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Overview

ID MAG00363
Name CMS1_bin.49
Sample SMP0010
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order SMXQ01
Family SMXQ01
Genus WHSO01
Species
Assembly information
Completeness (%) 72.12
Contamination (%) 0.25
GC content (%) 66.0
N50 (bp) 48,180
Genome size (bp) 2,098,871

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1920

Gene name Description KEGG GOs EC E-value Score Sequence
CMS1_k127_1015263_0 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 3.958e-241 760.0
CMS1_k127_1015263_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 612.0
CMS1_k127_1015263_10 COG3264 Small-conductance mechanosensitive channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 394.0
CMS1_k127_1015263_11 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 388.0
CMS1_k127_1015263_12 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 389.0
CMS1_k127_1015263_13 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 390.0
CMS1_k127_1015263_14 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 368.0
CMS1_k127_1015263_15 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 353.0
CMS1_k127_1015263_16 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 328.0
CMS1_k127_1015263_17 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 329.0
CMS1_k127_1015263_18 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 318.0
CMS1_k127_1015263_19 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 312.0
CMS1_k127_1015263_2 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 590.0
CMS1_k127_1015263_20 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 300.0
CMS1_k127_1015263_21 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 298.0
CMS1_k127_1015263_22 CorA-like Mg2+ transporter protein K03284,K16074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 309.0
CMS1_k127_1015263_23 Acid phosphatase homologues K12978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008443 279.0
CMS1_k127_1015263_24 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001481 261.0
CMS1_k127_1015263_25 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000005435 233.0
CMS1_k127_1015263_26 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000002043 223.0
CMS1_k127_1015263_27 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000001509 228.0
CMS1_k127_1015263_28 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000000000000000000001144 192.0
CMS1_k127_1015263_29 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000002497 186.0
CMS1_k127_1015263_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 539.0
CMS1_k127_1015263_30 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000003827 172.0
CMS1_k127_1015263_31 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000001721 164.0
CMS1_k127_1015263_32 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000000000138 150.0
CMS1_k127_1015263_33 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000021 145.0
CMS1_k127_1015263_34 - - - - 0.0000000000000000000000000000000009748 139.0
CMS1_k127_1015263_35 Transcriptional regulator K13771 - - 0.00000000000000000000000000001643 124.0
CMS1_k127_1015263_36 ArsC family K00537 - 1.20.4.1 0.0000000000000000000000000006275 117.0
CMS1_k127_1015263_37 Short C-terminal domain K08982 - - 0.00000000000005417 76.0
CMS1_k127_1015263_38 - - - - 0.00004649 48.0
CMS1_k127_1015263_4 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 539.0
CMS1_k127_1015263_5 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 501.0
CMS1_k127_1015263_6 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 505.0
CMS1_k127_1015263_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 496.0
CMS1_k127_1015263_8 Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 478.0
CMS1_k127_1015263_9 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 420.0
CMS1_k127_1063909_0 PFAM Penicillin binding protein transpeptidase domain K05366 - 2.4.1.129,3.4.16.4 1.04e-322 1006.0
CMS1_k127_1063909_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 5.335e-308 973.0
CMS1_k127_1063909_10 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 480.0
CMS1_k127_1063909_11 CoA binding domain K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 478.0
CMS1_k127_1063909_12 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 452.0
CMS1_k127_1063909_13 ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 452.0
CMS1_k127_1063909_14 Zn-dependent protease, contains TPR repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 441.0
CMS1_k127_1063909_15 Belongs to the UbiD family K01612 - 4.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 416.0
CMS1_k127_1063909_16 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 400.0
CMS1_k127_1063909_17 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 360.0
CMS1_k127_1063909_18 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 356.0
CMS1_k127_1063909_19 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007508 329.0
CMS1_k127_1063909_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 8.596e-210 687.0
CMS1_k127_1063909_20 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 325.0
CMS1_k127_1063909_21 serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 315.0
CMS1_k127_1063909_22 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 301.0
CMS1_k127_1063909_23 Maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 284.0
CMS1_k127_1063909_24 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003967 282.0
CMS1_k127_1063909_25 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003033 278.0
CMS1_k127_1063909_26 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001231 276.0
CMS1_k127_1063909_27 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003955 271.0
CMS1_k127_1063909_28 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000185 273.0
CMS1_k127_1063909_29 Pfam Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002277 265.0
CMS1_k127_1063909_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 601.0
CMS1_k127_1063909_30 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000001258 247.0
CMS1_k127_1063909_31 transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000000000000000000000000000001578 232.0
CMS1_k127_1063909_32 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000001265 239.0
CMS1_k127_1063909_33 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000811 211.0
CMS1_k127_1063909_34 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000009245 225.0
CMS1_k127_1063909_35 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000007614 196.0
CMS1_k127_1063909_36 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000006142 204.0
CMS1_k127_1063909_37 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000003867 198.0
CMS1_k127_1063909_38 Ferredoxin K04755 - - 0.00000000000000000000000000000000000000000000000001619 181.0
CMS1_k127_1063909_39 Ketosteroid isomerase-related protein - - - 0.000000000000000000000000000000000000000000000004636 179.0
CMS1_k127_1063909_4 Protein of unknown function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 568.0
CMS1_k127_1063909_40 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000001235 167.0
CMS1_k127_1063909_41 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000004148 151.0
CMS1_k127_1063909_42 - - - - 0.00000000000000000000000000003206 116.0
CMS1_k127_1063909_43 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000009295 117.0
CMS1_k127_1063909_44 - - - - 0.00000000000000000000002565 107.0
CMS1_k127_1063909_46 oxidation-reduction process - - - 0.00000000000000000004093 97.0
CMS1_k127_1063909_47 Sporulation related domain - - - 0.000000000000001327 87.0
CMS1_k127_1063909_48 - - - - 0.0000000911 59.0
CMS1_k127_1063909_49 EF-hand, calcium binding motif - - - 0.0000005488 59.0
CMS1_k127_1063909_50 Cysteine dioxygenase type I - - - 0.000001086 57.0
CMS1_k127_1063909_51 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0003683 45.0
CMS1_k127_1063909_6 ethanolamine utilization protein K04019 GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 520.0
CMS1_k127_1063909_7 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 511.0
CMS1_k127_1063909_8 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 502.0
CMS1_k127_1063909_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 480.0
CMS1_k127_1076352_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 518.0
CMS1_k127_1076352_1 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 464.0
CMS1_k127_1090081_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 8.765e-244 776.0
CMS1_k127_1090081_1 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 GO:0003674,GO:0003824,GO:0004474,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006097,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044464,GO:0046487,GO:0046912,GO:0071704 2.3.3.9 2.3e-228 719.0
CMS1_k127_1090081_10 Asparaginase K01424,K22278 - 3.5.1.1,3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000226 271.0
CMS1_k127_1090081_11 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000003808 227.0
CMS1_k127_1090081_12 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000007954 179.0
CMS1_k127_1090081_13 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000009246 89.0
CMS1_k127_1090081_2 PFAM AMP-dependent synthetase and ligase - - - 2.309e-220 696.0
CMS1_k127_1090081_3 Polysaccharide biosynthesis protein K01784,K12448 - 5.1.3.2,5.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 528.0
CMS1_k127_1090081_4 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 499.0
CMS1_k127_1090081_5 Tripartite tricarboxylate transporter TctA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 490.0
CMS1_k127_1090081_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 473.0
CMS1_k127_1090081_7 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 374.0
CMS1_k127_1090081_8 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 331.0
CMS1_k127_1090081_9 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 310.0
CMS1_k127_1113381_0 COG0367 Asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 7.954e-226 718.0
CMS1_k127_1113381_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 1.345e-194 615.0
CMS1_k127_1113381_10 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 296.0
CMS1_k127_1113381_11 FAD dependent oxidoreductase K13796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007839 266.0
CMS1_k127_1113381_12 Mandelate racemase muconate lactonizing enzyme - - - 0.00000000000000000000000000000000000000000000000000000001141 211.0
CMS1_k127_1113381_13 methionine biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000002106 212.0
CMS1_k127_1113381_14 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000002898 204.0
CMS1_k127_1113381_15 Protein of unknown function (DUF1698) - - - 0.0000000000000000000000000000000000000007892 160.0
CMS1_k127_1113381_16 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000000001042 159.0
CMS1_k127_1113381_17 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000001471 139.0
CMS1_k127_1113381_18 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000006344 137.0
CMS1_k127_1113381_19 TIGRFAM Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000107 74.0
CMS1_k127_1113381_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 496.0
CMS1_k127_1113381_20 PFAM Major Facilitator Superfamily - - - 0.000184 54.0
CMS1_k127_1113381_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 368.0
CMS1_k127_1113381_4 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 383.0
CMS1_k127_1113381_5 long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 346.0
CMS1_k127_1113381_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 344.0
CMS1_k127_1113381_7 TOBE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 329.0
CMS1_k127_1113381_8 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005167 334.0
CMS1_k127_1113381_9 Capsule synthesis protein K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 325.0
CMS1_k127_1135072_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1440.0
CMS1_k127_1135072_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1199.0
CMS1_k127_1135072_10 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003173 271.0
CMS1_k127_1135072_11 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003492 282.0
CMS1_k127_1135072_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001106 267.0
CMS1_k127_1135072_13 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003563 273.0
CMS1_k127_1135072_14 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004191 276.0
CMS1_k127_1135072_15 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007917 258.0
CMS1_k127_1135072_16 PFAM amidohydrolase 2 K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000004057 251.0
CMS1_k127_1135072_17 Dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000009013 244.0
CMS1_k127_1135072_18 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000002732 223.0
CMS1_k127_1135072_19 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000003459 216.0
CMS1_k127_1135072_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 1.692e-292 911.0
CMS1_k127_1135072_20 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000001297 205.0
CMS1_k127_1135072_21 PFAM Glutathione S-transferase domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000001944 209.0
CMS1_k127_1135072_22 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000001037 201.0
CMS1_k127_1135072_23 Bacterial transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000001662 192.0
CMS1_k127_1135072_24 Rhomboid family - - - 0.0000000000000000000000000000000000000000000005397 183.0
CMS1_k127_1135072_25 - - - - 0.0000000000000000000000000000000000000004509 154.0
CMS1_k127_1135072_26 Amidohydrolase K07045 - - 0.0000000000000000000000000000000001461 146.0
CMS1_k127_1135072_27 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000001028 118.0
CMS1_k127_1135072_28 SOS response K14160 - - 0.000000000000000000000000003801 121.0
CMS1_k127_1135072_29 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000001184 101.0
CMS1_k127_1135072_3 glutamine synthetase K01915 - 6.3.1.2 2.441e-247 771.0
CMS1_k127_1135072_30 YCII-related domain K09780 - - 0.00000000001639 72.0
CMS1_k127_1135072_31 Flp/Fap pilin component K02651 - - 0.0000000004938 63.0
CMS1_k127_1135072_32 - - - - 0.000001406 57.0
CMS1_k127_1135072_4 Belongs to the TPP enzyme family K01576,K01652 - 2.2.1.6,4.1.1.7 1.666e-198 645.0
CMS1_k127_1135072_5 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 543.0
CMS1_k127_1135072_6 Pyrogallol hydroxytransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 362.0
CMS1_k127_1135072_7 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007623 358.0
CMS1_k127_1135072_8 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 338.0
CMS1_k127_1135072_9 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 331.0
CMS1_k127_1198597_0 AcrB/AcrD/AcrF family K03296,K07788,K07789,K21133 - - 0.0 1215.0
CMS1_k127_1198597_1 acyl-CoA dehydrogenase K06445 - - 6.766e-313 974.0
CMS1_k127_1198597_10 ABC-type multidrug transport system, ATPase and permease K06147 - - 1.301e-232 736.0
CMS1_k127_1198597_100 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000001534 191.0
CMS1_k127_1198597_101 PFAM Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B - - - 0.0000000000000000000000000000000000000000000000000002034 207.0
CMS1_k127_1198597_102 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000002431 190.0
CMS1_k127_1198597_103 PFAM Amidohydrolase 2 - - - 0.00000000000000000000000000000000000000000000000000672 195.0
CMS1_k127_1198597_104 Class II aldolase K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000001073 184.0
CMS1_k127_1198597_105 Zinc-dependent metalloprotease - - - 0.000000000000000000000000000000000000000000000007243 182.0
CMS1_k127_1198597_106 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000001363 183.0
CMS1_k127_1198597_107 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935,K02169 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.197,6.3.3.3 0.0000000000000000000000000000000000000000000001973 179.0
CMS1_k127_1198597_108 6-pyruvoyl tetrahydropterin synthase - - - 0.000000000000000000000000000000000000000000003764 167.0
CMS1_k127_1198597_109 Cytochrome c, class I K08738 - - 0.000000000000000000000000000000000000000000006376 168.0
CMS1_k127_1198597_11 Belongs to the ABC transporter superfamily K13896 - - 2.042e-232 731.0
CMS1_k127_1198597_110 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000004108 168.0
CMS1_k127_1198597_111 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.000000000000000000000000000000000000000005635 163.0
CMS1_k127_1198597_112 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000008129 160.0
CMS1_k127_1198597_113 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000009842 143.0
CMS1_k127_1198597_114 Response regulator receiver - - - 0.0000000000000000000000000000000008978 136.0
CMS1_k127_1198597_115 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000001277 131.0
CMS1_k127_1198597_116 Predicted integral membrane protein (DUF2282) - - - 0.00000000000000000000000000000002772 130.0
CMS1_k127_1198597_117 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000008579 126.0
CMS1_k127_1198597_118 Cytochrome B561 K12262 - - 0.00000000000000000000000001586 117.0
CMS1_k127_1198597_119 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000001429 109.0
CMS1_k127_1198597_12 enoyl-CoA hydratase isomerase K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 8.313e-224 712.0
CMS1_k127_1198597_120 Bacterial DNA-binding protein - - - 0.000000000000000000000004597 105.0
CMS1_k127_1198597_121 COG1846 Transcriptional regulators - - - 0.00000000000000000000001696 104.0
CMS1_k127_1198597_122 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.0000000000000000000000377 106.0
CMS1_k127_1198597_123 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000001073 112.0
CMS1_k127_1198597_124 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000001277 112.0
CMS1_k127_1198597_125 Cupin domain - - - 0.0000000000000000000002499 102.0
CMS1_k127_1198597_126 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000004458 102.0
CMS1_k127_1198597_127 ABC-type nitrate sulfonate bicarbonate transport - - - 0.0000000000000000002596 99.0
CMS1_k127_1198597_128 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000004702 90.0
CMS1_k127_1198597_129 Hydantoin racemase K16841 - 5.1.99.3 0.000000000000000005054 94.0
CMS1_k127_1198597_13 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.506e-212 673.0
CMS1_k127_1198597_130 Bacterial extracellular solute-binding protein - - - 0.0000000000000001175 92.0
CMS1_k127_1198597_131 - - - - 0.00000000000002303 83.0
CMS1_k127_1198597_132 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000002992 82.0
CMS1_k127_1198597_133 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K11210 - - 0.00000000001075 71.0
CMS1_k127_1198597_134 Glyoxalase-like domain K07104 - 1.13.11.2 0.00000000006922 68.0
CMS1_k127_1198597_135 ankyrin repeat K06867,K08738 - - 0.00000000007689 69.0
CMS1_k127_1198597_136 - - - - 0.00000005188 61.0
CMS1_k127_1198597_137 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.00008953 53.0
CMS1_k127_1198597_138 secretion pathway protein K02453 - - 0.0002371 53.0
CMS1_k127_1198597_139 TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family K02051,K15553 - - 0.0006493 51.0
CMS1_k127_1198597_14 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 4.255e-195 619.0
CMS1_k127_1198597_15 cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008053 613.0
CMS1_k127_1198597_16 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 594.0
CMS1_k127_1198597_17 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 571.0
CMS1_k127_1198597_18 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 561.0
CMS1_k127_1198597_19 Phosphofructokinase K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 525.0
CMS1_k127_1198597_2 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 3.096e-277 869.0
CMS1_k127_1198597_20 transport system, permease component K13895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 513.0
CMS1_k127_1198597_21 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 522.0
CMS1_k127_1198597_22 transport system, permease component K13894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 513.0
CMS1_k127_1198597_23 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 488.0
CMS1_k127_1198597_24 Glucose / Sorbosone dehydrogenase K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009055 477.0
CMS1_k127_1198597_25 Aminotransferase class-III K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 484.0
CMS1_k127_1198597_26 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 477.0
CMS1_k127_1198597_27 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 438.0
CMS1_k127_1198597_28 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 439.0
CMS1_k127_1198597_29 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 407.0
CMS1_k127_1198597_3 phosphatase K07093 - - 3.731e-275 860.0
CMS1_k127_1198597_30 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 391.0
CMS1_k127_1198597_31 COG0655 Multimeric flavodoxin WrbA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 382.0
CMS1_k127_1198597_32 FAD binding domain K13796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 392.0
CMS1_k127_1198597_33 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 363.0
CMS1_k127_1198597_34 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 367.0
CMS1_k127_1198597_35 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 362.0
CMS1_k127_1198597_36 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 358.0
CMS1_k127_1198597_37 Amidohydrolase K10220 - 4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 355.0
CMS1_k127_1198597_38 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 353.0
CMS1_k127_1198597_39 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 349.0
CMS1_k127_1198597_4 Tripartite tricarboxylate transporter TctA family - - - 1.934e-262 825.0
CMS1_k127_1198597_40 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 339.0
CMS1_k127_1198597_41 Cytidylyltransferase K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 338.0
CMS1_k127_1198597_42 Rieske (2fe-2S) K15060 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 334.0
CMS1_k127_1198597_43 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 333.0
CMS1_k127_1198597_44 Rieske (2fe-2S) K15060 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 332.0
CMS1_k127_1198597_45 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 338.0
CMS1_k127_1198597_46 PFAM ABC transporter K02010,K02017,K02062,K10112,K10199,K17314 - 3.6.3.29,3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 328.0
CMS1_k127_1198597_47 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 320.0
CMS1_k127_1198597_48 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008064 319.0
CMS1_k127_1198597_49 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 320.0
CMS1_k127_1198597_5 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 1.008e-248 774.0
CMS1_k127_1198597_50 ABC-type Fe3 transport system permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 330.0
CMS1_k127_1198597_51 Transmembrane secretion effector K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 323.0
CMS1_k127_1198597_52 conserved protein (DUF2260) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 316.0
CMS1_k127_1198597_53 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 311.0
CMS1_k127_1198597_54 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 303.0
CMS1_k127_1198597_55 COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 304.0
CMS1_k127_1198597_56 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 307.0
CMS1_k127_1198597_57 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 304.0
CMS1_k127_1198597_58 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 300.0
CMS1_k127_1198597_59 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 299.0
CMS1_k127_1198597_6 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 4.401e-245 779.0
CMS1_k127_1198597_60 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 294.0
CMS1_k127_1198597_61 ABC-type Fe3 transport system permease component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 303.0
CMS1_k127_1198597_62 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009735 299.0
CMS1_k127_1198597_63 GTP cyclohydrolase II K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 294.0
CMS1_k127_1198597_64 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000094 283.0
CMS1_k127_1198597_65 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001894 278.0
CMS1_k127_1198597_66 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001576 287.0
CMS1_k127_1198597_67 proline dipeptidase activity K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001167 269.0
CMS1_k127_1198597_68 COG1985 Pyrimidine reductase, riboflavin biosynthesis K00082 - 1.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000002203 267.0
CMS1_k127_1198597_69 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002284 267.0
CMS1_k127_1198597_7 Rieske-like [2Fe-2S] domain - - - 4.343e-244 768.0
CMS1_k127_1198597_70 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002276 261.0
CMS1_k127_1198597_71 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000002792 256.0
CMS1_k127_1198597_72 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002546 261.0
CMS1_k127_1198597_73 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000001761 260.0
CMS1_k127_1198597_74 Taurine catabolism dioxygenase TauD, TfdA family K22303 - - 0.000000000000000000000000000000000000000000000000000000000000000000001961 245.0
CMS1_k127_1198597_75 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002743 235.0
CMS1_k127_1198597_76 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000002919 241.0
CMS1_k127_1198597_77 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000002923 241.0
CMS1_k127_1198597_78 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000003885 239.0
CMS1_k127_1198597_79 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000005618 231.0
CMS1_k127_1198597_8 Glycosyl hydrolases family 15 - - - 1.329e-242 764.0
CMS1_k127_1198597_80 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000299 229.0
CMS1_k127_1198597_81 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000009665 229.0
CMS1_k127_1198597_82 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000019 222.0
CMS1_k127_1198597_83 - - - - 0.0000000000000000000000000000000000000000000000000000000000001304 222.0
CMS1_k127_1198597_84 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001454 227.0
CMS1_k127_1198597_85 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000003048 217.0
CMS1_k127_1198597_86 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001361 222.0
CMS1_k127_1198597_87 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000002928 223.0
CMS1_k127_1198597_88 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000000000000000000000000003398 216.0
CMS1_k127_1198597_89 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000000000004207 214.0
CMS1_k127_1198597_9 COG4166 ABC-type oligopeptide transport system, periplasmic component K13893 - - 1.418e-241 764.0
CMS1_k127_1198597_90 Aldolase - - - 0.00000000000000000000000000000000000000000000000000000000005985 213.0
CMS1_k127_1198597_91 Class II aldolase K18613 GO:0003674,GO:0003824,GO:0005488,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009111,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0017144,GO:0030145,GO:0034641,GO:0042365,GO:0042737,GO:0042816,GO:0042820,GO:0043167,GO:0043169,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0047431,GO:0071704,GO:0072524,GO:0072526,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 4.1.1.51 0.0000000000000000000000000000000000000000000000000000000002864 211.0
CMS1_k127_1198597_92 DoxX family K15977 - - 0.0000000000000000000000000000000000000000000000000000000006889 207.0
CMS1_k127_1198597_93 iron ion binding - - - 0.000000000000000000000000000000000000000000000000000000001944 209.0
CMS1_k127_1198597_94 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000003796 218.0
CMS1_k127_1198597_95 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000734 208.0
CMS1_k127_1198597_96 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000004519 209.0
CMS1_k127_1198597_97 Putative DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000001965 211.0
CMS1_k127_1198597_98 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000000000000000000871 199.0
CMS1_k127_1198597_99 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000004299 204.0
CMS1_k127_1223924_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1067.0
CMS1_k127_1223924_1 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 4.884e-220 689.0
CMS1_k127_1223924_2 Leucyl/phenylalanyl-tRNA protein transferase K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 265.0
CMS1_k127_1223924_3 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001259 262.0
CMS1_k127_1223924_4 COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000001812 158.0
CMS1_k127_1223924_5 NADH ubiquinone oxidoreductase 17.2 kD subunit - - - 0.0000000000000000000000000000000000000002834 155.0
CMS1_k127_1223924_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000001394 143.0
CMS1_k127_1223924_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000008445 128.0
CMS1_k127_1245929_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1491.0
CMS1_k127_1245929_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1239.0
CMS1_k127_1245929_10 deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 514.0
CMS1_k127_1245929_11 ATPase (AAA K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 405.0
CMS1_k127_1245929_12 COG1840 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 392.0
CMS1_k127_1245929_13 PFAM Endonuclease Exonuclease phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 367.0
CMS1_k127_1245929_14 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 370.0
CMS1_k127_1245929_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 361.0
CMS1_k127_1245929_16 SecD/SecF GG Motif K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 359.0
CMS1_k127_1245929_17 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 340.0
CMS1_k127_1245929_18 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 297.0
CMS1_k127_1245929_19 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 301.0
CMS1_k127_1245929_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 9.194e-305 943.0
CMS1_k127_1245929_20 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 292.0
CMS1_k127_1245929_21 COG1994 Zn-dependent proteases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000806 283.0
CMS1_k127_1245929_22 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000134 277.0
CMS1_k127_1245929_23 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000001707 270.0
CMS1_k127_1245929_24 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000001957 240.0
CMS1_k127_1245929_25 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000002294 235.0
CMS1_k127_1245929_26 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000001501 225.0
CMS1_k127_1245929_27 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000386 223.0
CMS1_k127_1245929_28 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00256,K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000004228 223.0
CMS1_k127_1245929_29 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000001374 206.0
CMS1_k127_1245929_3 Arginyl-tRNA synthetase K01887 - 6.1.1.19 3.348e-257 804.0
CMS1_k127_1245929_30 COG0346 Lactoylglutathione lyase and related lyases K07032 - - 0.00000000000000000000000000000000000000000000000302 177.0
CMS1_k127_1245929_31 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000009761 181.0
CMS1_k127_1245929_32 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000001999 158.0
CMS1_k127_1245929_33 Preprotein translocase subunit YajC K03210 - - 0.000000000000000000000000000000000004536 141.0
CMS1_k127_1245929_34 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000000000004624 134.0
CMS1_k127_1245929_35 Sporulation related domain - - - 0.000000000000000000000000000000003562 139.0
CMS1_k127_1245929_36 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000001509 107.0
CMS1_k127_1245929_37 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000006819 96.0
CMS1_k127_1245929_38 Squalene/phytoene synthase K21679 - 4.2.3.156 0.00000000000000001402 94.0
CMS1_k127_1245929_39 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000003735 81.0
CMS1_k127_1245929_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 5.689e-249 788.0
CMS1_k127_1245929_40 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000001227 62.0
CMS1_k127_1245929_41 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0001393 52.0
CMS1_k127_1245929_5 inner membrane component K02011 - - 5.198e-216 684.0
CMS1_k127_1245929_6 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 4.899e-208 677.0
CMS1_k127_1245929_7 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 4.921e-201 637.0
CMS1_k127_1245929_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.081e-196 627.0
CMS1_k127_1245929_9 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 548.0
CMS1_k127_1448308_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1292.0
CMS1_k127_1448308_1 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 513.0
CMS1_k127_1448308_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 484.0
CMS1_k127_1448308_3 KR domain K03366 - 1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 327.0
CMS1_k127_1448308_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 310.0
CMS1_k127_1448308_5 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000008392 219.0
CMS1_k127_1448308_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000002983 178.0
CMS1_k127_1448308_7 Protein of unknown function (DUF3035) - - - 0.0000000000000000000000000000000000000003132 156.0
CMS1_k127_1448308_8 protein conserved in bacteria - - - 0.00000000000000000002244 97.0
CMS1_k127_1554776_0 Thiamine pyrophosphate enzyme, central domain - - - 3.945e-241 757.0
CMS1_k127_1554776_1 Belongs to the UbiD family K03182 - 4.1.1.98 2.159e-198 632.0
CMS1_k127_1554776_2 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 454.0
CMS1_k127_1554776_3 Belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 374.0
CMS1_k127_1554776_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 338.0
CMS1_k127_1554776_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 302.0
CMS1_k127_1554776_6 Predicted permease - - - 0.0000000000000000000000000000000000002973 148.0
CMS1_k127_1554776_7 Predicted permease - - - 0.000000000000000000002545 107.0
CMS1_k127_1812749_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1124.0
CMS1_k127_1812749_1 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 8.409e-227 715.0
CMS1_k127_1812749_10 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 386.0
CMS1_k127_1812749_11 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 377.0
CMS1_k127_1812749_12 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 379.0
CMS1_k127_1812749_13 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 366.0
CMS1_k127_1812749_14 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 352.0
CMS1_k127_1812749_15 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 348.0
CMS1_k127_1812749_16 Catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 336.0
CMS1_k127_1812749_17 Polyprenyl synthetase K00795 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 335.0
CMS1_k127_1812749_18 rRNA methylase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 334.0
CMS1_k127_1812749_19 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 330.0
CMS1_k127_1812749_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 602.0
CMS1_k127_1812749_20 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 328.0
CMS1_k127_1812749_21 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 336.0
CMS1_k127_1812749_22 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 305.0
CMS1_k127_1812749_23 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002773 276.0
CMS1_k127_1812749_24 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001537 284.0
CMS1_k127_1812749_25 Outer membrane efflux protein K12543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001453 282.0
CMS1_k127_1812749_26 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000002958 259.0
CMS1_k127_1812749_27 Universal stress protein UspA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001707 252.0
CMS1_k127_1812749_28 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001878 243.0
CMS1_k127_1812749_29 Flp pilus assembly protein RcpC/CpaB - - - 0.00000000000000000000000000000000000000000000000000000000000002621 227.0
CMS1_k127_1812749_3 5-aminolevulinic acid synthase K00643 - 2.3.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 569.0
CMS1_k127_1812749_30 Type II secretion system (T2SS), protein F - - - 0.00000000000000000000000000000000000000000000000000000000003022 217.0
CMS1_k127_1812749_31 Type II secretion system (T2SS), protein F - - - 0.0000000000000000000000000000000000000000000000000000004015 205.0
CMS1_k127_1812749_32 Pilus assembly protein - - - 0.00000000000000000000000000000000000000000000000000005223 202.0
CMS1_k127_1812749_33 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000002037 197.0
CMS1_k127_1812749_34 Protein of unknown function (DUF1194) - - - 0.00000000000000000000000000000000000000000000000003758 189.0
CMS1_k127_1812749_35 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000004407 187.0
CMS1_k127_1812749_36 Domain of unknown function (DUF4202) - - - 0.000000000000000000000000000000000000000000000005028 181.0
CMS1_k127_1812749_37 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000000106 160.0
CMS1_k127_1812749_38 - - - - 0.0000000000000000000000000000000000000000001102 163.0
CMS1_k127_1812749_39 Putative AphA-like transcriptional regulator - - - 0.00000000000000000000000000000000000000000139 164.0
CMS1_k127_1812749_4 Type II/IV secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 567.0
CMS1_k127_1812749_40 Amidohydrolase K07045 - - 0.000000000000000000000000000000000005238 153.0
CMS1_k127_1812749_41 Cupin - - - 0.00000000000000000000000000000003244 142.0
CMS1_k127_1812749_42 Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000003366 127.0
CMS1_k127_1812749_43 Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000005849 124.0
CMS1_k127_1812749_44 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000006387 112.0
CMS1_k127_1812749_45 Ndr family - - - 0.0000000000000000000000007894 114.0
CMS1_k127_1812749_46 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000005273 111.0
CMS1_k127_1812749_47 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000005605 93.0
CMS1_k127_1812749_48 peptidase K02278 - 3.4.23.43 0.0000000000000008652 85.0
CMS1_k127_1812749_49 peptidyl-tyrosine sulfation - - - 0.00000000000002502 87.0
CMS1_k127_1812749_5 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 551.0
CMS1_k127_1812749_50 Flp/Fap pilin component K02651 - - 0.000000000009105 68.0
CMS1_k127_1812749_52 - - - - 0.000000008705 63.0
CMS1_k127_1812749_53 Ribbon-helix-helix domain - - - 0.0000007907 61.0
CMS1_k127_1812749_54 HicA toxin of bacterial toxin-antitoxin, - - - 0.0008398 51.0
CMS1_k127_1812749_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 538.0
CMS1_k127_1812749_7 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 451.0
CMS1_k127_1812749_8 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 416.0
CMS1_k127_1812749_9 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 390.0
CMS1_k127_1928795_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.889e-212 677.0
CMS1_k127_1928795_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 600.0
CMS1_k127_1928795_10 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 423.0
CMS1_k127_1928795_11 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 379.0
CMS1_k127_1928795_12 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 376.0
CMS1_k127_1928795_13 PFAM Bile acid sodium symporter K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 358.0
CMS1_k127_1928795_14 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008853 368.0
CMS1_k127_1928795_15 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 320.0
CMS1_k127_1928795_16 FAD dependent oxidoreductase K13796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004641 269.0
CMS1_k127_1928795_17 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007231 276.0
CMS1_k127_1928795_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000248 269.0
CMS1_k127_1928795_19 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000001887 260.0
CMS1_k127_1928795_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009481 547.0
CMS1_k127_1928795_20 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002217 248.0
CMS1_k127_1928795_21 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000002696 237.0
CMS1_k127_1928795_22 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000001676 230.0
CMS1_k127_1928795_23 carboxylic ester hydrolase activity - GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000124 236.0
CMS1_k127_1928795_24 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000002683 224.0
CMS1_k127_1928795_25 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000002891 207.0
CMS1_k127_1928795_26 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000001197 197.0
CMS1_k127_1928795_27 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000001135 210.0
CMS1_k127_1928795_28 PFAM Glutathione S-transferase K11209 - - 0.00000000000000000000000000000000000000000000000000001329 197.0
CMS1_k127_1928795_29 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000006237 172.0
CMS1_k127_1928795_3 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 512.0
CMS1_k127_1928795_30 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000000000000000004428 165.0
CMS1_k127_1928795_31 - - - - 0.0000000000000000000000000000000000000001529 156.0
CMS1_k127_1928795_32 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000007625 159.0
CMS1_k127_1928795_33 - - - - 0.0000000000000000000000000000000000009384 145.0
CMS1_k127_1928795_34 Staphylococcal nuclease homologues - - - 0.00000000000000000000000000000000000121 144.0
CMS1_k127_1928795_35 - - - - 0.000000000000000000000000000000001553 136.0
CMS1_k127_1928795_36 Excinuclease ABC, C subunit K07461 - - 0.000000000000000000000000000000006869 129.0
CMS1_k127_1928795_37 - - - - 0.0000000000000000000000000000001591 142.0
CMS1_k127_1928795_38 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000002043 129.0
CMS1_k127_1928795_39 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000008822 130.0
CMS1_k127_1928795_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 523.0
CMS1_k127_1928795_40 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.0000000000000000000000000192 121.0
CMS1_k127_1928795_41 - - - - 0.00000000000000000000001575 102.0
CMS1_k127_1928795_42 Cache_2 - - - 0.0000000000000000000000164 107.0
CMS1_k127_1928795_43 BON domain - - - 0.00000000000000000000001961 103.0
CMS1_k127_1928795_44 COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.0000000000000000000001871 106.0
CMS1_k127_1928795_45 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000008653 100.0
CMS1_k127_1928795_46 Periplasmic Protein - GO:0003674,GO:0004857,GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0016020,GO:0019867,GO:0030234,GO:0030312,GO:0030313,GO:0031975,GO:0043086,GO:0044092,GO:0044462,GO:0044464,GO:0050790,GO:0060241,GO:0065007,GO:0065009,GO:0071944,GO:0098772 - 0.000000002826 63.0
CMS1_k127_1928795_47 Cysteine dioxygenase type I - - - 0.000000004462 68.0
CMS1_k127_1928795_48 - - - - 0.0000000197 57.0
CMS1_k127_1928795_49 - - - - 0.00001213 51.0
CMS1_k127_1928795_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 504.0
CMS1_k127_1928795_50 AraC-like ligand binding domain - - - 0.0007551 51.0
CMS1_k127_1928795_6 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 473.0
CMS1_k127_1928795_7 FMN-dependent dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 461.0
CMS1_k127_1928795_8 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 438.0
CMS1_k127_1928795_9 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 432.0
CMS1_k127_1949017_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1050.0
CMS1_k127_1949017_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.904e-257 808.0
CMS1_k127_1949017_10 Alanine dehydrogenase/PNT, N-terminal domain K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 475.0
CMS1_k127_1949017_11 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 459.0
CMS1_k127_1949017_12 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 442.0
CMS1_k127_1949017_13 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 431.0
CMS1_k127_1949017_14 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 429.0
CMS1_k127_1949017_15 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 430.0
CMS1_k127_1949017_16 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 399.0
CMS1_k127_1949017_17 COG3000 Sterol desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 307.0
CMS1_k127_1949017_18 Transmembrane secretion effector K08217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 314.0
CMS1_k127_1949017_19 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 309.0
CMS1_k127_1949017_2 Glycosyl transferase family group 2 - - - 1.553e-256 816.0
CMS1_k127_1949017_20 Transmembrane secretion effector K08217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 313.0
CMS1_k127_1949017_21 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001327 268.0
CMS1_k127_1949017_22 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002036 259.0
CMS1_k127_1949017_23 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000518 232.0
CMS1_k127_1949017_24 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000009195 232.0
CMS1_k127_1949017_25 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000004342 218.0
CMS1_k127_1949017_26 COQ9 K18587 - - 0.0000000000000000000000000000000000000000000000000000002283 201.0
CMS1_k127_1949017_27 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000007374 207.0
CMS1_k127_1949017_28 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000003981 195.0
CMS1_k127_1949017_29 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000006452 198.0
CMS1_k127_1949017_3 Oligopeptidase F K08602 - - 1.204e-240 757.0
CMS1_k127_1949017_30 Protein of unknown function (DUF1244) K09948 - - 0.000000000000000000000000000000000000005989 147.0
CMS1_k127_1949017_31 NAD NADP transhydrogenase alpha subunit K00324 GO:0008150,GO:0008152,GO:0055114 1.6.1.2 0.00000000000000000000000000000000000001711 148.0
CMS1_k127_1949017_32 Protein of unknown function (DUF2390) - - - 0.0000000000000000000000000002474 122.0
CMS1_k127_1949017_33 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000004327 110.0
CMS1_k127_1949017_34 cyclopropane-fatty-acyl-phospholipid synthase - - - 0.000000000000000000017 104.0
CMS1_k127_1949017_35 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000006538 79.0
CMS1_k127_1949017_36 protein conserved in bacteria K09987 - - 0.0000000007609 63.0
CMS1_k127_1949017_37 Protein of unknown function (DUF465) - - - 0.000001497 53.0
CMS1_k127_1949017_4 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.777e-230 722.0
CMS1_k127_1949017_5 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 4.889e-228 715.0
CMS1_k127_1949017_6 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 5.815e-211 663.0
CMS1_k127_1949017_7 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 9e-211 677.0
CMS1_k127_1949017_8 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 2.023e-198 635.0
CMS1_k127_1949017_9 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 570.0
CMS1_k127_2014226_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1309.0
CMS1_k127_2014226_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 7.791e-311 961.0
CMS1_k127_2014226_10 OsmC-like protein - - - 0.000000002622 68.0
CMS1_k127_2014226_11 Recombinase zinc beta ribbon domain K06400 - - 0.0000001465 53.0
CMS1_k127_2014226_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 5.266e-286 903.0
CMS1_k127_2014226_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 6.341e-243 757.0
CMS1_k127_2014226_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 542.0
CMS1_k127_2014226_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 330.0
CMS1_k127_2014226_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000003788 239.0
CMS1_k127_2014226_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000008374 179.0
CMS1_k127_2014226_8 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000003698 96.0
CMS1_k127_2014226_9 DDE domain - - - 0.000000000009521 66.0
CMS1_k127_2092957_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1043.0
CMS1_k127_2092957_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 2.369e-224 731.0
CMS1_k127_2092957_10 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000288 264.0
CMS1_k127_2092957_11 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001514 270.0
CMS1_k127_2092957_12 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008489 270.0
CMS1_k127_2092957_13 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000001421 246.0
CMS1_k127_2092957_14 Glycosyl transferase group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005571 246.0
CMS1_k127_2092957_15 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000007662 218.0
CMS1_k127_2092957_16 Thioredoxin - - - 0.000000000000000000000000000000000000000000000003326 181.0
CMS1_k127_2092957_17 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000003852 180.0
CMS1_k127_2092957_18 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000005891 163.0
CMS1_k127_2092957_19 PFAM glycine cleavage T protein (aminomethyl transferase) K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.10 0.0000000000000000000000000000000000002132 143.0
CMS1_k127_2092957_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 599.0
CMS1_k127_2092957_20 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000003593 140.0
CMS1_k127_2092957_21 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000000000000000000000003887 110.0
CMS1_k127_2092957_22 Protein of unknown function (DUF721) - - - 0.00000000000000000000004405 115.0
CMS1_k127_2092957_23 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000004814 101.0
CMS1_k127_2092957_24 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000002215 97.0
CMS1_k127_2092957_3 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 523.0
CMS1_k127_2092957_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 429.0
CMS1_k127_2092957_5 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 431.0
CMS1_k127_2092957_6 COG1194 A G-specific DNA glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 398.0
CMS1_k127_2092957_7 Sodium/hydrogen exchanger family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 373.0
CMS1_k127_2092957_8 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 318.0
CMS1_k127_2092957_9 Polycystin cation channel K08714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 300.0
CMS1_k127_2135544_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.205e-233 736.0
CMS1_k127_2135544_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.183e-232 727.0
CMS1_k127_2135544_10 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.0000000000000000000000000000000000000000000000000146 184.0
CMS1_k127_2135544_11 COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism K06023 - - 0.00000000000000000000000000000000000001071 149.0
CMS1_k127_2135544_12 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000001141 143.0
CMS1_k127_2135544_13 COG1925 Phosphotransferase system, HPr-related proteins K11189 - - 0.000000000000000004745 89.0
CMS1_k127_2135544_2 PAS PAC domain-containing protein - - - 9.156e-209 676.0
CMS1_k127_2135544_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 532.0
CMS1_k127_2135544_4 COG0642 Signal transduction histidine kinase K14980 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 527.0
CMS1_k127_2135544_5 reductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 457.0
CMS1_k127_2135544_6 transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 375.0
CMS1_k127_2135544_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K14981 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 361.0
CMS1_k127_2135544_8 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 351.0
CMS1_k127_2135544_9 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000001471 190.0
CMS1_k127_2349998_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 568.0
CMS1_k127_2349998_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858,K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 489.0
CMS1_k127_2349998_10 Flavin reductase like domain - - - 0.00000000000000000000000000000000003067 145.0
CMS1_k127_2349998_11 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000007381 120.0
CMS1_k127_2349998_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 378.0
CMS1_k127_2349998_3 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 347.0
CMS1_k127_2349998_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001629 250.0
CMS1_k127_2349998_5 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005157 234.0
CMS1_k127_2349998_6 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000005986 224.0
CMS1_k127_2349998_7 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000008643 214.0
CMS1_k127_2349998_8 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000006437 212.0
CMS1_k127_2349998_9 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000001889 192.0
CMS1_k127_2393568_0 ABC transporter K06020 - 3.6.3.25 4.579e-260 812.0
CMS1_k127_2393568_1 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 384.0
CMS1_k127_2453569_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 3.508e-201 655.0
CMS1_k127_2453569_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 6.749e-195 625.0
CMS1_k127_2453569_2 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007312 473.0
CMS1_k127_2453569_3 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000407 246.0
CMS1_k127_2453569_4 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000003585 228.0
CMS1_k127_2453569_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000002318 181.0
CMS1_k127_2453569_6 Glycosyltransferase family 25 (LPS biosynthesis protein) K07270 - - 0.0000000000000000000000000001001 126.0
CMS1_k127_2453569_7 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K13796 - - 0.0000000000000000000000000004466 121.0
CMS1_k127_2524421_0 COG1960 Acyl-CoA dehydrogenases K14448 - 1.3.8.12 8.949e-216 683.0
CMS1_k127_2524421_1 Circularly permuted ATP-grasp type 2 - - - 6.799e-211 664.0
CMS1_k127_2524421_10 Electron transfer flavoprotein, beta subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 376.0
CMS1_k127_2524421_11 Glutaminase K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 357.0
CMS1_k127_2524421_12 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 350.0
CMS1_k127_2524421_13 cell division K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 323.0
CMS1_k127_2524421_14 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 306.0
CMS1_k127_2524421_15 PFAM 20S proteasome, A and B subunits K07395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001044 280.0
CMS1_k127_2524421_16 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006144 284.0
CMS1_k127_2524421_17 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004616 291.0
CMS1_k127_2524421_18 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000002727 263.0
CMS1_k127_2524421_19 DedA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006067 250.0
CMS1_k127_2524421_2 argininosuccinate lyase K01755 - 4.3.2.1 3.199e-202 642.0
CMS1_k127_2524421_20 Ankyrin repeat K06867,K21440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009558 248.0
CMS1_k127_2524421_21 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000008592 244.0
CMS1_k127_2524421_22 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000001972 245.0
CMS1_k127_2524421_23 Protein of unknown function (DUF1194) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001065 239.0
CMS1_k127_2524421_24 ornithine cyclodeaminase mu-crystallin K19244 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000006505 232.0
CMS1_k127_2524421_25 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000000003853 227.0
CMS1_k127_2524421_26 Cell division protein K09811 - - 0.00000000000000000000000000000000000000000000000000000000000009987 233.0
CMS1_k127_2524421_27 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000003005 220.0
CMS1_k127_2524421_28 iron ion homeostasis K02012 - - 0.0000000000000000000000000000000000000000000000000000001918 215.0
CMS1_k127_2524421_29 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000007281 186.0
CMS1_k127_2524421_3 Domain of unknown function (DUF4175) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 621.0
CMS1_k127_2524421_30 iron ion homeostasis K02012 - - 0.000000000000000000000000000000000000000000000008507 194.0
CMS1_k127_2524421_31 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000007619 180.0
CMS1_k127_2524421_32 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.0000000000000000000000000000000000000000000001414 187.0
CMS1_k127_2524421_33 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000001748 175.0
CMS1_k127_2524421_34 Response regulator receiver - - - 0.0000000000000000000000000000000000000001008 160.0
CMS1_k127_2524421_35 Dopa 4,5-dioxygenase family K10253 - - 0.00000000000000000000000000000000000001378 147.0
CMS1_k127_2524421_36 Cupin domain - - - 0.000000000000000000000000000000000002144 144.0
CMS1_k127_2524421_37 Protein of unknown function (DUF3426) - - - 0.00000000000000000000000000000000017 144.0
CMS1_k127_2524421_38 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.0000000000000000000000000000000009496 134.0
CMS1_k127_2524421_39 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000003506 136.0
CMS1_k127_2524421_4 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008656 534.0
CMS1_k127_2524421_40 bond formation protein, DsbB - - - 0.000000000000000000000000000000006562 141.0
CMS1_k127_2524421_41 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.0000000000000000000001653 102.0
CMS1_k127_2524421_42 Metallopeptidase family M24 - - - 0.0000000000000004552 92.0
CMS1_k127_2524421_43 4Fe-4S single cluster domain - - - 0.0000000000000008426 88.0
CMS1_k127_2524421_44 Domain of unknown function (DUF4259) - - - 0.00000000006939 71.0
CMS1_k127_2524421_45 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000988 61.0
CMS1_k127_2524421_46 small membrane protein - - - 0.0000002848 59.0
CMS1_k127_2524421_47 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.000004096 59.0
CMS1_k127_2524421_48 Glutathione transferase K21253,K21264,K21265 - 2.5.1.18 0.00001316 57.0
CMS1_k127_2524421_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 530.0
CMS1_k127_2524421_6 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 535.0
CMS1_k127_2524421_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 437.0
CMS1_k127_2524421_8 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 425.0
CMS1_k127_2524421_9 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 393.0
CMS1_k127_2550108_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 1.173e-258 811.0
CMS1_k127_2550108_1 RimK-like ATP-grasp domain - - - 3.487e-211 672.0
CMS1_k127_2550108_10 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 298.0
CMS1_k127_2550108_11 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000244 297.0
CMS1_k127_2550108_12 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000049 267.0
CMS1_k127_2550108_13 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000005421 220.0
CMS1_k127_2550108_14 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000009886 217.0
CMS1_k127_2550108_15 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000009887 210.0
CMS1_k127_2550108_16 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000000000000000000000000003288 214.0
CMS1_k127_2550108_17 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000001322 198.0
CMS1_k127_2550108_18 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000001531 179.0
CMS1_k127_2550108_19 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000000000000000000000007032 182.0
CMS1_k127_2550108_2 peptidase M42 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 499.0
CMS1_k127_2550108_20 Protein of unknown function (DUF3833) - - - 0.00000000000000000000000000000000000004067 149.0
CMS1_k127_2550108_21 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000001572 145.0
CMS1_k127_2550108_22 Belongs to the ompA family - - - 0.000000000000000000000000000002013 134.0
CMS1_k127_2550108_23 Cupin domain - - - 0.0000000000000000000000000001319 128.0
CMS1_k127_2550108_24 Metallopeptidase family M24 - - - 0.00000000000000000000002417 114.0
CMS1_k127_2550108_25 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000001719 98.0
CMS1_k127_2550108_26 PFAM Rieske 2Fe-2S domain K02636 - 1.10.9.1 0.00000000000006856 82.0
CMS1_k127_2550108_27 ChrR Cupin-like domain K07167 - - 0.00000000009996 62.0
CMS1_k127_2550108_28 lactoylglutathione lyase activity K11210,K21253,K21264,K21265 GO:0003674,GO:0003824,GO:0004364,GO:0008150,GO:0016740,GO:0016765,GO:0042221,GO:0046677,GO:0050896 2.5.1.18 0.000000002553 64.0
CMS1_k127_2550108_29 Glyoxalase-like domain K01759 - 4.4.1.5 0.00009042 53.0
CMS1_k127_2550108_3 ABC-type Fe3 transport system permease component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 464.0
CMS1_k127_2550108_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 428.0
CMS1_k127_2550108_5 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 400.0
CMS1_k127_2550108_6 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 381.0
CMS1_k127_2550108_7 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 348.0
CMS1_k127_2550108_8 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 342.0
CMS1_k127_2550108_9 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 328.0
CMS1_k127_2746039_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 2.76e-248 785.0
CMS1_k127_2746039_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.63e-205 647.0
CMS1_k127_2746039_10 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 327.0
CMS1_k127_2746039_11 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 330.0
CMS1_k127_2746039_12 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 293.0
CMS1_k127_2746039_13 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003453 282.0
CMS1_k127_2746039_14 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005833 277.0
CMS1_k127_2746039_15 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002143 273.0
CMS1_k127_2746039_16 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000009532 233.0
CMS1_k127_2746039_17 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000002589 231.0
CMS1_k127_2746039_18 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000003702 206.0
CMS1_k127_2746039_19 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000000000006291 191.0
CMS1_k127_2746039_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.539e-200 635.0
CMS1_k127_2746039_20 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000001551 168.0
CMS1_k127_2746039_21 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000006221 160.0
CMS1_k127_2746039_22 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000001015 154.0
CMS1_k127_2746039_23 EamA-like transporter family - - - 0.000000000000000000000000000000003239 131.0
CMS1_k127_2746039_24 Smr domain - - - 0.00000000000000000000000000000001003 134.0
CMS1_k127_2746039_25 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.0000000000000000000000000000000707 131.0
CMS1_k127_2746039_26 COG3030 Protein affecting phage T7 exclusion by the F plasmid K07113 - - 0.000000000000000000000000000004895 132.0
CMS1_k127_2746039_27 Protein of unknown function (DUF2628) - - - 0.0000000000000002814 84.0
CMS1_k127_2746039_3 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 449.0
CMS1_k127_2746039_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 438.0
CMS1_k127_2746039_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 417.0
CMS1_k127_2746039_6 membrane-bound lytic murein transglycosylase K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 411.0
CMS1_k127_2746039_7 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 366.0
CMS1_k127_2746039_8 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 348.0
CMS1_k127_2746039_9 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 357.0
CMS1_k127_2758881_0 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0 1651.0
CMS1_k127_2758881_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 5.981e-314 972.0
CMS1_k127_2758881_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 445.0
CMS1_k127_2758881_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 381.0
CMS1_k127_2758881_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 304.0
CMS1_k127_2758881_5 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008023 255.0
CMS1_k127_2758881_6 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000001662 243.0
CMS1_k127_2758881_7 COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.00000000000000000000007132 106.0
CMS1_k127_2758881_8 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 0.00000000000001654 72.0
CMS1_k127_2854539_0 maleylacetate reductase K00217 - 1.3.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 369.0
CMS1_k127_2854539_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000009814 141.0
CMS1_k127_2854539_2 - - - - 0.0000000000000000000000000000000001723 141.0
CMS1_k127_2854539_3 Resolvase - - - 0.0000006857 53.0
CMS1_k127_2902149_0 Formate dehydrogenase subunit alpha K00123 - 1.17.1.9 0.0 1534.0
CMS1_k127_2902149_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 3.369e-294 908.0
CMS1_k127_2902149_10 2Fe-2S iron-sulfur cluster binding domain K00491,K21324 - 1.14.14.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002453 287.0
CMS1_k127_2902149_11 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007199 271.0
CMS1_k127_2902149_12 transcriptional regulator K19338 - - 0.00000000000000000000000000000000000000000000000000000000002001 221.0
CMS1_k127_2902149_13 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00127 - - 0.0000000000000000000000000000000000000000000000000005836 189.0
CMS1_k127_2902149_14 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000005971 135.0
CMS1_k127_2902149_15 NADH-dependant formate dehydrogenase delta subunit FdsD - - - 0.0000000000000005669 83.0
CMS1_k127_2902149_2 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00124,K18005 - 1.12.1.2 1.473e-234 735.0
CMS1_k127_2902149_3 Aldehyde dehydrogenase family K15514 - 1.2.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 589.0
CMS1_k127_2902149_4 CoA-transferase family III K07544 - 2.8.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 515.0
CMS1_k127_2902149_5 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 506.0
CMS1_k127_2902149_6 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 436.0
CMS1_k127_2902149_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 376.0
CMS1_k127_2902149_8 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 315.0
CMS1_k127_2902149_9 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 304.0
CMS1_k127_3118711_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1024.0
CMS1_k127_3118711_1 DNA Topoisomerase IV K02621 - - 0.0 1012.0
CMS1_k127_3118711_10 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000318 252.0
CMS1_k127_3118711_11 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000006545 247.0
CMS1_k127_3118711_12 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000000000008604 203.0
CMS1_k127_3118711_13 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000008245 187.0
CMS1_k127_3118711_14 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000002675 190.0
CMS1_k127_3118711_15 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000005627 179.0
CMS1_k127_3118711_16 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000002381 138.0
CMS1_k127_3118711_2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 490.0
CMS1_k127_3118711_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 439.0
CMS1_k127_3118711_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 366.0
CMS1_k127_3118711_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 355.0
CMS1_k127_3118711_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 358.0
CMS1_k127_3118711_7 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 291.0
CMS1_k127_3118711_8 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 291.0
CMS1_k127_3118711_9 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000679 265.0
CMS1_k127_3258425_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0 1426.0
CMS1_k127_3258425_1 DNA helicase K03657 - 3.6.4.12 2.018e-309 966.0
CMS1_k127_3258425_10 Tripartite ATP-independent periplasmic transporter, DctM component - - - 8.323e-203 640.0
CMS1_k127_3258425_11 Rod shape-determining protein MreB K03569 - - 1.084e-202 633.0
CMS1_k127_3258425_12 Chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 589.0
CMS1_k127_3258425_13 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 569.0
CMS1_k127_3258425_14 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 562.0
CMS1_k127_3258425_15 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008756 568.0
CMS1_k127_3258425_16 COG4663 TRAP-type mannitol chloroaromatic compound transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 559.0
CMS1_k127_3258425_17 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 554.0
CMS1_k127_3258425_18 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 542.0
CMS1_k127_3258425_19 AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 562.0
CMS1_k127_3258425_2 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 2.426e-289 900.0
CMS1_k127_3258425_20 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 535.0
CMS1_k127_3258425_21 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008803 516.0
CMS1_k127_3258425_22 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 515.0
CMS1_k127_3258425_23 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 509.0
CMS1_k127_3258425_24 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 516.0
CMS1_k127_3258425_25 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 491.0
CMS1_k127_3258425_26 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 457.0
CMS1_k127_3258425_27 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 461.0
CMS1_k127_3258425_28 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 438.0
CMS1_k127_3258425_29 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 438.0
CMS1_k127_3258425_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 7.428e-272 863.0
CMS1_k127_3258425_30 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 385.0
CMS1_k127_3258425_31 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 381.0
CMS1_k127_3258425_32 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009791 362.0
CMS1_k127_3258425_33 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 352.0
CMS1_k127_3258425_34 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 366.0
CMS1_k127_3258425_35 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 346.0
CMS1_k127_3258425_36 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 336.0
CMS1_k127_3258425_37 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 323.0
CMS1_k127_3258425_38 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 313.0
CMS1_k127_3258425_39 mandelate racemase muconate lactonizing K01856 - 5.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 321.0
CMS1_k127_3258425_4 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.03e-263 823.0
CMS1_k127_3258425_40 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 312.0
CMS1_k127_3258425_41 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006885 284.0
CMS1_k127_3258425_42 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001421 272.0
CMS1_k127_3258425_43 Acetolactate synthase small K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000006734 259.0
CMS1_k127_3258425_44 COG3023 Negative regulator of beta-lactamase expression K01447 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000002235 252.0
CMS1_k127_3258425_45 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000367 224.0
CMS1_k127_3258425_46 Cell division protein FtsQ K03589 - - 0.0000000000000000000000000000000000000000000000000000000000209 218.0
CMS1_k127_3258425_47 TIM-barrel fold metal-dependent hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000007104 215.0
CMS1_k127_3258425_48 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000634 212.0
CMS1_k127_3258425_49 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000001101 213.0
CMS1_k127_3258425_5 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 6.97e-255 795.0
CMS1_k127_3258425_50 Alpha/beta hydrolase family K07020 - - 0.000000000000000000000000000000000000000000000000000004799 200.0
CMS1_k127_3258425_51 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000001484 193.0
CMS1_k127_3258425_52 ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000004114 207.0
CMS1_k127_3258425_53 shape-determining protein K03571 - - 0.000000000000000000000000000000000000004374 158.0
CMS1_k127_3258425_54 Stringent starvation protein B K09985 - - 0.0000000000000000000000000000000000004438 146.0
CMS1_k127_3258425_55 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000003097 120.0
CMS1_k127_3258425_56 TfoX N-terminal domain K07343 - - 0.000000000000000000000107 104.0
CMS1_k127_3258425_57 - - - - 0.000000000000000000001808 98.0
CMS1_k127_3258425_58 Protein of unknown function (DUF1622) - - - 0.000000000000000001256 92.0
CMS1_k127_3258425_59 - - - - 0.000000000000000001979 91.0
CMS1_k127_3258425_6 Cell division protein FtsI penicillin-binding protein 2 K05515 - 3.4.16.4 1.723e-246 777.0
CMS1_k127_3258425_60 Response regulator receiver K11443 - - 0.0000000000000001092 87.0
CMS1_k127_3258425_61 protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis - - - 0.000000000000000462 79.0
CMS1_k127_3258425_7 aminopeptidase K01262 - 3.4.11.9 1.109e-230 733.0
CMS1_k127_3258425_8 Belongs to the MurCDEF family K01924 - 6.3.2.8 3.361e-223 702.0
CMS1_k127_3258425_9 COG0768 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 6.876e-214 693.0
CMS1_k127_348689_0 Flavin containing amine oxidoreductase K09845 - 1.3.99.27 1.849e-240 753.0
CMS1_k127_348689_1 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 511.0
CMS1_k127_348689_10 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000001147 202.0
CMS1_k127_348689_11 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000001194 204.0
CMS1_k127_348689_12 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000002649 184.0
CMS1_k127_348689_13 - - - - 0.00000000000000000000000000000000000000000000000005006 186.0
CMS1_k127_348689_14 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000009868 189.0
CMS1_k127_348689_15 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000002153 183.0
CMS1_k127_348689_16 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000006771 176.0
CMS1_k127_348689_17 acetyltransferase - - - 0.000000000000000000000000000000000000000000000209 177.0
CMS1_k127_348689_18 surface antigen - - - 0.00000000000000000000000000000000000000000009282 167.0
CMS1_k127_348689_19 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000001808 158.0
CMS1_k127_348689_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 434.0
CMS1_k127_348689_20 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000000000000000000000000004052 115.0
CMS1_k127_348689_21 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000003649 96.0
CMS1_k127_348689_22 Protein of unknown function (DUF3568) - - - 0.000000000000000001629 91.0
CMS1_k127_348689_23 - - - - 0.00000000000000004032 89.0
CMS1_k127_348689_24 PFAM Protein kinase domain - - - 0.000000002162 70.0
CMS1_k127_348689_25 - - - - 0.0000007005 54.0
CMS1_k127_348689_26 17 kDa outer membrane surface antigen - - - 0.000002387 60.0
CMS1_k127_348689_3 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 324.0
CMS1_k127_348689_4 Pyruvate 2-oxoglutarate dehydrogenase complex dehydrogenase (E1) component eukaryotic type beta subunit K00162,K11381 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 304.0
CMS1_k127_348689_5 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006163 273.0
CMS1_k127_348689_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001882 273.0
CMS1_k127_348689_7 PFAM dehydrogenase, E1 component K21416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000153 266.0
CMS1_k127_348689_8 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000002727 226.0
CMS1_k127_348689_9 17 kDa outer membrane surface antigen - - - 0.00000000000000000000000000000000000000000000000000000001231 203.0
CMS1_k127_3519443_0 Ornithine cyclodeaminase/mu-crystallin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 353.0
CMS1_k127_3519443_1 Ornithine cyclodeaminase/mu-crystallin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 328.0
CMS1_k127_3519443_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000006507 94.0
CMS1_k127_3713613_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.55e-237 739.0
CMS1_k127_3713613_1 Involved in the TonB-independent uptake of proteins K03641 - - 7.533e-211 664.0
CMS1_k127_3713613_10 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001587 286.0
CMS1_k127_3713613_11 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000526 246.0
CMS1_k127_3713613_12 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000001415 209.0
CMS1_k127_3713613_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000001764 212.0
CMS1_k127_3713613_14 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000000003935 198.0
CMS1_k127_3713613_15 Biopolymer transport protein K03559,K03560 - - 0.000000000000000000000000000000000000000000000000004008 185.0
CMS1_k127_3713613_16 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000001579 180.0
CMS1_k127_3713613_17 TIGRFAM protein TolA - - - 0.00000000000000000000000000000000000000003115 166.0
CMS1_k127_3713613_18 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000006888 138.0
CMS1_k127_3713613_19 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000008034 104.0
CMS1_k127_3713613_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 496.0
CMS1_k127_3713613_20 - - - - 0.0000000000002596 78.0
CMS1_k127_3713613_3 Lipoprotein releasing system transmembrane protein LolC K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0098796,GO:0098797 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 485.0
CMS1_k127_3713613_4 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 424.0
CMS1_k127_3713613_5 Protein conserved in bacteria K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 366.0
CMS1_k127_3713613_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 336.0
CMS1_k127_3713613_7 COG0811 Biopolymer transport proteins K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 320.0
CMS1_k127_3713613_8 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 316.0
CMS1_k127_3713613_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 304.0
CMS1_k127_3716330_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1307.0
CMS1_k127_3716330_1 COG1138 Cytochrome c biogenesis factor K02198 - - 6.586e-286 902.0
CMS1_k127_3716330_10 Putative beta-barrel porin 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 340.0
CMS1_k127_3716330_11 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 320.0
CMS1_k127_3716330_12 Mitochondrial fission ELM1 K07276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001268 289.0
CMS1_k127_3716330_13 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K15060 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007438 275.0
CMS1_k127_3716330_14 Staphylococcal nuclease homologue - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002128 255.0
CMS1_k127_3716330_15 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002023 246.0
CMS1_k127_3716330_16 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000003452 239.0
CMS1_k127_3716330_17 transcriptional regulator K07736 - - 0.000000000000000000000000000000000000000000000000000000000000008787 230.0
CMS1_k127_3716330_18 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000004961 218.0
CMS1_k127_3716330_19 - K13662 - - 0.0000000000000000000000000000000000000000000000000000000000006641 227.0
CMS1_k127_3716330_2 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 1.051e-277 858.0
CMS1_k127_3716330_20 Glycosyl transferase WecB/TagA/CpsF family K05946,K13660 - 2.4.1.187 0.0000000000000000000000000000000000000000000000000000000000007137 219.0
CMS1_k127_3716330_21 Protein of unknown function (DUF938) - - - 0.00000000000000000000000000000000000000000000000000000000001921 214.0
CMS1_k127_3716330_22 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000003529 224.0
CMS1_k127_3716330_23 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000002725 203.0
CMS1_k127_3716330_24 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000000000000000002864 211.0
CMS1_k127_3716330_25 periplasmic protein thiol disulfide K02199 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000001722 205.0
CMS1_k127_3716330_26 Glycosyltransferase K13657 - 2.4.1.252 0.000000000000000000000000000000000000000000000000000137 200.0
CMS1_k127_3716330_27 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000004388 190.0
CMS1_k127_3716330_28 polysaccharide export K01991 - - 0.000000000000000000000000000000000000000000000002185 179.0
CMS1_k127_3716330_29 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000003719 181.0
CMS1_k127_3716330_3 COG0513 Superfamily II DNA and RNA helicases K17675 - 3.6.4.13 2.331e-254 818.0
CMS1_k127_3716330_31 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000000000000005533 175.0
CMS1_k127_3716330_32 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000000002385 166.0
CMS1_k127_3716330_33 COG4235 Cytochrome c biogenesis factor K02200 - - 0.000000000000000000000000000000000000000012 164.0
CMS1_k127_3716330_34 Putative molybdenum carrier - - - 0.00000000000000000000000000000000000000522 151.0
CMS1_k127_3716330_35 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.000000000000000000000000000000000001292 143.0
CMS1_k127_3716330_36 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000000000000000000000000001131 139.0
CMS1_k127_3716330_37 Cupin domain - - - 0.000000000000000000000000000000006481 128.0
CMS1_k127_3716330_38 Cupin domain - - - 0.000000000000000000000000000003395 121.0
CMS1_k127_3716330_39 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000003351 116.0
CMS1_k127_3716330_4 - - - - 1.38e-233 740.0
CMS1_k127_3716330_40 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.0000000000000000000003065 107.0
CMS1_k127_3716330_41 Belongs to the universal stress protein A family - - - 0.0000000000000000000004285 109.0
CMS1_k127_3716330_42 - - - - 0.00000000006865 72.0
CMS1_k127_3716330_44 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00073 44.0
CMS1_k127_3716330_5 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 507.0
CMS1_k127_3716330_6 Chain length determinant protein K16554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 460.0
CMS1_k127_3716330_7 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 423.0
CMS1_k127_3716330_8 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 355.0
CMS1_k127_3716330_9 sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 356.0
CMS1_k127_3757777_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 3.247e-233 745.0
CMS1_k127_3757777_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 536.0
CMS1_k127_3757777_10 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000000000006803 102.0
CMS1_k127_3757777_11 COG0346 Lactoylglutathione lyase and related lyases K08234 - - 0.000000152 61.0
CMS1_k127_3757777_12 Cupin domain - - - 0.000003446 58.0
CMS1_k127_3757777_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 409.0
CMS1_k127_3757777_3 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 394.0
CMS1_k127_3757777_4 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 321.0
CMS1_k127_3757777_5 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 313.0
CMS1_k127_3757777_6 ABC-type Fe3 transport system permease component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001228 250.0
CMS1_k127_3757777_7 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000001832 237.0
CMS1_k127_3757777_8 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000000309 203.0
CMS1_k127_3757777_9 Protein of unknown function (DUF1491) - - - 0.000000000000000000000000008302 113.0
CMS1_k127_377083_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.785e-278 877.0
CMS1_k127_377083_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.597e-224 717.0
CMS1_k127_377083_10 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000003686 234.0
CMS1_k127_377083_11 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000001403 227.0
CMS1_k127_377083_12 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000003632 211.0
CMS1_k127_377083_13 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000002128 198.0
CMS1_k127_377083_14 Probable molybdopterin binding domain K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000004357 190.0
CMS1_k127_377083_15 XdhC and CoxI family - - - 0.00000000000000000000000000000000003879 137.0
CMS1_k127_377083_16 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000001067 136.0
CMS1_k127_377083_17 Catalyzes the conversion of maleate to fumarate K01799,K06033 - 4.1.1.76,5.2.1.1 0.000000000000000000000000004595 127.0
CMS1_k127_377083_18 Catalyzes the conversion of maleate to fumarate K01799,K06033 - 4.1.1.76,5.2.1.1 0.00000000000000000000000001927 118.0
CMS1_k127_377083_19 PFAM alpha beta hydrolase fold K02170 - 3.1.1.85 0.0000000000000000000000001277 122.0
CMS1_k127_377083_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 4.22e-197 632.0
CMS1_k127_377083_20 ornithine cyclodeaminase K01750 - 4.3.1.12 0.000000000000000000007926 105.0
CMS1_k127_377083_23 Catalyzes the conversion of maleate to fumarate K01799 - 5.2.1.1 0.00000000000000817 86.0
CMS1_k127_377083_24 - - - - 0.0000000000009891 71.0
CMS1_k127_377083_25 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.0000000001961 72.0
CMS1_k127_377083_3 Transmembrane secretion effector K08217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 338.0
CMS1_k127_377083_4 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 327.0
CMS1_k127_377083_5 MmgE PrpD family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003555 253.0
CMS1_k127_377083_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000001603 253.0
CMS1_k127_377083_7 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000007466 244.0
CMS1_k127_377083_8 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004669 231.0
CMS1_k127_377083_9 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000006379 229.0
CMS1_k127_3795659_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 2.359e-206 652.0
CMS1_k127_3795659_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 621.0
CMS1_k127_3795659_2 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 521.0
CMS1_k127_3795659_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 469.0
CMS1_k127_3795659_4 HNH endonuclease K07454 - - 0.000000000000000000000000000000000000000000000000000000007687 207.0
CMS1_k127_3795659_5 Phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.000000000000000000000000000000000005652 144.0
CMS1_k127_3795659_6 Domain of unknown function (DUF4297) - - - 0.000000000000000000000000008488 123.0
CMS1_k127_3795659_7 - - - - 0.00000000000000000002021 93.0
CMS1_k127_3795659_9 Trypsin-like serine protease - - - 0.00000000002275 75.0
CMS1_k127_3801758_0 DNA polymerase K02337 - 2.7.7.7 0.0 1433.0
CMS1_k127_3801758_1 haloacid dehalogenase-like hydrolase - - - 1.034e-307 961.0
CMS1_k127_3801758_10 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 6.391e-223 702.0
CMS1_k127_3801758_11 COG0477 Permeases of the major facilitator superfamily - - - 2.982e-215 681.0
CMS1_k127_3801758_12 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 8.416e-215 680.0
CMS1_k127_3801758_13 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.166e-207 650.0
CMS1_k127_3801758_14 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.562e-205 647.0
CMS1_k127_3801758_15 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.675e-203 642.0
CMS1_k127_3801758_16 Potassium transporter peripheral membrane component K03499 - - 1.572e-202 639.0
CMS1_k127_3801758_17 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 609.0
CMS1_k127_3801758_18 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 591.0
CMS1_k127_3801758_19 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 559.0
CMS1_k127_3801758_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.548e-285 882.0
CMS1_k127_3801758_20 PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 514.0
CMS1_k127_3801758_21 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 483.0
CMS1_k127_3801758_22 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003052 478.0
CMS1_k127_3801758_23 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 460.0
CMS1_k127_3801758_24 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 462.0
CMS1_k127_3801758_25 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 452.0
CMS1_k127_3801758_26 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 449.0
CMS1_k127_3801758_27 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 444.0
CMS1_k127_3801758_28 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 447.0
CMS1_k127_3801758_29 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 437.0
CMS1_k127_3801758_3 Multicopper oxidase - - - 4.274e-235 745.0
CMS1_k127_3801758_30 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 409.0
CMS1_k127_3801758_31 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 408.0
CMS1_k127_3801758_32 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 396.0
CMS1_k127_3801758_33 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 407.0
CMS1_k127_3801758_34 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 381.0
CMS1_k127_3801758_35 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 377.0
CMS1_k127_3801758_36 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 377.0
CMS1_k127_3801758_37 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 370.0
CMS1_k127_3801758_38 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 351.0
CMS1_k127_3801758_39 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 358.0
CMS1_k127_3801758_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 3.18e-234 754.0
CMS1_k127_3801758_40 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 336.0
CMS1_k127_3801758_41 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 330.0
CMS1_k127_3801758_42 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007337 329.0
CMS1_k127_3801758_43 Amino-transferase class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 331.0
CMS1_k127_3801758_44 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 320.0
CMS1_k127_3801758_45 COG0512 Anthranilate para-aminobenzoate synthases component II K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008326 296.0
CMS1_k127_3801758_46 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 296.0
CMS1_k127_3801758_47 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 295.0
CMS1_k127_3801758_48 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001338 285.0
CMS1_k127_3801758_49 protein conserved in bacteria K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002769 285.0
CMS1_k127_3801758_5 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 7.801e-234 732.0
CMS1_k127_3801758_50 Copper resistance protein B precursor (CopB) K07233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000347 289.0
CMS1_k127_3801758_51 protein conserved in bacteria K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000033 273.0
CMS1_k127_3801758_52 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000005457 241.0
CMS1_k127_3801758_53 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001559 244.0
CMS1_k127_3801758_54 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000002631 235.0
CMS1_k127_3801758_55 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000001492 226.0
CMS1_k127_3801758_56 hyperosmotic response K03286,K04065 - - 0.00000000000000000000000000000000000000000000000000000000000004774 223.0
CMS1_k127_3801758_57 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000004547 215.0
CMS1_k127_3801758_58 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000009314 226.0
CMS1_k127_3801758_59 iron ion homeostasis K02012 - - 0.0000000000000000000000000000000000000000000000000000000002514 223.0
CMS1_k127_3801758_6 COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 - 2.7.13.3 5.791e-228 730.0
CMS1_k127_3801758_60 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000000000000000000000000000000000005283 202.0
CMS1_k127_3801758_61 COG0224 F0F1-type ATP synthase, gamma subunit K02115 - - 0.0000000000000000000000000000000000000000000000000000003037 205.0
CMS1_k127_3801758_62 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000000000000003502 199.0
CMS1_k127_3801758_63 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000007499 203.0
CMS1_k127_3801758_64 PFAM isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000002853 188.0
CMS1_k127_3801758_65 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15270 - - 0.0000000000000000000000000000000000000000000000002685 189.0
CMS1_k127_3801758_66 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000007115 175.0
CMS1_k127_3801758_67 COG2867 Oligoketide cyclase lipid transport protein K18588 - - 0.000000000000000000000000000000000000000000001715 169.0
CMS1_k127_3801758_68 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000005856 175.0
CMS1_k127_3801758_69 - - - - 0.00000000000000000000000000000000000000001015 162.0
CMS1_k127_3801758_7 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 2.489e-226 709.0
CMS1_k127_3801758_70 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000127 159.0
CMS1_k127_3801758_71 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000002643 154.0
CMS1_k127_3801758_72 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000002228 152.0
CMS1_k127_3801758_73 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000004903 154.0
CMS1_k127_3801758_74 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000008199 141.0
CMS1_k127_3801758_75 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000002663 146.0
CMS1_k127_3801758_76 proton-transporting ATP synthase activity, rotational mechanism K02114 - - 0.000000000000000000000000000000000008335 141.0
CMS1_k127_3801758_77 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.0000000000000000000000000001258 117.0
CMS1_k127_3801758_78 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.00000000000000000000000003384 111.0
CMS1_k127_3801758_79 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000003599 119.0
CMS1_k127_3801758_8 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.878e-224 703.0
CMS1_k127_3801758_80 - - - - 0.00000000000000000000000005035 108.0
CMS1_k127_3801758_81 Preprotein translocase subunit SecG K03075 - - 0.000000000000000000000002892 107.0
CMS1_k127_3801758_82 Septum formation initiator - - - 0.0000000000000000000001209 102.0
CMS1_k127_3801758_83 Outer membrane protein (OmpH-like) - - - 0.000000000000001471 84.0
CMS1_k127_3801758_84 - - - - 0.000000000000001787 83.0
CMS1_k127_3801758_85 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000002328 81.0
CMS1_k127_3801758_86 Cupin domain - - - 0.0000000411 63.0
CMS1_k127_3801758_87 CAAX protease self-immunity K07052,K09696 - - 0.0000254 55.0
CMS1_k127_3801758_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.28e-224 705.0
CMS1_k127_3822448_0 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 6.365e-277 874.0
CMS1_k127_3822448_1 Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 590.0
CMS1_k127_3822448_10 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002508 255.0
CMS1_k127_3822448_11 to the N-terminal domain of Lon protease K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000001519 232.0
CMS1_k127_3822448_12 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000001486 197.0
CMS1_k127_3822448_13 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000001115 192.0
CMS1_k127_3822448_14 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000001117 185.0
CMS1_k127_3822448_15 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751,K04752 - - 0.0000000000000000000000000000000000000000000001014 172.0
CMS1_k127_3822448_16 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000005656 173.0
CMS1_k127_3822448_17 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000009474 177.0
CMS1_k127_3822448_18 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000574 165.0
CMS1_k127_3822448_19 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000676 134.0
CMS1_k127_3822448_2 PFAM Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 498.0
CMS1_k127_3822448_20 Belongs to the UPF0434 family K09791 - - 0.00000000000000000000007051 99.0
CMS1_k127_3822448_21 - - - - 0.0000000000000000004199 95.0
CMS1_k127_3822448_22 Prolyl 4-hydroxylase alpha subunit homologues. K07336 - - 0.000000000000001471 84.0
CMS1_k127_3822448_23 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000006823 80.0
CMS1_k127_3822448_24 Cupin 4 family protein - - - 0.000000000002222 78.0
CMS1_k127_3822448_26 Gram-negative porin - - - 0.0003509 52.0
CMS1_k127_3822448_3 COG0436 Aspartate tyrosine aromatic aminotransferase K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 418.0
CMS1_k127_3822448_4 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 399.0
CMS1_k127_3822448_5 COG0708 Exonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004658 376.0
CMS1_k127_3822448_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 338.0
CMS1_k127_3822448_7 FAD binding domain K03185 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016491,GO:0019168,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 344.0
CMS1_k127_3822448_8 Thioredoxin K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 326.0
CMS1_k127_3822448_9 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 293.0
CMS1_k127_3871216_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.067e-282 874.0
CMS1_k127_3871216_1 peptidase U62, modulator of DNA gyrase K03568 - - 8.709e-220 694.0
CMS1_k127_3871216_10 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 392.0
CMS1_k127_3871216_11 Glycine cleavage system T protein K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 344.0
CMS1_k127_3871216_12 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 332.0
CMS1_k127_3871216_13 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 326.0
CMS1_k127_3871216_14 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005527 260.0
CMS1_k127_3871216_15 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000181 269.0
CMS1_k127_3871216_16 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000009934 250.0
CMS1_k127_3871216_17 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008238 258.0
CMS1_k127_3871216_18 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000006278 246.0
CMS1_k127_3871216_19 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000009482 229.0
CMS1_k127_3871216_2 glutamate--cysteine ligase K01919 - 6.3.2.2 7.83e-218 687.0
CMS1_k127_3871216_20 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.0000000000000000000000000000000000000000000000000000001028 203.0
CMS1_k127_3871216_21 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000000000003652 173.0
CMS1_k127_3871216_22 Aspartyl protease K06985 - - 0.00000000000000000000000000000000001633 144.0
CMS1_k127_3871216_23 - - - - 0.00000000000000000000000000000000114 138.0
CMS1_k127_3871216_24 Protein of unknown function (DUF983) - - - 0.00000000000000000000000000000104 124.0
CMS1_k127_3871216_3 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 3.435e-195 620.0
CMS1_k127_3871216_4 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 572.0
CMS1_k127_3871216_5 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 549.0
CMS1_k127_3871216_6 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 512.0
CMS1_k127_3871216_7 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 458.0
CMS1_k127_3871216_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 404.0
CMS1_k127_3871216_9 cytochrome c oxidase K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 397.0
CMS1_k127_4021243_0 GTP-binding protein TypA K06207 - - 1.927e-279 872.0
CMS1_k127_4021243_1 Uncharacterized protein family (UPF0051) K09014 - - 1.618e-254 797.0
CMS1_k127_4021243_10 NADPH:quinone reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 317.0
CMS1_k127_4021243_11 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000629 276.0
CMS1_k127_4021243_12 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000492 263.0
CMS1_k127_4021243_13 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003356 255.0
CMS1_k127_4021243_14 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002637 256.0
CMS1_k127_4021243_15 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000000000000000000000000000000000000000000000000000000000003784 228.0
CMS1_k127_4021243_16 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000103 220.0
CMS1_k127_4021243_17 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000003003 219.0
CMS1_k127_4021243_18 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000000001598 200.0
CMS1_k127_4021243_19 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000008452 198.0
CMS1_k127_4021243_2 Belongs to the DEAD box helicase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 549.0
CMS1_k127_4021243_20 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000001173 188.0
CMS1_k127_4021243_21 Domain of unknown function (DUF4336) - - - 0.0000000000000000000000000000000000000000003651 166.0
CMS1_k127_4021243_22 FeS assembly SUF system protein - - - 0.0000000000000000000000000000000000000000446 154.0
CMS1_k127_4021243_23 Transcriptional regulator - - - 0.00000000000000000000000000000000000001218 149.0
CMS1_k127_4021243_24 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000009536 133.0
CMS1_k127_4021243_25 NfeD-like C-terminal, partner-binding K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000003221 122.0
CMS1_k127_4021243_26 - - - - 0.00000000000000001568 91.0
CMS1_k127_4021243_27 YCII-related domain K09780 - - 0.0000000001797 67.0
CMS1_k127_4021243_28 Flp pilus assembly protein, pilin Flp K02651 - - 0.0000003706 56.0
CMS1_k127_4021243_29 - - - - 0.000005968 55.0
CMS1_k127_4021243_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 509.0
CMS1_k127_4021243_4 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 494.0
CMS1_k127_4021243_5 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 464.0
CMS1_k127_4021243_6 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 415.0
CMS1_k127_4021243_7 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 409.0
CMS1_k127_4021243_8 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 408.0
CMS1_k127_4021243_9 COG0396 ABC-type transport system involved in Fe-S cluster assembly, ATPase component K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 361.0
CMS1_k127_4058226_0 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 394.0
CMS1_k127_4058226_1 Rieske [2Fe-2S] domain K15060 - - 0.000000000000000005855 85.0
CMS1_k127_4103877_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1357.0
CMS1_k127_4103877_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.315e-317 981.0
CMS1_k127_4103877_10 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 562.0
CMS1_k127_4103877_100 - - - - 0.00000001074 62.0
CMS1_k127_4103877_101 PRC-barrel domain - - - 0.0000000987 60.0
CMS1_k127_4103877_102 lactoylglutathione lyase activity K08234 - - 0.000002347 61.0
CMS1_k127_4103877_104 - - - - 0.000007789 49.0
CMS1_k127_4103877_105 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.00001617 55.0
CMS1_k127_4103877_106 PFAM VanZ - - - 0.0001077 50.0
CMS1_k127_4103877_107 Peptidoglycan-binding domain 1 protein K07126,K13582 - - 0.000576 53.0
CMS1_k127_4103877_11 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 567.0
CMS1_k127_4103877_12 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 548.0
CMS1_k127_4103877_13 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 542.0
CMS1_k127_4103877_14 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 508.0
CMS1_k127_4103877_15 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 495.0
CMS1_k127_4103877_16 transport system periplasmic component K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 464.0
CMS1_k127_4103877_17 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 465.0
CMS1_k127_4103877_18 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 460.0
CMS1_k127_4103877_19 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 447.0
CMS1_k127_4103877_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 7.432e-307 963.0
CMS1_k127_4103877_20 Histidine kinase-like ATPases K14980 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 454.0
CMS1_k127_4103877_21 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 441.0
CMS1_k127_4103877_22 COG0437 Fe-S-cluster-containing hydrogenase components 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 409.0
CMS1_k127_4103877_23 Chain length determinant protein K16554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 397.0
CMS1_k127_4103877_24 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 364.0
CMS1_k127_4103877_25 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 357.0
CMS1_k127_4103877_26 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 347.0
CMS1_k127_4103877_27 AMP-binding enzyme C-terminal domain K18661 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 358.0
CMS1_k127_4103877_28 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 349.0
CMS1_k127_4103877_29 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 338.0
CMS1_k127_4103877_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.25e-261 824.0
CMS1_k127_4103877_30 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 354.0
CMS1_k127_4103877_31 Glycosyl transferase 4-like domain K03208 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 348.0
CMS1_k127_4103877_32 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009419 346.0
CMS1_k127_4103877_33 Dihydrodipicolinate synthetase family K14585 - 4.1.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 337.0
CMS1_k127_4103877_34 Transmembrane secretion effector K08217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 334.0
CMS1_k127_4103877_35 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 317.0
CMS1_k127_4103877_36 (LPS) heptosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 323.0
CMS1_k127_4103877_37 Transcriptional regulatory protein, C terminal K14981 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 297.0
CMS1_k127_4103877_38 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 301.0
CMS1_k127_4103877_39 Zinc-binding dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 306.0
CMS1_k127_4103877_4 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 5.501e-243 765.0
CMS1_k127_4103877_40 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 291.0
CMS1_k127_4103877_41 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 286.0
CMS1_k127_4103877_42 Luciferase-like monooxygenase K15854 - 1.14.14.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 292.0
CMS1_k127_4103877_43 Bacterial extracellular solute-binding proteins, family 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002978 286.0
CMS1_k127_4103877_44 DMSO reductase anchor subunit K21309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001953 283.0
CMS1_k127_4103877_45 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002051 272.0
CMS1_k127_4103877_46 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004085 274.0
CMS1_k127_4103877_47 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001669 259.0
CMS1_k127_4103877_48 COG0859 ADP-heptose LPS heptosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001696 267.0
CMS1_k127_4103877_49 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000951 279.0
CMS1_k127_4103877_5 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916 - 6.3.1.5 6.764e-231 726.0
CMS1_k127_4103877_50 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004848 269.0
CMS1_k127_4103877_51 Nad-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004278 256.0
CMS1_k127_4103877_52 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006828 251.0
CMS1_k127_4103877_53 Ribonuclease G K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000001424 254.0
CMS1_k127_4103877_54 Methyltransferase small domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003513 248.0
CMS1_k127_4103877_55 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000007768 241.0
CMS1_k127_4103877_56 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000001072 235.0
CMS1_k127_4103877_57 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000004811 241.0
CMS1_k127_4103877_58 Phytoene synthase K21678 - 2.5.1.103 0.000000000000000000000000000000000000000000000000000000000000000008344 237.0
CMS1_k127_4103877_59 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000009781 225.0
CMS1_k127_4103877_6 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 3.354e-230 721.0
CMS1_k127_4103877_60 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000003119 229.0
CMS1_k127_4103877_61 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000006743 231.0
CMS1_k127_4103877_62 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001624 218.0
CMS1_k127_4103877_63 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000172 236.0
CMS1_k127_4103877_64 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000001129 213.0
CMS1_k127_4103877_65 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000000000000001727 198.0
CMS1_k127_4103877_66 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K08319 - 1.1.1.411 0.000000000000000000000000000000000000000000000000000000205 207.0
CMS1_k127_4103877_67 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000001784 202.0
CMS1_k127_4103877_68 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000131 188.0
CMS1_k127_4103877_69 PFAM Formylglycine-generating sulfatase enzyme K18912,K20333 - 1.14.99.50 0.000000000000000000000000000000000000000000000002337 192.0
CMS1_k127_4103877_7 Phosphate acyltransferases - - - 2.421e-229 739.0
CMS1_k127_4103877_70 PFAM polysaccharide export protein K01991 - - 0.00000000000000000000000000000000000000000000000466 183.0
CMS1_k127_4103877_71 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000000000000000000000124 177.0
CMS1_k127_4103877_72 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000002384 187.0
CMS1_k127_4103877_73 Phospholipid N-methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000009932 178.0
CMS1_k127_4103877_74 Transcriptional regulatory protein, C terminal K14981 - - 0.00000000000000000000000000000000000000000000288 177.0
CMS1_k127_4103877_75 tellurite resistance protein - - - 0.0000000000000000000000000000000000000000003236 169.0
CMS1_k127_4103877_76 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000005769 158.0
CMS1_k127_4103877_77 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000001016 154.0
CMS1_k127_4103877_78 transcriptional regulator - - - 0.0000000000000000000000000000000001962 141.0
CMS1_k127_4103877_79 Cytochrome c - - - 0.000000000000000000000000000000002322 135.0
CMS1_k127_4103877_8 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 607.0
CMS1_k127_4103877_80 Protein of unknown function (DUF2948) - - - 0.0000000000000000000000000000000276 133.0
CMS1_k127_4103877_81 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000002856 127.0
CMS1_k127_4103877_82 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000001377 128.0
CMS1_k127_4103877_83 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000416 133.0
CMS1_k127_4103877_84 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000001931 128.0
CMS1_k127_4103877_85 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.000000000000000000000000004053 122.0
CMS1_k127_4103877_86 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000005105 121.0
CMS1_k127_4103877_87 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000008466 115.0
CMS1_k127_4103877_88 phosphorelay signal transduction system - - - 0.000000000000000000000003289 106.0
CMS1_k127_4103877_89 Protein conserved in bacteria - - - 0.000000000000000000000007913 110.0
CMS1_k127_4103877_9 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 589.0
CMS1_k127_4103877_90 Domain of unknown function (DUF4154) - - - 0.0000000000000000000000662 108.0
CMS1_k127_4103877_91 - - - - 0.00000000000000000000006706 103.0
CMS1_k127_4103877_92 PFAM alpha beta hydrolase fold K18092 - - 0.0000000000000000000001944 110.0
CMS1_k127_4103877_93 Amidohydrolase - - - 0.000000000000000000001312 108.0
CMS1_k127_4103877_94 Cupin 2, conserved barrel domain protein K19547 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0016999,GO:0017000,GO:0017144,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0046872,GO:0046914,GO:0050897 5.3.3.19 0.0000000000000000001398 100.0
CMS1_k127_4103877_95 Amidohydrolase - - - 0.000000000000005434 87.0
CMS1_k127_4103877_96 Putative prokaryotic signal transducing protein - - - 0.0000000000001322 83.0
CMS1_k127_4103877_98 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000003615 72.0
CMS1_k127_4103877_99 - - - - 0.00000000001444 67.0
CMS1_k127_4118763_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1282.0
CMS1_k127_4118763_1 HELICc2 K03722 - 3.6.4.12 0.0 1045.0
CMS1_k127_4118763_10 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 509.0
CMS1_k127_4118763_11 Mg2 and Co2 transporter CorB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 503.0
CMS1_k127_4118763_12 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 492.0
CMS1_k127_4118763_13 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 483.0
CMS1_k127_4118763_14 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 478.0
CMS1_k127_4118763_15 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 467.0
CMS1_k127_4118763_16 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 422.0
CMS1_k127_4118763_17 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 409.0
CMS1_k127_4118763_18 Binding-protein-dependent transport system inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 419.0
CMS1_k127_4118763_19 With CysN catalyzes the formation of adenylylsulfate from sulfate and ATP K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 409.0
CMS1_k127_4118763_2 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 6.7e-296 929.0
CMS1_k127_4118763_20 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 398.0
CMS1_k127_4118763_21 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 386.0
CMS1_k127_4118763_22 Elongation factor Tu GTP binding domain K00956 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 380.0
CMS1_k127_4118763_23 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 358.0
CMS1_k127_4118763_24 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 351.0
CMS1_k127_4118763_25 Amino-transferase class IV K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 348.0
CMS1_k127_4118763_26 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 340.0
CMS1_k127_4118763_27 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 318.0
CMS1_k127_4118763_28 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 317.0
CMS1_k127_4118763_29 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 309.0
CMS1_k127_4118763_3 Pyridine nucleotide-disulphide oxidoreductase - - - 6.87e-262 820.0
CMS1_k127_4118763_30 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 292.0
CMS1_k127_4118763_31 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008386 282.0
CMS1_k127_4118763_32 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005766 278.0
CMS1_k127_4118763_33 SIS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002552 273.0
CMS1_k127_4118763_34 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005542 277.0
CMS1_k127_4118763_35 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006047 271.0
CMS1_k127_4118763_36 sugar phosphatases of the HAD superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001035 276.0
CMS1_k127_4118763_37 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000019 291.0
CMS1_k127_4118763_38 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000001008 271.0
CMS1_k127_4118763_39 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001932 268.0
CMS1_k127_4118763_4 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 2.53e-229 721.0
CMS1_k127_4118763_40 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002238 233.0
CMS1_k127_4118763_41 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000000000000000000000000000000000000000009491 231.0
CMS1_k127_4118763_42 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000000000000000008087 220.0
CMS1_k127_4118763_43 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000001257 218.0
CMS1_k127_4118763_44 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000004546 195.0
CMS1_k127_4118763_45 Domain of unknown function (DUF4115) K15539 - - 0.000000000000000000000000000000000000000000000000008114 195.0
CMS1_k127_4118763_46 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000000000000000000000000003083 192.0
CMS1_k127_4118763_47 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000001417 164.0
CMS1_k127_4118763_48 - - - - 0.0000000000000000000000000000000000000004195 153.0
CMS1_k127_4118763_49 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000001351 161.0
CMS1_k127_4118763_5 COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase) K09883 - 6.6.1.2 1.053e-224 716.0
CMS1_k127_4118763_50 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000001352 134.0
CMS1_k127_4118763_51 Ion channel - - - 0.000000000000000000000000000000001431 135.0
CMS1_k127_4118763_52 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000002922 124.0
CMS1_k127_4118763_53 Belongs to the BolA IbaG family K05527,K22066 - - 0.0000000000000000000000000006112 116.0
CMS1_k127_4118763_54 Protein of unknown function (DUF952) - - - 0.00000000000000000000000000351 114.0
CMS1_k127_4118763_55 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000007842 113.0
CMS1_k127_4118763_56 - - - - 0.00000000000000000000000001507 115.0
CMS1_k127_4118763_57 Ribbon-helix-helix domain - - - 0.000000000000000000006651 96.0
CMS1_k127_4118763_58 Domain of unknown function (DUF4167) - - - 0.00000000000000000001508 98.0
CMS1_k127_4118763_59 Cytochrome C oxidase, cbb3-type, subunit III - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000003467 88.0
CMS1_k127_4118763_6 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 603.0
CMS1_k127_4118763_60 PFAM Glyoxalase bleomycin resistance protein dioxygenase K07104 - 1.13.11.2 0.00000000000000529 82.0
CMS1_k127_4118763_61 Permeases of the major facilitator superfamily - - - 0.00000000003856 75.0
CMS1_k127_4118763_62 Transmembrane secretion effector - - - 0.000000005884 68.0
CMS1_k127_4118763_63 protein conserved in bacteria - - - 0.000003299 58.0
CMS1_k127_4118763_64 - - - - 0.000003652 51.0
CMS1_k127_4118763_7 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 587.0
CMS1_k127_4118763_8 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007975 570.0
CMS1_k127_4118763_9 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 541.0
CMS1_k127_4133847_0 Heat shock 70 kDa protein K04043 - - 0.0 1021.0
CMS1_k127_4133847_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 466.0
CMS1_k127_4133847_2 GrpE K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000009247 96.0
CMS1_k127_4155517_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 462.0
CMS1_k127_4155517_1 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 330.0
CMS1_k127_4155517_2 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000001919 259.0
CMS1_k127_4155517_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000002877 122.0
CMS1_k127_4155517_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000018 76.0
CMS1_k127_4329986_0 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000002921 136.0
CMS1_k127_4329986_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000001711 85.0
CMS1_k127_4329986_2 Sulphur oxidation protein SoxZ K17226 - - 0.0000136 50.0
CMS1_k127_4350735_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1173.0
CMS1_k127_4350735_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1063.0
CMS1_k127_4350735_10 COG0471 Di- and tricarboxylate transporters K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 467.0
CMS1_k127_4350735_11 protein conserved in bacteria K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 457.0
CMS1_k127_4350735_12 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 441.0
CMS1_k127_4350735_13 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 442.0
CMS1_k127_4350735_14 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 400.0
CMS1_k127_4350735_15 FAD dependent oxidoreductase K00273 - 1.4.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 397.0
CMS1_k127_4350735_16 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 357.0
CMS1_k127_4350735_17 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 342.0
CMS1_k127_4350735_18 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 342.0
CMS1_k127_4350735_19 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 309.0
CMS1_k127_4350735_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.367e-228 714.0
CMS1_k127_4350735_20 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 317.0
CMS1_k127_4350735_21 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 302.0
CMS1_k127_4350735_22 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004173 280.0
CMS1_k127_4350735_23 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006373 271.0
CMS1_k127_4350735_24 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000819 264.0
CMS1_k127_4350735_25 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003321 262.0
CMS1_k127_4350735_26 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005841 252.0
CMS1_k127_4350735_27 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000006496 237.0
CMS1_k127_4350735_28 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001627 237.0
CMS1_k127_4350735_29 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000001155 226.0
CMS1_k127_4350735_3 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 6.548e-209 657.0
CMS1_k127_4350735_30 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000001162 216.0
CMS1_k127_4350735_31 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000007082 207.0
CMS1_k127_4350735_32 structural constituent of ribosome K02879 - - 0.0000000000000000000000000000000000000000000000000000000001011 206.0
CMS1_k127_4350735_33 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000002112 208.0
CMS1_k127_4350735_34 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000004433 203.0
CMS1_k127_4350735_35 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000000000000007559 200.0
CMS1_k127_4350735_36 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000005047 190.0
CMS1_k127_4350735_37 Pfam:Ribosomal_L18e K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000006925 189.0
CMS1_k127_4350735_38 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000000002916 182.0
CMS1_k127_4350735_39 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000001365 186.0
CMS1_k127_4350735_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.829e-199 630.0
CMS1_k127_4350735_40 COG5387 Chaperone required for the assembly of the mitochondrial F1-ATPase - - - 0.000000000000000000000000000000000000000000002403 178.0
CMS1_k127_4350735_41 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000009177 169.0
CMS1_k127_4350735_42 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000008095 163.0
CMS1_k127_4350735_43 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000001658 158.0
CMS1_k127_4350735_44 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000000000000459 153.0
CMS1_k127_4350735_45 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000001745 143.0
CMS1_k127_4350735_46 - - - - 0.00000000000000000000000000000000001955 149.0
CMS1_k127_4350735_47 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000001812 142.0
CMS1_k127_4350735_48 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000007792 129.0
CMS1_k127_4350735_49 Protein of unknown function (DUF1489) - - - 0.000000000000000000000000000004675 124.0
CMS1_k127_4350735_5 phosphomannomutase K01840 - 5.4.2.8 2.324e-194 618.0
CMS1_k127_4350735_50 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000005874 117.0
CMS1_k127_4350735_51 Ribosomal protein L30 K02907 - - 0.000000000000000000000008842 104.0
CMS1_k127_4350735_52 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000009368 94.0
CMS1_k127_4350735_53 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000001722 90.0
CMS1_k127_4350735_54 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000001497 73.0
CMS1_k127_4350735_55 MFS_1 like family - - - 0.00000000000885 77.0
CMS1_k127_4350735_56 MFS_1 like family - - - 0.000000001715 70.0
CMS1_k127_4350735_58 MFS_1 like family - - - 0.0000001381 64.0
CMS1_k127_4350735_59 Major Facilitator Superfamily - - - 0.0000006409 62.0
CMS1_k127_4350735_6 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 599.0
CMS1_k127_4350735_60 Major Facilitator Superfamily - - - 0.000005982 61.0
CMS1_k127_4350735_61 PFAM major facilitator superfamily MFS_1 - - - 0.000007915 59.0
CMS1_k127_4350735_62 Major facilitator superfamily K08161 - - 0.0002929 53.0
CMS1_k127_4350735_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 546.0
CMS1_k127_4350735_8 PFAM thiamine pyrophosphate enzyme-like TPP-binding thiamine pyrophosphate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 548.0
CMS1_k127_4350735_9 Belongs to the peptidase S1C family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 501.0
CMS1_k127_4550976_0 Aminotransferase K14261 - - 1.51e-202 642.0
CMS1_k127_4550976_1 ornithine cyclodeaminase K01750 - 4.3.1.12 6.255e-198 623.0
CMS1_k127_4550976_10 aldo-keto reductase (NADP) activity K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 295.0
CMS1_k127_4550976_11 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002095 266.0
CMS1_k127_4550976_12 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000116 238.0
CMS1_k127_4550976_13 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000005138 231.0
CMS1_k127_4550976_14 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000002981 242.0
CMS1_k127_4550976_15 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000004953 230.0
CMS1_k127_4550976_16 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000006059 220.0
CMS1_k127_4550976_17 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000007727 210.0
CMS1_k127_4550976_18 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000002625 210.0
CMS1_k127_4550976_19 Protein of unknown function, DUF481 - - - 0.000000000000000000000000000000000000000000000000001718 197.0
CMS1_k127_4550976_2 COG2873 O-acetylhomoserine sulfhydrylase K01738,K01740 - 2.5.1.47,2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 550.0
CMS1_k127_4550976_20 OmpA family - - - 0.0000000000000000000000000000000000000000000246 175.0
CMS1_k127_4550976_21 - - - - 0.000000000000000000000000000000002157 132.0
CMS1_k127_4550976_22 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000005707 134.0
CMS1_k127_4550976_23 Alpha beta hydrolase - - - 0.0000000000000000000000000000002245 134.0
CMS1_k127_4550976_24 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000233 124.0
CMS1_k127_4550976_25 Polysaccharide deacetylase - - - 0.00000000000000000000999 98.0
CMS1_k127_4550976_26 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000006671 90.0
CMS1_k127_4550976_27 Polysaccharide deacetylase - - - 0.000000000004438 71.0
CMS1_k127_4550976_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 543.0
CMS1_k127_4550976_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 479.0
CMS1_k127_4550976_5 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 446.0
CMS1_k127_4550976_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004194 368.0
CMS1_k127_4550976_7 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 349.0
CMS1_k127_4550976_8 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 340.0
CMS1_k127_4550976_9 COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins K11532 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 324.0
CMS1_k127_4605287_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1144.0
CMS1_k127_4605287_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1092.0
CMS1_k127_4605287_10 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 6.973e-201 633.0
CMS1_k127_4605287_11 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 4.73e-197 633.0
CMS1_k127_4605287_12 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 602.0
CMS1_k127_4605287_13 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 558.0
CMS1_k127_4605287_14 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 510.0
CMS1_k127_4605287_15 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 505.0
CMS1_k127_4605287_16 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 511.0
CMS1_k127_4605287_17 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 481.0
CMS1_k127_4605287_18 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 479.0
CMS1_k127_4605287_19 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 465.0
CMS1_k127_4605287_2 malic enzyme K00029 - 1.1.1.40 0.0 1082.0
CMS1_k127_4605287_20 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 460.0
CMS1_k127_4605287_21 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K09461 - 1.14.13.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008623 451.0
CMS1_k127_4605287_22 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 424.0
CMS1_k127_4605287_23 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 424.0
CMS1_k127_4605287_24 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 412.0
CMS1_k127_4605287_25 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 392.0
CMS1_k127_4605287_26 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 379.0
CMS1_k127_4605287_27 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 394.0
CMS1_k127_4605287_28 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 375.0
CMS1_k127_4605287_29 signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 369.0
CMS1_k127_4605287_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0 1076.0
CMS1_k127_4605287_30 xylanase chitin deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 351.0
CMS1_k127_4605287_31 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 334.0
CMS1_k127_4605287_32 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 338.0
CMS1_k127_4605287_33 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 330.0
CMS1_k127_4605287_34 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 325.0
CMS1_k127_4605287_35 COG1253 Hemolysins and related proteins containing CBS domains K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 314.0
CMS1_k127_4605287_36 FMN-dependent dehydrogenase K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 316.0
CMS1_k127_4605287_37 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 310.0
CMS1_k127_4605287_38 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007457 310.0
CMS1_k127_4605287_39 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 306.0
CMS1_k127_4605287_4 This protein is involved in the repair of mismatches in DNA K03555 - - 0.0 1052.0
CMS1_k127_4605287_40 Sugar (and other) transporter K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008338 302.0
CMS1_k127_4605287_41 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006109 277.0
CMS1_k127_4605287_42 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007804 261.0
CMS1_k127_4605287_43 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000001125 268.0
CMS1_k127_4605287_44 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005087 280.0
CMS1_k127_4605287_45 COG0694 Thioredoxin-like proteins and domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006091 253.0
CMS1_k127_4605287_46 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000003975 249.0
CMS1_k127_4605287_47 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000006346 235.0
CMS1_k127_4605287_48 FlgJ-related protein K03796 - - 0.000000000000000000000000000000000000000000000000000000000000001388 232.0
CMS1_k127_4605287_49 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000003617 212.0
CMS1_k127_4605287_5 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.822e-305 957.0
CMS1_k127_4605287_50 Belongs to the UPF0260 family K09160 - - 0.0000000000000000000000000000000000000000000000000000000002353 220.0
CMS1_k127_4605287_51 ROS/MUCR transcriptional regulator protein - - - 0.0000000000000000000000000000000000000000000000000000000002626 206.0
CMS1_k127_4605287_52 dUTPase K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000000000000000000202 205.0
CMS1_k127_4605287_53 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000002636 200.0
CMS1_k127_4605287_54 Destroys radicals which are normally produced within the cells and which are toxic to biological systems - - - 0.00000000000000000000000000000000000000000000000000008329 194.0
CMS1_k127_4605287_55 Belongs to the Fur family K09826 - - 0.0000000000000000000000000000000000000000000000000001871 188.0
CMS1_k127_4605287_56 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000001037 196.0
CMS1_k127_4605287_57 COG1214 Inactive homolog of metal-dependent proteases K14742 - - 0.000000000000000000000000000000000000000000000000002644 190.0
CMS1_k127_4605287_58 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000001397 184.0
CMS1_k127_4605287_59 protein conserved in bacteria K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000005114 179.0
CMS1_k127_4605287_6 Dioxygenases related to 2-nitropropane dioxygenase K00459 - 1.13.12.16 3.259e-241 754.0
CMS1_k127_4605287_60 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000000000000000001355 187.0
CMS1_k127_4605287_61 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000000001659 185.0
CMS1_k127_4605287_62 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000002905 172.0
CMS1_k127_4605287_63 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000001856 175.0
CMS1_k127_4605287_64 transcriptional - - - 0.000000000000000000000000000000000000000000085 166.0
CMS1_k127_4605287_65 Protein of unknown function (DUF448) K07742 - - 0.000000000000000000000000000000000000000003702 162.0
CMS1_k127_4605287_66 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000004436 155.0
CMS1_k127_4605287_67 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000007806 152.0
CMS1_k127_4605287_68 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000002184 133.0
CMS1_k127_4605287_69 Catalyzes the conversion of maleate to fumarate K01799,K06033 - 4.1.1.76,5.2.1.1 0.00000000000000000000000000000008493 137.0
CMS1_k127_4605287_7 Participates in both transcription termination and antitermination K02600 - - 6.29e-230 724.0
CMS1_k127_4605287_70 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000000000002405 132.0
CMS1_k127_4605287_71 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000235 124.0
CMS1_k127_4605287_72 Isochorismatase family - - - 0.00000000000000000000000000007845 123.0
CMS1_k127_4605287_73 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000003239 107.0
CMS1_k127_4605287_74 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000001167 90.0
CMS1_k127_4605287_75 PQ loop repeat K15383 - - 0.000000000000000002748 100.0
CMS1_k127_4605287_76 - - - - 0.00000000000000006162 85.0
CMS1_k127_4605287_77 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000001418 78.0
CMS1_k127_4605287_78 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.00001132 51.0
CMS1_k127_4605287_8 Cysteine-rich domain - - - 1.073e-217 683.0
CMS1_k127_4605287_9 COG0744 Membrane carboxypeptidase (penicillin-binding protein) K05366 - 2.4.1.129,3.4.16.4 4.628e-201 646.0
CMS1_k127_4777286_0 Aerotolerance regulator N-terminal - - - 9.692e-279 887.0
CMS1_k127_4777286_1 membrane - - - 1.12e-250 793.0
CMS1_k127_4777286_10 Sodium/hydrogen exchanger family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 479.0
CMS1_k127_4777286_11 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 - 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 444.0
CMS1_k127_4777286_12 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 428.0
CMS1_k127_4777286_13 poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 375.0
CMS1_k127_4777286_14 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 361.0
CMS1_k127_4777286_15 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 359.0
CMS1_k127_4777286_16 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 362.0
CMS1_k127_4777286_17 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 343.0
CMS1_k127_4777286_18 Cytochrome C1 family K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 321.0
CMS1_k127_4777286_19 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 319.0
CMS1_k127_4777286_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.779e-231 733.0
CMS1_k127_4777286_20 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 304.0
CMS1_k127_4777286_21 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 295.0
CMS1_k127_4777286_22 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 282.0
CMS1_k127_4777286_23 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001849 276.0
CMS1_k127_4777286_24 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001818 269.0
CMS1_k127_4777286_25 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000002976 264.0
CMS1_k127_4777286_26 transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005977 266.0
CMS1_k127_4777286_27 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000000000000000000000000002432 233.0
CMS1_k127_4777286_28 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000004504 233.0
CMS1_k127_4777286_29 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000001197 235.0
CMS1_k127_4777286_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 3.871e-205 645.0
CMS1_k127_4777286_30 Putative bacterial sensory transduction regulator - - - 0.0000000000000000000000000000000000000000000000000000000000001467 218.0
CMS1_k127_4777286_31 COG0314 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000002045 217.0
CMS1_k127_4777286_32 transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000002623 213.0
CMS1_k127_4777286_33 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000002488 203.0
CMS1_k127_4777286_34 protein conserved in bacteria K09986 - - 0.00000000000000000000000000000000000000000000000001525 184.0
CMS1_k127_4777286_35 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000001088 181.0
CMS1_k127_4777286_36 tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000036 166.0
CMS1_k127_4777286_37 NUDIX domain - - - 0.0000000000000000000000000000000000000009531 162.0
CMS1_k127_4777286_38 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000002053 144.0
CMS1_k127_4777286_39 DoxX K15977 - - 0.00000000000000000000000000000000001499 153.0
CMS1_k127_4777286_4 Tripartite tricarboxylate transporter TctA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 561.0
CMS1_k127_4777286_40 - - - - 0.000000000000000000000000000000003669 139.0
CMS1_k127_4777286_41 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000000000001333 120.0
CMS1_k127_4777286_42 Cold shock K03704 - - 0.0000000000000000000002126 104.0
CMS1_k127_4777286_43 protein conserved in bacteria K09806 - - 0.00000000000002085 85.0
CMS1_k127_4777286_45 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.000000005707 57.0
CMS1_k127_4777286_47 Polysaccharide lyase - - - 0.00001536 55.0
CMS1_k127_4777286_48 - - - - 0.00002116 50.0
CMS1_k127_4777286_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 535.0
CMS1_k127_4777286_6 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 483.0
CMS1_k127_4777286_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 477.0
CMS1_k127_4777286_8 Histidine kinase K07638 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 477.0
CMS1_k127_4777286_9 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 465.0
CMS1_k127_4806713_0 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 323.0
CMS1_k127_4806713_1 protein, possibly involved in utilization of glycolate and propanediol - - - 0.000000000000000000000000000000000000000000882 162.0
CMS1_k127_4806713_2 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.000000000000000000000000000007594 121.0
CMS1_k127_4823087_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2288.0
CMS1_k127_4823087_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.008e-276 865.0
CMS1_k127_4823087_10 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 340.0
CMS1_k127_4823087_11 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006486 332.0
CMS1_k127_4823087_12 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 325.0
CMS1_k127_4823087_13 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 330.0
CMS1_k127_4823087_14 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 GO:0008150,GO:0042221,GO:0046677,GO:0050896 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 305.0
CMS1_k127_4823087_15 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003174 276.0
CMS1_k127_4823087_16 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001572 268.0
CMS1_k127_4823087_17 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004976 240.0
CMS1_k127_4823087_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001815 229.0
CMS1_k127_4823087_19 Protein conserved in bacteria K09774 - - 0.000000000000000000000000000000000000000000000000000000000123 227.0
CMS1_k127_4823087_2 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 - 1.4.1.13,1.4.1.14 2.003e-235 740.0
CMS1_k127_4823087_20 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000002978 202.0
CMS1_k127_4823087_21 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000001258 211.0
CMS1_k127_4823087_22 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000000000000000000001476 179.0
CMS1_k127_4823087_23 surface antigen - - - 0.0000000000000000000000000000000000000000000003596 175.0
CMS1_k127_4823087_24 surface antigen - - - 0.00000000000000000000000000000000000000000005687 174.0
CMS1_k127_4823087_25 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000000000000001525 161.0
CMS1_k127_4823087_26 COG0457 FOG TPR repeat - - - 0.00000000000000000001637 104.0
CMS1_k127_4823087_27 Protein of unknown function (FYDLN_acid) - - - 0.00000000000000007564 86.0
CMS1_k127_4823087_28 Protein of unknown function (DUF1150) - - - 0.000000000000000807 79.0
CMS1_k127_4823087_29 - - - - 0.00000000001749 73.0
CMS1_k127_4823087_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 534.0
CMS1_k127_4823087_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 527.0
CMS1_k127_4823087_5 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 505.0
CMS1_k127_4823087_6 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 462.0
CMS1_k127_4823087_7 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 445.0
CMS1_k127_4823087_8 ABC transporter, ATP-binding protein K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 407.0
CMS1_k127_4823087_9 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 378.0
CMS1_k127_4849275_0 Alanine racemase K20757 - 4.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 366.0
CMS1_k127_4849275_1 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.00000000000003779 76.0
CMS1_k127_4901557_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 585.0
CMS1_k127_4901557_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 431.0
CMS1_k127_4901557_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000002024 238.0
CMS1_k127_4901557_3 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000003834 235.0
CMS1_k127_4901557_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000002231 235.0
CMS1_k127_4901557_5 NnrU protein - - - 0.000000000000000000000000000000000000006686 152.0
CMS1_k127_4901557_6 Major facilitator Superfamily - - - 0.00000000000000000000000000000000003369 149.0
CMS1_k127_4901557_7 YGGT family K02221 - - 0.0000000000000000000000000004259 116.0
CMS1_k127_4901557_8 Belongs to the UPF0235 family K09131 - - 0.000000000009105 70.0
CMS1_k127_4901557_9 Protein of unknown function (DUF1698) K15257 - - 0.00002329 54.0
CMS1_k127_509219_0 Berberine and berberine like - - - 1.042e-236 741.0
CMS1_k127_509219_1 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 589.0
CMS1_k127_509219_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000004871 78.0
CMS1_k127_509219_2 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 585.0
CMS1_k127_509219_3 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005504 569.0
CMS1_k127_509219_4 lysyl-tRNA synthetase K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 439.0
CMS1_k127_509219_5 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 404.0
CMS1_k127_509219_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 304.0
CMS1_k127_509219_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005132 288.0
CMS1_k127_509219_8 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000346 294.0
CMS1_k127_509219_9 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000007222 173.0
CMS1_k127_5348824_0 Belongs to the peptidase S16 family - - - 4.26e-267 846.0
CMS1_k127_5348824_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 7.008e-240 771.0
CMS1_k127_5348824_10 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002043 243.0
CMS1_k127_5348824_11 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000009258 222.0
CMS1_k127_5348824_12 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000007864 214.0
CMS1_k127_5348824_13 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000001781 231.0
CMS1_k127_5348824_14 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000009238 210.0
CMS1_k127_5348824_15 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000001794 198.0
CMS1_k127_5348824_16 low molecular weight K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000009398 184.0
CMS1_k127_5348824_17 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000149 177.0
CMS1_k127_5348824_18 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000001105 183.0
CMS1_k127_5348824_19 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000000000001073 179.0
CMS1_k127_5348824_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 599.0
CMS1_k127_5348824_20 Belongs to the ompA family - - - 0.0000000000000000000000000000000000001573 152.0
CMS1_k127_5348824_21 Pfam:DUF461 K09796 - - 0.00000000000000000000000000000000001052 141.0
CMS1_k127_5348824_22 invasion associated locus B - - - 0.0000000000000000000000000000000001546 138.0
CMS1_k127_5348824_23 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000181 142.0
CMS1_k127_5348824_24 Regulatory protein ArsR - - - 0.0000000000000000000000000000006309 125.0
CMS1_k127_5348824_25 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000005658 64.0
CMS1_k127_5348824_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 488.0
CMS1_k127_5348824_4 FIST N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 319.0
CMS1_k127_5348824_5 Belongs to the BI1 family K06890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 301.0
CMS1_k127_5348824_6 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 293.0
CMS1_k127_5348824_7 ATPases associated with a variety of cellular activities K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 290.0
CMS1_k127_5348824_8 glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 287.0
CMS1_k127_5348824_9 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001494 285.0
CMS1_k127_5409528_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002868 283.0
CMS1_k127_5409528_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000004501 184.0
CMS1_k127_5409528_2 Cupin domain - - - 0.0000001319 53.0
CMS1_k127_5422384_0 COG0480 Translation elongation factors (GTPases) K02355 - - 9.484e-258 811.0
CMS1_k127_5422384_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 601.0
CMS1_k127_5422384_2 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 485.0
CMS1_k127_5422384_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 377.0
CMS1_k127_5422384_4 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 295.0
CMS1_k127_5422384_5 Protein of unknown function (DUF3750) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002151 270.0
CMS1_k127_5422384_6 Psort location Cytoplasmic, score - - - 0.00000000000000005271 90.0
CMS1_k127_5422384_7 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.0000000001178 68.0
CMS1_k127_5482871_0 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000002093 226.0
CMS1_k127_5482871_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000002748 150.0
CMS1_k127_5482871_2 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000004106 134.0
CMS1_k127_5482871_3 - - - - 0.000000000000002515 83.0
CMS1_k127_5482871_4 Bacterial extracellular solute-binding protein K02012 - - 0.000000000001429 79.0
CMS1_k127_5482871_5 Methionine synthase K00549 - 2.1.1.14 0.0002061 44.0
CMS1_k127_5520174_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1234.0
CMS1_k127_5520174_1 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 3.095e-307 959.0
CMS1_k127_5520174_10 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 389.0
CMS1_k127_5520174_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 316.0
CMS1_k127_5520174_12 4Fe-4S dicluster domain K00338,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 293.0
CMS1_k127_5520174_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 289.0
CMS1_k127_5520174_14 Belongs to the complex I subunit 6 family K00339 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000003007 263.0
CMS1_k127_5520174_15 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000001005 249.0
CMS1_k127_5520174_16 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000002279 233.0
CMS1_k127_5520174_17 glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000001542 222.0
CMS1_k127_5520174_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000004101 205.0
CMS1_k127_5520174_19 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000001813 209.0
CMS1_k127_5520174_2 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 8.091e-280 872.0
CMS1_k127_5520174_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000002008 170.0
CMS1_k127_5520174_21 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000000000000000000000000000000000002091 143.0
CMS1_k127_5520174_22 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000000000002256 140.0
CMS1_k127_5520174_23 Protein of unknown function (DUF1467) - - - 0.0000000000000000000000000007894 114.0
CMS1_k127_5520174_24 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000544 122.0
CMS1_k127_5520174_25 - - - - 0.0000000000000002337 84.0
CMS1_k127_5520174_27 Sporulation related domain - - - 0.0001101 52.0
CMS1_k127_5520174_3 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 1.119e-242 758.0
CMS1_k127_5520174_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.028e-229 720.0
CMS1_k127_5520174_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 4.405e-214 669.0
CMS1_k127_5520174_6 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.534e-207 655.0
CMS1_k127_5520174_7 hydrolase of the metallo-beta-lactamase superfamily K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005181 613.0
CMS1_k127_5520174_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 595.0
CMS1_k127_5520174_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 554.0
CMS1_k127_5583080_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.519e-284 889.0
CMS1_k127_5583080_1 CoA-transferase family III K14470 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0015977,GO:0016853,GO:0016866,GO:0016867,GO:0043427,GO:0071704 5.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 520.0
CMS1_k127_5583080_10 UTRA K03710 - - 0.000000000000000000000000000000000000000000001792 175.0
CMS1_k127_5583080_11 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000128 143.0
CMS1_k127_5583080_12 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000001022 94.0
CMS1_k127_5583080_2 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 516.0
CMS1_k127_5583080_3 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 487.0
CMS1_k127_5583080_4 MmgE/PrpD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 498.0
CMS1_k127_5583080_5 MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 414.0
CMS1_k127_5583080_6 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 365.0
CMS1_k127_5583080_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 317.0
CMS1_k127_5583080_8 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001188 270.0
CMS1_k127_5583080_9 Pfam:AmoA K07120 - - 0.0000000000000000000000000000000000000000000000000000000000006126 224.0
CMS1_k127_5588781_0 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 402.0
CMS1_k127_5588781_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 305.0
CMS1_k127_5588781_2 Lysophospholipase - - - 0.000000000000000000000000000000000000000000000000000209 198.0
CMS1_k127_5588781_3 Zinc-finger domain - - - 0.000000000001161 73.0
CMS1_k127_5619064_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 3.135e-250 783.0
CMS1_k127_5619064_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 2.452e-238 744.0
CMS1_k127_5619064_10 dioxygenase alpha subunit K16319,K18242 - 1.14.12.1,1.14.13.172 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 448.0
CMS1_k127_5619064_11 Transport permease protein K01992 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 414.0
CMS1_k127_5619064_12 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 399.0
CMS1_k127_5619064_13 4-hydroxy-tetrahydrodipicolinate synthase K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008129 390.0
CMS1_k127_5619064_14 Reductase C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 395.0
CMS1_k127_5619064_15 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 370.0
CMS1_k127_5619064_16 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 307.0
CMS1_k127_5619064_17 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000217 291.0
CMS1_k127_5619064_18 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006286 286.0
CMS1_k127_5619064_19 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000009859 264.0
CMS1_k127_5619064_2 Pyridine nucleotide-disulphide oxidoreductase - - - 8.905e-215 685.0
CMS1_k127_5619064_20 Phytanoyl-CoA dioxygenase PhyH family protein - - - 0.000000000000000000000000000000000000000000000000000000007835 209.0
CMS1_k127_5619064_21 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000002792 193.0
CMS1_k127_5619064_22 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000007458 188.0
CMS1_k127_5619064_23 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000002567 188.0
CMS1_k127_5619064_24 Ring hydroxylating beta subunit K16320 - 1.14.12.1 0.0000000000000000000000000000000000000002229 158.0
CMS1_k127_5619064_25 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000007557 158.0
CMS1_k127_5619064_26 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000009204 170.0
CMS1_k127_5619064_27 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000004168 153.0
CMS1_k127_5619064_28 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000003216 149.0
CMS1_k127_5619064_29 Rieske-like [2Fe-2S] domain K05710 - - 0.00000000000000000000000000000005821 127.0
CMS1_k127_5619064_3 Sulfite reductase K00381 - 1.8.1.2 3.598e-196 635.0
CMS1_k127_5619064_30 ThiS family - - - 0.00000000000000000000000003384 111.0
CMS1_k127_5619064_31 - - - - 0.00000000131 65.0
CMS1_k127_5619064_32 PFAM regulatory protein, MarR - - - 0.0000004577 62.0
CMS1_k127_5619064_34 NlpC/P60 family K21471 - - 0.00001046 53.0
CMS1_k127_5619064_35 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.0008813 49.0
CMS1_k127_5619064_4 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009545 580.0
CMS1_k127_5619064_5 TRAP transporter, 4TM 12TM fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007296 531.0
CMS1_k127_5619064_6 ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 472.0
CMS1_k127_5619064_7 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 460.0
CMS1_k127_5619064_8 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 467.0
CMS1_k127_5619064_9 PFAM Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 456.0
CMS1_k127_564829_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.651e-310 961.0
CMS1_k127_564829_1 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 344.0
CMS1_k127_564829_2 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000005686 177.0
CMS1_k127_564829_3 Belongs to the BolA IbaG family - - - 0.000000000000000000000003129 119.0
CMS1_k127_564829_4 Sh3 type 3 domain protein - - - 0.000000000000002285 85.0
CMS1_k127_564829_5 - - - - 0.00000000000001038 78.0
CMS1_k127_5671334_0 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 312.0
CMS1_k127_5671334_1 PFAM isochorismatase hydrolase - - - 0.0000000000000000000000000000484 117.0
CMS1_k127_5703270_0 Penicillin amidase K01434 - 3.5.1.11 3.277e-218 703.0
CMS1_k127_5703270_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.097e-214 673.0
CMS1_k127_5703270_10 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 349.0
CMS1_k127_5703270_11 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 336.0
CMS1_k127_5703270_12 riboflavin synthase, alpha subunit K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000003325 245.0
CMS1_k127_5703270_13 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000000004505 237.0
CMS1_k127_5703270_14 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000003823 241.0
CMS1_k127_5703270_15 COG0698 Ribose 5-phosphate isomerase RpiB K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000001592 204.0
CMS1_k127_5703270_16 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000000027 194.0
CMS1_k127_5703270_17 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000003214 188.0
CMS1_k127_5703270_18 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000006719 145.0
CMS1_k127_5703270_19 Trypsin K08070 - 1.3.1.74 0.00000000000000000009906 93.0
CMS1_k127_5703270_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 495.0
CMS1_k127_5703270_3 With LivFGHM is involved in the high affinity leucine transport K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 477.0
CMS1_k127_5703270_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 456.0
CMS1_k127_5703270_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 451.0
CMS1_k127_5703270_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 446.0
CMS1_k127_5703270_7 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 440.0
CMS1_k127_5703270_8 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 349.0
CMS1_k127_5703270_9 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 342.0
CMS1_k127_5875198_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1100.0
CMS1_k127_5875198_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 458.0
CMS1_k127_5875198_10 Protein conserved in bacteria K09780 - - 0.00000000000000000000001457 102.0
CMS1_k127_5875198_11 Rieske 2Fe-2S - - - 0.0000000000000000009716 94.0
CMS1_k127_5875198_2 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 402.0
CMS1_k127_5875198_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 346.0
CMS1_k127_5875198_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 311.0
CMS1_k127_5875198_5 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008832 295.0
CMS1_k127_5875198_6 Putative 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000000000000000000009207 208.0
CMS1_k127_5875198_7 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000003708 196.0
CMS1_k127_5875198_8 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.00000000000000000000000000000000000000001029 164.0
CMS1_k127_5875198_9 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000001635 133.0
CMS1_k127_5895813_0 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 528.0
CMS1_k127_5895813_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244,K19743 - 1.4.1.1,1.5.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 442.0
CMS1_k127_5895813_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000001688 93.0
CMS1_k127_5895813_3 COG0859 ADP-heptose LPS heptosyltransferase - - - 0.000000000000000002085 89.0
CMS1_k127_5895813_4 (LPS) heptosyltransferase - - - 0.000000002799 60.0
CMS1_k127_6007257_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 8.571e-244 771.0
CMS1_k127_6007257_1 Enoyl-CoA hydratase/isomerase - - - 1.596e-242 760.0
CMS1_k127_6007257_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000004881 166.0
CMS1_k127_6007257_11 Uncharacterized protein conserved in bacteria (DUF2199) - - - 0.000000000000000002809 87.0
CMS1_k127_6007257_12 Uncharacterized protein conserved in bacteria (DUF2199) - - - 0.0000003612 55.0
CMS1_k127_6007257_2 Belongs to the thiolase family K00626,K00632,K07823 - 2.3.1.16,2.3.1.174,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 586.0
CMS1_k127_6007257_3 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 463.0
CMS1_k127_6007257_4 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 374.0
CMS1_k127_6007257_5 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003464 269.0
CMS1_k127_6007257_6 Acyl-CoA dehydrogenase, C-terminal domain K16047,K20942 - 1.14.14.12,1.14.14.27 0.00000000000000000000000000000000000000000000000000000000000000000003701 247.0
CMS1_k127_6007257_7 Enoyl-CoA hydratase K01692,K08299 - 4.2.1.149,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000005333 222.0
CMS1_k127_6007257_8 Domain of unknown function (DUF4863) - - - 0.000000000000000000000000000000000000000000000000000000000009335 210.0
CMS1_k127_6007257_9 transcriptional regulator - - - 0.000000000000000000000000000000000000000000004725 174.0
CMS1_k127_6091902_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1094.0
CMS1_k127_6091902_1 Belongs to the UbiD family K03182 - 4.1.1.98 9.731e-224 707.0
CMS1_k127_6091902_10 Rieske (2Fe-2S) domain-containing protein K15060 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 402.0
CMS1_k127_6091902_11 ABC-type Fe3 transport system permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 372.0
CMS1_k127_6091902_12 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 351.0
CMS1_k127_6091902_13 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 352.0
CMS1_k127_6091902_14 ABC-type Fe3 transport system permease component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 365.0
CMS1_k127_6091902_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 342.0
CMS1_k127_6091902_16 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 332.0
CMS1_k127_6091902_17 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 336.0
CMS1_k127_6091902_18 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 325.0
CMS1_k127_6091902_19 Belongs to the ABC transporter superfamily K02010,K02052 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 318.0
CMS1_k127_6091902_2 5-oxoprolinase K01473 - 3.5.2.14 1.655e-216 692.0
CMS1_k127_6091902_20 taurine catabolism dioxygenase K03119,K22303 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 301.0
CMS1_k127_6091902_21 Belongs to the ABC transporter superfamily K02010,K02052 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 314.0
CMS1_k127_6091902_22 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 295.0
CMS1_k127_6091902_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001465 274.0
CMS1_k127_6091902_25 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006173 264.0
CMS1_k127_6091902_26 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006585 261.0
CMS1_k127_6091902_27 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001038 246.0
CMS1_k127_6091902_28 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001072 256.0
CMS1_k127_6091902_29 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001222 256.0
CMS1_k127_6091902_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.393e-207 661.0
CMS1_k127_6091902_30 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000001798 241.0
CMS1_k127_6091902_31 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000004185 251.0
CMS1_k127_6091902_32 PFAM Dimethylmenaquinone methyltransferase K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000704 231.0
CMS1_k127_6091902_33 PFAM Dimethylmenaquinone methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000002757 218.0
CMS1_k127_6091902_34 Amidohydrolase K10220 - 4.2.1.83 0.000000000000000000000000000000000000000000000000000000000001019 228.0
CMS1_k127_6091902_35 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000001092 220.0
CMS1_k127_6091902_36 FCD - - - 0.00000000000000000000000000000000000000000000000000000003229 207.0
CMS1_k127_6091902_37 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000003512 206.0
CMS1_k127_6091902_38 Protein of unknown function (DUF1194) - - - 0.0000000000000000000000000000000000000000000000000000005122 201.0
CMS1_k127_6091902_39 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000001247 205.0
CMS1_k127_6091902_4 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 590.0
CMS1_k127_6091902_40 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000008902 194.0
CMS1_k127_6091902_41 iron ion homeostasis K02012 - - 0.000000000000000000000000000000000000000000000003437 189.0
CMS1_k127_6091902_42 Class II aldolase K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000001086 173.0
CMS1_k127_6091902_43 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000003752 169.0
CMS1_k127_6091902_44 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000001775 165.0
CMS1_k127_6091902_45 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000004666 158.0
CMS1_k127_6091902_46 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.000000000000000000000000000000000000008366 157.0
CMS1_k127_6091902_47 iron ion homeostasis K02012 - - 0.00000000000000000000000000000000008528 147.0
CMS1_k127_6091902_48 protein conserved in bacteria - - - 0.0000000000000000000000000000000006272 146.0
CMS1_k127_6091902_49 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000005041 133.0
CMS1_k127_6091902_5 Thiamine pyrophosphate enzyme, central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 587.0
CMS1_k127_6091902_50 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000004032 104.0
CMS1_k127_6091902_51 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000007711 105.0
CMS1_k127_6091902_52 Class II aldolase adducin family protein K18256 - 4.1.1.69 0.0000000000000001352 90.0
CMS1_k127_6091902_53 Protein of unknwon function (DUF3008) - - - 0.00000000000004836 73.0
CMS1_k127_6091902_54 Amidohydrolase - - - 0.0000000000008535 73.0
CMS1_k127_6091902_55 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000000127 74.0
CMS1_k127_6091902_56 Bacterial extracellular solute-binding protein K02012 - - 0.0000000001558 74.0
CMS1_k127_6091902_57 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000004138 61.0
CMS1_k127_6091902_6 COG3653 N-acyl-D-aspartate D-glutamate deacylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 580.0
CMS1_k127_6091902_7 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 513.0
CMS1_k127_6091902_8 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 501.0
CMS1_k127_6091902_9 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 415.0
CMS1_k127_624667_0 Tripartite tricarboxylate transporter TctA family - - - 4.244e-256 805.0
CMS1_k127_624667_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.034e-230 725.0
CMS1_k127_624667_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000009493 171.0
CMS1_k127_624667_11 Sugar-transfer associated ATP-grasp - - - 0.00000000000000000000000000000000000246 140.0
CMS1_k127_624667_12 - - - - 0.0000000000000000000000000000689 133.0
CMS1_k127_624667_13 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000004342 119.0
CMS1_k127_624667_14 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000001068 114.0
CMS1_k127_624667_15 Dienelactone hydrolase family - - - 0.0000000000738 68.0
CMS1_k127_624667_16 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.0000007262 63.0
CMS1_k127_624667_17 Protein of unknown function (DUF2919) - - - 0.000006483 55.0
CMS1_k127_624667_18 Tetratricopeptide repeat - - - 0.0002413 54.0
CMS1_k127_624667_2 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit K13796 - - 5.072e-195 617.0
CMS1_k127_624667_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 463.0
CMS1_k127_624667_4 TIGRFAM CitB domain protein K13795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 414.0
CMS1_k127_624667_5 PrpF protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 421.0
CMS1_k127_624667_6 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 329.0
CMS1_k127_624667_7 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008594 271.0
CMS1_k127_624667_8 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000001419 226.0
CMS1_k127_624667_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000007938 211.0
CMS1_k127_6261591_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.156e-223 702.0
CMS1_k127_6261591_1 Mmge prpd family - - - 1.828e-209 660.0
CMS1_k127_6261591_10 metal-dependent hydrolase of the TIM-barrel fold - - - 0.000000000000000000000000000000000001069 152.0
CMS1_k127_6261591_11 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000000000000000000000000000005515 134.0
CMS1_k127_6261591_12 Class II aldolase K01628 - 4.1.2.17 0.0000000000000001739 89.0
CMS1_k127_6261591_13 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000006265 65.0
CMS1_k127_6261591_15 Putative peptidoglycan binding domain - - - 0.00003155 55.0
CMS1_k127_6261591_2 acyl-CoA transferases carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 449.0
CMS1_k127_6261591_3 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 431.0
CMS1_k127_6261591_4 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 373.0
CMS1_k127_6261591_5 PFAM Mandelate racemase muconate lactonizing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 364.0
CMS1_k127_6261591_6 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 322.0
CMS1_k127_6261591_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 322.0
CMS1_k127_6261591_8 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005501 273.0
CMS1_k127_6261591_9 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005241 256.0
CMS1_k127_730628_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 5.901e-195 618.0
CMS1_k127_730628_1 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 545.0
CMS1_k127_730628_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 330.0
CMS1_k127_730628_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 326.0
CMS1_k127_730628_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 324.0
CMS1_k127_730628_5 metal ion transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001869 274.0
CMS1_k127_767817_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1610.0
CMS1_k127_767817_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 495.0
CMS1_k127_767817_2 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 431.0
CMS1_k127_767817_3 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 417.0
CMS1_k127_767817_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000003085 231.0
CMS1_k127_767817_5 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000000000000000000000005153 218.0
CMS1_k127_767817_6 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000002164 164.0
CMS1_k127_78356_0 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 1.621e-299 972.0
CMS1_k127_78356_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.632e-218 683.0
CMS1_k127_78356_10 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000002145 163.0
CMS1_k127_78356_11 Lipopolysaccharide assembly protein A domain K08992 - - 0.0000000002988 66.0
CMS1_k127_78356_2 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 510.0
CMS1_k127_78356_3 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 428.0
CMS1_k127_78356_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 427.0
CMS1_k127_78356_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 367.0
CMS1_k127_78356_6 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 307.0
CMS1_k127_78356_7 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000002398 266.0
CMS1_k127_78356_8 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000002229 231.0
CMS1_k127_78356_9 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000004653 171.0
CMS1_k127_938765_0 NAD-specific glutamate dehydrogenase K15371 - 1.4.1.2 5.557e-250 790.0
CMS1_k127_938765_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 4.032e-234 735.0
CMS1_k127_938765_2 Polysaccharide biosynthesis protein K13013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 627.0
CMS1_k127_938765_3 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 505.0
CMS1_k127_938765_4 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 497.0
CMS1_k127_938765_5 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 430.0
CMS1_k127_938765_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 423.0
CMS1_k127_938765_7 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 339.0
CMS1_k127_938765_8 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase K02851,K13007 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 296.0
CMS1_k127_938765_9 FAD-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000009955 223.0
CMS1_k127_989551_0 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 - 1.2.4.2 0.0 1343.0
CMS1_k127_989551_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 5.31e-308 951.0
CMS1_k127_989551_10 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 561.0
CMS1_k127_989551_11 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 539.0
CMS1_k127_989551_12 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 513.0
CMS1_k127_989551_13 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 509.0
CMS1_k127_989551_14 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 502.0
CMS1_k127_989551_15 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 486.0
CMS1_k127_989551_16 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 493.0
CMS1_k127_989551_17 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 457.0
CMS1_k127_989551_18 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 462.0
CMS1_k127_989551_19 AFG1-like ATPase K06916 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 440.0
CMS1_k127_989551_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.731e-276 867.0
CMS1_k127_989551_20 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 382.0
CMS1_k127_989551_21 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 368.0
CMS1_k127_989551_22 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 331.0
CMS1_k127_989551_23 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 326.0
CMS1_k127_989551_24 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 324.0
CMS1_k127_989551_25 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 326.0
CMS1_k127_989551_26 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 306.0
CMS1_k127_989551_27 HpcH/HpaI aldolase/citrate lyase family K01644,K14451 - 3.1.2.30,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 293.0
CMS1_k127_989551_28 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 291.0
CMS1_k127_989551_29 protein conserved in bacteria K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001772 286.0
CMS1_k127_989551_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.236e-275 852.0
CMS1_k127_989551_30 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000005413 266.0
CMS1_k127_989551_31 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000202 241.0
CMS1_k127_989551_32 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000006641 222.0
CMS1_k127_989551_33 COG4942 Membrane-bound metallopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000005974 230.0
CMS1_k127_989551_34 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000016 215.0
CMS1_k127_989551_35 protein conserved in bacteria K09921 - - 0.0000000000000000000000000000000000000000000000000000009094 207.0
CMS1_k127_989551_36 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000005408 184.0
CMS1_k127_989551_37 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000003513 168.0
CMS1_k127_989551_38 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000003638 179.0
CMS1_k127_989551_39 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.0000000000000000000000000000000000000000001497 163.0
CMS1_k127_989551_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.453e-265 821.0
CMS1_k127_989551_40 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000005319 163.0
CMS1_k127_989551_41 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000002185 147.0
CMS1_k127_989551_42 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000009102 152.0
CMS1_k127_989551_43 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000003036 156.0
CMS1_k127_989551_44 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000000000001094 155.0
CMS1_k127_989551_45 Carboxymethylenebutenolidase K01061 - 3.1.1.45 0.0000000000000000000000000000000000004101 156.0
CMS1_k127_989551_46 ornithine cyclodeaminase activity K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000003095 154.0
CMS1_k127_989551_47 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000001805 136.0
CMS1_k127_989551_48 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000001049 141.0
CMS1_k127_989551_49 Succinate dehydrogenase, hydrophobic anchor subunit K00242 - - 0.00000000000000000000000000000003031 135.0
CMS1_k127_989551_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.559e-234 733.0
CMS1_k127_989551_50 Putative transmembrane protein (PGPGW) - - - 0.00000008984 57.0
CMS1_k127_989551_51 receptor - - - 0.000001692 56.0
CMS1_k127_989551_6 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 2.784e-211 668.0
CMS1_k127_989551_7 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 8.575e-195 619.0
CMS1_k127_989551_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 7.916e-194 610.0
CMS1_k127_989551_9 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 583.0