071624,GO:0071695,GO:0071840,GO:0080090,GO:0090022,GO:0090023,GO:0090136,GO:0097159,GO:0097367,GO:0098609,GO:0098868,GO:0120036,GO:0120039,GO:1901342,GO:1901343,GO:1901681,GO:1902622,GO:1902624,GO:2000026,GO:2000145,GO:2000147,GO:2000181 - 0.000000000000000000008329 108.0
CMS1_k127_1879878_0 Protein of unknown function (DUF1616) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000977 312.0
CMS1_k127_1879878_1 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K13014 GO:0005575,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0042221,GO:0050896 - 0.0000000000000000000000000000548 126.0
CMS1_k127_1879878_2 Group 1 family - - - 0.00000000000000000000000003425 122.0
CMS1_k127_1879878_3 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000002621 106.0
CMS1_k127_1879878_4 CAAX protease self-immunity K07052 - - 0.000000000000000005404 94.0
CMS1_k127_1881221_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 7.45e-312 985.0
CMS1_k127_1881221_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.828e-301 938.0
CMS1_k127_1881221_2 coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K00125 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 519.0
CMS1_k127_1881221_3 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 336.0
CMS1_k127_1881221_4 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000003311 265.0
CMS1_k127_1881221_5 PFAM Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000005974 185.0
CMS1_k127_1881221_6 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000006298 184.0
CMS1_k127_1881221_7 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000771 132.0
CMS1_k127_1881221_8 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000693 132.0
CMS1_k127_1886982_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 5.331e-219 691.0
CMS1_k127_1886982_1 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 556.0
CMS1_k127_1886982_10 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000009984 249.0
CMS1_k127_1886982_11 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000009761 200.0
CMS1_k127_1886982_12 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000001116 191.0
CMS1_k127_1886982_13 - - - - 0.00000000000000000000000000000000000000000000005349 173.0
CMS1_k127_1886982_14 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000008395 173.0
CMS1_k127_1886982_15 Transcriptional regulator - - - 0.000000000000000000000000000000000002463 141.0
CMS1_k127_1886982_16 - - - - 0.00000000000000000000000000000000002716 139.0
CMS1_k127_1886982_17 Protein of unknown function (DUF2551) - - - 0.000000000000000000000000000000197 126.0
CMS1_k127_1886982_18 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000000000006773 123.0
CMS1_k127_1886982_19 Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.00000000000000000000000000008536 119.0
CMS1_k127_1886982_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 521.0
CMS1_k127_1886982_20 membrane-associated protein domain - - - 0.0000000000000000000000000001381 129.0
CMS1_k127_1886982_21 - - - - 0.000000000000000000000000598 108.0
CMS1_k127_1886982_22 PFAM plasmid stabilization system K06218 - - 0.00000000000000000000000204 104.0
CMS1_k127_1886982_23 - - - - 0.00000000000261 68.0
CMS1_k127_1886982_24 Protein of unknown function (DUF2283) - - - 0.000000000003325 68.0
CMS1_k127_1886982_26 Protein of unknown function (DUF2283) - - - 0.00000000001631 66.0
CMS1_k127_1886982_27 Domain of unknown function (DUF4258) - - - 0.0000000001956 64.0
CMS1_k127_1886982_28 Protein of unknown function (DUF2283) - - - 0.000000001622 61.0
CMS1_k127_1886982_29 Domain of unknown function (DUF4258) - - - 0.0000004958 55.0
CMS1_k127_1886982_3 PFAM Radical SAM domain protein K07129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 377.0
CMS1_k127_1886982_30 Domain of unknown function (DUF4258) - - - 0.000001761 53.0
CMS1_k127_1886982_31 Domain of unknown function (DUF4258) - - - 0.000003043 49.0
CMS1_k127_1886982_32 Domain of unknown function (DUF4258) - - - 0.000008697 50.0
CMS1_k127_1886982_4 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 359.0
CMS1_k127_1886982_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 337.0
CMS1_k127_1886982_6 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 312.0
CMS1_k127_1886982_7 archaeal coiled-coil protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 306.0
CMS1_k127_1886982_8 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 300.0
CMS1_k127_1886982_9 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 284.0
CMS1_k127_1909257_0 PFAM ATPase, BadF BadG BcrA BcrD type - - - 4.66e-196 618.0
CMS1_k127_1909257_1 Belongs to the UPF0288 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 501.0
CMS1_k127_1909257_2 methanogenesis marker protein 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 389.0
CMS1_k127_1909257_3 PFAM ABC transporter K00400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 297.0
CMS1_k127_1909257_4 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001356 280.0
CMS1_k127_1909257_5 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000001364 221.0
CMS1_k127_1909257_6 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.00000000000000000000000000000000000000000000000000000000001922 209.0
CMS1_k127_1909257_7 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.000000000000000000000000000000000000001694 154.0
CMS1_k127_1909257_8 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.00000000000000000000000000000000001509 140.0
CMS1_k127_1909257_9 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000004861 122.0
CMS1_k127_1911809_0 SMART Elongator protein 3 MiaB NifB - - - 4.084e-272 848.0
CMS1_k127_1911809_1 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 8.022e-213 664.0
CMS1_k127_1911809_10 Pfam:DUF1628 - - - 0.0000000000503 70.0
CMS1_k127_1911809_11 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.00000000006224 63.0
CMS1_k127_1911809_12 - - - - 0.00000004448 58.0
CMS1_k127_1911809_2 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 440.0
CMS1_k127_1911809_3 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008807 413.0
CMS1_k127_1911809_4 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 378.0
CMS1_k127_1911809_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 358.0
CMS1_k127_1911809_6 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000001155 232.0
CMS1_k127_1911809_7 Domain of unknown function (DUF4347) - - - 0.00000000000000009698 93.0
CMS1_k127_1911809_8 Family of unknown function (DUF5371) - - - 0.000000000000003016 79.0
CMS1_k127_1911809_9 Pfam:DUF1628 - - - 0.00000000000716 72.0
CMS1_k127_1927290_0 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 554.0
CMS1_k127_1927290_1 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 513.0
CMS1_k127_1927290_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 325.0
CMS1_k127_1927290_3 MscS Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 302.0
CMS1_k127_1927290_4 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000776 286.0
CMS1_k127_1927290_5 PFAM MscS Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000549 165.0
CMS1_k127_1927290_6 COG0668 Small-conductance mechanosensitive channel K16052 - - 0.00000000000000000000000000000008971 132.0
CMS1_k127_1927290_7 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000002473 114.0
CMS1_k127_1930016_0 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007519 329.0
CMS1_k127_1930016_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004779 260.0
CMS1_k127_1930016_2 PFAM phosphatidate cytidylyltransferase - - - 0.0000000000000000000000000000000000000000000000001693 183.0
CMS1_k127_1930016_3 Methyltransferase type 11 - - - 0.000000000004866 66.0
CMS1_k127_1930016_4 integral membrane protein K07027 - - 0.0000001353 63.0
CMS1_k127_194971_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1290.0
CMS1_k127_194971_1 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 474.0
CMS1_k127_194971_2 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 457.0
CMS1_k127_194971_3 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 299.0
CMS1_k127_194971_4 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000007285 211.0
CMS1_k127_1972966_0 Transketolase, pyrimidine binding domain K00162,K21417 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 423.0
CMS1_k127_1972966_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 426.0
CMS1_k127_1972966_2 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 379.0
CMS1_k127_1972966_3 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 368.0
CMS1_k127_1972966_4 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 295.0
CMS1_k127_1972966_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000001644 207.0
CMS1_k127_1972966_7 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.000000000000000000005986 93.0
CMS1_k127_1972966_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000236 83.0
CMS1_k127_1981857_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 3.852e-320 995.0
CMS1_k127_1981857_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.223e-262 817.0
CMS1_k127_1981857_10 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 375.0
CMS1_k127_1981857_11 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 365.0
CMS1_k127_1981857_12 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 351.0
CMS1_k127_1981857_13 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 349.0
CMS1_k127_1981857_14 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 348.0
CMS1_k127_1981857_15 Rio2, N-terminal K07179 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 335.0
CMS1_k127_1981857_16 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 290.0
CMS1_k127_1981857_17 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002337 282.0
CMS1_k127_1981857_18 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000318 265.0
CMS1_k127_1981857_19 SAM-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007258 263.0
CMS1_k127_1981857_2 PFAM type II secretion system protein E K07332 - - 2.425e-213 675.0
CMS1_k127_1981857_20 KaiC K07331 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001273 248.0
CMS1_k127_1981857_21 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000001545 246.0
CMS1_k127_1981857_22 Cytochrome b(N-terminal)/b6/petB K03887 - - 0.00000000000000000000000000000000000000000000000000000000000000000001799 239.0
CMS1_k127_1981857_23 COG0500 SAM-dependent methyltransferases K17462 - - 0.000000000000000000000000000000000000000000000000000000000000000002371 234.0
CMS1_k127_1981857_24 PQQ enzyme repeat - - - 0.000000000000000000000000000000000000000000000000000000000003104 225.0
CMS1_k127_1981857_25 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000003075 214.0
CMS1_k127_1981857_26 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000005535 190.0
CMS1_k127_1981857_27 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000001008 168.0
CMS1_k127_1981857_28 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000001608 171.0
CMS1_k127_1981857_29 PFAM regulatory protein, ArsR K07721 - - 0.0000000000000000000000000000000000000000003671 165.0
CMS1_k127_1981857_3 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009675 590.0
CMS1_k127_1981857_30 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000000000000005865 154.0
CMS1_k127_1981857_31 CheC inhibitor of MCP methylation K03410 - - 0.0000000000000000000000000000000008041 138.0
CMS1_k127_1981857_32 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000001361 133.0
CMS1_k127_1981857_33 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000000000000000262 124.0
CMS1_k127_1981857_34 Archaebacterial flagellin K07330 - - 0.00000000000000000000000000002926 121.0
CMS1_k127_1981857_35 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000000001725 119.0
CMS1_k127_1981857_36 Chorismate mutase type II K04782 - 4.2.99.21 0.000000000000000000000000002373 114.0
CMS1_k127_1981857_37 Domain of unknown function (DUF1805) - - - 0.0000000000000000000000002271 108.0
CMS1_k127_1981857_38 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000004545 109.0
CMS1_k127_1981857_39 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000000000000000001817 108.0
CMS1_k127_1981857_4 Protein of unknown function (DUF460) K09150 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 573.0
CMS1_k127_1981857_40 - - - - 0.0000000000000000000006219 98.0
CMS1_k127_1981857_41 Rieske 2Fe-2S - - - 0.0000000000000000000006401 101.0
CMS1_k127_1981857_42 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000004339 100.0
CMS1_k127_1981857_43 - - - - 0.00000000000001951 81.0
CMS1_k127_1981857_44 denitrification pathway - - - 0.0000000000003678 80.0
CMS1_k127_1981857_45 Cytochrome b subunit of the bc complex K02637 - - 0.0000000000008347 74.0
CMS1_k127_1981857_46 Glutaredoxin-like domain (DUF836) - - - 0.000000000002451 70.0
CMS1_k127_1981857_47 PFAM response regulator receiver - - - 0.000000000006056 74.0
CMS1_k127_1981857_49 formate dehydrogenase K03620 - - 0.000000000054 73.0
CMS1_k127_1981857_5 Chemotaxis protein CheA K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 565.0
CMS1_k127_1981857_50 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000005658 49.0
CMS1_k127_1981857_51 PFAM flagellin K07329 - - 0.000007459 53.0
CMS1_k127_1981857_6 PFAM AAA ATPase central domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 530.0
CMS1_k127_1981857_7 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 458.0
CMS1_k127_1981857_8 type II secretion system protein K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 467.0
CMS1_k127_1981857_9 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 388.0
CMS1_k127_2011933_0 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.257e-235 737.0
CMS1_k127_2011933_1 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 620.0
CMS1_k127_2011933_2 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000304 258.0
CMS1_k127_2011933_3 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000002111 199.0
CMS1_k127_2011933_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000001762 180.0
CMS1_k127_2021998_0 PFAM Aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 552.0
CMS1_k127_2021998_1 PFAM regulatory protein AsnC Lrp family - - - 0.000000000000000000000000000000000000000000000000000000000001876 214.0
CMS1_k127_2021998_2 Phage integrase family - - - 0.00000003327 58.0
CMS1_k127_2052783_0 PFAM Integrase catalytic K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 401.0
CMS1_k127_2052783_1 Esterase-like activity of phytase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 391.0
CMS1_k127_2052783_2 transposase activity - - - 0.00000000000000000000000000000000006899 137.0
CMS1_k127_2052783_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000004576 103.0
CMS1_k127_2053440_0 GDP dissociation inhibitor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 328.0
CMS1_k127_2053440_1 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000002049 221.0
CMS1_k127_2053440_2 Domain of unknown function DUF11 - - - 0.0000126 58.0
CMS1_k127_2068705_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 568.0
CMS1_k127_2068705_1 TIGRFAM Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 523.0
CMS1_k127_2068705_10 - - - - 0.0000000000000000000000002572 117.0
CMS1_k127_2068705_2 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 375.0
CMS1_k127_2068705_3 PFAM thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000004624 237.0
CMS1_k127_2068705_4 Appr-1-p processing domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000001368 218.0
CMS1_k127_2068705_5 Segregation and condensation protein ScpA K05896 - - 0.0000000000000000000000000000000000000000000000000000000003085 210.0
CMS1_k127_2068705_6 cellulose binding - - - 0.0000000000000000000000000000000000000000000000001633 194.0
CMS1_k127_2068705_7 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000005626 160.0
CMS1_k127_2068705_8 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000009575 153.0
CMS1_k127_2068705_9 membrane-associated protein domain - - - 0.000000000000000000000000001393 119.0
CMS1_k127_2100703_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1489.0
CMS1_k127_2100703_1 DEAD DEAH box helicase domain protein K03724 - - 0.0 1090.0
CMS1_k127_2100703_10 - - - - 0.0000000000008378 77.0
CMS1_k127_2100703_2 Belongs to the MCM family K10726 - - 7.682e-270 846.0
CMS1_k127_2100703_3 Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 483.0
CMS1_k127_2100703_4 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 431.0
CMS1_k127_2100703_5 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 440.0
CMS1_k127_2100703_6 archaeal coiled-coil protein - - - 0.000000000000000000000000000000000000000000000000000000000000002896 232.0
CMS1_k127_2100703_7 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.0000000000000000000000000000000000000000000004519 172.0
CMS1_k127_2100703_8 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000003278 104.0
CMS1_k127_2100703_9 Belongs to the peptidase S16 family K06870 - - 0.0000000000000006363 88.0
CMS1_k127_2105465_0 PFAM Radical SAM domain protein K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 610.0
CMS1_k127_2105465_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000006327 129.0
CMS1_k127_2105465_2 NAD(P)H dehydrogenase (quinone) activity K03809 - 1.6.5.2 0.000000000000000000000000597 110.0
CMS1_k127_2105465_3 CBS domain - - - 0.0000000000000000000005841 100.0
CMS1_k127_2105465_4 - - - - 0.000000000000001167 82.0
CMS1_k127_2105465_5 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.0000000002485 72.0
CMS1_k127_212573_0 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K02014,K16087 - - 0.000000000000000000000000000000000000000001681 174.0
CMS1_k127_2130809_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001172 278.0
CMS1_k127_2130809_1 COGs COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995,K11957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008349 255.0
CMS1_k127_2130809_2 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001445 248.0
CMS1_k127_2130809_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000142 248.0
CMS1_k127_2130809_4 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000003638 226.0
CMS1_k127_2130809_5 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000001567 179.0
CMS1_k127_2131278_0 Type I restriction enzyme R protein N terminus (HSDR_N) - - - 0.0 1153.0
CMS1_k127_2131278_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1050.0
CMS1_k127_2131278_10 - - - - 0.0000000001329 64.0
CMS1_k127_2131278_11 peroxisome targeting signal receptor K12261,K13342 GO:0000268,GO:0003674,GO:0005048,GO:0005052,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0015919,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016558,GO:0016560,GO:0017038,GO:0019395,GO:0019752,GO:0030258,GO:0030674,GO:0031090,GO:0031903,GO:0032787,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034440,GO:0034613,GO:0042277,GO:0042579,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043574,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044743,GO:0045184,GO:0046395,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0055114,GO:0060090,GO:0065002,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071806,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0098588,GO:0098805,GO:1901575,GO:1990351,GO:1990415,GO:1990429 - 0.0000002266 64.0
CMS1_k127_2131278_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.851e-298 926.0
CMS1_k127_2131278_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 427.0
CMS1_k127_2131278_4 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 438.0
CMS1_k127_2131278_5 TPR Domain containing protein - - - 0.000000000000000000000000000000000000000002493 177.0
CMS1_k127_2131278_6 Protein of unknown function DUF84 - - - 0.000000000000000000000000000000000000002744 152.0
CMS1_k127_2131278_7 - - - - 0.00000000000000000000000000004254 123.0
CMS1_k127_2131278_8 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 0.0000000000000000000000000003484 114.0
CMS1_k127_2131278_9 - - - - 0.00000000000000001009 91.0
CMS1_k127_2167008_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 2.799e-213 675.0
CMS1_k127_2167008_1 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 539.0
CMS1_k127_2167008_2 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000004858 166.0
CMS1_k127_2167008_3 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000000004198 130.0
CMS1_k127_2167008_4 - - - - 0.000000000000000000004872 96.0
CMS1_k127_2167008_5 PFAM plasmid stabilization system K06218 - - 0.000006704 49.0
CMS1_k127_2176532_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000002604 253.0
CMS1_k127_2176532_1 - K01448 - 3.5.1.28 0.000000000000000000000000000000000000652 161.0
CMS1_k127_2189059_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.887e-272 846.0
CMS1_k127_2189059_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.103e-235 743.0
CMS1_k127_2189059_10 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000004057 211.0
CMS1_k127_2189059_11 Chlorophyllase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000001307 207.0
CMS1_k127_2189059_12 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000000004909 104.0
CMS1_k127_2189059_13 PFAM dihydropteroate synthase, DHPS - - - 0.0000000000000000000005069 97.0
CMS1_k127_2189059_14 - - - - 0.00003355 52.0
CMS1_k127_2189059_2 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 4.7e-219 689.0
CMS1_k127_2189059_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 560.0
CMS1_k127_2189059_4 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 515.0
CMS1_k127_2189059_5 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 495.0
CMS1_k127_2189059_6 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 475.0
CMS1_k127_2189059_7 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005911 269.0
CMS1_k127_2189059_8 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001938 242.0
CMS1_k127_2189059_9 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000001662 233.0
CMS1_k127_2233532_0 Phage tail sheath C-terminal domain K06907 - - 1.084e-202 649.0
CMS1_k127_2233532_1 phage tail region protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 325.0
CMS1_k127_2233532_2 PFAM T4 bacteriophage base plate protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000005935 241.0
CMS1_k127_2269875_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 454.0
CMS1_k127_2269875_1 ergosterol biosynthetic process K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 272.0
CMS1_k127_2269875_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000001121 196.0
CMS1_k127_2269875_3 - - - - 0.0000000000000000000000000000000000000000000000001351 180.0
CMS1_k127_2269875_4 TspO/MBR family K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000004875 145.0
CMS1_k127_2269875_5 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000005512 117.0
CMS1_k127_2269875_6 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000000004872 96.0
CMS1_k127_2269875_7 PFAM transcriptional regulator PadR family protein - - - 0.00000000000000000003244 94.0
CMS1_k127_2269875_8 Cytochrome c554 and c-prime - - - 0.000000000001436 79.0
CMS1_k127_22865_0 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000000000000000000000000000000006423 204.0
CMS1_k127_22865_1 - - - - 0.00000000000000000000000000000000000000000000003909 183.0
CMS1_k127_22865_2 Peptidase domain protein - - - 0.000000000074 65.0
CMS1_k127_2331652_0 PFAM oxidoreductase nitrogenase, component 1 K02586 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 595.0
CMS1_k127_2331652_1 Radical SAM ThiC family K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 525.0
CMS1_k127_2331652_10 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001675 249.0
CMS1_k127_2331652_11 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000007358 219.0
CMS1_k127_2331652_12 RimK-like ATPgrasp N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000001144 219.0
CMS1_k127_2331652_13 Belongs to the P(II) protein family K02589 - - 0.0000000000000000000000000000000000000005059 151.0
CMS1_k127_2331652_14 Belongs to the P(II) protein family K02590 - - 0.0000000000000000000000000000000000002684 144.0
CMS1_k127_2331652_15 PFAM ribosomal protein S8E K02995 - - 0.00000000000000000000000000000000001248 139.0
CMS1_k127_2331652_16 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.00000000000000000000000000000000006899 137.0
CMS1_k127_2331652_17 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 - - - 0.000000000000000000006305 98.0
CMS1_k127_2331652_18 4Fe-4S dicluster domain - - - 0.000000000000000003075 87.0
CMS1_k127_2331652_19 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000003624 77.0
CMS1_k127_2331652_2 Pterin binding enzyme K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 474.0
CMS1_k127_2331652_20 PFAM CBS domain containing protein K06213 - - 0.0001089 49.0
CMS1_k127_2331652_3 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 432.0
CMS1_k127_2331652_4 Belongs to the NifD NifK NifE NifN family K02591 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 433.0
CMS1_k127_2331652_5 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 374.0
CMS1_k127_2331652_6 RimK-like ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 361.0
CMS1_k127_2331652_7 Methylenetetrahydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 316.0
CMS1_k127_2331652_8 TIGRFAM F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 311.0
CMS1_k127_2331652_9 Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001893 271.0
CMS1_k127_2447685_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 2.143e-265 833.0
CMS1_k127_2447685_1 DEAD DEAH box helicase K03654 - 3.6.4.12 7.175e-248 786.0
CMS1_k127_2447685_10 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000007225 104.0
CMS1_k127_2447685_11 Belongs to the 'phage' integrase family - - - 0.000000000000000000002658 94.0
CMS1_k127_2447685_12 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A K02944 - - 0.0000000000005584 70.0
CMS1_k127_2447685_13 PFAM aminotransferase, class I K00812,K10907 - 2.6.1.1 0.00000002666 55.0
CMS1_k127_2447685_14 - - - - 0.0001341 45.0
CMS1_k127_2447685_2 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 1.36e-199 631.0
CMS1_k127_2447685_3 Arsenical pump membrane protein K03893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 423.0
CMS1_k127_2447685_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 417.0
CMS1_k127_2447685_5 PFAM Conserved TM helix repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 351.0
CMS1_k127_2447685_6 Conserved hypothetical ATP binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 266.0
CMS1_k127_2447685_7 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000001393 254.0
CMS1_k127_2447685_8 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001938 249.0
CMS1_k127_2447685_9 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.0000000000000000000000000004236 115.0
CMS1_k127_2497132_0 HsdM N-terminal domain - - - 6.506e-241 751.0
CMS1_k127_2497132_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 608.0
CMS1_k127_2497132_10 COG NOG10855 non supervised orthologous group - - - 0.00000000000000000000000004553 109.0
CMS1_k127_2497132_11 Transposase IS200 like K07491 - - 0.000000000000000000001131 100.0
CMS1_k127_2497132_12 Zinc-binding dehydrogenase - - - 0.0000000000000008445 79.0
CMS1_k127_2497132_13 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.0000000000000051 78.0
CMS1_k127_2497132_2 Sodium:neurotransmitter symporter family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 504.0
CMS1_k127_2497132_3 NADPH quinone reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 395.0
CMS1_k127_2497132_4 Pfam:DUF137 K09722 - 6.3.2.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 300.0
CMS1_k127_2497132_5 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 306.0
CMS1_k127_2497132_6 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009691 267.0
CMS1_k127_2497132_7 PFAM GHMP kinase K06982 - 2.7.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000001434 254.0
CMS1_k127_2497132_8 Peptidase M36 - - - 0.00000000000000000000000000000000000000000000000000000000000000229 241.0
CMS1_k127_2497132_9 PFAM N-6 DNA methylase K03427 - 2.1.1.72 0.000000000000000000000000000000001043 131.0
CMS1_k127_2529248_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.823e-216 679.0
CMS1_k127_2529248_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 579.0
CMS1_k127_2529248_10 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 287.0
CMS1_k127_2529248_11 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001978 282.0
CMS1_k127_2529248_12 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000001768 252.0
CMS1_k127_2529248_13 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000276 247.0
CMS1_k127_2529248_14 Functions by promoting the formation of the first peptide bond K03263 - - 0.00000000000000000000000000000000000000000000000000002133 190.0
CMS1_k127_2529248_15 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.0000000000000000000000000000000000000000851 158.0
CMS1_k127_2529248_16 eRF1 domain 2 - - - 0.0000000000000000000000000000000000000004294 161.0
CMS1_k127_2529248_17 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000001607 119.0
CMS1_k127_2529248_18 binds to the 23S rRNA K02921 - - 0.000000000000000000000000001893 114.0
CMS1_k127_2529248_19 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006464,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051604,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000000000000186 106.0
CMS1_k127_2529248_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 392.0
CMS1_k127_2529248_20 - - - - 0.00000000000000000000001268 103.0
CMS1_k127_2529248_21 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.0000000000000000000618 89.0
CMS1_k127_2529248_22 Probably involved in the biogenesis of the ribosome K14561 - - 0.00000000000002505 78.0
CMS1_k127_2529248_24 Gar1/Naf1 RNA binding region K07569 - - 0.000000000001191 70.0
CMS1_k127_2529248_3 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 389.0
CMS1_k127_2529248_4 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 366.0
CMS1_k127_2529248_5 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 362.0
CMS1_k127_2529248_6 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 349.0
CMS1_k127_2529248_7 PFAM elongation factor Tu domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 353.0
CMS1_k127_2529248_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 326.0
CMS1_k127_2529248_9 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 301.0
CMS1_k127_2556715_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 435.0
CMS1_k127_2556715_1 Belongs to the UPF0216 family K09737 - - 0.00000000000000000000000002296 113.0
CMS1_k127_2556715_2 integral membrane protein - - - 0.000000000000009681 82.0
CMS1_k127_2556715_3 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.000001267 53.0
CMS1_k127_261318_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 6.395e-203 640.0
CMS1_k127_261318_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 514.0
CMS1_k127_261318_2 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 445.0
CMS1_k127_261318_3 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000002165 154.0
CMS1_k127_261318_4 Nucleotidyltransferase domain K07075 - - 0.00000003341 56.0
CMS1_k127_265694_0 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K00657,K03825 - 2.3.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 338.0
CMS1_k127_265694_1 TIGRFAM methionine-R-sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000001364 194.0
CMS1_k127_265694_2 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000002305 136.0
CMS1_k127_2692608_0 Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 405.0
CMS1_k127_2692608_1 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 376.0
CMS1_k127_2692608_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000002632 178.0
CMS1_k127_2692608_3 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000002152 129.0
CMS1_k127_2692608_4 GDYXXLXY protein - - - 0.0000000000000000000006731 102.0
CMS1_k127_2692608_5 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000007318 83.0
CMS1_k127_2692608_6 Protein of unknown function (DUF2892) - - - 0.0000002101 55.0
CMS1_k127_2699002_0 PFAM aminotransferase class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 479.0
CMS1_k127_2699002_1 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 446.0
CMS1_k127_2699002_10 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000343 212.0
CMS1_k127_2699002_12 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000003378 201.0
CMS1_k127_2699002_13 Prokaryotic homologs of the JAB domain - - - 0.000000000000000000000000000000000000000611 152.0
CMS1_k127_2699002_14 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000001114 142.0
CMS1_k127_2699002_15 PFAM Thioredoxin K03671 - - 0.000000000000000000000000000003389 123.0
CMS1_k127_2699002_16 Aldolase K11645 - 4.1.2.13 0.000000000000000000000000002814 121.0
CMS1_k127_2699002_17 - - - - 0.00000000000000000002941 101.0
CMS1_k127_2699002_18 - - - - 0.0001317 49.0
CMS1_k127_2699002_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 421.0
CMS1_k127_2699002_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 382.0
CMS1_k127_2699002_4 Metallo-beta-lactamase superfamily K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 363.0
CMS1_k127_2699002_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 333.0
CMS1_k127_2699002_6 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 334.0
CMS1_k127_2699002_7 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 304.0
CMS1_k127_2699002_8 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000001278 244.0
CMS1_k127_2699002_9 SCO1/SenC - - - 0.000000000000000000000000000000000000000000000000000000000004744 211.0
CMS1_k127_2700539_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.662e-232 730.0
CMS1_k127_2700539_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.453e-231 754.0
CMS1_k127_2700539_10 protein N-acetylglucosaminyltransferase activity K12600 - - 0.000000000000000000000000000000000000000000000000007928 188.0
CMS1_k127_2700539_11 binds to the 23S rRNA K02929 - - 0.00000000000000000000000000000000000000105 149.0
CMS1_k127_2700539_12 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000001148 150.0
CMS1_k127_2700539_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000003513 130.0
CMS1_k127_2700539_14 PFAM Ribosomal protein S27E K02978 - - 0.0000000000000000000008495 96.0
CMS1_k127_2700539_15 protein conserved in archaea K09723 - - 0.0000000000000006609 87.0
CMS1_k127_2700539_16 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000008812 69.0
CMS1_k127_2700539_2 Translation initiation factor 2 alpha subunit K03237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 329.0
CMS1_k127_2700539_3 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 319.0
CMS1_k127_2700539_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007449 309.0
CMS1_k127_2700539_5 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 294.0
CMS1_k127_2700539_6 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 293.0
CMS1_k127_2700539_7 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000001206 231.0
CMS1_k127_2700539_8 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008339 255.0
CMS1_k127_2700539_9 domain protein K01992,K06994 - - 0.0000000000000000000000000000000000000000000000000000000006799 210.0
CMS1_k127_2706898_0 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 3.204e-229 718.0
CMS1_k127_2706898_1 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 572.0
CMS1_k127_2706898_2 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 335.0
CMS1_k127_2706898_3 SatD family (SatD) - - - 0.000000000000000000000000000000000000000000002316 172.0
CMS1_k127_2706898_4 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000000000000000002085 126.0
CMS1_k127_2706898_5 HEPN domain - - - 0.000000000000000000000001367 108.0
CMS1_k127_2706898_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000001466 98.0
CMS1_k127_2706898_7 Nucleotidyltransferase domain - - - 0.00000000000000153 83.0
CMS1_k127_2706898_8 - - - - 0.00000000002511 64.0
CMS1_k127_2709226_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.192e-295 922.0
CMS1_k127_2709226_1 Pyruvate phosphate dikinase, PEP pyruvate binding domain K01007 - 2.7.9.2 3.751e-260 828.0
CMS1_k127_2709226_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000812 238.0
CMS1_k127_2709226_11 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000001031 204.0
CMS1_k127_2709226_12 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000008425 194.0
CMS1_k127_2709226_13 Helix-turn-helix XRE-family like proteins K03627 - - 0.0000000000000000000000000000000000000000000001502 172.0
CMS1_k127_2709226_14 cellular manganese ion homeostasis - - - 0.000000000000000000000000000001061 126.0
CMS1_k127_2709226_15 peptidase - - - 0.00000000000000000002344 98.0
CMS1_k127_2709226_16 Roadblock LC7 family protein K07131 - - 0.0000000000000000004866 91.0
CMS1_k127_2709226_17 SNARE associated Golgi protein K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.0000000000000000005861 93.0
CMS1_k127_2709226_19 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000001389 79.0
CMS1_k127_2709226_2 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 584.0
CMS1_k127_2709226_20 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000005708 83.0
CMS1_k127_2709226_21 - - - - 0.00000000005182 70.0
CMS1_k127_2709226_3 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 547.0
CMS1_k127_2709226_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 542.0
CMS1_k127_2709226_5 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 532.0
CMS1_k127_2709226_6 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 424.0
CMS1_k127_2709226_7 Domain of unknown function (DUF373) K08975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 353.0
CMS1_k127_2709226_8 Leucine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 344.0
CMS1_k127_2709226_9 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 322.0
CMS1_k127_2722829_0 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 367.0
CMS1_k127_2722829_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 329.0
CMS1_k127_2722829_10 Arm DNA-binding domain - - - 0.000000575 61.0
CMS1_k127_2722829_2 S4 RNA-binding domain K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000004265 231.0
CMS1_k127_2722829_3 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000001044 222.0
CMS1_k127_2722829_4 PAS domain - - - 0.000000000000000000000000000000000000000000000000000001664 207.0
CMS1_k127_2722829_5 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.00000000000000000000000000000000000000000000000004832 189.0
CMS1_k127_2722829_6 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit K00441,K22174 - 1.1.98.4,1.12.98.1 0.000000000000000000000000000000000000000000006231 177.0
CMS1_k127_2722829_7 - - - - 0.000000000000000000000000000000000000000000147 165.0
CMS1_k127_2722829_8 PFAM SAICAR synthetase K01756,K01923 - 4.3.2.2,6.3.2.6 0.0000000000000000000006846 100.0
CMS1_k127_2722829_9 - - - - 0.0000000005149 61.0
CMS1_k127_2726112_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.4e-223 701.0
CMS1_k127_2726112_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 480.0
CMS1_k127_2726112_10 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000002987 257.0
CMS1_k127_2726112_11 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003725 252.0
CMS1_k127_2726112_12 Transcription elongation factor Spt5 K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000131 225.0
CMS1_k127_2726112_13 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000001363 226.0
CMS1_k127_2726112_14 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000001422 218.0
CMS1_k127_2726112_15 TIGRFAM ribosomal protein L30P K02907 - - 0.000000000000000000000000000000000000000000000000000000001213 203.0
CMS1_k127_2726112_16 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000002735 203.0
CMS1_k127_2726112_17 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000006302 200.0
CMS1_k127_2726112_18 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000009398 197.0
CMS1_k127_2726112_19 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000000000004984 181.0
CMS1_k127_2726112_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 471.0
CMS1_k127_2726112_20 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000001201 182.0
CMS1_k127_2726112_21 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000818 178.0
CMS1_k127_2726112_22 binds to the 23S rRNA K02885 - - 0.00000000000000000000000000000000000000000000000817 175.0
CMS1_k127_2726112_23 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000000000001542 163.0
CMS1_k127_2726112_24 toxin activity - - - 0.00000000000000000000000000000000000000000001591 172.0
CMS1_k127_2726112_25 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000001755 164.0
CMS1_k127_2726112_26 Belongs to the eukaryotic ribosomal protein eL32 family K02912 - - 0.0000000000000000000000000000000000000000002961 166.0
CMS1_k127_2726112_27 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000000000000001454 159.0
CMS1_k127_2726112_28 toxin activity - - - 0.00000000000000000000000000000000000000006833 170.0
CMS1_k127_2726112_29 - - - - 0.000000000000000000000000000000000000006685 152.0
CMS1_k127_2726112_3 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 439.0
CMS1_k127_2726112_30 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.00000000000000000000000000000000001252 138.0
CMS1_k127_2726112_31 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000172,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005732,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000344 93.0
CMS1_k127_2726112_32 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.000000000000000000209 87.0
CMS1_k127_2726112_33 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000000004398 88.0
CMS1_k127_2726112_34 - - - - 0.000000000000005063 81.0
CMS1_k127_2726112_35 - - - - 0.00000000000001446 83.0
CMS1_k127_2726112_36 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.00000000000004836 73.0
CMS1_k127_2726112_37 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000000000148 73.0
CMS1_k127_2726112_38 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000002309 71.0
CMS1_k127_2726112_39 - - - - 0.00002967 53.0
CMS1_k127_2726112_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 432.0
CMS1_k127_2726112_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 425.0
CMS1_k127_2726112_6 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 346.0
CMS1_k127_2726112_7 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008867 308.0
CMS1_k127_2726112_8 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 301.0
CMS1_k127_2726112_9 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 297.0
CMS1_k127_2734503_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 593.0
CMS1_k127_2734503_1 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 376.0
CMS1_k127_2734503_2 NAD(P)H dehydrogenase (quinone) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001924 246.0
CMS1_k127_2734503_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000001476 239.0
CMS1_k127_2749267_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 304.0
CMS1_k127_2749267_1 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000201 179.0
CMS1_k127_2749267_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03673 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071236,GO:0140096 - 0.00000000001008 74.0
CMS1_k127_27681_0 HMGL-like K01649 - 2.3.3.13 1.088e-209 659.0
CMS1_k127_27681_1 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 533.0
CMS1_k127_27681_10 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000001263 104.0
CMS1_k127_27681_11 Copper binding proteins, plastocyanin/azurin family - - - 0.00000004534 63.0
CMS1_k127_27681_2 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 312.0
CMS1_k127_27681_3 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002297 284.0
CMS1_k127_27681_4 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000142 273.0
CMS1_k127_27681_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000004039 227.0
CMS1_k127_27681_6 PFAM O-methyltransferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000002944 211.0
CMS1_k127_27681_7 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000001786 203.0
CMS1_k127_27681_8 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000424 182.0
CMS1_k127_27681_9 zinc ion binding - - - 0.000000000000000000000000000000000000000003714 162.0
CMS1_k127_2778003_0 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 361.0
CMS1_k127_2778003_1 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008341 353.0
CMS1_k127_2778003_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000001059 165.0
CMS1_k127_2778003_3 toxin-antitoxin pair type II binding - - - 0.000000000000000000000002377 104.0
CMS1_k127_2778003_4 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000002319 80.0
CMS1_k127_2786071_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 404.0
CMS1_k127_2786071_1 shikimate kinase activity K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 341.0
CMS1_k127_2786071_2 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006085 277.0
CMS1_k127_2786071_3 Acetyl xylan esterase (AXE1) K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000447 257.0
CMS1_k127_2786071_4 chorismate mutase K04093 - 5.4.99.5 0.00000000000000000000003438 101.0
CMS1_k127_2790879_0 Putative transposase DNA-binding domain - - - 0.000004709 59.0
CMS1_k127_2802396_0 GDP dissociation inhibitor - - - 0.000000000000000000000000000000000000000000000000000000000004136 211.0
CMS1_k127_2802396_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000001694 90.0
CMS1_k127_2820770_0 PFAM restriction modification system DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000000000000000000000000000000000000000000001556 226.0
CMS1_k127_2820770_1 Protein of unknown function DUF86 K07075 - - 0.0000000000000000000000000000004057 125.0
CMS1_k127_2820770_2 - - - - 0.0000000000000000000000000000006143 128.0
CMS1_k127_2820770_3 DNA polymerase beta domain protein region K07075 - - 0.000000000000000000000003755 104.0
CMS1_k127_2820770_4 - K07039 - - 0.00004727 54.0
CMS1_k127_2824038_0 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 548.0
CMS1_k127_2824038_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 357.0
CMS1_k127_2824038_10 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000003424 179.0
CMS1_k127_2824038_11 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000001399 141.0
CMS1_k127_2824038_12 Radical SAM domain protein K01012 - 2.8.1.6 0.0000000000000000000000000000003612 127.0
CMS1_k127_2824038_2 Methyltransferase K15429 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 302.0
CMS1_k127_2824038_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007785 291.0
CMS1_k127_2824038_4 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000002917 246.0
CMS1_k127_2824038_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000001253 226.0
CMS1_k127_2824038_6 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000003472 214.0
CMS1_k127_2824038_7 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000000000000000000000000000479 201.0
CMS1_k127_2824038_8 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000006388 202.0
CMS1_k127_2824038_9 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000002219 184.0
CMS1_k127_2844711_0 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 8.571e-309 959.0
CMS1_k127_2844711_1 COG1522 Transcriptional regulators - - - 0.000000000000000000001424 102.0
CMS1_k127_2852698_0 AMP-binding enzyme - - - 9.375e-232 722.0
CMS1_k127_2852698_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000004651 229.0
CMS1_k127_2852698_2 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000001449 215.0
CMS1_k127_2852698_3 homolog of gamma-carboxymuconolactone decarboxylase subunit - - - 0.000000000000000000000000000000000000008612 147.0
CMS1_k127_2852698_4 Chlorite dismutase - - - 0.000000000000000000000004912 104.0
CMS1_k127_2852698_5 Transposase DDE domain - - - 0.00000000000000005692 88.0
CMS1_k127_2852698_6 Flavodoxin - - - 0.000000000000004415 75.0
CMS1_k127_2852698_7 - - - - 0.0003405 46.0
CMS1_k127_287258_0 DGC domain - - - 0.0000000000000000000000000000000000000000000000000000000001896 207.0
CMS1_k127_287258_1 - - - - 0.0000000000005512 71.0
CMS1_k127_287258_2 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000002415 58.0
CMS1_k127_2874396_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 376.0
CMS1_k127_2874396_1 PFAM UspA - - - 0.000000000000000001937 89.0
CMS1_k127_2874396_2 Protein of unknown function (DUF1646) - - - 0.000009652 51.0
CMS1_k127_2890460_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.69e-210 661.0
CMS1_k127_2890460_1 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 616.0
CMS1_k127_2890460_10 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000001149 198.0
CMS1_k127_2890460_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000171 170.0
CMS1_k127_2890460_12 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000001075 162.0
CMS1_k127_2890460_13 PFAM BFD-like 2Fe-2S binding domain - - - 0.000000000000000000000000000000000397 138.0
CMS1_k127_2890460_14 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000726 134.0
CMS1_k127_2890460_15 Glycine cleavage H-protein K02437 - - 0.00000000000000000000000000000001365 131.0
CMS1_k127_2890460_16 protein conserved in archaea - - - 0.00000000000000000000000000000006293 126.0
CMS1_k127_2890460_17 Rhodanese Homology Domain - - - 0.000000000000000000000000000014 122.0
CMS1_k127_2890460_18 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000002965 119.0
CMS1_k127_2890460_19 ZIP Zinc transporter K16267 - - 0.00000000000000000000000000005276 125.0
CMS1_k127_2890460_2 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 538.0
CMS1_k127_2890460_20 Protein of unknown function (DUF429) K09147 - - 0.000000000000000000000000007518 118.0
CMS1_k127_2890460_21 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000003 102.0
CMS1_k127_2890460_22 response to heat K07090 - - 0.00000000000000000007057 99.0
CMS1_k127_2890460_23 - - - - 0.0000000000000000008653 89.0
CMS1_k127_2890460_24 - - - - 0.000000000000008124 76.0
CMS1_k127_2890460_25 MTH865-like family - - - 0.00000000003237 64.0
CMS1_k127_2890460_26 oxidoreductase - - - 0.0000000001558 72.0
CMS1_k127_2890460_27 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.0000000001991 64.0
CMS1_k127_2890460_28 - - - - 0.000000006422 61.0
CMS1_k127_2890460_29 Putative cell wall binding repeat 2 - - - 0.0000009813 58.0
CMS1_k127_2890460_3 PFAM peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 537.0
CMS1_k127_2890460_30 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.0001601 48.0
CMS1_k127_2890460_4 Peptidase propeptide and YPEB domain K01399 - 3.4.24.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 368.0
CMS1_k127_2890460_5 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 326.0
CMS1_k127_2890460_6 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 301.0
CMS1_k127_2890460_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004042 278.0
CMS1_k127_2890460_8 regulatory protein, arsR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001198 267.0
CMS1_k127_2890460_9 Haloacid dehalogenase-like hydrolase K01838 - 5.4.2.6 0.000000000000000000000000000000000000000000000000000000000000000000006162 240.0
CMS1_k127_2899154_0 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 517.0
CMS1_k127_2899154_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 500.0
CMS1_k127_2899154_10 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000007055 160.0
CMS1_k127_2899154_11 - - - - 0.00000000000000000000000000000000000002485 145.0
CMS1_k127_2899154_12 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.00000000000000000000000001732 111.0
CMS1_k127_2899154_13 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000003342 93.0
CMS1_k127_2899154_15 structural constituent of ribosome K02924 - - 0.00000000000001576 74.0
CMS1_k127_2899154_18 - - - - 0.0000001956 54.0
CMS1_k127_2899154_2 PFAM Radical SAM domain protein K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 430.0
CMS1_k127_2899154_3 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 342.0
CMS1_k127_2899154_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 315.0
CMS1_k127_2899154_5 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008284 280.0
CMS1_k127_2899154_6 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002986 248.0
CMS1_k127_2899154_7 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006069 243.0
CMS1_k127_2899154_8 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001423 237.0
CMS1_k127_2899154_9 Hydrolase Family 16 - - - 0.0000000000000000000000000000000000000000000000000000005932 210.0
CMS1_k127_2900405_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1229.0
CMS1_k127_2900405_1 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 1.078e-225 710.0
CMS1_k127_2900405_10 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000000002972 89.0
CMS1_k127_2900405_11 Peptidase, U32 family - - - 0.000000000000000004582 85.0
CMS1_k127_2900405_12 - K08982 - - 0.000000000000003747 77.0
CMS1_k127_2900405_13 Roadblock LC7 family protein K07131 - - 0.000000000000007401 79.0
CMS1_k127_2900405_2 TGS domain protein K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009226 512.0
CMS1_k127_2900405_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 494.0
CMS1_k127_2900405_4 - K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 366.0
CMS1_k127_2900405_5 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004529 275.0
CMS1_k127_2900405_6 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006489 267.0
CMS1_k127_2900405_7 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.0000000000000000000000000000000000000000000000000000000246 204.0
CMS1_k127_2900405_8 Cytochrome c K02275 - 1.9.3.1 0.0000000000000000000000001195 112.0
CMS1_k127_2900405_9 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000000000000000001106 106.0
CMS1_k127_292311_0 cheY-homologous receiver domain K07658 - - 0.000000000000000000000000000000000000000000000000000222 189.0
CMS1_k127_292311_1 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000005035 182.0
CMS1_k127_292311_2 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000001004 169.0
CMS1_k127_292311_3 - - - - 0.00000000000000000000000000151 114.0
CMS1_k127_292311_4 Metallopeptidase family M24 - - - 0.000000005028 66.0
CMS1_k127_2925717_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 333.0
CMS1_k127_2925717_1 TIGRFAM PAS domain S-box - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 317.0
CMS1_k127_2925717_2 binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001245 283.0
CMS1_k127_2925717_3 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008125 275.0
CMS1_k127_2925717_4 transcriptional regulator, AsnC family - - - 0.000000000000000000000000000000000000000000000000000000000008679 212.0
CMS1_k127_2925717_5 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000007469 149.0
CMS1_k127_2925717_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000000002713 117.0
CMS1_k127_2929898_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 1.318e-261 818.0
CMS1_k127_2929898_1 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 4.27e-221 693.0
CMS1_k127_2929898_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 361.0
CMS1_k127_2929898_11 PFAM triphosphoribosyl-dephospho-CoA protein K05966 - 2.4.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 299.0
CMS1_k127_2929898_12 Putative Fe-S cluster K11260 - - 0.0000000000000000000000000000000000000000000000000000002264 198.0
CMS1_k127_2929898_14 Cupin - - - 0.00000000000000000000000000000000000000000004299 164.0
CMS1_k127_2929898_15 Protein of unknown function (DUF447) K09154 - - 0.000000000000000000000000000000000000000001128 162.0
CMS1_k127_2929898_16 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000004341 162.0
CMS1_k127_2929898_17 Molydopterin dinucleotide binding domain K00203 - 1.2.7.12 0.0000000000000000000000000000005285 126.0
CMS1_k127_2929898_18 Pfam:UPF0118 - - - 0.00000000000000000000000002472 121.0
CMS1_k127_2929898_19 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000001047 107.0
CMS1_k127_2929898_2 PFAM Radical SAM domain protein K06937 - - 7.036e-196 621.0
CMS1_k127_2929898_21 - - - - 0.000000000000003285 88.0
CMS1_k127_2929898_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 608.0
CMS1_k127_2929898_4 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 566.0
CMS1_k127_2929898_5 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 529.0
CMS1_k127_2929898_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 466.0
CMS1_k127_2929898_7 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 456.0
CMS1_k127_2929898_8 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 394.0
CMS1_k127_2929898_9 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 393.0
CMS1_k127_2944920_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004819 267.0
CMS1_k127_2944920_1 DEAD DEAH box helicase domain protein K05592,K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000008395 228.0
CMS1_k127_2944920_2 nucleic acid-binding protein, contains PIN domain - - - 0.00000000000000000000001214 106.0
CMS1_k127_2944920_3 Uncharacterised protein family (UPF0175) - - - 0.0000000000000000001078 91.0
CMS1_k127_294820_0 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 326.0
CMS1_k127_294820_1 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000001565 192.0
CMS1_k127_294820_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000008609 181.0
CMS1_k127_2957931_0 Flavodoxin-like fold K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000001578 212.0
CMS1_k127_2957931_1 - - - - 0.0000000000007321 74.0
CMS1_k127_2957931_2 peptidyl-tyrosine sulfation - - - 0.00000000328 64.0
CMS1_k127_2957931_3 Transposase DDE domain K07492 - - 0.00008963 47.0
CMS1_k127_2967086_0 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000008792 142.0
CMS1_k127_2975331_0 PFAM Peptidase S24 S26A S26B, conserved region K13280 - 3.4.21.89 0.000000000000000000000000002994 120.0
CMS1_k127_2975331_1 - - - - 0.0000000000000000000005145 106.0
CMS1_k127_2975331_2 - - - - 0.0000000000008307 79.0
CMS1_k127_2975331_3 - - - - 0.0001707 49.0
CMS1_k127_2975331_4 heat shock protein binding - - - 0.0002104 51.0
CMS1_k127_2977277_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 526.0
CMS1_k127_2977277_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 462.0
CMS1_k127_2977277_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000008348 213.0
CMS1_k127_2981752_0 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 289.0
CMS1_k127_2981752_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000006734 160.0
CMS1_k127_2981752_2 Family of unknown function (DUF5371) - - - 0.000004617 50.0
CMS1_k127_2986756_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1195.0
CMS1_k127_2986756_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 547.0
CMS1_k127_2986756_10 Protein of unknown function (DUF473) K09135 - - 0.000000000000000000000337 101.0
CMS1_k127_2986756_11 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000002635 61.0
CMS1_k127_2986756_12 glycosyl transferase, family 39 - - - 0.000533 53.0
CMS1_k127_2986756_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 520.0
CMS1_k127_2986756_3 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 480.0
CMS1_k127_2986756_4 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 426.0
CMS1_k127_2986756_5 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 306.0
CMS1_k127_2986756_6 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 304.0
CMS1_k127_2986756_7 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000005769 215.0
CMS1_k127_2986756_8 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000002468 171.0
CMS1_k127_2986756_9 Type I restriction modification DNA specificity domain K01154 - 3.1.21.3 0.000000000000000000000006148 103.0
CMS1_k127_3013680_0 Protein of unknown function (DUF1616) - - - 0.000000000000000000000000000000000000000000000000000000000003818 218.0
CMS1_k127_3013680_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000006302 188.0
CMS1_k127_3013680_2 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000009088 165.0
CMS1_k127_3013680_3 Protein of unknown function (DUF3485) - - - 0.00000000111 69.0
CMS1_k127_3013680_4 ATP hydrolysis coupled proton transport - - - 0.000000001181 61.0
CMS1_k127_3024979_0 sulfate adenylyltransferase K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 485.0
CMS1_k127_3024979_1 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 416.0
CMS1_k127_3024979_2 Reduction of activated sulfate into sulfite K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 369.0
CMS1_k127_3024979_3 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006685 264.0
CMS1_k127_3024979_4 Transport of potassium into the cell K03549 - - 0.00000000000000000000000000000005269 126.0
CMS1_k127_3031024_0 PFAM ABC transporter K00400 - - 4.306e-194 614.0
CMS1_k127_3031024_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 340.0
CMS1_k127_3031024_2 HAF family - - - 0.0000000000000000000000000000000000000000000000000000000000004344 227.0
CMS1_k127_3031024_3 O-methyltransferase activity K00543,K13169 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008172,GO:0008757,GO:0009058,GO:0009059,GO:0009308,GO:0009309,GO:0009987,GO:0010467,GO:0010817,GO:0016740,GO:0016741,GO:0017096,GO:0017144,GO:0018130,GO:0019438,GO:0019538,GO:0030186,GO:0030187,GO:0032259,GO:0034641,GO:0034645,GO:0034754,GO:0042401,GO:0042430,GO:0042435,GO:0042445,GO:0042446,GO:0042802,GO:0042803,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046483,GO:0046983,GO:0048519,GO:0050789,GO:0050793,GO:0051093,GO:0051239,GO:0051241,GO:0065007,GO:0065008,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1905939,GO:1905940,GO:2000018,GO:2000019,GO:2000026,GO:2000241,GO:2000242 2.1.1.4 0.00000000000000000000000000000000000000000000000000000004081 209.0
CMS1_k127_3031024_4 PFAM Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000000000000000000000526 184.0
CMS1_k127_303988_0 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000003378 113.0
CMS1_k127_303988_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000003174 66.0
CMS1_k127_3060965_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 5.433e-204 653.0
CMS1_k127_3060965_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002735 259.0
CMS1_k127_3060965_2 Thiamine-binding protein - - - 0.00000000000000000000000159 106.0
CMS1_k127_3060965_3 transcriptional - - - 0.000000000000005491 79.0
CMS1_k127_3060965_4 transcription factor binding K03407,K07641,K12132,K13924 - 2.1.1.80,2.7.11.1,2.7.13.3,3.1.1.61 0.00001349 52.0
CMS1_k127_3092475_0 conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001561 222.0
CMS1_k127_3092475_1 PFAM PKD domain - - - 0.00000000000000009589 93.0
CMS1_k127_3092475_3 - - - - 0.00000007876 59.0
CMS1_k127_3092475_4 Proton-conducting membrane transporter K12137 - - 0.0000003559 55.0
CMS1_k127_3092475_5 Belongs to the peptidase S8 family K14645 - - 0.0000005949 61.0
CMS1_k127_3092475_6 PFAM PKD domain containing protein K11751 - 3.1.3.5,3.6.1.45 0.00000817 51.0
CMS1_k127_3227036_0 Male sterility protein K01710,K01784 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 413.0
CMS1_k127_3227036_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 336.0
CMS1_k127_3227036_2 peptidase activity, acting on L-amino acid peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000003039 267.0
CMS1_k127_3227036_3 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000001085 219.0
CMS1_k127_3227036_4 Oxidoreductase family, C-terminal alpha/beta domain K18855 - 1.1.1.374 0.000000000000000000000000000000000001648 141.0
CMS1_k127_3227036_5 Fibronectin type 3 domain - - - 0.000000000000000004006 102.0
CMS1_k127_3227036_6 LamG domain protein jellyroll fold domain protein K03418,K07151 - 2.4.99.18,3.5.1.56 0.0000000000000005606 94.0
CMS1_k127_3242339_0 PHB de-polymerase C-terminus K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 431.0
CMS1_k127_3242339_1 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 322.0
CMS1_k127_3242339_2 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.0000000000000000000000000000000000000000000000000000004161 203.0
CMS1_k127_3242339_3 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.000000000000001751 84.0
CMS1_k127_3242339_4 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.000001505 60.0
CMS1_k127_3247355_0 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 317.0
CMS1_k127_3247355_1 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000001545 239.0
CMS1_k127_3247355_2 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000113 175.0
CMS1_k127_3247355_3 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.0000000000000000000000000000000000000000001873 165.0
CMS1_k127_3247355_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000003907 106.0
CMS1_k127_3247355_5 formate dehydrogenase K00127 - - 0.0000000000000000001597 95.0
CMS1_k127_3256237_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 6.967e-258 807.0
CMS1_k127_3256237_1 Transport of potassium into the cell K03549 - - 3.696e-236 741.0
CMS1_k127_3256237_10 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000004839 181.0
CMS1_k127_3256237_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000005114 179.0
CMS1_k127_3256237_12 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000000002368 181.0
CMS1_k127_3256237_13 - - - - 0.0000000000000000000000000000000000000000000001819 189.0
CMS1_k127_3256237_14 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000002295 124.0
CMS1_k127_3256237_15 4 iron, 4 sulfur cluster binding K11260 - - 0.000000000000000000002412 96.0
CMS1_k127_3256237_16 - - - - 0.000000000000000000007787 106.0
CMS1_k127_3256237_17 Domain of unknown function (DUF378) K09779 - - 0.000000000000000000353 88.0
CMS1_k127_3256237_18 - - - - 0.000000000000001188 87.0
CMS1_k127_3256237_19 Domain of unknown function DUF11 - - - 0.00008429 54.0
CMS1_k127_3256237_2 S-layer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 586.0
CMS1_k127_3256237_3 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000499 559.0
CMS1_k127_3256237_4 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 480.0
CMS1_k127_3256237_5 Involved in cell shape control K22222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 464.0
CMS1_k127_3256237_6 Aerotolerance regulator N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 391.0
CMS1_k127_3256237_7 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 323.0
CMS1_k127_3256237_8 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000008584 230.0
CMS1_k127_3256237_9 protein histidine kinase activity K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000006844 216.0
CMS1_k127_3424679_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 7.219e-319 992.0
CMS1_k127_3424679_1 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 597.0
CMS1_k127_3424679_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000001374 205.0
CMS1_k127_3424679_11 PFAM methyltransferase small K02493 - 2.1.1.297 0.000000000000000000000000000000000000000000000000001276 188.0
CMS1_k127_3424679_12 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000003542 154.0
CMS1_k127_3424679_13 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000009107 156.0
CMS1_k127_3424679_14 Protein of unknown function (DUF1699) - - - 0.000000000000000000001282 97.0
CMS1_k127_3424679_15 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000000000000000000004472 96.0
CMS1_k127_3424679_16 transcriptional K07729 - - 0.0000000000000000001824 93.0
CMS1_k127_3424679_17 - - - - 0.0000000000000001242 88.0
CMS1_k127_3424679_18 EamA-like transporter family K08978 - - 0.00001497 53.0
CMS1_k127_3424679_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 481.0
CMS1_k127_3424679_3 RNA ligase K07468 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 434.0
CMS1_k127_3424679_4 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 428.0
CMS1_k127_3424679_5 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 315.0
CMS1_k127_3424679_6 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 304.0
CMS1_k127_3424679_7 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000069 260.0
CMS1_k127_3424679_8 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004873 242.0
CMS1_k127_3424679_9 Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001606 212.0
CMS1_k127_346814_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000001459 211.0
CMS1_k127_346814_1 Radical SAM domain protein K01012 - 2.8.1.6 0.000000000000000000000000000000000000001284 154.0
CMS1_k127_346814_2 dihydromethanopterin reductase activity K00176,K06411,K12527 - 1.2.7.3,1.97.1.9 0.00000000000003759 74.0
CMS1_k127_350619_0 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000001208 201.0
CMS1_k127_350619_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000003961 107.0
CMS1_k127_350619_2 PFAM chaperonin Cpn60 TCP-1 K22447 - - 0.000000000000000006561 85.0
CMS1_k127_3615044_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.049e-203 652.0
CMS1_k127_3615044_1 UPF0210 protein K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 576.0
CMS1_k127_3615044_10 PFAM periplasmic copper-binding - - - 0.000000000000000000137 106.0
CMS1_k127_3615044_11 PFAM NHL repeat containing protein - - - 0.0000000000000000006451 90.0
CMS1_k127_3615044_12 von Willebrand factor, type A K07114 - - 0.00000000000001329 89.0
CMS1_k127_3615044_13 Periplasmic copper-binding protein (NosD) - - - 0.0000000003193 64.0
CMS1_k127_3615044_15 - - - - 0.000003911 50.0
CMS1_k127_3615044_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 493.0
CMS1_k127_3615044_3 Belongs to the peptidase S8 family K01361 - 3.4.21.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 326.0
CMS1_k127_3615044_4 Protein of unknown function (DUF531) K09725 - - 0.00000000000000000000000000000000000000000000000000000000000000000003671 239.0
CMS1_k127_3615044_5 PFAM PKD domain containing protein K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000005126 177.0
CMS1_k127_3615044_6 cellulose binding K12132 - 2.7.11.1 0.000000000000000000000000000000000000005542 170.0
CMS1_k127_3615044_7 - - - - 0.00000000000000000000000000000102 142.0
CMS1_k127_3615044_8 Parallel beta-helix - - - 0.0000000000000000000000000000155 139.0
CMS1_k127_3615044_9 Belongs to the UPF0237 family K07166 - - 0.00000000000000000001133 95.0
CMS1_k127_3636824_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 544.0
CMS1_k127_3636824_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 520.0
CMS1_k127_3636824_10 - - - - 0.000000000000002903 83.0
CMS1_k127_3636824_2 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 455.0
CMS1_k127_3636824_3 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 388.0
CMS1_k127_3636824_4 peptidyl-tyrosine sulfation K00525,K01768 - 1.17.4.1,4.6.1.1 0.00000000000000000000000000000000000000000000000000000004319 205.0
CMS1_k127_3636824_5 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000303 189.0
CMS1_k127_3636824_6 - - - - 0.00000000000000000000000000000000004925 139.0
CMS1_k127_3636824_7 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000003689 126.0
CMS1_k127_3636824_8 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000001448 116.0
CMS1_k127_3636824_9 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.00000000000000000002405 91.0
CMS1_k127_3642512_0 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 547.0
CMS1_k127_3642512_1 PFAM glutamine amidotransferase, class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 525.0
CMS1_k127_3642512_10 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000003296 172.0
CMS1_k127_3642512_11 Uncharacterized protein conserved in archaea (DUF2124) - - - 0.0000000000000000000000000000000000000003291 154.0
CMS1_k127_3642512_12 Domain of unknown function (DUF1858) - - - 0.000000000000000000002944 94.0
CMS1_k127_3642512_13 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000003243 89.0
CMS1_k127_3642512_14 sequence-specific DNA binding - - - 0.00000000001855 74.0
CMS1_k127_3642512_15 4Fe-4S dicluster domain - - - 0.0000000001279 63.0
CMS1_k127_3642512_16 - - - - 0.000000000287 67.0
CMS1_k127_3642512_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 516.0
CMS1_k127_3642512_3 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 377.0
CMS1_k127_3642512_4 Belongs to the UPF0284 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 372.0
CMS1_k127_3642512_5 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 319.0
CMS1_k127_3642512_6 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000016 290.0
CMS1_k127_3642512_7 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000000000000000000000000000005231 221.0
CMS1_k127_3642512_8 Proto-chlorophyllide reductase 57 kD subunit - - - 0.00000000000000000000000000000000000000000000000000000000121 205.0
CMS1_k127_3642512_9 - - - - 0.00000000000000000000000000000000000000000000000000004825 191.0
CMS1_k127_3648283_0 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00580 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000002704 251.0
CMS1_k127_3648283_1 NOG31153 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000000001703 234.0
CMS1_k127_3648283_2 extracellular matrix structural constituent K12287 - - 0.00000000004444 74.0
CMS1_k127_3665868_0 Male sterility protein K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 512.0
CMS1_k127_3665868_1 Polysaccharide biosynthesis protein K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 375.0
CMS1_k127_3665868_2 WxcM-like, C-terminal K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 313.0
CMS1_k127_3665868_3 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006313 287.0
CMS1_k127_3665868_4 PFAM Glycosyl transferase family 2 K12992 - - 0.000000000000000000000000000000000000000000000000000000101 205.0
CMS1_k127_3665868_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000001301 88.0
CMS1_k127_3670641_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 1.124e-253 818.0
CMS1_k127_3670641_1 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 364.0
CMS1_k127_3670641_2 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 362.0
CMS1_k127_3670641_3 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000004937 188.0
CMS1_k127_3670641_4 - - - - 0.000000000000000009432 96.0
CMS1_k127_3670641_5 - - - - 0.0000000000000001358 83.0
CMS1_k127_3670641_6 - K06864 - - 0.0000000000000007969 80.0
CMS1_k127_3670641_7 PFAM CBS domain K07182 - - 0.000000000004355 72.0
CMS1_k127_3670641_8 - - - - 0.00000000005176 72.0
CMS1_k127_3673613_0 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 354.0
CMS1_k127_3673613_1 ChaB K06197 - - 0.000000000000000000000000003378 113.0
CMS1_k127_3675193_0 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 408.0
CMS1_k127_3675193_1 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 340.0
CMS1_k127_3675193_2 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 306.0
CMS1_k127_3675193_3 Glycosyl transferase family 21 K00752,K11936 - 2.4.1.212 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 312.0
CMS1_k127_3675193_4 Protein of unknown function (DUF1648) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004481 246.0
CMS1_k127_3675193_5 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.000000000000000000000000000000000000000000000000000000008604 203.0
CMS1_k127_3675193_6 - - - - 0.00000000000000000000000000000000000000000000000000006612 192.0
CMS1_k127_3675193_7 to GB L77117 SP Q58031 PID 1591324 percent identity - - - 0.00000000000000000000000000000000000000000000001536 174.0
CMS1_k127_3675193_8 PFAM peptidase - - - 0.0000000000000000000000000000000000001038 151.0
CMS1_k127_3675249_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1333.0
CMS1_k127_3675249_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 3.557e-313 967.0
CMS1_k127_3675249_2 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 6.623e-237 742.0
CMS1_k127_3675249_3 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 509.0
CMS1_k127_3675249_4 PFAM DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 320.0
CMS1_k127_3675249_5 PhoU domain - - - 0.0000000000000000000000000000000000000000000000000000008769 205.0
CMS1_k127_3675249_6 Cytochrome c - - - 0.00000000000000000000000000000000000000000000001119 174.0
CMS1_k127_3675249_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.0000000000000000002962 91.0
CMS1_k127_3675249_9 electron transfer activity - - - 0.00000023 55.0
CMS1_k127_3688971_0 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 445.0
CMS1_k127_3688971_1 - K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 299.0
CMS1_k127_3688971_10 Uncharacterised protein family UPF0058 - - - 0.0000000000000000000000000002161 117.0
CMS1_k127_3688971_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000001303 92.0
CMS1_k127_3688971_12 Helix-turn-helix domain K07496 - - 0.0001222 46.0
CMS1_k127_3688971_13 archaeal flagellar protein C K07328,K07822 - - 0.0004426 50.0
CMS1_k127_3688971_2 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 291.0
CMS1_k127_3688971_3 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000000000003282 222.0
CMS1_k127_3688971_4 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000004935 220.0
CMS1_k127_3688971_5 COG1943 Transposase and inactivated derivatives K07491 - - 0.000000000000000000000000000000000000000000000000000000005602 203.0
CMS1_k127_3688971_6 PFAM HhH-GPD family protein K07457 - - 0.000000000000000000000000000000000000000000000000313 183.0
CMS1_k127_3688971_7 peptidase - - - 0.000000000000000000000000000000000000000000003132 166.0
CMS1_k127_3688971_8 Nitroreductase family - - - 0.000000000000000000000000000000000000000268 159.0
CMS1_k127_3688971_9 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000000001601 123.0
CMS1_k127_3689249_0 ATP-grasp domain K06913 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 301.0
CMS1_k127_3689249_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001355 279.0
CMS1_k127_3689249_2 SMART Elongator protein 3 MiaB NifB K06935 - - 0.0000000000000000000000000000000000000000000000000000000000000000002367 235.0
CMS1_k127_3689249_3 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000000000000000000000000002961 227.0
CMS1_k127_3689249_4 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.00000000000000000000000000000000000000000000000000000001371 202.0
CMS1_k127_3689249_5 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.00000000000000000000000000000000000000000000004694 175.0
CMS1_k127_3689249_6 Radical SAM domain protein K09711 - - 0.000000000000000000000000000000000002676 143.0
CMS1_k127_3689249_7 heme binding K21472 - - 0.0000000000000000000000000006323 124.0
CMS1_k127_3689249_8 Protein of unknown function (DUF2551) - - - 0.0000000000000000000000004881 108.0
CMS1_k127_3742001_0 SMART Elongator protein 3 MiaB NifB K22226 - - 2.378e-238 739.0
CMS1_k127_3742001_1 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 601.0
CMS1_k127_3742001_10 MMPL family K07003 - - 0.00000000000000000000000000000000009574 147.0
CMS1_k127_3742001_11 response to oxidative stress K04063 - - 0.000000000000000000000006108 106.0
CMS1_k127_3742001_2 CcmB protein K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008898 260.0
CMS1_k127_3742001_3 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000002451 245.0
CMS1_k127_3742001_4 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.000000000000000000000000000000000000000000000000000000000000000000009296 238.0
CMS1_k127_3742001_5 Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000004043 229.0
CMS1_k127_3742001_6 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000001126 195.0
CMS1_k127_3742001_7 Domain of unknown function (DUF814) - - - 0.0000000000000000000000000000000000000000000000001351 180.0
CMS1_k127_3742001_8 COG1361 S-layer domain - - - 0.0000000000000000000000000000000000000003171 164.0
CMS1_k127_3742001_9 transcriptional - - - 0.0000000000000000000000000000000000001449 153.0
CMS1_k127_3750647_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 5.286e-233 737.0
CMS1_k127_3750647_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 466.0
CMS1_k127_3750647_10 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001024 264.0
CMS1_k127_3750647_11 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000000000005095 238.0
CMS1_k127_3750647_12 Putative small multi-drug export protein - - - 0.0000000000000000000000000000000000000000000000000000001148 199.0
CMS1_k127_3750647_13 ArsR transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000001073 194.0
CMS1_k127_3750647_14 Belongs to the UPF0179 family K09730 - - 0.000000000000000000000000000000000000000004447 158.0
CMS1_k127_3750647_15 Stage II sporulation protein M K06384 - - 0.0000000000000000000000000000000000003388 147.0
CMS1_k127_3750647_16 Stage II sporulation protein M K06384 - - 0.0000000000000000000000000000000003951 138.0
CMS1_k127_3750647_17 Protein of unknown function (DUF433) - - - 0.00000000000000000000006478 101.0
CMS1_k127_3750647_18 - - - - 0.0000000000000000000002879 98.0
CMS1_k127_3750647_19 - - - - 0.0003852 45.0
CMS1_k127_3750647_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 445.0
CMS1_k127_3750647_3 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 364.0
CMS1_k127_3750647_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 361.0
CMS1_k127_3750647_5 SMART regulatory protein, Crp K07730 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006997 343.0
CMS1_k127_3750647_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006028 346.0
CMS1_k127_3750647_7 PFAM metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 336.0
CMS1_k127_3750647_8 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 316.0
CMS1_k127_3750647_9 Membrane protein of unknown function DUF63 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002771 276.0
CMS1_k127_3769976_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.119e-229 719.0
CMS1_k127_3769976_1 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 627.0
CMS1_k127_3769976_10 - - - - 0.000000000000000000000000001158 117.0
CMS1_k127_3769976_11 Transcription factor Pcc1 K09741 - - 0.00000000006164 65.0
CMS1_k127_3769976_12 n-acetylmuramoyl-L-alanine amidase K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.000009739 59.0
CMS1_k127_3769976_13 nuclease activity K06218 - - 0.00001512 48.0
CMS1_k127_3769976_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 393.0
CMS1_k127_3769976_3 DHH family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 392.0
CMS1_k127_3769976_4 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 333.0
CMS1_k127_3769976_5 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000312 270.0
CMS1_k127_3769976_6 Glycosyltransferase like family 2 K13002 - - 0.00000000000000000000000000000000000000000000000000000000009314 214.0
CMS1_k127_3769976_7 parallel beta-helix repeat - - - 0.0000000000000000000000000000000001856 151.0
CMS1_k127_3769976_8 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000000000000000000000003709 128.0
CMS1_k127_3769976_9 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000001558 122.0
CMS1_k127_3819086_0 PFAM Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000005411 186.0
CMS1_k127_3823726_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1086.0
CMS1_k127_3823726_1 Heat shock 70 kDa protein K04043 - - 1.268e-269 841.0
CMS1_k127_3823726_10 AMP-binding enzyme C-terminal domain K01895 GO:0003674,GO:0003824,GO:0003996,GO:0004321,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0015645,GO:0016053,GO:0016405,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0016874,GO:0016877,GO:0016878,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 455.0
CMS1_k127_3823726_11 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 346.0
CMS1_k127_3823726_12 ABC transporter K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 332.0
CMS1_k127_3823726_13 Thermophilic metalloprotease (M29) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009155 296.0
CMS1_k127_3823726_14 -transporter K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001364 272.0
CMS1_k127_3823726_15 Belongs to the bacterial solute-binding protein 3 family K02030,K02424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002944 269.0
CMS1_k127_3823726_16 membrane-associated protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002542 263.0
CMS1_k127_3823726_17 TIGRFAM archaeoflavoprotein AfpA - - - 0.0000000000000000000000000000000000000000000000000000000000000331 220.0
CMS1_k127_3823726_18 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000326 220.0
CMS1_k127_3823726_19 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000000000005579 209.0
CMS1_k127_3823726_2 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 1.355e-239 755.0
CMS1_k127_3823726_20 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000008194 214.0
CMS1_k127_3823726_21 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000002805 188.0
CMS1_k127_3823726_22 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000003134 179.0
CMS1_k127_3823726_23 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000001321 170.0
CMS1_k127_3823726_24 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000003203 158.0
CMS1_k127_3823726_25 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000001222 161.0
CMS1_k127_3823726_26 metallopeptidase activity K06974 - - 0.0000000000000000000000000000000000002013 147.0
CMS1_k127_3823726_27 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000001999 118.0
CMS1_k127_3823726_28 - - - - 0.000000000000000000255 90.0
CMS1_k127_3823726_29 methyltransferase - - - 0.000000000000008709 81.0
CMS1_k127_3823726_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.268e-235 736.0
CMS1_k127_3823726_30 - - - - 0.0000000000001321 70.0
CMS1_k127_3823726_31 - - - - 0.00000000001007 72.0
CMS1_k127_3823726_32 - - - - 0.000000000189 70.0
CMS1_k127_3823726_33 Radical SAM superfamily K04069 - 1.97.1.4 0.000000004935 59.0
CMS1_k127_3823726_34 Arrestin (or S-antigen), C-terminal domain - - - 0.000001571 55.0
CMS1_k127_3823726_35 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.000003781 49.0
CMS1_k127_3823726_36 PFAM transposase IS200-family protein K07491 - - 0.0001147 45.0
CMS1_k127_3823726_37 Putative transposase DNA-binding domain K07496 - - 0.0001351 46.0
CMS1_k127_3823726_38 Arrestin (or S-antigen), C-terminal domain - - - 0.0001392 50.0
CMS1_k127_3823726_39 - - - - 0.0001816 53.0
CMS1_k127_3823726_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.485e-230 717.0
CMS1_k127_3823726_5 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 9.681e-220 691.0
CMS1_k127_3823726_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.049e-214 672.0
CMS1_k127_3823726_7 PFAM chaperonin Cpn60 TCP-1 K22447 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 599.0
CMS1_k127_3823726_8 DNA polymerase K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 565.0
CMS1_k127_3823726_9 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 529.0
CMS1_k127_3836214_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 1.84e-199 624.0
CMS1_k127_3836214_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 401.0
CMS1_k127_3836214_2 MviN-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000012 252.0
CMS1_k127_3836214_3 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000007206 89.0
CMS1_k127_3856822_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 476.0
CMS1_k127_3856822_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008423 389.0
CMS1_k127_3856822_2 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000196 145.0
CMS1_k127_3856822_3 - - - - 0.0000009194 55.0
CMS1_k127_3856822_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.0001924 52.0
CMS1_k127_3856853_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000003938 107.0
CMS1_k127_3856853_1 repeat-containing protein - - - 0.000000000000004581 81.0
CMS1_k127_3868536_0 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 507.0
CMS1_k127_3868536_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 422.0
CMS1_k127_3868536_2 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 359.0
CMS1_k127_3868536_3 Domain of unknown function DUF128 K21640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009006 308.0
CMS1_k127_3868536_4 Protein of unknown function (DUF98) - - - 0.00000000000000000000000000000000000000000000000000009478 190.0
CMS1_k127_3868536_5 - - - - 0.000000000000000000000000000000000000000001081 169.0
CMS1_k127_3868536_6 - - - - 0.000000000000000000000000000002578 122.0
CMS1_k127_3868536_7 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000000007431 108.0
CMS1_k127_3868536_8 Uncharacterized metal-binding protein (DUF2227) - - - 0.000000000000000009234 88.0
CMS1_k127_3868536_9 COG1943 Transposase and inactivated derivatives K07491 - - 0.0009645 43.0
CMS1_k127_3888952_0 Amidase K01426,K19176 - 3.5.1.4,3.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 517.0
CMS1_k127_3888952_1 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004869 288.0
CMS1_k127_3888952_2 - - - - 0.0000000000000635 79.0
CMS1_k127_3888952_3 Transposase IS200 like K07491 - - 0.0001091 49.0
CMS1_k127_3947378_0 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006398 252.0
CMS1_k127_3947378_1 - - - - 0.0000000000000001646 88.0
CMS1_k127_3979470_0 Multicopper oxidase - - - 0.0 1770.0
CMS1_k127_3979470_1 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 420.0
CMS1_k127_3979470_10 - - - - 0.00000000000001659 74.0
CMS1_k127_3979470_11 cell adhesion involved in biofilm formation - - - 0.000000003083 70.0
CMS1_k127_3979470_12 - - - - 0.00000002173 66.0
CMS1_k127_3979470_13 transcriptional - - - 0.000001503 55.0
CMS1_k127_3979470_14 - - - - 0.000004265 57.0
CMS1_k127_3979470_2 Integral membrane protein TerC family K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 361.0
CMS1_k127_3979470_3 Flavodoxin-like fold K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 331.0
CMS1_k127_3979470_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 305.0
CMS1_k127_3979470_5 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000001254 197.0
CMS1_k127_3979470_6 metallopeptidase activity K20276 - - 0.0000000000000000000000000000000000000000000000005524 197.0
CMS1_k127_3979470_7 Cytochrome D1 heme domain - - - 0.00000000000000000000000000000000000000000000615 184.0
CMS1_k127_3979470_8 - - - - 0.000000000000000000000000114 108.0
CMS1_k127_3979470_9 PFAM Beta propeller domain K14475 - - 0.00000000000000000005474 92.0
CMS1_k127_3981883_0 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 457.0
CMS1_k127_3981883_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 404.0
CMS1_k127_3981883_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 328.0
CMS1_k127_3981883_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000001092 151.0
CMS1_k127_3981883_4 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.0000000000000000000000005139 117.0
CMS1_k127_4007763_0 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 561.0
CMS1_k127_4007763_1 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 389.0
CMS1_k127_4007763_2 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 371.0
CMS1_k127_4007763_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007952 275.0
CMS1_k127_4007763_4 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000000881 158.0
CMS1_k127_4007763_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000003406 113.0
CMS1_k127_4007763_6 Family of unknown function (DUF5371) - - - 0.0000000000000000005476 87.0
CMS1_k127_4007763_7 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000007543 83.0
CMS1_k127_4030517_0 Belongs to the glutamate synthase family - - - 1.064e-231 725.0
CMS1_k127_4030517_1 PFAM Radical SAM domain protein K06871 - - 1.499e-194 612.0
CMS1_k127_4030517_10 Methanogenesis marker protein 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 343.0
CMS1_k127_4030517_11 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 314.0
CMS1_k127_4030517_12 PFAM ATP-NAD AcoX kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 310.0
CMS1_k127_4030517_13 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 308.0
CMS1_k127_4030517_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 290.0
CMS1_k127_4030517_15 COG0095 Lipoate-protein ligase A K03800 GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0051604,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901681 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000001067 269.0
CMS1_k127_4030517_16 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000002869 263.0
CMS1_k127_4030517_17 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000008803 262.0
CMS1_k127_4030517_18 membrane transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001816 253.0
CMS1_k127_4030517_19 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000002198 244.0
CMS1_k127_4030517_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 582.0
CMS1_k127_4030517_20 STAS domain K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000001995 239.0
CMS1_k127_4030517_21 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000002092 220.0
CMS1_k127_4030517_22 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000006616 229.0
CMS1_k127_4030517_23 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000000000000000000000000000000000000000000000000000000007611 213.0
CMS1_k127_4030517_24 dna ligase K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000001234 184.0
CMS1_k127_4030517_25 - - - - 0.000000000000000000000000000000000000000000002984 173.0
CMS1_k127_4030517_26 Histidine kinase-like ATPase domain K17752 - 2.7.11.1 0.0000000000000000000000000000000000000324 147.0
CMS1_k127_4030517_27 Protein of unknown function (DUF1284) K09706 - - 0.0000000000000000000000000000002255 126.0
CMS1_k127_4030517_28 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000002466 143.0
CMS1_k127_4030517_29 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 0.0000000000000000000000000003484 114.0
CMS1_k127_4030517_3 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP-binding K00158 - 1.2.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 528.0
CMS1_k127_4030517_30 transporter antisigma-factor antagonist STAS K17762 - - 0.000000000000000000000000002451 115.0
CMS1_k127_4030517_31 Protein of unknown function (DUF2769) - - - 0.000000000000000000000000003894 111.0
CMS1_k127_4030517_32 phosphoserine phosphatase activity K04757,K05518,K07315,K17752 - 2.7.11.1,3.1.3.3 0.00000000000000000000000004342 115.0
CMS1_k127_4030517_33 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000006792 97.0
CMS1_k127_4030517_34 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.00000000000000000005206 93.0
CMS1_k127_4030517_35 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000003462 72.0
CMS1_k127_4030517_36 - - - - 0.0000000007024 63.0
CMS1_k127_4030517_37 - - - - 0.00000009259 56.0
CMS1_k127_4030517_38 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00006949 48.0
CMS1_k127_4030517_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 449.0
CMS1_k127_4030517_5 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 399.0
CMS1_k127_4030517_6 Beta-eliminating lyase K01667 - 4.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 388.0
CMS1_k127_4030517_7 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 376.0
CMS1_k127_4030517_8 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 350.0
CMS1_k127_4030517_9 PFAM Patatin K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 348.0
CMS1_k127_4047385_0 PFAM ferredoxin-dependent glutamate synthase - - - 3.768e-292 902.0
CMS1_k127_4047385_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 5.295e-207 652.0
CMS1_k127_4047385_10 UbiE COQ5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 338.0
CMS1_k127_4047385_11 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 332.0
CMS1_k127_4047385_12 Arsenite-activated ATPase (ArsA) K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 322.0
CMS1_k127_4047385_13 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 303.0
CMS1_k127_4047385_14 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000002874 206.0
CMS1_k127_4047385_15 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000003558 209.0
CMS1_k127_4047385_16 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000000000639 196.0
CMS1_k127_4047385_17 TspO/MBR family K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000639 196.0
CMS1_k127_4047385_19 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000002779 196.0
CMS1_k127_4047385_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 617.0
CMS1_k127_4047385_20 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000001214 179.0
CMS1_k127_4047385_21 - - - - 0.00000000000000000000000000000000000000000000009338 171.0
CMS1_k127_4047385_22 Uncharacterized protein conserved in archaea (DUF2119) - - - 0.0000000000000000000000000000000000000000000009711 172.0
CMS1_k127_4047385_23 PFAM Glycosyltransferase 28 domain - - - 0.000000000000000000000000000000003195 143.0
CMS1_k127_4047385_24 - - - - 0.00000000000000000000000000002342 119.0
CMS1_k127_4047385_25 - - - - 0.0000000000000000000000000143 111.0
CMS1_k127_4047385_26 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000006679 118.0
CMS1_k127_4047385_27 Transcriptional regulator, TrmB - - - 0.00000000000000000000001114 104.0
CMS1_k127_4047385_28 - K00960 - 2.7.7.6 0.00000000000000000000003739 100.0
CMS1_k127_4047385_29 Cytochrome b5-like Heme/Steroid binding domain - - - 0.0000000000000000000008514 98.0
CMS1_k127_4047385_3 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 441.0
CMS1_k127_4047385_30 - - - - 0.0000000000000000003355 101.0
CMS1_k127_4047385_31 TRAM domain - - - 0.0000000000000000008266 88.0
CMS1_k127_4047385_32 - - - - 0.00000000000000001301 85.0
CMS1_k127_4047385_33 positive regulation of type IV pilus biogenesis K07343 - - 0.0000000000000001417 84.0
CMS1_k127_4047385_34 Glycosyltransferase family 28 C-terminal domain - - - 0.000000002826 63.0
CMS1_k127_4047385_35 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000008634 58.0
CMS1_k127_4047385_4 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 422.0
CMS1_k127_4047385_5 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 393.0
CMS1_k127_4047385_6 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 395.0
CMS1_k127_4047385_7 PFAM zinc iron permease K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 387.0
CMS1_k127_4047385_8 carbon starvation protein CstA K06200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 368.0
CMS1_k127_4047385_9 COG2406 Protein distantly related to bacterial ferritins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 340.0
CMS1_k127_4049700_0 COG0464 ATPases of the AAA class K13525 - - 0.0 1032.0
CMS1_k127_4049700_1 KH, type 1, domain K07041 - - 0.0 1009.0
CMS1_k127_4049700_10 Putative ATP-dependant zinc protease - - - 0.0000000000000000000000000000000000000000000004584 173.0
CMS1_k127_4049700_11 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000001742 173.0
CMS1_k127_4049700_12 Domain of unknown function (DUF296) K06934 - - 0.000000000000000000000000000000000000000000114 164.0
CMS1_k127_4049700_13 Domain of unknown function (DUF4870) - - - 0.0000000000000000000000000000000000000000001241 161.0
CMS1_k127_4049700_14 Phage integrase family - - - 0.00000000000000000000000000000000000002438 151.0
CMS1_k127_4049700_15 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000001034 145.0
CMS1_k127_4049700_16 metallopeptidase activity K01193,K01212,K02809,K02810,K03332,K18775,K19668 GO:0003674,GO:0003824,GO:0004553,GO:0004564,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005984,GO:0005985,GO:0005987,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016787,GO:0016798,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044424,GO:0044464,GO:0046352,GO:0071704,GO:1901575 2.7.1.211,3.2.1.26,3.2.1.64,3.2.1.65,3.2.1.80,3.2.1.91 0.00000000000000000000000000000008485 135.0
CMS1_k127_4049700_17 GYD domain - - - 0.0000000000000000000000000000002922 124.0
CMS1_k127_4049700_18 Membrane protein of unknown function DUF63 - - - 0.0000000000000000000000000000003637 133.0
CMS1_k127_4049700_19 Double zinc ribbon - - - 0.000000000000000000000000000191 121.0
CMS1_k127_4049700_2 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 3.818e-210 668.0
CMS1_k127_4049700_20 cyclic nucleotide binding K00384,K01420 - 1.8.1.9 0.00000000000000000000000004045 108.0
CMS1_k127_4049700_22 Polymer-forming cytoskeletal - - - 0.00000000000000000000002356 113.0
CMS1_k127_4049700_23 PFAM PRC-barrel domain - - - 0.000000000000000000002627 95.0
CMS1_k127_4049700_24 PFAM YHS domain - - - 0.0000000000000000001393 89.0
CMS1_k127_4049700_25 - - - - 0.0000000000000008895 83.0
CMS1_k127_4049700_26 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000006027 73.0
CMS1_k127_4049700_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 558.0
CMS1_k127_4049700_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 517.0
CMS1_k127_4049700_5 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 362.0
CMS1_k127_4049700_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 336.0
CMS1_k127_4049700_7 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 295.0
CMS1_k127_4049700_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000002441 207.0
CMS1_k127_4049700_9 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000002473 182.0
CMS1_k127_4108974_0 PFAM D-aminoacylase, C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 409.0
CMS1_k127_4108974_1 Amidohydrolase family - - - 0.0000000000000000000000000000002529 128.0
CMS1_k127_4197176_0 PHP C-terminal domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 496.0
CMS1_k127_4197176_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 394.0
CMS1_k127_4197176_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 350.0
CMS1_k127_4197176_3 Nitroreductase family - - - 0.000000000000000000000000000004207 125.0
CMS1_k127_4197176_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000001261 115.0
CMS1_k127_4197176_5 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.0000000000000000008266 88.0
CMS1_k127_4197176_6 structural constituent of ribosome K02962 - - 0.0000000000001255 72.0
CMS1_k127_4221974_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1261.0
CMS1_k127_4221974_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 520.0
CMS1_k127_4221974_2 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 425.0
CMS1_k127_4221974_3 Pfam:DUF650 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 366.0
CMS1_k127_4221974_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 331.0
CMS1_k127_4221974_5 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003857 271.0
CMS1_k127_4221974_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000131 146.0
CMS1_k127_4221974_7 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000001868 130.0
CMS1_k127_4221974_8 Protein of unknown function (DUF3795) - - - 0.00000004857 57.0
CMS1_k127_4280322_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 1.221e-256 800.0
CMS1_k127_4280322_1 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 601.0
CMS1_k127_4280322_10 Zinc dependent phospholipase C - - - 0.0009801 50.0
CMS1_k127_4280322_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 595.0
CMS1_k127_4280322_3 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 573.0
CMS1_k127_4280322_4 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 400.0
CMS1_k127_4280322_5 Helix-turn-helix domain protein K07731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 292.0
CMS1_k127_4280322_6 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000203 288.0
CMS1_k127_4280322_7 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000003518 234.0
CMS1_k127_4280322_8 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000000694 190.0
CMS1_k127_4280322_9 HWE histidine kinase - - - 0.000000000000002337 76.0
CMS1_k127_4280392_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 1.17e-198 627.0
CMS1_k127_4280392_1 Pfam:DUF258 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 293.0
CMS1_k127_4280392_2 Thi4 family - - - 0.000000000000000000000000000000000000000888 166.0
CMS1_k127_4493845_0 PFAM amine oxidase - - - 1.762e-194 614.0
CMS1_k127_4493845_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 496.0
CMS1_k127_4493845_10 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000004165 220.0
CMS1_k127_4493845_11 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000007104 185.0
CMS1_k127_4493845_12 FMN binding - - - 0.00000000000000000000000000000000000001564 146.0
CMS1_k127_4493845_13 transferase activity, transferring glycosyl groups K13678 GO:0003674,GO:0003824,GO:0006629,GO:0006643,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016757,GO:0016758,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901576 - 0.00000000000000000000000000000000003024 147.0
CMS1_k127_4493845_14 COG1361 S-layer domain - - - 0.0000000000000000000000000000006553 136.0
CMS1_k127_4493845_15 - - - - 0.0000000000000000000006868 107.0
CMS1_k127_4493845_16 membrane-associated protein domain - - - 0.00000000000439 73.0
CMS1_k127_4493845_17 Belongs to the UPF0758 family K03630 - - 0.00000003595 56.0
CMS1_k127_4493845_18 smart pdz dhr glgf - - - 0.00000228 51.0
CMS1_k127_4493845_2 SMART Elongator protein 3 MiaB NifB K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 398.0
CMS1_k127_4493845_3 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 356.0
CMS1_k127_4493845_4 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 347.0
CMS1_k127_4493845_5 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 348.0
CMS1_k127_4493845_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 325.0
CMS1_k127_4493845_7 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003313 268.0
CMS1_k127_4493845_8 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000005482 241.0
CMS1_k127_4493845_9 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000003854 224.0
CMS1_k127_4552050_0 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001042 247.0
CMS1_k127_4552050_1 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000000001289 196.0
CMS1_k127_4552050_2 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) K19091 GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0034641,GO:0043170,GO:0043570,GO:0043571,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000007428 169.0
CMS1_k127_4552050_3 - - - - 0.00000000000000000000000000007346 132.0
CMS1_k127_4552050_4 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) K19091 GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0034641,GO:0043170,GO:0043570,GO:0043571,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000006428 108.0
CMS1_k127_4552050_5 polysaccharide deacetylase - - - 0.000004332 56.0
CMS1_k127_4552050_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.000005206 49.0
CMS1_k127_4564795_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1259.0
CMS1_k127_4564795_1 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 581.0
CMS1_k127_4564795_10 Integral membrane sensor signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000002976 220.0
CMS1_k127_4564795_11 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000001164 169.0
CMS1_k127_4564795_12 cheY-homologous receiver domain K07668 - - 0.000000000000000000000000000000000000000002177 159.0
CMS1_k127_4564795_13 Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000000006687 145.0
CMS1_k127_4564795_14 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000001493 104.0
CMS1_k127_4564795_15 Glycosyl transferase family group 2 K00752 - 2.4.1.212 0.00003153 47.0
CMS1_k127_4564795_2 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 424.0
CMS1_k127_4564795_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 340.0
CMS1_k127_4564795_4 PFAM Glycosyl transferase family 2 K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 325.0
CMS1_k127_4564795_5 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002787 258.0
CMS1_k127_4564795_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001172 261.0
CMS1_k127_4564795_7 Phosphonate ABC transporter, periplasmic K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003509 259.0
CMS1_k127_4564795_8 Pfam:KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006689 264.0
CMS1_k127_4564795_9 Uncharacterized protein conserved in archaea (DUF2150) - - - 0.0000000000000000000000000000000000000000000000000000000000000008455 225.0
CMS1_k127_4567518_0 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 436.0
CMS1_k127_4567518_1 PFAM DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001301 256.0
CMS1_k127_4568988_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 462.0
CMS1_k127_4568988_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 453.0
CMS1_k127_4568988_10 - - - - 0.00000000000000000000000000000000000000000000008059 171.0
CMS1_k127_4568988_11 Phage integrase family - - - 0.000000000000000000000000000000000000000000004153 179.0
CMS1_k127_4568988_12 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000001058 171.0
CMS1_k127_4568988_13 Domain of unknown function DUF123 - - - 0.00000000000000000000000000001964 122.0
CMS1_k127_4568988_14 RNA binding K07581 - - 0.0000000000000000000000000001823 119.0
CMS1_k127_4568988_15 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000003394 100.0
CMS1_k127_4568988_16 transcriptional - - - 0.0000000000003807 81.0
CMS1_k127_4568988_17 - - - - 0.00000000002121 70.0
CMS1_k127_4568988_18 - - - - 0.000003249 55.0
CMS1_k127_4568988_19 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.0002106 53.0
CMS1_k127_4568988_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 399.0
CMS1_k127_4568988_3 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 348.0
CMS1_k127_4568988_4 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000667 280.0
CMS1_k127_4568988_5 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002584 278.0
CMS1_k127_4568988_6 by modhmm K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000004522 271.0
CMS1_k127_4568988_7 S-layer protein - - - 0.0000000000000000000000000000000000000000000000000000000000000008308 242.0
CMS1_k127_4568988_8 amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000008914 194.0
CMS1_k127_4568988_9 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000005293 190.0
CMS1_k127_4571888_0 Pfam:KaiC K08482 - - 4.213e-239 751.0
CMS1_k127_4571888_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 508.0
CMS1_k127_4571888_10 SMART Elongator protein 3 MiaB NifB K06935,K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000516 167.0
CMS1_k127_4571888_11 cheY-homologous receiver domain K07658 - - 0.0000000000000000000000000000000000001377 144.0
CMS1_k127_4571888_12 KaiB K08481 - - 0.000000000000000000000000000000000003077 139.0
CMS1_k127_4571888_13 Transposase IS200 like K07491 - - 0.00004861 51.0
CMS1_k127_4571888_2 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 361.0
CMS1_k127_4571888_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 347.0
CMS1_k127_4571888_4 PFAM HhH-GPD family protein K07457 - - 0.000000000000000000000000000000000000000000000000000000000000001526 223.0
CMS1_k127_4571888_5 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000007736 214.0
CMS1_k127_4571888_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000003295 205.0
CMS1_k127_4571888_7 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000001985 194.0
CMS1_k127_4571888_8 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000000000000000000000000000000000000001247 190.0
CMS1_k127_4571888_9 KaiB K08481 - - 0.000000000000000000000000000000000000000000002696 165.0
CMS1_k127_4572639_0 DEAD DEAH box helicase domain protein K10896 - - 1.468e-277 871.0
CMS1_k127_4572639_1 PFAM 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 445.0
CMS1_k127_4572639_2 - - - - 0.0000005483 56.0
CMS1_k127_4572639_3 blue (type 1) copper K00368 - 1.7.2.1 0.00000599 56.0
CMS1_k127_4624661_0 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000001717 194.0
CMS1_k127_4624661_1 Erf family - - - 0.0000000000000000000000000000000000000000000004519 172.0
CMS1_k127_4647597_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.383e-213 668.0
CMS1_k127_4647597_1 Mn2 dependent serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 468.0
CMS1_k127_4647597_10 Belongs to the UPF0235 family K09131 - - 0.0000000000000000001287 91.0
CMS1_k127_4647597_11 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000003141 78.0
CMS1_k127_4647597_12 Copper binding proteins, plastocyanin/azurin family - - - 0.00000005233 59.0
CMS1_k127_4647597_2 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000002012 235.0
CMS1_k127_4647597_3 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000006079 226.0
CMS1_k127_4647597_4 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000000000004326 169.0
CMS1_k127_4647597_5 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000458 168.0
CMS1_k127_4647597_6 DNA-binding transcription factor activity K02444,K03655 - 3.6.4.12 0.00000000000000000000000000000000736 138.0
CMS1_k127_4647597_7 Protein of unknown function (DUF1670) - - - 0.0000000000000000000000000000009762 132.0
CMS1_k127_4647597_8 metal ion binding - - - 0.00000000000000000000000000001524 124.0
CMS1_k127_4647597_9 - - - - 0.0000000000000000000002633 97.0
CMS1_k127_4650032_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 313.0
CMS1_k127_4650032_1 ABC-type transport auxiliary lipoprotein component K09857 - - 0.0000000000000000000000000000000000000000007724 164.0
CMS1_k127_4650032_2 MlaD protein K06192 - - 0.00000000009672 64.0
CMS1_k127_4650059_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 600.0
CMS1_k127_4650059_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 587.0
CMS1_k127_4650059_2 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 463.0
CMS1_k127_4650059_3 COG1943 Transposase and inactivated derivatives K07491 - - 0.000000000000000000000009406 106.0
CMS1_k127_4663991_0 PFAM chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007957 302.0
CMS1_k127_4663991_1 chemotaxis protein K03406 - - 0.000000000005112 74.0
CMS1_k127_4663991_2 PFAM CheW domain protein K03408 - - 0.0000003975 53.0
CMS1_k127_4665914_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.463e-266 834.0
CMS1_k127_4665914_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 441.0
CMS1_k127_4665914_2 pfam nmd3 K07562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 312.0
CMS1_k127_4667701_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 493.0
CMS1_k127_4667701_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000001752 237.0
CMS1_k127_4667701_2 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000006904 224.0
CMS1_k127_4667701_3 transcription termination protein NusA K02600 - - 0.00000000000000000000000000000000000000000000000000004605 190.0
CMS1_k127_4667701_4 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.000000000000000001705 88.0
CMS1_k127_4667701_5 Transposase IS200 like K07491 - - 0.0007619 44.0
CMS1_k127_4684754_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 492.0
CMS1_k127_4684754_1 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 382.0
CMS1_k127_4684754_2 Protein of unknown function (DUF4256) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 303.0
CMS1_k127_4684754_3 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004599 275.0
CMS1_k127_4684754_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000000000000002796 185.0
CMS1_k127_4684754_5 dihydrofolate reductase activity - - - 0.000000000000000000000000000000000000000000000000417 181.0
CMS1_k127_4684754_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000001505 144.0
CMS1_k127_4684754_7 Cyclase dehydrase - - - 0.000000000000000000000000000003089 124.0
CMS1_k127_4684754_8 PFAM Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000003739 121.0
CMS1_k127_4684754_9 - - - - 0.0000000000008787 74.0
CMS1_k127_4686857_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1596.0
CMS1_k127_4686857_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 368.0
CMS1_k127_4689116_0 GDP dissociation inhibitor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004475 309.0
CMS1_k127_4689116_1 methyltransferase K18896,K18897 GO:0001505,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006544,GO:0006575,GO:0006577,GO:0006578,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0009058,GO:0009069,GO:0009987,GO:0016740,GO:0016741,GO:0017144,GO:0017174,GO:0019286,GO:0019752,GO:0031455,GO:0031456,GO:0032259,GO:0034641,GO:0042133,GO:0042398,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0052730,GO:0065007,GO:0065008,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.1.1.156,2.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004083 277.0
CMS1_k127_4689116_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000005087 183.0
CMS1_k127_4689116_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000000000000000000000000000000000000001451 159.0
CMS1_k127_4689116_4 Trm112p-like protein - - - 0.000000000000000000000001377 103.0
CMS1_k127_4689116_6 Possibly the antitoxin component of a - - - 0.000000000004755 69.0
CMS1_k127_4709542_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 347.0
CMS1_k127_4709542_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 325.0
CMS1_k127_4709542_2 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.0000000000000000000000000000000000000001668 161.0
CMS1_k127_4709542_3 - - - - 0.000000000000000000000000000000006743 144.0
CMS1_k127_4709542_4 - - - - 0.00000000000000000000000000000002199 143.0
CMS1_k127_4709542_5 - - - - 0.00000000000000000000000000000005173 141.0
CMS1_k127_4709542_6 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000006914 133.0
CMS1_k127_4709542_7 PFAM Cytochrome c, bacterial - - - 0.000000000003726 76.0
CMS1_k127_4713499_0 DNA photolyase K01669 - 4.1.99.3 1.12e-199 630.0
CMS1_k127_4713499_1 epimerase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000001446 181.0
CMS1_k127_4713499_2 TspO/MBR family - - - 0.0000001097 53.0
CMS1_k127_4713499_3 PFAM TspO MBR family protein K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.0000001214 55.0
CMS1_k127_4714556_0 signal transduction protein with CBS domains K07744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 374.0
CMS1_k127_4714556_1 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 340.0
CMS1_k127_4721344_0 - - - - 0.000000000000000000002655 101.0
CMS1_k127_4721344_1 ATPase family associated with various cellular activities (AAA) - - - 0.0000000001229 67.0
CMS1_k127_4721344_2 Pfam:Arch_ATPase - - - 0.0000000008219 68.0
CMS1_k127_4721344_3 Belongs to the ompA family - - - 0.00000002662 59.0
CMS1_k127_4733562_0 - - - - 0.0000112 53.0
CMS1_k127_4737743_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 4.219e-219 687.0
CMS1_k127_4737743_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.36e-216 682.0
CMS1_k127_4737743_10 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.000000000000000000000000000000000000000001155 159.0
CMS1_k127_4737743_11 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000002465 161.0
CMS1_k127_4737743_12 Belongs to the GbsR family - - - 0.0000000000000000000000000000000000000008112 153.0
CMS1_k127_4737743_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000001403 134.0
CMS1_k127_4737743_14 Eco57I restriction-modification methylase - - - 0.000000000000000000000000000000004051 138.0
CMS1_k127_4737743_15 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0000000000000000000000000000005324 124.0
CMS1_k127_4737743_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000003997 103.0
CMS1_k127_4737743_17 N-ATPase, AtpR subunit - - - 0.00000000000000000682 87.0
CMS1_k127_4737743_18 - - - - 0.00000000000007921 83.0
CMS1_k127_4737743_19 - - - - 0.0000000000005984 72.0
CMS1_k127_4737743_2 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 475.0
CMS1_k127_4737743_20 toxin, RelE StbE family K06218 - - 0.0000000113 59.0
CMS1_k127_4737743_3 PFAM sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 460.0
CMS1_k127_4737743_4 Kef-type K transport systems, membrane components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 434.0
CMS1_k127_4737743_5 ATP synthase K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 328.0
CMS1_k127_4737743_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 292.0
CMS1_k127_4737743_7 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 289.0
CMS1_k127_4737743_8 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000413 212.0
CMS1_k127_4737743_9 RuvA, C-terminal domain K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000003952 166.0
CMS1_k127_4742335_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 602.0
CMS1_k127_4742335_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 335.0
CMS1_k127_4742335_2 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000003627 240.0
CMS1_k127_4742335_3 Methyltransferase domain - - - 0.000000000000000000000000000000000006638 140.0
CMS1_k127_4742335_4 Transposase IS200 like - - - 0.00000000000000003702 84.0
CMS1_k127_4742335_6 - - - - 0.00003916 48.0
CMS1_k127_4743917_0 KAP family P-loop domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 403.0
CMS1_k127_4743917_1 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007024 251.0
CMS1_k127_4743917_2 PFAM response regulator receiver - - - 0.00000000000000000000000000000001452 131.0
CMS1_k127_4743917_3 cheY-homologous receiver domain - - - 0.0000000000000000000000002801 113.0
CMS1_k127_4743917_4 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively - - - 0.000000000000000552 93.0
CMS1_k127_4743917_5 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000002624 70.0
CMS1_k127_4751894_0 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002696 251.0
CMS1_k127_4751894_1 - - - - 0.00000000000000000000000000000000000000000000003291 179.0
CMS1_k127_4751894_2 Redoxin - - - 0.00000000000000000000001509 113.0
CMS1_k127_4751894_3 DEAD/H associated K03724 - - 0.0008741 42.0
CMS1_k127_4774435_0 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 339.0
CMS1_k127_4774435_1 HNH endonuclease K07454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001461 278.0
CMS1_k127_4774435_2 Methyltransferase domain K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000009516 241.0
CMS1_k127_4774435_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.0000000000000000000000000000006309 125.0
CMS1_k127_4844827_0 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 591.0
CMS1_k127_4844827_1 Uncharacterized protein family (UPF0051) K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 334.0
CMS1_k127_4844827_2 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003931 268.0
CMS1_k127_4844827_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006305 258.0
CMS1_k127_4844827_4 regulatory protein, arsR K21903 - - 0.00000000000000000000002916 104.0
CMS1_k127_4844827_5 Putative Fe-S cluster - - - 0.0000000000000000000004913 100.0
CMS1_k127_4844827_6 - - - - 0.000000000000181 82.0
CMS1_k127_4844827_7 DNA-binding transcription factor activity - - - 0.00000006143 59.0
CMS1_k127_4850498_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 529.0
CMS1_k127_4850498_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 355.0
CMS1_k127_4850498_2 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 353.0
CMS1_k127_4850498_3 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 303.0
CMS1_k127_4850498_4 Probable transposase K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005706 267.0
CMS1_k127_4850498_5 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000007934 246.0
CMS1_k127_4850498_6 nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000009087 199.0
CMS1_k127_4850498_7 - - - - 0.000000000000000000000000000000000000000004513 161.0
CMS1_k127_4850498_8 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000002212 138.0
CMS1_k127_4850498_9 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07006 - - 0.000000000000001957 81.0
CMS1_k127_4870184_0 Protein of unknown function DUF86 - - - 0.0000000000000000000000000001853 118.0
CMS1_k127_4870184_1 PFAM DNA polymerase, beta domain protein region K07075 - - 0.00000000000000000000000001256 111.0
CMS1_k127_4870184_2 - - - - 0.00000000001572 74.0
CMS1_k127_4882787_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01568,K04103 - 4.1.1.1,4.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 438.0
CMS1_k127_4882787_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 394.0
CMS1_k127_4882787_2 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008143 265.0
CMS1_k127_4882787_3 COG0433 Predicted ATPase - - - 0.000000000000000000000000000000000000000000000000000000003149 212.0
CMS1_k127_4882787_4 Transcriptional regulator K07721 - - 0.000000000000000000000000000001097 124.0
CMS1_k127_4882787_5 Psort location Cytoplasmic, score - - - 0.0000000000000000001694 90.0
CMS1_k127_4926770_0 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 291.0
CMS1_k127_4926770_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000001596 252.0
CMS1_k127_4926770_2 HWE histidine kinase - - - 0.0000000000000000000006961 96.0
CMS1_k127_4989152_0 Required for chromosome condensation and partitioning K03529 - - 2.528e-245 779.0
CMS1_k127_4989152_1 Phospholipid methyltransferase - - - 0.000000000000000000002486 101.0
CMS1_k127_5014291_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 5.179e-202 635.0
CMS1_k127_5014291_1 Probable transposase K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 357.0
CMS1_k127_5014291_2 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000004778 195.0
CMS1_k127_5014291_3 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000004536 123.0
CMS1_k127_50354_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 365.0
CMS1_k127_50354_1 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000002981 237.0
CMS1_k127_50354_2 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000003426 234.0
CMS1_k127_50354_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000008581 180.0
CMS1_k127_50354_4 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.000000000000000000000000000147 126.0
CMS1_k127_50354_5 nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000000000000000004419 91.0
CMS1_k127_50354_6 transcriptional - - - 0.000000000000452 81.0
CMS1_k127_50354_7 - - - - 0.000000002726 63.0
CMS1_k127_5047415_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 1.008e-222 701.0
CMS1_k127_5047415_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 2.818e-202 640.0
CMS1_k127_5047415_10 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 305.0
CMS1_k127_5047415_11 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 289.0
CMS1_k127_5047415_12 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 287.0
CMS1_k127_5047415_13 PFAM glutamate synthase alpha subunit K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003399 285.0
CMS1_k127_5047415_14 serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001835 281.0
CMS1_k127_5047415_15 COG0437 Fe-S-cluster-containing hydrogenase components 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000005784 234.0
CMS1_k127_5047415_16 KH domain protein K06961 - - 0.0000000000000000000000000000000000000000000000000000000002599 207.0
CMS1_k127_5047415_17 Protein of unknown function (DUF1699) - - - 0.000000000000000000000000000000000000000000000000001618 185.0
CMS1_k127_5047415_18 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000000318 192.0
CMS1_k127_5047415_19 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000000000004974 153.0
CMS1_k127_5047415_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005865 610.0
CMS1_k127_5047415_20 - - - - 0.0000000000000000000000000000003856 127.0
CMS1_k127_5047415_21 C-terminal AAA-associated domain - - - 0.0000000000000000000009963 100.0
CMS1_k127_5047415_22 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000001242 98.0
CMS1_k127_5047415_23 Probable transposase K07496 - - 0.000000000000000000003466 96.0
CMS1_k127_5047415_25 - - - - 0.000000000000001822 78.0
CMS1_k127_5047415_26 denitrification pathway - - - 0.0000000000002208 81.0
CMS1_k127_5047415_27 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000001081 72.0
CMS1_k127_5047415_28 Cytochrome c554 and c-prime K03620 - - 0.000000003783 68.0
CMS1_k127_5047415_29 Rubrerythrin - - - 0.000001248 57.0
CMS1_k127_5047415_3 Has ATPase and non-specific DNA-binding activities K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 590.0
CMS1_k127_5047415_30 Chagasin family peptidase inhibitor I42 K14475 - - 0.000002543 53.0
CMS1_k127_5047415_4 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 541.0
CMS1_k127_5047415_5 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 535.0
CMS1_k127_5047415_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 458.0
CMS1_k127_5047415_7 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 397.0
CMS1_k127_5047415_8 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 372.0
CMS1_k127_5047415_9 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K02588,K21610 - 1.18.6.1,6.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 336.0
CMS1_k127_5074266_0 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 494.0
CMS1_k127_5074266_1 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 313.0
CMS1_k127_5074266_11 DsrE/DsrF-like family K07235 - - 0.0000000000000001417 84.0
CMS1_k127_5074266_12 Sulfurtransferase TusA - - - 0.00000000000001017 76.0
CMS1_k127_5074266_13 - - - - 0.0000009138 59.0
CMS1_k127_5074266_14 DsrE/DsrF-like family - - - 0.00001102 51.0
CMS1_k127_5074266_15 protein involved in the oxidation of intracellular sulfur K07236 - - 0.0005154 48.0
CMS1_k127_5074266_2 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003261 268.0
CMS1_k127_5074266_3 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001161 258.0
CMS1_k127_5074266_4 cytochrome complex assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000001579 236.0
CMS1_k127_5074266_5 Belongs to the UPF0200 family - - - 0.00000000000000000000000000000000000000000000000000000000005329 209.0
CMS1_k127_5074266_6 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000002309 173.0
CMS1_k127_5074266_7 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000001946 168.0
CMS1_k127_5074266_8 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000001723 109.0
CMS1_k127_5074266_9 RNA binding K09736 - - 0.0000000000000000000000001242 111.0
CMS1_k127_5084687_0 PFAM Semialdehyde dehydrogenase NAD - binding K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 520.0
CMS1_k127_5084687_1 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 507.0
CMS1_k127_5084687_10 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000003443 259.0
CMS1_k127_5084687_11 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.0000000000000000000000000000000000000000000000000000000000000000002024 235.0
CMS1_k127_5084687_12 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000006793 235.0
CMS1_k127_5084687_13 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000008126 227.0
CMS1_k127_5084687_14 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.0000000000000000000000000000000000000000000000000000000000006552 214.0
CMS1_k127_5084687_15 Crossover junction endodeoxyribonuclease RuvC K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000001623 206.0
CMS1_k127_5084687_16 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000034 197.0
CMS1_k127_5084687_17 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.0000000000000000000000000000000000002792 142.0
CMS1_k127_5084687_18 - - - - 0.00000000000000000000000000000000005736 139.0
CMS1_k127_5084687_19 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000000000000000000000000003319 132.0
CMS1_k127_5084687_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 459.0
CMS1_k127_5084687_20 4Fe-4S binding domain - - - 0.0000000000000000007781 86.0
CMS1_k127_5084687_21 Predicted RNA-binding protein K06964 - - 0.000003815 50.0
CMS1_k127_5084687_22 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0001727 45.0
CMS1_k127_5084687_3 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 460.0
CMS1_k127_5084687_4 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 452.0
CMS1_k127_5084687_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008817 428.0
CMS1_k127_5084687_6 PFAM Aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 422.0
CMS1_k127_5084687_7 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 358.0
CMS1_k127_5084687_8 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007997 282.0
CMS1_k127_5084687_9 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005216 265.0
CMS1_k127_512004_0 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934 - 2.1.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 308.0
CMS1_k127_512004_1 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000005379 212.0
CMS1_k127_512004_2 PFAM cobalamin (vitamin B12) biosynthesis CbiG protein K02189 - 3.7.1.12 0.00000000000005274 78.0
CMS1_k127_5130745_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1581.0
CMS1_k127_5130745_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 494.0
CMS1_k127_5130745_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000005677 184.0
CMS1_k127_5130745_11 Belongs to the UPF0212 family K09731 - - 0.00000000000000000000000000000000000000000005891 163.0
CMS1_k127_5130745_12 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000001607 115.0
CMS1_k127_5130745_13 Protein of unknown function (DUF357) K09728 - - 0.00000000000000000000000006561 111.0
CMS1_k127_5130745_14 Mo-molybdopterin cofactor metabolic process - - - 0.00000005311 56.0
CMS1_k127_5130745_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 492.0
CMS1_k127_5130745_3 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 414.0
CMS1_k127_5130745_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 347.0
CMS1_k127_5130745_5 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 307.0
CMS1_k127_5130745_6 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001804 279.0
CMS1_k127_5130745_7 SMART regulatory protein AsnC Lrp family K22225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001356 245.0
CMS1_k127_5130745_8 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000005575 236.0
CMS1_k127_5130745_9 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000000005378 205.0
CMS1_k127_5230606_0 PFAM PilT protein domain protein K06865 - - 2.31e-218 694.0
CMS1_k127_5230606_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 498.0
CMS1_k127_5230606_2 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 342.0
CMS1_k127_5343091_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 7.977e-200 633.0
CMS1_k127_5343091_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007436 594.0
CMS1_k127_5343091_10 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000003984 181.0
CMS1_k127_5343091_11 Peptidase domain protein - - - 0.0000000000000000000000000000000000000000000001169 171.0
CMS1_k127_5343091_12 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.00000000000000000000000000000000000000000004059 165.0
CMS1_k127_5343091_13 Non-histone chromosomal protein MC1 - - - 0.000000000000000000000000000000000000000007897 154.0
CMS1_k127_5343091_14 - - - - 0.00000000000000000000000000000000000000001516 156.0
CMS1_k127_5343091_15 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000000007333 161.0
CMS1_k127_5343091_16 Subtilase family K13277 - - 0.0000000000000000000000000000000005805 134.0
CMS1_k127_5343091_17 - - - - 0.000000000000000000000000000000003044 132.0
CMS1_k127_5343091_18 - - - - 0.0000000000000000000000000002039 131.0
CMS1_k127_5343091_19 - K00960 - 2.7.7.6 0.00000000000000000000000001821 108.0
CMS1_k127_5343091_2 Beta-Casp domain K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 489.0
CMS1_k127_5343091_20 - K00960 - 2.7.7.6 0.000000000000000000000009854 100.0
CMS1_k127_5343091_21 Protein of unknown function (DUF2551) - - - 0.00000000000000000000004846 102.0
CMS1_k127_5343091_22 acid phosphatase activity - - - 0.000000000000002022 79.0
CMS1_k127_5343091_24 alpha-galactosidase K01179,K01183 - 3.2.1.14,3.2.1.4 0.0000001073 65.0
CMS1_k127_5343091_26 Belongs to the peptidase S8 family K01342,K14645 - 3.4.21.62 0.0009868 47.0
CMS1_k127_5343091_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 366.0
CMS1_k127_5343091_4 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 322.0
CMS1_k127_5343091_5 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001243 280.0
CMS1_k127_5343091_6 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000007388 259.0
CMS1_k127_5343091_7 PFAM metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008788 248.0
CMS1_k127_5343091_8 Winged helix-turn-helix DNA-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000001148 229.0
CMS1_k127_5343091_9 Necessary for normal cell division and for the maintenance of normal septation - - - 0.000000000000000000000000000000000000000000000000000000000000001696 222.0
CMS1_k127_5399113_0 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.0 1075.0
CMS1_k127_5399113_1 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 596.0
CMS1_k127_5399113_10 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000007272 250.0
CMS1_k127_5399113_11 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000138 235.0
CMS1_k127_5399113_12 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000001572 231.0
CMS1_k127_5399113_13 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000003226 224.0
CMS1_k127_5399113_14 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000001836 159.0
CMS1_k127_5399113_15 Belongs to the UPF0147 family K09721 - - 0.00000000000000000000000000009591 118.0
CMS1_k127_5399113_16 Fe-S-cluster oxidoreductase K06940 - - 0.0000000000000000000000003884 108.0
CMS1_k127_5399113_17 - - - - 0.00000000000000000001535 94.0
CMS1_k127_5399113_18 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) K07143 - - 0.00000000000000002282 87.0
CMS1_k127_5399113_19 Putative zinc- or iron-chelating domain K06940 - - 0.0000004895 55.0
CMS1_k127_5399113_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 527.0
CMS1_k127_5399113_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 448.0
CMS1_k127_5399113_4 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 351.0
CMS1_k127_5399113_5 PINc domain ribonuclease K09006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 316.0
CMS1_k127_5399113_6 SWIM zinc finger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 293.0
CMS1_k127_5399113_7 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000006439 266.0
CMS1_k127_5399113_8 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000008012 269.0
CMS1_k127_5399113_9 Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.0000000000000000000000000000000000000000000000000000000000000000000000005547 249.0
CMS1_k127_5400492_0 SMART Elongator protein 3 MiaB NifB - - - 4.521e-221 697.0
CMS1_k127_5400492_1 - - - - 0.0004732 49.0
CMS1_k127_5400520_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 1.803e-255 806.0
CMS1_k127_5400520_1 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 6.017e-217 687.0
CMS1_k127_5400520_10 TIGRFAM cell division ATPase MinD K03609 - - 0.00000000000000000000000000000000000000000000007517 177.0
CMS1_k127_5400520_11 PFAM molydopterin dinucleotide-binding region K00203 - 1.2.7.12 0.000000000000000000000000000000000000000003105 161.0
CMS1_k127_5400520_12 - - - - 0.00000000000000000000000000000000001933 143.0
CMS1_k127_5400520_13 Protein of unknown function (DUF356) K09727 - - 0.00000000000000000000000000000004141 129.0
CMS1_k127_5400520_14 - - - - 0.0000000000000000000000000001615 131.0
CMS1_k127_5400520_15 Domain of unknown function DUF11 - - - 0.0000000000000000000000000001899 131.0
CMS1_k127_5400520_16 PFAM Peptidase S24 S26A S26B, conserved region K13280 - 3.4.21.89 0.000000000000000000000000002417 121.0
CMS1_k127_5400520_17 gluconolactonase activity K01448,K02395,K08651 - 3.4.21.66,3.5.1.28 0.000000000000000000000007276 114.0
CMS1_k127_5400520_18 - - - - 0.00000000000000000000005601 110.0
CMS1_k127_5400520_19 PFAM Deoxyribonuclease rho motif-related TRAM - - - 0.00000000000000000000341 94.0
CMS1_k127_5400520_2 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 576.0
CMS1_k127_5400520_20 - - - - 0.000000000000000000003531 102.0
CMS1_k127_5400520_21 von Willebrand factor, type A K07114 - - 0.0000000000000000003344 102.0
CMS1_k127_5400520_22 - - - - 0.00000000000000004356 95.0
CMS1_k127_5400520_23 - - - - 0.00000000000000006191 88.0
CMS1_k127_5400520_24 - - - - 0.0000000000000004184 92.0
CMS1_k127_5400520_25 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.00000000000002883 85.0
CMS1_k127_5400520_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 443.0
CMS1_k127_5400520_4 DNA polymerase beta domain protein region K09717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 394.0
CMS1_k127_5400520_5 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 408.0
CMS1_k127_5400520_6 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007984 325.0
CMS1_k127_5400520_7 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 313.0
CMS1_k127_5400520_8 Glycoside-hydrolase family GH114 K01884 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 289.0
CMS1_k127_5400520_9 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006452 249.0
CMS1_k127_5425374_0 Phosphofructokinase K00895,K21071 - 2.7.1.11,2.7.1.90 3.165e-237 741.0
CMS1_k127_5425374_1 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000004063 176.0
CMS1_k127_5433311_0 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000003964 257.0
CMS1_k127_5433311_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000002109 241.0
CMS1_k127_5433311_2 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.00000000000000000000000000000000000000000007396 163.0
CMS1_k127_5437591_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K22167 - 1.5.98.3 9.285e-233 737.0
CMS1_k127_5437591_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 2.048e-204 647.0
CMS1_k127_5437591_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 315.0
CMS1_k127_5437591_11 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 291.0
CMS1_k127_5437591_12 RecA-superfamily ATPases implicated in signal transduction K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001172 268.0
CMS1_k127_5437591_13 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001088 254.0
CMS1_k127_5437591_14 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000004008 246.0
CMS1_k127_5437591_15 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000002892 238.0
CMS1_k127_5437591_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000002914 220.0
CMS1_k127_5437591_17 Serine dehydrogenase proteinase - - - 0.000000000000000000000000000000000000000000000000000000003739 209.0
CMS1_k127_5437591_18 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000001314 192.0
CMS1_k127_5437591_19 flagella protein K07327,K07328 - - 0.000000000000000000000000000000000000000000000000008403 194.0
CMS1_k127_5437591_2 Proton-conducting membrane transporter K22168 - 1.5.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 579.0
CMS1_k127_5437591_20 Patched family K07003 - - 0.00000000000000000000000000000000000000000000000005216 202.0
CMS1_k127_5437591_21 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000002701 155.0
CMS1_k127_5437591_22 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K22166 - 1.5.98.3 0.0000000000000000000000000000000007301 133.0
CMS1_k127_5437591_23 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.000000000000000000000000000000003533 134.0
CMS1_k127_5437591_24 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000004395 142.0
CMS1_k127_5437591_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000005322 124.0
CMS1_k127_5437591_26 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000006938 115.0
CMS1_k127_5437591_27 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000002006 117.0
CMS1_k127_5437591_28 4Fe-4S dicluster domain K22164 - 1.5.98.3 0.000000000000000000000000002073 116.0
CMS1_k127_5437591_29 - - - - 0.00000000000000000000001097 106.0
CMS1_k127_5437591_3 Proton-conducting membrane transporter K22169 - 1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 515.0
CMS1_k127_5437591_30 COG1361 S-layer domain - - - 0.0000000000000000000002225 110.0
CMS1_k127_5437591_31 - - - - 0.000000000000000000003388 103.0
CMS1_k127_5437591_32 Signal transduction histidine kinase - - - 0.0000000000000000002959 96.0
CMS1_k127_5437591_33 chemotaxis protein K03406 - - 0.00000000000000001801 94.0
CMS1_k127_5437591_34 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000002891 75.0
CMS1_k127_5437591_35 F420H2 dehydrogenase subunit FpoO K22170 - 1.5.98.3 0.000000000002846 72.0
CMS1_k127_5437591_36 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000005993 64.0
CMS1_k127_5437591_37 Universal stress protein family - - - 0.000000001024 60.0
CMS1_k127_5437591_38 membrane protein (DUF2078) K08982 - - 0.000000001292 61.0
CMS1_k127_5437591_39 E-Z type HEAT repeats - - - 0.000000003816 70.0
CMS1_k127_5437591_4 Dihydrouridine synthase (Dus) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 459.0
CMS1_k127_5437591_40 - - - - 0.000000009479 62.0
CMS1_k127_5437591_5 pfam abc1 K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 450.0
CMS1_k127_5437591_6 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 414.0
CMS1_k127_5437591_7 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 426.0
CMS1_k127_5437591_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 394.0
CMS1_k127_5437591_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 325.0
CMS1_k127_5449381_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 4.428e-254 795.0
CMS1_k127_5449381_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 582.0
CMS1_k127_5449381_10 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.000000000000000000000000000000000000000000000000003633 184.0
CMS1_k127_5449381_11 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.0000000000000000000000000000000003848 135.0
CMS1_k127_5449381_12 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000000000004067 123.0
CMS1_k127_5449381_13 PAS domain K03406 - - 0.00000000000000000000000001956 113.0
CMS1_k127_5449381_14 Binds to the 23S rRNA K02896 - - 0.00000000000000000000000001984 109.0
CMS1_k127_5449381_15 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000006711 107.0
CMS1_k127_5449381_16 - - - - 0.0000000000000001824 90.0
CMS1_k127_5449381_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 407.0
CMS1_k127_5449381_3 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 365.0
CMS1_k127_5449381_4 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000007816 265.0
CMS1_k127_5449381_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000005038 228.0
CMS1_k127_5449381_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000004058 227.0
CMS1_k127_5449381_7 PFAM UbiA prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001408 220.0
CMS1_k127_5449381_8 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000003447 209.0
CMS1_k127_5449381_9 Domain of unknown function (DUF1724) - - - 0.0000000000000000000000000000000000000000000000000000001127 205.0
CMS1_k127_5458919_0 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008706 241.0
CMS1_k127_5458919_1 by GeneMark - - - 0.000000000000000000000000000000000000000009788 160.0
CMS1_k127_5458919_2 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000001484 129.0
CMS1_k127_5458919_4 - - - - 0.00002779 55.0
CMS1_k127_5465963_0 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 344.0
CMS1_k127_5465963_1 ATPase involved in DNA repair K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 361.0
CMS1_k127_5465963_2 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 293.0
CMS1_k127_5465963_3 NurA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001436 290.0
CMS1_k127_5465963_4 - - - - 0.0000000000000000000000001375 112.0
CMS1_k127_5483594_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 1.582e-205 644.0
CMS1_k127_5483594_1 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 546.0
CMS1_k127_5483594_2 Belongs to the GbsR family K22109 - - 0.00000000000000000000000000000000000000000000000000000002183 202.0
CMS1_k127_5483594_3 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000001236 124.0
CMS1_k127_5483594_4 PFAM Integrase, catalytic core, phage - - - 0.0003961 46.0
CMS1_k127_5505415_0 UbiD family K03182 - 4.1.1.98 5.397e-202 638.0
CMS1_k127_5505415_1 Cys/Met metabolism PLP-dependent enzyme K01758,K01761 - 4.4.1.1,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 390.0
CMS1_k127_5505415_2 MgtC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 342.0
CMS1_k127_5505415_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000002719 266.0
CMS1_k127_5505415_4 NifU-like domain - - - 0.00000000257 61.0
CMS1_k127_5505415_5 SigmaK-factor processing regulatory protein BofA - - - 0.0000008978 54.0
CMS1_k127_5505415_6 - - - - 0.0001062 53.0
CMS1_k127_5514348_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 7.282e-299 924.0
CMS1_k127_5514348_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 2.16e-269 832.0
CMS1_k127_5514348_10 hydrolase K04794 - 3.1.1.29 0.00000000000000000000000000000000000000000002943 163.0
CMS1_k127_5514348_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000000000000000000000003489 166.0
CMS1_k127_5514348_12 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000001053 151.0
CMS1_k127_5514348_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000000000000000000266 124.0
CMS1_k127_5514348_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000001775 118.0
CMS1_k127_5514348_15 - - - - 0.0000000000000000000004572 102.0
CMS1_k127_5514348_16 ATP synthase subunit C K02124 - - 0.0000000000000000000005576 97.0
CMS1_k127_5514348_17 - - - - 0.00000000000111 75.0
CMS1_k127_5514348_18 H subunit K02107 - - 0.000000000001609 71.0
CMS1_k127_5514348_19 - - - - 0.00000004219 60.0
CMS1_k127_5514348_2 - - - - 2.518e-224 712.0
CMS1_k127_5514348_20 - - - - 0.00000004805 58.0
CMS1_k127_5514348_21 Lactonase, 7-bladed beta-propeller - - - 0.0001228 54.0
CMS1_k127_5514348_3 Type II/IV secretion system protein - - - 2.038e-218 701.0
CMS1_k127_5514348_4 Radical SAM K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 510.0
CMS1_k127_5514348_5 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 499.0
CMS1_k127_5514348_6 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 475.0
CMS1_k127_5514348_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 349.0
CMS1_k127_5514348_8 SMART regulatory protein AsnC Lrp family K22225 - - 0.00000000000000000000000000000000000000000000000000003084 191.0
CMS1_k127_5514348_9 PFAM Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000003611 191.0
CMS1_k127_5554246_0 PFAM Aldehyde dehydrogenase K22187 - - 2.463e-226 710.0
CMS1_k127_5554246_1 Aminotransferase class-III K00823,K00836 - 2.6.1.19,2.6.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 558.0
CMS1_k127_5554246_2 S-layer protein - - - 0.00000000000000000000000000000000009945 144.0
CMS1_k127_5554246_3 - - - - 0.00000000000008966 73.0
CMS1_k127_5554246_4 Roadblock LC7 family protein K07131 - - 0.00000001294 62.0
CMS1_k127_5554246_5 Dimerisation domain of Zinc Transporter - - - 0.0000001135 56.0
CMS1_k127_5571021_0 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 398.0
CMS1_k127_5571021_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 317.0
CMS1_k127_5571021_2 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.00000000000000000000000000000000000000000000000000000071 209.0
CMS1_k127_5571021_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000001009 184.0
CMS1_k127_5571021_4 - - - - 0.0000000000000000000000000000461 117.0
CMS1_k127_5571021_5 CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000004279 112.0
CMS1_k127_5572295_0 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0 1261.0
CMS1_k127_5572295_1 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 2.035e-217 686.0
CMS1_k127_5572295_10 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 346.0
CMS1_k127_5572295_11 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003723 256.0
CMS1_k127_5572295_12 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002021 244.0
CMS1_k127_5572295_13 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000001985 238.0
CMS1_k127_5572295_14 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000009939 226.0
CMS1_k127_5572295_15 COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000001066 224.0
CMS1_k127_5572295_16 poly(R)-hydroxyalkanoic acid synthase subunit PhaC K03821 - - 0.0000000000000000000000000000000000000000000000000000000000001661 226.0
CMS1_k127_5572295_17 6-carboxyhexanoate-CoA ligase activity K00652,K01906 - 2.3.1.47,6.2.1.14 0.000000000000000000000000000000000000000000000000000000000406 211.0
CMS1_k127_5572295_18 BioY protein K03523 - - 0.00000000000000000000000000000000000000000000000000003967 195.0
CMS1_k127_5572295_19 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000007719 187.0
CMS1_k127_5572295_2 Cys/Met metabolism PLP-dependent enzyme K19793 - 2.6.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 548.0
CMS1_k127_5572295_20 PIN domain of ribonuclease K07060 - - 0.000000000000000000000000000000000000000000001007 169.0
CMS1_k127_5572295_21 Belongs to the UPF0146 family K09713 - - 0.00000000000000000000000000000000000000006706 154.0
CMS1_k127_5572295_22 - - - - 0.00000000000000000000000000894 121.0
CMS1_k127_5572295_23 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000002114 77.0
CMS1_k127_5572295_24 - - - - 0.00000000001907 73.0
CMS1_k127_5572295_25 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000002805 70.0
CMS1_k127_5572295_26 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000003696 65.0
CMS1_k127_5572295_27 Protein of unknown function (DUF2769) - - - 0.0000000004722 64.0
CMS1_k127_5572295_28 Family of unknown function (DUF5371) - - - 0.0000001646 54.0
CMS1_k127_5572295_29 - - - - 0.0000005306 62.0
CMS1_k127_5572295_3 PFAM type II secretion system protein E K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 529.0
CMS1_k127_5572295_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01906 - 2.3.1.29,2.3.1.47,6.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 402.0
CMS1_k127_5572295_5 type II secretion system protein K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 389.0
CMS1_k127_5572295_6 PFAM peptidase M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 373.0
CMS1_k127_5572295_7 PFAM Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 368.0
CMS1_k127_5572295_8 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 355.0
CMS1_k127_5572295_9 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 342.0
CMS1_k127_5589908_0 in RNase L inhibitor, RLI K06174 - - 4.747e-268 835.0
CMS1_k127_5589908_1 PFAM type II secretion system protein E K07332 - - 1.491e-238 760.0
CMS1_k127_5589908_10 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 296.0
CMS1_k127_5589908_11 KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 301.0
CMS1_k127_5589908_12 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002915 286.0
CMS1_k127_5589908_13 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001902 254.0
CMS1_k127_5589908_14 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002246 252.0
CMS1_k127_5589908_15 V4R K07013 - - 0.00000000000000000000000000000000000000000000000000000000000000008157 229.0
CMS1_k127_5589908_16 transmembrane signaling receptor activity K02660,K03406,K03776,K11525 - - 0.0000000000000000000000000000000000000000000000000000000000000001719 224.0
CMS1_k127_5589908_17 cheY-homologous receiver domain K07658 - - 0.000000000000000000000000000000000000000000000002261 178.0
CMS1_k127_5589908_18 cheY-homologous receiver domain K07668 - - 0.000000000000000000000000000000000000000000001047 167.0
CMS1_k127_5589908_19 - - - - 0.00000000000000000000000006704 110.0
CMS1_k127_5589908_2 type II secretion system protein K07333 - - 3.038e-228 724.0
CMS1_k127_5589908_20 DNA-binding transcription factor activity K03892 - - 0.0000000000000000000001331 99.0
CMS1_k127_5589908_21 RNase L inhibitor, RLI - - - 0.0000000000000000006451 90.0
CMS1_k127_5589908_22 thiolester hydrolase activity K06889 - - 0.0000000000000004544 86.0
CMS1_k127_5589908_23 Integral membrane sensor signal transduction histidine kinase K07680,K07778,K11617,K14988 - 2.7.13.3 0.0000000000005231 78.0
CMS1_k127_5589908_24 - - - - 0.0000003269 53.0
CMS1_k127_5589908_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 415.0
CMS1_k127_5589908_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007874 426.0
CMS1_k127_5589908_5 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11779,K11784 - 1.21.98.1,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 396.0
CMS1_k127_5589908_6 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 388.0
CMS1_k127_5589908_7 TIGRFAM cell division ATPase MinD K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 336.0
CMS1_k127_5589908_8 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 308.0
CMS1_k127_5589908_9 PFAM dihydropteroate synthase, DHPS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 302.0
CMS1_k127_5590709_0 Probable transposase K07496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 302.0
CMS1_k127_5590709_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003867 277.0
CMS1_k127_5590709_2 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001198 225.0
CMS1_k127_5590709_3 Universal stress protein family - - - 0.0000000000000000000000000000000000000000001446 163.0
CMS1_k127_5590709_4 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000001162 120.0
CMS1_k127_5590709_5 - - - - 0.0000008588 53.0
CMS1_k127_560563_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 9.762e-272 851.0
CMS1_k127_560563_1 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 0.00000000000000000000000000000000000000725 149.0
CMS1_k127_560563_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000005558 106.0
CMS1_k127_560563_3 Flavodoxin - - - 0.000000000000000000000002097 107.0
CMS1_k127_560563_4 - - - - 0.00000000000004871 78.0
CMS1_k127_560563_5 - - - - 0.0000000000008086 75.0
CMS1_k127_560563_6 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.00000000005829 66.0
CMS1_k127_560563_7 - - - - 0.00000003788 63.0
CMS1_k127_5622827_0 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 8.051e-194 615.0
CMS1_k127_5622827_1 small GTP-binding protein K06945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 422.0
CMS1_k127_5622827_10 Thioredoxin domain - - - 0.00000000000000000006103 93.0
CMS1_k127_5622827_11 PFAM Nitrate reductase gamma subunit - - - 0.000000000000006329 84.0
CMS1_k127_5622827_12 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 - - 0.00000000000001276 76.0
CMS1_k127_5622827_13 Roadblock LC7 family protein K06945,K07131 - - 0.0000000000001837 75.0
CMS1_k127_5622827_14 Mechanosensitive ion channel K16052 - - 0.000000000004794 68.0
CMS1_k127_5622827_15 - - - - 0.000000000009319 66.0
CMS1_k127_5622827_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 407.0
CMS1_k127_5622827_3 PFAM Radical SAM domain protein K03716 - 4.1.99.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 342.0
CMS1_k127_5622827_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K03885,K17870 - 1.6.3.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 302.0
CMS1_k127_5622827_5 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 286.0
CMS1_k127_5622827_6 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.00000000000000000000000000000000000000000000000000000008755 199.0
CMS1_k127_5622827_7 - - - - 0.0000000000000000000000000000000000000000000000000000001141 199.0
CMS1_k127_5622827_8 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000008756 144.0
CMS1_k127_5622827_9 Belongs to the PDCD5 family K06875 - - 0.00000000000000000000000000000004195 129.0
CMS1_k127_5678590_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.576e-219 692.0
CMS1_k127_5678590_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.569e-215 675.0
CMS1_k127_5678590_10 Domain of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000003113 232.0
CMS1_k127_5678590_11 ZPR1-related zinc finger protein K06874 - - 0.000000000000000000000000000000000000000000000000000000000000000008353 231.0
CMS1_k127_5678590_12 PFAM PUA domain containing protein K07575 - - 0.0000000000000000000000000000000000000000000007344 170.0
CMS1_k127_5678590_13 electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000006431 166.0
CMS1_k127_5678590_14 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.00000000000000000000000000000000000000004755 156.0
CMS1_k127_5678590_15 Zn-ribbon containing protein K07163 - - 0.000000000000000000000000000000000000002577 150.0
CMS1_k127_5678590_16 Pfam:DUF552 K09152 - - 0.000000000000000000000000000000000007625 139.0
CMS1_k127_5678590_17 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000009116 117.0
CMS1_k127_5678590_18 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.0000000000000000000000000002939 115.0
CMS1_k127_5678590_19 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.0000000000000000000000000007319 115.0
CMS1_k127_5678590_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 604.0
CMS1_k127_5678590_20 binds to the 23S rRNA K02922 - - 0.000000000000000000004832 93.0
CMS1_k127_5678590_21 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000003155 83.0
CMS1_k127_5678590_22 PFAM Rhomboid family protein - - - 0.00000000000001955 81.0
CMS1_k127_5678590_23 - - - - 0.0000000000006952 75.0
CMS1_k127_5678590_24 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.0000000001837 65.0
CMS1_k127_5678590_3 Psort location Cytoplasmic, score K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 521.0
CMS1_k127_5678590_4 FAD dependent oxidoreductase K00313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 398.0
CMS1_k127_5678590_5 3-hydroxyacyl-CoA dehydrogenase K00074,K01782 - 1.1.1.157,1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 376.0
CMS1_k127_5678590_6 PFAM GTP-binding protein HSR1-related K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 332.0
CMS1_k127_5678590_7 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005757 280.0
CMS1_k127_5678590_8 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000001651 249.0
CMS1_k127_5678590_9 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000004109 245.0
CMS1_k127_5735914_0 Baseplate J-like protein - - - 3.241e-234 748.0
CMS1_k127_5735914_1 PFAM AAA ATPase central domain protein - - - 6.037e-226 717.0
CMS1_k127_5735914_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001019 271.0
CMS1_k127_5735914_11 photosystem II stabilization K02237 - - 0.00000000000000000000000000000000000000000000000000000000000000000002238 247.0
CMS1_k127_5735914_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003163 252.0
CMS1_k127_5735914_13 cell septum assembly - - - 0.00000000000000000000000000000000000000000000003337 183.0
CMS1_k127_5735914_14 - - - - 0.0000000000000000000000000000000000000000000003154 168.0
CMS1_k127_5735914_15 Gene 25-like lysozyme K06903 - - 0.00000000000000000000000000000000000000006712 159.0
CMS1_k127_5735914_16 cell septum assembly - - - 0.00000000000000000000000000000000000006494 157.0
CMS1_k127_5735914_17 cell septum assembly - - - 0.0000000000000000000000000000000127 143.0
CMS1_k127_5735914_18 LysM domain - - - 0.00000000000000000000000000000003502 127.0
CMS1_k127_5735914_19 - - - - 0.0000000000000000000000001384 108.0
CMS1_k127_5735914_2 Baseplate J-like protein - - - 1.104e-214 700.0
CMS1_k127_5735914_20 Probable zinc-ribbon domain - - - 0.000000000002279 72.0
CMS1_k127_5735914_21 CoA binding domain K06929 - - 0.000000008808 65.0
CMS1_k127_5735914_3 amine oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 608.0
CMS1_k127_5735914_4 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 585.0
CMS1_k127_5735914_5 Late control gene D protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 480.0
CMS1_k127_5735914_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 489.0
CMS1_k127_5735914_7 Protein of unknown function (DUF4255) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 358.0
CMS1_k127_5735914_8 Rhs element vgr protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 282.0
CMS1_k127_5735914_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005626 280.0
CMS1_k127_57629_0 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 514.0
CMS1_k127_57629_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 308.0
CMS1_k127_57629_10 SMART Tetratricopeptide - - - 0.00000000000000000000000002128 123.0
CMS1_k127_57629_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 303.0
CMS1_k127_57629_3 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K22162 - 1.5.7.2,1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 312.0
CMS1_k127_57629_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000002554 244.0
CMS1_k127_57629_5 cytidyltransferase-related domain K00952 - 2.7.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000006991 242.0
CMS1_k127_57629_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000001937 226.0
CMS1_k127_57629_7 Located on the platform of the 30S subunit K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000005797 220.0
CMS1_k127_57629_8 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000006239 189.0
CMS1_k127_57629_9 S-layer protein - - - 0.00000000000000000000000000000003325 136.0
CMS1_k127_5788040_0 type ii restriction enzyme K01155 - 3.1.21.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 536.0
CMS1_k127_5788040_1 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 507.0
CMS1_k127_5788040_10 Cytochrome C biogenesis protein K02200 - - 0.00000000001374 70.0
CMS1_k127_5788040_11 Cytochrome C biogenesis protein K02200 - - 0.00000000001656 70.0
CMS1_k127_5788040_12 - - - - 0.00000000002905 70.0
CMS1_k127_5788040_13 Protein of unknown function with PCYCGC motif - - - 0.000000001101 65.0
CMS1_k127_5788040_14 - - - - 0.0000009743 60.0
CMS1_k127_5788040_15 - - - - 0.000006324 55.0
CMS1_k127_5788040_16 Protein of unknown function (DUF2933) - - - 0.00005725 48.0
CMS1_k127_5788040_17 - - - - 0.0001472 51.0
CMS1_k127_5788040_18 Sphaeroforma arctica JP610 - - - 0.0002753 53.0
CMS1_k127_5788040_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 318.0
CMS1_k127_5788040_3 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000005361 200.0
CMS1_k127_5788040_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000222 188.0
CMS1_k127_5788040_5 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.000000000000000000000000000000000621 139.0
CMS1_k127_5788040_6 Membrane protein of unknown function DUF63 - - - 0.000000000000000000000000000000008835 138.0
CMS1_k127_5788040_7 nitrous-oxide reductase activity - - - 0.0000000000000000000000000006956 118.0
CMS1_k127_5788040_8 PFAM YHS domain - - - 0.00000000000000009004 81.0
CMS1_k127_5788040_9 CcmE K02197 - - 0.000000000000003221 81.0
CMS1_k127_5790893_0 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 456.0
CMS1_k127_5790893_1 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008526 449.0
CMS1_k127_5790893_10 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000000000923 128.0
CMS1_k127_5790893_11 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000002884 134.0
CMS1_k127_5790893_12 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000006354 126.0
CMS1_k127_5790893_13 - - - - 0.0000000000000000000004294 99.0
CMS1_k127_5790893_14 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00578 - 2.1.1.86 0.000000000000000000002146 97.0
CMS1_k127_5790893_15 cheY-homologous receiver domain K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000000004311 96.0
CMS1_k127_5790893_16 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00582 - 2.1.1.86 0.000000000000000004005 86.0
CMS1_k127_5790893_17 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00583 - 2.1.1.86 0.000000000000000006937 85.0
CMS1_k127_5790893_18 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000006531 63.0
CMS1_k127_5790893_19 S-layer protein - - - 0.00000003399 60.0
CMS1_k127_5790893_2 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 418.0
CMS1_k127_5790893_20 COG0477 Permeases of the major facilitator superfamily - - - 0.0000001749 55.0
CMS1_k127_5790893_21 cell wall organization - - - 0.0001095 50.0
CMS1_k127_5790893_3 Methanogenesis marker protein 8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 374.0
CMS1_k127_5790893_4 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00581 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 360.0
CMS1_k127_5790893_5 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 306.0
CMS1_k127_5790893_6 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00580 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000001298 252.0
CMS1_k127_5790893_7 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00579 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000001786 235.0
CMS1_k127_5790893_8 COG0455 ATPases involved in chromosome partitioning - - - 0.0000000000000000000000000000000000000000000000000002144 194.0
CMS1_k127_5790893_9 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000000000003669 175.0
CMS1_k127_5799623_0 plastoquinone (Complex I) K12137 - - 1.458e-205 659.0
CMS1_k127_5799623_1 PFAM chaperonin Cpn60 TCP-1 K22447 - - 5.747e-202 642.0
CMS1_k127_5799623_10 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002457 279.0
CMS1_k127_5799623_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001682 258.0
CMS1_k127_5799623_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000003347 231.0
CMS1_k127_5799623_13 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000006444 231.0
CMS1_k127_5799623_14 - - - - 0.000000000000000000000000000000000000000000000000000000000007646 233.0
CMS1_k127_5799623_15 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000002467 205.0
CMS1_k127_5799623_16 Hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000005035 182.0
CMS1_k127_5799623_17 SNARE associated Golgi protein K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.0000000000000000000000000000000000000000000003251 171.0
CMS1_k127_5799623_18 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000002478 173.0
CMS1_k127_5799623_19 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000000006566 157.0
CMS1_k127_5799623_2 plastoquinone (Complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 617.0
CMS1_k127_5799623_20 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) K12143 - - 0.000000000000000000000002156 107.0
CMS1_k127_5799623_22 Lipoate-protein ligase K03800 - 6.3.1.20 0.0000000000002478 73.0
CMS1_k127_5799623_24 PFAM Universal stress protein family - - - 0.00000003489 61.0
CMS1_k127_5799623_25 oligosaccharyl transferase STT3 subunit - - - 0.00004496 55.0
CMS1_k127_5799623_3 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007979 543.0
CMS1_k127_5799623_4 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 546.0
CMS1_k127_5799623_5 plastoquinone (Complex I) K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 526.0
CMS1_k127_5799623_6 Domain of unknown function DUF87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 386.0
CMS1_k127_5799623_7 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 336.0
CMS1_k127_5799623_8 Formate hydrogenlyase subunit 4 K12138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 332.0
CMS1_k127_5799623_9 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 297.0
CMS1_k127_5801216_0 Belongs to the RtcB family K14415 - 6.5.1.3 7.292e-230 719.0
CMS1_k127_5801216_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 581.0
CMS1_k127_5801216_10 - - - - 0.00000000000000000000000000000003469 131.0
CMS1_k127_5801216_11 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.00000000000000000000000000001938 123.0
CMS1_k127_5801216_12 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000000000000000000000000001261 115.0
CMS1_k127_5801216_13 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000001779 117.0
CMS1_k127_5801216_14 protein conserved in archaea - - - 0.0000000000000000003826 90.0
CMS1_k127_5801216_15 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.00000000000000000252 84.0
CMS1_k127_5801216_16 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000000004677 87.0
CMS1_k127_5801216_17 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.000000000000000009264 83.0
CMS1_k127_5801216_18 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000008315 80.0
CMS1_k127_5801216_19 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.000002014 51.0
CMS1_k127_5801216_2 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 491.0
CMS1_k127_5801216_20 Possibly the antitoxin component of a - - - 0.00008782 48.0
CMS1_k127_5801216_3 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000568 265.0
CMS1_k127_5801216_4 methyltransferase small K07579 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001663 258.0
CMS1_k127_5801216_5 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000000000000000000000000000000000000000002215 234.0
CMS1_k127_5801216_6 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000000000000000000000000000000002678 181.0
CMS1_k127_5801216_7 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000000000000000000000009368 152.0
CMS1_k127_5801216_8 NfeD-like C-terminal, partner-binding - - - 0.00000000000000000000000000000000001745 139.0
CMS1_k127_5801216_9 Large family of predicted nucleotide-binding domains K07158 - - 0.00000000000000000000000000000002076 130.0
CMS1_k127_5803835_0 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007726 355.0
CMS1_k127_5803835_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 341.0
CMS1_k127_5803835_3 Pfam:DUF258 - - - 0.0000000000003433 69.0
CMS1_k127_5803835_4 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000001503 55.0
CMS1_k127_5847084_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.428e-257 803.0
CMS1_k127_5847084_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 7.604e-226 727.0
CMS1_k127_5847084_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 321.0
CMS1_k127_5847084_11 tRNAHis guanylyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 288.0
CMS1_k127_5847084_12 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001088 269.0
CMS1_k127_5847084_13 protein histidine kinase activity K07814,K11527 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000001247 274.0
CMS1_k127_5847084_14 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000006783 239.0
CMS1_k127_5847084_15 phosphate transporter K16331 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.000000000000000000000000000000000000000000000000000000000000000001537 239.0
CMS1_k127_5847084_16 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000001228 213.0
CMS1_k127_5847084_17 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000001035 129.0
CMS1_k127_5847084_18 PFAM PRC-barrel domain - - - 0.00000000000000000000000008011 109.0
CMS1_k127_5847084_19 flavodoxin - - - 0.0000000000000004314 86.0
CMS1_k127_5847084_2 Subtilase family K17734 - - 6.255e-216 729.0
CMS1_k127_5847084_20 Roadblock LC7 family protein K07131 - - 0.0000000000000005161 83.0
CMS1_k127_5847084_21 Subtilase family K17734 - - 0.00000000000001914 76.0
CMS1_k127_5847084_3 ATPases associated with a variety of cellular activities K00400 - - 4.648e-196 627.0
CMS1_k127_5847084_4 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 436.0
CMS1_k127_5847084_5 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 400.0
CMS1_k127_5847084_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 350.0
CMS1_k127_5847084_7 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 334.0
CMS1_k127_5847084_8 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 331.0
CMS1_k127_5847084_9 Phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 321.0
CMS1_k127_5857798_0 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001445 295.0
CMS1_k127_5857798_1 MCP methyltransferase, CheR-type K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000002337 131.0
CMS1_k127_5857798_2 Protein of unknown function (DUF2551) - - - 0.0000000000000000001249 92.0
CMS1_k127_5899263_0 PFAM type II secretion system protein E K07332 - - 1.361e-194 621.0
CMS1_k127_5899263_1 type II secretion system protein K07333 - - 0.000000000000000000000000000000000000000000000000000000000000001492 231.0
CMS1_k127_5899263_2 Domain of unknown function DUF11 - - - 0.00003326 56.0
CMS1_k127_5917873_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 1.999e-204 671.0
CMS1_k127_5917873_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 329.0
CMS1_k127_5917873_10 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000002254 124.0
CMS1_k127_5917873_11 - - - - 0.000000000000000000000000002373 114.0
CMS1_k127_5917873_12 - - - - 0.000000000000000000000002216 117.0
CMS1_k127_5917873_13 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000005221 102.0
CMS1_k127_5917873_14 Transport permease protein K01992 - - 0.00000000000000000003281 92.0
CMS1_k127_5917873_15 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000004422 88.0
CMS1_k127_5917873_16 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form - - - 0.00000000000000000751 92.0
CMS1_k127_5917873_17 helix_turn_helix ASNC type K03718 - - 0.0000000000000008669 83.0
CMS1_k127_5917873_18 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000001115 77.0
CMS1_k127_5917873_19 membrane-associated protein K03975 - - 0.0000004926 57.0
CMS1_k127_5917873_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000002614 240.0
CMS1_k127_5917873_3 pfam ammecr1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000008037 221.0
CMS1_k127_5917873_4 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000003182 222.0
CMS1_k127_5917873_5 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000002121 216.0
CMS1_k127_5917873_6 PFAM O-methyltransferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000005028 208.0
CMS1_k127_5917873_7 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000002135 201.0
CMS1_k127_5917873_8 cheY-homologous receiver domain K07658 - - 0.0000000000000000000000000000000000000000000000004288 180.0
CMS1_k127_5917873_9 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.000000000000000000000000000000000007913 140.0
CMS1_k127_5951010_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 1.922e-200 633.0
CMS1_k127_5951010_1 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 2.023e-194 614.0
CMS1_k127_5951010_10 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000003189 190.0
CMS1_k127_5951010_11 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000005732 194.0
CMS1_k127_5951010_12 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000003006 172.0
CMS1_k127_5951010_13 Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000000000003087 135.0
CMS1_k127_5951010_14 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.000000000000000000000000000001505 123.0
CMS1_k127_5951010_15 Flavodoxin - - - 0.000000000000000000000005645 106.0
CMS1_k127_5951010_16 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000001696 104.0
CMS1_k127_5951010_17 ThiS family K03636 - - 0.00000000000000000002316 94.0
CMS1_k127_5951010_18 - - - - 0.0000000000002344 70.0
CMS1_k127_5951010_2 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 500.0
CMS1_k127_5951010_3 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 456.0
CMS1_k127_5951010_4 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 386.0
CMS1_k127_5951010_5 Sulfide dehydrogenase (Flavoprotein) subunit SudB K00528,K02823 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 378.0
CMS1_k127_5951010_6 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 286.0
CMS1_k127_5951010_7 Eukaryotic-type carbonic anhydrase K01674 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000001335 218.0
CMS1_k127_5951010_8 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.00000000000000000000000000000000000000000000000000000002239 203.0
CMS1_k127_5951010_9 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.0000000000000000000000000000000000000000000000000000006692 200.0
CMS1_k127_602302_0 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000002191 186.0
CMS1_k127_602302_1 - - - - 0.0000000000000000000000003253 112.0
CMS1_k127_602302_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000003901 72.0
CMS1_k127_6029915_0 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003659 261.0
CMS1_k127_6029915_1 Activator of Hsp90 ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000183 238.0
CMS1_k127_6029915_2 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000001083 198.0
CMS1_k127_6029915_3 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000000000000005987 181.0
CMS1_k127_6029915_4 Protein of unknown function (DUF4013) - - - 0.00000000000000000000000000000000000000000006102 169.0
CMS1_k127_6029915_5 Transposase, IS605 OrfB family - - - 0.0000237 54.0
CMS1_k127_6146726_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 517.0
CMS1_k127_6146726_1 Ribonuclease III family - - - 0.0000000000000000000000000003684 115.0
CMS1_k127_6146726_2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone - - - 0.00000000000000001406 84.0
CMS1_k127_6150320_0 AAA family ATPase, CDC48 subfamily K13525 - - 7.121e-317 985.0
CMS1_k127_6150320_1 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 3.135e-197 622.0
CMS1_k127_6150320_10 Belongs to the peptidase S16 family K06870 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 355.0
CMS1_k127_6150320_11 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000003874 250.0
CMS1_k127_6150320_12 CBS domain - - - 0.0000000000000003234 83.0
CMS1_k127_6150320_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000001362 70.0
CMS1_k127_6150320_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 3.368e-196 619.0
CMS1_k127_6150320_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 591.0
CMS1_k127_6150320_4 TIGRFAM UbiD family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 533.0
CMS1_k127_6150320_5 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 529.0
CMS1_k127_6150320_6 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 457.0
CMS1_k127_6150320_7 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 463.0
CMS1_k127_6150320_8 Domain of unknown function (DUF1743) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 390.0
CMS1_k127_6150320_9 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 363.0
CMS1_k127_6151080_0 Peptidase U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 462.0
CMS1_k127_6151080_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 444.0
CMS1_k127_6151080_10 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000005676 190.0
CMS1_k127_6151080_11 Family of unknown function (DUF5402) - - - 0.00000000000000000000000000000000000000001735 156.0
CMS1_k127_6151080_12 LUD domain - - - 0.0000000000000000000000000000000000000002263 157.0
CMS1_k127_6151080_13 Membrane protein, UPF0016 and UPF0016 domain-containing - - - 0.0000000000000000000000000000000000000005832 154.0
CMS1_k127_6151080_14 Nucleoside 2-deoxyribosyltransferase like K08728 - 2.4.2.6 0.00000000000000000000000000000000000005539 146.0
CMS1_k127_6151080_15 transcriptional - - - 0.00000000000000000000000000001483 119.0
CMS1_k127_6151080_16 - - - - 0.0000000000000000000001835 108.0
CMS1_k127_6151080_17 - - - - 0.0000000000000000001231 93.0
CMS1_k127_6151080_18 Protein of unknown function, DUF255 K04084 - 1.8.1.8 0.0000000000000000006948 92.0
CMS1_k127_6151080_19 Periplasmic copper-binding protein (NosD) K07218 - - 0.000000000000001459 87.0
CMS1_k127_6151080_2 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 433.0
CMS1_k127_6151080_20 response regulator, receiver - - - 0.00000006655 66.0
CMS1_k127_6151080_21 - - - - 0.0006363 46.0
CMS1_k127_6151080_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 355.0
CMS1_k127_6151080_4 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001091 239.0
CMS1_k127_6151080_5 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000001723 236.0
CMS1_k127_6151080_6 Histidine kinase A domain protein K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000002274 247.0
CMS1_k127_6151080_7 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000002376 229.0
CMS1_k127_6151080_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000003117 195.0
CMS1_k127_6151080_9 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000178 193.0
CMS1_k127_6226662_0 DUF72 domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002275 253.0
CMS1_k127_6226662_1 Protein of unknown function DUF72 - - - 0.000000000000000007273 94.0
CMS1_k127_6226662_2 exo-alpha-(2->6)-sialidase activity - - - 0.000002813 54.0
CMS1_k127_6226662_3 3-demethylubiquinone-9 3-methyltransferase - - - 0.0001393 44.0
CMS1_k127_623275_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 5.367e-198 627.0
CMS1_k127_623275_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 385.0
CMS1_k127_623275_10 Yip1 domain - - - 0.00000000000000000000004613 107.0
CMS1_k127_623275_11 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000000000001158 98.0
CMS1_k127_623275_12 Nitroreductase family - - - 0.000000000000000009535 85.0
CMS1_k127_623275_13 - - - - 0.00000000000000004585 89.0
CMS1_k127_623275_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 350.0
CMS1_k127_623275_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 334.0
CMS1_k127_623275_4 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 313.0
CMS1_k127_623275_5 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001815 284.0
CMS1_k127_623275_6 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006389 274.0
CMS1_k127_623275_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000002501 233.0
CMS1_k127_623275_8 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000000000000000009069 239.0
CMS1_k127_623275_9 - - - - 0.0000000000000000000000000732 114.0
CMS1_k127_63086_0 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 581.0
CMS1_k127_63086_1 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 548.0
CMS1_k127_63086_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 293.0
CMS1_k127_63086_3 Male sterility protein - - - 0.000255 47.0
CMS1_k127_736864_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 458.0
CMS1_k127_736864_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 343.0
CMS1_k127_736864_10 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000000000000006105 142.0
CMS1_k127_736864_11 Protein of unknown function DUF86 - - - 0.0000000000000000000000000871 111.0
CMS1_k127_736864_12 nucleotidyltransferase activity K07076 - - 0.000000000000001606 83.0
CMS1_k127_736864_13 PDGLE domain K02009 - - 0.0003012 52.0
CMS1_k127_736864_14 FR47-like protein - - - 0.0005777 48.0
CMS1_k127_736864_2 SMART Peptidase A22, presenilin signal peptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 318.0
CMS1_k127_736864_3 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 295.0
CMS1_k127_736864_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005036 278.0
CMS1_k127_736864_5 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007253 268.0
CMS1_k127_736864_6 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001295 250.0
CMS1_k127_736864_7 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000000000000000000000004205 229.0
CMS1_k127_736864_8 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000000000000000000000000007151 221.0
CMS1_k127_736864_9 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000005339 162.0
CMS1_k127_741672_0 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000306 234.0
CMS1_k127_741672_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000543 177.0
CMS1_k127_741672_2 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000004263 152.0
CMS1_k127_741672_3 Cytochrome c - - - 0.0000000007082 61.0
CMS1_k127_741672_4 electron transfer activity - - - 0.000000213 53.0
CMS1_k127_741672_5 cytochrome C peroxidase - - - 0.0006693 43.0
CMS1_k127_7556_0 acid binding OB-fold tRNA helicase-type K07463 - - 3.502e-282 883.0
CMS1_k127_7556_1 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 477.0
CMS1_k127_7556_10 4Fe-4S binding domain - - - 0.000000000000001868 78.0
CMS1_k127_7556_11 regulatory protein, arsR - - - 0.0000000117 68.0
CMS1_k127_7556_12 - - - - 0.00000001468 60.0
CMS1_k127_7556_13 COG1938 Archaeal enzymes of ATP-grasp superfamily K06869 - - 0.000005616 57.0
CMS1_k127_7556_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 459.0
CMS1_k127_7556_3 Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 365.0
CMS1_k127_7556_4 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000557 237.0
CMS1_k127_7556_5 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000000001936 232.0
CMS1_k127_7556_6 PFAM Phosphatidylglycerophosphatase A - - - 0.0000000000000000000000000000000000000000000000000000000000000005613 225.0
CMS1_k127_7556_7 Non-histone chromosomal protein MC1 - - - 0.00000000000000000000000000000000000000006092 152.0
CMS1_k127_7556_8 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03387 - 1.8.1.9 0.0000000000000000000000000000000000021 145.0
CMS1_k127_7556_9 TIGRFAM PAS sensor protein - - - 0.0000000000000000000000000000000001485 152.0
CMS1_k127_879976_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 1.6e-257 807.0
CMS1_k127_879976_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 518.0
CMS1_k127_879976_2 PFAM TatD-related deoxyribonuclease K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 339.0
CMS1_k127_879976_3 - - - - 0.0000000000000000000000000000000004264 138.0
CMS1_k127_879976_4 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000003771 124.0
CMS1_k127_879976_5 nucleic acid-binding protein, contains PIN domain K07065 - - 0.0000000000000000000000003532 109.0
CMS1_k127_8851_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003893 289.0
CMS1_k127_8851_1 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000000000000000000009552 138.0
CMS1_k127_8851_2 Iron-sulphur cluster biosynthesis K15724 - - 0.00000000000000000000000000006312 119.0
CMS1_k127_8851_3 Radical SAM superfamily - - - 0.00000001821 61.0
CMS1_k127_907164_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01531,K01535 - 3.6.3.2,3.6.3.6 0.0 1133.0
CMS1_k127_907164_1 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 3.979e-290 903.0
CMS1_k127_907164_10 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 312.0
CMS1_k127_907164_11 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 305.0
CMS1_k127_907164_12 Acetyltransferase (GNAT) family K21935 - 2.3.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000155 285.0
CMS1_k127_907164_13 PFAM MscS Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002078 281.0
CMS1_k127_907164_14 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000004314 235.0
CMS1_k127_907164_15 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000001124 220.0
CMS1_k127_907164_16 conserved protein, contains double-stranded beta-helix domain K00450,K06720 - 1.13.11.4,4.2.1.108 0.0000000000000000000000002181 109.0
CMS1_k127_907164_17 Cytochrome C oxidase, cbb3-type, subunit III K02275 - 1.9.3.1 0.00000000000000000000002277 104.0
CMS1_k127_907164_18 COG1119 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA K02013 - 3.6.3.34 0.0000000000000000000001426 98.0
CMS1_k127_907164_19 - - - - 0.0000000000000000000002858 98.0
CMS1_k127_907164_2 Lysine-2,3-aminomutase K01843 - 5.4.3.2 6.252e-232 723.0
CMS1_k127_907164_20 Protein of unknown function (DUF473) K09135 - - 0.000000000000000000003433 98.0
CMS1_k127_907164_21 Trypsin - - - 0.000000000000000004119 87.0
CMS1_k127_907164_22 PFAM Transposase - - - 0.0000000000000000427 85.0
CMS1_k127_907164_23 PFAM MscS Mechanosensitive ion channel K03442,K22044 - - 0.00000004596 63.0
CMS1_k127_907164_24 Domain in cystathionine beta-synthase and other proteins. - - - 0.00003175 51.0
CMS1_k127_907164_25 TIGRFAM Glutaredoxin-like domain protein - - - 0.0004132 44.0
CMS1_k127_907164_3 4Fe-4S single cluster domain K01843 - 5.4.3.2 9.268e-230 726.0
CMS1_k127_907164_4 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006599 585.0
CMS1_k127_907164_5 COG0531 Amino acid transporters - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 581.0
CMS1_k127_907164_6 Chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 558.0
CMS1_k127_907164_7 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 518.0
CMS1_k127_907164_8 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 493.0
CMS1_k127_907164_9 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 385.0
CMS1_k127_910195_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 533.0
CMS1_k127_910195_1 TIGRFAM small GTP-binding protein K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 389.0
CMS1_k127_910195_10 Plasmid pRiA4b ORF-3-like protein - - - 0.00000000000000000001398 103.0
CMS1_k127_910195_11 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000547 95.0
CMS1_k127_910195_2 extracellular solute-binding protein, family 1 K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003075 271.0
CMS1_k127_910195_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000006191 259.0
CMS1_k127_910195_4 abc transporter atp-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000001422 246.0
CMS1_k127_910195_5 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005573 253.0
CMS1_k127_910195_6 ABC-type tungstate transport system, periplasmic component K05773 - - 0.0000000000000000000000000000000000000000000000000000001201 203.0
CMS1_k127_910195_7 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000002023 188.0
CMS1_k127_910195_8 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000000000000000000000000000003059 180.0
CMS1_k127_910195_9 negative regulation of cell growth - - - 0.000000000000000000000000000000000000000001059 169.0
CMS1_k127_917864_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 6.837e-243 766.0
CMS1_k127_917864_1 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 610.0
CMS1_k127_917864_10 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009278 273.0
CMS1_k127_917864_11 PFAM TfuA domain protein, core - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001152 257.0
CMS1_k127_917864_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001226 259.0
CMS1_k127_917864_13 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.0000000000000000000000000000000000000000000000000002563 188.0
CMS1_k127_917864_14 - - - - 0.000000000000000000000000000000000000000000000000003793 192.0
CMS1_k127_917864_15 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000000000000000000000001202 178.0
CMS1_k127_917864_16 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000006665 142.0
CMS1_k127_917864_18 PFAM Methyltransferase type 11 - - - 0.000001086 57.0
CMS1_k127_917864_2 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 513.0
CMS1_k127_917864_3 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 483.0
CMS1_k127_917864_4 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 376.0
CMS1_k127_917864_5 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 364.0
CMS1_k127_917864_6 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 337.0
CMS1_k127_917864_7 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 344.0
CMS1_k127_917864_8 PFAM glutamate synthase alpha subunit K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 315.0
CMS1_k127_917864_9 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000972 286.0
CMS1_k127_950341_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 500.0
CMS1_k127_950341_1 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 461.0
CMS1_k127_950341_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 336.0
CMS1_k127_950341_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000985 192.0
CMS1_k127_950341_4 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000001253 144.0
CMS1_k127_958425_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 2.954e-219 686.0
CMS1_k127_958425_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2e-211 663.0
CMS1_k127_958425_10 Fe-S cluster K04488 - - 0.0000000000000000000000000000000000000000000000000000000131 215.0
CMS1_k127_958425_11 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000000000000000000000000000002468 162.0
CMS1_k127_958425_12 protein conserved in archaea - - - 0.00000000000000000000000000000000000002633 156.0
CMS1_k127_958425_13 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000001196 140.0
CMS1_k127_958425_14 Probable transposase K07496 - - 0.0000000000000000000000007601 109.0
CMS1_k127_958425_15 iron ion binding - - - 0.00000000000006908 72.0
CMS1_k127_958425_16 - - - - 0.0000000008559 69.0
CMS1_k127_958425_17 - - - - 0.000002231 52.0
CMS1_k127_958425_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 539.0
CMS1_k127_958425_3 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 452.0
CMS1_k127_958425_4 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 441.0
CMS1_k127_958425_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 436.0
CMS1_k127_958425_6 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 391.0
CMS1_k127_958425_7 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 328.0
CMS1_k127_958425_8 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000224 249.0
CMS1_k127_958425_9 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000046 232.0
CMS1_k127_963982_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 7.612e-301 932.0
CMS1_k127_963982_1 MCP methyltransferase, CheR-type K13924 - 2.1.1.80,3.1.1.61 2.706e-300 946.0
CMS1_k127_963982_10 Iron permease FTR1 family K07243 - - 0.0000000000000000000000000000000000000000000000000000000000000007494 228.0
CMS1_k127_963982_11 Conserved hypothetical protein 95 K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000003017 206.0
CMS1_k127_963982_12 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000001333 185.0
CMS1_k127_963982_13 FeoA K03709 - - 0.0000000000000000000000000000000000000000000000003259 183.0
CMS1_k127_963982_14 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000004848 157.0
CMS1_k127_963982_15 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000002141 140.0
CMS1_k127_963982_16 cheY-homologous receiver domain K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000000000000000003379 126.0
CMS1_k127_963982_17 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000004241 116.0
CMS1_k127_963982_18 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.000000009335 58.0
CMS1_k127_963982_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 482.0
CMS1_k127_963982_3 Ferrous iron transport protein B K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 478.0
CMS1_k127_963982_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 333.0
CMS1_k127_963982_5 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 323.0
CMS1_k127_963982_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 332.0
CMS1_k127_963982_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 308.0
CMS1_k127_963982_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 302.0
CMS1_k127_963982_9 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000324 239.0
CMS1_k127_98660_0 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 3.367e-201 634.0
CMS1_k127_98660_1 aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 567.0
CMS1_k127_98660_10 Transcriptional regulator, TrmB - - - 0.0000000000000000000000006239 108.0
CMS1_k127_98660_11 Rubredoxin - - - 0.0000000000000000000001548 97.0
CMS1_k127_98660_12 Winged helix-turn-helix DNA-binding - - - 0.000000000000000005993 87.0
CMS1_k127_98660_14 Family of unknown function (DUF5350) - - - 0.0000000000002413 72.0
CMS1_k127_98660_15 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000002734 73.0
CMS1_k127_98660_16 Protein of unknown function (DUF1295) - - - 0.0000003879 63.0
CMS1_k127_98660_2 YHS domain K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 505.0
CMS1_k127_98660_3 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 467.0
CMS1_k127_98660_4 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000238 253.0
CMS1_k127_98660_5 PBS lyase HEAT domain protein repeat-containing protein K22221 - - 0.0000000000000000000000000000000000000000000000000000000461 214.0
CMS1_k127_98660_6 PFAM peptidase - - - 0.00000000000000000000000000000000000000004173 160.0
CMS1_k127_98660_7 Domain present in carbohydrate binding proteins and sugar hydrolses - - - 0.000000000000000000000000000000000001415 156.0
CMS1_k127_98660_8 - - - - 0.000000000000000000000000000000003595 130.0
CMS1_k127_98660_9 Acid phosphatase homologues - - - 0.0000000000000000000000000001035 127.0