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Overview

ID MAG00351
Name CMS1_bin.3
Sample SMP0010
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanosarcinia
Order Methanosarcinales
Family Methanocomedenaceae
Genus
Species
Assembly information
Completeness (%) 89.54
Contamination (%) 0.59
GC content (%) 47.0
N50 (bp) 15,887
Genome size (bp) 1,823,559

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1812

Gene name Description KEGG GOs EC E-value Score Sequence
CMS1_k127_1002916_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 622.0
CMS1_k127_1002916_1 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000000000000000000000000000009616 207.0
CMS1_k127_1002916_2 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000003628 198.0
CMS1_k127_1002916_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000001537 190.0
CMS1_k127_1002916_4 - - - - 0.0000000000000000000000000000000000000000000000000004816 188.0
CMS1_k127_1002916_5 - - - - 0.00000000000005026 72.0
CMS1_k127_1021762_0 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 572.0
CMS1_k127_1021762_1 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 338.0
CMS1_k127_1021762_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000004758 79.0
CMS1_k127_1021762_2 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 326.0
CMS1_k127_1021762_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 298.0
CMS1_k127_1021762_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000006569 186.0
CMS1_k127_1021762_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000001353 183.0
CMS1_k127_1021762_6 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.00000000000000000000000000000000003216 139.0
CMS1_k127_1021762_7 Domain of unknown function DUF123 - - - 0.000000000000000000000000000000004157 134.0
CMS1_k127_1021762_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.00000000000000000000004293 99.0
CMS1_k127_1021762_9 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000002499 91.0
CMS1_k127_1021901_0 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 1.939e-224 709.0
CMS1_k127_1021901_1 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 552.0
CMS1_k127_1021901_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002848 289.0
CMS1_k127_1021901_11 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002113 266.0
CMS1_k127_1021901_12 ATP-grasp domain K06914 - 6.3.4.24 0.000000000000000000000000000000000000000000000000000000000000000000000005713 253.0
CMS1_k127_1021901_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000174 246.0
CMS1_k127_1021901_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004149 253.0
CMS1_k127_1021901_15 - K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000005105 251.0
CMS1_k127_1021901_16 FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000000000000000000000000000000000009885 208.0
CMS1_k127_1021901_17 Belongs to the SUI1 family K03113 - - 0.00000000000000000000000000000000000000000000003678 171.0
CMS1_k127_1021901_18 CDP-alcohol phosphatidyltransferase K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000001355 165.0
CMS1_k127_1021901_19 PFAM molydopterin dinucleotide-binding region K00203 - 1.2.7.12 0.000000000000000000000000000000000000000001518 159.0
CMS1_k127_1021901_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 481.0
CMS1_k127_1021901_20 - - - - 0.0000000000000000000000000000000000002302 150.0
CMS1_k127_1021901_21 Protein of unknown function (DUF356) K09727 - - 0.000000000000000000000000000001748 124.0
CMS1_k127_1021901_22 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000000003546 116.0
CMS1_k127_1021901_23 Transcriptional regulator K07108 - - 0.0000000000000000000000001015 111.0
CMS1_k127_1021901_24 Winged helix-turn-helix DNA-binding - - - 0.0000000000000000000000007718 106.0
CMS1_k127_1021901_25 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000002977 89.0
CMS1_k127_1021901_26 Roadblock LC7 family protein K07131 - - 0.000959 47.0
CMS1_k127_1021901_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 477.0
CMS1_k127_1021901_4 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 426.0
CMS1_k127_1021901_5 Domain of unknown function (DUF373) K08975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 353.0
CMS1_k127_1021901_6 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 326.0
CMS1_k127_1021901_7 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 297.0
CMS1_k127_1021901_8 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000284 287.0
CMS1_k127_1021901_9 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005797 282.0
CMS1_k127_1029919_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 534.0
CMS1_k127_1029919_1 COG0191 Fructose tagatose bisphosphate aldolase K01624,K08302 - 4.1.2.13,4.1.2.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 480.0
CMS1_k127_1029919_10 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000004046 107.0
CMS1_k127_1029919_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 448.0
CMS1_k127_1029919_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 292.0
CMS1_k127_1029919_4 Putative small multi-drug export protein - - - 0.000000000000000000000000000000000000000000000000000000000001163 214.0
CMS1_k127_1029919_5 Protein of unknown function (DUF2961) K14109 - - 0.000000000000000000000000000000000000000000000000000001632 205.0
CMS1_k127_1029919_6 membrane-associated protein domain - - - 0.0000000000000000000000000000000000001914 153.0
CMS1_k127_1029919_7 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000001447 132.0
CMS1_k127_1029919_8 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000007243 126.0
CMS1_k127_1029919_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000386 115.0
CMS1_k127_106030_0 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 462.0
CMS1_k127_106030_1 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 424.0
CMS1_k127_106030_10 - - - - 0.0000000009644 66.0
CMS1_k127_106030_11 - - - - 0.0000006902 59.0
CMS1_k127_106030_2 PFAM GTP-binding protein HSR1-related K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 342.0
CMS1_k127_106030_3 Phosphate uptake regulator, PhoU - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001432 271.0
CMS1_k127_106030_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000001214 179.0
CMS1_k127_106030_5 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.0000000000000000000000000000000000000000006428 160.0
CMS1_k127_106030_6 Zn-ribbon containing protein K07163 - - 0.000000000000000000000000000000000000009513 149.0
CMS1_k127_106030_7 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000004578 102.0
CMS1_k127_106030_8 Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000001672 83.0
CMS1_k127_106030_9 - - - - 0.0000000000000003635 84.0
CMS1_k127_1060427_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0 1119.0
CMS1_k127_1060427_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1019.0
CMS1_k127_1060427_10 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000000000000000000000000000000003344 187.0
CMS1_k127_1060427_11 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000007306 165.0
CMS1_k127_1060427_12 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000004104 129.0
CMS1_k127_1060427_13 - - - - 0.000000000000000000000001833 111.0
CMS1_k127_1060427_14 Heavy-metal-associated domain K07213 - - 0.00000000000006255 74.0
CMS1_k127_1060427_15 - K08982 - - 0.0000000000002182 73.0
CMS1_k127_1060427_16 Protein of unknown function, DUF255 - - - 0.0000000006494 66.0
CMS1_k127_1060427_17 subunit of a heme lyase K02200 - - 0.0000007867 57.0
CMS1_k127_1060427_18 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0001924 49.0
CMS1_k127_1060427_2 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 541.0
CMS1_k127_1060427_3 PFAM chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001274 276.0
CMS1_k127_1060427_4 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000774 256.0
CMS1_k127_1060427_5 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000008023 251.0
CMS1_k127_1060427_6 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000000000000000006042 220.0
CMS1_k127_1060427_7 Cytochrome c K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000003882 200.0
CMS1_k127_1060427_8 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000001345 194.0
CMS1_k127_1060427_9 ABC-type tungstate transport system, periplasmic component K05773 - - 0.00000000000000000000000000000000000000000000000000001818 196.0
CMS1_k127_1066724_0 PFAM Aldehyde dehydrogenase K22187 - - 5.914e-250 779.0
CMS1_k127_1066724_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 5.997e-211 668.0
CMS1_k127_1066724_10 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000001613 211.0
CMS1_k127_1066724_11 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000756 66.0
CMS1_k127_1066724_2 Aminotransferase class-III K00823,K00836 - 2.6.1.19,2.6.1.76 7.069e-203 639.0
CMS1_k127_1066724_3 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 516.0
CMS1_k127_1066724_4 Fumarase C C-terminus K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 474.0
CMS1_k127_1066724_5 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 453.0
CMS1_k127_1066724_6 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 422.0
CMS1_k127_1066724_7 Belongs to the UPF0280 family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006206 273.0
CMS1_k127_1066724_8 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000007563 226.0
CMS1_k127_1066724_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000005206 207.0
CMS1_k127_1095914_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 462.0
CMS1_k127_1095914_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 351.0
CMS1_k127_1095914_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 344.0
CMS1_k127_1095914_3 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006273 331.0
CMS1_k127_1095914_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000009174 186.0
CMS1_k127_1095914_5 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000054 133.0
CMS1_k127_1095914_6 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.000000000000000000004211 96.0
CMS1_k127_1095914_7 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000002364 91.0
CMS1_k127_1095914_8 4Fe-4S dicluster domain - - - 0.0000000000000000000355 91.0
CMS1_k127_1095914_9 - - - - 0.000006772 52.0
CMS1_k127_1106062_0 PFAM type II secretion system protein E K07332 - - 1.366e-232 746.0
CMS1_k127_1106062_1 type II secretion system protein K07333 - - 3.821e-222 708.0
CMS1_k127_1106062_2 TIGRFAM cell division ATPase MinD K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 359.0
CMS1_k127_1106062_3 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 306.0
CMS1_k127_1106062_4 - - - - 0.000000005181 59.0
CMS1_k127_1106062_5 von Willebrand factor, type A - - - 0.0000004604 56.0
CMS1_k127_1144372_0 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001377 276.0
CMS1_k127_1144372_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002708 271.0
CMS1_k127_1144372_2 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000002023 267.0
CMS1_k127_1144372_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000002469 199.0
CMS1_k127_1156009_0 CoB--CoM heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 415.0
CMS1_k127_1156009_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 312.0
CMS1_k127_1156009_2 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000005422 188.0
CMS1_k127_1156009_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000287 78.0
CMS1_k127_1178990_0 NAD(P)H dehydrogenase (quinone) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 544.0
CMS1_k127_1178990_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000007745 219.0
CMS1_k127_1178990_2 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000000000000000000000001228 197.0
CMS1_k127_1178990_3 COG1520 FOG WD40-like repeat K17713 - - 0.00000000003309 74.0
CMS1_k127_1295850_0 lipoprotein transporter activity K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009733 243.0
CMS1_k127_1295850_1 lipoprotein localization to outer membrane K09808 - - 0.0000000000000000000000002268 119.0
CMS1_k127_1295850_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000001674 117.0
CMS1_k127_1296820_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1187.0
CMS1_k127_1296820_1 PHP C-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 446.0
CMS1_k127_1296820_2 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 345.0
CMS1_k127_1296820_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001445 255.0
CMS1_k127_1296820_4 COG0500 SAM-dependent methyltransferases K17462 - - 0.000000000000000000000000000000000000000000000000000000000000001154 226.0
CMS1_k127_1296820_5 COG3634 Alkyl hydroperoxide reductase, large subunit - - - 0.00000000000000000002298 94.0
CMS1_k127_1296820_6 - K21471 - - 0.0000003492 62.0
CMS1_k127_1296820_7 membrane-associated protein domain - - - 0.0000004406 61.0
CMS1_k127_1301243_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 9.815e-298 925.0
CMS1_k127_1301243_1 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 1.098e-236 743.0
CMS1_k127_1301243_10 Acetyltransferase (GNAT) domain K21935 - 2.3.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000009693 268.0
CMS1_k127_1301243_11 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000001057 229.0
CMS1_k127_1301243_12 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.00000000000000000000000000000000000000000002506 164.0
CMS1_k127_1301243_13 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000001885 165.0
CMS1_k127_1301243_14 - - - - 0.0000000000000000000000000000005829 124.0
CMS1_k127_1301243_15 Iron-sulphur cluster biosynthesis K15724 - - 0.00000000000000000000000006723 109.0
CMS1_k127_1301243_16 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.0000000000003586 80.0
CMS1_k127_1301243_18 Protein of unknown function (DUF3795) - - - 0.000000184 56.0
CMS1_k127_1301243_2 Lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 3.445e-221 691.0
CMS1_k127_1301243_3 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 571.0
CMS1_k127_1301243_4 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 505.0
CMS1_k127_1301243_5 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 490.0
CMS1_k127_1301243_6 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 417.0
CMS1_k127_1301243_7 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K02588,K21610 - 1.18.6.1,6.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 385.0
CMS1_k127_1301243_8 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 337.0
CMS1_k127_1301243_9 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 323.0
CMS1_k127_137122_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 7.969e-282 894.0
CMS1_k127_137122_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009186 436.0
CMS1_k127_137122_2 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 287.0
CMS1_k127_137122_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000002781 263.0
CMS1_k127_137122_4 carbon monoxide dehydrogenase K09386 - - 0.00003453 51.0
CMS1_k127_1387398_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 501.0
CMS1_k127_1387398_1 Male sterility protein K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 495.0
CMS1_k127_1387398_10 - - - - 0.0000000000000001002 90.0
CMS1_k127_1387398_11 Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import K12261,K13342 GO:0000268,GO:0003674,GO:0005048,GO:0005052,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005778,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006635,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015031,GO:0015833,GO:0015919,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016558,GO:0016560,GO:0017038,GO:0019395,GO:0019752,GO:0030258,GO:0030674,GO:0031090,GO:0031903,GO:0032787,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034440,GO:0034613,GO:0042277,GO:0042579,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043574,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0044743,GO:0045184,GO:0046395,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0055114,GO:0060090,GO:0065002,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071806,GO:0071840,GO:0072329,GO:0072594,GO:0072662,GO:0072663,GO:0098588,GO:0098805,GO:1901575,GO:1990351,GO:1990415,GO:1990429 - 0.00003383 49.0
CMS1_k127_1387398_2 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 471.0
CMS1_k127_1387398_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 389.0
CMS1_k127_1387398_4 Polysaccharide biosynthesis protein K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 384.0
CMS1_k127_1387398_5 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 320.0
CMS1_k127_1387398_6 WxcM-like, C-terminal K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 299.0
CMS1_k127_1387398_7 Glycosyl transferase family group 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001569 280.0
CMS1_k127_1387398_8 PFAM Glycosyl transferase family 2 K12992 - - 0.00000000000000000000000000000000000000000000000000827 192.0
CMS1_k127_1387398_9 - - - - 0.000000000000000002706 93.0
CMS1_k127_1432438_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 6.853e-277 863.0
CMS1_k127_1432438_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 6.025e-222 699.0
CMS1_k127_1432438_10 Pfam:DUF137 K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000118 282.0
CMS1_k127_1432438_11 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000373 277.0
CMS1_k127_1432438_12 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004803 257.0
CMS1_k127_1432438_13 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000057 237.0
CMS1_k127_1432438_14 PFAM methyltransferase small K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000006973 184.0
CMS1_k127_1432438_15 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000302 177.0
CMS1_k127_1432438_16 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.0000000000000000000000000000000000003779 141.0
CMS1_k127_1432438_17 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000000000000000000000000216 123.0
CMS1_k127_1432438_18 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000001179 113.0
CMS1_k127_1432438_19 Protein of unknown function (DUF1699) - - - 0.00000000000000000008022 93.0
CMS1_k127_1432438_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.321e-209 659.0
CMS1_k127_1432438_20 JAB/MPN domain - - - 0.0000000000000001156 85.0
CMS1_k127_1432438_21 PFAM Thiolase K00626 - 2.3.1.9 0.000000001026 59.0
CMS1_k127_1432438_3 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 571.0
CMS1_k127_1432438_4 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 565.0
CMS1_k127_1432438_5 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 509.0
CMS1_k127_1432438_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 465.0
CMS1_k127_1432438_7 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 441.0
CMS1_k127_1432438_8 Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 418.0
CMS1_k127_1432438_9 Helix-turn-helix domain protein K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 293.0
CMS1_k127_1440160_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.409e-302 941.0
CMS1_k127_1440160_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 3.405e-256 799.0
CMS1_k127_1440160_10 Glycine cleavage system H protein K02437 - - 0.00000000000000000000000000003538 121.0
CMS1_k127_1440160_11 Protein of unknown function (DUF357) K09728 - - 0.0000000000000000000000000004646 115.0
CMS1_k127_1440160_12 heme binding K08642 - - 0.00000000000000000000000002179 120.0
CMS1_k127_1440160_13 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000001826 103.0
CMS1_k127_1440160_15 nucleic acid binding OB-fold tRNA helicase-type - - - 0.00000000000000000001993 95.0
CMS1_k127_1440160_16 - - - - 0.00000000000000004746 84.0
CMS1_k127_1440160_17 Radical SAM domain protein K01012 - 2.8.1.6 0.0000006516 51.0
CMS1_k127_1440160_18 cell wall organization - - - 0.000005192 58.0
CMS1_k127_1440160_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 423.0
CMS1_k127_1440160_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 427.0
CMS1_k127_1440160_4 SMART AAA ATPase K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 411.0
CMS1_k127_1440160_5 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 349.0
CMS1_k127_1440160_6 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 332.0
CMS1_k127_1440160_7 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.000000000000000000000000000000000000000000000000000003941 202.0
CMS1_k127_1440160_8 Belongs to the UPF0212 family K09731 - - 0.000000000000000000000000000000000000000000000000001681 184.0
CMS1_k127_1440160_9 AAA domain (dynein-related subfamily) K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000001006 177.0
CMS1_k127_1629581_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4.283e-311 971.0
CMS1_k127_1629581_1 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 501.0
CMS1_k127_1629581_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000003082 223.0
CMS1_k127_1629581_11 nitroreductase - - - 0.000000000000000000000000000000000000000000000000000776 188.0
CMS1_k127_1629581_12 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000002406 174.0
CMS1_k127_1629581_13 Helix-turn-helix domain protein K03627 - - 0.000000000000000000000000000000000000000000001923 169.0
CMS1_k127_1629581_14 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000000000000002638 156.0
CMS1_k127_1629581_15 Conserved protein - - - 0.00000000000000000000000000000000000006186 158.0
CMS1_k127_1629581_16 radical SAM domain protein - - - 0.000000000000000000000000000000000002855 154.0
CMS1_k127_1629581_17 Protein of unknown function (DUF356) K09727 - - 0.0000000000000000000000000000000000283 138.0
CMS1_k127_1629581_18 Roadblock LC7 family protein K07131 - - 0.0000000000000000000004056 100.0
CMS1_k127_1629581_19 Pfam:DUF1628 - - - 0.000000000000000000108 91.0
CMS1_k127_1629581_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 490.0
CMS1_k127_1629581_20 - - - - 0.00000000000000002915 85.0
CMS1_k127_1629581_21 - - - - 0.0000000000000002236 87.0
CMS1_k127_1629581_22 Family of unknown function (DUF5371) - - - 0.0000000000000006129 80.0
CMS1_k127_1629581_23 but it may be involved in stabilization of the trimeric complex - - - 0.00000000000003782 73.0
CMS1_k127_1629581_3 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 400.0
CMS1_k127_1629581_4 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 366.0
CMS1_k127_1629581_5 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 335.0
CMS1_k127_1629581_6 SMART Peptidase A22, presenilin signal peptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 311.0
CMS1_k127_1629581_7 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001649 258.0
CMS1_k127_1629581_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000005583 252.0
CMS1_k127_1629581_9 RIO1 family K08851 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000009361 230.0
CMS1_k127_1802555_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 598.0
CMS1_k127_1802555_1 PFAM AIR synthase related protein K07388 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 589.0
CMS1_k127_1802555_10 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000009558 130.0
CMS1_k127_1802555_11 parallel beta-helix repeat K03671 - - 0.00000000000000000000000001174 115.0
CMS1_k127_1802555_12 COG2834 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000005306 96.0
CMS1_k127_1802555_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 392.0
CMS1_k127_1802555_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 373.0
CMS1_k127_1802555_4 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 332.0
CMS1_k127_1802555_5 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000009615 228.0
CMS1_k127_1802555_6 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000000002182 228.0
CMS1_k127_1802555_7 Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000001585 210.0
CMS1_k127_1802555_8 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000001871 204.0
CMS1_k127_1802555_9 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000009397 190.0
CMS1_k127_1803918_0 PFAM SufBD protein K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 327.0
CMS1_k127_1803918_1 PFAM ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003308 276.0
CMS1_k127_1803918_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000000000000001864 176.0
CMS1_k127_1803918_3 acetyltransferase K09994 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019634,GO:0019637,GO:0033051,GO:0044237,GO:0044424,GO:0044464,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000007135 153.0
CMS1_k127_1803918_4 Nitroreductase family - - - 0.00000000000000000000000000008641 123.0
CMS1_k127_1803918_5 Putative zinc ribbon domain - - - 0.0000000000000005323 79.0
CMS1_k127_1803918_6 Nucleotidyltransferase domain K07075 - - 0.00000000000000639 75.0
CMS1_k127_1814835_0 TIGRFAM nitrogenase molybdenum-iron protein alpha chain K02586 - 1.18.6.1 1.784e-284 881.0
CMS1_k127_1814835_1 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 1.359e-237 740.0
CMS1_k127_1814835_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 394.0
CMS1_k127_1814835_11 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006588 373.0
CMS1_k127_1814835_12 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 318.0
CMS1_k127_1814835_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 314.0
CMS1_k127_1814835_14 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 286.0
CMS1_k127_1814835_15 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002264 277.0
CMS1_k127_1814835_16 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003603 279.0
CMS1_k127_1814835_17 Molybdate transporter of MFS superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002397 260.0
CMS1_k127_1814835_18 ZPR1-related zinc finger protein K06874 - - 0.000000000000000000000000000000000000000000000000000000000000000000008808 240.0
CMS1_k127_1814835_19 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000001703 208.0
CMS1_k127_1814835_2 Belongs to the NifD NifK NifE NifN family K02587 - - 2.12e-227 711.0
CMS1_k127_1814835_20 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000004073 204.0
CMS1_k127_1814835_21 TIGRFAM cell division ATPase MinD K03609 - - 0.000000000000000000000000000000000000000000000000000000000445 212.0
CMS1_k127_1814835_22 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000000005297 211.0
CMS1_k127_1814835_23 Belongs to the P(II) protein family K02590 - - 0.000000000000000000000000000000000000000000000000000002153 195.0
CMS1_k127_1814835_24 Protein of unknown function (DUF98) - - - 0.00000000000000000000000000000000000000000000000000002423 192.0
CMS1_k127_1814835_25 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000008088 201.0
CMS1_k127_1814835_26 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000552 173.0
CMS1_k127_1814835_27 Nitrogen regulatory protein P-II K02589 - - 0.0000000000000000000000000000000000000000000009989 167.0
CMS1_k127_1814835_28 PFAM PUA domain containing protein K07575 - - 0.0000000000000000000000000000000000000000000607 164.0
CMS1_k127_1814835_29 Pfam:DUF552 K09152 - - 0.0000000000000000000000000000000000000000005865 160.0
CMS1_k127_1814835_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 4.878e-217 685.0
CMS1_k127_1814835_30 toxin activity - - - 0.00000000000000000000000000000000004456 143.0
CMS1_k127_1814835_31 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.0000000000000000000000000000047 123.0
CMS1_k127_1814835_32 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.0000000000000000000000000000484 117.0
CMS1_k127_1814835_33 - - - - 0.00000000000000000000000000007318 118.0
CMS1_k127_1814835_34 - - - - 0.000000000000000000000000001134 119.0
CMS1_k127_1814835_35 Belongs to the UPF0305 family - - - 0.00000000000000000000000005085 114.0
CMS1_k127_1814835_36 binds to the 23S rRNA K02922 - - 0.00000000000000000000006852 98.0
CMS1_k127_1814835_37 Alternative locus ID K03789 - 2.3.1.128 0.000000000000000000004161 103.0
CMS1_k127_1814835_38 metallopeptidase activity - - - 0.0000000000002643 83.0
CMS1_k127_1814835_39 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0000000000004387 71.0
CMS1_k127_1814835_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.876e-211 665.0
CMS1_k127_1814835_40 - - - - 0.0000000000007279 76.0
CMS1_k127_1814835_41 - - - - 0.000000000341 74.0
CMS1_k127_1814835_42 - - - - 0.000000003351 58.0
CMS1_k127_1814835_43 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.00000002759 59.0
CMS1_k127_1814835_44 membrane - - - 0.0000004717 58.0
CMS1_k127_1814835_45 toxin activity - - - 0.00000113 52.0
CMS1_k127_1814835_46 Hemerythrin HHE cation binding domain protein - - - 0.0003087 50.0
CMS1_k127_1814835_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 3.995e-198 628.0
CMS1_k127_1814835_6 Belongs to the aspartokinase family K00928 - 2.7.2.4 3.081e-195 618.0
CMS1_k127_1814835_7 Belongs to the NifD NifK NifE NifN family K02592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 596.0
CMS1_k127_1814835_8 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 507.0
CMS1_k127_1814835_9 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 476.0
CMS1_k127_1819429_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 511.0
CMS1_k127_1819429_1 coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K00125 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008823 432.0
CMS1_k127_1819429_2 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000009139 209.0
CMS1_k127_1819429_3 - - - - 0.000000000000000000000000000002069 137.0
CMS1_k127_1819429_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000008713 85.0
CMS1_k127_1819429_6 PspC domain - - - 0.0000000000000004033 84.0
CMS1_k127_1819429_7 Pentapeptide repeats (9 copies) - - - 0.00001384 55.0
CMS1_k127_1848873_0 AAA domain K03657 - 3.6.4.12 2.466e-203 671.0
CMS1_k127_1848873_1 Putative exonuclease SbcCD, C subunit K03546 GO:0000014,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576,GO:1990238 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002573 297.0
CMS1_k127_1848873_2 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000007559 243.0
CMS1_k127_1848873_3 PFAM conserved K07027 - - 0.000000000000000000000000000000000000000000001323 173.0
CMS1_k127_1848873_4 4 iron, 4 sulfur cluster binding K11260 - - 0.0000000000000001508 81.0
CMS1_k127_1867403_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 602.0
CMS1_k127_1867403_1 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 526.0
CMS1_k127_1867403_2 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004331 260.0
CMS1_k127_1867403_3 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000000000000001423 230.0
CMS1_k127_1867403_4 Sugar-specific transcriptional regulator TrmB K07721 - - 0.0000000000000000000000000000000000781 135.0
CMS1_k127_1867403_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000002186 100.0
CMS1_k127_1867403_6 - - - - 0.0000000000009162 72.0
CMS1_k127_1867403_7 - - - - 0.00000003413 61.0
CMS1_k127_1867403_8 PFAM 4-vinyl reductase, 4VR K07013 - - 0.0000001011 60.0
CMS1_k127_1867403_9 Belongs to the sulfur carrier protein TusA family - - - 0.0000001454 55.0
CMS1_k127_19280_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 1.894e-317 987.0
CMS1_k127_19280_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 552.0
CMS1_k127_19280_2 PFAM regulatory protein, ArsR K07721 - - 0.00000000000000000000000000000000005444 142.0
CMS1_k127_19280_3 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000000000000004487 128.0
CMS1_k127_19280_4 Transmembrane secretion effector - - - 0.000000000000000001123 93.0
CMS1_k127_1962957_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.2e-224 701.0
CMS1_k127_1962957_1 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 535.0
CMS1_k127_1962957_10 - - - - 0.0000000000000000002065 95.0
CMS1_k127_1962957_11 - - - - 0.000000000000000008174 94.0
CMS1_k127_1962957_12 B-block binding subunit of TFIIIC - - - 0.000000000000000009336 88.0
CMS1_k127_1962957_13 - - - - 0.00000000000000003665 89.0
CMS1_k127_1962957_14 - - - - 0.0000000000001183 81.0
CMS1_k127_1962957_15 - - - - 0.0000000000002708 79.0
CMS1_k127_1962957_16 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.00000001084 67.0
CMS1_k127_1962957_17 Cupin domain - - - 0.0000002606 56.0
CMS1_k127_1962957_18 Mycolic acid cyclopropane synthetase K00559 - 2.1.1.41 0.00003173 55.0
CMS1_k127_1962957_2 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 312.0
CMS1_k127_1962957_3 Thermophilic metalloprotease (M29) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000784 276.0
CMS1_k127_1962957_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002259 276.0
CMS1_k127_1962957_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.00000000000000000000000000000000000000000000000000000000000000000001186 243.0
CMS1_k127_1962957_6 Uncharacterised protein family UPF0058 - - - 0.000000000000000000000000000001369 123.0
CMS1_k127_1962957_7 - - - - 0.000000000000000000000000473 105.0
CMS1_k127_1962957_8 PFAM Like-Sm ribonucleoprotein, core - - - 0.000000000000000000000006456 102.0
CMS1_k127_1962957_9 PFAM Peptidase S24 S26A S26B, conserved region K13280 - 3.4.21.89 0.000000000000000000002603 102.0
CMS1_k127_1991644_0 Chemotaxis protein CheA K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 540.0
CMS1_k127_1991644_1 3-beta hydroxysteroid dehydrogenase/isomerase family K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 453.0
CMS1_k127_1991644_10 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000003027 212.0
CMS1_k127_1991644_11 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000004243 207.0
CMS1_k127_1991644_12 Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000593 192.0
CMS1_k127_1991644_13 COG1668 ABC-type Na efflux pump, permease component - - - 0.00000000000000000000000000000000000000000000001409 184.0
CMS1_k127_1991644_14 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000001577 176.0
CMS1_k127_1991644_15 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000664 159.0
CMS1_k127_1991644_16 response regulator K03413 - - 0.00000000000000000000000000000000000003249 146.0
CMS1_k127_1991644_17 PFAM Adenylate cyclase K05873 GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 4.6.1.1 0.00000000000000000000000000000000003617 140.0
CMS1_k127_1991644_18 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.000000000000000000000000004557 118.0
CMS1_k127_1991644_19 protein conserved in archaea - - - 0.00000000000000000000000002484 114.0
CMS1_k127_1991644_2 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 441.0
CMS1_k127_1991644_20 Sulfurtransferase TusA K04085 - - 0.000000000000000000000002709 104.0
CMS1_k127_1991644_21 membrane - - - 0.00000000000000000000002317 107.0
CMS1_k127_1991644_23 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000005082 76.0
CMS1_k127_1991644_24 cheY-homologous receiver domain K07668 - - 0.000000000000196 79.0
CMS1_k127_1991644_25 - - - - 0.0000000004093 63.0
CMS1_k127_1991644_26 - - - - 0.00000002667 63.0
CMS1_k127_1991644_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 392.0
CMS1_k127_1991644_4 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 360.0
CMS1_k127_1991644_5 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 303.0
CMS1_k127_1991644_6 PFAM chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001458 276.0
CMS1_k127_1991644_7 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.000000000000000000000000000000000000000000000000000000000000000000305 236.0
CMS1_k127_1991644_8 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000000003134 233.0
CMS1_k127_1991644_9 COG1668 ABC-type Na efflux pump, permease component - - - 0.00000000000000000000000000000000000000000000000000000000000004492 228.0
CMS1_k127_2000245_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.08e-290 904.0
CMS1_k127_2000245_1 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 2.223e-245 767.0
CMS1_k127_2000245_10 RNA-binding protein of the translin family K07477 - - 0.00000000000000000000000000000000000000000000000006973 184.0
CMS1_k127_2000245_11 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000001932 166.0
CMS1_k127_2000245_12 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000004952 170.0
CMS1_k127_2000245_13 Cupredoxin-like domain - - - 0.0000000000000000000000000000000000000000001224 170.0
CMS1_k127_2000245_14 Acetyltransferase (GNAT) domain K03828 - - 0.0000000000000000000000000000000000000009615 153.0
CMS1_k127_2000245_15 - - - - 0.000000000003965 72.0
CMS1_k127_2000245_16 - - - - 0.0000000003495 62.0
CMS1_k127_2000245_2 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 1.423e-204 640.0
CMS1_k127_2000245_3 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 503.0
CMS1_k127_2000245_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 497.0
CMS1_k127_2000245_5 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 440.0
CMS1_k127_2000245_6 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 435.0
CMS1_k127_2000245_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000005169 263.0
CMS1_k127_2000245_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000003687 198.0
CMS1_k127_2000245_9 Uncharacterized protein conserved in archaea (DUF2119) - - - 0.0000000000000000000000000000000000000000000000000000006841 198.0
CMS1_k127_2070678_0 PFAM PilT protein domain protein K06865 - - 3.597e-218 692.0
CMS1_k127_2070678_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01585 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 584.0
CMS1_k127_2070678_10 Protein of unknown function (DUF2769) - - - 0.000000000000000002332 87.0
CMS1_k127_2070678_2 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 511.0
CMS1_k127_2070678_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 461.0
CMS1_k127_2070678_4 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 454.0
CMS1_k127_2070678_5 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 401.0
CMS1_k127_2070678_6 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 305.0
CMS1_k127_2070678_7 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001683 263.0
CMS1_k127_2070678_8 pfam ammecr1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000005204 221.0
CMS1_k127_2070678_9 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000003743 158.0
CMS1_k127_2076604_0 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 1.251e-208 658.0
CMS1_k127_2076604_1 PFAM peptidase M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 366.0
CMS1_k127_2076604_2 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 350.0
CMS1_k127_2076604_3 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 328.0
CMS1_k127_2076604_4 - - - - 0.00000000000000000000000001042 119.0
CMS1_k127_2076604_5 ATP-grasp superfamily K06863 - 6.3.4.23 0.000000000000000000007729 103.0
CMS1_k127_2092173_0 Uncharacterized protein conserved in archaea (DUF2114) - - - 2.027e-200 638.0
CMS1_k127_2092173_1 aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005906 494.0
CMS1_k127_2092173_10 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000001408 216.0
CMS1_k127_2092173_11 - - - - 0.00000000000000000000000000000000000000000003993 172.0
CMS1_k127_2092173_12 Cupredoxin-like domain - - - 0.0000000000000000000000000000000000000000249 157.0
CMS1_k127_2092173_13 Domain of unknown function (DUF1890) - - - 0.0000000000000000000000000000000008277 136.0
CMS1_k127_2092173_14 - - - - 0.000000000000000000000000000000001319 137.0
CMS1_k127_2092173_15 Belongs to the eukaryotic ribosomal protein eS17 family K02962 - - 0.000000000000001825 77.0
CMS1_k127_2092173_16 Domain of unknown function (DUF1894) - - - 0.00000000004365 66.0
CMS1_k127_2092173_17 NifU-like domain - - - 0.00000000006513 66.0
CMS1_k127_2092173_2 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 440.0
CMS1_k127_2092173_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 435.0
CMS1_k127_2092173_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 384.0
CMS1_k127_2092173_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 352.0
CMS1_k127_2092173_6 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009341 344.0
CMS1_k127_2092173_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 331.0
CMS1_k127_2092173_8 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001759 281.0
CMS1_k127_2092173_9 serine-type aminopeptidase activity K14475 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005649 247.0
CMS1_k127_2107379_0 Psort location Cytoplasmic, score - - - 9.057e-200 634.0
CMS1_k127_2108339_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1247.0
CMS1_k127_2108339_1 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.0 1069.0
CMS1_k127_2108339_10 - - - - 0.000000000000000000000000000000000000000000000000002815 191.0
CMS1_k127_2108339_11 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.000000000000000000000000000000000000000000000003934 177.0
CMS1_k127_2108339_12 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear K00195 - - 0.00000000000000000000000000000000000000002637 159.0
CMS1_k127_2108339_13 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000008759 133.0
CMS1_k127_2108339_14 heat shock protein binding - - - 0.000001322 53.0
CMS1_k127_2108339_15 PFAM MscS Mechanosensitive ion channel - - - 0.0006882 51.0
CMS1_k127_2108339_2 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 1.459e-222 698.0
CMS1_k127_2108339_3 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 2.52e-218 685.0
CMS1_k127_2108339_4 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 1.049e-214 672.0
CMS1_k127_2108339_5 COG0531 Amino acid transporters - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 571.0
CMS1_k127_2108339_6 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 381.0
CMS1_k127_2108339_7 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 298.0
CMS1_k127_2108339_8 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001938 256.0
CMS1_k127_2108339_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000005743 237.0
CMS1_k127_2120609_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 5.823e-261 814.0
CMS1_k127_2120609_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 307.0
CMS1_k127_2120609_2 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000001178 180.0
CMS1_k127_2161882_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 580.0
CMS1_k127_2161882_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K22161 - 1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 412.0
CMS1_k127_2161882_2 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K22162 - 1.5.7.2,1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002475 277.0
CMS1_k127_2161882_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000007475 265.0
CMS1_k127_2161882_4 PFAM Appr-1-p processing - - - 0.0000000000000000000000000000000000000000000000000000000001799 208.0
CMS1_k127_2161882_5 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000006216 209.0
CMS1_k127_2161882_6 4Fe-4S dicluster domain K22164 - 1.5.98.3 0.000000000000000000000000000001074 125.0
CMS1_k127_2161882_7 PFAM Deoxyribonuclease rho motif-related TRAM - - - 0.0000000000000000000000004199 105.0
CMS1_k127_2196104_0 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 5.554e-199 629.0
CMS1_k127_2196104_1 Protein-export membrane protein SecD K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 498.0
CMS1_k127_2196104_10 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000001165 110.0
CMS1_k127_2196104_11 S-layer protein - - - 0.000000000000000002533 93.0
CMS1_k127_2196104_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 458.0
CMS1_k127_2196104_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 413.0
CMS1_k127_2196104_4 Lycopene cyclase protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 412.0
CMS1_k127_2196104_5 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 391.0
CMS1_k127_2196104_6 Involved in protein export K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 289.0
CMS1_k127_2196104_7 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001713 284.0
CMS1_k127_2196104_8 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000006289 222.0
CMS1_k127_2196104_9 - - - - 0.0000000000000000000000000000003357 123.0
CMS1_k127_227954_0 Sodium:solute symporter family K03307 - - 1.798e-290 903.0
CMS1_k127_227954_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 9.013e-218 685.0
CMS1_k127_227954_10 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 350.0
CMS1_k127_227954_11 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 323.0
CMS1_k127_227954_12 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 289.0
CMS1_k127_227954_13 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003849 282.0
CMS1_k127_227954_14 COG0224 F0F1-type ATP synthase gamma subunit K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002528 279.0
CMS1_k127_227954_15 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000003575 188.0
CMS1_k127_227954_16 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000002994 161.0
CMS1_k127_227954_17 ATP synthase, Delta/Epsilon chain, beta-sandwich domain K02114 - - 0.0000000000000000000000000000000000000005319 152.0
CMS1_k127_227954_18 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000002077 142.0
CMS1_k127_227954_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000296 134.0
CMS1_k127_227954_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.886e-217 681.0
CMS1_k127_227954_20 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0000000000000000000000000000001114 128.0
CMS1_k127_227954_21 CBS domain - - - 0.0000000000000000000002871 101.0
CMS1_k127_227954_22 Cytochrome c class I - - - 0.000000000000008424 83.0
CMS1_k127_227954_23 N-ATPase, AtpR subunit - - - 0.00000000000001123 78.0
CMS1_k127_227954_24 Cytochrome c K02305 - - 0.0000000000001379 79.0
CMS1_k127_227954_25 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.00000000001582 67.0
CMS1_k127_227954_3 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 559.0
CMS1_k127_227954_4 TGS domain protein K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 535.0
CMS1_k127_227954_5 Sodium:neurotransmitter symporter family K03308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 504.0
CMS1_k127_227954_6 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 432.0
CMS1_k127_227954_7 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 429.0
CMS1_k127_227954_8 Serine dehydrogenase proteinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 395.0
CMS1_k127_227954_9 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 372.0
CMS1_k127_234918_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.0000000000000000000000000000000000000008981 149.0
CMS1_k127_234918_1 TIGRFAM daunorubicin resistance ABC transporter K01990 - - 0.0000000000000000001077 93.0
CMS1_k127_234918_2 ABC-2 family transporter protein K01992 - - 0.00000000000000005563 95.0
CMS1_k127_2353068_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 591.0
CMS1_k127_2353068_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 342.0
CMS1_k127_2353068_2 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004407 267.0
CMS1_k127_2353068_3 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000000001009 224.0
CMS1_k127_2353068_4 Permease - - - 0.00000000000000000000000000000000000000000009391 173.0
CMS1_k127_2353068_5 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000001568 152.0
CMS1_k127_2353068_6 Gar1/Naf1 RNA binding region K07569 - - 0.0000000000000009663 79.0
CMS1_k127_238265_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 608.0
CMS1_k127_238265_1 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 573.0
CMS1_k127_238265_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.000000000000000000000000000002299 121.0
CMS1_k127_238265_11 - - - - 0.000000000000000000000000003392 114.0
CMS1_k127_238265_12 Putative Fe-S cluster - - - 0.0000000000000000009377 89.0
CMS1_k127_238265_13 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.0000000000000261 74.0
CMS1_k127_238265_2 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 548.0
CMS1_k127_238265_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 456.0
CMS1_k127_238265_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 445.0
CMS1_k127_238265_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 311.0
CMS1_k127_238265_6 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000001056 223.0
CMS1_k127_238265_7 - - - - 0.000000000000000000000000000000000000000000000000007836 184.0
CMS1_k127_238265_8 to GB L77117 SP Q58031 PID 1591324 percent identity - - - 0.0000000000000000000000000000000000000000000002518 170.0
CMS1_k127_238265_9 - - - - 0.0000000000000000000000000000000000000000007048 170.0
CMS1_k127_2394285_0 Reduction of methyl-coenzyme M (2-(methylthio) ethanesulfonic acid) with 7-mercaptoheptanoylthreonine phosphate to methane and a heterodisulfide K00399 - 2.8.4.1 4.265e-269 837.0
CMS1_k127_2394285_1 4Fe-4S single cluster domain K01843 - 5.4.3.2 2.085e-230 727.0
CMS1_k127_2394285_10 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 299.0
CMS1_k127_2394285_11 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 296.0
CMS1_k127_2394285_12 FeoA K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000106 243.0
CMS1_k127_2394285_13 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000003073 226.0
CMS1_k127_2394285_14 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000000000000000000001381 218.0
CMS1_k127_2394285_15 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain K07585 - - 0.0000000000000000000000000000000000000000000000000000000000086 213.0
CMS1_k127_2394285_16 eRF1 domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000007885 213.0
CMS1_k127_2394285_17 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000000000000723 186.0
CMS1_k127_2394285_18 PFAM ribosomal protein S8E K02995 - - 0.000000000000000000000000000000000000000000001899 167.0
CMS1_k127_2394285_19 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000172 166.0
CMS1_k127_2394285_2 Ferrous iron transport B domain protein K04759 - - 7.465e-198 635.0
CMS1_k127_2394285_20 Methyl-coenzyme M reductase operon protein D K03422 - - 0.0000000000000000000000000000000000000000002507 163.0
CMS1_k127_2394285_21 2Fe-2S iron-sulfur cluster binding domain K18210 - 1.3.4.1 0.00000000000000000000000000000000000000002316 160.0
CMS1_k127_2394285_22 Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000000000000006983 142.0
CMS1_k127_2394285_23 Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.000000000000000000000000000000007845 131.0
CMS1_k127_2394285_24 Belongs to the PDCD5 family K06875 - - 0.000000000000000000000000003725 113.0
CMS1_k127_2394285_25 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.000000000000000000000001578 105.0
CMS1_k127_2394285_26 CRS1_YhbY K07574 - - 0.00000000000000002059 84.0
CMS1_k127_2394285_27 structural constituent of ribosome K02924 - - 0.0000000000000006816 78.0
CMS1_k127_2394285_3 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 600.0
CMS1_k127_2394285_4 PFAM peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 609.0
CMS1_k127_2394285_5 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 521.0
CMS1_k127_2394285_6 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 508.0
CMS1_k127_2394285_7 small GTP-binding protein K06945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 437.0
CMS1_k127_2394285_8 PFAM Methyl-coenzyme M reductase gamma subunit K00402 - 2.8.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 406.0
CMS1_k127_2394285_9 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 368.0
CMS1_k127_250748_0 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 406.0
CMS1_k127_250748_1 MscS Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 316.0
CMS1_k127_250748_2 - - - - 0.000000000000000000000000000000007095 132.0
CMS1_k127_2626247_0 PFAM Glycosyl transferase family 2 K07027 - - 3.662e-194 621.0
CMS1_k127_2626247_1 Uncharacterized membrane protein (DUF2298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 402.0
CMS1_k127_2626247_2 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.0000000000000000000000000000000000000000000001921 171.0
CMS1_k127_2626247_3 PFAM conserved K07027 - - 0.0000000000000000004607 91.0
CMS1_k127_262667_0 hydroxylamine reductase activity K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 578.0
CMS1_k127_2738988_0 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 587.0
CMS1_k127_2738988_1 TIGRFAM UbiD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 520.0
CMS1_k127_2738988_2 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 513.0
CMS1_k127_2738988_3 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 418.0
CMS1_k127_2738988_4 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 366.0
CMS1_k127_2738988_5 - K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000007921 259.0
CMS1_k127_2738988_6 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrE may be responsible for anchoring the complex to the membrane K08265 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0031224,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0044425,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000005465 203.0
CMS1_k127_2738988_7 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000000000000009703 172.0
CMS1_k127_2738988_8 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.0000000000000009529 77.0
CMS1_k127_2743707_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1270.0
CMS1_k127_2743707_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 8.327e-196 618.0
CMS1_k127_2743707_2 PFAM Semialdehyde dehydrogenase NAD - binding K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 531.0
CMS1_k127_2743707_3 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 361.0
CMS1_k127_2743707_5 4Fe-4S binding domain - - - 0.0000000000000000000008686 96.0
CMS1_k127_2743707_6 - - - - 0.00000000008134 69.0
CMS1_k127_2743707_7 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000007653 50.0
CMS1_k127_2743707_8 Archaeal transcriptional regulator TrmB - - - 0.0003385 50.0
CMS1_k127_2756904_0 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 387.0
CMS1_k127_2756904_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 310.0
CMS1_k127_2756904_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002824 275.0
CMS1_k127_2756904_3 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000000000000000000787 232.0
CMS1_k127_2756904_4 Efflux ABC transporter, permease protein K02004 - - 0.0000000000000000000000000000000000000000000000007435 188.0
CMS1_k127_2756904_5 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000002894 130.0
CMS1_k127_2756904_6 cog cog4393 - - - 0.000000000000000000006185 97.0
CMS1_k127_2759543_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007266 271.0
CMS1_k127_2759543_1 protein conserved in archaea - - - 0.000000000000000008536 91.0
CMS1_k127_2759543_2 mRNA, complete cds - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0008150,GO:0009892,GO:0010468,GO:0010605,GO:0010629,GO:0019222,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0060255,GO:0065007 - 0.0000000261 64.0
CMS1_k127_277166_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 591.0
CMS1_k127_277166_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 392.0
CMS1_k127_277166_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 340.0
CMS1_k127_277166_3 PFAM ATP-NAD AcoX kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 303.0
CMS1_k127_277166_4 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.0000000000000000000000000000000000000003398 153.0
CMS1_k127_277166_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000001004 63.0
CMS1_k127_2776220_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 518.0
CMS1_k127_2776220_1 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 399.0
CMS1_k127_2776220_10 - - - - 0.00000000000001832 82.0
CMS1_k127_2776220_11 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000001905 74.0
CMS1_k127_2776220_12 protein conserved in archaea K09723 - - 0.000002998 58.0
CMS1_k127_2776220_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 379.0
CMS1_k127_2776220_3 Translation initiation factor 2 alpha subunit K03237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 342.0
CMS1_k127_2776220_4 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 322.0
CMS1_k127_2776220_5 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 300.0
CMS1_k127_2776220_6 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 289.0
CMS1_k127_2776220_7 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000001552 180.0
CMS1_k127_2776220_8 binds to the 23S rRNA K02929 - - 0.0000000000000000000000000000000000006785 141.0
CMS1_k127_2776220_9 PFAM Ribosomal protein S27E K02978 - - 0.00000000000000000000003333 99.0
CMS1_k127_2794096_0 in RNase L inhibitor, RLI K06174 - - 2.494e-254 797.0
CMS1_k127_2794096_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 8.239e-226 709.0
CMS1_k127_2794096_10 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 330.0
CMS1_k127_2794096_11 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 309.0
CMS1_k127_2794096_12 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 309.0
CMS1_k127_2794096_13 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 285.0
CMS1_k127_2794096_14 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000011 284.0
CMS1_k127_2794096_15 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005744 268.0
CMS1_k127_2794096_16 Putative RNA methyltransferase K09142 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001865 268.0
CMS1_k127_2794096_17 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000009874 226.0
CMS1_k127_2794096_18 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000338 224.0
CMS1_k127_2794096_19 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000003283 219.0
CMS1_k127_2794096_2 AAA-like domain K06915 - - 6.752e-202 641.0
CMS1_k127_2794096_20 binds to the 23S rRNA K02885 - - 0.00000000000000000000000000000000000000000000000000000000002196 209.0
CMS1_k127_2794096_21 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000000000000000004501 207.0
CMS1_k127_2794096_22 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000009909 205.0
CMS1_k127_2794096_23 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000000000000002857 207.0
CMS1_k127_2794096_24 TIGRFAM ribosomal protein L30P K02907 - - 0.000000000000000000000000000000000000000000000000000000008059 202.0
CMS1_k127_2794096_25 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000000000006316 195.0
CMS1_k127_2794096_26 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000001021 183.0
CMS1_k127_2794096_27 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000011 168.0
CMS1_k127_2794096_28 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000168 164.0
CMS1_k127_2794096_29 - - - - 0.00000000000000000000000000000000000000007261 165.0
CMS1_k127_2794096_3 phosphoenolpyruvate carboxykinase (ATP) activity K01610 - 4.1.1.49 1.578e-198 633.0
CMS1_k127_2794096_30 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.000000000000000000000000000000000007645 139.0
CMS1_k127_2794096_31 Belongs to the eukaryotic ribosomal protein eL32 family K02912 - - 0.000000000000000000000000000000000009512 144.0
CMS1_k127_2794096_32 PFAM regulatory protein, ArsR K21903 - - 0.0000000000000000000000000005756 117.0
CMS1_k127_2794096_33 RNase L inhibitor, RLI - - - 0.000000000000000000000000001718 117.0
CMS1_k127_2794096_34 Domain of unknown function (DUF1805) - - - 0.000000000000000000000000001839 115.0
CMS1_k127_2794096_35 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000000001001 101.0
CMS1_k127_2794096_36 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.0000000000000000000000133 102.0
CMS1_k127_2794096_37 CBS domain - - - 0.00000000000000000000002504 104.0
CMS1_k127_2794096_38 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.000000000000000002783 86.0
CMS1_k127_2794096_39 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000004189 87.0
CMS1_k127_2794096_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 501.0
CMS1_k127_2794096_40 heat shock protein binding - - - 0.0000000004215 68.0
CMS1_k127_2794096_41 - - - - 0.00002662 48.0
CMS1_k127_2794096_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 447.0
CMS1_k127_2794096_6 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 449.0
CMS1_k127_2794096_7 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 415.0
CMS1_k127_2794096_8 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 381.0
CMS1_k127_2794096_9 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 322.0
CMS1_k127_2796030_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009529 311.0
CMS1_k127_2796030_1 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000000000000002274 156.0
CMS1_k127_2796030_2 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000002232 137.0
CMS1_k127_2796030_3 - - - - 0.0001799 49.0
CMS1_k127_2796541_0 Radical SAM domain protein K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001567 262.0
CMS1_k127_2796541_1 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.0000000000000000000000000000000000000000000000000000001188 207.0
CMS1_k127_2796541_2 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000000004317 158.0
CMS1_k127_2796541_3 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000005926 128.0
CMS1_k127_2796541_4 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000001609 71.0
CMS1_k127_2812605_0 AMP-binding enzyme - - - 2.589e-226 709.0
CMS1_k127_2812605_1 PFAM chaperonin Cpn60 TCP-1 K22447 - - 5.899e-200 636.0
CMS1_k127_2812605_10 COG0463 Glycosyltransferases involved in cell wall biogenesis K13002 - - 0.00000000000000000000000000000000000000000000001133 180.0
CMS1_k127_2812605_11 Small Multidrug Resistance protein K03297,K11741 - - 0.000000000000000000000000000000000000135 143.0
CMS1_k127_2812605_12 phosphate transporter K16331 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000001468 102.0
CMS1_k127_2812605_13 PFAM Peptidase S24 S26A S26B, conserved region K13280 - 3.4.21.89 0.0000000000000000000002919 105.0
CMS1_k127_2812605_14 - - - - 0.00000000000000000004335 96.0
CMS1_k127_2812605_15 Sulfurtransferase TusA - - - 0.00000000000000077 80.0
CMS1_k127_2812605_16 - - - - 0.000000000000000832 80.0
CMS1_k127_2812605_17 Winged helix-turn-helix - - - 0.0000000000001964 74.0
CMS1_k127_2812605_18 - - - - 0.000000000003127 77.0
CMS1_k127_2812605_19 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000274 73.0
CMS1_k127_2812605_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 524.0
CMS1_k127_2812605_20 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.000001162 61.0
CMS1_k127_2812605_21 methyltransferase activity - - - 0.00003657 46.0
CMS1_k127_2812605_3 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 498.0
CMS1_k127_2812605_4 sulfate adenylyltransferase K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009189 477.0
CMS1_k127_2812605_5 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 367.0
CMS1_k127_2812605_6 PFAM TatD-related deoxyribonuclease K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 363.0
CMS1_k127_2812605_7 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 314.0
CMS1_k127_2812605_8 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 288.0
CMS1_k127_2812605_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000005693 196.0
CMS1_k127_2821835_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.47e-318 989.0
CMS1_k127_2821835_1 PFAM chaperonin Cpn60 TCP-1 K22447 - - 1.288e-249 780.0
CMS1_k127_2821835_10 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 351.0
CMS1_k127_2821835_11 Methanogenesis marker protein 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 343.0
CMS1_k127_2821835_12 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 341.0
CMS1_k127_2821835_13 Type II secretion system (T2SS), protein F K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 309.0
CMS1_k127_2821835_14 Prenyltransferase and squalene oxidase repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 310.0
CMS1_k127_2821835_15 Type II secretion system (T2SS), protein F K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006884 289.0
CMS1_k127_2821835_16 TrkA-C domain K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000524 284.0
CMS1_k127_2821835_17 TIGRFAM type I restriction system adenine methylase (hsdM) K03427 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002808 273.0
CMS1_k127_2821835_18 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000006723 237.0
CMS1_k127_2821835_19 GrpB protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001255 235.0
CMS1_k127_2821835_2 PFAM type II secretion system protein E K07332 - - 9.13e-222 712.0
CMS1_k127_2821835_20 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000002676 225.0
CMS1_k127_2821835_21 DNA polymerase beta K07076 - - 0.000000000000000000000000000000000000000000000000000000000000926 214.0
CMS1_k127_2821835_22 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000003381 231.0
CMS1_k127_2821835_23 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000005067 216.0
CMS1_k127_2821835_24 COG0433 Predicted ATPase - - - 0.00000000000000000000000000000000000000000000000000000004795 210.0
CMS1_k127_2821835_25 COG1226 Kef-type K transport systems - - - 0.0000000000000000000000000000000000000000000000000000007572 201.0
CMS1_k127_2821835_26 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000003056 178.0
CMS1_k127_2821835_27 NAD(P)H dehydrogenase (quinone) activity - - - 0.0000000000000000000000000000000000000001428 159.0
CMS1_k127_2821835_28 PFAM peptidase - - - 0.0000000000000000000000000000000000005784 148.0
CMS1_k127_2821835_29 zinc metalloprotease whose natural substrate is K06974 - - 0.000000000000000000000000000000000001208 148.0
CMS1_k127_2821835_3 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 1.802e-219 692.0
CMS1_k127_2821835_30 dephospho-CoA kinase activity - - - 0.000000000000000000000000000000000001347 143.0
CMS1_k127_2821835_31 HEPN domain - - - 0.00000000000000000000000000000004617 130.0
CMS1_k127_2821835_32 archaeal Zn-finger protein - - - 0.00000000000000000000000000001733 126.0
CMS1_k127_2821835_33 Protein of unknown function (DUF2769) - - - 0.000000000000000000000000005198 111.0
CMS1_k127_2821835_34 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000007485 116.0
CMS1_k127_2821835_35 protein conserved in archaea - - - 0.0000000000000000008073 98.0
CMS1_k127_2821835_36 - - - - 0.0000000000000002013 83.0
CMS1_k127_2821835_37 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000002331 74.0
CMS1_k127_2821835_38 Involved in cell shape control K22222 - - 0.0000000001702 73.0
CMS1_k127_2821835_39 - - - - 0.000000005269 61.0
CMS1_k127_2821835_4 Erythromycin esterase - - - 4.274e-202 637.0
CMS1_k127_2821835_40 - - - - 0.00000002423 58.0
CMS1_k127_2821835_41 Tubulin like - - - 0.0000001712 65.0
CMS1_k127_2821835_42 - - - - 0.0000001807 55.0
CMS1_k127_2821835_43 Involved in cell shape control K22222 - - 0.000003985 59.0
CMS1_k127_2821835_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 5.289e-198 626.0
CMS1_k127_2821835_6 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 580.0
CMS1_k127_2821835_7 Archaeal Nre, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 467.0
CMS1_k127_2821835_8 Dihydrouridine synthase (Dus) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 426.0
CMS1_k127_2821835_9 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 357.0
CMS1_k127_2822049_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 2.59e-225 711.0
CMS1_k127_2822049_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 550.0
CMS1_k127_2822049_10 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000001946 196.0
CMS1_k127_2822049_11 Fe-S cluster K04488 - - 0.000000000000000000000000000000000000000000000000000101 203.0
CMS1_k127_2822049_12 Thioredoxin domain - - - 0.0000000000000000000000000000000000000000000001748 175.0
CMS1_k127_2822049_13 hydrolase K04794 - 3.1.1.29 0.0000000000000000000000000000000000000000006132 161.0
CMS1_k127_2822049_14 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000008526 167.0
CMS1_k127_2822049_15 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000000000000000000000000000446 154.0
CMS1_k127_2822049_16 Domain of unknown function DUF11 - - - 0.000000000000000000000000000000000000003293 164.0
CMS1_k127_2822049_17 Belongs to the glycosyl hydrolase 26 family K01179 GO:0003674,GO:0003824,GO:0004553,GO:0008810,GO:0016787,GO:0016798 3.2.1.4 0.00000000000000000000000000000005106 138.0
CMS1_k127_2822049_18 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.00000000000000000000001184 102.0
CMS1_k127_2822049_19 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000007799 95.0
CMS1_k127_2822049_2 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 512.0
CMS1_k127_2822049_20 - - - - 0.0000000000000001021 87.0
CMS1_k127_2822049_22 - - - - 0.00000003605 63.0
CMS1_k127_2822049_23 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000057 53.0
CMS1_k127_2822049_24 TIGRFAM redox-active disulfide protein 2 - - - 0.0000008978 54.0
CMS1_k127_2822049_25 - - - - 0.000001297 57.0
CMS1_k127_2822049_3 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 475.0
CMS1_k127_2822049_4 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 441.0
CMS1_k127_2822049_5 PFAM Sugar isomerase (SIS) K08094 - 5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 428.0
CMS1_k127_2822049_6 DNA polymerase beta domain protein region K09717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 381.0
CMS1_k127_2822049_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 329.0
CMS1_k127_2822049_8 Flavoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002808 273.0
CMS1_k127_2822049_9 Glycosyl transferase family 21 K00752 - 2.4.1.212 0.000000000000000000000000000000000000000000000000000000000000000000000000006125 266.0
CMS1_k127_2839618_0 HMGL-like K01649 - 2.3.3.13 5.198e-212 664.0
CMS1_k127_2839618_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 6.97e-210 666.0
CMS1_k127_2839618_10 Metallo-beta-lactamase superfamily K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 366.0
CMS1_k127_2839618_11 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 301.0
CMS1_k127_2839618_12 tRNA 3'-trailer cleavage - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 297.0
CMS1_k127_2839618_13 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004542 269.0
CMS1_k127_2839618_14 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000002735 240.0
CMS1_k127_2839618_15 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.000000000000000000000000000000000000000000000000000000000000000269 224.0
CMS1_k127_2839618_16 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000001723 219.0
CMS1_k127_2839618_17 RmuC family K09760 - - 0.00000000000000000000000000001457 129.0
CMS1_k127_2839618_18 4Fe-4S dicluster domain - - - 0.000000000000000000000000002482 114.0
CMS1_k127_2839618_19 PFAM Thioredoxin K03671 - - 0.00000000000000000000000002072 111.0
CMS1_k127_2839618_2 PFAM Radical SAM domain protein K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 609.0
CMS1_k127_2839618_20 - - - - 0.0000000000000000002525 97.0
CMS1_k127_2839618_21 PQ loop repeat K15383 - - 0.00000000000006544 74.0
CMS1_k127_2839618_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 576.0
CMS1_k127_2839618_4 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 553.0
CMS1_k127_2839618_5 DEAD DEAH box helicase domain protein K05592,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 541.0
CMS1_k127_2839618_6 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 510.0
CMS1_k127_2839618_7 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 505.0
CMS1_k127_2839618_8 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 453.0
CMS1_k127_2839618_9 His Kinase A (phosphoacceptor) domain K07652 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 400.0
CMS1_k127_2855514_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000005621 193.0
CMS1_k127_2855514_1 mRNA binding K07339 - - 0.00000000000000002285 82.0
CMS1_k127_2855514_2 O-Methyltransferase - - - 0.00000002172 59.0
CMS1_k127_2855950_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 383.0
CMS1_k127_2855950_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 292.0
CMS1_k127_2855950_2 COG1361 S-layer domain - - - 0.00000000000000000000000000000000008243 144.0
CMS1_k127_2855950_3 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000002845 102.0
CMS1_k127_2855950_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000222 77.0
CMS1_k127_2875409_0 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 421.0
CMS1_k127_2875409_1 TIGRFAM small GTP-binding protein K06943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 394.0
CMS1_k127_2875409_10 membrane - - - 0.0000000000000000000000000000000000001856 147.0
CMS1_k127_2875409_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000184 116.0
CMS1_k127_2875409_2 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 309.0
CMS1_k127_2875409_3 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 295.0
CMS1_k127_2875409_4 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001864 287.0
CMS1_k127_2875409_5 Flavoprotein K18853 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0042558,GO:0042559,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901283,GO:1901285,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:2001115,GO:2001116,GO:2001117,GO:2001118 1.5.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005085 276.0
CMS1_k127_2875409_6 cytochrome complex assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000001367 236.0
CMS1_k127_2875409_7 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000214 223.0
CMS1_k127_2875409_8 PFAM Sodium calcium exchanger membrane region K07301 GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005262,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006814,GO:0006816,GO:0006873,GO:0006874,GO:0006875,GO:0008150,GO:0008273,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015081,GO:0015085,GO:0015267,GO:0015291,GO:0015297,GO:0015298,GO:0015318,GO:0015368,GO:0015491,GO:0015672,GO:0016020,GO:0016021,GO:0019725,GO:0022803,GO:0022804,GO:0022821,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030955,GO:0031224,GO:0031226,GO:0031402,GO:0031420,GO:0034220,GO:0035725,GO:0042592,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070588,GO:0070838,GO:0071804,GO:0071805,GO:0071944,GO:0072503,GO:0072507,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099516 - 0.000000000000000000000000000000000000000003996 166.0
CMS1_k127_2875409_9 HAD-superfamily hydrolase, subfamily IA, variant 1 K07025 - - 0.00000000000000000000000000000000000003082 153.0
CMS1_k127_2878578_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 7.653e-196 617.0
CMS1_k127_2878578_1 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000001055 182.0
CMS1_k127_2907885_0 Domain of unknown function (DUF814) - - - 2.483e-200 643.0
CMS1_k127_2907885_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 3.946e-198 634.0
CMS1_k127_2907885_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002452 249.0
CMS1_k127_2907885_11 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000406 240.0
CMS1_k127_2907885_12 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000002402 175.0
CMS1_k127_2907885_13 protein deglycation K03152,K05520,K12132 - 2.7.11.1,3.5.1.124 0.00000000000000000000000000000000000000000003416 166.0
CMS1_k127_2907885_14 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.000000000000000000000006174 104.0
CMS1_k127_2907885_15 Belongs to the GbsR family K22109 - - 0.00000000000000000000005821 104.0
CMS1_k127_2907885_16 Family of unknown function (DUF5371) - - - 0.000000001938 59.0
CMS1_k127_2907885_2 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 431.0
CMS1_k127_2907885_3 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 377.0
CMS1_k127_2907885_4 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 364.0
CMS1_k127_2907885_5 DEAD DEAH box helicase domain protein K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 350.0
CMS1_k127_2907885_6 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 306.0
CMS1_k127_2907885_7 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005827 304.0
CMS1_k127_2907885_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 287.0
CMS1_k127_2907885_9 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000002122 244.0
CMS1_k127_2915326_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 4.322e-310 962.0
CMS1_k127_2915326_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 476.0
CMS1_k127_2915326_10 phospholipase C K01114 - 3.1.4.3 0.000000000000000002088 94.0
CMS1_k127_2915326_2 ABC1 family K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 420.0
CMS1_k127_2915326_3 KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 315.0
CMS1_k127_2915326_4 PFAM triphosphoribosyl-dephospho-CoA protein K05966 - 2.4.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 294.0
CMS1_k127_2915326_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000003966 196.0
CMS1_k127_2915326_6 cheY-homologous receiver domain K07668 - - 0.000000000000000000000000000000000000000000000007748 174.0
CMS1_k127_2915326_8 Protein of unknown function (DUF447) K09154 - - 0.00000000000000000000000000000000001276 143.0
CMS1_k127_2915326_9 Roadblock LC7 family protein K07131 - - 0.00000000000000000000000000000000004244 137.0
CMS1_k127_2966252_0 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 5.101e-204 649.0
CMS1_k127_2966252_1 - - - - 0.000000000000000001399 92.0
CMS1_k127_2966252_4 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.0000008019 51.0
CMS1_k127_2996663_0 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 368.0
CMS1_k127_2996663_1 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000008666 179.0
CMS1_k127_2996663_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000001158 151.0
CMS1_k127_305313_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 598.0
CMS1_k127_305313_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007232 483.0
CMS1_k127_305313_2 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 356.0
CMS1_k127_305313_3 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001116 280.0
CMS1_k127_305313_4 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008962 247.0
CMS1_k127_3053708_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 447.0
CMS1_k127_3053708_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 316.0
CMS1_k127_3053708_2 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 295.0
CMS1_k127_3053708_3 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000004173 214.0
CMS1_k127_3053708_4 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000000000000000000000000000000000000000000001024 191.0
CMS1_k127_3053708_5 bacterial-type flagellum-dependent cell motility - - - 0.000000007501 67.0
CMS1_k127_3070351_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 464.0
CMS1_k127_3070351_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 293.0
CMS1_k127_3070351_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000009424 232.0
CMS1_k127_3070351_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000003117 233.0
CMS1_k127_3070351_4 - - - - 0.00000000000000000000000000000000000000000000003562 183.0
CMS1_k127_3077255_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 491.0
CMS1_k127_3077255_1 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 462.0
CMS1_k127_3077255_2 Radical SAM superfamily K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 319.0
CMS1_k127_3077255_3 Belongs to the Protein of K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001722 250.0
CMS1_k127_3077255_4 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000003323 160.0
CMS1_k127_3141761_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.554e-244 764.0
CMS1_k127_3141761_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 518.0
CMS1_k127_3141761_10 Trm112p-like protein - - - 0.000000000000000000000517 96.0
CMS1_k127_3141761_11 RDD family - - - 0.0000000000000000009233 89.0
CMS1_k127_3141761_12 Belongs to the UPF0248 family K09715 - - 0.000000000002391 71.0
CMS1_k127_3141761_2 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 405.0
CMS1_k127_3141761_3 signal transduction protein with CBS domains K07744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 398.0
CMS1_k127_3141761_4 Belongs to the UPF0285 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 347.0
CMS1_k127_3141761_5 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 315.0
CMS1_k127_3141761_6 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000179 221.0
CMS1_k127_3141761_7 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000003043 192.0
CMS1_k127_3141761_8 - - - - 0.00000000000000000000000000000000001165 143.0
CMS1_k127_3141761_9 Flavodoxin - - - 0.0000000000000000000000001756 110.0
CMS1_k127_316712_0 Belongs to the RtcB family K14415 - 6.5.1.3 4.254e-226 709.0
CMS1_k127_316712_1 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 301.0
CMS1_k127_316712_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000001611 198.0
CMS1_k127_316712_3 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000000000000000000000001059 155.0
CMS1_k127_3167795_0 Urocanase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 569.0
CMS1_k127_3167795_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 506.0
CMS1_k127_3167795_2 TIGRFAM 2-oxoacid acceptor oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 490.0
CMS1_k127_3167795_3 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 426.0
CMS1_k127_3167795_4 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 402.0
CMS1_k127_3167795_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 313.0
CMS1_k127_3167795_6 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.000000000000000000000000000000000000000004003 161.0
CMS1_k127_3167795_7 Putative TM nitroreductase - - - 0.00000000000000000000000000181 118.0
CMS1_k127_3210764_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1531.0
CMS1_k127_3210764_1 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 313.0
CMS1_k127_321605_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 579.0
CMS1_k127_321605_1 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 340.0
CMS1_k127_3232450_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 1.165e-226 724.0
CMS1_k127_3232450_1 Uncharacterised protein family (UPF0182) K09118 - - 2.47e-197 646.0
CMS1_k127_3232450_10 - - - - 0.0000000000000001314 82.0
CMS1_k127_3232450_11 - - - - 0.000000000000000461 84.0
CMS1_k127_3232450_2 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP-binding K00158 - 1.2.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 497.0
CMS1_k127_3232450_3 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 476.0
CMS1_k127_3232450_4 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 409.0
CMS1_k127_3232450_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 385.0
CMS1_k127_3232450_6 amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000005957 198.0
CMS1_k127_3232450_7 PFAM PUA domain containing protein K07398 - - 0.000000000000000000000000000000000000000000000001339 178.0
CMS1_k127_3232450_8 helix_turn_helix ASNC type K03718,K03719 - - 0.00000000000000000000000000000000000000000007626 164.0
CMS1_k127_3232450_9 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.000000000000000000000002371 106.0
CMS1_k127_3251619_0 DEAD DEAH box helicase domain protein K03724 - - 5.279e-258 812.0
CMS1_k127_3296470_0 Domain of unknown function (DUF296) K06934 - - 0.0000000000000000000000000000000000000000000005418 169.0
CMS1_k127_3296470_1 Peptidase S8 S53, subtilisin kexin sedolisin - - - 0.000000000000000000000000003596 126.0
CMS1_k127_3296470_2 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000001051 61.0
CMS1_k127_331634_0 domain, Protein K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 466.0
CMS1_k127_331634_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 328.0
CMS1_k127_331634_2 Dihydrouridine synthase (Dus) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 326.0
CMS1_k127_331634_3 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009795 268.0
CMS1_k127_331634_4 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000003525 237.0
CMS1_k127_331634_5 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000002929 167.0
CMS1_k127_331634_6 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000000000003062 70.0
CMS1_k127_3599981_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 563.0
CMS1_k127_3599981_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 356.0
CMS1_k127_3599981_2 Bax inhibitor 1 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 298.0
CMS1_k127_3599981_3 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003254 236.0
CMS1_k127_3599981_4 Protein of unknown function TPD sequence-motif - - - 0.00000000000000000000000000000000000000000000000000000000001349 215.0
CMS1_k127_3599981_5 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000001062 208.0
CMS1_k127_3599981_6 Peptidase S8 S53, subtilisin kexin sedolisin - - - 0.000000000000000000000000000000000000000008619 164.0
CMS1_k127_3599981_7 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000007367 154.0
CMS1_k127_3599981_8 Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.000000000000002187 78.0
CMS1_k127_3599981_9 Universal stress protein family - - - 0.000000000002581 72.0
CMS1_k127_3602759_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 424.0
CMS1_k127_3602759_1 PFAM Conserved TM helix repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001461 268.0
CMS1_k127_3602759_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000001408 248.0
CMS1_k127_3602759_3 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.00000000000000000000000000000000000000000000000000000000000000000002544 240.0
CMS1_k127_3602759_4 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000001235 193.0
CMS1_k127_3602759_5 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000000001972 138.0
CMS1_k127_3602759_6 Membrane protein, UPF0016 and UPF0016 domain-containing - - - 0.00000000000000000000000000000006505 131.0
CMS1_k127_3602759_7 PAS domain - - - 0.00007754 53.0
CMS1_k127_3603899_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 438.0
CMS1_k127_3603899_1 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000000000000000003754 175.0
CMS1_k127_3603899_2 - - - - 0.0000000000000000000000000001441 124.0
CMS1_k127_3636005_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000002898 204.0
CMS1_k127_3636005_1 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000002259 160.0
CMS1_k127_3636005_2 PFAM MazG nucleotide pyrophosphohydrolase - - - 0.000000000000000003949 85.0
CMS1_k127_3643634_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009882 522.0
CMS1_k127_3643634_1 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 454.0
CMS1_k127_3643634_2 Phosphoribosyl transferase domain K07101 - - 0.00000000000000000000000000000000000000000000000000000000001047 214.0
CMS1_k127_3643634_3 PKD domain - - - 0.000000000000000000000000000000000000000000000000000003357 216.0
CMS1_k127_3643634_4 Endonuclease K07451 - - 0.000000009089 63.0
CMS1_k127_3649950_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 612.0
CMS1_k127_3649950_1 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 470.0
CMS1_k127_3649950_10 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0003578 52.0
CMS1_k127_3649950_2 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 378.0
CMS1_k127_3649950_3 Methanogenesis marker protein 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 342.0
CMS1_k127_3649950_4 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000006212 263.0
CMS1_k127_3649950_5 Co Zn Cd efflux system component K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000166 244.0
CMS1_k127_3649950_6 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000008362 199.0
CMS1_k127_3649950_7 Cytochrome b subunit of formate K14069 - 1.12.98.3 0.0000000000000000000000000000000000000000000001173 177.0
CMS1_k127_3649950_8 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000000000000002152 145.0
CMS1_k127_3649950_9 Zinc-dependent metalloprotease - - - 0.000001297 57.0
CMS1_k127_365272_0 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000001224 242.0
CMS1_k127_365272_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000991 168.0
CMS1_k127_365272_2 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000001989 159.0
CMS1_k127_365272_3 Conserved repeat domain - - - 0.000000000001284 80.0
CMS1_k127_365272_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000234 66.0
CMS1_k127_366497_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 467.0
CMS1_k127_366497_1 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 462.0
CMS1_k127_366497_10 - - - - 0.00000000000001398 84.0
CMS1_k127_366497_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 400.0
CMS1_k127_366497_3 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 394.0
CMS1_k127_366497_4 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 389.0
CMS1_k127_366497_5 SMART Elongator protein 3 MiaB NifB K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 357.0
CMS1_k127_366497_6 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 294.0
CMS1_k127_366497_7 Protein of unknown function (DUF1699) - - - 0.00000000000000000000000000000000000000000000000003956 181.0
CMS1_k127_366497_8 PFAM dihydropteroate synthase, DHPS - - - 0.000000000000000000000000000001853 124.0
CMS1_k127_366497_9 protein conserved in archaea - - - 0.0000000000000000000000007042 107.0
CMS1_k127_3672402_0 Belongs to the MCM family K10726 - - 8.783e-267 840.0
CMS1_k127_3672402_1 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 597.0
CMS1_k127_3672402_10 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003948 261.0
CMS1_k127_3672402_11 ATP-grasp domain K06913 - - 0.000000000000000000000000000000000000000000000000000000000000000001231 242.0
CMS1_k127_3672402_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000002729 213.0
CMS1_k127_3672402_13 KH domain protein K06961 - - 0.000000000000000000000000000000000000000000000000000000004243 203.0
CMS1_k127_3672402_14 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.00000000000000000000000000000000000000000000000000001033 196.0
CMS1_k127_3672402_15 Circadian clock protein KaiC K06945 - - 0.0000000000000000000000000000000000000000000000000007209 191.0
CMS1_k127_3672402_16 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.00000000000000000000000000000000000000000000000000396 186.0
CMS1_k127_3672402_17 archaeal coiled-coil protein - - - 0.000000000000000000000000000000000000000000000001005 187.0
CMS1_k127_3672402_18 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000009556 183.0
CMS1_k127_3672402_19 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.000000000000000000000000000000000000000001131 170.0
CMS1_k127_3672402_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 595.0
CMS1_k127_3672402_20 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.00000000000000000000000000000000000000001473 158.0
CMS1_k127_3672402_21 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000000000004069 154.0
CMS1_k127_3672402_22 Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000000000000002364 144.0
CMS1_k127_3672402_23 Protein of unknown function (DUF2551) - - - 0.0000000000000000000000000000000003239 134.0
CMS1_k127_3672402_24 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000004142 96.0
CMS1_k127_3672402_25 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A K02944 - - 0.0000000000000003815 79.0
CMS1_k127_3672402_26 - - - - 0.00000000009055 70.0
CMS1_k127_3672402_27 metallopeptidase activity K02323,K03110,K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,2.7.7.7 0.0000000001209 74.0
CMS1_k127_3672402_28 Mo-molybdopterin cofactor metabolic process - - - 0.000000002535 59.0
CMS1_k127_3672402_29 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000001038 62.0
CMS1_k127_3672402_3 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 471.0
CMS1_k127_3672402_4 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 431.0
CMS1_k127_3672402_5 small GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 427.0
CMS1_k127_3672402_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 420.0
CMS1_k127_3672402_7 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 348.0
CMS1_k127_3672402_8 Circadian clock protein KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 316.0
CMS1_k127_3672402_9 serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002729 284.0
CMS1_k127_3700493_0 TIGRFAM TraB family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 437.0
CMS1_k127_3700493_1 tRNAHis guanylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002771 248.0
CMS1_k127_3700493_2 - - - - 0.00000000000000000000000000000000007303 153.0
CMS1_k127_3700493_3 PFAM PRC-barrel domain - - - 0.000000000000000000000275 98.0
CMS1_k127_3700493_4 PFAM PKD domain containing protein - - - 0.0000000000143 78.0
CMS1_k127_3700493_5 CARDB - - - 0.000000001057 70.0
CMS1_k127_3700493_6 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000333 59.0
CMS1_k127_3702167_0 PEP-utilising enzyme, TIM barrel domain K01006 - 2.7.9.1 0.0 1198.0
CMS1_k127_3702167_1 Peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 461.0
CMS1_k127_3702167_10 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000004829 113.0
CMS1_k127_3702167_11 - - - - 0.0001407 48.0
CMS1_k127_3702167_2 Uncharacterised protein family (UPF0014) K02069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 302.0
CMS1_k127_3702167_3 ATPases associated with a variety of cellular activities K02068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002654 269.0
CMS1_k127_3702167_4 Family of unknown function (DUF5402) - - - 0.000000000000000000000000000000000000000000563 160.0
CMS1_k127_3702167_5 PAC2 family K06869 - - 0.00000000000000000000000000000000000000001115 162.0
CMS1_k127_3702167_6 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000001081 138.0
CMS1_k127_3702167_8 response to heat - - - 0.0000000000000000000000000000003823 126.0
CMS1_k127_3702167_9 - - - - 0.0000000000000000000000000002622 123.0
CMS1_k127_3703800_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 6.476e-195 616.0
CMS1_k127_3703800_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 517.0
CMS1_k127_3703800_2 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 458.0
CMS1_k127_3703800_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 318.0
CMS1_k127_3703800_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 285.0
CMS1_k127_3703800_5 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000002019 226.0
CMS1_k127_3703800_6 PFAM UDP-N-acetylglucosamine 2-epimerase K01791 GO:0003674,GO:0003824,GO:0008761,GO:0016853,GO:0016854,GO:0016857 5.1.3.14 0.00000000000000000000000000000000000000009625 153.0
CMS1_k127_3703800_7 Rubrerythrin - - - 0.00000000000000000000000000000003845 127.0
CMS1_k127_3703807_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 9.423e-300 929.0
CMS1_k127_3703807_1 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 524.0
CMS1_k127_3703807_10 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 296.0
CMS1_k127_3703807_11 Bacterial regulatory protein, arsR family K07725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 285.0
CMS1_k127_3703807_12 RimK domain protein ATP-grasp K05844,K15740 - 6.3.2.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002453 287.0
CMS1_k127_3703807_13 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009133 269.0
CMS1_k127_3703807_14 cytidyltransferase-related domain K00952 - 2.7.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000006634 249.0
CMS1_k127_3703807_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008451 248.0
CMS1_k127_3703807_16 Rhomboid family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000004443 240.0
CMS1_k127_3703807_17 protein folding in endoplasmic reticulum K19134 - - 0.000000000000000000000000000000000000000000000000000000000000000005162 233.0
CMS1_k127_3703807_18 S4 RNA-binding domain K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000004519 224.0
CMS1_k127_3703807_19 Uncharacterized protein conserved in archaea (DUF2150) - - - 0.0000000000000000000000000000000000000000000000000000000001012 211.0
CMS1_k127_3703807_2 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 456.0
CMS1_k127_3703807_20 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000004761 210.0
CMS1_k127_3703807_21 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.0000000000000000000000000000000000000000000000000227 188.0
CMS1_k127_3703807_22 Protein of unknown function (DUF434) - - - 0.0000000000000000000000000000000000000000000667 168.0
CMS1_k127_3703807_23 binds to the 23S rRNA K02921 - - 0.0000000000000000000000000000002033 127.0
CMS1_k127_3703807_24 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.0000000000000000000000000000005655 129.0
CMS1_k127_3703807_25 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000000000000000009574 124.0
CMS1_k127_3703807_26 RNA binding K07581 - - 0.000000000000000000000000243 111.0
CMS1_k127_3703807_27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.0000000000000002534 78.0
CMS1_k127_3703807_28 protein conserved in archaea K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.000003286 52.0
CMS1_k127_3703807_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 391.0
CMS1_k127_3703807_4 DHH family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 392.0
CMS1_k127_3703807_5 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 365.0
CMS1_k127_3703807_6 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 361.0
CMS1_k127_3703807_7 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005091 353.0
CMS1_k127_3703807_8 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K22162 - 1.5.7.2,1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 332.0
CMS1_k127_3703807_9 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 316.0
CMS1_k127_3723112_0 Subtilase family K01342 - 3.4.21.62 0.00000000000000000000000008128 124.0
CMS1_k127_3723112_1 extracellular matrix structural constituent - - - 0.00000000000000000000000036 110.0
CMS1_k127_3723112_2 Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. - - - 0.00000000000000000009179 105.0
CMS1_k127_3723112_3 PKD domain containing protein - - - 0.00000319 57.0
CMS1_k127_3726877_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1617.0
CMS1_k127_3726877_1 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 470.0
CMS1_k127_3726877_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000000000002197 193.0
CMS1_k127_3726877_3 NAD(P)H dehydrogenase (quinone) activity - - - 0.0000000000000000000000000000000006881 137.0
CMS1_k127_3726877_4 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III K00784 - 3.1.26.11 0.0000000000000000000004741 98.0
CMS1_k127_3726877_5 PFAM glutaredoxin K06191 - - 0.00000000000007507 72.0
CMS1_k127_3769210_0 Protein of unknown function (DUF460) K09150 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 583.0
CMS1_k127_3769210_1 Pfam:DUF258 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
CMS1_k127_3769210_2 PFAM Thiamine pyrophosphate enzyme, C-terminal K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000007321 262.0
CMS1_k127_3769210_3 V4R K07013 - - 0.00000000000000000000000000000000000000000000000000000000000000003652 231.0
CMS1_k127_3769210_4 chlorophyll binding - - - 0.000000000000000000000000000000000000003623 159.0
CMS1_k127_3769210_5 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000000007774 99.0
CMS1_k127_3769210_6 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000009856 98.0
CMS1_k127_3793526_0 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 559.0
CMS1_k127_3793526_1 Has ATPase and non-specific DNA-binding activities K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 524.0
CMS1_k127_3793526_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 423.0
CMS1_k127_3793526_3 PFAM metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 336.0
CMS1_k127_3793526_4 PFAM conserved K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000151 280.0
CMS1_k127_3793526_5 - - - - 0.000000000000000000000000000000000000000001194 160.0
CMS1_k127_3793526_6 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000001333 132.0
CMS1_k127_3793526_7 Thiamine-binding protein - - - 0.0000000000000005129 81.0
CMS1_k127_3793526_8 Tetratricopeptide repeat - - - 0.0000000000000006244 89.0
CMS1_k127_3851255_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 360.0
CMS1_k127_3851255_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036,K02068,K06857 - 3.6.3.27,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 345.0
CMS1_k127_3851255_2 phosphate transport system permease protein K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 323.0
CMS1_k127_3851284_0 PFAM ABC transporter K00400 - - 2.522e-236 741.0
CMS1_k127_3851284_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 6.181e-196 620.0
CMS1_k127_3851284_10 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.00000000000000000000000000000000000000000000000000000000000001553 218.0
CMS1_k127_3851284_11 Pyruvate kinase, alpha/beta domain K09126 - - 0.0000000000000000000000000000000000000000000000000000000000003517 216.0
CMS1_k127_3851284_12 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000519 187.0
CMS1_k127_3851284_13 membrane - - - 0.00000000000000000000000000000000000000000000000001042 188.0
CMS1_k127_3851284_14 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.00000000000000000000000000000000000017 145.0
CMS1_k127_3851284_15 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.00000000000000000000000000000001371 134.0
CMS1_k127_3851284_16 - - - - 0.0000000000000000000000000000008587 123.0
CMS1_k127_3851284_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 592.0
CMS1_k127_3851284_3 Belongs to the UPF0288 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 488.0
CMS1_k127_3851284_4 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 415.0
CMS1_k127_3851284_5 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 382.0
CMS1_k127_3851284_6 methanogenesis marker protein 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 374.0
CMS1_k127_3851284_7 PspA/IM30 family K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 318.0
CMS1_k127_3851284_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000198 280.0
CMS1_k127_3851284_9 protein conserved in archaea K09746 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004905 256.0
CMS1_k127_3859082_0 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 438.0
CMS1_k127_3859082_1 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 371.0
CMS1_k127_3859082_10 Uncharacterized protein conserved in archaea (DUF2180) - - - 0.0000000000000000008079 87.0
CMS1_k127_3859082_11 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis - - - 0.00000002463 66.0
CMS1_k127_3859082_12 S-layer protein - - - 0.0001106 54.0
CMS1_k127_3859082_2 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 371.0
CMS1_k127_3859082_3 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 360.0
CMS1_k127_3859082_4 PFAM glutamate synthase alpha subunit K00202 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 360.0
CMS1_k127_3859082_5 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000173 214.0
CMS1_k127_3859082_6 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000000000000000000000000000000000000000000000001693 182.0
CMS1_k127_3859082_7 CGGC - - - 0.000000000000000000000000000000000000000000000001001 176.0
CMS1_k127_3859082_8 Uncharacterized protein conserved in archaea (DUF2180) - - - 0.00000000000000000000000000004488 117.0
CMS1_k127_3859082_9 COG1522 Transcriptional regulators - - - 0.000000000000000000000000271 106.0
CMS1_k127_3868863_0 ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 411.0
CMS1_k127_3868863_1 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 315.0
CMS1_k127_3868863_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 306.0
CMS1_k127_3868863_3 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.00000000000000000000000000000000000000000000000000000000000000000003483 237.0
CMS1_k127_3868863_4 RNA binding K09736 - - 0.000000000000000009071 86.0
CMS1_k127_3900976_0 Flavodoxin - - - 0.00000000000000000000000000002692 121.0
CMS1_k127_3900976_1 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000003979 120.0
CMS1_k127_3913500_0 Domain of unknown function (DUF4872) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 411.0
CMS1_k127_3913500_1 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007577 278.0
CMS1_k127_3913500_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000001925 216.0
CMS1_k127_3913500_3 - - - - 0.000000000000000000000000000000000000000000000000000266 197.0
CMS1_k127_3913500_4 4Fe-4S ferredoxin iron-sulfur binding domain - - - 0.0000000000000000003438 98.0
CMS1_k127_3913500_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.163,2.1.1.201 0.000000000000000001448 93.0
CMS1_k127_3914833_0 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000006127 206.0
CMS1_k127_3914833_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000002592 147.0
CMS1_k127_3914833_2 - - - - 0.0000000000000000000000000000000000001159 154.0
CMS1_k127_3914833_3 - - - - 0.0000000000000000000000000000000004009 142.0
CMS1_k127_3914833_4 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000002622 102.0
CMS1_k127_3919711_0 Belongs to the glutamate synthase family - - - 9.92e-218 685.0
CMS1_k127_3919711_1 Cys/Met metabolism PLP-dependent enzyme K19793 - 2.6.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 524.0
CMS1_k127_3919711_10 metallopeptidase activity - - - 0.00000000000000111 90.0
CMS1_k127_3919711_11 Prokaryotic cytochrome b561 K00127 - - 0.0000000006641 68.0
CMS1_k127_3919711_2 Serine dehydrogenase proteinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 291.0
CMS1_k127_3919711_3 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000001068 229.0
CMS1_k127_3919711_4 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000001539 183.0
CMS1_k127_3919711_5 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000064 175.0
CMS1_k127_3919711_6 Nitroreductase family - - - 0.0000000000000000000000000000000000000000003529 165.0
CMS1_k127_3919711_7 PFAM Cytochrome b5 - - - 0.00000000000000000000000000000000000000001367 164.0
CMS1_k127_3919711_8 Protein of unknown function (DUF2769) - - - 0.000000000000000000000001316 106.0
CMS1_k127_3919711_9 to GB L77117 SP Q58031 PID 1591324 percent identity - - - 0.0000000000000000724 85.0
CMS1_k127_3947568_0 PFAM Cation K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 599.0
CMS1_k127_3947568_1 DeoC/LacD family aldolase K08321,K11645 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.245,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 383.0
CMS1_k127_3947568_2 - - - - 0.00000000000000000000000000000000001903 151.0
CMS1_k127_3947568_3 - - - - 0.00000000002853 69.0
CMS1_k127_3947568_4 extracellular matrix structural constituent - - - 0.00008203 51.0
CMS1_k127_3956988_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 367.0
CMS1_k127_3956988_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 341.0
CMS1_k127_3956988_2 6-phosphogluconolactonase activity - - - 0.0000000000000000000000000000000000000000000000000000004394 213.0
CMS1_k127_3956988_3 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000004733 165.0
CMS1_k127_3956988_4 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000002936 126.0
CMS1_k127_3957866_0 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 310.0
CMS1_k127_3957866_1 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008288 291.0
CMS1_k127_3957866_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000214 223.0
CMS1_k127_3957866_3 HAD-superfamily hydrolase, subfamily IA, variant 1 K07025 - - 0.000000000000000000000000000000000000581 149.0
CMS1_k127_3957866_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000009766 117.0
CMS1_k127_3998572_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1464.0
CMS1_k127_3998572_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 3.466e-212 665.0
CMS1_k127_3998572_10 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 353.0
CMS1_k127_3998572_11 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 329.0
CMS1_k127_3998572_12 Belongs to the UPF0284 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 323.0
CMS1_k127_3998572_13 MgtC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 308.0
CMS1_k127_3998572_14 Membrane protein of unknown function DUF63 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 288.0
CMS1_k127_3998572_15 methyltransferase small K07579 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003408 277.0
CMS1_k127_3998572_17 Belongs to the UPF0215 family K09120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001014 258.0
CMS1_k127_3998572_18 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000002517 225.0
CMS1_k127_3998572_19 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000000000000000000000000000000000000000000000001832 205.0
CMS1_k127_3998572_2 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 568.0
CMS1_k127_3998572_20 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000002218 205.0
CMS1_k127_3998572_21 ABC transporter, ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000004742 186.0
CMS1_k127_3998572_22 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000007 161.0
CMS1_k127_3998572_23 Belongs to the UPF0179 family K09730 - - 0.00000000000000000000000000000000000000009141 154.0
CMS1_k127_3998572_24 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000000000000001099 145.0
CMS1_k127_3998572_25 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000001133 136.0
CMS1_k127_3998572_26 - - - - 0.00000000000000000000000001573 113.0
CMS1_k127_3998572_27 Rhodanese Homology Domain - - - 0.00000000000000000000000007001 111.0
CMS1_k127_3998572_28 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.0000000000000000000000006699 106.0
CMS1_k127_3998572_29 CcmE K02197 - - 0.000000000000000000008062 96.0
CMS1_k127_3998572_3 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 545.0
CMS1_k127_3998572_30 Stage II sporulation protein M K06384 - - 0.0000000000000000001033 98.0
CMS1_k127_3998572_31 Family of unknown function (DUF5350) - - - 0.00000000002306 65.0
CMS1_k127_3998572_32 PFAM Pyridoxamine 5'-phosphate K07006 - - 0.0000000002297 66.0
CMS1_k127_3998572_33 - - - - 0.0000000008835 72.0
CMS1_k127_3998572_34 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.000000001674 60.0
CMS1_k127_3998572_35 Transcriptional regulator - - - 0.0007487 49.0
CMS1_k127_3998572_4 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 509.0
CMS1_k127_3998572_5 AAA domain (Cdc48 subfamily) K07392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008181 453.0
CMS1_k127_3998572_6 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 453.0
CMS1_k127_3998572_7 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 436.0
CMS1_k127_3998572_8 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 417.0
CMS1_k127_3998572_9 Subtilase family K01342 - 3.4.21.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 395.0
CMS1_k127_3998703_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1109.0
CMS1_k127_3998703_1 Oligopeptidase F K08602 - - 2.333e-208 664.0
CMS1_k127_3998703_10 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.0000000000000000000000000000000000000000000000000000000001871 210.0
CMS1_k127_3998703_11 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000003158 204.0
CMS1_k127_3998703_12 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000000000000000218 202.0
CMS1_k127_3998703_13 PFAM Nucleoside recognition - - - 0.000000000000000000000000000000000000000000000000001802 194.0
CMS1_k127_3998703_14 transmembrane transporter activity K02008 - - 0.000000000000000000000000000002337 130.0
CMS1_k127_3998703_15 HEPN domain - - - 0.000000000000000000004523 98.0
CMS1_k127_3998703_16 Cupredoxin-like domain - - - 0.000000000000000000007847 97.0
CMS1_k127_3998703_17 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000009037 73.0
CMS1_k127_3998703_18 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000009578 55.0
CMS1_k127_3998703_19 - K02009 - - 0.0000003915 55.0
CMS1_k127_3998703_2 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 518.0
CMS1_k127_3998703_3 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 382.0
CMS1_k127_3998703_4 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 337.0
CMS1_k127_3998703_5 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 303.0
CMS1_k127_3998703_6 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 296.0
CMS1_k127_3998703_7 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001604 288.0
CMS1_k127_3998703_8 DNA ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000001699 237.0
CMS1_k127_3998703_9 Protein of unknown function (DUF432) K09149 - - 0.00000000000000000000000000000000000000000000000000000000000000176 225.0
CMS1_k127_4024940_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 530.0
CMS1_k127_4024940_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 443.0
CMS1_k127_4024940_10 - - - - 0.00000000000000000000001817 106.0
CMS1_k127_4024940_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000000000002507 102.0
CMS1_k127_4024940_12 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000000148 91.0
CMS1_k127_4024940_13 chlorophyll binding - - - 0.00000000000000001284 93.0
CMS1_k127_4024940_14 PFAM glutaredoxin K06191 - - 0.000000000000000815 78.0
CMS1_k127_4024940_15 H subunit K02107 - - 0.000000005418 61.0
CMS1_k127_4024940_16 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.000002563 57.0
CMS1_k127_4024940_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 379.0
CMS1_k127_4024940_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 347.0
CMS1_k127_4024940_4 archaeosine synthase activity K07557 - 2.6.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 289.0
CMS1_k127_4024940_5 Zn-dependent protease with chaperone function K03799,K06013 - 3.4.24.84 0.000000000000000000000000000000000000000006342 164.0
CMS1_k127_4024940_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000000000000000000000008661 160.0
CMS1_k127_4024940_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000008042 154.0
CMS1_k127_4024940_8 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000001262 123.0
CMS1_k127_4024940_9 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000001251 122.0
CMS1_k127_4112394_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 597.0
CMS1_k127_4112394_1 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 509.0
CMS1_k127_4112394_11 Belongs to the thymidylate synthase family. Archaeal- type ThyA subfamily K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000004093 194.0
CMS1_k127_4112394_12 - - - - 0.00000000000000000000000000000000000000000000000000001571 202.0
CMS1_k127_4112394_13 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000000009227 188.0
CMS1_k127_4112394_14 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000004326 169.0
CMS1_k127_4112394_16 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.000000000000000000000000000000000000119 149.0
CMS1_k127_4112394_17 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.00000000000000000000000000000000002452 138.0
CMS1_k127_4112394_18 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.00000000000000000000000000000000003556 139.0
CMS1_k127_4112394_19 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.0000000000000000000000000000000003063 135.0
CMS1_k127_4112394_2 Proton-conducting membrane transporter K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 454.0
CMS1_k127_4112394_20 Na+/H+ ion antiporter subunit K05569 - - 0.0000000000000000000000000000001482 129.0
CMS1_k127_4112394_21 Na+/H+ antiporter subunit K05571 - - 0.0000000000000000000000000009162 115.0
CMS1_k127_4112394_22 metallopeptidase activity - - - 0.000000000000000000000000002174 117.0
CMS1_k127_4112394_23 - K00960 - 2.7.7.6 0.0000000000000000000009754 95.0
CMS1_k127_4112394_24 Domain of unknown function (DUF4040) - - - 0.000000000000000000278 89.0
CMS1_k127_4112394_25 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.000000000000000001237 87.0
CMS1_k127_4112394_26 Rhodanese Homology Domain - - - 0.0000000000000003827 90.0
CMS1_k127_4112394_28 Domain of unknown function (DUF4870) - - - 0.00000000000005846 76.0
CMS1_k127_4112394_30 Domain related to MnhB subunit of Na+/H+ antiporter K05566,K14118 - - 0.000003721 52.0
CMS1_k127_4112394_4 ApbE family K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 328.0
CMS1_k127_4112394_5 RnfC Barrel sandwich hybrid domain K03615 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 301.0
CMS1_k127_4112394_8 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003335 276.0
CMS1_k127_4112394_9 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000006298 267.0
CMS1_k127_4120387_0 DNA polymerase X family K02347,K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 554.0
CMS1_k127_4120387_1 COG2133 Glucose sorbosone dehydrogenases - - - 0.0000000000000001633 85.0
CMS1_k127_4130530_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 564.0
CMS1_k127_4130530_1 PFAM TrkA-C domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 501.0
CMS1_k127_4130530_10 SMART regulatory protein AsnC Lrp family K22225 - - 0.00000000000000000000000000000000000000000000000000000000000000000001885 235.0
CMS1_k127_4130530_11 Transcription elongation factor Spt5 K02601 - - 0.000000000000000000000000000000000000000000000000000000000000004027 220.0
CMS1_k127_4130530_12 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000008595 216.0
CMS1_k127_4130530_13 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000000446 200.0
CMS1_k127_4130530_14 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000000001575 117.0
CMS1_k127_4130530_15 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.00000000000008699 72.0
CMS1_k127_4130530_16 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00001506 47.0
CMS1_k127_4130530_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 482.0
CMS1_k127_4130530_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 462.0
CMS1_k127_4130530_4 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 377.0
CMS1_k127_4130530_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 361.0
CMS1_k127_4130530_6 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 300.0
CMS1_k127_4130530_7 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001569 269.0
CMS1_k127_4130530_8 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000008145 261.0
CMS1_k127_4130530_9 to cation transporters K07244 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001006 261.0
CMS1_k127_4134345_0 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 451.0
CMS1_k127_4134345_1 PFAM Formylmethanofuran tetrahydromethanopterin formyltransferase Ftr K00672 - 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009278 365.0
CMS1_k127_4134345_2 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 296.0
CMS1_k127_4134345_3 - - - - 0.0000000000000000000000000000005506 141.0
CMS1_k127_4134345_4 methyl-accepting chemotaxis protein K03406,K07652 - 2.7.13.3 0.00000000000007882 76.0
CMS1_k127_4134345_5 Calcium-activated chloride channel regulator K05027,K05030 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005215,GO:0005216,GO:0005229,GO:0005253,GO:0005254,GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006821,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008509,GO:0015075,GO:0015103,GO:0015108,GO:0015267,GO:0015276,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0016324,GO:0016787,GO:0019538,GO:0022803,GO:0022834,GO:0022836,GO:0022838,GO:0022839,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045177,GO:0051179,GO:0051234,GO:0055085,GO:0061778,GO:0070011,GO:0071704,GO:0071944,GO:0098590,GO:0098656,GO:0098660,GO:0098661,GO:0140096,GO:1901564,GO:1902476 - 0.00000000002734 76.0
CMS1_k127_4134345_6 toxin activity - - - 0.00000007014 63.0
CMS1_k127_4134345_7 - - - - 0.000002418 57.0
CMS1_k127_4134345_8 - - - - 0.00006328 55.0
CMS1_k127_418655_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 9.22e-269 836.0
CMS1_k127_418655_1 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 3.633e-220 692.0
CMS1_k127_418655_10 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00579 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003883 286.0
CMS1_k127_418655_11 NADH ubiquinone oxidoreductase, 20 Kd subunit K22159 - 1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001035 268.0
CMS1_k127_418655_12 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000404 223.0
CMS1_k127_418655_13 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000008634 168.0
CMS1_k127_418655_14 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00578 - 2.1.1.86 0.00000000000000000000000001813 111.0
CMS1_k127_418655_15 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00583 - 2.1.1.86 0.0000000000000003526 80.0
CMS1_k127_418655_16 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.0000000000006306 71.0
CMS1_k127_418655_17 TIGRFAM tetrahydromethanopterin S-methyltransferase, F subunit K00582 - 2.1.1.86 0.000000000003871 69.0
CMS1_k127_418655_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.048e-200 632.0
CMS1_k127_418655_3 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 583.0
CMS1_k127_418655_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 562.0
CMS1_k127_418655_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 519.0
CMS1_k127_418655_6 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 473.0
CMS1_k127_418655_7 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00581 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 384.0
CMS1_k127_418655_8 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 334.0
CMS1_k127_418655_9 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00580 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 290.0
CMS1_k127_4384012_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 3.349e-298 932.0
CMS1_k127_4384012_1 GDP dissociation inhibitor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 561.0
CMS1_k127_4384012_2 Segregation and condensation complex subunit ScpB K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 393.0
CMS1_k127_4384012_3 Segregation and condensation protein ScpA K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000001274 238.0
CMS1_k127_4384012_4 - - - - 0.0000000000000000000000000000000000000000000000001364 188.0
CMS1_k127_4384012_5 Methyltransferase domain - - - 0.000000000000000000008722 100.0
CMS1_k127_4502098_0 zinc-ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 379.0
CMS1_k127_4502098_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000001977 201.0
CMS1_k127_4502098_2 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000001098 206.0
CMS1_k127_4502098_3 peptidyl-tyrosine sulfation K00525,K01768 - 1.17.4.1,4.6.1.1 0.000000000000000000000000000000000000000000000000000002188 199.0
CMS1_k127_4502098_4 - - - - 0.0000000000000000000000000000000000004122 147.0
CMS1_k127_4502098_5 PIN domain K07065 - - 0.00000000007797 67.0
CMS1_k127_4502098_6 - - - - 0.0000004241 55.0
CMS1_k127_4502098_7 - - - - 0.00004407 50.0
CMS1_k127_4507941_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 3.039e-222 695.0
CMS1_k127_4507941_1 acid binding OB-fold tRNA helicase-type K07463 - - 3.485e-220 696.0
CMS1_k127_4507941_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 443.0
CMS1_k127_4507941_3 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 418.0
CMS1_k127_4507941_4 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000001484 259.0
CMS1_k127_4507941_5 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000459 191.0
CMS1_k127_4513916_0 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 452.0
CMS1_k127_4513916_1 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000004228 190.0
CMS1_k127_4518108_0 PFAM PKD domain containing protein - - - 0.000000000000000000000000007738 127.0
CMS1_k127_452548_0 Protein of unknown function (DUF531) K09725 - - 0.0000000000000000000000000000000000000000000000000000000008473 204.0
CMS1_k127_452548_1 Belongs to the peptidase S16 family K06870 - - 0.00000000000000000000000000000000000000000000000000000000764 216.0
CMS1_k127_4537337_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 394.0
CMS1_k127_4537337_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 309.0
CMS1_k127_4537337_10 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000001648 150.0
CMS1_k127_4537337_11 - - - - 0.0000000000000000000000001796 116.0
CMS1_k127_4537337_12 Thioredoxin domain - - - 0.000000000000000003218 87.0
CMS1_k127_4537337_13 Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation - - - 0.0000000000002325 72.0
CMS1_k127_4537337_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 306.0
CMS1_k127_4537337_3 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000205 282.0
CMS1_k127_4537337_4 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005953 270.0
CMS1_k127_4537337_5 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000001043 266.0
CMS1_k127_4537337_6 COG1138 Cytochrome c biogenesis factor K02198 - - 0.0000000000000000000000000000000000000000000000000003192 209.0
CMS1_k127_4537337_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000001975 179.0
CMS1_k127_4537337_8 Rubrerythrin K19824 - - 0.0000000000000000000000000000000000000202 149.0
CMS1_k127_4537337_9 Putative heavy-metal-binding - - - 0.000000000000000000000000000000000009051 138.0
CMS1_k127_4546864_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 2.089e-202 647.0
CMS1_k127_4546864_1 Chloride channel K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 584.0
CMS1_k127_4546864_10 PFAM CBS domain containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000002927 80.0
CMS1_k127_4546864_11 Putative small multi-drug export protein - - - 0.000001518 58.0
CMS1_k127_4546864_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 503.0
CMS1_k127_4546864_3 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 363.0
CMS1_k127_4546864_4 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 322.0
CMS1_k127_4546864_5 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 288.0
CMS1_k127_4546864_6 Haloacid dehalogenase-like hydrolase K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000008681 242.0
CMS1_k127_4546864_7 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000000001798 226.0
CMS1_k127_4546864_8 Putative Fe-S cluster - - - 0.00000000000000000000000004471 110.0
CMS1_k127_4546864_9 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000239 102.0
CMS1_k127_4591591_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 1.789e-199 626.0
CMS1_k127_4591591_1 Proton-conducting membrane transporter K22168 - 1.5.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 530.0
CMS1_k127_4591591_10 F420H2 dehydrogenase subunit FpoO K22170 - 1.5.98.3 0.00000000000000004885 85.0
CMS1_k127_4591591_11 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K22167 - 1.5.98.3 0.0001411 45.0
CMS1_k127_4591591_2 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 512.0
CMS1_k127_4591591_3 Proton-conducting membrane transporter K22169 - 1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 481.0
CMS1_k127_4591591_4 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008001 367.0
CMS1_k127_4591591_5 SMART Elongator protein 3 MiaB NifB K15865 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009143 371.0
CMS1_k127_4591591_6 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008305 287.0
CMS1_k127_4591591_7 - - - - 0.0000000000000000000000000000000001726 137.0
CMS1_k127_4591591_8 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000007888 128.0
CMS1_k127_4591591_9 PFAM molydopterin dinucleotide-binding region K00203 - 1.2.7.12 0.00000000000000000000000001055 113.0
CMS1_k127_4597268_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.394e-204 648.0
CMS1_k127_4597268_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 5.58e-202 645.0
CMS1_k127_4597268_10 - - - - 0.000000000000000000000000000000000000000000000000000000003444 205.0
CMS1_k127_4597268_11 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000007002 193.0
CMS1_k127_4597268_12 - - - - 0.00000000000000000000000000000000000000000104 170.0
CMS1_k127_4597268_13 Roadblock LC7 family protein K07131 - - 0.00000000000005417 76.0
CMS1_k127_4597268_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 524.0
CMS1_k127_4597268_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 526.0
CMS1_k127_4597268_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 509.0
CMS1_k127_4597268_5 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 486.0
CMS1_k127_4597268_6 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 455.0
CMS1_k127_4597268_7 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008417 445.0
CMS1_k127_4597268_8 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003453 282.0
CMS1_k127_4597268_9 PFAM thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000005567 241.0
CMS1_k127_4613792_0 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 1.15e-284 893.0
CMS1_k127_4613792_1 S-layer protein - - - 5.23e-207 691.0
CMS1_k127_4613792_10 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 312.0
CMS1_k127_4613792_11 protein conserved in archaea K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001413 264.0
CMS1_k127_4613792_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000005831 225.0
CMS1_k127_4613792_14 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000004381 153.0
CMS1_k127_4613792_15 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000001477 149.0
CMS1_k127_4613792_16 peptidase U32 K08303 - - 0.000000000000000000000000000000000006901 148.0
CMS1_k127_4613792_17 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000234 95.0
CMS1_k127_4613792_19 - - - - 0.000000003175 61.0
CMS1_k127_4613792_2 PFAM Radical SAM domain protein K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 565.0
CMS1_k127_4613792_3 phosphoesterase RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 541.0
CMS1_k127_4613792_4 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 525.0
CMS1_k127_4613792_5 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 522.0
CMS1_k127_4613792_6 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 504.0
CMS1_k127_4613792_7 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 393.0
CMS1_k127_4613792_8 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 351.0
CMS1_k127_4613792_9 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 342.0
CMS1_k127_4616396_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 383.0
CMS1_k127_4616396_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 329.0
CMS1_k127_4616396_10 Belongs to the sulfur carrier protein TusA family - - - 0.0001312 47.0
CMS1_k127_4616396_2 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 317.0
CMS1_k127_4616396_3 COG0095 Lipoate-protein ligase A K03800 GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0051604,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901681 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000004411 227.0
CMS1_k127_4616396_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000001344 165.0
CMS1_k127_4616396_5 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.000000000000000000000000000000000000000396 157.0
CMS1_k127_4616396_6 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.00000000000000000000000009205 111.0
CMS1_k127_4616396_7 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.000000000000000007267 89.0
CMS1_k127_4616396_8 - - - - 0.00000000000002464 77.0
CMS1_k127_4616396_9 Lipoate-protein ligase a K03800 - 6.3.1.20 0.000000001124 63.0
CMS1_k127_4722573_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17870 - 1.6.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009034 309.0
CMS1_k127_4722573_1 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 298.0
CMS1_k127_4722573_10 PFAM Radical SAM domain protein K07129 - - 0.0000000000003655 72.0
CMS1_k127_4722573_11 4Fe-4S binding domain - - - 0.000000000003767 68.0
CMS1_k127_4722573_2 CcmB protein K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003375 246.0
CMS1_k127_4722573_3 ATPases associated with a variety of cellular activities K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000004294 247.0
CMS1_k127_4722573_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000007831 229.0
CMS1_k127_4722573_5 Thioredoxin K03671 - - 0.00000000000000000000000000000000006653 137.0
CMS1_k127_4722573_6 PIN domain of ribonuclease K07060 - - 0.0000000000000000000000000000000005955 136.0
CMS1_k127_4722573_7 Protein of unknown function (DUF2551) - - - 0.000000000000000000000000000000007544 129.0
CMS1_k127_4722573_8 Predicted membrane protein (DUF2254) - - - 0.000000000000000000009219 107.0
CMS1_k127_4722573_9 - - - - 0.00000000000001177 86.0
CMS1_k127_4728384_0 protein catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 436.0
CMS1_k127_4728384_1 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 299.0
CMS1_k127_4728384_2 - - - - 0.00000000000000000000000000000000001717 141.0
CMS1_k127_4728384_3 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000658 130.0
CMS1_k127_4728384_4 - - - - 0.0004365 52.0
CMS1_k127_4765709_0 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 593.0
CMS1_k127_4765709_1 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 333.0
CMS1_k127_4765709_2 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000259 206.0
CMS1_k127_4765709_3 parallel beta-helix repeat - - - 0.0000000000000000000000000000001006 142.0
CMS1_k127_4765709_4 COG0737 5'-nucleotidase 2',3'-cyclic phosphodiesterase and related esterases K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.00005352 56.0
CMS1_k127_4847589_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 406.0
CMS1_k127_4847589_1 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 292.0
CMS1_k127_4847589_2 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000000000002792 142.0
CMS1_k127_4847589_3 DNA polymerase beta domain protein region K07075 - - 0.000000000000002219 76.0
CMS1_k127_4949179_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 3.883e-219 689.0
CMS1_k127_4949179_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 524.0
CMS1_k127_4949179_10 sulfur carrier activity K04085 - - 0.000000000000094 74.0
CMS1_k127_4949179_11 - - - - 0.000000000002908 73.0
CMS1_k127_4949179_12 - - - - 0.00000000000951 68.0
CMS1_k127_4949179_13 Putative zinc- or iron-chelating domain K06940 - - 0.00000006083 61.0
CMS1_k127_4949179_14 tRNA wobble position uridine thiolation K07237 - - 0.00000008617 57.0
CMS1_k127_4949179_15 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K07235 - - 0.00000009906 58.0
CMS1_k127_4949179_16 DsrE/DsrF-like family - - - 0.0000003484 56.0
CMS1_k127_4949179_17 DsrE family K06039 - - 0.00002294 51.0
CMS1_k127_4949179_18 PFAM DsrE family protein K06039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840 - 0.0007876 47.0
CMS1_k127_4949179_2 Domain of unknown function (DUF1743) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 387.0
CMS1_k127_4949179_3 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 313.0
CMS1_k127_4949179_4 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002532 265.0
CMS1_k127_4949179_5 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000006379 218.0
CMS1_k127_4949179_6 Von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000002944 151.0
CMS1_k127_4949179_7 transcriptional - - - 0.0000000000000000000000000000001682 125.0
CMS1_k127_4949179_8 Putative zinc ribbon domain - - - 0.0000000000000000001237 91.0
CMS1_k127_4949179_9 Urm1 (Ubiquitin related modifier) K03636 - - 0.0000000000000000009921 88.0
CMS1_k127_4962914_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 2.326e-196 631.0
CMS1_k127_4962914_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 366.0
CMS1_k127_4962914_10 Yip1 domain - - - 0.00009404 53.0
CMS1_k127_4962914_2 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 370.0
CMS1_k127_4962914_3 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 378.0
CMS1_k127_4962914_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 317.0
CMS1_k127_4962914_5 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 299.0
CMS1_k127_4962914_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000003682 254.0
CMS1_k127_4962914_7 FmdE, Molybdenum formylmethanofuran dehydrogenase operon - - - 0.000000000000000000000000000000000000000000000001144 180.0
CMS1_k127_4962914_8 DNA ligase D, 3-phosphoesterase domain - - - 0.00000000000000000000000000000000000002149 147.0
CMS1_k127_4962914_9 PFAM 4Fe-4S ferredoxin - - - 0.00000000000002765 75.0
CMS1_k127_5013567_0 KH, type 1, domain K07041 - - 0.0 1013.0
CMS1_k127_5013567_1 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 1.52e-316 984.0
CMS1_k127_5013567_10 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 501.0
CMS1_k127_5013567_11 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 467.0
CMS1_k127_5013567_12 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 425.0
CMS1_k127_5013567_13 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 409.0
CMS1_k127_5013567_14 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006924 401.0
CMS1_k127_5013567_15 Fic/DOC family N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 402.0
CMS1_k127_5013567_16 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 375.0
CMS1_k127_5013567_17 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 370.0
CMS1_k127_5013567_18 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 362.0
CMS1_k127_5013567_19 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 319.0
CMS1_k127_5013567_2 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 5.605e-251 786.0
CMS1_k127_5013567_20 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 293.0
CMS1_k127_5013567_21 Protein of unknown function (DUF1616) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003536 276.0
CMS1_k127_5013567_22 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001228 278.0
CMS1_k127_5013567_23 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002307 267.0
CMS1_k127_5013567_24 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004308 258.0
CMS1_k127_5013567_25 PFAM HhH-GPD family protein K07457 - - 0.0000000000000000000000000000000000000000000000000000000002206 210.0
CMS1_k127_5013567_26 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000004276 201.0
CMS1_k127_5013567_27 ribosomal protein S15 K02956 - - 0.000000000000000000000000000000000000000000000000000461 187.0
CMS1_k127_5013567_28 COG0438 Glycosyltransferase - - - 0.00000000000000000000000000000000000000000000000001103 193.0
CMS1_k127_5013567_29 PFAM glycosyl transferase group 1 K13677 - 2.4.1.208 0.00000000000000000000000000000000000000001955 166.0
CMS1_k127_5013567_3 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 9.509e-239 746.0
CMS1_k127_5013567_30 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000001156 165.0
CMS1_k127_5013567_31 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000001524 163.0
CMS1_k127_5013567_32 - - - - 0.0000000000000000000000000000000000000004303 169.0
CMS1_k127_5013567_33 PFAM glycosyl transferase group 1 K13677 - 2.4.1.208 0.00000000000000000000000000000000000007155 156.0
CMS1_k127_5013567_34 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.00000000000000000000000000000000001802 138.0
CMS1_k127_5013567_35 glycosyl transferase group 1 - - - 0.0000000000000000000000000000004831 128.0
CMS1_k127_5013567_36 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000008661 135.0
CMS1_k127_5013567_37 Belongs to the UPF0147 family K09721 - - 0.00000000000000000000000000001228 119.0
CMS1_k127_5013567_38 PFAM PRC-barrel domain - - - 0.0000000000000000000000001977 108.0
CMS1_k127_5013567_39 Thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000003413 111.0
CMS1_k127_5013567_4 Type II/IV secretion system protein - - - 5.336e-221 709.0
CMS1_k127_5013567_40 Methyltransferase FkbM domain - - - 0.000000000000000000001839 104.0
CMS1_k127_5013567_41 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) K07143 - - 0.000000000000000002994 91.0
CMS1_k127_5013567_42 4Fe-4S binding domain - - - 0.000000000001182 70.0
CMS1_k127_5013567_43 - - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 - 0.0000000001394 66.0
CMS1_k127_5013567_5 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 597.0
CMS1_k127_5013567_6 YHS domain K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 573.0
CMS1_k127_5013567_7 DEAD DEAH box helicase domain protein K10896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 561.0
CMS1_k127_5013567_8 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 538.0
CMS1_k127_5013567_9 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 518.0
CMS1_k127_5056385_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.66e-225 709.0
CMS1_k127_5056385_1 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 486.0
CMS1_k127_5056385_10 Desulfoferrodoxin ferrous iron-binding K05919 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016721,GO:0019430,GO:0022900,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.2 0.000002041 51.0
CMS1_k127_5056385_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 324.0
CMS1_k127_5056385_3 RNA methylase K07446 - 2.1.1.213 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 306.0
CMS1_k127_5056385_4 Oxidoreductase molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000002428 214.0
CMS1_k127_5056385_5 Catalyzes the dephosphorylation of 2-6 carbon acid sugars in vitro K01101 - 3.1.3.41 0.00000000000000000000000000000000000000000000000000000000268 208.0
CMS1_k127_5056385_6 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000001348 158.0
CMS1_k127_5056385_7 SNARE associated Golgi protein K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.00000000000000000000000000000000000005326 150.0
CMS1_k127_5056385_8 - - - - 0.00000000000000001574 89.0
CMS1_k127_5056385_9 - - - - 0.0000000000000323 84.0
CMS1_k127_5081273_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 427.0
CMS1_k127_5081273_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005623 242.0
CMS1_k127_5081273_3 metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000007982 151.0
CMS1_k127_5081273_4 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000000009778 138.0
CMS1_k127_515_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 535.0
CMS1_k127_515_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 437.0
CMS1_k127_515_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 332.0
CMS1_k127_515_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000005932 221.0
CMS1_k127_515_4 CHRD domain - - - 0.000000000000000000000000000000000003107 156.0
CMS1_k127_5391086_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 445.0
CMS1_k127_5391086_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 399.0
CMS1_k127_5391086_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01259 - 3.4.11.5 0.0000000000000000000000000000000000877 143.0
CMS1_k127_5400871_0 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 554.0
CMS1_k127_5400871_1 Permeases of the major facilitator superfamily K08153 - - 0.000000000000000000002215 101.0
CMS1_k127_5401868_0 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 604.0
CMS1_k127_5401868_1 Belongs to the arginase family K01479 - 3.5.3.8 0.00000000000000000000000000000000000000000000000000002223 199.0
CMS1_k127_5401868_2 Serine protease with a broad substrate specificity K17734 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005509,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000004901 180.0
CMS1_k127_5401868_3 - - - - 0.00000000000000000000000635 119.0
CMS1_k127_5401868_4 Kelch motif - - - 0.00000196 62.0
CMS1_k127_5401868_5 heat shock protein binding - - - 0.00004057 57.0
CMS1_k127_5408761_0 COG3387 Glucoamylase and related glycosyl hydrolases - - - 1.386e-202 638.0
CMS1_k127_5408761_1 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 454.0
CMS1_k127_5408761_2 Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG) K07026 - 3.1.3.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 311.0
CMS1_k127_5408761_3 TIGRFAM arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.00000000000000000000000000000000000000000000004091 181.0
CMS1_k127_5408761_5 PFAM Radical SAM domain protein K07129 - - 0.00000000000000000000000007081 108.0
CMS1_k127_5408761_6 Methyltransferase domain - - - 0.00000000000000000000001885 109.0
CMS1_k127_5408761_7 Bacterio-opsin activator HTH K06930,K06988 - 1.5.1.40 0.0000000000002499 79.0
CMS1_k127_5411763_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 3.489e-254 794.0
CMS1_k127_5411763_1 PFAM peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 479.0
CMS1_k127_5411763_10 - - - - 0.000000000000001452 89.0
CMS1_k127_5411763_2 ATPase associated with various cellular activities, AAA_5 K03924,K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000586 411.0
CMS1_k127_5411763_3 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 381.0
CMS1_k127_5411763_4 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 290.0
CMS1_k127_5411763_5 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006408 255.0
CMS1_k127_5411763_6 Pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000003231 163.0
CMS1_k127_5411763_7 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000001386 165.0
CMS1_k127_5411763_8 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000008504 114.0
CMS1_k127_5411763_9 oxidoreductase subunit delta K00171 - 1.2.7.1 0.0000000000000000001415 91.0
CMS1_k127_5412729_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 6.156e-242 756.0
CMS1_k127_5412729_1 - - - - 1.908e-221 704.0
CMS1_k127_5412729_10 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 389.0
CMS1_k127_5412729_11 Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2) heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K22163 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 388.0
CMS1_k127_5412729_12 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 388.0
CMS1_k127_5412729_13 Rio2, N-terminal K07179 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 382.0
CMS1_k127_5412729_14 PFAM PP-loop domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007859 378.0
CMS1_k127_5412729_15 Sulfide dehydrogenase (Flavoprotein) subunit SudB K00528,K02823 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 377.0
CMS1_k127_5412729_16 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 304.0
CMS1_k127_5412729_17 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 301.0
CMS1_k127_5412729_18 NADH ubiquinone oxidoreductase, 20 Kd subunit K22159 - 1.5.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 290.0
CMS1_k127_5412729_19 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004696 280.0
CMS1_k127_5412729_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 6.724e-199 628.0
CMS1_k127_5412729_20 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001609 274.0
CMS1_k127_5412729_21 Necessary for normal cell division and for the maintenance of normal septation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001578 258.0
CMS1_k127_5412729_22 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002911 257.0
CMS1_k127_5412729_23 PFAM CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001285 230.0
CMS1_k127_5412729_24 PFAM ATP-grasp domain K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000009382 226.0
CMS1_k127_5412729_25 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K22160 - 1.5.98.3 0.0000000000000000000000000000000000000000000008253 172.0
CMS1_k127_5412729_26 Domain of unknown function (DUF366) K09139 - - 0.00000000000000000000000000000000000000007332 158.0
CMS1_k127_5412729_27 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K22158 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016695,GO:0046995,GO:0051911,GO:0055114 1.5.98.3 0.0000000000000000000000000000000000000007011 151.0
CMS1_k127_5412729_28 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000001903 153.0
CMS1_k127_5412729_29 4Fe-4S dicluster domain K22164 - 1.5.98.3 0.0000000000000000000000000000000000003544 143.0
CMS1_k127_5412729_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K22167 - 1.5.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 565.0
CMS1_k127_5412729_30 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000000000003342 133.0
CMS1_k127_5412729_31 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K22166 - 1.5.98.3 0.000000000000000000000000000001501 124.0
CMS1_k127_5412729_32 ThiS family K03636 - - 0.000000000000000002126 88.0
CMS1_k127_5412729_33 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K22165 - 1.5.98.3 0.0000000000001079 76.0
CMS1_k127_5412729_34 - - - - 0.000000000001975 67.0
CMS1_k127_5412729_35 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K22165 - 1.5.98.3 0.000002417 53.0
CMS1_k127_5412729_4 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 474.0
CMS1_k127_5412729_5 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K22161 - 1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 455.0
CMS1_k127_5412729_6 RNA ligase K07468 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 416.0
CMS1_k127_5412729_7 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 404.0
CMS1_k127_5412729_8 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 404.0
CMS1_k127_5412729_9 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 385.0
CMS1_k127_5501163_0 Oxidoreductase K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 413.0
CMS1_k127_5501163_1 peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 342.0
CMS1_k127_5501163_2 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000003467 231.0
CMS1_k127_5501163_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000002699 214.0
CMS1_k127_5501163_4 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000007072 174.0
CMS1_k127_5501163_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000005569 134.0
CMS1_k127_5501163_6 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.000000000000000000000000002139 127.0
CMS1_k127_5501163_7 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.00000000000000000000000001206 111.0
CMS1_k127_5504443_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 459.0
CMS1_k127_5504443_1 sequence-specific DNA binding - - - 0.00000000000000000000000000007115 117.0
CMS1_k127_5504443_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000002801 113.0
CMS1_k127_5527139_0 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 5.931e-214 682.0
CMS1_k127_5527139_1 Belongs to the glutamate synthase family - - - 1.533e-204 645.0
CMS1_k127_5527139_10 Belongs to the UPF0218 family K09735 - - 0.000000000000000000000000000000000000000000004552 169.0
CMS1_k127_5527139_11 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.0000000000000000000000000000000000009586 142.0
CMS1_k127_5527139_12 Large family of predicted nucleotide-binding domains K07158 - - 0.000000000000000000000000000003059 123.0
CMS1_k127_5527139_13 COG3030 Protein affecting phage T7 exclusion by the F plasmid K07113 - - 0.000000000000000000000000000003796 123.0
CMS1_k127_5527139_14 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000000271 91.0
CMS1_k127_5527139_15 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000000000005667 91.0
CMS1_k127_5527139_16 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000000002378 85.0
CMS1_k127_5527139_17 - - - - 0.0000000000002409 81.0
CMS1_k127_5527139_18 HEPN domain - - - 0.000000000005243 72.0
CMS1_k127_5527139_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 594.0
CMS1_k127_5527139_3 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 429.0
CMS1_k127_5527139_4 PFAM ABC transporter related K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 379.0
CMS1_k127_5527139_5 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 347.0
CMS1_k127_5527139_6 PFAM ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 344.0
CMS1_k127_5527139_7 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 328.0
CMS1_k127_5527139_8 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000008096 258.0
CMS1_k127_5527139_9 PFAM glutamate synthase alpha subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001532 251.0
CMS1_k127_5551594_0 PFAM Aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 546.0
CMS1_k127_5551594_1 TIGRFAM small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 511.0
CMS1_k127_5551594_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000002206 241.0
CMS1_k127_5551594_3 PFAM regulatory protein AsnC Lrp family - - - 0.000000000000000000000000000000000000000000000000000000000287 206.0
CMS1_k127_5551594_4 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000003247 169.0
CMS1_k127_5551594_5 Mechanosensitive ion channel K16052 - - 0.00000002577 61.0
CMS1_k127_5562286_0 Heat shock 70 kDa protein K04043 - - 8.799e-254 796.0
CMS1_k127_5562286_1 DEAD DEAH box helicase domain protein K03725 - - 6.944e-246 784.0
CMS1_k127_5562286_10 - - - - 0.00000000000000000000000000000000000000000001731 178.0
CMS1_k127_5562286_11 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000001197 143.0
CMS1_k127_5562286_12 meiotic spindle midzone assembly K18626,K20478 GO:0000003,GO:0000070,GO:0000212,GO:0000226,GO:0000278,GO:0000280,GO:0000775,GO:0000776,GO:0000777,GO:0000779,GO:0000793,GO:0000819,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005819,GO:0005856,GO:0006996,GO:0007010,GO:0007017,GO:0007049,GO:0007051,GO:0007059,GO:0008104,GO:0008150,GO:0008608,GO:0009987,GO:0015630,GO:0016043,GO:0022402,GO:0022414,GO:0022607,GO:0031134,GO:0032991,GO:0033036,GO:0034508,GO:0034622,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044427,GO:0044430,GO:0044446,GO:0044464,GO:0045132,GO:0048285,GO:0051179,GO:0051225,GO:0051255,GO:0051257,GO:0051276,GO:0051304,GO:0051306,GO:0051307,GO:0051316,GO:0051321,GO:0051382,GO:0051383,GO:0065003,GO:0065004,GO:0070925,GO:0071824,GO:0071840,GO:0098687,GO:0098813,GO:0140013,GO:0140014,GO:1903046,GO:1903047 - 0.00002335 59.0
CMS1_k127_5562286_2 PFAM Chaperonin Cpn60 TCP-1 K22447 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 568.0
CMS1_k127_5562286_3 Involved in cell shape control K22222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 511.0
CMS1_k127_5562286_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 447.0
CMS1_k127_5562286_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 358.0
CMS1_k127_5562286_6 SMART regulatory protein, Crp K07730 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 346.0
CMS1_k127_5562286_7 actin actin family protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006507 289.0
CMS1_k127_5562286_8 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002535 244.0
CMS1_k127_5562286_9 ArsR transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000008171 211.0
CMS1_k127_5569685_0 Radical SAM K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 541.0
CMS1_k127_5569685_1 SMART regulatory protein AsnC Lrp family K22225 - - 0.000000000000000000000000000000000000000000000000003203 185.0
CMS1_k127_5569685_2 TRAM domain - - - 0.00000000000000000003827 91.0
CMS1_k127_5569685_3 - K00960 - 2.7.7.6 0.000000000000000004263 84.0
CMS1_k127_5605242_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 3.357e-197 631.0
CMS1_k127_5605242_1 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 459.0
CMS1_k127_5605242_10 - - - - 0.00000000000000000271 94.0
CMS1_k127_5605242_11 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.000000000000000006256 87.0
CMS1_k127_5605242_12 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000009817 57.0
CMS1_k127_5605242_13 Protein of unknown function (DUF2953) - - - 0.000008866 56.0
CMS1_k127_5605242_2 shikimate kinase activity K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 325.0
CMS1_k127_5605242_3 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002246 272.0
CMS1_k127_5605242_4 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000005189 229.0
CMS1_k127_5605242_5 Protein of unknown function (DUF1699) - - - 0.0000000000000000000000000000000000000000000000000003205 187.0
CMS1_k127_5605242_6 Protein of unknown function (DUF1699) - - - 0.00000000000000000000000000000000000000000000006793 171.0
CMS1_k127_5605242_7 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000191 141.0
CMS1_k127_5605242_8 chorismate mutase K04093 - 5.4.99.5 0.0000000000000000000000007377 106.0
CMS1_k127_5605242_9 Pfam:DUF2276 - - - 0.00000000000000000000569 92.0
CMS1_k127_5672830_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 4.173e-276 858.0
CMS1_k127_5672830_1 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 330.0
CMS1_k127_5672830_2 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001047 270.0
CMS1_k127_5672830_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000003795 245.0
CMS1_k127_5672830_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535 - 3.6.3.6 0.00000001373 58.0
CMS1_k127_5732392_0 Major facilitator superfamily K19576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001985 287.0
CMS1_k127_5732392_1 Iron permease FTR1 family K07243 - - 0.000000000000000000000000000000000000000000000000000000000003537 218.0
CMS1_k127_5732392_2 - - - - 0.0000000000000000000000000000000000000000000000000001789 188.0
CMS1_k127_5893855_0 PFAM ferredoxin-dependent glutamate synthase - - - 7.77e-283 877.0
CMS1_k127_5893855_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 8.518e-203 638.0
CMS1_k127_5893855_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 2.633e-202 636.0
CMS1_k127_5893855_3 Ammonium Transporter K03320 - - 1.716e-194 612.0
CMS1_k127_5893855_4 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000008705 213.0
CMS1_k127_5893855_5 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000002561 180.0
CMS1_k127_5893855_6 PFAM glutamine amidotransferase, class-II - - - 0.000000000000000000000001256 111.0
CMS1_k127_69450_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1159.0
CMS1_k127_69450_1 - - - - 1.207e-220 702.0
CMS1_k127_69450_10 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000006114 157.0
CMS1_k127_69450_11 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.000000000000000000000000000000000001081 143.0
CMS1_k127_69450_12 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000001465 117.0
CMS1_k127_69450_13 PFAM Yip1 domain - - - 0.000000000000000000000001716 110.0
CMS1_k127_69450_14 COG1522 Transcriptional regulators - - - 0.000000000000000000000001963 110.0
CMS1_k127_69450_15 - - - - 0.0000000000000000000001597 102.0
CMS1_k127_69450_16 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000003296 92.0
CMS1_k127_69450_17 - - - - 0.000000000000000001988 93.0
CMS1_k127_69450_18 - - - - 0.000000000000000002294 98.0
CMS1_k127_69450_19 - - - - 0.000000000000000002454 89.0
CMS1_k127_69450_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 579.0
CMS1_k127_69450_20 Transcriptional regulator - - - 0.0000000000000006559 81.0
CMS1_k127_69450_21 - - - - 0.0000000000005784 74.0
CMS1_k127_69450_22 Protein of unknown function with PCYCGC motif - - - 0.00000000002537 76.0
CMS1_k127_69450_23 Protein of unknown function, DUF255 - - - 0.000000002111 65.0
CMS1_k127_69450_24 - - - - 0.00000002049 61.0
CMS1_k127_69450_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 524.0
CMS1_k127_69450_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 448.0
CMS1_k127_69450_5 COG1138 Cytochrome c biogenesis factor K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 333.0
CMS1_k127_69450_6 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001985 250.0
CMS1_k127_69450_7 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000001423 243.0
CMS1_k127_69450_8 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000002283 194.0
CMS1_k127_69450_9 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000009806 177.0
CMS1_k127_903343_0 SMART Elongator protein 3 MiaB NifB K22226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 603.0
CMS1_k127_903343_1 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 395.0
CMS1_k127_903343_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 370.0
CMS1_k127_903343_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000001884 232.0
CMS1_k127_903343_4 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000004593 235.0
CMS1_k127_903343_5 - - - - 0.0004005 46.0
CMS1_k127_906846_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1302.0
CMS1_k127_906846_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1210.0
CMS1_k127_906846_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 314.0
CMS1_k127_906846_11 pfam nmd3 K07562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002025 286.0
CMS1_k127_906846_12 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000225 267.0
CMS1_k127_906846_13 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007379 250.0
CMS1_k127_906846_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002157 251.0
CMS1_k127_906846_15 - K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000003194 264.0
CMS1_k127_906846_16 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000005371 228.0
CMS1_k127_906846_17 Located on the platform of the 30S subunit K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000001348 223.0
CMS1_k127_906846_18 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000001716 192.0
CMS1_k127_906846_19 transcription termination protein NusA K02600 - - 0.0000000000000000000000000000000000000000000000000007917 186.0
CMS1_k127_906846_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 4.189e-312 965.0
CMS1_k127_906846_20 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000002784 177.0
CMS1_k127_906846_21 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000009434 123.0
CMS1_k127_906846_22 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.00000000000000000000000001144 111.0
CMS1_k127_906846_23 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.000000000000000000000003431 104.0
CMS1_k127_906846_3 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 2.38e-243 762.0
CMS1_k127_906846_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 5.231e-232 724.0
CMS1_k127_906846_5 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 569.0
CMS1_k127_906846_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 503.0
CMS1_k127_906846_7 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 373.0
CMS1_k127_906846_8 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 331.0
CMS1_k127_906846_9 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 315.0
CMS1_k127_908821_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 4.861e-288 902.0
CMS1_k127_908821_1 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000008475 211.0
CMS1_k127_908821_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000006793 206.0
CMS1_k127_908821_3 Functions by promoting the formation of the first peptide bond K03263 - - 0.0000000000000000000000000000000000000000000000000001179 188.0
CMS1_k127_908821_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000002859 152.0
CMS1_k127_908821_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000004691 104.0
CMS1_k127_908821_6 Psort location Cytoplasmic, score K01163 - - 0.00000000000000008396 91.0
CMS1_k127_908821_7 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000944 85.0
CMS1_k127_908821_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000284 66.0
CMS1_k127_908821_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000003725 57.0
CMS1_k127_920719_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 1.086e-270 850.0
CMS1_k127_920719_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 579.0
CMS1_k127_920719_10 PFAM TM2 domain containing protein K03686 - - 0.0001777 46.0
CMS1_k127_920719_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 509.0
CMS1_k127_920719_3 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 400.0
CMS1_k127_920719_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 351.0
CMS1_k127_920719_5 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000007351 222.0
CMS1_k127_920719_6 cell wall organization - - - 0.0000000000000000000000000000000000000000000000004899 198.0
CMS1_k127_920719_7 KEOPS complex Cgi121-like subunit K09119 - - 0.00000000000000000000000000000000000004982 148.0
CMS1_k127_920719_8 Belongs to the UPF0216 family K09737 - - 0.000000000000006625 79.0
CMS1_k127_920719_9 hmm pf01694 - - - 0.00000000000001297 82.0
CMS1_k127_935167_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 462.0
CMS1_k127_935167_1 TIGRFAM 2-methylcitrate synthase citrate synthase II K01647,K01659 - 2.3.3.1,2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 374.0
CMS1_k127_935167_10 Carbon-nitrogen hydrolase K13101,K13566 GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006082,GO:0006107,GO:0006520,GO:0006528,GO:0006541,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0009064,GO:0009066,GO:0009987,GO:0012505,GO:0015630,GO:0016192,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032787,GO:0032940,GO:0034641,GO:0034774,GO:0035580,GO:0036230,GO:0042119,GO:0042581,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0043603,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044430,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046903,GO:0050152,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0070820,GO:0071704,GO:0097708,GO:0099503,GO:1901564,GO:1901605,GO:1904724 3.5.1.3 0.0002999 44.0
CMS1_k127_935167_2 PINc domain ribonuclease K09006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008337 335.0
CMS1_k127_935167_3 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 329.0
CMS1_k127_935167_4 response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 311.0
CMS1_k127_935167_5 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002571 279.0
CMS1_k127_935167_6 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000329 263.0
CMS1_k127_935167_7 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000002464 194.0
CMS1_k127_935167_8 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000004443 119.0
CMS1_k127_935167_9 - - - - 0.00000000000000000000000000064 115.0
CMS1_k127_937264_0 protein contain chitin-binding domain type 3 K01179 - 3.2.1.4 0.00000000000000000000000000000000002181 156.0
CMS1_k127_937264_1 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.0000000000000000000000000000000315 146.0
CMS1_k127_958328_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1533.0
CMS1_k127_958328_1 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008255 282.0
CMS1_k127_958328_2 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002957 283.0
CMS1_k127_958328_3 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000008456 237.0
CMS1_k127_958328_4 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000003161 238.0
CMS1_k127_958328_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000004551 150.0
CMS1_k127_958328_6 denitrification pathway - - - 0.0000000000000000000000000000006178 132.0
CMS1_k127_958328_7 - - - - 0.00000000000000000000000000005582 127.0
CMS1_k127_967022_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1311.0
CMS1_k127_967022_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 - - 1.635e-259 814.0
CMS1_k127_967022_10 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 290.0
CMS1_k127_967022_11 regulatory protein, arsR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008844 258.0
CMS1_k127_967022_12 methyltransferase activity K00577 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000001135 218.0
CMS1_k127_967022_13 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000005261 213.0
CMS1_k127_967022_14 serine-type peptidase activity K04773 - - 0.000000000000000000000000000000000000000000000000000000000008857 217.0
CMS1_k127_967022_15 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000001473 196.0
CMS1_k127_967022_16 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000002539 179.0
CMS1_k127_967022_17 Non-histone chromosomal protein MC1 - - - 0.000000000000000000000000000000000000000002122 156.0
CMS1_k127_967022_18 MTH865-like family - - - 0.000000000000000000000000000000002568 130.0
CMS1_k127_967022_19 metal ion binding - - - 0.0000000000000000000000000001674 119.0
CMS1_k127_967022_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 7.536e-199 626.0
CMS1_k127_967022_20 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000000003562 113.0
CMS1_k127_967022_21 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000005318 109.0
CMS1_k127_967022_22 COG1226 Kef-type K transport systems - - - 0.0000000000000000000000001049 119.0
CMS1_k127_967022_23 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain - - - 0.0000000000000000000004618 110.0
CMS1_k127_967022_24 Domain of unknown function (DUF1858) - - - 0.000000000000000003764 85.0
CMS1_k127_967022_25 COG0607 Rhodanese-related sulfurtransferase K03406,K21028 - 2.8.1.11 0.000000000000005491 79.0
CMS1_k127_967022_26 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.00000002713 57.0
CMS1_k127_967022_3 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 605.0
CMS1_k127_967022_4 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 588.0
CMS1_k127_967022_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 514.0
CMS1_k127_967022_6 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 453.0
CMS1_k127_967022_7 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 380.0
CMS1_k127_967022_8 Domain of unknown function DUF128 K21640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 302.0
CMS1_k127_967022_9 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 299.0
CMS1_k127_971764_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436,K14126,K17993 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 544.0
CMS1_k127_971764_1 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 480.0
CMS1_k127_971764_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 349.0
CMS1_k127_971764_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001055 271.0
CMS1_k127_973513_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000009974 214.0
CMS1_k127_973513_1 PBS lyase HEAT-like repeat - - - 0.0000002042 64.0
CMS1_k127_986777_0 Uncharacterized protein conserved in archaea (DUF2193) - - - 1.923e-241 754.0
CMS1_k127_986777_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009507 606.0
CMS1_k127_986777_10 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.00000000000000000000006746 111.0
CMS1_k127_986777_11 - - - - 0.0000000000001206 78.0
CMS1_k127_986777_12 - - - - 0.0000000003702 67.0
CMS1_k127_986777_13 Belongs to the ompA family K03286,K20276 - - 0.000001913 59.0
CMS1_k127_986777_14 Phospholipase_D-nuclease N-terminal - - - 0.0003245 49.0
CMS1_k127_986777_2 PFAM AIR synthase related protein K07123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 453.0
CMS1_k127_986777_3 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 360.0
CMS1_k127_986777_4 Major intrinsic protein K02440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 319.0
CMS1_k127_986777_5 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008668 277.0
CMS1_k127_986777_6 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001418 267.0
CMS1_k127_986777_7 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000001178 243.0
CMS1_k127_986777_8 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000000000000000000000000000000001745 247.0
CMS1_k127_986777_9 Prokaryotic homologs of the JAB domain - - - 0.00000000000000000000000000000000000000000000006489 171.0
CMS1_k127_990078_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 6.127e-195 628.0
CMS1_k127_990078_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000003762 180.0
CMS1_k127_990078_2 - - - - 0.000000000000000000006122 100.0
CMS1_k127_990078_3 integral membrane protein - - - 0.00000000000005054 79.0
CMS1_k127_990078_4 META domain - - - 0.00000007044 56.0
CMS1_k127_991104_0 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008893 524.0
CMS1_k127_991104_1 plastoquinone (Complex I) K12141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006483 508.0
CMS1_k127_991104_10 AMP binding - - - 0.0005002 48.0
CMS1_k127_991104_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 366.0
CMS1_k127_991104_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000005396 234.0
CMS1_k127_991104_4 - - - - 0.00000000000000000000000000000000000000008557 157.0
CMS1_k127_991104_5 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) K12143 - - 0.000000000000000000000006119 104.0
CMS1_k127_991104_6 - - - - 0.00000000000000000000000716 115.0
CMS1_k127_991104_7 Hydrogenase 4 membrane K12140 - - 0.00000000004302 63.0
CMS1_k127_991104_8 - - - - 0.00000007631 61.0
CMS1_k127_991104_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000001373 50.0