Overview

ID MAG00407
Name CMS2_bin.102
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Rhodospirillales
Family Magnetovibrionaceae
Genus JANLGW01
Species
Assembly information
Completeness (%) 83.05
Contamination (%) 4.82
GC content (%) 60.0
N50 (bp) 5,822
Genome size (bp) 2,234,797

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2337

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1011371_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 566.0
CMS2_k127_1014424_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 304.0
CMS2_k127_1014424_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000167 189.0
CMS2_k127_1014424_2 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000005641 156.0
CMS2_k127_1014424_3 - - - - 0.00000002019 59.0
CMS2_k127_1023949_0 Proton-conducting membrane transporter K05568 - - 1.237e-226 715.0
CMS2_k127_1023949_1 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K00341,K05568 - 1.6.5.3 1.053e-196 624.0
CMS2_k127_1023949_2 Proton-conducting membrane transporter K00343,K05568 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 572.0
CMS2_k127_1023949_3 amino acid K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 307.0
CMS2_k127_1023949_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000000000000000000000000000003571 166.0
CMS2_k127_1023949_5 Na H antiporter, MnhB - - - 0.000000000000000001522 86.0
CMS2_k127_1039038_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 4.136e-196 620.0
CMS2_k127_1039038_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 475.0
CMS2_k127_1039038_2 membrane protein, required for colicin V production K03558 - - 0.0000000000000000000000000000000000000002197 158.0
CMS2_k127_1061621_0 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 1.876e-223 704.0
CMS2_k127_1061621_1 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000005308 209.0
CMS2_k127_1061621_2 Cation transporter/ATPase, N-terminus K01537,K01539 - 3.6.3.8,3.6.3.9 0.000000000000000000000000000000000000000009189 156.0
CMS2_k127_1061621_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000008714 149.0
CMS2_k127_1110833_0 Bacterial NAD-glutamate dehydrogenase K15371 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 0.000000000000000000000000000000000000000000000000000000004775 209.0
CMS2_k127_1110833_1 - - - - 0.000000000001551 72.0
CMS2_k127_1110833_2 basal body P-ring K02386 - - 0.000001973 53.0
CMS2_k127_1115345_0 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 488.0
CMS2_k127_1115345_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 312.0
CMS2_k127_1115345_2 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006871 267.0
CMS2_k127_1120886_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1076.0
CMS2_k127_1120886_1 arginine decarboxylase K01585 - 4.1.1.19 2.111e-259 814.0
CMS2_k127_1120886_10 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000002164 118.0
CMS2_k127_1120886_11 Putative FMN-binding domain K07734 - - 0.0000000000000000000000000002232 122.0
CMS2_k127_1120886_2 Arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 537.0
CMS2_k127_1120886_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 340.0
CMS2_k127_1120886_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 310.0
CMS2_k127_1120886_5 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001687 260.0
CMS2_k127_1120886_6 Glutaredoxin K07390 - - 0.00000000000000000000000000000000000000000000000001068 182.0
CMS2_k127_1120886_7 HPP family - - - 0.00000000000000000000000000000000000000000000665 168.0
CMS2_k127_1120886_8 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000000000000000000000000001057 130.0
CMS2_k127_1120886_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000001299 130.0
CMS2_k127_1125314_0 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000001814 196.0
CMS2_k127_1125314_1 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000000000000001254 203.0
CMS2_k127_1125314_2 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000001014 139.0
CMS2_k127_1125314_3 Flp/Fap pilin component K02651 - - 0.000000000006664 68.0
CMS2_k127_1139146_0 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 472.0
CMS2_k127_1139146_1 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 462.0
CMS2_k127_1139146_2 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000003807 215.0
CMS2_k127_1139146_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.00000000000000000000000000000000000000000000000000000000001901 208.0
CMS2_k127_1167869_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 9.211e-230 717.0
CMS2_k127_1167869_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000003248 163.0
CMS2_k127_1192900_0 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000355 215.0
CMS2_k127_1192900_2 EAL domain - - - 0.0000008977 53.0
CMS2_k127_1193409_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 3.692e-215 676.0
CMS2_k127_1193409_1 4Fe-4S dicluster domain K00184,K21308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 389.0
CMS2_k127_1193409_2 DMSO reductase anchor subunit K21309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 347.0
CMS2_k127_1193409_3 transport system periplasmic component K07080 - - 0.00000000000007755 71.0
CMS2_k127_119847_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 4.521e-221 697.0
CMS2_k127_119847_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 555.0
CMS2_k127_119847_2 Periplasmic binding protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 355.0
CMS2_k127_119847_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 325.0
CMS2_k127_119847_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000003409 207.0
CMS2_k127_1246665_0 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 486.0
CMS2_k127_1246665_1 octanoyl transferase activity (acting on glycine-cleavage complex H protein) K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 308.0
CMS2_k127_1246665_2 chemotaxis protein - - - 0.000000000000000000000000000000000001905 145.0
CMS2_k127_1246665_3 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000000000004409 109.0
CMS2_k127_1246665_4 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.0000003863 57.0
CMS2_k127_1246665_5 cheY-homologous receiver domain - - - 0.00000817 51.0
CMS2_k127_1250441_0 D-ala-D-ala dipeptidase K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008364 282.0
CMS2_k127_1250441_1 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000003518 188.0
CMS2_k127_1250441_2 COG1214 Inactive homolog of metal-dependent proteases K14742 - - 0.00000000000000000000000000000000000000000002763 166.0
CMS2_k127_1259846_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 618.0
CMS2_k127_1259846_1 Cold shock K03704 - - 0.00000000000000000000000000575 111.0
CMS2_k127_1259846_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.0000000000000003374 79.0
CMS2_k127_1261671_0 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000007189 237.0
CMS2_k127_1261671_1 COG1463 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000003722 180.0
CMS2_k127_1261671_2 NADH ubiquinone oxidoreductase subunit NDUFA12 K00356 - 1.6.99.3 0.0000000000000000000000000000000000000000002967 167.0
CMS2_k127_1261671_3 COG0695 Glutaredoxin and related proteins - - - 0.0000000000000000000000000000000000000004272 152.0
CMS2_k127_1261671_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000001019 156.0
CMS2_k127_1261671_5 MlaD protein K02067 - - 0.000000000000000000000000000000315 128.0
CMS2_k127_1261671_6 protein conserved in bacteria - - - 0.00000000000000000000000002365 110.0
CMS2_k127_1274787_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 349.0
CMS2_k127_1274787_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004408 278.0
CMS2_k127_1274787_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000003956 219.0
CMS2_k127_1274787_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000003584 208.0
CMS2_k127_1274787_4 Ribosomal protein L7/L12 dimerisation domain K02935 - - 0.000000000000000000000000000000000000000000004465 166.0
CMS2_k127_1274787_5 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000003437 88.0
CMS2_k127_1284832_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1229.0
CMS2_k127_1284832_1 PCRF K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 491.0
CMS2_k127_1284832_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 380.0
CMS2_k127_1284832_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000002664 256.0
CMS2_k127_1284832_4 MOSC domain K07140 - - 0.00000000000000000000000000000000000000000000001523 180.0
CMS2_k127_1284832_5 GcpE protein K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000002303 109.0
CMS2_k127_1284832_6 Domain of unknown function (DUF4167) - - - 0.0000000000000000192 91.0
CMS2_k127_1366744_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1263.0
CMS2_k127_1366744_1 Molecular chaperone. Has ATPase activity K04079 - - 2.441e-268 839.0
CMS2_k127_1366744_10 TadE-like protein K02651 - - 0.0000000000000000000002746 109.0
CMS2_k127_1366744_11 Flp pilus assembly protein TadG - - - 0.00000000000000000003046 97.0
CMS2_k127_1366744_12 Protein of unknown function (DUF3012) - - - 0.000000000000009593 76.0
CMS2_k127_1366744_2 COG0513 Superfamily II DNA and RNA helicases K17675 - 3.6.4.13 5.187e-257 818.0
CMS2_k127_1366744_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 289.0
CMS2_k127_1366744_4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002114 276.0
CMS2_k127_1366744_5 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000415 280.0
CMS2_k127_1366744_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000007236 209.0
CMS2_k127_1366744_7 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000001216 134.0
CMS2_k127_1366744_8 ERAD pathway - - - 0.0000000000000000000000004412 113.0
CMS2_k127_1366744_9 COG1544 Ribosome-associated protein Y (PSrp-1) - - - 0.000000000000000000000003004 108.0
CMS2_k127_1381066_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 1.225e-194 620.0
CMS2_k127_1381066_1 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000000000000000001349 143.0
CMS2_k127_1383685_0 cobalamin synthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 362.0
CMS2_k127_1383685_1 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359 - 0.0000000006081 67.0
CMS2_k127_1383685_2 PFAM secretion protein HlyD family protein K02005,K02022 - - 0.0001317 49.0
CMS2_k127_1383758_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1430.0
CMS2_k127_1383758_1 Belongs to the UbiD family K03182 - 4.1.1.98 3.881e-276 856.0
CMS2_k127_1383758_2 HD domain - - - 1.096e-226 718.0
CMS2_k127_1383758_3 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 576.0
CMS2_k127_1383758_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000003674 230.0
CMS2_k127_1383758_5 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000006547 153.0
CMS2_k127_1383758_6 - - - - 0.000001469 53.0
CMS2_k127_1387511_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 306.0
CMS2_k127_1387511_1 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000065 274.0
CMS2_k127_1392873_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 7.487e-320 987.0
CMS2_k127_1392873_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 511.0
CMS2_k127_1392873_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 287.0
CMS2_k127_1392873_3 4Fe-4S dicluster domain K00196,K05796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004989 243.0
CMS2_k127_1400559_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 582.0
CMS2_k127_1400559_1 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 554.0
CMS2_k127_1407526_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 1.498e-199 628.0
CMS2_k127_1407526_1 Sulfurtransferase TusA - - - 0.00000000000000000000000000007684 117.0
CMS2_k127_1407526_3 DsrE/DsrF/DrsH-like family - - - 0.0000000008418 59.0
CMS2_k127_1410651_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 2.75e-321 1002.0
CMS2_k127_1410651_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 495.0
CMS2_k127_1410651_2 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 402.0
CMS2_k127_1434924_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 430.0
CMS2_k127_1434924_1 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000002532 131.0
CMS2_k127_1436582_0 Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 503.0
CMS2_k127_1436582_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 391.0
CMS2_k127_1436582_2 Putative heavy-metal chelation K09138 - - 0.00000000000000000000000000000000000001625 150.0
CMS2_k127_1478568_0 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000000000000000002531 90.0
CMS2_k127_1478568_1 - - - - 0.000000000000003557 79.0
CMS2_k127_1478568_2 oligosaccharyl transferase activity - - - 0.00000000001137 71.0
CMS2_k127_1489436_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 5.77e-236 739.0
CMS2_k127_1489436_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 2.87e-221 693.0
CMS2_k127_1489436_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000635 593.0
CMS2_k127_1489436_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 533.0
CMS2_k127_1489436_4 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000003866 147.0
CMS2_k127_1489436_5 - - - - 0.000000000000000000000000000003063 120.0
CMS2_k127_1489436_6 Excinuclease ABC, C subunit K07461 - - 0.00000000000000000000000001345 110.0
CMS2_k127_1495540_0 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 537.0
CMS2_k127_1495540_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 475.0
CMS2_k127_1499361_0 Aminotransferase class-V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 526.0
CMS2_k127_1499361_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0000096,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006464,GO:0006520,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0018282,GO:0018283,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0031071,GO:0031163,GO:0031974,GO:0031981,GO:0032324,GO:0034641,GO:0036211,GO:0042278,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 337.0
CMS2_k127_1499361_2 serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000001777 238.0
CMS2_k127_1499361_3 transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000000000000000000006181 205.0
CMS2_k127_1517718_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 320.0
CMS2_k127_1517718_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000003655 197.0
CMS2_k127_1517718_2 cell redox homeostasis - - - 0.0000000000000000000000000000000000000008835 158.0
CMS2_k127_1517718_3 - - - - 0.0000000000000000000000000000000002202 138.0
CMS2_k127_1517718_4 YsiA-like protein, C-terminal region - - - 0.0000000000000000000007793 97.0
CMS2_k127_1517718_6 FecR protein - - - 0.0000000000000000001766 98.0
CMS2_k127_1517718_7 ergosterol biosynthetic process K02291 - 2.5.1.32,2.5.1.99 0.00000000000000005092 90.0
CMS2_k127_152850_0 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 440.0
CMS2_k127_152850_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000007282 168.0
CMS2_k127_1539355_0 NusA-like KH domain K02600 - - 1.584e-234 736.0
CMS2_k127_1539355_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 7.98e-200 629.0
CMS2_k127_1539355_10 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000037 190.0
CMS2_k127_1539355_11 transcriptional - - - 0.00000000000000000000000000000000000000000000000007493 181.0
CMS2_k127_1539355_12 COG1214 Inactive homolog of metal-dependent proteases K14742 - - 0.0000000000000000000000000000000000000000002297 167.0
CMS2_k127_1539355_13 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000000003275 156.0
CMS2_k127_1539355_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000366 156.0
CMS2_k127_1539355_15 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000001274 115.0
CMS2_k127_1539355_16 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000000007696 106.0
CMS2_k127_1539355_17 D-ala-D-ala dipeptidase K08641 - 3.4.13.22 0.00000000000007407 75.0
CMS2_k127_1539355_18 Belongs to the Fur family K03711 - - 0.0000000003246 62.0
CMS2_k127_1539355_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 588.0
CMS2_k127_1539355_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009611 455.0
CMS2_k127_1539355_4 AAA domain K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 391.0
CMS2_k127_1539355_5 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 383.0
CMS2_k127_1539355_6 COG1253 Hemolysins and related proteins containing CBS domains K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 318.0
CMS2_k127_1539355_7 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000008553 263.0
CMS2_k127_1539355_8 ROS/MUCR transcriptional regulator protein - - - 0.00000000000000000000000000000000000000000000000000000000001733 208.0
CMS2_k127_1539355_9 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.000000000000000000000000000000000000000000000000000003418 197.0
CMS2_k127_155058_0 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 333.0
CMS2_k127_155058_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 327.0
CMS2_k127_155058_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000002113 222.0
CMS2_k127_155058_3 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000001591 161.0
CMS2_k127_155058_4 - - - - 0.00000000000000004548 84.0
CMS2_k127_158023_0 Oxidoreductase family, C-terminal alpha/beta domain K13016 - 1.1.1.335 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 468.0
CMS2_k127_158023_1 Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 302.0
CMS2_k127_158023_2 Hexapeptide repeat of succinyl-transferase K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 294.0
CMS2_k127_158023_3 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001089 246.0
CMS2_k127_1583486_0 Heat shock 70 kDa protein K04043 - - 7.668e-302 936.0
CMS2_k127_1583486_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 535.0
CMS2_k127_1583486_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 340.0
CMS2_k127_1583486_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 326.0
CMS2_k127_1583486_4 Integral membrane protein (DUF2244) - - - 0.0000000003376 68.0
CMS2_k127_1583486_5 - - - - 0.00000005989 60.0
CMS2_k127_1583486_6 Etoposide-induced protein 2.4 (EI24) K06203 - - 0.0000008214 53.0
CMS2_k127_1623883_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 456.0
CMS2_k127_1623883_1 COG2518 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000005406 206.0
CMS2_k127_1623883_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000003349 192.0
CMS2_k127_1623883_3 - - - - 0.00000000000000000000001987 105.0
CMS2_k127_1623883_4 Putative zinc- or iron-chelating domain - - - 0.00000000000000000685 94.0
CMS2_k127_1623883_5 transferase activity, transferring glycosyl groups - - - 0.00001983 49.0
CMS2_k127_1628575_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.988e-203 641.0
CMS2_k127_1628575_1 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 310.0
CMS2_k127_1628575_2 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 299.0
CMS2_k127_1628575_3 - - - - 0.000000000000000000000000002006 117.0
CMS2_k127_1632383_0 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 355.0
CMS2_k127_1632383_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000002348 235.0
CMS2_k127_1632383_2 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000008236 190.0
CMS2_k127_1632383_3 PAS domain - - - 0.00000000000000000000000000000000000008247 149.0
CMS2_k127_1688922_0 COG0618 Exopolyphosphatase-related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 413.0
CMS2_k127_1688922_1 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 391.0
CMS2_k127_1688922_2 Nucleoside 2-deoxyribosyltransferase YtoQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000002383 245.0
CMS2_k127_1688922_3 COG0784 FOG CheY-like receiver K03413 - - 0.000000000000000000000000000000000000000000000000000000000001608 210.0
CMS2_k127_1688922_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.000000000000000000000000000000000000000000006262 164.0
CMS2_k127_1688922_5 GcrA cell cycle regulator K13583 - - 0.00000000000000000000000000000000001344 141.0
CMS2_k127_1710255_0 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 385.0
CMS2_k127_1710255_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005217 262.0
CMS2_k127_1710255_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000188 241.0
CMS2_k127_1710255_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000007402 156.0
CMS2_k127_1711135_0 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000005391 236.0
CMS2_k127_1726284_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009995 256.0
CMS2_k127_1726284_1 STAS domain K03321 - - 0.000000000000000000000000000000000000000000000000000003914 210.0
CMS2_k127_1730372_0 COG2202 FOG PAS PAC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 449.0
CMS2_k127_1730372_1 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 357.0
CMS2_k127_1730372_3 COG0784 FOG CheY-like receiver - - - 0.0007178 45.0
CMS2_k127_1733367_0 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 580.0
CMS2_k127_1733367_1 repeat protein - - - 0.0000000000000000000000000000000000000003077 155.0
CMS2_k127_1733367_2 Belongs to the peptidase S1C family - - - 0.0007973 53.0
CMS2_k127_1737497_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 548.0
CMS2_k127_1737497_1 Uncharacterised protein family (UPF0262) - - - 0.0000000000000000000000000000000000000000000000000000000000003327 214.0
CMS2_k127_1737497_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03741 - 1.20.4.1,3.1.3.48 0.0000000000000000000000000001181 117.0
CMS2_k127_1778378_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 7.43e-261 812.0
CMS2_k127_1778378_1 NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 0.000000389 53.0
CMS2_k127_1792673_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 298.0
CMS2_k127_1792673_1 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000004673 183.0
CMS2_k127_1792673_2 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000005595 135.0
CMS2_k127_1796077_0 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 384.0
CMS2_k127_1796077_1 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 310.0
CMS2_k127_1796077_2 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 309.0
CMS2_k127_1796810_0 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 335.0
CMS2_k127_1796810_1 AMP binding K09118,K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 293.0
CMS2_k127_1796810_2 COG0471 Di- and tricarboxylate transporters K03319,K09477,K11106,K14445 - - 0.00000000000000000000000000002381 117.0
CMS2_k127_1819293_0 Homospermidine synthase K00808 - 2.5.1.44 3.33e-280 865.0
CMS2_k127_1819293_1 PAS fold K07716 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 421.0
CMS2_k127_1821378_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 9.14e-219 688.0
CMS2_k127_1821378_1 (LPS) heptosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 344.0
CMS2_k127_1821378_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 324.0
CMS2_k127_1821378_3 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 293.0
CMS2_k127_1821378_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000004223 147.0
CMS2_k127_1821378_5 Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.00000000000000000000004162 105.0
CMS2_k127_1821378_6 glycosyl transferase group 1 - - - 0.0000000000000000000007888 96.0
CMS2_k127_1826954_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.147e-262 817.0
CMS2_k127_184667_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 4.684e-246 778.0
CMS2_k127_184667_1 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488,K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000000003806 230.0
CMS2_k127_184667_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000001301 216.0
CMS2_k127_184667_3 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.000000000000000000000000000000000000000000000000000001165 199.0
CMS2_k127_184667_4 Ferredoxin K04755 - - 0.0000000000000000000000000000000000000000000000000009362 185.0
CMS2_k127_184667_5 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000000000000005555 179.0
CMS2_k127_184667_6 Protein conserved in bacteria - - - 0.000000000000000000000000000000004056 131.0
CMS2_k127_1890516_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 1.294e-205 659.0
CMS2_k127_1890516_1 COG4166 ABC-type oligopeptide transport system, periplasmic component K13893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 567.0
CMS2_k127_1890516_2 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000957 364.0
CMS2_k127_1890516_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 351.0
CMS2_k127_1890516_4 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 297.0
CMS2_k127_1890516_5 Cytochrome c K08738 - - 0.0000000000000000000000000003777 120.0
CMS2_k127_1890516_6 - - - - 0.000007319 55.0
CMS2_k127_189189_0 MltA specific insert domain K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 395.0
CMS2_k127_189189_1 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 331.0
CMS2_k127_189189_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000004776 199.0
CMS2_k127_1932868_0 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 465.0
CMS2_k127_1932868_1 Ribosomal L28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000003322 136.0
CMS2_k127_1932868_2 - - - - 0.0000000000000000003396 95.0
CMS2_k127_1934680_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 542.0
CMS2_k127_1934680_1 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 428.0
CMS2_k127_1934680_2 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 344.0
CMS2_k127_1934680_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000002806 135.0
CMS2_k127_194916_0 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 503.0
CMS2_k127_194916_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
CMS2_k127_194916_2 Methyltransferase small domain K15460 - 2.1.1.223 0.0000000000000005378 79.0
CMS2_k127_194916_3 - - - - 0.0000000000113 68.0
CMS2_k127_1968553_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.231e-242 766.0
CMS2_k127_1968553_1 Histidine kinase K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 490.0
CMS2_k127_1968553_10 Putative bacterial sensory transduction regulator - - - 0.000000000000000000000000000000000000000000000000000000000669 206.0
CMS2_k127_1968553_11 transcriptional - - - 0.000000000000000000000000000000000000000000000000002018 186.0
CMS2_k127_1968553_12 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000005628 180.0
CMS2_k127_1968553_13 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000007329 154.0
CMS2_k127_1968553_14 Putative tRNA binding domain K06878 GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000001544 115.0
CMS2_k127_1968553_15 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000000000001437 105.0
CMS2_k127_1968553_16 Membrane fusogenic activity K09806 - - 0.000000000000000000113 91.0
CMS2_k127_1968553_17 COG0073 EMAP domain K06878 GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0017101,GO:0017102,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000001367 80.0
CMS2_k127_1968553_2 COG0303 Molybdopterin biosynthesis enzyme K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 482.0
CMS2_k127_1968553_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 424.0
CMS2_k127_1968553_4 3-beta hydroxysteroid dehydrogenase/isomerase family K01784,K03274 - 5.1.3.2,5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 361.0
CMS2_k127_1968553_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 351.0
CMS2_k127_1968553_6 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 293.0
CMS2_k127_1968553_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001894 274.0
CMS2_k127_1968553_8 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000002565 228.0
CMS2_k127_1968553_9 COG0314 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000002912 222.0
CMS2_k127_199608_0 COG0004 Ammonia permease K03320 - - 3.492e-203 638.0
CMS2_k127_199608_1 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 502.0
CMS2_k127_1999794_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 1.745e-204 647.0
CMS2_k127_1999794_1 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000001517 58.0
CMS2_k127_2011421_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 526.0
CMS2_k127_2011421_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000309 234.0
CMS2_k127_2011421_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000001327 159.0
CMS2_k127_2011421_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000002831 110.0
CMS2_k127_2012370_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 8.746e-295 912.0
CMS2_k127_2012370_1 Stimulus-sensing domain K14980 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 391.0
CMS2_k127_2012370_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K14981 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 353.0
CMS2_k127_2012370_3 Protein of unknown function (DUF1538) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 333.0
CMS2_k127_2012370_4 Protein of unknown function (DUF1538) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 322.0
CMS2_k127_2012370_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000007055 160.0
CMS2_k127_2012370_6 Belongs to the P(II) protein family - - - 0.0000000000000000000000000000000226 130.0
CMS2_k127_2012370_7 coenzyme F420 binding K07226 - - 0.000000000000000000000000000004513 126.0
CMS2_k127_201364_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 9.098e-309 971.0
CMS2_k127_201364_1 Dihaem cytochrome c - - - 0.0000000000000000000000003393 116.0
CMS2_k127_2049938_0 TonB dependent receptor - - - 1.842e-246 780.0
CMS2_k127_2049938_1 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 384.0
CMS2_k127_2049938_2 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000002181 134.0
CMS2_k127_2057780_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001463 260.0
CMS2_k127_2057780_1 periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000000000000002318 171.0
CMS2_k127_2057780_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000001032 170.0
CMS2_k127_2057780_3 Belongs to the UPF0102 family K07460 - - 0.0002543 44.0
CMS2_k127_2058251_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 2.904e-250 788.0
CMS2_k127_2058251_1 TIGRFAM methylmalonic acid semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 6.061e-231 724.0
CMS2_k127_2058251_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 486.0
CMS2_k127_2058251_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 470.0
CMS2_k127_2058251_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000000000000000718 153.0
CMS2_k127_2058251_5 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000001071 136.0
CMS2_k127_2058251_6 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000001032 106.0
CMS2_k127_2058251_7 receptor - - - 0.0000002636 56.0
CMS2_k127_2076351_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 8.74e-213 672.0
CMS2_k127_2076351_1 membrane protein (DUF2078) K08982 - - 0.0000001182 58.0
CMS2_k127_2083779_0 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 450.0
CMS2_k127_2083779_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 400.0
CMS2_k127_2083779_2 COG1177 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 394.0
CMS2_k127_2083779_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000009939 198.0
CMS2_k127_2083779_4 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.00000000000000000000000000000000000000000000000001537 188.0
CMS2_k127_2083779_5 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000008609 121.0
CMS2_k127_2098943_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 485.0
CMS2_k127_2098943_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 465.0
CMS2_k127_2098943_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 436.0
CMS2_k127_2098943_3 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 397.0
CMS2_k127_2098943_4 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 320.0
CMS2_k127_2098943_5 COG3637 Opacity protein and related surface antigens - - - 0.000000000000000000000000000000000000000000000000000000000000000006712 239.0
CMS2_k127_2098943_6 COG3143 Chemotaxis protein K03414 - - 0.00000000000000000000000000000000000000000000658 172.0
CMS2_k127_2098943_7 Stringent starvation protein B K09985 - - 0.0000000000000000000000000000000000000006524 154.0
CMS2_k127_2098943_8 - - - - 0.000000000000004538 82.0
CMS2_k127_2098943_9 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000001646 58.0
CMS2_k127_2109003_0 Pilus formation protein N terminal region K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 299.0
CMS2_k127_2109003_1 TIGRFAM pilus (Caulobacter type) biogenesis lipoprotein CpaD K02281 - - 0.00000000000101 76.0
CMS2_k127_2109003_2 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.000125 50.0
CMS2_k127_2109397_0 Belongs to the peptidase S16 family - - - 7.503e-282 892.0
CMS2_k127_2109397_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 579.0
CMS2_k127_2109397_2 flagellar motor component K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005563 275.0
CMS2_k127_2109397_3 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000001443 211.0
CMS2_k127_2109397_4 Zincin-like metallopeptidase - - - 0.00000000000000000000000000000000000000000002007 178.0
CMS2_k127_2109397_5 EamA-like transporter family - - - 0.000000000000000000001333 99.0
CMS2_k127_2129503_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15785 - 2.6.1.76 1.553e-233 730.0
CMS2_k127_2129503_1 Aldehyde dehydrogenase family K15786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 359.0
CMS2_k127_2129503_2 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000005343 267.0
CMS2_k127_2129503_3 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000003349 198.0
CMS2_k127_2129503_4 repeat protein - - - 0.0000005456 59.0
CMS2_k127_2129503_5 EamA-like transporter family - - - 0.000009757 57.0
CMS2_k127_2134311_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 460.0
CMS2_k127_2134311_1 Fatty acid synthesis protein K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 444.0
CMS2_k127_2134311_2 bacterial (prokaryotic) histone like domain K04764 - - 0.000000000000000000000000000000000000000000006124 165.0
CMS2_k127_21412_0 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 374.0
CMS2_k127_21412_1 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000002609 189.0
CMS2_k127_21412_2 - - - - 0.00000000000000000002752 92.0
CMS2_k127_2186281_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 383.0
CMS2_k127_2186281_1 EVE domain - - - 0.00000000000000000000000000000000000000000000000001318 187.0
CMS2_k127_2186281_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000005782 147.0
CMS2_k127_2186281_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000004398 135.0
CMS2_k127_2186281_4 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000000000000000005313 122.0
CMS2_k127_2186281_5 Protein conserved in bacteria K09780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000342 108.0
CMS2_k127_2198672_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004621 452.0
CMS2_k127_2198672_1 Cold shock K03704 - - 0.00000000000000000000000001519 109.0
CMS2_k127_2198672_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000003256 63.0
CMS2_k127_2199739_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 409.0
CMS2_k127_2199739_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 354.0
CMS2_k127_2201129_0 Acyl transferase domain K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 401.0
CMS2_k127_2201129_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000006185 234.0
CMS2_k127_2203840_0 Cytochrome c bacterial - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 320.0
CMS2_k127_2203840_1 cell redox homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000001397 228.0
CMS2_k127_2203840_2 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000007828 180.0
CMS2_k127_2203840_3 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000002267 150.0
CMS2_k127_2203840_4 Iron-sulphur cluster biosynthesis K15724 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0010467,GO:0015980,GO:0016043,GO:0016226,GO:0019538,GO:0022607,GO:0031163,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046872,GO:0046914,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055114,GO:0071704,GO:0071840,GO:1901564 - 0.000000000000000000000000000000005319 131.0
CMS2_k127_2204397_0 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 412.0
CMS2_k127_2204397_1 HIT domain - - - 0.00000000000000000000000000000000000009965 145.0
CMS2_k127_2204397_2 Protein of unknown function (DUF1491) - - - 0.00000000000000000000379 96.0
CMS2_k127_2227171_0 transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000869 249.0
CMS2_k127_2227171_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000002145 169.0
CMS2_k127_2227171_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008378,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000002188 162.0
CMS2_k127_2240217_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 2.021e-203 643.0
CMS2_k127_2240217_1 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000005077 141.0
CMS2_k127_2240217_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000004887 113.0
CMS2_k127_2240217_3 Rhodanese Homology Domain - - - 0.0000000000000000000000003793 111.0
CMS2_k127_2240217_4 oxygen carrier activity K07216 - - 0.000000000004607 72.0
CMS2_k127_2247822_0 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 580.0
CMS2_k127_2247822_1 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000001722 195.0
CMS2_k127_226459_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002894 266.0
CMS2_k127_226459_1 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000001541 177.0
CMS2_k127_226459_2 long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000176 121.0
CMS2_k127_2272206_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 8.447e-211 661.0
CMS2_k127_2272206_1 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 320.0
CMS2_k127_2272206_10 Bacterial regulatory proteins, tetR family K16137 - - 0.00000000000000000000000000000007239 135.0
CMS2_k127_2272206_2 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002526 276.0
CMS2_k127_2272206_3 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K20945 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000001432 208.0
CMS2_k127_2272206_4 subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000003785 200.0
CMS2_k127_2272206_5 DSBA-like thioredoxin domain K07396 - - 0.00000000000000000000000000000000000000000000000001003 188.0
CMS2_k127_2272206_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000006483 177.0
CMS2_k127_2272206_7 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000008927 177.0
CMS2_k127_2272206_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000007367 154.0
CMS2_k127_2272206_9 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K03796 - - 0.00000000000000000000000000000002203 137.0
CMS2_k127_2288634_0 Pyridine nucleotide-disulphide oxidoreductase K05297 - 1.18.1.1 0.00000000000000000000000000000000000000000000000000001244 191.0
CMS2_k127_2288634_1 Formate dehydrogenase subunit alpha - - - 0.000000000000000000000000000000000000008217 147.0
CMS2_k127_2288634_2 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000000000003291 130.0
CMS2_k127_2288634_3 Mut7-C ubiquitin - - - 0.00000000000000000000005921 101.0
CMS2_k127_2294330_0 Surface antigen K07277 - - 9.841e-267 842.0
CMS2_k127_2294330_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 495.0
CMS2_k127_2294330_10 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000004633 223.0
CMS2_k127_2294330_11 Protein conserved in bacteria K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000002432 224.0
CMS2_k127_2294330_12 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000003101 196.0
CMS2_k127_2294330_13 Autoinducer synthase K13060,K13061 - 2.3.1.184 0.00000000000000000000000000000000000000000000000002715 185.0
CMS2_k127_2294330_14 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000002017 177.0
CMS2_k127_2294330_15 Amino acid kinase family K09903 - 2.7.4.22 0.000000000000000000000000000000002139 138.0
CMS2_k127_2294330_16 COG2825 Outer membrane protein - - - 0.000000000000000001503 93.0
CMS2_k127_2294330_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 410.0
CMS2_k127_2294330_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 389.0
CMS2_k127_2294330_4 Udp N-acetylglucosamine O-acyltransferase; Domain 2 K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 374.0
CMS2_k127_2294330_5 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 365.0
CMS2_k127_2294330_6 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 316.0
CMS2_k127_2294330_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 315.0
CMS2_k127_2294330_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005369 256.0
CMS2_k127_2294330_9 Amino acid kinase family K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000001193 241.0
CMS2_k127_2296305_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 473.0
CMS2_k127_2296305_1 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 449.0
CMS2_k127_2296305_2 pdz dhr glgf - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 352.0
CMS2_k127_2296305_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 316.0
CMS2_k127_2296305_4 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005089 261.0
CMS2_k127_2296305_5 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008246 269.0
CMS2_k127_2296305_6 COG0784 FOG CheY-like receiver K11443 - - 0.00000000000000000000000000000000000000000000000000000000000183 211.0
CMS2_k127_2296305_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000001615 98.0
CMS2_k127_2296305_8 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000007478 58.0
CMS2_k127_2304948_0 COG1760 L-serine deaminase K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 548.0
CMS2_k127_2304948_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 380.0
CMS2_k127_2304948_2 COG0512 Anthranilate para-aminobenzoate synthases component II K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 294.0
CMS2_k127_2304948_3 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001798 247.0
CMS2_k127_2319795_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 398.0
CMS2_k127_2319795_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 362.0
CMS2_k127_2319795_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 328.0
CMS2_k127_2319795_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 309.0
CMS2_k127_2319795_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 281.0
CMS2_k127_2319795_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000001535 201.0
CMS2_k127_2319795_6 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000006907 183.0
CMS2_k127_2319795_7 Preprotein translocase subunit SecB K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000006812 165.0
CMS2_k127_233977_0 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004793 268.0
CMS2_k127_233977_1 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005852 253.0
CMS2_k127_233977_2 bond formation protein, DsbB - - - 0.0000000000000000000000000000003237 128.0
CMS2_k127_233977_3 - - - - 0.0007461 50.0
CMS2_k127_2345076_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 444.0
CMS2_k127_2345076_1 BioY family K03523 - - 0.000000000000000000000000000000000000000000000000000000000000007593 222.0
CMS2_k127_2345076_2 - - - - 0.00000000000000000000006756 106.0
CMS2_k127_2352770_0 short chain dehydrogenase reductase family K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000005172 218.0
CMS2_k127_2352770_1 KR domain - - - 0.0000000000003424 70.0
CMS2_k127_2352770_2 spore germination - - - 0.00000000001315 75.0
CMS2_k127_2369871_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001075 271.0
CMS2_k127_2369871_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000003394 227.0
CMS2_k127_2369871_2 Domain of unknown function (DUF1732) - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000001478 226.0
CMS2_k127_2375045_0 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 374.0
CMS2_k127_2375045_1 Belongs to the peptidase S1B family K01183,K03791,K08651,K14645 - 3.2.1.14,3.4.21.66 0.000000000000000000000000000000000000000000000000000000000009451 225.0
CMS2_k127_2375045_2 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000001127 181.0
CMS2_k127_2385110_0 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 363.0
CMS2_k127_2385110_1 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000001431 224.0
CMS2_k127_2388275_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 2.656e-296 923.0
CMS2_k127_2388275_1 AAA domain, putative AbiEii toxin, Type IV TA system K02028,K10021 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 345.0
CMS2_k127_2388275_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 295.0
CMS2_k127_2388275_3 Ligated ion channel L-glutamate- and glycine-binding site K02030 - - 0.00000000000000000000000000000000000000000000000000526 184.0
CMS2_k127_2436424_0 Penicillin-binding protein 5, C-terminal domain K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 393.0
CMS2_k127_2436424_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 294.0
CMS2_k127_2436424_2 Murein transglycosylase K00786,K08305 - - 0.000000000000000000001443 96.0
CMS2_k127_2458129_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005588 274.0
CMS2_k127_2458129_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001712 258.0
CMS2_k127_2458129_2 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000889 192.0
CMS2_k127_2458129_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000006039 104.0
CMS2_k127_2458129_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0003674,GO:0005215 - 0.000000000000000428 80.0
CMS2_k127_2458129_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000006878 70.0
CMS2_k127_2469353_0 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000007208 213.0
CMS2_k127_2469353_1 protein involved in response to NO K07234 - - 0.0000000000000000000000000000000000000000000000000000000006228 211.0
CMS2_k127_2476621_0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001074 215.0
CMS2_k127_2476621_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000006737 202.0
CMS2_k127_2476621_2 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000006127 164.0
CMS2_k127_2476621_3 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000006134 162.0
CMS2_k127_2476621_4 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000002249 84.0
CMS2_k127_2489316_0 malic enzyme K00029 - 1.1.1.40 0.0 1049.0
CMS2_k127_2489316_1 This protein is involved in the repair of mismatches in DNA K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 466.0
CMS2_k127_2489316_2 Phosphate K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 346.0
CMS2_k127_2489316_3 Periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000000000000000002074 178.0
CMS2_k127_2519927_0 Bacterial signalling protein N terminal repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 349.0
CMS2_k127_2519927_1 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 293.0
CMS2_k127_2531858_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 427.0
CMS2_k127_2531858_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 304.0
CMS2_k127_2541815_0 Na phosphate symporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 418.0
CMS2_k127_2541815_1 Cytochrome c-type protein K02569,K03532 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002825 251.0
CMS2_k127_2541815_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002828 248.0
CMS2_k127_2541815_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000019 194.0
CMS2_k127_2541815_4 HPP family - - - 0.0000000000000000000000000000000000000000000000000002144 191.0
CMS2_k127_2541815_5 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000001109 137.0
CMS2_k127_2541815_6 Cytochrome c K08738 - - 0.0000000000000000000002033 100.0
CMS2_k127_2541815_7 PFAM Diacylglycerol kinase, catalytic domain - - - 0.0000000000000000000003083 100.0
CMS2_k127_2541815_8 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000001293 89.0
CMS2_k127_2541815_9 tetR family - - - 0.00000000004302 63.0
CMS2_k127_2553963_0 4Fe-4S dicluster domain - - - 6.54e-203 649.0
CMS2_k127_2553963_1 Cysteine-rich domain K21834 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 318.0
CMS2_k127_2553963_2 Mo-molybdopterin cofactor metabolic process K02379,K03750,K03752,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000315 213.0
CMS2_k127_257623_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 381.0
CMS2_k127_2586356_0 helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000006207 256.0
CMS2_k127_2586356_1 - - - - 0.00000004671 61.0
CMS2_k127_2602837_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 396.0
CMS2_k127_2602837_1 protein conserved in bacteria K09987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001421 263.0
CMS2_k127_2602837_2 Protein of unknown function (DUF1192) - - - 0.000000000001807 68.0
CMS2_k127_2603867_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 541.0
CMS2_k127_2603867_1 succinylglutamate desuccinylase K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 430.0
CMS2_k127_2603867_2 Prokaryotic glutathione synthetase, ATP-grasp domain K05844,K14940 - 6.3.2.32 0.000000000002069 66.0
CMS2_k127_2620387_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005473 288.0
CMS2_k127_2620387_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000001158 205.0
CMS2_k127_2620387_2 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000004484 164.0
CMS2_k127_2620387_3 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000002555 130.0
CMS2_k127_2620387_4 - - - - 0.0000000000000003344 87.0
CMS2_k127_2634797_0 D-isomer specific 2-hydroxyacid dehydrogenase K03778,K18916 - 1.1.1.28,1.20.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 419.0
CMS2_k127_2634797_1 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 285.0
CMS2_k127_265619_0 COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases K02230 - 6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 400.0
CMS2_k127_265619_1 Sugar (and other) transporter K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 359.0
CMS2_k127_265619_2 COG0744 Membrane carboxypeptidase (penicillin-binding protein) K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000001034 231.0
CMS2_k127_2681395_0 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 396.0
CMS2_k127_2681395_1 - - - - 0.000000000000000000000006108 106.0
CMS2_k127_2761504_0 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005805 281.0
CMS2_k127_2761504_1 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000006214 159.0
CMS2_k127_2761504_2 diguanylate cyclase K11444 - 2.7.7.65 0.0000000000000000000000000000000000009717 151.0
CMS2_k127_2765680_0 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 539.0
CMS2_k127_2765680_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 504.0
CMS2_k127_2765680_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000003815 184.0
CMS2_k127_2777728_0 Function of homologous gene experimentally demonstrated in an other organism K03407 - 2.7.13.3 6.524e-271 864.0
CMS2_k127_2777728_1 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 1.094e-219 693.0
CMS2_k127_2777728_10 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) - - - 0.00000000000000000000002323 105.0
CMS2_k127_2777728_11 - - - - 0.00000000000000007723 85.0
CMS2_k127_2777728_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit K00122,K00124,K00335 - 1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 510.0
CMS2_k127_2777728_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 416.0
CMS2_k127_2777728_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K13584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 397.0
CMS2_k127_2777728_5 Formate dehydrogenase subunit alpha - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 372.0
CMS2_k127_2777728_6 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 311.0
CMS2_k127_2777728_7 COG0784 FOG CheY-like receiver K03413 - - 0.00000000000000000000000000000000000000000000000000000000000001162 216.0
CMS2_k127_2777728_8 - - - - 0.0000000000000000000000000000000005387 140.0
CMS2_k127_2777728_9 Histidine phosphotransferase C-terminal domain K13588 - - 0.000000000000000000000000002867 125.0
CMS2_k127_2782863_0 ABC-type Fe3 transport system permease component K02011 - - 1.071e-230 727.0
CMS2_k127_2782863_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 520.0
CMS2_k127_2782863_10 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000000000000000000007006 159.0
CMS2_k127_2782863_11 Recombinase zinc beta ribbon domain - - - 0.00002177 48.0
CMS2_k127_2782863_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 456.0
CMS2_k127_2782863_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 322.0
CMS2_k127_2782863_4 Nitroreductase family K04719 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016491,GO:0016705,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 292.0
CMS2_k127_2782863_5 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003872 283.0
CMS2_k127_2782863_6 Transcriptional regulator, DeoR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001686 274.0
CMS2_k127_2782863_7 PPIC-type PPIASE domain K01802,K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000002663 218.0
CMS2_k127_2782863_8 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000005307 200.0
CMS2_k127_2782863_9 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000001142 200.0
CMS2_k127_2786888_0 asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 575.0
CMS2_k127_2786888_1 Putative zinc binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 488.0
CMS2_k127_2786888_2 CDP-glucose 4,6-dehydratase K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 366.0
CMS2_k127_2786888_3 RmlD substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004134 268.0
CMS2_k127_2786888_4 Macrocin-O-methyltransferase (TylF) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004325 250.0
CMS2_k127_2786888_5 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001373 244.0
CMS2_k127_2786888_6 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000001257 208.0
CMS2_k127_2786888_7 Protein of unknown function (DUF616) - - - 0.00000000000000000000000000000000000000000001503 170.0
CMS2_k127_2786888_9 Nucleotidyl transferase K00978,K15669 - 2.7.7.33,2.7.7.71 0.00000000000000001172 82.0
CMS2_k127_2789936_0 DNA helicase K03657 - 3.6.4.12 1.446e-309 965.0
CMS2_k127_2789936_1 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 511.0
CMS2_k127_2789936_10 Methyltransferase domain - - - 0.0000000000000000000000000000001486 134.0
CMS2_k127_2789936_11 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000000000006319 106.0
CMS2_k127_2789936_12 - - - - 0.000004834 56.0
CMS2_k127_2789936_13 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0001844 51.0
CMS2_k127_2789936_2 COG3264 Small-conductance mechanosensitive channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 385.0
CMS2_k127_2789936_3 ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003304 254.0
CMS2_k127_2789936_4 Voltage gated chloride channel K03281 - - 0.000000000000000000000000000000000000000000000000000000000000000000002172 244.0
CMS2_k127_2789936_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001383 237.0
CMS2_k127_2789936_6 AzlC protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002585 229.0
CMS2_k127_2789936_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000001043 207.0
CMS2_k127_2789936_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000005323 186.0
CMS2_k127_2789936_9 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000001641 136.0
CMS2_k127_2817076_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.897e-270 840.0
CMS2_k127_2861904_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.702e-208 654.0
CMS2_k127_2861904_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 458.0
CMS2_k127_2861904_10 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000006161 160.0
CMS2_k127_2861904_11 Lipopolysaccharide assembly protein A domain K08992 - - 0.00000001169 62.0
CMS2_k127_2861904_2 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 442.0
CMS2_k127_2861904_3 NADH flavin K09461 - 1.14.13.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 418.0
CMS2_k127_2861904_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 384.0
CMS2_k127_2861904_5 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000117 284.0
CMS2_k127_2861904_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001789 281.0
CMS2_k127_2861904_7 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001469 264.0
CMS2_k127_2861904_8 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000004459 228.0
CMS2_k127_2861904_9 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000004171 181.0
CMS2_k127_2869555_0 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 511.0
CMS2_k127_2869555_1 signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 353.0
CMS2_k127_2869555_2 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000007099 147.0
CMS2_k127_2869555_3 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000006866 98.0
CMS2_k127_2929997_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 6.672e-234 729.0
CMS2_k127_2929997_1 FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 411.0
CMS2_k127_2929997_2 glycolate oxidase iron-sulfur subunit K11473 - - 0.00000000000000002986 82.0
CMS2_k127_2931366_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 377.0
CMS2_k127_2931366_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 350.0
CMS2_k127_2931366_2 Staphylococcal nuclease homologue - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002046 259.0
CMS2_k127_2931366_3 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000000000000000000000000003084 140.0
CMS2_k127_2956016_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.6e-275 864.0
CMS2_k127_2956016_1 Bacterial DNA topoisomeraes I ATP-binding domain K03168 - 5.99.1.2 0.000005509 50.0
CMS2_k127_295685_0 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 350.0
CMS2_k127_295685_1 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 307.0
CMS2_k127_295685_2 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000000000000000000000000000000000000000000000000000000001447 218.0
CMS2_k127_295685_3 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000006664 68.0
CMS2_k127_2960303_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.199e-270 838.0
CMS2_k127_2960303_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 6.752e-252 790.0
CMS2_k127_2960303_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 369.0
CMS2_k127_2960303_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000003937 194.0
CMS2_k127_2960303_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000003245 94.0
CMS2_k127_2975145_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 3.043e-321 988.0
CMS2_k127_2975145_1 COG0659 Sulfate permease and related transporters (MFS superfamily K03321 - - 4.454e-205 644.0
CMS2_k127_2975145_10 Belongs to the urease gamma subunit family K01430,K14048 - 3.5.1.5 0.000000000000000000000000000000000000000000000003266 173.0
CMS2_k127_2975145_11 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000000000000000000000000000000000000003122 169.0
CMS2_k127_2975145_12 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.00000000000000000000000000000000000000000001043 167.0
CMS2_k127_2975145_13 Belongs to the binding-protein-dependent transport system permease family K01998,K11961 - - 0.0000000000000000000000000000000007571 130.0
CMS2_k127_2975145_14 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000000000000000001711 119.0
CMS2_k127_2975145_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 602.0
CMS2_k127_2975145_3 ABC transporter, (ATP-binding protein) K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 369.0
CMS2_k127_2975145_4 abc transporter atp-binding protein K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 358.0
CMS2_k127_2975145_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 344.0
CMS2_k127_2975145_6 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 334.0
CMS2_k127_2975145_7 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001967 285.0
CMS2_k127_2975145_8 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.000000000000000000000000000000000000000000000000000000000009825 215.0
CMS2_k127_2975145_9 Belongs to the binding-protein-dependent transport system permease family K01998,K11961 - - 0.000000000000000000000000000000000000000000000000000004607 192.0
CMS2_k127_2976151_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 491.0
CMS2_k127_2976151_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 372.0
CMS2_k127_2976151_2 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000008873 201.0
CMS2_k127_2988940_0 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 303.0
CMS2_k127_2988940_1 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000061 68.0
CMS2_k127_2988940_2 Histidine Phosphotransfer domain - - - 0.0000001687 59.0
CMS2_k127_299516_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000003268 243.0
CMS2_k127_299516_1 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000001738 231.0
CMS2_k127_299516_2 Flagellar basal body protein FlaE K02390 - - 0.0000000000000000000000000000000000000000000000000413 194.0
CMS2_k127_299516_3 Phage-associated protein - - - 0.000000000000000000000000000000000000000003819 159.0
CMS2_k127_299516_4 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000004068 120.0
CMS2_k127_3008769_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1383.0
CMS2_k127_3008769_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 300.0
CMS2_k127_3008769_2 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000001278 228.0
CMS2_k127_3008769_3 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000002422 88.0
CMS2_k127_3008769_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000002502 65.0
CMS2_k127_3060079_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 499.0
CMS2_k127_3060079_1 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 310.0
CMS2_k127_3060079_2 invasion associated locus B - - - 0.00000000000000000000000000000000000000000009336 164.0
CMS2_k127_3072898_0 PFAM Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 614.0
CMS2_k127_3072898_1 Flagella basal body rod protein K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 386.0
CMS2_k127_3072898_2 COG1840 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 391.0
CMS2_k127_3072898_3 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 354.0
CMS2_k127_3072898_4 Flagellar L-ring protein K02393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000111 283.0
CMS2_k127_3072898_5 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000344 219.0
CMS2_k127_3072898_6 SAF K02386 - - 0.00000000000000000000000000000000000000000000000000001367 201.0
CMS2_k127_3072898_7 Flagellar basal body rod FlgEFG protein C-terminal K02391,K02392 - - 0.000000000000000000000000005548 113.0
CMS2_k127_3075702_0 TOBE domain K11076 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 498.0
CMS2_k127_3075702_1 ABC-type spermidine putrescine transport system, permease component I K11075 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 412.0
CMS2_k127_3075702_2 ABC-type spermidine putrescine transport system, permease component II K11074 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000002149 199.0
CMS2_k127_3075702_3 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0019808,GO:0019810,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0051179,GO:0051234,GO:0070405,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000007468 191.0
CMS2_k127_3081988_0 5'-nucleotidase, C-terminal domain K17224 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 536.0
CMS2_k127_3081988_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 313.0
CMS2_k127_308902_0 Von willebrand factor, type a - - - 0.0 1080.0
CMS2_k127_308902_1 Belongs to the RuBisCO large chain family K01601 - 4.1.1.39 1.856e-273 844.0
CMS2_k127_308902_10 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000001091 184.0
CMS2_k127_308902_2 ABC transporter transmembrane region K06147 - - 3.634e-237 747.0
CMS2_k127_308902_3 Cupin superfamily protein K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 508.0
CMS2_k127_308902_4 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 445.0
CMS2_k127_308902_5 Transcriptional regulator K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 352.0
CMS2_k127_308902_6 HI0933-like protein K07007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 346.0
CMS2_k127_308902_7 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009591 339.0
CMS2_k127_308902_8 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 323.0
CMS2_k127_308902_9 Serine hydrolase K07002 - - 0.000000000000000000000000000000000000000000000001595 180.0
CMS2_k127_3109667_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 6.453e-211 665.0
CMS2_k127_3109667_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 2.099e-203 641.0
CMS2_k127_3109667_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 385.0
CMS2_k127_3109667_3 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 347.0
CMS2_k127_3109667_4 FtsJ-like methyltransferase K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005661 278.0
CMS2_k127_3109667_5 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000009521 247.0
CMS2_k127_3109667_6 Protein required for attachment to host cells - - - 0.000000000000000000000000000000002487 133.0
CMS2_k127_3109667_7 - - - - 0.000000000005037 70.0
CMS2_k127_3122738_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.084e-265 825.0
CMS2_k127_3122738_1 Rod shape-determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 609.0
CMS2_k127_3122738_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 509.0
CMS2_k127_3122738_3 FAD dependent oxidoreductase K15736 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 493.0
CMS2_k127_3122738_4 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit K00316 - 1.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 471.0
CMS2_k127_3122738_5 - - - - 0.000000000000007316 82.0
CMS2_k127_3148252_0 (ABC) transporter K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001895 280.0
CMS2_k127_3148252_1 (ABC) transporter K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009826 271.0
CMS2_k127_3148252_2 belongs to the bacterial solute-binding protein 3 family K02030,K09996,K10014,K10022 - - 0.00000000000000000000000000000000000000000005512 161.0
CMS2_k127_3159531_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0 1610.0
CMS2_k127_3159531_1 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000287 206.0
CMS2_k127_316514_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 527.0
CMS2_k127_316514_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 507.0
CMS2_k127_316514_2 COG4942 Membrane-bound metallopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000157 267.0
CMS2_k127_316514_3 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000001007 202.0
CMS2_k127_316514_4 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000000000006733 210.0
CMS2_k127_316514_5 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000004205 111.0
CMS2_k127_3180387_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 492.0
CMS2_k127_3180387_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 305.0
CMS2_k127_3180387_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000001502 268.0
CMS2_k127_3180387_3 Sec-independent protein translocase protein (TatC) K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003988 258.0
CMS2_k127_3180387_4 Lysin motif K06194 - - 0.000000000000000000000000000000000000000000000000000000000001412 220.0
CMS2_k127_320432_0 MacB-like periplasmic core domain K02004 - - 2.75e-227 729.0
CMS2_k127_320432_1 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 574.0
CMS2_k127_320432_2 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 374.0
CMS2_k127_320432_3 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 289.0
CMS2_k127_320432_4 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003862 250.0
CMS2_k127_320432_5 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000003501 209.0
CMS2_k127_3242786_0 Nitronate monooxygenase K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 511.0
CMS2_k127_3242786_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 421.0
CMS2_k127_3242786_2 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 297.0
CMS2_k127_325254_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1515.0
CMS2_k127_325254_1 COG0784 FOG CheY-like receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 295.0
CMS2_k127_325254_2 CHAD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005959 290.0
CMS2_k127_325254_3 RESPONSE REGULATOR receiver - - - 0.000000000000000000000000000000000007677 141.0
CMS2_k127_3259309_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 493.0
CMS2_k127_3259309_1 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 471.0
CMS2_k127_3259309_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000004928 169.0
CMS2_k127_3330121_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 416.0
CMS2_k127_3330121_1 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.000000000000000004559 90.0
CMS2_k127_3350819_0 ABC transporter transmembrane region K12541 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 413.0
CMS2_k127_3350819_1 Type I secretion membrane fusion protein, HlyD K12542 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 367.0
CMS2_k127_3350819_2 Outer membrane efflux protein K12543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 323.0
CMS2_k127_3375380_0 COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase) K09883 - 6.6.1.2 3.523e-195 628.0
CMS2_k127_3375380_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 407.0
CMS2_k127_3375380_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000875 168.0
CMS2_k127_3375380_3 Protein conserved in bacteria K09796 - - 0.0000000000000000000000000000000000009318 145.0
CMS2_k127_3375380_4 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.0000000000000000000000000000000000362 135.0
CMS2_k127_3375380_5 iron ion homeostasis - - - 0.00000000000001533 76.0
CMS2_k127_3403694_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.5e-211 663.0
CMS2_k127_3403694_1 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 547.0
CMS2_k127_3403694_2 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004804 267.0
CMS2_k127_3403694_3 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.000000000000000000000000000000000000000000000000000000001496 206.0
CMS2_k127_3403694_4 YbaK prolyl-tRNA synthetase associated - - - 0.0000000000000000000000000000000000000000004095 166.0
CMS2_k127_3464588_0 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 358.0
CMS2_k127_3464588_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 344.0
CMS2_k127_3464588_10 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000256 107.0
CMS2_k127_3464588_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 325.0
CMS2_k127_3464588_3 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005187 260.0
CMS2_k127_3464588_4 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000003325 191.0
CMS2_k127_3464588_5 Putative heavy-metal-binding - - - 0.00000000000000000000000000000000000000002582 154.0
CMS2_k127_3464588_6 Putative heavy-metal-binding - - - 0.000000000000000000000000000000000000002862 151.0
CMS2_k127_3464588_7 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000003466 142.0
CMS2_k127_3464588_8 Sugar fermentation stimulation protein K06206 - - 0.0000000000000000000000000000000003487 132.0
CMS2_k127_3464588_9 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000001618 112.0
CMS2_k127_3464914_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 347.0
CMS2_k127_3464914_1 PFAM UMUC domain protein DNA-repair protein K02346,K03502 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 311.0
CMS2_k127_3464914_2 Peptidase S24-like K03503 - - 0.0000000000000000000000000000000000000253 148.0
CMS2_k127_3477022_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009923 417.0
CMS2_k127_3477022_1 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 335.0
CMS2_k127_3477022_2 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 300.0
CMS2_k127_3477022_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000000001261 222.0
CMS2_k127_3477022_4 Carbonic anhydrase K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000001178 213.0
CMS2_k127_3477022_5 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000001555 164.0
CMS2_k127_3484052_0 Peptidase U32 K08303 - - 4.844e-234 734.0
CMS2_k127_3484052_1 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000005506 141.0
CMS2_k127_3495058_0 ATPase (AAA K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 412.0
CMS2_k127_3495058_1 Preprotein translocase subunit YajC K03210 - - 0.00000000000000000000000000000000000000403 150.0
CMS2_k127_3495058_2 Protein export membrane protein K03072 - - 0.000000000000000000000000000003235 121.0
CMS2_k127_3495058_3 Cytochrome c K08738 - - 0.0000000000000001071 85.0
CMS2_k127_3496344_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.126e-240 761.0
CMS2_k127_3504674_0 Cytochrome c bacterial - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 355.0
CMS2_k127_3504674_1 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004439 274.0
CMS2_k127_3504674_2 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000001568 192.0
CMS2_k127_3514766_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 503.0
CMS2_k127_3514766_1 SecD/SecF GG Motif K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 378.0
CMS2_k127_3514766_2 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000005537 119.0
CMS2_k127_3514766_3 YsiA-like protein, C-terminal region - - - 0.0000000000000000000003547 102.0
CMS2_k127_3536466_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1206.0
CMS2_k127_3536466_1 Belongs to the ABC transporter superfamily K02031,K02032,K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 9.545e-217 685.0
CMS2_k127_3536466_2 Binding-protein-dependent transport system inner membrane component K13894 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0022857,GO:0035672,GO:0042221,GO:0042493,GO:0042884,GO:0042886,GO:0042891,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 567.0
CMS2_k127_3536466_3 transport system, permease component K13895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 525.0
CMS2_k127_3536466_4 Bacitracin resistance protein BacA K06153 GO:0008150,GO:0042221,GO:0046677,GO:0050896 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 340.0
CMS2_k127_3536466_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 300.0
CMS2_k127_3536466_6 COG4166 ABC-type oligopeptide transport system, periplasmic component K13893 - - 0.00000000000000000000000000000000000000000000000000001045 192.0
CMS2_k127_3553618_0 protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 460.0
CMS2_k127_3553618_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 321.0
CMS2_k127_3553618_2 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.000000000000000000000000000000000000000000000000000000000000000000003674 248.0
CMS2_k127_3553618_3 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000009009 222.0
CMS2_k127_3553618_4 TfoX N-terminal domain K07343 - - 0.0000000000000000000000005315 109.0
CMS2_k127_3553618_5 Ribbon-helix-helix domain - - - 0.000000000000000001933 87.0
CMS2_k127_3559392_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.377e-213 672.0
CMS2_k127_3559392_1 COG0768 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 606.0
CMS2_k127_3559392_10 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 406.0
CMS2_k127_3559392_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 407.0
CMS2_k127_3559392_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 411.0
CMS2_k127_3559392_13 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 352.0
CMS2_k127_3559392_14 Cell division protein FtsQ K03589 - - 0.0000000000000000000000000000000000000000000000000000000006149 213.0
CMS2_k127_3559392_15 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000009824 125.0
CMS2_k127_3559392_16 periplasmic protein - - - 0.000000000000002702 79.0
CMS2_k127_3559392_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 551.0
CMS2_k127_3559392_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000732 539.0
CMS2_k127_3559392_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 533.0
CMS2_k127_3559392_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 476.0
CMS2_k127_3559392_6 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 470.0
CMS2_k127_3559392_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 469.0
CMS2_k127_3559392_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 458.0
CMS2_k127_3559392_9 D-ala D-ala ligase N-terminus K00075,K01921 - 1.3.1.98,6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 427.0
CMS2_k127_3583052_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 392.0
CMS2_k127_3583052_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 340.0
CMS2_k127_3583052_2 Part of a sulfur-relay system K11179 - - 0.00000000000000000000000000000000006624 136.0
CMS2_k127_3583052_3 COG0835 Chemotaxis signal transduction protein K03408 - - 0.000000000000000000000000000000001826 135.0
CMS2_k127_3583052_4 - - - - 0.00000000000000000000000000000003709 134.0
CMS2_k127_3583052_5 DinB family - - - 0.000000000001598 69.0
CMS2_k127_3584689_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 293.0
CMS2_k127_3584689_1 Acetyltransferase (GNAT) family K03824 - - 0.000000000000000000000000000000000002966 146.0
CMS2_k127_3584689_2 COG0303 Molybdopterin biosynthesis enzyme K03750 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0042802,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.0000000000000000009324 87.0
CMS2_k127_3591275_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.1e-234 733.0
CMS2_k127_3591275_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 443.0
CMS2_k127_3591275_2 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006838 397.0
CMS2_k127_3591275_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002011 256.0
CMS2_k127_3591275_4 Uncharacterised protein family (UPF0093) K08973 - - 0.00000000000000000000000000000000000000000000000000000000145 203.0
CMS2_k127_3591275_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000001593 158.0
CMS2_k127_364468_0 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000008946 226.0
CMS2_k127_364468_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000001134 225.0
CMS2_k127_364468_2 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000000000000006022 210.0
CMS2_k127_3660635_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 3.191e-316 977.0
CMS2_k127_3660635_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 461.0
CMS2_k127_3660635_2 Succinate dehydrogenase Fumarate reductase K00241 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000002829 146.0
CMS2_k127_3660635_3 Succinate dehydrogenase, hydrophobic anchor subunit K00242 - - 0.00000000000000000000000000000004195 129.0
CMS2_k127_3660635_4 AFG1-like ATPase K06916 - - 0.00000000000000000000000000000006349 127.0
CMS2_k127_3671831_0 NAD-specific glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1463.0
CMS2_k127_3671831_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1096.0
CMS2_k127_3671831_10 Protein of unknown function (DUF1674) - - - 0.0000001369 60.0
CMS2_k127_3671831_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 5.413e-237 745.0
CMS2_k127_3671831_3 Polysaccharide biosynthesis protein K13013 - - 5.269e-219 697.0
CMS2_k127_3671831_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 463.0
CMS2_k127_3671831_5 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 418.0
CMS2_k127_3671831_6 ABC transporter K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 302.0
CMS2_k127_3671831_7 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001574 274.0
CMS2_k127_3671831_8 transmembrane transport K09696 - - 0.00000000000000000000000000000000000000000002125 177.0
CMS2_k127_3671831_9 cheY-homologous receiver domain - - - 0.00000000000000000001579 95.0
CMS2_k127_3675243_0 Ammonium Transporter Family K03320 - - 3.179e-199 628.0
CMS2_k127_3675243_1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 457.0
CMS2_k127_3675243_2 Thioredoxin K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003544 269.0
CMS2_k127_3675243_3 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000005409 187.0
CMS2_k127_3675243_4 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000000000000000000002105 186.0
CMS2_k127_3675243_5 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000004505 180.0
CMS2_k127_3675243_6 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000003612 170.0
CMS2_k127_3675243_7 Belongs to the UPF0434 family K09791 - - 0.0000000000000000001234 91.0
CMS2_k127_3677341_0 AcrB/AcrD/AcrF family - - - 0.0 1437.0
CMS2_k127_3677341_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 599.0
CMS2_k127_3677341_2 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 471.0
CMS2_k127_3677341_3 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000576 228.0
CMS2_k127_3683817_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 345.0
CMS2_k127_3683817_1 COG0593 ATPase involved in DNA replication initiation - - - 0.00000000000000000000000000000000000000000000000000000000000002397 222.0
CMS2_k127_3683817_2 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000004143 63.0
CMS2_k127_3700375_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.972e-289 889.0
CMS2_k127_3700375_1 ETC complex I subunit conserved region K00329 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000001428 191.0
CMS2_k127_3700375_2 Methyltransferase domain - - - 0.0000004232 51.0
CMS2_k127_3700375_3 - - - - 0.0003341 44.0
CMS2_k127_373993_0 nitrate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001102 279.0
CMS2_k127_373993_1 Prokaryotic cytochrome b561 K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000005274 244.0
CMS2_k127_3742938_0 N6-adenine-specific DNA methylase K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 533.0
CMS2_k127_3742938_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 406.0
CMS2_k127_3742938_2 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 396.0
CMS2_k127_3742938_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 378.0
CMS2_k127_3742938_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000001088 218.0
CMS2_k127_3742938_5 DREV methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000008772 216.0
CMS2_k127_3742938_6 Glycosyltransferase like family 2 - - - 0.0000000000000004533 79.0
CMS2_k127_3751976_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 361.0
CMS2_k127_3751976_1 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 346.0
CMS2_k127_3751976_2 Glutamine amidotransferase class-I K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009947 292.0
CMS2_k127_3751976_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000198 162.0
CMS2_k127_3751976_4 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000001812 153.0
CMS2_k127_3751976_5 cyclopropane-fatty-acyl-phospholipid synthase - - - 0.000000000000000000000000000000000000105 154.0
CMS2_k127_3751976_6 Smr domain - - - 0.00000000000000000000000000004869 119.0
CMS2_k127_3751976_7 Protein of unknown function (DUF2628) - - - 0.00000006699 59.0
CMS2_k127_376058_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 434.0
CMS2_k127_376058_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 320.0
CMS2_k127_376058_2 Virulence factor BrkB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000722 275.0
CMS2_k127_376058_3 Molecular chaperone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007102 254.0
CMS2_k127_376058_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000037 134.0
CMS2_k127_376058_5 17 kDa outer membrane surface antigen - - - 0.00000000000000000000000000000583 126.0
CMS2_k127_376058_6 Protein of unknown function (DUF2892) - - - 0.000000000000000000001111 95.0
CMS2_k127_376058_7 HlyD family secretion protein - - - 0.0000000000000000144 87.0
CMS2_k127_378372_0 Arsenical pump membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 531.0
CMS2_k127_378372_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 409.0
CMS2_k127_378372_10 - - - - 0.0009522 42.0
CMS2_k127_378372_2 Protein of unknown function (DUF692) K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 338.0
CMS2_k127_378372_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000002449 176.0
CMS2_k127_378372_4 Putative DNA-binding domain - - - 0.00000000000000000000000000000000000000000000007101 179.0
CMS2_k127_378372_5 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000003155 179.0
CMS2_k127_378372_6 DoxX - - - 0.000000000000000000000000000000000000000005342 158.0
CMS2_k127_378372_7 Protein of unknown function (DUF1109) - - - 0.0000000000000000000000000000000000004934 149.0
CMS2_k127_378372_8 IMP dehydrogenase activity - - - 0.00000000000000000000000000000001559 134.0
CMS2_k127_378372_9 Integral membrane protein - - - 0.0000000000000000006303 89.0
CMS2_k127_380007_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 2.541e-208 649.0
CMS2_k127_380007_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000002345 223.0
CMS2_k127_380007_2 COG2919 Septum formation initiator - - - 0.000000000000000000000000000000000000252 141.0
CMS2_k127_3803542_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 318.0
CMS2_k127_3803542_1 inositol monophosphatase - - - 0.00000000000000000000000001897 111.0
CMS2_k127_3803542_2 - - - - 0.0000000000000001079 83.0
CMS2_k127_3804114_0 Transmembrane secretion effector K05939 - 2.3.1.40,6.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 312.0
CMS2_k127_3804114_1 Transcriptional regulatory protein, C terminal K07657,K07659,K18144 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 299.0
CMS2_k127_3804114_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000001023 173.0
CMS2_k127_3813510_0 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 453.0
CMS2_k127_3813510_1 hydrolase (HAD superfamily) K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000008636 259.0
CMS2_k127_3813510_2 Protein of unknown function (DUF2493) - - - 0.0000000000000000000000000000000000000000000000000000000000000003122 226.0
CMS2_k127_3813510_3 Diguanylate cyclase - - - 0.00000000000002042 84.0
CMS2_k127_3831113_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 598.0
CMS2_k127_3831113_1 malonyl CoA-acyl carrier protein transacylase K00645,K15327 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 372.0
CMS2_k127_3831113_2 short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 351.0
CMS2_k127_3831113_3 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000001265 166.0
CMS2_k127_3831113_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000005607 141.0
CMS2_k127_3831113_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000001465 124.0
CMS2_k127_3831113_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000002337 111.0
CMS2_k127_3831113_7 Predicted membrane protein (DUF2232) - - - 0.0009013 48.0
CMS2_k127_3832567_0 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 569.0
CMS2_k127_3832567_1 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 331.0
CMS2_k127_3832567_2 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005496 274.0
CMS2_k127_3832567_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000001304 216.0
CMS2_k127_3832567_4 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000001468 190.0
CMS2_k127_3832567_5 COG2199 FOG GGDEF domain - - - 0.000000000000000000000001154 106.0
CMS2_k127_3832567_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000001359 84.0
CMS2_k127_3838112_0 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 344.0
CMS2_k127_3838112_1 Squalene/phytoene synthase K21678,K21679 - 2.5.1.103,4.2.3.156 0.000000000000000000000000000000000000000000000000000000000000000000000008798 252.0
CMS2_k127_3838112_2 Phytoene synthase K21678 - 2.5.1.103 0.000000000000000000000000000000000000000000000000000000000000000002871 235.0
CMS2_k127_3838112_3 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.00000000000000000000000000000000000003746 150.0
CMS2_k127_3851031_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372,K02567 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 - 0.0 1430.0
CMS2_k127_3851031_1 DNA helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 498.0
CMS2_k127_3851031_2 4Fe-4S binding domain K02574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 388.0
CMS2_k127_3851031_3 ferredoxin-type protein K02573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 351.0
CMS2_k127_3851031_4 Cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002228 276.0
CMS2_k127_3851031_5 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000000000000000000000000000000000000007351 162.0
CMS2_k127_3851031_6 AsmA-like C-terminal region K07289 - - 0.0000000000000000000000000000000000000007501 169.0
CMS2_k127_3854833_0 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 447.0
CMS2_k127_3854833_1 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000275 174.0
CMS2_k127_3854833_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000002875 86.0
CMS2_k127_3857489_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.852e-221 694.0
CMS2_k127_3857489_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 502.0
CMS2_k127_3860730_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1184.0
CMS2_k127_3862319_0 Glycosyltransferase family 87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 411.0
CMS2_k127_3862319_1 Type II secretion system (T2SS), protein F K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002229 281.0
CMS2_k127_3862319_2 Type II/IV secretion system protein K02283,K20527 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002826 272.0
CMS2_k127_3862319_3 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000886 239.0
CMS2_k127_3862319_4 Type IV leader peptidase family K02278 - 3.4.23.43 0.000000000000000000000000004707 117.0
CMS2_k127_387425_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 345.0
CMS2_k127_387425_1 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000001977 207.0
CMS2_k127_387425_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000001736 156.0
CMS2_k127_3883195_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.02e-247 769.0
CMS2_k127_3883195_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000009907 190.0
CMS2_k127_3892969_0 Mg2 and Co2 transporter CorB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 501.0
CMS2_k127_3892969_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 457.0
CMS2_k127_3892969_2 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009304 306.0
CMS2_k127_3892969_3 Shikimate kinase K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000000001336 187.0
CMS2_k127_3892969_4 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000009177 169.0
CMS2_k127_3892969_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000001624 122.0
CMS2_k127_3892969_6 Belongs to the BolA IbaG family K05527,K22066 - - 0.0000000000000000000000001737 108.0
CMS2_k127_3892969_7 Ribbon-helix-helix domain - - - 0.00000000000000000000008732 101.0
CMS2_k127_39808_0 ATPases associated with a variety of cellular activities K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 399.0
CMS2_k127_39808_1 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 394.0
CMS2_k127_39808_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 389.0
CMS2_k127_39808_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000001945 188.0
CMS2_k127_39808_4 5-carboxymethyl-2-hydroxymuconate isomerase K01826 - 5.3.3.10 0.00000000000000000000000001731 111.0
CMS2_k127_3987718_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001146 263.0
CMS2_k127_3987718_1 transcriptional regulators K22042 - - 0.000000000000000000000000000000000000004454 151.0
CMS2_k127_3987718_2 ROK family K00845,K00847 - 2.7.1.2,2.7.1.4 0.0000000000000000000000000001425 117.0
CMS2_k127_4006709_0 ABC transporter C-terminal domain K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 1.527e-243 771.0
CMS2_k127_4006709_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 469.0
CMS2_k127_4006709_2 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 408.0
CMS2_k127_4006709_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009148 252.0
CMS2_k127_4006709_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000003914 236.0
CMS2_k127_4006709_5 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000001565 192.0
CMS2_k127_4006709_6 Protein of unknown function (DUF465) - - - 0.000000000000008124 76.0
CMS2_k127_4006709_7 Protein of unknown function (DUF465) - - - 0.00000001766 57.0
CMS2_k127_4006709_8 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.0003834 51.0
CMS2_k127_4008510_0 COG0768 cell division protein FtsI penicillin-binding protein 2 K05515 - 3.4.16.4 1.563e-246 775.0
CMS2_k127_4008510_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 509.0
CMS2_k127_4008510_2 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001152 257.0
CMS2_k127_4008510_3 shape-determining protein K03571 - - 0.000000000000000000000000000000000000000000005162 168.0
CMS2_k127_4008510_4 B12 binding domain - - - 0.0000000203 56.0
CMS2_k127_4008510_5 COG2801 Transposase and inactivated derivatives - - - 0.00007901 46.0
CMS2_k127_4019034_0 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000201 284.0
CMS2_k127_4019034_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000001047 208.0
CMS2_k127_4019034_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000002872 170.0
CMS2_k127_4019034_3 methyl-accepting chemotaxis protein K07315 - 3.1.3.3 0.000000000000000000000000001491 128.0
CMS2_k127_4019034_4 - - - - 0.0000000000000000000108 98.0
CMS2_k127_4030938_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 334.0
CMS2_k127_4030938_1 7TM diverse intracellular signalling - - - 0.00000000000000000000000000000000000000000000000000000000000000000000553 247.0
CMS2_k127_4034035_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 360.0
CMS2_k127_4034035_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 311.0
CMS2_k127_4046096_0 acyl-CoA dehydrogenase K00252 - 1.3.8.6 9.926e-209 654.0
CMS2_k127_4046096_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 7.606e-206 650.0
CMS2_k127_4046096_10 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000003165 216.0
CMS2_k127_4046096_2 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 418.0
CMS2_k127_4046096_3 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 396.0
CMS2_k127_4046096_4 Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 374.0
CMS2_k127_4046096_5 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 310.0
CMS2_k127_4046096_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 299.0
CMS2_k127_4046096_7 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002135 278.0
CMS2_k127_4046096_8 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007687 272.0
CMS2_k127_4046096_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006468 273.0
CMS2_k127_4067888_0 Elongator protein 3, MiaB family, Radical SAM K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 452.0
CMS2_k127_4067888_1 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009062 355.0
CMS2_k127_4067888_2 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 329.0
CMS2_k127_4067888_3 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.00000000000000000000000000000000000000000000000000001027 194.0
CMS2_k127_4067888_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000008208 189.0
CMS2_k127_4067888_5 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000754 175.0
CMS2_k127_4067888_6 COG2867 Oligoketide cyclase lipid transport protein K18588 - - 0.000000000000000000000000000000000000000002744 160.0
CMS2_k127_4067888_7 - - - - 0.00000000000000000000000000000000000001204 151.0
CMS2_k127_4067888_8 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000004622 126.0
CMS2_k127_4067888_9 Helix-turn-helix domain K03892 - - 0.00000000000000000000000000002556 121.0
CMS2_k127_4070191_0 Apolipoprotein A1/A4/E domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 568.0
CMS2_k127_4070191_1 methyl-accepting chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 382.0
CMS2_k127_4070191_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 344.0
CMS2_k127_4070191_3 COG2202 FOG PAS PAC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002957 250.0
CMS2_k127_4070191_4 CbiX - - - 0.0000001777 56.0
CMS2_k127_4070349_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 1.026e-316 979.0
CMS2_k127_4070349_1 Glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 3.619e-227 711.0
CMS2_k127_4070349_2 Protein of unknown function (DUF1178) - - - 0.00000000001444 67.0
CMS2_k127_4077230_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 9.075e-205 648.0
CMS2_k127_4077230_1 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 499.0
CMS2_k127_4077230_10 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000006186 96.0
CMS2_k127_4077230_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 407.0
CMS2_k127_4077230_3 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 353.0
CMS2_k127_4077230_4 GTP cyclohydrolase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 310.0
CMS2_k127_4077230_5 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002861 286.0
CMS2_k127_4077230_6 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000395 230.0
CMS2_k127_4077230_7 protein affecting Mg2 Co2 transport K06195 - - 0.00000000000000000000000000000000000000000000000005242 181.0
CMS2_k127_4077230_8 - - - - 0.0000000000000000000000000000002673 131.0
CMS2_k127_4077230_9 Modulates RecA activity K03565 - - 0.0000000000000000000000000000002749 127.0
CMS2_k127_41179_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 3.006e-290 904.0
CMS2_k127_41179_1 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 423.0
CMS2_k127_41179_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000003595 182.0
CMS2_k127_41179_3 Protein of unknown function (DUF3035) - - - 0.000000000000000000000000000008258 126.0
CMS2_k127_4123075_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1557.0
CMS2_k127_4123075_1 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 385.0
CMS2_k127_4123169_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 535.0
CMS2_k127_4123169_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 338.0
CMS2_k127_4123169_2 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 329.0
CMS2_k127_4123169_3 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002725 249.0
CMS2_k127_4123169_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000007549 184.0
CMS2_k127_4123169_5 cytochrome - - - 0.00000000000000000000000000000000000005746 152.0
CMS2_k127_4123169_6 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000000002619 125.0
CMS2_k127_4123169_7 Propeptide PepSY amd peptidase M4 - - - 0.000000000007848 70.0
CMS2_k127_4123169_8 - - - - 0.00000000004425 67.0
CMS2_k127_4127830_0 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 549.0
CMS2_k127_4127830_1 - - - - 0.00000000000000000000000000228 119.0
CMS2_k127_4150068_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 518.0
CMS2_k127_4150068_1 3-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 449.0
CMS2_k127_4150068_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 331.0
CMS2_k127_4150068_3 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000324 278.0
CMS2_k127_4150068_4 COG1560 Lauroyl myristoyl acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000001339 266.0
CMS2_k127_4150068_5 ABC-type multidrug transport system, ATPase and permease K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001924 246.0
CMS2_k127_4150068_6 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000003445 228.0
CMS2_k127_4150068_7 protein conserved in bacteria K09778 - - 0.0000000000000000000000000000000000000000000000003554 186.0
CMS2_k127_4155516_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1235.0
CMS2_k127_4155516_1 signal transduction histidine kinase K13587 - 2.7.13.3 8.908e-218 706.0
CMS2_k127_4155516_2 Rad51 K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0071496 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 591.0
CMS2_k127_4155516_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 434.0
CMS2_k127_4155516_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000004559 241.0
CMS2_k127_4155516_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000001066 227.0
CMS2_k127_4155516_6 Chemotaxis phosphatase, CheZ K03414 - - 0.00000000000000000000000000000000000357 143.0
CMS2_k127_4157159_0 Reductase C-terminal K00529,K16968 - 1.14.13.111,1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 559.0
CMS2_k127_4157159_1 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002053 276.0
CMS2_k127_4157159_2 Peroxiredoxin K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000003841 188.0
CMS2_k127_4157159_3 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000002196 123.0
CMS2_k127_4178244_0 4Fe-4S dicluster domain - - - 1.697e-270 837.0
CMS2_k127_4178244_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 306.0
CMS2_k127_4178244_2 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 308.0
CMS2_k127_4178244_3 DsrE/DsrF-like family K07235 - - 0.00000000000000000000000000000000000000000000000000007641 188.0
CMS2_k127_4178244_4 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000002286 181.0
CMS2_k127_4178244_5 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000002491 158.0
CMS2_k127_4178244_6 sulfur relay protein TusB DsrH K07237 - - 0.00000000000000000000000000000000000716 138.0
CMS2_k127_4178244_7 Sulfur relay protein TusC DsrF K07236 - - 0.00000000000000000000000000000000002534 139.0
CMS2_k127_4181217_0 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006109 329.0
CMS2_k127_4181217_1 COG0451 Nucleoside-diphosphate-sugar epimerases K08679,K17947 - 5.1.3.25,5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006992 278.0
CMS2_k127_4181217_2 PFAM Bacterial regulatory proteins, luxR family K19732 - - 0.00000000000000000000000002241 118.0
CMS2_k127_4181217_3 Killing trait - - - 0.00000000000000000000000659 102.0
CMS2_k127_4182230_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 444.0
CMS2_k127_4182230_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 342.0
CMS2_k127_4182230_2 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 289.0
CMS2_k127_4182230_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000001503 138.0
CMS2_k127_4210957_0 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 427.0
CMS2_k127_4210957_1 Binding-protein-dependent transport system inner membrane component K15552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 383.0
CMS2_k127_4210957_2 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 366.0
CMS2_k127_4210957_3 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 336.0
CMS2_k127_4210957_4 COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family K18459 - 3.5.3.17 0.000000000000000000000000000000000000000000000000000000001758 201.0
CMS2_k127_4210957_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000003884 162.0
CMS2_k127_4210957_6 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000006181 90.0
CMS2_k127_421896_0 Permease family K06901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 297.0
CMS2_k127_421896_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008345 254.0
CMS2_k127_421896_2 Acts on guanine, xanthine and to a lesser extent hypoxanthine K00769 - 2.4.2.22 0.0000000000000000000000000000000000000000000000000002106 190.0
CMS2_k127_4222480_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.034e-320 990.0
CMS2_k127_4222480_1 COG0480 Translation elongation factors (GTPases) K02355 - - 1.329e-241 764.0
CMS2_k127_4222480_2 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 2.969e-210 658.0
CMS2_k127_4222480_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001411 245.0
CMS2_k127_4222480_4 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000008463 207.0
CMS2_k127_4222480_5 Protein of unknown function (DUF2892) - - - 0.000000000000000000003029 96.0
CMS2_k127_422448_0 AcrB/AcrD/AcrF family K18989 - - 1.25e-238 753.0
CMS2_k127_422448_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18990 - - 0.00000000000000000000000000000000000000000000000000000000007619 214.0
CMS2_k127_4248912_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 493.0
CMS2_k127_4248912_1 diguanylate cyclase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000006355 52.0
CMS2_k127_4249062_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008521 380.0
CMS2_k127_4249062_1 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 307.0
CMS2_k127_4249062_2 COG0694 Thioredoxin-like proteins and domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005369 256.0
CMS2_k127_4249062_3 FlgJ-related protein K03796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009812 264.0
CMS2_k127_4249062_4 xylanase chitin deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000009427 222.0
CMS2_k127_4254219_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 339.0
CMS2_k127_4254219_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 305.0
CMS2_k127_4254219_2 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 309.0
CMS2_k127_4260391_0 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000366 245.0
CMS2_k127_4260391_1 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000000009853 132.0
CMS2_k127_4260391_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000001906 105.0
CMS2_k127_4260391_3 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000001327 79.0
CMS2_k127_4260391_4 signal transduction histidine kinase - - - 0.00004682 47.0
CMS2_k127_426191_0 COG2217 Cation transport ATPase K17686 - 3.6.3.54 8.898e-256 811.0
CMS2_k127_426191_1 protein conserved in bacteria K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001031 266.0
CMS2_k127_426191_2 helix_turn_helix, mercury resistance K19591 - - 0.000000000000000000000000000000000000000000000007403 177.0
CMS2_k127_426191_3 Thioredoxin-like K07152 - - 0.0000000000000000000000000000000000000000001453 164.0
CMS2_k127_426191_4 Heavy-metal-associated domain K07213 - - 0.000000000000008132 77.0
CMS2_k127_426191_5 PilZ domain - - - 0.0003245 49.0
CMS2_k127_4271566_0 COG1138 Cytochrome c biogenesis factor K02198 - - 8.914e-273 852.0
CMS2_k127_4271566_1 Redoxin K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000611 224.0
CMS2_k127_4271566_2 COG4235 Cytochrome c biogenesis factor K02200 - - 0.000000000000000000000000000000000000000000000000000006045 204.0
CMS2_k127_4271566_3 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000000000003588 184.0
CMS2_k127_4284104_0 AcrB/AcrD/AcrF family K18989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 481.0
CMS2_k127_4284104_1 3-beta hydroxysteroid dehydrogenase K07118 - - 0.00000000000000000000000000000000000000000000000000000000000004535 220.0
CMS2_k127_4289510_0 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 470.0
CMS2_k127_4289510_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 352.0
CMS2_k127_4289510_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 346.0
CMS2_k127_4289510_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 301.0
CMS2_k127_4289510_4 transcriptional - - - 0.00000000000000000000000000000000006157 138.0
CMS2_k127_4289510_5 Helix-turn-helix XRE-family like proteins - - - 0.0000428 51.0
CMS2_k127_4293841_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.767e-271 844.0
CMS2_k127_4293841_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 563.0
CMS2_k127_4293841_10 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000000000000000000000000000004009 204.0
CMS2_k127_4293841_11 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.00000000000000000000000000000000000000000000000000000006208 201.0
CMS2_k127_4293841_12 Protein of unknown function (DUF1150) - - - 0.0000000000001493 74.0
CMS2_k127_4293841_13 Protein of unknown function (FYDLN_acid) - - - 0.000000008375 62.0
CMS2_k127_4293841_2 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 527.0
CMS2_k127_4293841_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 431.0
CMS2_k127_4293841_4 ATPases associated with a variety of cellular activities K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 417.0
CMS2_k127_4293841_5 exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 285.0
CMS2_k127_4293841_6 Cytidylate kinase K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000001422 259.0
CMS2_k127_4293841_7 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004354 246.0
CMS2_k127_4293841_8 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000000000000000000000000000001277 207.0
CMS2_k127_4293841_9 Protein conserved in bacteria K09774 - - 0.000000000000000000000000000000000000000000000000000000002537 211.0
CMS2_k127_4314712_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1607.0
CMS2_k127_4314712_1 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000081 276.0
CMS2_k127_4314712_2 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002858 264.0
CMS2_k127_4314712_3 Transcription elongation factor, N-terminal K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000002046 231.0
CMS2_k127_433470_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1141.0
CMS2_k127_4337247_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 1.901e-246 782.0
CMS2_k127_4337247_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 604.0
CMS2_k127_4337247_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 290.0
CMS2_k127_4337247_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000007597 67.0
CMS2_k127_4341952_0 - - - - 0.00001367 58.0
CMS2_k127_4359599_0 PAS PAC domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 319.0
CMS2_k127_4359599_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000001629 64.0
CMS2_k127_4368427_0 Pyridoxal-phosphate dependent enzyme K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008678 535.0
CMS2_k127_4368427_1 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 296.0
CMS2_k127_4368427_2 COG1126 ABC-type polar amino acid transport system, ATPase component K02028,K02029,K09972 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000001638 236.0
CMS2_k127_4368427_3 NUDIX domain K01515 - 3.6.1.13 0.00000000001184 66.0
CMS2_k127_4386526_0 COG0367 Asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 1.455e-252 794.0
CMS2_k127_4386526_1 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005088 266.0
CMS2_k127_4386526_2 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000002272 192.0
CMS2_k127_4386526_3 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000001389 122.0
CMS2_k127_4391004_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 369.0
CMS2_k127_4391004_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000003475 245.0
CMS2_k127_4391004_2 Protein conserved in bacteria K09928 - - 0.000000000000000000000000000000000000000000000000000000001003 207.0
CMS2_k127_4391004_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000001285 131.0
CMS2_k127_4398791_0 UPF0313 protein - - - 0.0 1097.0
CMS2_k127_4398791_1 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress K05916,K07006,K21832 - 1.14.12.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 444.0
CMS2_k127_4398791_2 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001882 273.0
CMS2_k127_4398791_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001756 232.0
CMS2_k127_4402964_0 domain, Protein - - - 1.988e-236 773.0
CMS2_k127_4402964_1 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 574.0
CMS2_k127_4402964_10 Flagellar basal body-associated protein FliL K02415 - - 0.00000000000000000000003729 98.0
CMS2_k127_4402964_11 - - - - 0.0000000000007649 78.0
CMS2_k127_4402964_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 383.0
CMS2_k127_4402964_3 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000001181 243.0
CMS2_k127_4402964_4 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000003491 217.0
CMS2_k127_4402964_5 - - - - 0.00000000000000000000000000000000000000000000000000000000001077 214.0
CMS2_k127_4402964_6 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000000000000000001561 192.0
CMS2_k127_4402964_7 PFAM MgtE intracellular - - - 0.0000000000000000000000000000000000000000000000000003391 195.0
CMS2_k127_4402964_8 Chemotaxis phosphatase, CheZ - - - 0.000000000000000000000000000000000000000000000001109 186.0
CMS2_k127_4402964_9 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000001818 125.0
CMS2_k127_4414285_0 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) K00790 - 2.5.1.7 7.533e-195 615.0
CMS2_k127_4414285_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 342.0
CMS2_k127_4414285_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000415 51.0
CMS2_k127_4428708_0 Aminotransferase K14261 - - 2.371e-215 673.0
CMS2_k127_4428708_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 552.0
CMS2_k127_4428708_2 single-stranded-DNA-specific exonuclease recJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 511.0
CMS2_k127_4428708_3 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.000000000000000000000000000002018 127.0
CMS2_k127_4428708_4 OmpA family - - - 0.00000000000000000000000000000803 133.0
CMS2_k127_4433853_0 Creatinase/Prolidase N-terminal domain K01271,K15783 - 3.4.13.9,3.5.4.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 476.0
CMS2_k127_4433853_1 threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 430.0
CMS2_k127_4433853_2 ornithine cyclodeaminase K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 424.0
CMS2_k127_4433853_3 Asp Glu hydantoin racemase K01799 - 5.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000002321 250.0
CMS2_k127_4437843_0 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000002152 224.0
CMS2_k127_4437843_1 COQ9 K18587 - - 0.000000000000000000000000000000000000000000000000002337 189.0
CMS2_k127_4437843_2 - - - - 0.00000000000000000000000000000000000000000000000006365 189.0
CMS2_k127_4445679_0 Lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 381.0
CMS2_k127_4445679_1 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000008866 205.0
CMS2_k127_4446642_0 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 492.0
CMS2_k127_4446642_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 336.0
CMS2_k127_4446642_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000001677 201.0
CMS2_k127_444758_0 3'-5' exonuclease related to the exonuclease domain of PolB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 329.0
CMS2_k127_444758_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000779 278.0
CMS2_k127_444758_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000007048 128.0
CMS2_k127_4456400_0 Response regulator receiver K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 487.0
CMS2_k127_4456400_1 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 416.0
CMS2_k127_4456400_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 379.0
CMS2_k127_4456400_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 352.0
CMS2_k127_4456400_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002575 250.0
CMS2_k127_4456400_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000001548 243.0
CMS2_k127_4456400_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000003619 95.0
CMS2_k127_4471822_0 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 378.0
CMS2_k127_4471822_1 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 344.0
CMS2_k127_4471822_2 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005423 314.0
CMS2_k127_4471822_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000001364 213.0
CMS2_k127_4471822_4 Lysin motif - - - 0.0000000000000000000000000000000000000004028 157.0
CMS2_k127_4471822_5 Cytochrome C' - - - 0.00000000000000000001331 98.0
CMS2_k127_4507748_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 603.0
CMS2_k127_4507748_1 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 348.0
CMS2_k127_4507748_2 Glycosyl transferase family 4 K02851,K13007 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 336.0
CMS2_k127_4507748_3 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000227 280.0
CMS2_k127_4507748_4 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002759 240.0
CMS2_k127_4507748_5 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000003003 175.0
CMS2_k127_4507748_6 LysE type translocator - - - 0.0000000000000000000000000000000000000000009765 167.0
CMS2_k127_4507748_7 Glycoside-hydrolase family GH114 - - - 0.00005834 50.0
CMS2_k127_4522023_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K11959 - - 6.595e-214 666.0
CMS2_k127_4522023_1 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 566.0
CMS2_k127_4522023_2 Branched-chain amino acid transport system / permease component K01998,K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002997 267.0
CMS2_k127_4540462_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 412.0
CMS2_k127_4540462_1 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 357.0
CMS2_k127_4540462_2 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000006737 202.0
CMS2_k127_4540462_3 antibiotic biosynthesis - - - 0.0000000000000000000000000000000000000005002 150.0
CMS2_k127_4540462_4 Bacterial inner membrane protein - - - 0.000000000000000000000000000000000000009512 152.0
CMS2_k127_4540462_5 Zinc-finger domain - - - 0.00000000004487 66.0
CMS2_k127_4540462_6 DsrC like protein K11179 - - 0.0001006 46.0
CMS2_k127_4547547_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.712e-248 778.0
CMS2_k127_4547547_1 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 321.0
CMS2_k127_4547547_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 294.0
CMS2_k127_4547547_3 - - - - 0.00000000000000000000000000000000000000000000001779 175.0
CMS2_k127_4547547_4 PFAM beta-lactamase domain protein - GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 - 0.000000000000000000000000000000005761 130.0
CMS2_k127_4571538_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 339.0
CMS2_k127_4571538_1 Domain of unknown function (DUF4833) - - - 0.00000000000000000000002977 107.0
CMS2_k127_4571538_2 Aminotransferase class I and II - - - 0.00001072 49.0
CMS2_k127_4571538_3 Protein of unknown function (DUF2971) - - - 0.00005647 50.0
CMS2_k127_4571538_4 myosin light chain kinase activity K12567 - 2.7.11.1 0.0003345 45.0
CMS2_k127_4599379_0 HELICc2 K03722 - 3.6.4.12 8.734e-275 867.0
CMS2_k127_4599379_1 Uncharacterised protein family (UPF0014) K02069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009315 285.0
CMS2_k127_4599379_2 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000004225 194.0
CMS2_k127_4599379_3 Hemerythrin HHE cation binding domain - - - 0.0000000003278 67.0
CMS2_k127_4632777_0 Phage gp6-like head-tail connector protein - - - 0.0000000000000000001495 93.0
CMS2_k127_4632777_3 - - - - 0.0003502 49.0
CMS2_k127_4636101_0 Thiamine pyrophosphate enzyme, central domain K01608 - 4.1.1.47 3.852e-303 937.0
CMS2_k127_4636101_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 434.0
CMS2_k127_4636101_2 Belongs to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 428.0
CMS2_k127_4636101_3 protein, possibly involved in utilization of glycolate and propanediol - - - 0.00000000000000000000000000000000003884 139.0
CMS2_k127_4667139_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 545.0
CMS2_k127_4673931_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.642e-306 947.0
CMS2_k127_4678277_0 Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 545.0
CMS2_k127_4678277_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007409 542.0
CMS2_k127_4678277_2 transmembrane transport K03442 - - 0.000000000000000000000000000000009808 134.0
CMS2_k127_4696130_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.084e-317 983.0
CMS2_k127_4696130_1 COG2913 Small protein A (tmRNA-binding) - - - 0.00000000000000000000000000000001309 131.0
CMS2_k127_4696130_2 Ubiquinol-cytochrome C chaperone K17662 - - 0.00000000000000000000000001827 116.0
CMS2_k127_4696130_3 Uncharacterized ACR, COG1399 - - - 0.00000000000000000006586 100.0
CMS2_k127_4696130_4 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000007452 65.0
CMS2_k127_469708_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000166 286.0
CMS2_k127_469708_1 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001941 244.0
CMS2_k127_469708_2 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000007546 161.0
CMS2_k127_469708_3 - - - - 0.0000000000005012 75.0
CMS2_k127_4700320_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008727 522.0
CMS2_k127_4700320_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000003672 139.0
CMS2_k127_4700320_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000003242 53.0
CMS2_k127_4703443_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 398.0
CMS2_k127_4703443_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 362.0
CMS2_k127_4703443_2 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 365.0
CMS2_k127_4703443_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 291.0
CMS2_k127_4703443_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000006803 111.0
CMS2_k127_4703443_5 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000006191 81.0
CMS2_k127_475967_0 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K09817 GO:0000041,GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005385,GO:0005488,GO:0005524,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008144,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043492,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0072509,GO:0072511,GO:0097159,GO:0097367,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 329.0
CMS2_k127_475967_1 COG4531 ABC-type Zn2 transport system, periplasmic component surface adhesin K09815 - - 0.00000000000000000000000000000000000000000000000000000000001562 218.0
CMS2_k127_475967_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000004839 190.0
CMS2_k127_475967_3 ABC-type Mn2 Zn2 transport systems permease components K09816 - - 0.0000000001514 63.0
CMS2_k127_4781355_0 Peptidase S24-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 301.0
CMS2_k127_4781355_1 tRNA synthetases class I (K) K04566 - 6.1.1.6 0.000000000000000000000000000000000000002075 148.0
CMS2_k127_4781355_2 - - - - 0.00000000000000000000000000000001826 131.0
CMS2_k127_4781355_3 - - - - 0.000000000000000000000000123 111.0
CMS2_k127_4784085_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.197e-207 652.0
CMS2_k127_4784085_1 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 564.0
CMS2_k127_4784085_2 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 512.0
CMS2_k127_4784085_3 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 495.0
CMS2_k127_4784085_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 481.0
CMS2_k127_4784085_5 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 428.0
CMS2_k127_4784085_6 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 285.0
CMS2_k127_4784085_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000002032 194.0
CMS2_k127_4784085_8 transcriptional - - - 0.0000000000000000000000000000000004722 136.0
CMS2_k127_4784085_9 - - - - 0.000000000000000000000000002664 118.0
CMS2_k127_4822891_0 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 487.0
CMS2_k127_4822891_1 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 489.0
CMS2_k127_4822891_2 Sulphur transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 383.0
CMS2_k127_4822891_3 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000007538 76.0
CMS2_k127_4843312_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 429.0
CMS2_k127_4843312_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000001626 137.0
CMS2_k127_4843312_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000006967 132.0
CMS2_k127_4882818_0 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 505.0
CMS2_k127_4882818_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003426 237.0
CMS2_k127_4882818_2 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000001375 61.0
CMS2_k127_4914569_0 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 589.0
CMS2_k127_4918899_0 ABC transporter K06158 - - 1.284e-255 802.0
CMS2_k127_4918899_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009631 485.0
CMS2_k127_4918899_2 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 484.0
CMS2_k127_4918899_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001815 284.0
CMS2_k127_4918899_4 Uncharacterized protein conserved in bacteria (DUF2066) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007812 284.0
CMS2_k127_4918899_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000004591 228.0
CMS2_k127_4918899_6 DNA polymerase III chi subunit, HolC K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000003518 188.0
CMS2_k127_4918899_7 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000000000003214 189.0
CMS2_k127_4918899_8 protein conserved in bacteria K09858 - - 0.00000000000000000000000000000000000000000000000001456 185.0
CMS2_k127_4918899_9 diguanylate cyclase - - - 0.00000000000000000000000000009443 126.0
CMS2_k127_4939754_0 Elongation factor G C-terminus K06207 GO:0000027,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006996,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009628,GO:0009987,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071826,GO:0071840 - 1.001e-275 859.0
CMS2_k127_4939754_1 COG0524 Sugar kinases, ribokinase family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 443.0
CMS2_k127_4939754_2 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000000000000000000000002544 182.0
CMS2_k127_4939754_3 Etoposide-induced protein 2.4 (EI24) - - - 0.0000000000000001795 86.0
CMS2_k127_4941287_0 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 516.0
CMS2_k127_4941287_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 337.0
CMS2_k127_4944448_0 Bacterial periplasmic substrate-binding proteins K09969 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 536.0
CMS2_k127_4944448_1 acid transport system permease K09970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006383 512.0
CMS2_k127_4944448_2 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 479.0
CMS2_k127_4944448_3 Binding-protein-dependent transport system inner membrane component K02029,K09971,K10002,K10037 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 458.0
CMS2_k127_4944448_4 COG1108 ABC-type Mn2 Zn2 transport systems, permease components K02075,K09816 - - 0.00000000000000000000000000000000000000000000000000000007721 201.0
CMS2_k127_4972303_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 531.0
CMS2_k127_4972303_1 belongs to the aldehyde dehydrogenase family K09472,K12254 - 1.2.1.54,1.2.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 357.0
CMS2_k127_4972303_2 ABC-type spermidine putrescine transport system, permease component II K11074 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0016020,GO:0016021,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000000000006355 206.0
CMS2_k127_4991003_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 5.13e-201 631.0
CMS2_k127_4991003_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 329.0
CMS2_k127_4991003_2 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008206 245.0
CMS2_k127_4991003_3 2OG-Fe(II) oxygenase superfamily K07336,K07394 - - 0.0000000000000000000000000000000000000000000000000005595 190.0
CMS2_k127_5002453_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 2.629e-246 769.0
CMS2_k127_5002453_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 609.0
CMS2_k127_5002453_2 Glycine cleavage system T protein K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 482.0
CMS2_k127_5002453_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000543 177.0
CMS2_k127_5002453_4 tryptophan synthase subunit beta - - - 0.0000000000000002363 83.0
CMS2_k127_5002453_5 - - - - 0.0000000000000005618 82.0
CMS2_k127_500725_0 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 485.0
CMS2_k127_500725_1 Methyltransferase small domain K15460 - 2.1.1.223 0.00000000000000000000000000000005035 127.0
CMS2_k127_500725_2 - - - - 0.00000000000000000006294 94.0
CMS2_k127_500725_3 Putative prokaryotic signal transducing protein - - - 0.0000000000004545 73.0
CMS2_k127_5011461_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 6.421e-308 955.0
CMS2_k127_5011461_1 NADH-ubiquinone oxidoreductase subunit G, C-terminal K00336 - 1.6.5.3 1.619e-305 949.0
CMS2_k127_5011461_10 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 338.0
CMS2_k127_5011461_11 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 304.0
CMS2_k127_5011461_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 299.0
CMS2_k127_5011461_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 295.0
CMS2_k127_5011461_14 COG2818 3-methyladenine DNA glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000002002 257.0
CMS2_k127_5011461_15 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002464 251.0
CMS2_k127_5011461_16 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000002378 237.0
CMS2_k127_5011461_17 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000001349 235.0
CMS2_k127_5011461_18 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000000000000000000000001782 218.0
CMS2_k127_5011461_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000006792 205.0
CMS2_k127_5011461_2 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 4.09e-240 750.0
CMS2_k127_5011461_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000001433 149.0
CMS2_k127_5011461_21 - - - - 0.00000000000000002584 87.0
CMS2_k127_5011461_22 - - - - 0.00000000000000003157 85.0
CMS2_k127_5011461_23 - - - - 0.0000000000000002675 91.0
CMS2_k127_5011461_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 6.06e-224 699.0
CMS2_k127_5011461_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.28e-212 663.0
CMS2_k127_5011461_5 hydrolase of the metallo-beta-lactamase superfamily K12574 - - 2.775e-208 661.0
CMS2_k127_5011461_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 548.0
CMS2_k127_5011461_7 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 505.0
CMS2_k127_5011461_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 497.0
CMS2_k127_5011461_9 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 342.0
CMS2_k127_5016783_0 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050,K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 493.0
CMS2_k127_5016783_1 NMT1-like family K02051,K15576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 368.0
CMS2_k127_5016783_2 ABC transporter K02049,K15578 - - 0.0000000000000000000537 93.0
CMS2_k127_5018288_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 518.0
CMS2_k127_5018288_1 Protein conserved in bacteria K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 381.0
CMS2_k127_5018288_2 regulation of nucleic acid-templated transcription - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 323.0
CMS2_k127_5018288_3 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000007535 216.0
CMS2_k127_5018288_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000001204 224.0
CMS2_k127_5018288_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000005114 172.0
CMS2_k127_5018288_6 thioesterase K07107 - - 0.00000000000000000003071 91.0
CMS2_k127_5018288_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000006789 87.0
CMS2_k127_5033543_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008841 254.0
CMS2_k127_5033543_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000008431 242.0
CMS2_k127_505238_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000001103 218.0
CMS2_k127_505238_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000114 113.0
CMS2_k127_505238_2 PFAM UMUC domain protein DNA-repair protein K02346,K03502 - 2.7.7.7 0.0000000000000000000008007 100.0
CMS2_k127_5057294_0 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 597.0
CMS2_k127_5057294_1 COG0456 Acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 381.0
CMS2_k127_5057294_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 346.0
CMS2_k127_5057294_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001973 240.0
CMS2_k127_5057294_4 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000000001219 187.0
CMS2_k127_5057294_5 Sulfite reductase K00381 - 1.8.1.2 0.000000000000000001956 87.0
CMS2_k127_506209_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1209.0
CMS2_k127_506209_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000001844 239.0
CMS2_k127_506209_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000000000000000000000000000000000000000000000000000008659 220.0
CMS2_k127_506209_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000002222 153.0
CMS2_k127_506209_4 Protein of unknown function (DUF1489) - - - 0.00000000000000000000000000000000000008559 148.0
CMS2_k127_506209_5 nuclease K16561 - - 0.000000000000000000000004823 107.0
CMS2_k127_506209_6 cheY-homologous receiver domain - - - 0.000000000000000007216 86.0
CMS2_k127_5062893_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001328 220.0
CMS2_k127_5062893_1 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000005861 213.0
CMS2_k127_5062893_2 COG2131 Deoxycytidylate deaminase K01493 - 3.5.4.12 0.0000000000000000001416 91.0
CMS2_k127_5062893_3 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000001564 78.0
CMS2_k127_5073276_0 phosphoenolpyruvate carboxylase activity K01595 - 4.1.1.31 3.036e-255 818.0
CMS2_k127_5073276_1 ATPases associated with a variety of cellular activities K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 380.0
CMS2_k127_5073276_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 352.0
CMS2_k127_5073276_3 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 293.0
CMS2_k127_5073276_4 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007835 264.0
CMS2_k127_5073276_5 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000486 171.0
CMS2_k127_5073276_6 ABC-type transport auxiliary lipoprotein component - - - 0.000000000000000000000000000000000000001099 154.0
CMS2_k127_5073276_7 STAS domain K04749 - - 0.0000000000000000000000001402 110.0
CMS2_k127_5073276_8 Uncharacterized protein conserved in bacteria (DUF2312) - - - 0.000000000001872 67.0
CMS2_k127_5076357_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 2.667e-250 791.0
CMS2_k127_5076357_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 6.52e-198 626.0
CMS2_k127_5076357_10 CBS domain - - - 0.000000000000000000000000000000000001644 141.0
CMS2_k127_5076357_11 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 0.00000000000000000000000006812 107.0
CMS2_k127_5076357_12 Histidine kinase - - - 0.0000000000000000000000002822 117.0
CMS2_k127_5076357_13 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.8 0.00000000000000000000000936 111.0
CMS2_k127_5076357_14 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 - - 0.00000000000000000008976 92.0
CMS2_k127_5076357_15 CbiX - - - 0.000132 48.0
CMS2_k127_5076357_16 Protein conserved in bacteria K05952 - - 0.0005003 45.0
CMS2_k127_5076357_2 COG2871 Na -transporting NADH ubiquinone oxidoreductase, subunit NqrF K00351,K16246 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000085 420.0
CMS2_k127_5076357_3 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009008 393.0
CMS2_k127_5076357_4 Rnf-Nqr subunit, membrane protein K00350 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002349 272.0
CMS2_k127_5076357_5 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000003443 259.0
CMS2_k127_5076357_6 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000000001581 242.0
CMS2_k127_5076357_7 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004378 234.0
CMS2_k127_5076357_8 - K10716 - - 0.000000000000000000000000000000000000000000000000000000000009314 211.0
CMS2_k127_5076357_9 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000001294 216.0
CMS2_k127_5079488_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 312.0
CMS2_k127_5079488_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005387 263.0
CMS2_k127_5079488_2 - - - - 0.0000000000000001077 86.0
CMS2_k127_5089920_0 Alpha beta hydrolase K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000428 230.0
CMS2_k127_5089920_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000004633 214.0
CMS2_k127_509205_0 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 336.0
CMS2_k127_509205_1 Class II release factor RF3, C-terminal domain K02837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003972 254.0
CMS2_k127_509205_2 hyperosmotic response - - - 0.0000000000000001351 87.0
CMS2_k127_5120955_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 4.66e-211 663.0
CMS2_k127_5120955_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 479.0
CMS2_k127_5120955_2 RibD C-terminal domain K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 352.0
CMS2_k127_5120955_3 Riboflavin synthase alpha chain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005727 268.0
CMS2_k127_5120955_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000005528 228.0
CMS2_k127_5120955_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000405 206.0
CMS2_k127_5120955_6 COG0698 Ribose 5-phosphate isomerase RpiB K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000003155 173.0
CMS2_k127_5120955_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000008447 169.0
CMS2_k127_5120955_8 NusB family K03625 - - 0.00000000000000000000000000000000006745 139.0
CMS2_k127_5125838_0 TopoisomeraseII K02470 - 5.99.1.3 0.0 1173.0
CMS2_k127_5125838_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 576.0
CMS2_k127_5125838_10 transcriptional regulator - - - 0.0000000000000000000000000000000000000001533 158.0
CMS2_k127_5125838_11 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000002431 113.0
CMS2_k127_5125838_12 - - - - 0.00000000000000000004177 94.0
CMS2_k127_5125838_13 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000008059 70.0
CMS2_k127_5125838_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 503.0
CMS2_k127_5125838_3 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 402.0
CMS2_k127_5125838_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 397.0
CMS2_k127_5125838_5 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 354.0
CMS2_k127_5125838_6 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 362.0
CMS2_k127_5125838_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 334.0
CMS2_k127_5125838_8 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 319.0
CMS2_k127_5125838_9 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000001653 239.0
CMS2_k127_5165752_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 526.0
CMS2_k127_5165752_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 484.0
CMS2_k127_5165752_2 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000009047 232.0
CMS2_k127_5165752_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000001995 201.0
CMS2_k127_5190273_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 409.0
CMS2_k127_5190273_1 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000004563 217.0
CMS2_k127_5190273_2 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000001224 175.0
CMS2_k127_5190273_3 COG0784 FOG CheY-like receiver - - - 0.000000000000000000000000000000000000000001489 164.0
CMS2_k127_5190273_4 oligosaccharyl transferase activity - - - 0.00000000000000000000000000002986 134.0
CMS2_k127_5190273_5 KR domain - - - 0.000000000000000000933 94.0
CMS2_k127_5190273_6 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00001857 47.0
CMS2_k127_5191034_0 Bacterial regulatory protein, Fis family K10912 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 573.0
CMS2_k127_5191034_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 480.0
CMS2_k127_5191034_2 COG1194 A G-specific DNA glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008262 376.0
CMS2_k127_5191034_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001229 268.0
CMS2_k127_5191034_4 Thioredoxin - - - 0.000000000000000000000000000000000000000002584 163.0
CMS2_k127_5191034_5 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000001926 132.0
CMS2_k127_5191034_6 Cytochrome c K08738 - - 0.00000000000000000000001465 104.0
CMS2_k127_5191034_7 Cytochrome c K08738 - - 0.0000000000000000005462 92.0
CMS2_k127_5191034_8 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000005165 74.0
CMS2_k127_5191034_9 Hpt domain - - - 0.000002015 55.0
CMS2_k127_5216913_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 5.056e-312 971.0
CMS2_k127_5216913_1 Belongs to the GPI family K01810 - 5.3.1.9 5.59e-215 680.0
CMS2_k127_5216913_2 LysE type translocator - - - 0.00000000000000000000001628 100.0
CMS2_k127_5227527_0 Nitrite and sulphite reductase 4Fe-4S domain K11180 - 1.8.99.5 4.149e-212 664.0
CMS2_k127_5227527_1 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 314.0
CMS2_k127_5227527_2 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 293.0
CMS2_k127_5227527_3 - - - - 0.0000008974 54.0
CMS2_k127_5250276_0 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 429.0
CMS2_k127_5250276_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 325.0
CMS2_k127_5250276_2 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000004125 230.0
CMS2_k127_526649_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.86e-277 859.0
CMS2_k127_526649_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000001748 163.0
CMS2_k127_526649_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000006233 126.0
CMS2_k127_5272926_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 482.0
CMS2_k127_5272926_1 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0019808,GO:0019810,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0051179,GO:0051234,GO:0070405,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 398.0
CMS2_k127_5274800_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 577.0
CMS2_k127_5274800_1 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000000002541 193.0
CMS2_k127_5284684_0 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001353 243.0
CMS2_k127_5284684_1 Putative transmembrane protein (Alph_Pro_TM) - - - 0.000000000000000000000000000000000000000000000000000000001132 209.0
CMS2_k127_5284684_2 Universal stress protein - - - 0.00000000000000000000000006402 109.0
CMS2_k127_5299087_0 Glutamate-ammonia ligase adenylyltransferase K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0031323,GO:0033238,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0070566,GO:0080090 2.7.7.42,2.7.7.89 8.25e-316 998.0
CMS2_k127_5299087_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 336.0
CMS2_k127_5299087_2 Protein of unknown function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002764 287.0
CMS2_k127_5299087_3 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000004958 212.0
CMS2_k127_5299087_4 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.0000021 57.0
CMS2_k127_5299087_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000002998 49.0
CMS2_k127_5316313_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.067e-195 624.0
CMS2_k127_5316313_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 541.0
CMS2_k127_5316313_2 Mitochondrial fission ELM1 K07276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 326.0
CMS2_k127_5316313_3 Phosphoribosyl transferase domain K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 305.0
CMS2_k127_5316313_4 Hemimethylated DNA-binding protein YccV like K11940 - - 0.00000000000000000000001926 104.0
CMS2_k127_5316313_5 TadE-like protein - - - 0.0000001513 59.0
CMS2_k127_5316313_6 TadE-like protein - - - 0.0001942 49.0
CMS2_k127_5335183_0 Na H antiporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001544 242.0
CMS2_k127_5335183_1 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000007733 151.0
CMS2_k127_5335183_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000009527 121.0
CMS2_k127_5338297_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01847 - 5.4.99.2 3.135e-316 981.0
CMS2_k127_5338297_1 Holin of 3TMs, for gene-transfer release - - - 0.000000000000000000000000000000000001572 141.0
CMS2_k127_5338297_2 Cell Wall Hydrolase - - - 0.0000000000000000000000000006682 116.0
CMS2_k127_5338297_3 - - - - 0.0001525 47.0
CMS2_k127_5351958_0 Polyphosphate kinase 2 (PPK2) - - - 2.584e-207 655.0
CMS2_k127_5351958_1 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 287.0
CMS2_k127_5351958_2 Septum formation initiator - - - 0.00000000000000000000007556 102.0
CMS2_k127_5351958_3 - - - - 0.0000000000000000000001925 102.0
CMS2_k127_5351958_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000006642 93.0
CMS2_k127_5351958_5 - - - - 0.0000000006695 65.0
CMS2_k127_5397564_0 Ion transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008893 274.0
CMS2_k127_5397564_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000254 207.0
CMS2_k127_5397564_2 helix_turn_helix multiple antibiotic resistance protein K06075 - - 0.0000000000000000000000002719 110.0
CMS2_k127_5397564_3 Protein of unknown function (DUF423) - - - 0.000000000000000000009888 96.0
CMS2_k127_5397564_4 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.000000002332 61.0
CMS2_k127_5448436_0 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000326 226.0
CMS2_k127_5448436_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000002326 204.0
CMS2_k127_5448436_2 - - - - 0.000000002535 66.0
CMS2_k127_5457247_0 helicase superfamily c-terminal domain K03732,K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 539.0
CMS2_k127_5457247_1 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 338.0
CMS2_k127_5457247_2 Histidine kinase K07716 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 305.0
CMS2_k127_5457247_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009697 260.0
CMS2_k127_5457247_4 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000009513 201.0
CMS2_k127_5457247_5 COG2199 FOG GGDEF domain K13069 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000003069 197.0
CMS2_k127_5457247_6 COG1335 Amidases related to nicotinamidase - - - 0.00000000000000000000000000000000000000000000000004045 183.0
CMS2_k127_5457247_7 Cupin domain - - - 0.000000000000000000000000000000000000001509 150.0
CMS2_k127_5457247_8 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0000000000000000000000000000000000009007 141.0
CMS2_k127_5457247_9 Belongs to the SlyX family K03745 - - 0.00000002359 59.0
CMS2_k127_5497653_0 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000001173 141.0
CMS2_k127_5497653_1 response regulator K03413 - - 0.000000000001005 72.0
CMS2_k127_5503079_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1144.0
CMS2_k127_5503079_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000437 453.0
CMS2_k127_5503079_10 Uncharacterized protein conserved in bacteria (DUF2125) - - - 0.000000000000000000000000000012 132.0
CMS2_k127_5503079_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 438.0
CMS2_k127_5503079_3 Prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 390.0
CMS2_k127_5503079_4 AAA domain, putative AbiEii toxin, Type IV TA system K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 337.0
CMS2_k127_5503079_5 Cell division protein K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002823 281.0
CMS2_k127_5503079_6 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000001417 262.0
CMS2_k127_5503079_7 chorismate mutase - - - 0.000000000000000000000000000000000000000000000000000000000007519 218.0
CMS2_k127_5503079_8 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000005784 215.0
CMS2_k127_5503079_9 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000002128 181.0
CMS2_k127_5510273_0 Aldehyde dehydrogenase family - - - 8.455e-240 747.0
CMS2_k127_5510273_1 alcohol dehydrogenase K00001,K00043 - 1.1.1.1,1.1.1.61 2.389e-196 617.0
CMS2_k127_5510273_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 335.0
CMS2_k127_5510273_3 PAS domain containing protein - - - 0.00000000000000000000000000000000000304 156.0
CMS2_k127_5510273_4 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000004046 95.0
CMS2_k127_5510273_5 Histidine kinase - - - 0.0000000000000000001783 103.0
CMS2_k127_5511542_0 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. - - - 0.0000000000000000000000000000000000000000000008371 170.0
CMS2_k127_5511542_1 Winged helix-turn-helix DNA-binding - - - 0.0000000000000000000000000000000000000000003012 166.0
CMS2_k127_5511542_2 Protein of unknown function (DUF3126) - - - 0.000000000000000000000005035 103.0
CMS2_k127_5531998_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 5.765e-225 709.0
CMS2_k127_5531998_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 589.0
CMS2_k127_5531998_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000088 456.0
CMS2_k127_5531998_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000003005 259.0
CMS2_k127_5531998_4 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000004889 249.0
CMS2_k127_5531998_5 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000303 239.0
CMS2_k127_5531998_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000003019 198.0
CMS2_k127_5531998_7 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000008333 153.0
CMS2_k127_5533347_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 1.555e-223 700.0
CMS2_k127_5533347_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 466.0
CMS2_k127_5533347_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000002529 168.0
CMS2_k127_5533347_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000002824 128.0
CMS2_k127_554560_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 571.0
CMS2_k127_554560_1 Cys/Met metabolism PLP-dependent enzyme K00643 - 2.3.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 568.0
CMS2_k127_554560_2 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001603 261.0
CMS2_k127_554560_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001208 248.0
CMS2_k127_554560_4 Putative AphA-like transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000006818 218.0
CMS2_k127_5554671_0 Uncharacterised protein conserved in bacteria (DUF2336) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 329.0
CMS2_k127_5554671_1 Permease family K06901 - - 0.000000000000000000000000000000000000000000000000000000000000003843 221.0
CMS2_k127_5554671_2 serine threonine protein kinase - - - 0.0000000000000000000000000000000008478 149.0
CMS2_k127_5554671_3 Sensory box protein response regulator - - - 0.000000000000000004569 89.0
CMS2_k127_5554671_4 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000001078 88.0
CMS2_k127_5582928_0 This protein is involved in the repair of mismatches in DNA K03555 - - 1.765e-230 726.0
CMS2_k127_5585029_0 ABC transporter transmembrane region K11004 - - 3.435e-209 676.0
CMS2_k127_5585029_1 HlyD family secretion protein K12542 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 445.0
CMS2_k127_5585029_2 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 396.0
CMS2_k127_5585029_3 Flagellar motor component K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 370.0
CMS2_k127_5585029_4 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000002963 222.0
CMS2_k127_5585029_5 flagellar motor protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000082 211.0
CMS2_k127_5585029_6 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000008018 150.0
CMS2_k127_5594666_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 3.707e-276 882.0
CMS2_k127_5594666_1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 4.403e-266 825.0
CMS2_k127_5594666_10 Stimulus-sensing domain K14980 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000000000000000000000000000000001185 169.0
CMS2_k127_5594666_11 COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism K06023 - - 0.0000000000000000000000000000000006213 138.0
CMS2_k127_5594666_12 TIGRFAM phosphocarrier, HPr family K11189 - - 0.0000000000000000000000000002885 119.0
CMS2_k127_5594666_13 Cytochrome c - - - 0.0000000000004216 79.0
CMS2_k127_5594666_14 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.0002643 43.0
CMS2_k127_5594666_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 4.144e-208 662.0
CMS2_k127_5594666_3 PAS PAC domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 583.0
CMS2_k127_5594666_4 reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 468.0
CMS2_k127_5594666_5 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 336.0
CMS2_k127_5594666_6 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 330.0
CMS2_k127_5594666_7 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000207 252.0
CMS2_k127_5594666_8 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000000000000000000000000002238 201.0
CMS2_k127_5594666_9 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000000005157 179.0
CMS2_k127_5613627_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.237e-283 882.0
CMS2_k127_5613627_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000443 83.0
CMS2_k127_5622423_0 Domain of unknown function (DUF3333) K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 520.0
CMS2_k127_5622423_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 443.0
CMS2_k127_5622423_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 398.0
CMS2_k127_5622423_3 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005221 273.0
CMS2_k127_5670432_0 3-methyl-2-oxobutanoate hydroxymethyltransferase activity K00606 GO:0003674,GO:0003824,GO:0003864,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 387.0
CMS2_k127_5670432_1 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004187 272.0
CMS2_k127_5670432_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.00000000005041 63.0
CMS2_k127_5670432_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000003626 54.0
CMS2_k127_5687474_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 449.0
CMS2_k127_5687474_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000008811 143.0
CMS2_k127_5699790_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 382.0
CMS2_k127_5699790_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000001462 264.0
CMS2_k127_5699790_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000001395 78.0
CMS2_k127_570948_0 PFAM FAD linked oxidase domain protein K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 419.0
CMS2_k127_570948_1 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 406.0
CMS2_k127_570948_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 372.0
CMS2_k127_570948_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 334.0
CMS2_k127_570948_4 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 335.0
CMS2_k127_570948_5 Chaperone SurA K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002266 281.0
CMS2_k127_570948_6 PFAM Lysine exporter protein (LYSE YGGA) K06895 - - 0.00000000000000000000000000000000000000000002255 173.0
CMS2_k127_5738498_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 397.0
CMS2_k127_5738498_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 321.0
CMS2_k127_5738498_2 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 316.0
CMS2_k127_5738498_3 Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 308.0
CMS2_k127_5738498_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000002054 160.0
CMS2_k127_5748719_0 DNA polymerase alpha chain like domain K02337 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004613 581.0
CMS2_k127_5748719_1 Permeases of the drug metabolite transporter DMT superfamily K15268 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 295.0
CMS2_k127_5748719_2 DNA polymerase K02337 - 2.7.7.7 0.00000000000000000000006869 106.0
CMS2_k127_5778524_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 575.0
CMS2_k127_5778524_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 473.0
CMS2_k127_5778524_2 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002481 270.0
CMS2_k127_5778524_3 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000001494 201.0
CMS2_k127_5778524_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000003367 154.0
CMS2_k127_5778524_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000002366 128.0
CMS2_k127_5778524_6 Protein of unknown function (DUF1236) - - - 0.00001566 56.0
CMS2_k127_5785369_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 540.0
CMS2_k127_5785369_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 306.0
CMS2_k127_5785369_2 COG0547 Anthranilate phosphoribosyltransferase - - - 0.000000000000000000000000001809 114.0
CMS2_k127_5785369_3 CbiX - - - 0.00000000000000000003285 97.0
CMS2_k127_5786693_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.62e-211 672.0
CMS2_k127_5786693_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 484.0
CMS2_k127_5786693_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 353.0
CMS2_k127_5786693_3 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003518 278.0
CMS2_k127_5786693_4 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000255 223.0
CMS2_k127_5786693_5 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000000007155 134.0
CMS2_k127_5786693_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000003246 119.0
CMS2_k127_5786693_7 Ribosomal protein L34 K02914 - - 0.0000000000000003869 78.0
CMS2_k127_5800953_0 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000000000001223 212.0
CMS2_k127_5800953_1 Cell division protein K09811 - - 0.0000000000000000000000000000000000000000000000006629 181.0
CMS2_k127_5800953_2 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000001048 160.0
CMS2_k127_5801439_0 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 594.0
CMS2_k127_5801439_1 CHC2 zinc finger K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 583.0
CMS2_k127_5801439_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 553.0
CMS2_k127_5801439_3 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000009405 183.0
CMS2_k127_5801439_4 COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ) K01955 - 6.3.5.5 0.0000000000000000000000000000000000008279 139.0
CMS2_k127_5803816_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001658 278.0
CMS2_k127_5803816_1 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000004532 211.0
CMS2_k127_5806918_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 2.557e-226 710.0
CMS2_k127_5806918_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 518.0
CMS2_k127_5806918_2 Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA K11392,K21970 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.178 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 294.0
CMS2_k127_5806918_3 DNA RNA non-specific endonuclease K01173 - - 0.00000000000000000000003179 110.0
CMS2_k127_5819930_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007622 600.0
CMS2_k127_5819930_1 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 514.0
CMS2_k127_5819930_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000006162 220.0
CMS2_k127_5819930_3 FecR protein - - - 0.000000000000000000000000000000000000000000000001842 199.0
CMS2_k127_5819930_4 Alkyl hydroperoxide reductase - - - 0.0000000000000000000000000000000000000003873 149.0
CMS2_k127_5819930_5 Tetratricopeptide repeat-like domain - - - 0.000000000000000000000000000000000000002598 160.0
CMS2_k127_5835562_0 FtsX-like permease family K02004 - - 6.183e-260 826.0
CMS2_k127_5835562_1 Aldo keto reductase - GO:0003674,GO:0003824,GO:0004033,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016491,GO:0016614,GO:0016616,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:1990928 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 424.0
CMS2_k127_5835562_2 transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 383.0
CMS2_k127_5835562_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 356.0
CMS2_k127_5835562_4 ATPases associated with a variety of cellular activities K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 325.0
CMS2_k127_5835562_5 Belongs to the BI1 family K06890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 292.0
CMS2_k127_5835562_6 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000005882 246.0
CMS2_k127_5835562_7 DnaJ-class molecular chaperone - - - 0.0000000000000000000000000000000000000000000000000000000000000000004746 235.0
CMS2_k127_5835562_8 EamA-like transporter family K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000005435 233.0
CMS2_k127_5835562_9 Flp Fap pilin component K02651 - - 0.0005026 49.0
CMS2_k127_5851638_0 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009173 343.0
CMS2_k127_5851638_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 285.0
CMS2_k127_5851638_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000009201 201.0
CMS2_k127_5851638_3 diguanylate cyclase K07216,K13590 - 2.7.7.65 0.00000000000000000000000000000000000000000000000009481 187.0
CMS2_k127_5864042_0 Di-haem cytochrome c peroxidase K00428 GO:0000302,GO:0003674,GO:0003824,GO:0004130,GO:0004601,GO:0005488,GO:0006091,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009061,GO:0009636,GO:0009987,GO:0010035,GO:0015980,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017144,GO:0019645,GO:0020037,GO:0022900,GO:0022904,GO:0042221,GO:0042493,GO:0042542,GO:0042743,GO:0044237,GO:0045333,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051716,GO:0055114,GO:0070887,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1990748 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 360.0
CMS2_k127_5864042_1 (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001553 280.0
CMS2_k127_5872549_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 0.0 1030.0
CMS2_k127_5872549_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 9.554e-214 694.0
CMS2_k127_5872549_2 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 500.0
CMS2_k127_5872549_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 435.0
CMS2_k127_5872549_4 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 392.0
CMS2_k127_5872549_5 Zn-dependent protease, contains TPR repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 377.0
CMS2_k127_5872549_6 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000002734 214.0
CMS2_k127_5872549_7 PCRF K02836 - - 0.00000000000000000000000000000000000000000000000000000000004522 208.0
CMS2_k127_5872549_8 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000000000000000000000002929 188.0
CMS2_k127_5872549_9 Domain of unknown function (DUF1849) - - - 0.00000000000000000000000000000000000004222 155.0
CMS2_k127_5891072_0 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000000000007862 179.0
CMS2_k127_5891072_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000002381 174.0
CMS2_k127_5891072_2 Transcriptional regulator, MerR family - - - 0.000000000000000000000000000000000000000000002327 171.0
CMS2_k127_5944210_0 COG2723 Beta-glucosidase 6-phospho-beta-glucosidase beta- galactosidase K05350 - 3.2.1.21 2.236e-200 632.0
CMS2_k127_5944210_1 Nucleoside 2-deoxyribosyltransferase YtoQ - - - 0.000000000002308 66.0
CMS2_k127_5960229_0 Polysulphide reductase, NrfD K00185 - - 3.093e-204 645.0
CMS2_k127_5960229_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 389.0
CMS2_k127_5960229_2 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 359.0
CMS2_k127_5960229_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004007 268.0
CMS2_k127_5960229_4 Pfam Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001254 258.0
CMS2_k127_5960229_5 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000005422 208.0
CMS2_k127_5960229_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000001507 189.0
CMS2_k127_5960229_7 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000001083 149.0
CMS2_k127_5960229_8 Cytochrome c - - - 0.0000000000000000000000000000000000004632 147.0
CMS2_k127_5981426_0 Cysteine-rich domain K00113 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 589.0
CMS2_k127_5981426_1 Dioxygenases related to 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 557.0
CMS2_k127_5981426_10 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000001614 127.0
CMS2_k127_5981426_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 504.0
CMS2_k127_5981426_3 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 341.0
CMS2_k127_5981426_4 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004844 263.0
CMS2_k127_5981426_5 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008288 243.0
CMS2_k127_5981426_6 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000008135 205.0
CMS2_k127_5981426_7 Bacterial SH3 domain K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000001692 193.0
CMS2_k127_5981426_8 Belongs to the Fur family K09826 - - 0.000000000000000000000000000000000000000000009152 167.0
CMS2_k127_5981426_9 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000005273 148.0
CMS2_k127_5987148_0 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000005446 230.0
CMS2_k127_5987148_1 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.00000000000000000000000000000000000000000000003964 173.0
CMS2_k127_5988037_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 369.0
CMS2_k127_5988037_1 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000007731 228.0
CMS2_k127_5988037_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000003047 129.0
CMS2_k127_5997463_0 belongs to the aldehyde dehydrogenase family K09472,K12254 - 1.2.1.54,1.2.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 346.0
CMS2_k127_5997463_1 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001048 229.0
CMS2_k127_5997463_2 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000000000000000003543 194.0
CMS2_k127_5997463_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000002984 92.0
CMS2_k127_601092_0 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 573.0
CMS2_k127_601092_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 362.0
CMS2_k127_601092_2 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000001143 192.0
CMS2_k127_6022443_0 Flagellar basal body rod FlgEFG protein C-terminal K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 524.0
CMS2_k127_6022443_1 Flagellar P-ring protein K02394 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 501.0
CMS2_k127_6022443_2 Flagellar basal body rod FlgEFG protein C-terminal K02390 - - 0.0000000000000000000000000000000000000000000000000000002673 210.0
CMS2_k127_6022443_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella - - - 0.00000000000000000000000002992 120.0
CMS2_k127_6022443_4 Rod binding protein - - - 0.000000000000000000000001805 108.0
CMS2_k127_6057866_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 524.0
CMS2_k127_6057866_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006788 285.0
CMS2_k127_6057866_2 Peroxide stress protein YaaA K09861 - - 0.00000000000000000000000000000000000000000000000000000000000000000001564 242.0
CMS2_k127_6057866_3 Belongs to the ArsC family - - - 0.0000000000000000000000000000000000001649 144.0
CMS2_k127_6057866_4 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000001047 138.0
CMS2_k127_6057866_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000003069 110.0
CMS2_k127_6081707_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 509.0
CMS2_k127_6081707_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000419 49.0
CMS2_k127_6098856_0 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 2.778e-284 878.0
CMS2_k127_6098856_1 AsmA family K07289,K07290 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004203 265.0
CMS2_k127_6098856_2 COG5387 Chaperone required for the assembly of the mitochondrial F1-ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006213 235.0
CMS2_k127_6098856_3 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000001591 229.0
CMS2_k127_6098856_4 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000001833 184.0
CMS2_k127_6116247_0 ABC-type multidrug transport system, ATPase and permease K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 510.0
CMS2_k127_6116247_1 Zn-dependent proteases and their inactivated homologs K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000326 237.0
CMS2_k127_6123912_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.659e-218 683.0
CMS2_k127_6123912_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007926 521.0
CMS2_k127_6123912_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 471.0
CMS2_k127_6123912_3 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 311.0
CMS2_k127_6123912_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 296.0
CMS2_k127_6123912_5 helix_turn_helix isocitrate lyase regulation K13641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 291.0
CMS2_k127_6123940_0 Class II release factor RF3, C-terminal domain K02837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005989 608.0
CMS2_k127_6123940_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 517.0
CMS2_k127_6123940_2 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00000000000000000000000000000000000000000000000000286 190.0
CMS2_k127_6123940_3 - - - - 0.00000000002488 66.0
CMS2_k127_6124398_0 DNA methylase K13581 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 574.0
CMS2_k127_6124398_1 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 307.0
CMS2_k127_6124398_2 Ribonuclease HII K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000005104 246.0
CMS2_k127_6124398_3 COG2131 Deoxycytidylate deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000004102 166.0
CMS2_k127_6139076_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 409.0
CMS2_k127_6139076_1 COG2041 Sulfite oxidase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 316.0
CMS2_k127_6139076_2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 308.0
CMS2_k127_6139076_3 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001264 279.0
CMS2_k127_6139076_4 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000003402 257.0
CMS2_k127_6139076_5 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000001541 239.0
CMS2_k127_6139076_6 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000002 201.0
CMS2_k127_6139076_7 Inositol monophosphatase - - - 0.00000000000000000000000003579 109.0
CMS2_k127_6139076_9 NYN domain - - - 0.00007796 47.0
CMS2_k127_6143574_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 1.911e-196 618.0
CMS2_k127_6143574_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 509.0
CMS2_k127_6143574_2 CoA binding domain K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 377.0
CMS2_k127_6143574_3 AFG1-like ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 326.0
CMS2_k127_6148248_0 Cytochrome D1 heme domain - - - 1.243e-235 738.0
CMS2_k127_6148248_1 radical SAM protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 584.0
CMS2_k127_6148248_2 Cytochrome D1 heme domain K19345 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 542.0
CMS2_k127_6148248_3 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 290.0
CMS2_k127_6148248_4 transcriptional regulator AsnC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000406 228.0
CMS2_k127_6148248_5 COG2010 Cytochrome c, mono- and diheme variants K15864 - 1.7.2.1,1.7.99.1 0.00000000000000000000000000000000000000000000000000000000000008929 214.0
CMS2_k127_6148248_6 heme biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000001246 188.0
CMS2_k127_6148248_7 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000002742 183.0
CMS2_k127_6148248_8 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000001607 176.0
CMS2_k127_6148248_9 Cytochrome c K19344 - - 0.0000000000000000000000004004 108.0
CMS2_k127_6149874_0 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 451.0
CMS2_k127_6149874_1 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000001633 205.0
CMS2_k127_6149874_2 Thioredoxin-like domain - - - 0.000000000000000000000000000000001022 138.0
CMS2_k127_6149874_3 LysR substrate binding domain - - - 0.00000000000000000000000007433 113.0
CMS2_k127_6149874_4 cytochrome K17230 - - 0.00000000000008789 79.0
CMS2_k127_6149874_5 Proteolipid membrane potential modulator - - - 0.0000000003574 62.0
CMS2_k127_6192860_0 Electron transfer flavoprotein K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 398.0
CMS2_k127_6192860_1 Electron transfer flavoprotein, beta subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 355.0
CMS2_k127_6192860_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000125 223.0
CMS2_k127_6192860_3 adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000001507 214.0
CMS2_k127_6192860_4 3-hydroxyacyl-coa dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000006366 193.0
CMS2_k127_6194847_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1264.0
CMS2_k127_6194847_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 466.0
CMS2_k127_6194847_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000001134 194.0
CMS2_k127_6194906_0 poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 428.0
CMS2_k127_6194906_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 364.0
CMS2_k127_6194906_2 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002663 282.0
CMS2_k127_6194906_3 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008088 226.0
CMS2_k127_6194906_4 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000001057 197.0
CMS2_k127_6194906_5 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000009479 182.0
CMS2_k127_6194906_6 Protein of unknown function (DUF1285) K09986 - - 0.000000000000000000000000000000000006685 143.0
CMS2_k127_6194906_7 - - - - 0.00000000000000000002022 97.0
CMS2_k127_6200054_0 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 324.0
CMS2_k127_6200054_1 Mitochondrial inner membrane protein - - - 0.0000000000000001912 92.0
CMS2_k127_6203033_0 alcohol dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 432.0
CMS2_k127_6203033_1 - - - - 0.000000000000000000000000000000000000000000000000000002956 194.0
CMS2_k127_6210465_0 ABC transporter transmembrane region K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 3.839e-233 732.0
CMS2_k127_6210465_1 tRNA methyl transferase K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 481.0
CMS2_k127_6210465_2 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000000000000000706 180.0
CMS2_k127_6232500_0 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 434.0
CMS2_k127_6232500_1 COG0784 FOG CheY-like receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000006769 220.0
CMS2_k127_6232500_2 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575 - 2.1.1.80 0.0000000000000000005479 93.0
CMS2_k127_6241513_0 Cytochrome C and Quinol oxidase polypeptide I - - - 4.14e-242 759.0
CMS2_k127_6241513_1 cytochrome c oxidase (Subunit II) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003634 267.0
CMS2_k127_6241513_2 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000008499 219.0
CMS2_k127_6241513_3 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000003503 159.0
CMS2_k127_6241513_4 - - - - 0.00000000006435 64.0
CMS2_k127_6253806_0 COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 - 2.7.13.3 6.21e-222 711.0
CMS2_k127_6253806_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 1.258e-199 631.0
CMS2_k127_6253806_2 Potassium transporter peripheral membrane component K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 629.0
CMS2_k127_6253806_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 348.0
CMS2_k127_6253806_4 Amino-transferase class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 325.0
CMS2_k127_6253806_5 HAD-superfamily hydrolase subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000001228 256.0
CMS2_k127_6253806_6 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000003646 204.0
CMS2_k127_6253806_7 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000000009118 156.0
CMS2_k127_6260129_0 Precorrin-3B K05934,K13541 - 2.1.1.131,3.7.1.12 4.667e-202 657.0
CMS2_k127_6260129_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 548.0
CMS2_k127_6260129_10 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008232 267.0
CMS2_k127_6260129_11 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000001357 220.0
CMS2_k127_6260129_12 Precorrin-8X K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000000000000001874 214.0
CMS2_k127_6260129_13 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000000000002986 217.0
CMS2_k127_6260129_14 precorrin-6x reductase K05895 - 1.3.1.106,1.3.1.54 0.000000000000000000000000000000000000000000000000000000007145 207.0
CMS2_k127_6260129_15 Belongs to the UPF0260 family K09160 - - 0.00000000000000000000000000000000000000000000000000000007343 202.0
CMS2_k127_6260129_16 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000004331 200.0
CMS2_k127_6260129_17 protein conserved in archaea - - - 0.00000000000000000000000000000000000000000000000004099 183.0
CMS2_k127_6260129_18 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000001469 162.0
CMS2_k127_6260129_2 de-polymerase K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 496.0
CMS2_k127_6260129_20 CobD/Cbib protein K02227 - 6.3.1.10 0.00000000000034 73.0
CMS2_k127_6260129_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 481.0
CMS2_k127_6260129_4 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 410.0
CMS2_k127_6260129_5 CbiX K03795 - 4.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 413.0
CMS2_k127_6260129_6 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 383.0
CMS2_k127_6260129_7 Precorrin-4 K05936 - 2.1.1.133,2.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 368.0
CMS2_k127_6260129_8 Precorrin-6y C5,15-methyltransferase K00595 - 2.1.1.132 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 378.0
CMS2_k127_6260129_9 CobD/Cbib protein K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 323.0
CMS2_k127_62623_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 487.0
CMS2_k127_62623_1 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 325.0
CMS2_k127_62623_2 Cell division and transport-associated protein TolA K03646 - - 0.000000000000000000000000000000000000000000000000006719 192.0
CMS2_k127_62623_3 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.000000000000000000000000000000000000000000000002261 178.0
CMS2_k127_62623_4 thioesterase K07107 - - 0.00000000001504 66.0
CMS2_k127_6268275_0 Class II vitamin B12-dependent ribonucleotide reductase K00525 - 1.17.4.1 0.0 1380.0
CMS2_k127_6268275_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 408.0
CMS2_k127_6268275_2 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 291.0
CMS2_k127_6268275_3 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000000000000000000000000008033 228.0
CMS2_k127_6268275_4 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 GO:0003674,GO:0003824,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016154,GO:0016740,GO:0016757,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000008661 149.0
CMS2_k127_6279896_0 aminopeptidase K01262 - 3.4.11.9 5.908e-211 671.0
CMS2_k127_6279896_1 argininosuccinate lyase K01755 - 4.3.2.1 2.098e-204 646.0
CMS2_k127_6279896_2 transduction histidine kinase - - - 5.418e-201 657.0
CMS2_k127_6279896_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 546.0
CMS2_k127_6279896_4 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 359.0
CMS2_k127_6279896_5 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000148 285.0
CMS2_k127_6279896_6 Thioredoxin-like - - - 0.0000000000000000000000000000000002274 141.0
CMS2_k127_6279896_7 Histidine kinase - - - 0.0000000000000000000000000000000005272 152.0
CMS2_k127_6279896_8 - - - - 0.0000000000000000008015 92.0
CMS2_k127_6279896_9 Protein of unknown function (DUF3426) - - - 0.00000000000001944 79.0
CMS2_k127_6338983_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 404.0
CMS2_k127_6338983_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005707 254.0
CMS2_k127_6338983_2 Diguanylate cyclase - - - 0.00000000000000009589 90.0
CMS2_k127_6338983_3 FecR protein - - - 0.00000000009283 74.0
CMS2_k127_6339893_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 477.0
CMS2_k127_6339893_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 442.0
CMS2_k127_6339893_2 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000002911 183.0
CMS2_k127_6339893_3 tRNA (guanine-N7-)-methyltransferase activity - - - 0.000000000000000000000000000000000000000000004522 170.0
CMS2_k127_6339893_4 conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family K00484,K09024,K14482,K16048 - 1.5.1.36 0.0000000000000000000000000000000000125 141.0
CMS2_k127_6339893_5 hyperosmotic response - - - 0.00000000000000000000000000006109 124.0
CMS2_k127_6343288_0 threonyl-tRNA aminoacylation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 579.0
CMS2_k127_6343288_1 COG0859 ADP-heptose LPS heptosyltransferase - - - 0.000000000000000000000000208 108.0
CMS2_k127_6343992_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 578.0
CMS2_k127_6343992_1 single-stranded-DNA-specific exonuclease recJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003671 281.0
CMS2_k127_6351046_0 STAS domain - - - 1.908e-216 685.0
CMS2_k127_6351870_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 5.381e-252 787.0
CMS2_k127_6351870_1 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 554.0
CMS2_k127_6351870_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 384.0
CMS2_k127_6351870_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 295.0
CMS2_k127_6351870_4 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000002709 242.0
CMS2_k127_6351870_5 Tetratricopeptide repeat - - - 0.0000000000000062 84.0
CMS2_k127_6351870_6 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000009564 56.0
CMS2_k127_6351870_7 - - - - 0.00009202 45.0
CMS2_k127_6383534_0 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 432.0
CMS2_k127_6383534_1 AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 349.0
CMS2_k127_6383534_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001728 248.0
CMS2_k127_6383534_3 Iron-containing redox enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000005658 240.0
CMS2_k127_6383534_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.000000000000000000000000000000000000000000000000000000000000000000006496 237.0
CMS2_k127_6383534_5 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000000000000000007881 172.0
CMS2_k127_6383534_6 Thermostable hemolysin - - - 0.00000000000000000000000001189 117.0
CMS2_k127_6383534_7 Membrane - - - 0.000000000000008243 85.0
CMS2_k127_6390659_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 2.266e-220 691.0
CMS2_k127_6390659_1 transhydrogenase subunit alpha K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 474.0
CMS2_k127_6390659_2 Oligopeptidase F K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000296 230.0
CMS2_k127_6390659_3 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000005643 163.0
CMS2_k127_6405636_0 Major Facilitator Superfamily K08151 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 466.0
CMS2_k127_6405636_1 MotA TolQ ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 397.0
CMS2_k127_6405636_2 OmpA family K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 359.0
CMS2_k127_6405636_3 COG2885 outer membrane protein and related peptidoglycan-associated (lipo)proteins - - - 0.00000000000000000000000000351 114.0
CMS2_k127_6405636_4 Belongs to the frataxin family K19054 - 1.16.3.1 0.00000000000000000001223 93.0
CMS2_k127_6418661_0 1-deoxy-D-xylulose-5-phosphate synthase K01662 - 2.2.1.7 2.825e-284 886.0
CMS2_k127_6418661_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 422.0
CMS2_k127_6418661_2 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 399.0
CMS2_k127_6418661_3 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 389.0
CMS2_k127_6418661_4 Polyprenyl synthetase K00795 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009536,GO:0009842,GO:0009987,GO:0016114,GO:0016740,GO:0016765,GO:0019637,GO:0033385,GO:0033386,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0090407,GO:1901576 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 363.0
CMS2_k127_6418661_5 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001189 280.0
CMS2_k127_6418661_6 AcrB/AcrD/AcrF family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000001131 199.0
CMS2_k127_6418661_7 Sulfurtransferase - - - 0.0000000000000000000005121 100.0
CMS2_k127_6418661_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000007957 85.0
CMS2_k127_6439413_0 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 4.928e-317 990.0
CMS2_k127_6439413_1 Aminoacyl tRNA synthetase class II, N-terminal domain K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 568.0
CMS2_k127_6439413_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 383.0
CMS2_k127_6439413_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000005605 236.0
CMS2_k127_6439413_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000002273 239.0
CMS2_k127_6439413_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000009301 179.0
CMS2_k127_6439413_6 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000005211 95.0
CMS2_k127_6453529_0 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 347.0
CMS2_k127_6453529_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000003366 256.0
CMS2_k127_6453529_2 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000002458 130.0
CMS2_k127_6453529_3 4Fe-4S dicluster domain K08358 - - 0.00000886 48.0
CMS2_k127_6453930_0 COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases K02230 - 6.6.1.2 0.0 1217.0
CMS2_k127_6453930_1 Cobalamin synthesis protein cobW C-terminal domain K02234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 454.0
CMS2_k127_6453930_2 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 409.0
CMS2_k127_6453930_3 EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 314.0
CMS2_k127_6453930_4 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000149 183.0
CMS2_k127_6453930_5 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000252 176.0
CMS2_k127_6453930_6 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000009484 151.0
CMS2_k127_6463753_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 299.0
CMS2_k127_6463753_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000001493 154.0
CMS2_k127_6469819_0 - - - - 0.0000000000000000000000000000000000000000000000008015 192.0
CMS2_k127_6469819_1 - - - - 0.00000000000000000000000000000001278 138.0
CMS2_k127_6469819_2 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000005132 120.0
CMS2_k127_6471212_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008961 466.0
CMS2_k127_6471212_1 cystathionine gamma-synthase activity - - - 0.000000000000000746 85.0
CMS2_k127_6475913_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1161.0
CMS2_k127_6475913_1 phosphomannomutase K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 560.0
CMS2_k127_6475913_2 Sporulation related domain K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 352.0
CMS2_k127_6475913_3 ATP-dependent Clp protease adaptor protein ClpS K06891 - - 0.0000000000000000000000000000000000000000000001007 170.0
CMS2_k127_6475913_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000001363 119.0
CMS2_k127_6475913_5 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000004454 83.0
CMS2_k127_6475913_6 Phasin protein - - - 0.0002115 50.0
CMS2_k127_6484633_0 ATPases associated with a variety of cellular activities K05833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 382.0
CMS2_k127_6484633_1 Branched-chain amino acid transport system / permease component K05832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 364.0
CMS2_k127_6484633_2 Cobalt uptake substrate-specific transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003705 258.0
CMS2_k127_6492282_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 606.0
CMS2_k127_6492282_1 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009391 386.0
CMS2_k127_6492282_2 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008974 329.0
CMS2_k127_6492282_3 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008367 316.0
CMS2_k127_6501924_0 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 295.0
CMS2_k127_6501924_1 COG0840 Methyl-accepting chemotaxis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000667 264.0
CMS2_k127_6501924_2 regulation of RNA biosynthetic process K03567 - - 0.0000000000000000000000000000000000000000000004823 172.0
CMS2_k127_6501924_3 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000000000000000000001248 115.0
CMS2_k127_6501924_5 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.000000000000000001136 85.0
CMS2_k127_6501924_6 The M ring may be actively involved in energy transduction K02409 - - 0.000009598 49.0
CMS2_k127_6538695_0 Cysteine synthase K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 479.0
CMS2_k127_6538695_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 361.0
CMS2_k127_6538695_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000483 222.0
CMS2_k127_6538695_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000287 205.0
CMS2_k127_6538695_4 ThiF family K21029 - 2.7.7.80 0.000000000000000005424 84.0
CMS2_k127_6545944_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 563.0
CMS2_k127_6545944_1 KR domain K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 360.0
CMS2_k127_6545944_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 310.0
CMS2_k127_6545944_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 287.0
CMS2_k127_6545944_4 methionine biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002172 264.0
CMS2_k127_6545944_5 Polyhydroxyalkanoate synthesis repressor - - - 0.0000000000000000000000000000000000000000000000003829 181.0
CMS2_k127_6545944_6 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000309 138.0
CMS2_k127_6545944_7 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000005457 132.0
CMS2_k127_654817_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 3.185e-248 775.0
CMS2_k127_654817_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 364.0
CMS2_k127_654817_2 Sporulation related domain - - - 0.0000000000000000000000002857 116.0
CMS2_k127_654817_3 Peptidase M50 - - - 0.000000000000112 71.0
CMS2_k127_6567756_0 PAS domain K13587 - 2.7.13.3 0.00000000000000000000000000000000000000005846 168.0
CMS2_k127_6567756_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.0000000000000000000000000013 113.0
CMS2_k127_658047_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 3.002e-297 921.0
CMS2_k127_658047_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K03431 - 5.4.2.10 1.065e-194 616.0
CMS2_k127_658047_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 372.0
CMS2_k127_658047_3 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 359.0
CMS2_k127_658047_4 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 331.0
CMS2_k127_658047_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 313.0
CMS2_k127_658047_6 Threonyl and Alanyl tRNA synthetase second additional domain K07050 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 300.0
CMS2_k127_658047_7 phenazine biosynthesis protein PhzF - - - 0.000000000000000000000000000000000000000000000000003798 187.0
CMS2_k127_658047_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000008872 166.0
CMS2_k127_658047_9 Domain of unknown function (DUF1127) - - - 0.0000008227 55.0
CMS2_k127_6585294_0 hydroxylamine reductase activity K15864 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1,1.7.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 585.0
CMS2_k127_6585294_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 435.0
CMS2_k127_6585294_2 - - - - 0.000000000000000000000000000000000001095 148.0
CMS2_k127_6585294_3 oxygen carrier activity K07216 - - 0.000000000000000000001219 100.0
CMS2_k127_6585617_0 B12 binding domain K00548 - 2.1.1.13 0.0 1590.0
CMS2_k127_6585617_1 ABC transporter K15738 - - 3.746e-249 775.0
CMS2_k127_6585617_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 436.0
CMS2_k127_6585617_3 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 415.0
CMS2_k127_6585617_4 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 331.0
CMS2_k127_6585617_5 (Lipo)protein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000159 275.0
CMS2_k127_6620143_0 FAD dependent oxidoreductase K09471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 483.0
CMS2_k127_6620143_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000006979 115.0
CMS2_k127_6620143_2 - - - - 0.00000000000000000006819 96.0
CMS2_k127_6626078_0 Type II/IV secretion system protein K02283,K20527 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 440.0
CMS2_k127_6626078_1 Pilus assembly protein CpaE K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 306.0
CMS2_k127_6686846_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 453.0
CMS2_k127_6686846_1 N-acetyl-alpha-D-glucosaminyl L-malate synthase K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000001017 57.0
CMS2_k127_6700967_0 Outer membrane efflux protein K12543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 352.0
CMS2_k127_6700967_1 Tellurite resistance protein TerB K05801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 286.0
CMS2_k127_6700967_2 COG3023 Negative regulator of beta-lactamase expression K01447 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001359 273.0
CMS2_k127_6700967_3 phosphoenolpyruvate-dependent sugar phosphotransferase system - - - 0.0000000000000001509 80.0
CMS2_k127_6700967_5 - - - - 0.000000004588 57.0
CMS2_k127_6700967_6 Sel1-like repeats. K07126 - - 0.00008682 53.0
CMS2_k127_6701956_0 Sporulation related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 350.0
CMS2_k127_6701956_1 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000002296 115.0
CMS2_k127_6705959_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 2.507e-259 807.0
CMS2_k127_6715902_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 5.346e-200 635.0
CMS2_k127_6715902_1 oligoendopeptidase F K08602 - - 0.000000000000000000000000000000000000000001761 160.0
CMS2_k127_6725272_0 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 - 1.2.4.2 0.0 1290.0
CMS2_k127_6725272_1 Heavy-metal-associated domain K01533 - 3.6.3.4 1.829e-280 883.0
CMS2_k127_6725272_10 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000664 240.0
CMS2_k127_6725272_11 protein conserved in bacteria K09921 - - 0.00000000000000000000000000000000000381 146.0
CMS2_k127_6725272_12 FixH - - - 0.00000000000000000000000000000000006952 139.0
CMS2_k127_6725272_13 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000001005 133.0
CMS2_k127_6725272_14 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000002291 128.0
CMS2_k127_6725272_15 cytochrome oxidase maturation protein - - - 0.000000000000004185 79.0
CMS2_k127_6725272_16 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.00000000002801 67.0
CMS2_k127_6725272_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.416e-270 837.0
CMS2_k127_6725272_3 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 7.611e-196 620.0
CMS2_k127_6725272_4 Nitrogen fixation protein fixG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 579.0
CMS2_k127_6725272_5 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 533.0
CMS2_k127_6725272_6 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 369.0
CMS2_k127_6725272_7 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 350.0
CMS2_k127_6725272_8 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 344.0
CMS2_k127_6725272_9 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003582 286.0
CMS2_k127_673562_0 Ammonium Transporter Family - - - 4.598e-244 757.0
CMS2_k127_673562_1 Serine/Threonine protein kinases, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 364.0
CMS2_k127_673562_2 Sec-independent protein translocase protein (TatC) K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 293.0
CMS2_k127_6740807_0 Flagella basal body rod protein K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002034 268.0
CMS2_k127_6740807_1 Belongs to the flagella basal body rod proteins family K02391 - - 0.000000000000000000000000000000000000000000000000000000000000000000003247 244.0
CMS2_k127_6786512_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 457.0
CMS2_k127_6786512_1 Zinc-binding dehydrogenase K00001,K19745 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 397.0
CMS2_k127_6786512_2 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009245 272.0
CMS2_k127_6786512_3 Dihaem cytochrome c - - - 0.000000000000000000000000000006323 126.0
CMS2_k127_6786512_4 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000000000000000000374 129.0
CMS2_k127_6786512_5 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000001008 91.0
CMS2_k127_6786512_6 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0001065 48.0
CMS2_k127_6800034_0 Beta propeller repeats in Physarum polycephalum tectonins, Limulus lectin L-6 and animal hypothetical proteins. - - - 2.372e-242 774.0
CMS2_k127_6800034_1 Bacterial type II and III secretion system protein - - - 9.64e-236 737.0
CMS2_k127_6800034_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000005575 184.0
CMS2_k127_6800034_3 PFAM Ankyrin K06867 - - 0.000001268 55.0
CMS2_k127_680402_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 317.0
CMS2_k127_680402_1 diguanylate cyclase K07216,K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 317.0
CMS2_k127_680402_2 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 313.0
CMS2_k127_680402_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004479 267.0
CMS2_k127_680402_4 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000002228 228.0
CMS2_k127_6806930_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000001352 269.0
CMS2_k127_6806930_1 COG2111 Multisubunit Na H antiporter, MnhB subunit K05566 - - 0.0000000000000000000000000000000000000000000000000000000000895 209.0
CMS2_k127_6806930_2 COG2111 Multisubunit Na H antiporter, MnhB subunit - - - 0.0000000000000000000000000000000000000000000000000002645 190.0
CMS2_k127_6806930_3 Na+/H+ ion antiporter subunit K05569 - - 0.0000000000000000000000000000000000000003255 156.0
CMS2_k127_6806930_4 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000008978 136.0
CMS2_k127_6806930_5 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.000000000000000000000000003104 114.0
CMS2_k127_6806930_6 monovalent cation proton antiporter, MnhG PhaG subunit K05571 - - 0.0000000000000000000000004644 114.0
CMS2_k127_6806930_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000000000000000003302 93.0
CMS2_k127_6822432_0 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 359.0
CMS2_k127_6822432_1 Protein of unknown function (DUF3050) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 294.0
CMS2_k127_6822432_2 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000001045 202.0
CMS2_k127_6822432_3 Transglycosylase SLT domain - - - 0.00000000000001478 80.0
CMS2_k127_682924_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1241.0
CMS2_k127_682924_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 3.882e-257 806.0
CMS2_k127_682924_10 Gram-negative porin K08720 - - 0.0000000000000000000000000000000002056 147.0
CMS2_k127_682924_11 Lipopolysaccharide-assembly K03643 - - 0.000000000000001725 85.0
CMS2_k127_682924_12 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000001356 58.0
CMS2_k127_682924_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 497.0
CMS2_k127_682924_3 Chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 390.0
CMS2_k127_682924_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 355.0
CMS2_k127_682924_5 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000058 344.0
CMS2_k127_682924_6 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 299.0
CMS2_k127_682924_7 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000003715 214.0
CMS2_k127_682924_8 Ferredoxin, 2Fe-2S - - - 0.000000000000000000000000000000000000000000000001288 177.0
CMS2_k127_682924_9 Domain of unknown function (DUF3576) - - - 0.00000000000000000000000000000000000000000000006295 175.0
CMS2_k127_683329_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 3.899e-221 700.0
CMS2_k127_683329_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 589.0
CMS2_k127_683329_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 377.0
CMS2_k127_683329_3 COG0471 Di- and tricarboxylate transporters - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006477 245.0
CMS2_k127_6852815_0 PAS fold K07716 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 404.0
CMS2_k127_6852815_1 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000007002 193.0
CMS2_k127_6852815_2 Homoserine dehydrogenase, NAD binding domain - - - 0.000000000000000000000000004955 115.0
CMS2_k127_6856983_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 516.0
CMS2_k127_6856983_1 4Fe-4S dicluster domain K16887 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 473.0
CMS2_k127_6859720_0 Carboxypeptidase Taq (M32) metallopeptidase K01299 - 3.4.17.19 1.711e-202 641.0
CMS2_k127_6859720_1 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 6.515e-195 631.0
CMS2_k127_6859720_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000731 239.0
CMS2_k127_6859720_11 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000001745 236.0
CMS2_k127_6859720_12 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000143 214.0
CMS2_k127_6859720_13 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000002356 183.0
CMS2_k127_6859720_14 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000314 166.0
CMS2_k127_6859720_15 cytochrome c oxidase, subunit III K02276 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.0000000000000000000000000000000000005255 149.0
CMS2_k127_6859720_16 Cytochrome C oxidase subunit II, transmembrane domain K02275 - 1.9.3.1 0.000000000000000000000000000000003191 139.0
CMS2_k127_6859720_17 Protein of unknown function (DUF420) K08976 - - 0.000000000000000000000000000009824 125.0
CMS2_k127_6859720_2 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 586.0
CMS2_k127_6859720_3 Belongs to the peptidase M16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 502.0
CMS2_k127_6859720_4 Belongs to the heme-copper respiratory oxidase family K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 494.0
CMS2_k127_6859720_5 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 472.0
CMS2_k127_6859720_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 343.0
CMS2_k127_6859720_7 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 343.0
CMS2_k127_6859720_8 COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008877 292.0
CMS2_k127_6859720_9 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003055 245.0
CMS2_k127_6873003_0 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 1.261e-234 733.0
CMS2_k127_6873003_1 Glutamate-cysteine ligase family 2(GCS2) K01919 - 6.3.2.2 2.158e-210 661.0
CMS2_k127_6873003_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 505.0
CMS2_k127_6873003_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003722 256.0
CMS2_k127_6873003_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000004965 213.0
CMS2_k127_6873003_5 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000003131 158.0
CMS2_k127_6874733_0 Oxidative deamination of D-amino acids K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 396.0
CMS2_k127_6874733_1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000006476 179.0
CMS2_k127_6874733_2 integral membrane protein - - - 0.00000000000000000000000000000000000000003049 156.0
CMS2_k127_6874733_3 - - - - 0.0000000000000000000000000001147 127.0
CMS2_k127_6874733_4 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.0000000000000000000000000005036 127.0
CMS2_k127_6894648_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.442e-315 972.0
CMS2_k127_6894648_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 571.0
CMS2_k127_6894648_10 NnrU protein - - - 0.000000000000000000000000000000000000000000000000000000000000004623 223.0
CMS2_k127_6894648_11 protein conserved in bacteria K09858 - - 0.0000000000000000000000000000000000000000000000000000142 193.0
CMS2_k127_6894648_12 COG1846 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000005156 171.0
CMS2_k127_6894648_13 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000288 137.0
CMS2_k127_6894648_14 YGGT family K02221 - - 0.0000000000000000000001457 100.0
CMS2_k127_6894648_15 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000004423 99.0
CMS2_k127_6894648_16 Recombinase zinc beta ribbon domain K06400 - - 0.000000004202 59.0
CMS2_k127_6894648_18 Histidine kinase K01768,K01991,K03413 - 4.6.1.1 0.0002646 50.0
CMS2_k127_6894648_2 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 561.0
CMS2_k127_6894648_3 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008138 469.0
CMS2_k127_6894648_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 441.0
CMS2_k127_6894648_5 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 421.0
CMS2_k127_6894648_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 376.0
CMS2_k127_6894648_7 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 320.0
CMS2_k127_6894648_8 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 301.0
CMS2_k127_6894648_9 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000005205 236.0
CMS2_k127_696698_0 Oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 579.0
CMS2_k127_696698_1 Ergosterol biosynthesis ERG4/ERG24 family - - - 0.0000000000000000000000004305 106.0
CMS2_k127_6983461_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 5.999e-270 838.0
CMS2_k127_6983461_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 314.0
CMS2_k127_6983461_2 Acetolactate synthase small K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000004905 256.0
CMS2_k127_6989262_0 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 554.0
CMS2_k127_6989262_1 Ethanolamine utilisation - propanediol utilisation K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 421.0
CMS2_k127_6989262_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 323.0
CMS2_k127_6989262_3 CorA-like Mg2+ transporter protein K03284,K16074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002393 284.0
CMS2_k127_6989262_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005193 266.0
CMS2_k127_6989262_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000004499 241.0
CMS2_k127_6989262_6 Glycosyltransferase family 87 - - - 0.000000000000004356 79.0
CMS2_k127_6989262_8 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.0000000000004708 69.0
CMS2_k127_7005921_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.443e-205 644.0
CMS2_k127_7005921_1 Dehydroquinase class II K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000006698 198.0
CMS2_k127_7005921_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000004675 161.0
CMS2_k127_7009364_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008457 561.0
CMS2_k127_7009364_1 Branched-chain amino acid transport system permease K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 444.0
CMS2_k127_7009364_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 397.0
CMS2_k127_7009364_3 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 380.0
CMS2_k127_7009364_4 amino acid K01996 - - 0.0000000000001372 77.0
CMS2_k127_7028289_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.258e-278 871.0
CMS2_k127_7028289_1 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 409.0
CMS2_k127_7028289_2 Sulfite exporter TauE/SafE K07090 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000005815 151.0
CMS2_k127_7028289_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000001618 134.0
CMS2_k127_7028289_4 relative of glutathione S-transferase, MAPEG superfamily K07136 - - 0.0000000000000103 79.0
CMS2_k127_7028289_5 Glycine zipper 2TM domain - - - 0.000000000002025 72.0
CMS2_k127_7038207_0 COG3970 Fumarylacetoacetate (FAA) hydrolase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 372.0
CMS2_k127_7038207_1 transport system periplasmic component K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 359.0
CMS2_k127_7038207_2 FCD - - - 0.0000000000000000000000000000000000000000000000000000003464 202.0
CMS2_k127_7041332_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 359.0
CMS2_k127_7041332_1 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 345.0
CMS2_k127_7041332_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 335.0
CMS2_k127_7041332_3 AAA domain, putative AbiEii toxin, Type IV TA system K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004797 280.0
CMS2_k127_7041332_4 Molybdenum Cofactor Synthesis C K03639 - 4.1.99.22 0.00000000000000000000000000004391 117.0
CMS2_k127_7046903_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.816e-223 703.0
CMS2_k127_7046903_1 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 433.0
CMS2_k127_7046903_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000006259 248.0
CMS2_k127_7046903_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000003126 99.0
CMS2_k127_714881_0 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008621 610.0
CMS2_k127_714881_1 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 310.0
CMS2_k127_714881_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 0.00000000000000000000000000000000000000001106 154.0
CMS2_k127_726534_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 485.0
CMS2_k127_726534_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000001197 169.0
CMS2_k127_726534_2 Dihaem cytochrome c - - - 0.0000000000000000002554 91.0
CMS2_k127_738107_0 FHIPEP family K02400 - - 4.382e-311 966.0
CMS2_k127_738107_1 Sigma-54 interaction domain K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 611.0
CMS2_k127_738107_2 Flagellar M-ring protein C-terminal K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 509.0
CMS2_k127_738107_3 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 496.0
CMS2_k127_738107_4 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 366.0
CMS2_k127_738107_5 MotA/TolQ/ExbB proton channel family K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 353.0
CMS2_k127_738107_6 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 - - 0.00000000000000000000000000000000000000000002992 164.0
CMS2_k127_738107_7 Flagellar basal body rod FlgEFG protein C-terminal K02390 - - 0.00000000000000000000000000000000000000000003057 172.0
CMS2_k127_738107_8 Flagellar assembly protein FliH K02411 - - 0.000000000000000000004466 105.0
CMS2_k127_738107_9 Protein of unknown function (DUF1153) - - - 0.000000000000000003003 88.0
CMS2_k127_738309_0 methyl-accepting chemotaxis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007809 313.0
CMS2_k127_738309_1 COG2202 FOG PAS PAC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001065 263.0
CMS2_k127_738309_2 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.000000000000000000000000000006397 120.0
CMS2_k127_739465_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 397.0
CMS2_k127_739465_1 Pfam:DUF955 K07110 - - 0.000000000000000000000000000000000000000000000000000000000000000000002502 241.0
CMS2_k127_739465_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000000000000000000000006979 152.0
CMS2_k127_739465_3 Nickel-dependent hydrogenase - - - 0.0000151 51.0
CMS2_k127_741022_0 succinylglutamate desuccinylase aspartoacylase K15784 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.1.125 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 479.0
CMS2_k127_741022_1 Aldehyde dehydrogenase family K15786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007466 385.0
CMS2_k127_741022_2 Creatinase/Prolidase N-terminal domain K01271,K15783 - 3.4.13.9,3.5.4.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003593 265.0
CMS2_k127_741022_3 helix_turn_helix ASNC type K15782 - - 0.000000000000000000000000000000000000000000000000000000009403 207.0
CMS2_k127_753026_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 381.0
CMS2_k127_753026_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 365.0
CMS2_k127_753026_2 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000058 140.0
CMS2_k127_760180_0 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 314.0
CMS2_k127_760180_1 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000001525 110.0
CMS2_k127_760180_2 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000008184 103.0
CMS2_k127_765397_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 8.266e-234 727.0
CMS2_k127_765397_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000001437 142.0
CMS2_k127_765397_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000001396 98.0
CMS2_k127_780710_0 COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family K18459 - 3.5.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 353.0
CMS2_k127_780710_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000403 229.0
CMS2_k127_780710_2 COG1530 Ribonucleases G and E K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000004154 242.0
CMS2_k127_780710_3 Translation initiation factor 1A / IF-1 K02518 - - 0.00000000000000000000000000000000001779 135.0
CMS2_k127_780710_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.0000000000000000000009274 95.0
CMS2_k127_780710_5 zinc ion binding K00859,K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 2.7.1.24 0.0000000000000001869 81.0
CMS2_k127_780710_6 Resolvase - - - 0.0000001012 57.0
CMS2_k127_78559_0 TIGRFAM MazG family protein K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009688 308.0
CMS2_k127_78559_1 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000269 277.0
CMS2_k127_78559_2 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000004605 190.0
CMS2_k127_78559_3 - - - - 0.000000000000001677 85.0
CMS2_k127_796625_0 PD-(D/E)XK nuclease superfamily K16898 - 3.6.4.12 1.365e-220 707.0
CMS2_k127_80_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916 - 6.3.1.5 5.047e-228 719.0
CMS2_k127_80_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 569.0
CMS2_k127_80_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 502.0
CMS2_k127_80_3 - - - - 0.0000000000000000000000000001362 125.0
CMS2_k127_80_4 - - - - 0.00000000000000007664 89.0
CMS2_k127_818384_0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000004007 241.0
CMS2_k127_818384_1 Diguanylate cyclase - - - 0.000005709 57.0
CMS2_k127_82673_0 membrane protein terc - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 268.0
CMS2_k127_82673_1 transcriptional regulator K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004541 240.0
CMS2_k127_82673_2 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000000006924 211.0
CMS2_k127_82673_3 S4 RNA-binding domain K04762 - - 0.0000000000000000000000000000000000000002254 153.0
CMS2_k127_82673_4 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000003445 149.0
CMS2_k127_82673_6 peptidase M48, Ste24p - - - 0.00000000000000000000001327 106.0
CMS2_k127_829298_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 5.028e-224 702.0
CMS2_k127_829298_1 Isocitrate/isopropylmalate dehydrogenase K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 524.0
CMS2_k127_829298_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 359.0
CMS2_k127_829298_3 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 323.0
CMS2_k127_829298_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000003715 200.0
CMS2_k127_829298_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000004003 181.0
CMS2_k127_829298_6 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000000105 154.0
CMS2_k127_829298_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000236 128.0
CMS2_k127_866859_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000004305 161.0
CMS2_k127_866859_1 17 kDa outer membrane surface antigen - - - 0.0000000000003118 78.0
CMS2_k127_866859_2 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0000000003866 68.0
CMS2_k127_881558_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 294.0
CMS2_k127_881558_1 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000009881 222.0
CMS2_k127_881558_2 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000003564 152.0
CMS2_k127_881558_3 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000007703 111.0
CMS2_k127_881558_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000006819 101.0
CMS2_k127_881558_5 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000002972 89.0
CMS2_k127_888409_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.477e-234 728.0
CMS2_k127_888409_1 oxygen carrier activity - - - 0.00000000000000000000000000000000003513 138.0
CMS2_k127_888409_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000005083 132.0
CMS2_k127_888409_3 Histidine phosphatase superfamily (branch 1) K08296 - - 0.00000000000000000000000000000008798 131.0
CMS2_k127_888409_4 Histidine phosphatase superfamily (branch 1) K08296 - - 0.000000000000000000003625 99.0
CMS2_k127_888409_5 Ultra-violet resistance protein B K03702 - - 0.0000000000009374 68.0
CMS2_k127_908466_0 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001548 284.0
CMS2_k127_908466_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000108 266.0
CMS2_k127_908466_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000005646 227.0
CMS2_k127_908466_3 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000004445 160.0
CMS2_k127_908466_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000007957 69.0
CMS2_k127_925956_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 391.0
CMS2_k127_925956_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 293.0
CMS2_k127_925956_2 Putative heavy-metal-binding - - - 0.00000000000000000000001278 101.0
CMS2_k127_925956_3 Rhomboid family K19225 - 3.4.21.105 0.00000000001821 76.0
CMS2_k127_937536_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.722e-288 904.0
CMS2_k127_937536_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 361.0
CMS2_k127_937536_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000001817 158.0
CMS2_k127_937536_3 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000007935 146.0
CMS2_k127_937536_4 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000001207 100.0
CMS2_k127_939668_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 1.907e-297 925.0
CMS2_k127_939668_1 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 410.0
CMS2_k127_939668_2 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 338.0
CMS2_k127_939668_3 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000003547 66.0
CMS2_k127_942473_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 379.0
CMS2_k127_942473_1 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 336.0
CMS2_k127_942473_2 PFAM Enoyl-CoA hydratase isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 289.0
CMS2_k127_942473_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001035 261.0
CMS2_k127_942473_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008481 239.0
CMS2_k127_942473_5 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000003335 229.0
CMS2_k127_942473_6 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000001773 166.0
CMS2_k127_942473_7 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000005297 115.0
CMS2_k127_948832_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 361.0
CMS2_k127_948832_1 ATP synthase subunit beta K00574,K18164 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 359.0
CMS2_k127_948832_2 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001288 272.0
CMS2_k127_948832_3 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000005198 90.0
CMS2_k127_975522_0 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 2.586e-210 661.0
CMS2_k127_975522_1 Belongs to the peptidase S1C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 511.0
CMS2_k127_975522_2 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 369.0
CMS2_k127_975522_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005039 246.0
CMS2_k127_975522_4 CrcB-like protein, Camphor Resistance (CrcB) K06199 - - 0.000000000000000000000000000000001432 133.0
CMS2_k127_976664_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 7.696e-258 812.0
CMS2_k127_976664_1 RecF/RecN/SMC N terminal domain K03529 - - 8.265e-205 659.0
CMS2_k127_976664_10 Peptidase inhibitor I78 family - - - 0.000005539 52.0
CMS2_k127_976664_2 RecF/RecN/SMC N terminal domain K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 493.0
CMS2_k127_976664_3 ATP synthase A chain K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 348.0
CMS2_k127_976664_4 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 334.0
CMS2_k127_976664_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000005567 140.0
CMS2_k127_976664_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000007204 138.0
CMS2_k127_976664_7 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000001464 113.0
CMS2_k127_976664_8 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000003544 106.0
CMS2_k127_976664_9 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000000000000001879 85.0
CMS2_k127_986206_0 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 464.0
CMS2_k127_986206_1 methyl-accepting chemotaxis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 317.0
CMS2_k127_986206_2 COG1393 Arsenate reductase and related proteins, glutaredoxin family K00537 - 1.20.4.1 0.000000000000000000000000000000000000000004019 156.0
CMS2_k127_986206_3 Modulates RecA activity K03565 - - 0.00000000001125 66.0
CMS2_k127_986206_4 Protoglobin - - - 0.00000462 48.0