Overview

ID MAG00409
Name CMS2_bin.12
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order JABURT01
Family JABURT01
Genus JABURT01
Species
Assembly information
Completeness (%) 90.35
Contamination (%) 1.42
GC content (%) 53.0
N50 (bp) 16,614
Genome size (bp) 2,623,041

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2542

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1048437_0 peptidase K01414 - 3.4.24.70 1.431e-312 969.0
CMS2_k127_1048437_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 4.85e-290 896.0
CMS2_k127_1048437_10 Acid phosphatase homologues K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 455.0
CMS2_k127_1048437_11 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 409.0
CMS2_k127_1048437_12 COG1943 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 376.0
CMS2_k127_1048437_13 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 360.0
CMS2_k127_1048437_14 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 350.0
CMS2_k127_1048437_15 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 338.0
CMS2_k127_1048437_16 chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 321.0
CMS2_k127_1048437_17 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 296.0
CMS2_k127_1048437_18 helical bimodular (HBM) domain K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 308.0
CMS2_k127_1048437_19 chemotaxis K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 304.0
CMS2_k127_1048437_2 PFAM aminotransferase class-III K01845 - 5.4.3.8 1.394e-212 668.0
CMS2_k127_1048437_20 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001811 282.0
CMS2_k127_1048437_21 PFAM Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000163 241.0
CMS2_k127_1048437_22 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000003353 224.0
CMS2_k127_1048437_23 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000003367 216.0
CMS2_k127_1048437_24 peptidase S16, lon K07157 - - 0.000000000000000000000000000000000000000000000000000001913 197.0
CMS2_k127_1048437_25 5TMR of 5TMR-LYT - - - 0.0000000000000000000000000000000000000000000000000004937 203.0
CMS2_k127_1048437_26 - - - - 0.000000000000000000000000000000000000000000000012 177.0
CMS2_k127_1048437_27 PhoQ Sensor - - - 0.0000000000000000000000000000000001558 144.0
CMS2_k127_1048437_28 cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000002571 138.0
CMS2_k127_1048437_29 membrane K08973 - - 0.00000000000000000000006665 100.0
CMS2_k127_1048437_3 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 3.622e-208 655.0
CMS2_k127_1048437_30 - - - - 0.000000000000000000008952 98.0
CMS2_k127_1048437_31 - - - - 0.000000000000000001261 92.0
CMS2_k127_1048437_32 Protein of unknown function (DUF2390) - - - 0.000000000000000001405 93.0
CMS2_k127_1048437_33 Super-infection exclusion protein B - - - 0.00000000000000001386 89.0
CMS2_k127_1048437_34 TIR domain - - - 0.0000000004657 60.0
CMS2_k127_1048437_35 Tetratricopeptide repeat - - - 0.000000001927 70.0
CMS2_k127_1048437_37 - - - - 0.0000006433 60.0
CMS2_k127_1048437_4 Domain of unknown function (DUF4931) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 574.0
CMS2_k127_1048437_5 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 531.0
CMS2_k127_1048437_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 511.0
CMS2_k127_1048437_7 Histidine Phosphotransfer domain K11527 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008686 517.0
CMS2_k127_1048437_8 RESPONSE REGULATOR receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 485.0
CMS2_k127_1048437_9 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 441.0
CMS2_k127_1048910_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1347.0
CMS2_k127_1048910_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 4.109e-206 646.0
CMS2_k127_1048910_2 Modulates RecA activity K03565 - - 0.000000000000000000000000000000007266 132.0
CMS2_k127_1048910_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000002623 118.0
CMS2_k127_1048910_4 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.0000000000000000000000001001 111.0
CMS2_k127_1048910_5 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005979,GO:0006109,GO:0006139,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010675,GO:0010677,GO:0010906,GO:0010962,GO:0016070,GO:0016071,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032881,GO:0032885,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043255,GO:0043467,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045719,GO:0045912,GO:0045947,GO:0046483,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0062012,GO:0065007,GO:0070873,GO:0070874,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.0000000000000000000000006156 107.0
CMS2_k127_1048910_6 PilZ domain - - - 0.00000000000001984 83.0
CMS2_k127_1048910_7 FlgN protein K02399 - - 0.000000004772 64.0
CMS2_k127_1048910_8 Anti-sigma-28 factor, FlgM K02398 - - 0.000000007512 61.0
CMS2_k127_1053276_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016874,GO:0016879,GO:0016884,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.5.3 0.0 1301.0
CMS2_k127_1053276_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 2.2e-228 716.0
CMS2_k127_1053276_2 Permease YjgP YjgQ K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000003003 244.0
CMS2_k127_1053276_3 permease K07091 - - 0.00000000000000000000000000000000000000000000000000000000000007955 226.0
CMS2_k127_1053276_4 Uncharacterized conserved protein (DUF2173) - - - 0.0000000000000000000000000000000000000001579 153.0
CMS2_k127_1053276_5 Uncharacterized conserved protein (DUF2173) - - - 0.0000000000000000000000000000000000000001785 152.0
CMS2_k127_1053276_6 Uncharacterized conserved protein (DUF2173) - - - 0.000000000000000000000000000000000000008704 147.0
CMS2_k127_1053276_7 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.00000000000000000000000000000634 122.0
CMS2_k127_1053276_8 pfam rdd - - - 0.000000000000000009116 89.0
CMS2_k127_1062400_0 COG0643 Chemotaxis protein histidine kinase and related kinases K03407 GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009892,GO:0009893,GO:0009987,GO:0010562,GO:0010604,GO:0010605,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019220,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0031323,GO:0031324,GO:0031325,GO:0031399,GO:0031400,GO:0031401,GO:0032101,GO:0032268,GO:0032269,GO:0032270,GO:0032879,GO:0032991,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035556,GO:0036211,GO:0040011,GO:0040012,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045937,GO:0046777,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0050920,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0098561,GO:0140096,GO:1901564,GO:1901873,GO:1901875,GO:1902021,GO:2000145 2.7.13.3 5.701e-216 690.0
CMS2_k127_1062400_1 TIGRFAM ATPase, FliI YscN family K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 602.0
CMS2_k127_1062400_10 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000000003347 201.0
CMS2_k127_1062400_11 PFAM Flagellar assembly protein FliH K02411 - - 0.0000000000000000000000000000000000000001083 160.0
CMS2_k127_1062400_12 Flagellar protein FliS K02422 GO:0001539,GO:0003674,GO:0005198,GO:0006928,GO:0008150,GO:0009987,GO:0040011,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.00000000000000000000000000000000001509 140.0
CMS2_k127_1062400_13 Flagellar hook-length control protein K02414 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.00000000000000000000000002593 124.0
CMS2_k127_1062400_14 Flagellar hook-basal body K02408 - - 0.0000000000000000000002184 100.0
CMS2_k127_1062400_15 FlaG protein K06603 - - 0.000000000000009918 79.0
CMS2_k127_1062400_16 Flagellar FliJ protein - - - 0.00000000000001661 79.0
CMS2_k127_1062400_17 Atypical PilZ domain, cyclic di-GMP receptor - - - 0.0000000000001692 78.0
CMS2_k127_1062400_18 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000005527 68.0
CMS2_k127_1062400_2 PFAM response regulator receiver K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 526.0
CMS2_k127_1062400_3 sigma54 specific, transcriptional regulator, Fis family K10941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 459.0
CMS2_k127_1062400_4 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 454.0
CMS2_k127_1062400_5 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 428.0
CMS2_k127_1062400_6 Histidine kinase K10942 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 343.0
CMS2_k127_1062400_7 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000002356 243.0
CMS2_k127_1062400_8 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000000000000000000000000000000000000000000006177 237.0
CMS2_k127_1062400_9 COG0784 FOG CheY-like receiver K03413 - - 0.000000000000000000000000000000000000000000000000000000007403 199.0
CMS2_k127_106390_0 COG1194 A G-specific DNA glycosylase K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 416.0
CMS2_k127_106390_1 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 364.0
CMS2_k127_106390_2 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000000000000000000000000000000000000003732 226.0
CMS2_k127_106390_3 DJ-1/PfpI family K03152 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009100,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019538,GO:0022613,GO:0030091,GO:0033554,GO:0034599,GO:0036211,GO:0036524,GO:0036525,GO:0042026,GO:0042221,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 3.5.1.124 0.0000000000000000000000000000000000000000000000001764 183.0
CMS2_k127_106390_4 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000002578 141.0
CMS2_k127_106390_5 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000002466 142.0
CMS2_k127_106390_6 AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000005213 76.0
CMS2_k127_106390_7 - - - - 0.0000001354 54.0
CMS2_k127_1092288_0 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 559.0
CMS2_k127_1092288_1 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 385.0
CMS2_k127_1092288_3 sulfur carrier activity K04085 - - 0.0000000000000000000000001272 107.0
CMS2_k127_1092288_4 - - - - 0.000000000000000000002821 97.0
CMS2_k127_1092288_5 - - - - 0.0000000000002336 74.0
CMS2_k127_1092288_6 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000005997 70.0
CMS2_k127_1112733_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 2.933e-306 966.0
CMS2_k127_1112733_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.106e-281 872.0
CMS2_k127_1112733_10 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000396 164.0
CMS2_k127_1112733_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000006075 153.0
CMS2_k127_1112733_12 Glycosyl transferase, family 2 K12984 - - 0.00000000000000000000000000000000000000275 158.0
CMS2_k127_1112733_13 Divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000006238 132.0
CMS2_k127_1112733_14 FxsA cytoplasmic membrane protein K07113 - - 0.00000000000000000000000000000009042 129.0
CMS2_k127_1112733_15 transferase activity, transferring glycosyl groups K12989 - - 0.0000000000000000000000000000003397 131.0
CMS2_k127_1112733_16 Protein of unknown function (DUF3426) - - - 0.0000000000000000000000000000191 126.0
CMS2_k127_1112733_17 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000001457 102.0
CMS2_k127_1112733_18 Zinc-finger domain - - - 0.000000000000000000013 92.0
CMS2_k127_1112733_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 7.314e-240 749.0
CMS2_k127_1112733_3 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 4.025e-233 726.0
CMS2_k127_1112733_4 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 563.0
CMS2_k127_1112733_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 528.0
CMS2_k127_1112733_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 468.0
CMS2_k127_1112733_7 Ribosomal protein L11 methyltransferase K02687 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 343.0
CMS2_k127_1112733_8 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000009811 215.0
CMS2_k127_1112733_9 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000001093 192.0
CMS2_k127_1124943_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1217.0
CMS2_k127_1124943_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.297e-273 848.0
CMS2_k127_1124943_10 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000003884 257.0
CMS2_k127_1124943_11 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 GO:0001510,GO:0002128,GO:0002938,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008175,GO:0008757,GO:0009020,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0106050,GO:0140098,GO:0140101,GO:1901360 2.1.1.34 0.00000000000000000000000000000000000000000000000000000000000000000782 235.0
CMS2_k127_1124943_12 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000001228 226.0
CMS2_k127_1124943_13 COG2863 Cytochrome c553 - - - 0.000000000000000000000000000000000000000000000000000000000001034 216.0
CMS2_k127_1124943_14 COG2199 FOG GGDEF domain K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000004433 226.0
CMS2_k127_1124943_15 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.000000000000000000000000000000000000000000000000000000002738 205.0
CMS2_k127_1124943_16 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000000000000008186 204.0
CMS2_k127_1124943_17 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000005356 171.0
CMS2_k127_1124943_18 GGDEF domain - - - 0.0000000000000000000000000000000000000000001256 171.0
CMS2_k127_1124943_19 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000002838 117.0
CMS2_k127_1124943_2 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 5.747e-206 649.0
CMS2_k127_1124943_20 Protein of unknown function (DUF2782) - - - 0.0000000000002009 77.0
CMS2_k127_1124943_3 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 558.0
CMS2_k127_1124943_4 ResB-like family K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 569.0
CMS2_k127_1124943_5 Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) K06957 - 2.3.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 451.0
CMS2_k127_1124943_6 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 390.0
CMS2_k127_1124943_7 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 302.0
CMS2_k127_1124943_8 hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 296.0
CMS2_k127_1124943_9 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003179 278.0
CMS2_k127_1163691_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0 1056.0
CMS2_k127_1163691_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 5.335e-222 697.0
CMS2_k127_1163691_10 Thiopurine S-methyltransferase (TPMT) K00569 - 2.1.1.67 0.000000000000000000000000000000000000000000000000000000004906 206.0
CMS2_k127_1163691_11 Thioredoxin-like - - - 0.0000000000000000000000000005549 115.0
CMS2_k127_1163691_12 - - - - 0.000000000000000000000000105 109.0
CMS2_k127_1163691_13 - - - - 0.0000000000000000000000432 104.0
CMS2_k127_1163691_14 cell redox homeostasis K03671 - - 0.000000000000000000002289 102.0
CMS2_k127_1163691_16 Peptidase family M48 - - - 0.00002533 48.0
CMS2_k127_1163691_2 TIGRFAM amidase, hydantoinase carbamoylase K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 583.0
CMS2_k127_1163691_3 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 456.0
CMS2_k127_1163691_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 353.0
CMS2_k127_1163691_5 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 347.0
CMS2_k127_1163691_6 Isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 338.0
CMS2_k127_1163691_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 294.0
CMS2_k127_1163691_8 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K15461 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0004808,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 2.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007429 281.0
CMS2_k127_1163691_9 COG2202 FOG PAS PAC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002394 246.0
CMS2_k127_120586_0 ACT domain K00928 GO:0003674,GO:0003824,GO:0004072,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 533.0
CMS2_k127_120586_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 500.0
CMS2_k127_120586_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 327.0
CMS2_k127_1260411_0 carboxylase K01941 - 6.3.4.6 0.0 1668.0
CMS2_k127_1260411_1 glutamine synthetase K01915 - 6.3.1.2 1.979e-253 787.0
CMS2_k127_1260411_10 TIGRFAM Urea carboxylase-associated protein 1 K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 369.0
CMS2_k127_1260411_11 Xylose isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005553 347.0
CMS2_k127_1260411_12 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 342.0
CMS2_k127_1260411_13 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 321.0
CMS2_k127_1260411_14 AsnC family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000445 196.0
CMS2_k127_1260411_15 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.00000000000000000000000000000000000000000000000000001767 194.0
CMS2_k127_1260411_16 NikR C terminal nickel binding domain K07722 - - 0.0000000000000000000000000000000000000000000000000001042 189.0
CMS2_k127_1260411_17 Rhodanese Homology Domain - - - 0.000000000000000888 81.0
CMS2_k127_1260411_18 - - - - 0.00000004998 64.0
CMS2_k127_1260411_19 DNA-binding transcription factor activity - - - 0.0000002301 59.0
CMS2_k127_1260411_2 Amidase K01457 - 3.5.1.54 1.766e-218 692.0
CMS2_k127_1260411_3 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 4.605e-209 657.0
CMS2_k127_1260411_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 589.0
CMS2_k127_1260411_5 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 557.0
CMS2_k127_1260411_6 PFAM ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 503.0
CMS2_k127_1260411_7 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 496.0
CMS2_k127_1260411_8 NMT1/THI5 like K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 477.0
CMS2_k127_1260411_9 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007469 391.0
CMS2_k127_1263032_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1048.0
CMS2_k127_1263032_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 3.964e-212 665.0
CMS2_k127_1263032_10 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 375.0
CMS2_k127_1263032_11 Phosphorylates 6-deoxy-6-sulfo-D-fructose (SF) to 6- deoxy-6-sulfo-D-fructose 1-phosphate (SFP) K00846,K18478 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006066,GO:0006082,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0034308,GO:0042180,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044273,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0061594,GO:0061720,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901615,GO:1902776,GO:1902777 2.7.1.184,2.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 327.0
CMS2_k127_1263032_12 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 302.0
CMS2_k127_1263032_13 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000002952 261.0
CMS2_k127_1263032_14 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000001065 184.0
CMS2_k127_1263032_15 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000001681 173.0
CMS2_k127_1263032_16 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 GO:0000175,GO:0003674,GO:0003724,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008408,GO:0008997,GO:0009056,GO:0009057,GO:0009266,GO:0009409,GO:0009628,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016896,GO:0017111,GO:0019222,GO:0019439,GO:0034458,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000001722 161.0
CMS2_k127_1263032_17 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000008738 146.0
CMS2_k127_1263032_18 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 0.00000000000000000000000000000002936 126.0
CMS2_k127_1263032_19 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000006911 67.0
CMS2_k127_1263032_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006464,GO:0006468,GO:0006518,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006996,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018105,GO:0018193,GO:0018209,GO:0019001,GO:0019222,GO:0019538,GO:0019843,GO:0022411,GO:0030554,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0032790,GO:0032984,GO:0032988,GO:0034248,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0036211,GO:0036289,GO:0043021,GO:0043022,GO:0043023,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 529.0
CMS2_k127_1263032_3 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 522.0
CMS2_k127_1263032_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 520.0
CMS2_k127_1263032_5 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 481.0
CMS2_k127_1263032_6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 476.0
CMS2_k127_1263032_7 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 454.0
CMS2_k127_1263032_8 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 426.0
CMS2_k127_1263032_9 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 386.0
CMS2_k127_1317041_0 Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP) K00209 - 1.3.1.44,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 607.0
CMS2_k127_1317041_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 350.0
CMS2_k127_1317041_10 Globin - - - 0.000000000000000000000000000000000000000000000000000006867 194.0
CMS2_k127_1317041_11 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000005534 195.0
CMS2_k127_1317041_12 - - - - 0.0000000000000000000000000000002942 132.0
CMS2_k127_1317041_13 cold-shock protein K03704 - - 0.0000000000000000000000000000009113 122.0
CMS2_k127_1317041_14 - - - - 0.00000000000000000001799 94.0
CMS2_k127_1317041_15 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964 - 4.2.1.109 0.000000000005682 65.0
CMS2_k127_1317041_16 - - - - 0.0000000003735 64.0
CMS2_k127_1317041_2 Extradiol ring-cleavage dioxygenase, class III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 344.0
CMS2_k127_1317041_3 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 296.0
CMS2_k127_1317041_4 Histidine kinase K20974 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 312.0
CMS2_k127_1317041_5 Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 299.0
CMS2_k127_1317041_6 Domain of unknown function (DUF3413) K07014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000235 293.0
CMS2_k127_1317041_7 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008899 257.0
CMS2_k127_1317041_8 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.00000000000000000000000000000000000000000000000000000000000000000004512 235.0
CMS2_k127_1317041_9 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000004634 237.0
CMS2_k127_1543352_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 1.389e-276 861.0
CMS2_k127_1543352_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 7.636e-243 770.0
CMS2_k127_1543352_10 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005393 282.0
CMS2_k127_1543352_11 Bacterial lipid A biosynthesis acyltransferase K02560 - 2.3.1.243 0.0000000000000000000000000000000000000000000000000000000000000000000004997 249.0
CMS2_k127_1543352_12 Pfam Rhodanese-like - - - 0.00000000000000000000000000000000000000000000000000000000000000004139 224.0
CMS2_k127_1543352_13 NfeD-like C-terminal, partner-binding K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000001895 177.0
CMS2_k127_1543352_14 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000004992 184.0
CMS2_k127_1543352_15 E-Z type HEAT repeats - - - 0.0000000000000000000000000000000000000000001506 173.0
CMS2_k127_1543352_16 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000001114 151.0
CMS2_k127_1543352_17 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000012 138.0
CMS2_k127_1543352_18 Sporulation related domain - - - 0.00000000000000000000000000000000106 138.0
CMS2_k127_1543352_19 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0000000000000000000000000000009113 122.0
CMS2_k127_1543352_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 546.0
CMS2_k127_1543352_3 aminotransferase K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 497.0
CMS2_k127_1543352_4 Single cache domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 464.0
CMS2_k127_1543352_5 COG0330 Membrane protease subunits, stomatin prohibitin homologs - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000726 441.0
CMS2_k127_1543352_6 Belongs to the TtcA family K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 353.0
CMS2_k127_1543352_7 Fructosamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 334.0
CMS2_k127_1543352_8 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 323.0
CMS2_k127_1543352_9 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 296.0
CMS2_k127_1570171_0 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 484.0
CMS2_k127_1570171_1 DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 337.0
CMS2_k127_1570171_2 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 296.0
CMS2_k127_1570171_3 dihydrofolate reductase K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000004774 228.0
CMS2_k127_1570171_4 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.0000000000000000000005317 97.0
CMS2_k127_1579610_0 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 2.279e-225 711.0
CMS2_k127_1579610_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 433.0
CMS2_k127_1579610_10 Response regulator of the LytR AlgR family K08083 - - 0.000000000000000000002816 102.0
CMS2_k127_1579610_11 Protein of unknown function (DUF3622) - - - 0.000000000000001213 79.0
CMS2_k127_1579610_12 Polymer-forming cytoskeletal - - - 0.00000000001681 76.0
CMS2_k127_1579610_13 - - - - 0.0000001135 56.0
CMS2_k127_1579610_2 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 407.0
CMS2_k127_1579610_3 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 289.0
CMS2_k127_1579610_4 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000001453 240.0
CMS2_k127_1579610_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000001653 232.0
CMS2_k127_1579610_6 biosynthesis protein HemY K02498 - - 0.0000000000000000000000000000000000000000000000000000000001104 218.0
CMS2_k127_1579610_7 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000005274 207.0
CMS2_k127_1579610_8 enzyme of heme biosynthesis K02496,K13543 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000002603 158.0
CMS2_k127_1579610_9 Thioredoxin-like - - - 0.0000000000000000000000000002505 120.0
CMS2_k127_1584687_0 von Willebrand factor (vWF) type A domain K02448 - - 7.446e-218 696.0
CMS2_k127_1584687_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 607.0
CMS2_k127_1584687_10 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000005503 184.0
CMS2_k127_1584687_11 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000001458 170.0
CMS2_k127_1584687_12 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000435 167.0
CMS2_k127_1584687_13 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000009441 152.0
CMS2_k127_1584687_14 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000006703 113.0
CMS2_k127_1584687_15 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000226 116.0
CMS2_k127_1584687_16 diguanylate cyclase - - - 0.0000006137 57.0
CMS2_k127_1584687_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 512.0
CMS2_k127_1584687_3 Phosphate-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 505.0
CMS2_k127_1584687_4 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 455.0
CMS2_k127_1584687_5 signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 411.0
CMS2_k127_1584687_6 chemotaxis, protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 373.0
CMS2_k127_1584687_7 phosphate regulon transcriptional regulatory protein PhoB K07657 GO:0001098,GO:0001108,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0043254,GO:0044087,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 311.0
CMS2_k127_1584687_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000001139 235.0
CMS2_k127_1584687_9 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000003043 192.0
CMS2_k127_159558_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.111e-206 649.0
CMS2_k127_159558_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 514.0
CMS2_k127_159558_2 UBA THIF-type NAD FAD binding K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 321.0
CMS2_k127_159558_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001437 229.0
CMS2_k127_159558_4 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000005869 231.0
CMS2_k127_159558_5 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000004355 124.0
CMS2_k127_159558_6 HD domain K07315 - 3.1.3.3 0.00000000000000000000000000000463 134.0
CMS2_k127_159558_8 lyase activity - - - 0.0000000000001791 78.0
CMS2_k127_1603113_0 COG0514 Superfamily II DNA helicase K03654 - 3.6.4.12 9.164e-309 960.0
CMS2_k127_1603113_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.383e-271 848.0
CMS2_k127_1603113_2 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 2.208e-225 712.0
CMS2_k127_1603113_3 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 586.0
CMS2_k127_1603113_4 Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 448.0
CMS2_k127_1603113_5 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000001582 219.0
CMS2_k127_1603113_6 chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.0000000000000000000000000000000000000000000000004615 180.0
CMS2_k127_1603113_7 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 GO:0003674,GO:0003824,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016154,GO:0016740,GO:0016757,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.1,2.4.2.2 0.00000000000000000000000000000000000001258 145.0
CMS2_k127_1603113_8 cold-shock protein K03704 - - 0.0000000000000000000000000000008623 121.0
CMS2_k127_1647525_0 receptor K02014 - - 7.633e-205 660.0
CMS2_k127_1647525_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 598.0
CMS2_k127_1647525_2 Cobyrinic acid A,C-diamide K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 565.0
CMS2_k127_1647525_3 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 426.0
CMS2_k127_1647525_4 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 314.0
CMS2_k127_1647525_5 response regulator receiver K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004161 255.0
CMS2_k127_1647525_6 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000446 200.0
CMS2_k127_1647525_7 PFAM Rhodanese-like - - - 0.00000000000000000000000000000000000000000000000000006064 190.0
CMS2_k127_1647525_8 Iron-sulphur cluster biosynthesis - - - 0.0000000000000000000000000000002942 126.0
CMS2_k127_1647525_9 sequence-specific DNA binding K13280 - 3.4.21.89 0.0000000000000000000009754 100.0
CMS2_k127_1649425_0 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 416.0
CMS2_k127_1649425_1 Reductase C-terminal K00529,K21738 - 1.18.1.1,1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 387.0
CMS2_k127_1649425_2 transport system, permease component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 361.0
CMS2_k127_1649425_3 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 329.0
CMS2_k127_1649425_4 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 287.0
CMS2_k127_1649425_5 COG0725 ABC-type molybdate transport system, periplasmic component K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007507 277.0
CMS2_k127_1649425_6 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003179 249.0
CMS2_k127_1649425_7 Ferredoxin K04755 - - 0.000000000000000000000000000000000000000001011 159.0
CMS2_k127_1649425_8 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030312,GO:0030313,GO:0031975,GO:0043170,GO:0044462,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000761 111.0
CMS2_k127_1674200_0 subfamily IA, variant 3 K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000001407 251.0
CMS2_k127_1674200_1 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000005516 250.0
CMS2_k127_1674200_2 pfam nudix K08312 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001178 243.0
CMS2_k127_1674200_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000006527 222.0
CMS2_k127_1674200_4 metal cluster binding K06940 - - 0.000000000000000000000000000000000000000000000000004191 185.0
CMS2_k127_1706667_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 9.225e-211 661.0
CMS2_k127_1706667_1 COG0527 Aspartokinases K00928 GO:0003674,GO:0003824,GO:0004072,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019491,GO:0019752,GO:0032787,GO:0042399,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 1.862e-199 631.0
CMS2_k127_1706667_2 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000002049 206.0
CMS2_k127_1706667_3 Cupin 2, conserved barrel domain protein K06720 - 4.2.1.108 0.0000000000000000000000000000000000000000000000000000005335 196.0
CMS2_k127_1706667_4 PFAM regulatory protein, MarR - - - 0.0000000000000000000000000000000000000000000009838 171.0
CMS2_k127_1706667_5 L-2,4-diaminobutyric acid acetyltransferase K06718 - 2.3.1.178 0.00000000000000000000000000000000000000005057 157.0
CMS2_k127_1706667_6 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000009559 147.0
CMS2_k127_1706667_7 Cysteine-rich CWC - - - 0.000000000000005467 80.0
CMS2_k127_1706667_8 - - - - 0.00000000000005288 72.0
CMS2_k127_1735201_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.15e-219 687.0
CMS2_k127_1735201_1 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 3.03e-211 670.0
CMS2_k127_1735201_10 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 445.0
CMS2_k127_1735201_11 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 407.0
CMS2_k127_1735201_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008804 402.0
CMS2_k127_1735201_13 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 371.0
CMS2_k127_1735201_14 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 369.0
CMS2_k127_1735201_15 lipoprotein K07121 GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 355.0
CMS2_k127_1735201_16 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 332.0
CMS2_k127_1735201_17 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000001671 196.0
CMS2_k127_1735201_18 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000000431 190.0
CMS2_k127_1735201_19 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000003384 120.0
CMS2_k127_1735201_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 6.33e-204 644.0
CMS2_k127_1735201_20 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000001603 94.0
CMS2_k127_1735201_21 - - - - 0.000000000000001696 78.0
CMS2_k127_1735201_23 Protein of unknown function (DUF721) - - - 0.0000000002994 67.0
CMS2_k127_1735201_3 FAD linked oxidases, C-terminal domain K03777 - 1.1.5.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 607.0
CMS2_k127_1735201_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 557.0
CMS2_k127_1735201_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 557.0
CMS2_k127_1735201_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 487.0
CMS2_k127_1735201_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 479.0
CMS2_k127_1735201_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 469.0
CMS2_k127_1735201_9 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 435.0
CMS2_k127_1741807_0 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009815 579.0
CMS2_k127_1741807_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 496.0
CMS2_k127_1741807_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 302.0
CMS2_k127_1741807_3 TIGRFAM channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002233 252.0
CMS2_k127_1741807_4 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000005085 143.0
CMS2_k127_1741807_5 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000000000000000000000000000005752 128.0
CMS2_k127_1741807_6 DNA-binding protein VF530 - - - 0.000000000000000000000000008018 112.0
CMS2_k127_1741807_7 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.00000000000000000000000126 103.0
CMS2_k127_1748031_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1461.0
CMS2_k127_1748031_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 508.0
CMS2_k127_1748031_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 486.0
CMS2_k127_1748031_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 418.0
CMS2_k127_1748031_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000001783 230.0
CMS2_k127_1748031_5 Rhodanese Homology Domain - - - 0.0000000002777 69.0
CMS2_k127_1866934_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1269.0
CMS2_k127_1866934_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003919 462.0
CMS2_k127_1866934_2 ApbE family K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 311.0
CMS2_k127_1866934_3 Protein of unknown function (DUF3570) - - - 0.000000000000000000000000000000000000000000000000000000000001638 224.0
CMS2_k127_1866934_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000001568 181.0
CMS2_k127_1866934_5 Thioredoxin-like - - - 0.0000000000000000000000000000000000002932 149.0
CMS2_k127_1866934_6 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.000000000000000000000000000000006268 132.0
CMS2_k127_1866934_9 Domain of unknown function (DUF4266) - - - 0.00000000000001971 76.0
CMS2_k127_1887553_0 Heat shock 70 kDa protein K04043 - - 5.908e-283 874.0
CMS2_k127_1887553_1 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 594.0
CMS2_k127_1887553_10 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000005927 92.0
CMS2_k127_1887553_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 525.0
CMS2_k127_1887553_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 375.0
CMS2_k127_1887553_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 300.0
CMS2_k127_1887553_5 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000001528 236.0
CMS2_k127_1887553_6 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000004107 213.0
CMS2_k127_1887553_7 Cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000000000000001588 203.0
CMS2_k127_1887553_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000003909 189.0
CMS2_k127_1887553_9 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000000000000000000000006798 132.0
CMS2_k127_1905603_0 Multi-copper - - - 1.884e-281 878.0
CMS2_k127_1905603_1 ATP-grasp domain K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 463.0
CMS2_k127_1905603_2 PFAM copper resistance B precursor K07233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002525 254.0
CMS2_k127_1905603_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000004162 241.0
CMS2_k127_1905603_4 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.0000000000000000000000000000000000000000000000001053 184.0
CMS2_k127_1905603_5 Predicted membrane protein (DUF2231) - - - 0.0000000000000000000000000000000000000000003394 165.0
CMS2_k127_1905603_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000005455 163.0
CMS2_k127_1922956_0 EcoEI R protein C-terminal K01153 - 3.1.21.3 0.0 1121.0
CMS2_k127_1922956_1 HsdM N-terminal domain K03427 - 2.1.1.72 4.852e-230 720.0
CMS2_k127_1922956_10 Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - - 0.000000000000000000000000000000000000000000000000000000000002702 210.0
CMS2_k127_1922956_11 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000005617 183.0
CMS2_k127_1922956_12 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000008879 166.0
CMS2_k127_1922956_13 - - - - 0.00000000000000005094 83.0
CMS2_k127_1922956_2 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 7.621e-196 618.0
CMS2_k127_1922956_3 PFAM Restriction endonuclease, type I, S subunit, EcoBI K01154 - 3.1.21.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 552.0
CMS2_k127_1922956_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 481.0
CMS2_k127_1922956_5 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 455.0
CMS2_k127_1922956_6 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 449.0
CMS2_k127_1922956_7 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 388.0
CMS2_k127_1922956_8 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 325.0
CMS2_k127_1922956_9 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000381 265.0
CMS2_k127_2001897_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 522.0
CMS2_k127_2001897_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 405.0
CMS2_k127_2001897_10 transmembrane signaling receptor activity - - - 0.00000000007479 70.0
CMS2_k127_2001897_2 PFAM Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 400.0
CMS2_k127_2001897_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 394.0
CMS2_k127_2001897_4 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 342.0
CMS2_k127_2001897_5 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003817 277.0
CMS2_k127_2001897_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002508 270.0
CMS2_k127_2001897_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009762 264.0
CMS2_k127_2001897_8 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000001425 226.0
CMS2_k127_2001897_9 DUF218 domain - - - 0.00000000000000000000000000000000002052 146.0
CMS2_k127_2028873_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1049.0
CMS2_k127_2028873_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 3.367e-269 841.0
CMS2_k127_2028873_10 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000896 224.0
CMS2_k127_2028873_11 HD domain - - - 0.000000000000000000000000000000000000000000000000000007955 204.0
CMS2_k127_2028873_12 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000008947 183.0
CMS2_k127_2028873_13 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000002165 137.0
CMS2_k127_2028873_14 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000006084 124.0
CMS2_k127_2028873_15 SH3 domain K07184 - - 0.00000000000000000000000000009059 125.0
CMS2_k127_2028873_16 - - - - 0.000000001415 61.0
CMS2_k127_2028873_2 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 9.982e-224 703.0
CMS2_k127_2028873_3 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008527 544.0
CMS2_k127_2028873_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 474.0
CMS2_k127_2028873_5 COG1131 ABC-type multidrug transport system, ATPase component K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 424.0
CMS2_k127_2028873_6 Two component signalling adaptor domain K03415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 397.0
CMS2_k127_2028873_7 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 359.0
CMS2_k127_2028873_8 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 355.0
CMS2_k127_2028873_9 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004093 284.0
CMS2_k127_204813_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0000166,GO:0003674,GO:0003824,GO:0004362,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071949,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.7 6.239e-215 676.0
CMS2_k127_204813_1 FIST C domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 420.0
CMS2_k127_204813_10 Protein of unknown function (DUF2796) - - - 0.0000000000000000000000000000000000001939 148.0
CMS2_k127_204813_11 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000000000000000000000000003104 147.0
CMS2_k127_204813_12 MacB-like periplasmic core domain K02004 - - 0.00000000002014 68.0
CMS2_k127_204813_2 Glutaredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007622 400.0
CMS2_k127_204813_3 Transcriptional regulator K04761 GO:0000976,GO:0000984,GO:0000986,GO:0000987,GO:0001017,GO:0001067,GO:0001130,GO:0001131,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0033554,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0051409,GO:0051716,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 313.0
CMS2_k127_204813_4 pfam abc K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003237 281.0
CMS2_k127_204813_5 2OG-Fe(II) oxygenase K07394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003771 252.0
CMS2_k127_204813_6 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000002984 232.0
CMS2_k127_204813_7 COG0642 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000004257 219.0
CMS2_k127_204813_8 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000001366 162.0
CMS2_k127_204813_9 phosphinothricin N-acetyltransferase activity K03830 - - 0.0000000000000000000000000000000000001576 147.0
CMS2_k127_2049047_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576 - - 5.043e-252 783.0
CMS2_k127_2049047_1 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 524.0
CMS2_k127_2049047_2 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 469.0
CMS2_k127_2049047_3 TIGRFAM Nitrate transport ATP-binding K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 435.0
CMS2_k127_2049047_4 phenylacetate-CoA ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 289.0
CMS2_k127_2049047_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003761 263.0
CMS2_k127_2049047_6 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0043906,GO:0043907,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000006711 199.0
CMS2_k127_2049047_7 response regulator K07183 - - 0.000000000000000000000000000000000000000000009034 169.0
CMS2_k127_2049047_8 dihydrofolate reductase K00287 - 1.5.1.3 0.000000000000000000000000000000000003534 139.0
CMS2_k127_2049047_9 protein conserved in bacteria - - - 0.0000000000000007524 83.0
CMS2_k127_2077804_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1588.0
CMS2_k127_2077804_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 470.0
CMS2_k127_2077804_10 TIGRFAM formate dehydrogenase region TAT target - - - 0.0002035 46.0
CMS2_k127_2077804_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 446.0
CMS2_k127_2077804_3 Formate dehydrogenase N, transmembrane K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 377.0
CMS2_k127_2077804_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 355.0
CMS2_k127_2077804_5 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 350.0
CMS2_k127_2077804_6 component of anaerobic dehydrogenases - - - 0.000000000000000000000000000000000000000000000000001049 190.0
CMS2_k127_2077804_7 Protein of unknown function (DUF3305) - - - 0.0000000000000000000000000000000001796 139.0
CMS2_k127_2077804_8 4Fe-4S binding domain - - - 0.0000000000000000000000001882 112.0
CMS2_k127_2089678_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 382.0
CMS2_k127_2089678_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 GO:0000049,GO:0000166,GO:0002943,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010181,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0032553,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 306.0
CMS2_k127_2089678_2 peptidyl-tyrosine sulfation - - - 0.000000000213 72.0
CMS2_k127_2089807_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 3.114e-304 940.0
CMS2_k127_2089807_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 GO:0000166,GO:0001716,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008734,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0015922,GO:0016491,GO:0016638,GO:0016641,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044318,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605 1.4.3.16 2.157e-233 732.0
CMS2_k127_2089807_10 succinate dehydrogenase activity K00242 GO:0000104,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017004,GO:0017144,GO:0019752,GO:0020037,GO:0022607,GO:0022900,GO:0032991,GO:0034622,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0065003,GO:0070469,GO:0070470,GO:0071704,GO:0071840,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901363,GO:1902494,GO:1990204 - 0.0000000000000005954 81.0
CMS2_k127_2089807_11 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000001113 78.0
CMS2_k127_2089807_12 COG3086 Positive regulator of sigma E activity K03803 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.0000000000001163 79.0
CMS2_k127_2089807_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 500.0
CMS2_k127_2089807_3 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 385.0
CMS2_k127_2089807_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002863 280.0
CMS2_k127_2089807_5 PFAM MucB RseB K03598 - - 0.0000000000000000000000000000000000000000000000000000009523 204.0
CMS2_k127_2089807_6 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000003529 177.0
CMS2_k127_2089807_7 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000001168 120.0
CMS2_k127_2089807_8 Glutaredoxin-like protein - - - 0.0000000000000000000003605 98.0
CMS2_k127_2089807_9 PFAM Anti sigma-E protein RseA K03597 - - 0.00000000000000000004365 97.0
CMS2_k127_2134731_0 serine-type endopeptidase activity K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 460.0
CMS2_k127_2134731_1 PFAM Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 440.0
CMS2_k127_2134731_10 YcgL domain-containing protein K09902 - - 0.0000000000001659 74.0
CMS2_k127_2134731_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 429.0
CMS2_k127_2134731_3 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 415.0
CMS2_k127_2134731_4 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 294.0
CMS2_k127_2134731_5 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000008965 158.0
CMS2_k127_2134731_6 PFAM Uncharacterised protein family (UPF0153) K18475 - - 0.00000000000000000000000000000001987 142.0
CMS2_k127_2134731_7 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000002969 114.0
CMS2_k127_2134731_8 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.000000000000000000005138 101.0
CMS2_k127_2134731_9 ThiS family K03154 - - 0.000000000000000007208 85.0
CMS2_k127_2148395_0 Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005484 275.0
CMS2_k127_2148395_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009029 271.0
CMS2_k127_2148395_2 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000003532 148.0
CMS2_k127_2148395_3 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000004008 136.0
CMS2_k127_2148395_4 Belongs to the frataxin family K06202 - - 0.0000000000000000000000000001574 119.0
CMS2_k127_2208233_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1070.0
CMS2_k127_2208233_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1015.0
CMS2_k127_2208233_10 of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 312.0
CMS2_k127_2208233_11 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 297.0
CMS2_k127_2208233_12 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000137 283.0
CMS2_k127_2208233_13 Peroxiredoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000001359 218.0
CMS2_k127_2208233_14 ACT domain K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000001249 201.0
CMS2_k127_2208233_15 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes K03800 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.000000000000000000000000000000000000000002033 160.0
CMS2_k127_2208233_16 - - - - 0.000000000000000000000002551 106.0
CMS2_k127_2208233_17 COG1716 FOG FHA domain - - - 0.0000000000000000002056 93.0
CMS2_k127_2208233_18 NlpB/DapX lipoprotein K07287 - - 0.00000001906 63.0
CMS2_k127_2208233_2 SMART Nucleotide binding protein, PINc K07175 - - 4.424e-204 644.0
CMS2_k127_2208233_3 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 557.0
CMS2_k127_2208233_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 463.0
CMS2_k127_2208233_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 440.0
CMS2_k127_2208233_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 431.0
CMS2_k127_2208233_7 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 421.0
CMS2_k127_2208233_8 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016874,GO:0016879,GO:0016881,GO:0044424,GO:0044444,GO:0044464 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 376.0
CMS2_k127_2208233_9 AI-2E family transporter K03548 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 381.0
CMS2_k127_2219738_0 cation transport ATPase K01533 - 3.6.3.4 2.071e-306 959.0
CMS2_k127_2219738_1 COG0405 Gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 9.554e-219 692.0
CMS2_k127_2219738_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 361.0
CMS2_k127_2219738_11 ATPase involved in cell division K09812 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 313.0
CMS2_k127_2219738_12 Part of the ABC transporter FtsEX involved in cellular division K09811 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 321.0
CMS2_k127_2219738_13 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000000000000000000002114 226.0
CMS2_k127_2219738_14 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000005278 220.0
CMS2_k127_2219738_15 FixH - - - 0.0000000000000000000000000000000000000000000000000000000000000112 224.0
CMS2_k127_2219738_16 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000006399 151.0
CMS2_k127_2219738_17 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000000008316 129.0
CMS2_k127_2219738_18 Cytochrome oxidase maturation protein - - - 0.0000000000000000001096 93.0
CMS2_k127_2219738_19 Cbb3-type cytochrome oxidase component FixQ - - - 0.000000001218 61.0
CMS2_k127_2219738_2 TIGRFAM cytochrome c oxidase accessory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 595.0
CMS2_k127_2219738_3 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 569.0
CMS2_k127_2219738_4 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 557.0
CMS2_k127_2219738_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 565.0
CMS2_k127_2219738_6 Peptidase M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 450.0
CMS2_k127_2219738_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 430.0
CMS2_k127_2219738_8 TIGRFAM cytochrome c oxidase, cbb3-type, subunit II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 401.0
CMS2_k127_2219738_9 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 397.0
CMS2_k127_2237520_0 Fumarate reductase flavoprotein C-term - - - 1.147e-237 735.0
CMS2_k127_2237520_1 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 6.62e-226 703.0
CMS2_k127_2237520_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 376.0
CMS2_k127_2237520_3 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 309.0
CMS2_k127_2252006_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 1.64e-199 627.0
CMS2_k127_2252006_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 564.0
CMS2_k127_2252006_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 533.0
CMS2_k127_2252006_3 Chloride channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 505.0
CMS2_k127_2252006_4 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 362.0
CMS2_k127_2252006_5 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006266 359.0
CMS2_k127_2252006_6 Iron--sulfur cluster insertion protein erpA K15724 - - 0.0000000000000000000000000000000000000000000000000000002846 195.0
CMS2_k127_2252006_7 Glutathione peroxidase - - - 0.0000000000000000000000000000000000000000000000000747 183.0
CMS2_k127_2252006_8 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000000000008883 172.0
CMS2_k127_2252006_9 - - - - 0.00000000000000000000000000003466 126.0
CMS2_k127_2252477_0 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 1.28e-285 887.0
CMS2_k127_2252477_1 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 6.37e-239 746.0
CMS2_k127_2252477_10 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009087 342.0
CMS2_k127_2252477_11 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000004858 230.0
CMS2_k127_2252477_12 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000001891 196.0
CMS2_k127_2252477_13 Response regulator receiver domain K03413 - - 0.000000000000000000000000000000000000003251 149.0
CMS2_k127_2252477_14 acetyltransferase - - - 0.0000000000000000000000000000000000761 139.0
CMS2_k127_2252477_15 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000003189 127.0
CMS2_k127_2252477_16 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000005668 110.0
CMS2_k127_2252477_17 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000003198 98.0
CMS2_k127_2252477_2 protease with the C-terminal PDZ domain - - - 2.441e-213 679.0
CMS2_k127_2252477_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 5.461e-208 653.0
CMS2_k127_2252477_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 520.0
CMS2_k127_2252477_5 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 474.0
CMS2_k127_2252477_6 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 441.0
CMS2_k127_2252477_7 Anthranilate synthase component I K01657,K01665 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 441.0
CMS2_k127_2252477_8 malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 403.0
CMS2_k127_2252477_9 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 351.0
CMS2_k127_2290129_0 glutamate--cysteine ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009711 534.0
CMS2_k127_2290129_1 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 494.0
CMS2_k127_2290129_10 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 352.0
CMS2_k127_2290129_11 TIGRFAM Lytic murein transglycosylase B K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 351.0
CMS2_k127_2290129_12 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 344.0
CMS2_k127_2290129_13 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 323.0
CMS2_k127_2290129_14 Peptidoglycan polymerase that is essential for cell wall elongation K05837 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 310.0
CMS2_k127_2290129_15 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 302.0
CMS2_k127_2290129_16 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005183 269.0
CMS2_k127_2290129_17 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000008897 254.0
CMS2_k127_2290129_18 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000004916 238.0
CMS2_k127_2290129_19 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000005263 230.0
CMS2_k127_2290129_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 467.0
CMS2_k127_2290129_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000002383 233.0
CMS2_k127_2290129_21 - - - - 0.00000000000000000000000000000000000000000000000000000000001111 211.0
CMS2_k127_2290129_22 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000004279 216.0
CMS2_k127_2290129_23 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000001223 228.0
CMS2_k127_2290129_24 PFAM ApaG domain protein K06195 - - 0.00000000000000000000000000000000000000000000002206 173.0
CMS2_k127_2290129_25 Tetratricopeptide repeat - - - 0.000000000000000000000000002983 124.0
CMS2_k127_2290129_26 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000008546 109.0
CMS2_k127_2290129_28 Belongs to the UPF0250 family - - - 0.0000000000000000000003219 102.0
CMS2_k127_2290129_29 Late competence development protein ComFB - - - 0.000000000001458 71.0
CMS2_k127_2290129_3 Pyridoxal phosphate biosynthetic protein PdxA K00097 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 432.0
CMS2_k127_2290129_31 LysM domain K21687 - - 0.0000000001823 74.0
CMS2_k127_2290129_33 IS30 family - - - 0.0000002234 52.0
CMS2_k127_2290129_4 Belongs to the peptidase S11 family K07258 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 404.0
CMS2_k127_2290129_5 PFAM Succinylglutamate desuccinylase Aspartoacylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 400.0
CMS2_k127_2290129_6 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 379.0
CMS2_k127_2290129_7 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 368.0
CMS2_k127_2290129_8 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 362.0
CMS2_k127_2290129_9 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 367.0
CMS2_k127_230111_0 Domain of unknown function (DUF3400) - - - 0.0 1791.0
CMS2_k127_230111_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 499.0
CMS2_k127_230111_10 X-Pro dipeptidyl-peptidase (S15 family) K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000004865 228.0
CMS2_k127_230111_11 Redox protein regulator of disulfide bond formation K07397 - - 0.000000000000000000000000000000000000000000000000000000000000001848 220.0
CMS2_k127_230111_12 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000000000000000000002681 221.0
CMS2_k127_230111_13 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000009019 205.0
CMS2_k127_230111_14 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000001946 192.0
CMS2_k127_230111_15 Haem-degrading - - - 0.000000000000000000000000000000000000000000000001732 180.0
CMS2_k127_230111_16 ferredoxin - - - 0.0000000000000000000000000000000000000000000005066 168.0
CMS2_k127_230111_17 membrane - - - 0.00000000000000000000000000000000007861 137.0
CMS2_k127_230111_18 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.0000000000000000000000000000003381 126.0
CMS2_k127_230111_19 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000000000009378 120.0
CMS2_k127_230111_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 428.0
CMS2_k127_230111_20 DsrC like protein - - - 0.00000000000000000001761 95.0
CMS2_k127_230111_3 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 357.0
CMS2_k127_230111_4 drug resistance transporter Bcr CflA subfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 344.0
CMS2_k127_230111_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 343.0
CMS2_k127_230111_6 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 323.0
CMS2_k127_230111_7 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 322.0
CMS2_k127_230111_8 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 284.0
CMS2_k127_230111_9 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001404 239.0
CMS2_k127_2321859_0 associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 594.0
CMS2_k127_2321859_1 Putative metallopeptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 551.0
CMS2_k127_2321859_10 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.00000000000001422 78.0
CMS2_k127_2321859_2 PFAM Glycosyl transferase family, a b domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 443.0
CMS2_k127_2321859_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 344.0
CMS2_k127_2321859_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 335.0
CMS2_k127_2321859_5 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 318.0
CMS2_k127_2321859_6 Sel1-like repeats. K07126 - - 0.000000000000000000000000000000000000000000000000000000001213 203.0
CMS2_k127_2321859_7 - - - - 0.000000000000000000000000000000000000122 148.0
CMS2_k127_2321859_8 PFAM response regulator receiver - - - 0.0000000000000000000007818 99.0
CMS2_k127_2321859_9 - - - - 0.00000000000000000008103 91.0
CMS2_k127_2375448_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 536.0
CMS2_k127_2375448_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 341.0
CMS2_k127_2375448_2 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 303.0
CMS2_k127_2375448_3 COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950 GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 2.7.6.3 0.000000000000000000000000000000000000000000000000005293 186.0
CMS2_k127_2375448_4 COG1858 Cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000005197 179.0
CMS2_k127_2375448_5 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000008733 119.0
CMS2_k127_2375448_6 Cytochrome c K00406,K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000001088 88.0
CMS2_k127_2375448_7 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000003939 58.0
CMS2_k127_2390256_0 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 472.0
CMS2_k127_2390256_1 Belongs to the agmatine deiminase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 356.0
CMS2_k127_2390256_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000009465 238.0
CMS2_k127_2390256_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000001051 213.0
CMS2_k127_2390256_4 Protein of unknown function (DUF2892) - - - 0.0000000000004933 70.0
CMS2_k127_2390256_5 Rhodanese Homology Domain - - - 0.0000000001017 64.0
CMS2_k127_2415085_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 1.006e-312 975.0
CMS2_k127_2443085_0 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 419.0
CMS2_k127_2443085_1 enzyme of heme biosynthesis K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 297.0
CMS2_k127_2443085_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005758 284.0
CMS2_k127_2443085_3 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000002384 237.0
CMS2_k127_2503631_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 5.061e-230 727.0
CMS2_k127_2503631_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 364.0
CMS2_k127_2503631_2 DNA-J related protein - - - 0.000000000000000000000000000000001476 137.0
CMS2_k127_2503631_3 Histidine Phosphotransfer domain K20976 - - 0.000000002297 63.0
CMS2_k127_2568316_0 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 5.403e-222 698.0
CMS2_k127_2568316_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 565.0
CMS2_k127_2568316_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00651 - 2.3.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 531.0
CMS2_k127_2568316_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000006528 200.0
CMS2_k127_2568316_4 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000005117 192.0
CMS2_k127_2568316_5 SprT homologues. K02742 - - 0.000000000000000000000000000000000000000001462 162.0
CMS2_k127_2586953_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 3.214e-290 911.0
CMS2_k127_2586953_1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 286.0
CMS2_k127_2605874_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 GO:0003674,GO:0003824,GO:0004641,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 515.0
CMS2_k127_2605874_1 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 358.0
CMS2_k127_2605874_10 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000002567 217.0
CMS2_k127_2605874_11 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000000002661 215.0
CMS2_k127_2605874_12 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000001335 231.0
CMS2_k127_2605874_13 Phosphoesterase K07095 - - 0.000000000000000000000000000000000000000000000000000000007461 203.0
CMS2_k127_2605874_14 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000007707 212.0
CMS2_k127_2605874_15 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000005836 189.0
CMS2_k127_2605874_16 Uncharacterized protein conserved in bacteria (DUF2066) K09938 - - 0.000000000000000000000000000000000000000000000001773 187.0
CMS2_k127_2605874_17 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000002892 176.0
CMS2_k127_2605874_18 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000001516 168.0
CMS2_k127_2605874_19 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000001054 159.0
CMS2_k127_2605874_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 350.0
CMS2_k127_2605874_20 LysM domain - - - 0.0000000000000000000000000000000000000741 147.0
CMS2_k127_2605874_21 PFAM phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000001963 125.0
CMS2_k127_2605874_22 acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000003301 98.0
CMS2_k127_2605874_23 Predicted membrane protein (DUF2069) - - - 0.00000000000000000000166 101.0
CMS2_k127_2605874_24 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0004736 51.0
CMS2_k127_2605874_3 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000008159 267.0
CMS2_k127_2605874_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001925 256.0
CMS2_k127_2605874_5 beta-fructofuranosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000933 258.0
CMS2_k127_2605874_6 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002805 246.0
CMS2_k127_2605874_7 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002385 233.0
CMS2_k127_2605874_8 Belongs to the DnaA family. HdA subfamily K10763 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008156,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030174,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:2000104,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000000001244 228.0
CMS2_k127_2605874_9 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000002726 234.0
CMS2_k127_2634521_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 1.825e-254 792.0
CMS2_k127_2634521_1 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 1.756e-222 694.0
CMS2_k127_2634521_10 PAS fold-4 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 412.0
CMS2_k127_2634521_11 PFAM histidine kinase, HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 382.0
CMS2_k127_2634521_12 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 354.0
CMS2_k127_2634521_13 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 334.0
CMS2_k127_2634521_14 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 299.0
CMS2_k127_2634521_15 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 287.0
CMS2_k127_2634521_16 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001845 270.0
CMS2_k127_2634521_17 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001876 256.0
CMS2_k127_2634521_18 peptidase K06194 - - 0.00000000000000000000000000000000000000000000000000000000006992 213.0
CMS2_k127_2634521_19 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000002155 184.0
CMS2_k127_2634521_2 PFAM Chemotaxis methyl-accepting receptor, signalling K03406 - - 1.351e-220 709.0
CMS2_k127_2634521_20 Smr protein - - - 0.0000000000000000000000000000000000000000001073 166.0
CMS2_k127_2634521_21 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301 - 0.0000000000000000000003955 98.0
CMS2_k127_2634521_22 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000124 98.0
CMS2_k127_2634521_23 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0000000000001909 70.0
CMS2_k127_2634521_3 homoserine dehydrogenase K00003 - 1.1.1.3 8.459e-212 665.0
CMS2_k127_2634521_4 DHH family K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 3.217e-207 660.0
CMS2_k127_2634521_5 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 5.047e-201 629.0
CMS2_k127_2634521_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 4.231e-200 630.0
CMS2_k127_2634521_7 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 543.0
CMS2_k127_2634521_8 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 451.0
CMS2_k127_2634521_9 RNA polymerase sigma K03087 GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 421.0
CMS2_k127_2653226_0 cobalamin-transporting ATPase activity K16092 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 399.0
CMS2_k127_2653226_1 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000002402 236.0
CMS2_k127_2653226_2 abc-type fe3 -hydroxamate transport system, periplasmic component K02016,K21701 - - 0.00000000000000000000000000000000000000000000000003655 184.0
CMS2_k127_2653226_3 TIGRFAM TonB family protein K03832 - - 0.0001961 51.0
CMS2_k127_2674756_0 lysine 2,3-aminomutase activity - - - 1.872e-209 666.0
CMS2_k127_2674756_1 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 580.0
CMS2_k127_2674756_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 530.0
CMS2_k127_2674756_3 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 399.0
CMS2_k127_2674756_4 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 400.0
CMS2_k127_2674756_5 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 390.0
CMS2_k127_2674756_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 326.0
CMS2_k127_2674756_7 SMART Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 292.0
CMS2_k127_2674756_8 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000003904 68.0
CMS2_k127_2746945_0 Proton-conducting membrane transporter K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 608.0
CMS2_k127_2746945_1 Proton-conducting membrane transporter K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 584.0
CMS2_k127_2746945_2 Proton-conducting membrane transporter K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 554.0
CMS2_k127_2746945_3 Domain of unknown function (DUF4040) K05566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 371.0
CMS2_k127_2746945_4 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006271 243.0
CMS2_k127_2746945_5 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.0000000000000000000000000000000000000000000008779 168.0
CMS2_k127_2746945_6 Na+/H+ ion antiporter subunit K05569 - - 0.00000000000000000000000000000000002346 139.0
CMS2_k127_2746945_7 - - - - 0.0000000000000000000000004388 106.0
CMS2_k127_2746945_8 MnhF PhaF family monovalent cation proton antiporter K05570 - - 0.000000000000000000000003211 106.0
CMS2_k127_2746945_9 Na+/H+ antiporter subunit K05571 - - 0.00000000000000000000002089 102.0
CMS2_k127_2785514_0 HELICc2 K03722 GO:0003674,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:1901360 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 389.0
CMS2_k127_2785514_1 Belongs to the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002918 268.0
CMS2_k127_2785514_2 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000000001878 240.0
CMS2_k127_2785514_3 protein histidine kinase activity K11959,K19694 - - 0.00000000000000000000000000000000000000000000000000000000000000005671 241.0
CMS2_k127_2799834_0 DNA helicase K03657 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006289,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017116,GO:0022607,GO:0031297,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0042802,GO:0043142,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0045005,GO:0046483,GO:0050896,GO:0051259,GO:0051260,GO:0051276,GO:0051716,GO:0065003,GO:0070035,GO:0070581,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 3.149e-307 957.0
CMS2_k127_2799834_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 545.0
CMS2_k127_2799834_10 Propeptide PepSY amd peptidase M4 - - - 0.00000000000525 70.0
CMS2_k127_2799834_2 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 290.0
CMS2_k127_2799834_3 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001584 289.0
CMS2_k127_2799834_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003182 292.0
CMS2_k127_2799834_5 PFAM response regulator receiver, transcriptional regulator domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002401 238.0
CMS2_k127_2799834_6 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000003411 215.0
CMS2_k127_2799834_7 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000002005 184.0
CMS2_k127_2799834_8 Dihaem cytochrome c - - - 0.00000000000000000000000000000000000000000000002349 176.0
CMS2_k127_2799834_9 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000001042 136.0
CMS2_k127_2847724_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 GO:0003674,GO:0003824,GO:0004015,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.6.1.62 1.328e-196 622.0
CMS2_k127_2847724_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 391.0
CMS2_k127_2847724_10 response regulator K13246 - 3.1.4.52 0.0000000000000000000000000000000000000000002821 168.0
CMS2_k127_2847724_11 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000001303 153.0
CMS2_k127_2847724_12 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000002377 127.0
CMS2_k127_2847724_13 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues - - - 0.00006545 55.0
CMS2_k127_2847724_2 Bacterial transferase hexapeptide (six repeats) K18234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 301.0
CMS2_k127_2847724_3 ggdef domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 289.0
CMS2_k127_2847724_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001197 227.0
CMS2_k127_2847724_5 Uncharacterized protein family UPF0029 K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000191 209.0
CMS2_k127_2847724_6 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000008491 197.0
CMS2_k127_2847724_7 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000001051 172.0
CMS2_k127_2847724_8 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000003056 166.0
CMS2_k127_2847724_9 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000154 181.0
CMS2_k127_2895244_0 reductase, alpha subunit K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 603.0
CMS2_k127_2895244_1 sulphate transporter K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000791 612.0
CMS2_k127_2895244_2 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 415.0
CMS2_k127_2895244_3 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001571 251.0
CMS2_k127_2895244_4 Histidine triad (Hit) protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001001 244.0
CMS2_k127_2895244_5 - - - - 0.00000000000000000000000000000000000000000000000000000000009131 206.0
CMS2_k127_2895244_7 - - - - 0.00000000000000001188 83.0
CMS2_k127_2895323_0 Extracellular solute-binding protein, family 5 K02035 - - 5.4e-268 837.0
CMS2_k127_2895323_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 597.0
CMS2_k127_2895323_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 595.0
CMS2_k127_2895323_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 428.0
CMS2_k127_2895323_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 391.0
CMS2_k127_2895323_5 peptidylprolyl isomerase K03770 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0008150,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0061077,GO:0071575,GO:0071944,GO:0098552 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000001848 236.0
CMS2_k127_2959464_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.708e-251 794.0
CMS2_k127_2959464_1 chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 534.0
CMS2_k127_2959464_2 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 455.0
CMS2_k127_2959464_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 368.0
CMS2_k127_2959464_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000787 271.0
CMS2_k127_2959464_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001139 239.0
CMS2_k127_2959464_6 PFAM Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000009375 199.0
CMS2_k127_2959464_7 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000002086 205.0
CMS2_k127_2972914_0 SAF K01654,K15898 - 2.5.1.56,2.5.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 559.0
CMS2_k127_2972914_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 477.0
CMS2_k127_2972914_10 Rod binding protein K02395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001362 259.0
CMS2_k127_2972914_11 Protein of unknown function DUF115 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001801 263.0
CMS2_k127_2972914_12 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000000000000000000000000000000000000000002652 195.0
CMS2_k127_2972914_13 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.00000000000000000000000000000000000000000000000000003379 195.0
CMS2_k127_2972914_14 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000001465 171.0
CMS2_k127_2972914_15 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.0000000000000000000000000000000000000000000808 162.0
CMS2_k127_2972914_17 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00002308 50.0
CMS2_k127_2972914_2 TIGRFAM Flagellar hook-associated protein, FlgK K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 471.0
CMS2_k127_2972914_3 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 381.0
CMS2_k127_2972914_4 basal body rod protein K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 362.0
CMS2_k127_2972914_5 basal body rod protein K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 371.0
CMS2_k127_2972914_6 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 319.0
CMS2_k127_2972914_7 TIGRFAM Flagellar hook-associated protein 3 K02397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 316.0
CMS2_k127_2972914_8 TIGRFAM flagellar basal-body rod protein FlgF K02391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002213 285.0
CMS2_k127_2972914_9 Pseudaminic acid biosynthesis-associated methylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004169 265.0
CMS2_k127_2987325_0 FAD-dependent dehydrogenases K07137 - - 5.816e-281 871.0
CMS2_k127_2987325_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 479.0
CMS2_k127_2987325_10 - - - - 0.0000000000000000001714 94.0
CMS2_k127_2987325_11 acetyltransferase - - - 0.000000000000004835 89.0
CMS2_k127_2987325_2 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009545 305.0
CMS2_k127_2987325_3 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000000002861 229.0
CMS2_k127_2987325_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000067 212.0
CMS2_k127_2987325_5 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000001796 184.0
CMS2_k127_2987325_6 YCII-related domain K09780 - - 0.0000000000000000000000000000000000003887 143.0
CMS2_k127_2987325_7 - - - - 0.000000000000000000000000000002777 124.0
CMS2_k127_2987325_8 Oxygen-binding protein. May be involved in a storage mechanism or for delivery to oxygen-requiring enzymes. The oxygen- binding site contains two iron atoms K07216 - - 0.0000000000000000000000000005076 119.0
CMS2_k127_2987325_9 - - - - 0.0000000000000000000000005485 113.0
CMS2_k127_3031660_0 LysR substrate binding domain K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 452.0
CMS2_k127_3031660_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 398.0
CMS2_k127_3031660_2 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 312.0
CMS2_k127_3031660_3 Glutaredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000001157 196.0
CMS2_k127_3031660_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000004889 202.0
CMS2_k127_3031660_5 Copper resistance protein D - - - 0.000000000000000000000000000000000000000000000000007211 184.0
CMS2_k127_3031660_6 Protein of unknown function (DUF3530) - - - 0.0000000000000000000000002838 117.0
CMS2_k127_3031660_7 - - - - 0.0000003536 60.0
CMS2_k127_3031660_8 HAD-hyrolase-like K01091 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 0.000158 45.0
CMS2_k127_3068630_0 COG3209 Rhs family protein K11021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 347.0
CMS2_k127_3068630_1 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000002404 171.0
CMS2_k127_3068630_2 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000002378 136.0
CMS2_k127_3068630_3 Type II secretion system protein G K02456 - - 0.00000000000000000000000000003076 123.0
CMS2_k127_3068630_4 Type II secretory pathway, pseudopilin - - - 0.00000000000000000000444 98.0
CMS2_k127_3068632_0 inner membrane component K02011 - - 1.026e-231 729.0
CMS2_k127_3068632_1 Belongs to the peptidase M24B family K01262 - 3.4.11.9 6.728e-198 625.0
CMS2_k127_3068632_10 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000000000006466 228.0
CMS2_k127_3068632_11 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000000000000000000000000000000000000000000000000000001033 201.0
CMS2_k127_3068632_12 Thiol-disulfide isomerase - - - 0.000000000000000000000000000222 123.0
CMS2_k127_3068632_13 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000218 97.0
CMS2_k127_3068632_14 Belongs to the UPF0149 family K09895 - - 0.00000000000000000002085 98.0
CMS2_k127_3068632_15 TIGRFAM TIGR02449 family protein K09892 - - 0.0000002482 55.0
CMS2_k127_3068632_16 Glycine cleavage system T protein K00605 - 2.1.2.10 0.000002599 50.0
CMS2_k127_3068632_2 PFAM Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 450.0
CMS2_k127_3068632_3 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007629 449.0
CMS2_k127_3068632_4 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K03184,K03185,K18800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 449.0
CMS2_k127_3068632_5 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 357.0
CMS2_k127_3068632_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 350.0
CMS2_k127_3068632_7 chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 359.0
CMS2_k127_3068632_8 Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000369 237.0
CMS2_k127_3068632_9 chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000001063 244.0
CMS2_k127_3080421_0 Heat shock 70 kDa protein K04043 - - 1.365e-288 897.0
CMS2_k127_3080421_1 Cytochrome c-type biogenesis protein CcmF K02198 - - 6.773e-279 871.0
CMS2_k127_3080421_10 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015232,GO:0015886,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019897,GO:0019898,GO:0022857,GO:0031224,GO:0031234,GO:0032991,GO:0042623,GO:0043190,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:1901678,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000001138 232.0
CMS2_k127_3080421_11 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015886,GO:0016020,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051234,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097159,GO:0098552,GO:0098567,GO:1901363,GO:1901564,GO:1901678 - 0.00000000000000000000000000000000000000000000000000003692 190.0
CMS2_k127_3080421_12 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000001335 190.0
CMS2_k127_3080421_13 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000001167 183.0
CMS2_k127_3080421_14 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000003432 154.0
CMS2_k127_3080421_15 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000000001101 63.0
CMS2_k127_3080421_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 8.444e-250 775.0
CMS2_k127_3080421_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 427.0
CMS2_k127_3080421_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 399.0
CMS2_k127_3080421_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 299.0
CMS2_k127_3080421_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003261 268.0
CMS2_k127_3080421_7 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001494 272.0
CMS2_k127_3080421_8 TIGRFAM periplasmic protein thiol K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008662 252.0
CMS2_k127_3080421_9 Cytochrome c-type biogenesis protein K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000003201 247.0
CMS2_k127_3103743_0 nitrate nitrite transporter K02575 - - 3.202e-309 951.0
CMS2_k127_3103743_1 Major Facilitator Superfamily K02575 - - 2.597e-216 679.0
CMS2_k127_3103743_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 1.599e-211 663.0
CMS2_k127_3103743_3 Histidine kinase K07673,K07674 GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 490.0
CMS2_k127_3103743_4 Aminotransferase class I and II K00817 GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 445.0
CMS2_k127_3103743_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 287.0
CMS2_k127_3103743_6 helix_turn_helix, Lux Regulon K07684 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090352,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903314,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001344 253.0
CMS2_k127_3115081_0 DNA polymerase K02336 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 4.572e-246 778.0
CMS2_k127_3115081_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 3.457e-197 621.0
CMS2_k127_3115081_2 Bacterial regulatory proteins, crp family - - - 0.000000000000000000000000000007149 127.0
CMS2_k127_3115081_3 - - - - 0.0000000001301 61.0
CMS2_k127_3115081_4 - - - - 0.000000001806 60.0
CMS2_k127_311799_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 4.669e-199 635.0
CMS2_k127_311799_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 582.0
CMS2_k127_311799_2 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 498.0
CMS2_k127_311799_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 358.0
CMS2_k127_311799_4 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 303.0
CMS2_k127_311799_5 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001541 267.0
CMS2_k127_311799_6 Belongs to the SfsA family K06206 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044238,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004273 253.0
CMS2_k127_311799_7 protein conserved in bacteria K09928 - - 0.000000000000000000000000000000000000000000000000000000000000000002265 231.0
CMS2_k127_311799_8 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000001027 140.0
CMS2_k127_311799_9 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000006779 67.0
CMS2_k127_3129877_0 GTP-binding protein TypA K06207 - - 2.228e-294 912.0
CMS2_k127_3129877_1 Diverse 7TM receptor transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884 584.0
CMS2_k127_3129877_11 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.00000000000001811 75.0
CMS2_k127_3129877_12 Histidine Phosphotransfer domain K20976 - - 0.000000005624 61.0
CMS2_k127_3129877_2 ABC transporter K15738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 521.0
CMS2_k127_3129877_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 462.0
CMS2_k127_3129877_4 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 320.0
CMS2_k127_3129877_5 Peptidase M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 299.0
CMS2_k127_3129877_6 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002451 265.0
CMS2_k127_3129877_7 membrane K08988 - - 0.00000000000000000000000000000000000000000000000009259 190.0
CMS2_k127_3129877_8 - - - - 0.00000000000000000000000000000000000000001897 156.0
CMS2_k127_3129877_9 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000002593 145.0
CMS2_k127_3142533_0 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 1.275e-234 742.0
CMS2_k127_3142533_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 530.0
CMS2_k127_3142533_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000006951 257.0
CMS2_k127_3142533_11 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003415 258.0
CMS2_k127_3142533_12 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930,K22478 GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 0.000000000000000000000000000000000000000000000000000001539 193.0
CMS2_k127_3142533_13 Protoglobin K13590,K21019 - 2.7.7.65 0.000000000000000000000000000000000000000000000000197 190.0
CMS2_k127_3142533_14 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000003382 147.0
CMS2_k127_3142533_15 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000006833 95.0
CMS2_k127_3142533_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 484.0
CMS2_k127_3142533_3 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 382.0
CMS2_k127_3142533_4 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009073 380.0
CMS2_k127_3142533_5 Diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 371.0
CMS2_k127_3142533_6 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 351.0
CMS2_k127_3142533_7 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 343.0
CMS2_k127_3142533_8 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 340.0
CMS2_k127_3142533_9 PFAM formate nitrite transporter K06212,K21993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 324.0
CMS2_k127_315827_0 His Kinase A (phosphoacceptor) domain - - - 6.221e-194 617.0
CMS2_k127_315827_1 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 519.0
CMS2_k127_315827_2 PFAM Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 396.0
CMS2_k127_315827_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 335.0
CMS2_k127_315827_4 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001346 271.0
CMS2_k127_315827_5 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.000000000000000000000000000000000000000000000000000000000000004873 222.0
CMS2_k127_315827_6 HicB family - - - 0.00000000000000000000000000000000000000000007671 162.0
CMS2_k127_315827_7 - - - - 0.00000000000000000000000000001228 119.0
CMS2_k127_315827_8 MFS transporter - - - 0.000000259 55.0
CMS2_k127_3205154_0 PFAM FAD linked oxidase domain protein K00104 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0033554,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 1.1.3.15 6.11e-245 765.0
CMS2_k127_3205154_1 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 4.576e-239 748.0
CMS2_k127_3205154_2 FAD binding domain K11472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 419.0
CMS2_k127_3205154_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005547 273.0
CMS2_k127_3205154_4 4Fe-4S dicluster domain K11473 - - 0.00000000000000000000000000000000000000000000000000000000001193 208.0
CMS2_k127_3233148_0 Belongs to the peptidase S16 family - - - 6.05e-224 720.0
CMS2_k127_3233148_1 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 411.0
CMS2_k127_3233148_10 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000007012 169.0
CMS2_k127_3233148_11 LPP20 lipoprotein - - - 0.0000000000000000000000000000000000003657 148.0
CMS2_k127_3233148_12 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000001186 145.0
CMS2_k127_3233148_13 Methyl-accepting chemotaxis protein - - - 0.0000000000000000000009955 103.0
CMS2_k127_3233148_14 - - - - 0.000000000000002594 79.0
CMS2_k127_3233148_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 389.0
CMS2_k127_3233148_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 374.0
CMS2_k127_3233148_4 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 377.0
CMS2_k127_3233148_5 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 325.0
CMS2_k127_3233148_6 protein conserved in bacteria K09859 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 332.0
CMS2_k127_3233148_7 Peptidoglycan-synthase activator LpoB K07337 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001059 258.0
CMS2_k127_3233148_9 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000009692 168.0
CMS2_k127_3243722_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1090.0
CMS2_k127_3243722_1 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 303.0
CMS2_k127_3243722_2 Cytochrome B561 K12262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002539 266.0
CMS2_k127_3243722_3 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000009253 261.0
CMS2_k127_3243722_4 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000001069 250.0
CMS2_k127_3243722_5 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000001404 200.0
CMS2_k127_3243722_6 thiolester hydrolase activity K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000303 193.0
CMS2_k127_3243722_7 PFAM Isochorismatase - - - 0.000000000000000000000000000000000000000000000001741 179.0
CMS2_k127_3243722_8 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000001185 138.0
CMS2_k127_3243722_9 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000003777 131.0
CMS2_k127_3280090_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.191e-279 865.0
CMS2_k127_3280090_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 513.0
CMS2_k127_3280090_2 PFAM Glucose Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 385.0
CMS2_k127_3280090_3 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 369.0
CMS2_k127_3280090_4 PFAM Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002867 256.0
CMS2_k127_3280090_5 cytochrome K08738 - - 0.000000000000000000000000000000000000000000000000000000294 203.0
CMS2_k127_3280090_6 Mo-co oxidoreductase dimerisation domain K17225 - - 0.00000000000000000000000000000103 122.0
CMS2_k127_3280090_7 - - - - 0.00000000000000000000004279 103.0
CMS2_k127_3280090_8 - - - - 0.0000000000000000007244 91.0
CMS2_k127_3322910_0 Di-haem cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 376.0
CMS2_k127_3322910_1 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 366.0
CMS2_k127_3322910_2 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.000000000000000000000000000000000000000000000000000000000000000000007623 241.0
CMS2_k127_3322910_3 Bacterial protein of unknown function (DUF898) - - - 0.00000000000000000000000000000000000000000000000000000000000000002987 237.0
CMS2_k127_3322910_4 COG0501 Zn-dependent protease with chaperone function - - - 0.00000000000000000000000000000000000000000000000000001032 198.0
CMS2_k127_3322910_5 COG2199 FOG GGDEF domain K21024 - 3.1.4.52 0.0000000000000000000000002607 108.0
CMS2_k127_3322910_6 diguanylate cyclase - - - 0.0000000007026 70.0
CMS2_k127_3322910_7 Nacht domain - - - 0.000001643 60.0
CMS2_k127_3356342_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1618.0
CMS2_k127_3356342_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.721e-295 917.0
CMS2_k127_3356342_10 DsrE/DsrF-like family K07092 - - 0.0000000000000000000000000000000000000000004696 161.0
CMS2_k127_3356342_11 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.00000000000000000000000000000000000003575 151.0
CMS2_k127_3356342_12 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000007137 132.0
CMS2_k127_3356342_13 cheY-homologous receiver domain - - - 0.00000000000000000000000000005573 119.0
CMS2_k127_3356342_14 Mechanosensitive ion channel - - - 0.000000000000000000000003061 110.0
CMS2_k127_3356342_15 Protein of unknown function, DUF481 K07283 - - 0.0000000000000000002008 97.0
CMS2_k127_3356342_2 Thymidine phosphorylase K00758 - 2.4.2.4 6.3e-235 736.0
CMS2_k127_3356342_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 3.834e-194 610.0
CMS2_k127_3356342_4 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 401.0
CMS2_k127_3356342_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 377.0
CMS2_k127_3356342_6 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 320.0
CMS2_k127_3356342_7 consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000865 255.0
CMS2_k127_3356342_8 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000000000008865 235.0
CMS2_k127_3356342_9 Bacterial signalling protein N terminal repeat - - - 0.000000000000000000000000000000000000000000000000000000001603 214.0
CMS2_k127_3372078_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 582.0
CMS2_k127_3372078_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 438.0
CMS2_k127_3372078_2 Nitroreductase family K10679 - 1.5.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000791 312.0
CMS2_k127_3372078_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001267 237.0
CMS2_k127_3372078_4 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000002027 153.0
CMS2_k127_3372078_5 MAPEG family - - - 0.0000000000000000000000000000252 122.0
CMS2_k127_3372078_6 PFAM transposase IS4 family protein - - - 0.000000002213 61.0
CMS2_k127_3455623_0 COG1593 TRAP-type C4-dicarboxylate transport system large permease component K11690 GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0044425 - 4.184e-208 652.0
CMS2_k127_3455623_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 530.0
CMS2_k127_3455623_2 PFAM multicopper oxidase type K08100,K14588 - 1.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 532.0
CMS2_k127_3455623_3 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 358.0
CMS2_k127_3455623_4 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 306.0
CMS2_k127_3455623_5 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000006395 222.0
CMS2_k127_348745_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1196.0
CMS2_k127_348745_1 Belongs to the GPI family K01810 - 5.3.1.9 2.103e-218 691.0
CMS2_k127_348745_10 Belongs to the 'phage' integrase family K03111 - - 0.00001929 46.0
CMS2_k127_348745_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 4.511e-218 693.0
CMS2_k127_348745_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 2.367e-200 629.0
CMS2_k127_348745_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 495.0
CMS2_k127_348745_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000006627 206.0
CMS2_k127_348745_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000001608 175.0
CMS2_k127_348745_7 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000000000008477 128.0
CMS2_k127_348745_8 Type IX secretion system membrane protein PorP/SprF - - - 0.00000000000000000000000001721 123.0
CMS2_k127_348745_9 Type IX secretion system membrane protein PorP/SprF - - - 0.000000000000000000000005323 115.0
CMS2_k127_3572836_0 Monomeric isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1076.0
CMS2_k127_3572836_1 Glucose-regulated metallo-peptidase M90 K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001605 270.0
CMS2_k127_3572836_2 SMART ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001668 263.0
CMS2_k127_3572836_3 Tetratricopeptide repeat - - - 0.00000001619 61.0
CMS2_k127_3572836_5 Bacterial extracellular solute-binding proteins, family 3 - - - 0.0007461 50.0
CMS2_k127_3590591_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 391.0
CMS2_k127_3590591_1 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 282.0
CMS2_k127_3590591_2 1-aminocyclopropane-1-carboxylate deaminase K01505 - 3.5.99.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004885 280.0
CMS2_k127_3590591_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000524 276.0
CMS2_k127_3590591_4 Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair K03573 GO:0000018,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009036,GO:0009987,GO:0015666,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019219,GO:0019222,GO:0031323,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0043765,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001346 259.0
CMS2_k127_3590591_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000004528 237.0
CMS2_k127_3590591_6 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000168 184.0
CMS2_k127_3590591_7 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000002669 90.0
CMS2_k127_3590591_8 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000002518 84.0
CMS2_k127_359104_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 3.63e-295 921.0
CMS2_k127_359104_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 5.186e-293 904.0
CMS2_k127_359104_10 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 310.0
CMS2_k127_359104_11 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 305.0
CMS2_k127_359104_12 stress-induced protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 292.0
CMS2_k127_359104_13 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002901 279.0
CMS2_k127_359104_14 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007391 271.0
CMS2_k127_359104_15 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000008962 247.0
CMS2_k127_359104_16 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000002231 244.0
CMS2_k127_359104_17 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007982 238.0
CMS2_k127_359104_18 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000003652 235.0
CMS2_k127_359104_19 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000000000000000000002248 222.0
CMS2_k127_359104_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 4.917e-280 876.0
CMS2_k127_359104_20 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000005235 227.0
CMS2_k127_359104_21 Protein-disulfide isomerase K07396 - - 0.0000000000000000000000000000000000000000000000000000000012 208.0
CMS2_k127_359104_22 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000001743 203.0
CMS2_k127_359104_23 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000006302 200.0
CMS2_k127_359104_24 Competence protein - - - 0.0000000000000000000000000000000000000000000000000008807 192.0
CMS2_k127_359104_25 cytochrome c oxidase assembly protein K02258 - - 0.000000000000000000000000000000000000000000000000005263 188.0
CMS2_k127_359104_26 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 0.000000000000000000000000000000000000000009396 162.0
CMS2_k127_359104_27 - - - - 0.0000000000000000000000000000000000000001648 155.0
CMS2_k127_359104_28 - - - - 0.000000000000000000000000000000009574 136.0
CMS2_k127_359104_29 cheY-homologous receiver domain - - - 0.0000000000000000000000000002363 123.0
CMS2_k127_359104_3 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 8.791e-232 730.0
CMS2_k127_359104_30 Universal stress protein K06149 - - 0.000000000000000000000000006206 115.0
CMS2_k127_359104_31 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000005847 97.0
CMS2_k127_359104_32 IMP dehydrogenase activity K04767,K07182 - - 0.0000000000000000004868 95.0
CMS2_k127_359104_33 Invasion gene expression up-regulator SirB - - - 0.00000000000000001384 87.0
CMS2_k127_359104_34 Rhodanese Homology Domain - - - 0.0000000000002137 75.0
CMS2_k127_359104_35 methyltransferase activity K21310 - 2.1.1.334 0.000000000000367 78.0
CMS2_k127_359104_36 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000005976 77.0
CMS2_k127_359104_37 - - - - 0.000000000005569 68.0
CMS2_k127_359104_38 - - - - 0.000000005857 58.0
CMS2_k127_359104_39 - - - - 0.0000000151 61.0
CMS2_k127_359104_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 487.0
CMS2_k127_359104_40 Protein of unknown function (DUF504) - - - 0.00000002101 59.0
CMS2_k127_359104_41 rho-dependent transcription termination K19000 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000001694 56.0
CMS2_k127_359104_42 Protein of unknown function (DUF3392) - - - 0.0000007653 56.0
CMS2_k127_359104_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 488.0
CMS2_k127_359104_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 456.0
CMS2_k127_359104_7 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 420.0
CMS2_k127_359104_8 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 371.0
CMS2_k127_359104_9 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 370.0
CMS2_k127_3607097_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 8.538e-265 820.0
CMS2_k127_3607097_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 1.155e-241 756.0
CMS2_k127_3607097_10 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0043952,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051082,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0072321 - 0.000000000000000000000000000000000000000000000000007435 186.0
CMS2_k127_3607097_11 regulatory protein, arsR - - - 0.00000000000000000000000000000000000000000000004732 172.0
CMS2_k127_3607097_12 PFAM Rhodanese-like K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000001201 141.0
CMS2_k127_3607097_13 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000566 114.0
CMS2_k127_3607097_14 Domain of unknown function (DUF4124) - - - 0.0000000000000000000006281 102.0
CMS2_k127_3607097_2 photosynthesis K02450 - - 6.232e-225 756.0
CMS2_k127_3607097_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 6.385e-214 674.0
CMS2_k127_3607097_4 Alanine-glyoxylate amino-transferase K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 498.0
CMS2_k127_3607097_5 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 395.0
CMS2_k127_3607097_6 signal transduction histidine kinase K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007922 392.0
CMS2_k127_3607097_7 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000002484 232.0
CMS2_k127_3607097_8 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000005947 224.0
CMS2_k127_3607097_9 COG4942 Membrane-bound metallopeptidase - GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000001515 228.0
CMS2_k127_3656114_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 8.694e-208 655.0
CMS2_k127_3656114_1 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 2.545e-198 631.0
CMS2_k127_3656114_10 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 348.0
CMS2_k127_3656114_11 COG0642 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 372.0
CMS2_k127_3656114_12 KR domain K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 338.0
CMS2_k127_3656114_13 NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 327.0
CMS2_k127_3656114_14 Flagellar Assembly Protein A K09749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 308.0
CMS2_k127_3656114_15 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 321.0
CMS2_k127_3656114_16 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 293.0
CMS2_k127_3656114_17 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005833 277.0
CMS2_k127_3656114_18 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000004226 204.0
CMS2_k127_3656114_19 COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000003409 199.0
CMS2_k127_3656114_2 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 608.0
CMS2_k127_3656114_20 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503 - - 0.00000000000000000000000000000000000000000001264 164.0
CMS2_k127_3656114_21 phosphatase activity K07025,K20862 - 3.1.3.102,3.1.3.104 0.00000000000000000000000000000000000000005398 160.0
CMS2_k127_3656114_22 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.00000000000000000000000000000000000000008747 154.0
CMS2_k127_3656114_23 Belongs to the bacterial histone-like protein family - - - 0.0000000000000000000000000000000001197 136.0
CMS2_k127_3656114_24 PFAM Rieske 2Fe-2S - - - 0.0000000000000000000000000004292 118.0
CMS2_k127_3656114_25 VanZ like family - - - 0.0000000000000000000000023 106.0
CMS2_k127_3656114_26 SnoaL-like domain - - - 0.0000000000000000000003721 102.0
CMS2_k127_3656114_27 SH3 domain protein K07184 - - 0.00000001443 63.0
CMS2_k127_3656114_28 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0002418 49.0
CMS2_k127_3656114_3 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 576.0
CMS2_k127_3656114_4 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 GO:0003674,GO:0003824,GO:0004652,GO:0004810,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0070566,GO:0071704,GO:0090304,GO:1901360,GO:1990817 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 527.0
CMS2_k127_3656114_5 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 453.0
CMS2_k127_3656114_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 407.0
CMS2_k127_3656114_7 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 397.0
CMS2_k127_3656114_8 Amino Acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 382.0
CMS2_k127_3656114_9 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 354.0
CMS2_k127_3671567_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 5.928e-216 693.0
CMS2_k127_3671567_1 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 451.0
CMS2_k127_3671567_10 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000002862 141.0
CMS2_k127_3671567_11 organic phosphonate transport K02044 - - 0.000000000000000000000005012 106.0
CMS2_k127_3671567_12 Nuclease-related domain - - - 0.0000002005 59.0
CMS2_k127_3671567_2 C-terminal domain of metallo-carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 409.0
CMS2_k127_3671567_3 Xanthine and CO dehydrogenases maturation factor XdhC CoxF family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000082 262.0
CMS2_k127_3671567_4 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004551 238.0
CMS2_k127_3671567_5 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000001846 212.0
CMS2_k127_3671567_6 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000000000000000000003145 206.0
CMS2_k127_3671567_7 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000000000000000000000000000007639 162.0
CMS2_k127_3671567_8 MobA-Related Protein K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000799 163.0
CMS2_k127_3671567_9 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009274,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000005234 159.0
CMS2_k127_3700108_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 9.121e-248 771.0
CMS2_k127_3700108_1 Belongs to the GcvP family K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 597.0
CMS2_k127_3700108_2 Glycine cleavage system T protein K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 471.0
CMS2_k127_3700108_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000603 195.0
CMS2_k127_3756723_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 364.0
CMS2_k127_3756723_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 343.0
CMS2_k127_3756723_2 PFAM Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006578 267.0
CMS2_k127_3756723_3 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000002227 238.0
CMS2_k127_3756723_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000002326 226.0
CMS2_k127_3756723_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000001398 206.0
CMS2_k127_3756723_6 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000002076 201.0
CMS2_k127_3756723_7 Protein of unknown function (DUF726) - - - 0.000000000000000002321 94.0
CMS2_k127_3762775_0 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002083 284.0
CMS2_k127_3762775_1 ATP adenylyltransferase (5',5''-P-1,P-4-tetraphosphate phosphorylase II) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002356 250.0
CMS2_k127_3762775_2 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000001446 208.0
CMS2_k127_3762775_3 PFAM YCII-related K05527,K09780 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000001696 154.0
CMS2_k127_3762775_4 - - - - 0.0000000000000000004006 91.0
CMS2_k127_3762775_5 - - - - 0.000000000000000006384 89.0
CMS2_k127_3762775_6 Histidine Phosphotransfer domain - - - 0.00000000002317 69.0
CMS2_k127_3766098_0 dehydrogenases and related proteins K10219 - 1.1.1.312 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 523.0
CMS2_k127_3766098_1 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 467.0
CMS2_k127_3766098_2 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 428.0
CMS2_k127_3766098_3 Methyltransferase K02553,K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 347.0
CMS2_k127_3766098_4 Aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 324.0
CMS2_k127_3766098_5 protein conserved in bacteria K16514 GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016853,GO:0016860,GO:0016863,GO:0017144,GO:0018918,GO:0018958,GO:0019336,GO:0019396,GO:0019439,GO:0019752,GO:0032787,GO:0042537,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 5.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 320.0
CMS2_k127_3772368_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.353e-242 764.0
CMS2_k127_3772368_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 5.116e-200 632.0
CMS2_k127_3772368_10 - - - - 0.000001032 53.0
CMS2_k127_3772368_2 Belongs to the BI1 family K19416 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016021,GO:0019222,GO:0030162,GO:0031224,GO:0044425,GO:0044464,GO:0050789,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071944,GO:0080090 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001279 271.0
CMS2_k127_3772368_3 Protein of unknown function (DUF3050) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001588 248.0
CMS2_k127_3772368_4 helix_turn_helix, Lux Regulon K07689 - - 0.0000000000000000000000000000000000000000000000000000000000000000008507 235.0
CMS2_k127_3772368_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000001371 208.0
CMS2_k127_3772368_6 Peptidase S24-like - - - 0.0000000000000000000000000000000003712 139.0
CMS2_k127_3772368_8 - - - - 0.00000001807 57.0
CMS2_k127_3773933_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 344.0
CMS2_k127_3773933_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001148 272.0
CMS2_k127_3773933_2 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000002029 258.0
CMS2_k127_3773933_3 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000003603 170.0
CMS2_k127_3773933_4 PFAM Type IV pilus assembly PilZ K02676 - - 0.0000000000000000000000000000000000007308 142.0
CMS2_k127_3773933_5 COG0115 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K02619 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008696,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0019842,GO:0030170,GO:0034641,GO:0036094,GO:0042558,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 4.1.3.38 0.00000000000000000000000000002696 120.0
CMS2_k127_3788297_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 608.0
CMS2_k127_3788297_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 541.0
CMS2_k127_3788297_10 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000007553 238.0
CMS2_k127_3788297_11 Belongs to the skp family K06142 GO:0001530,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006457,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0019867,GO:0022417,GO:0022607,GO:0030288,GO:0030312,GO:0030313,GO:0031647,GO:0031975,GO:0032978,GO:0033036,GO:0034613,GO:0042597,GO:0042802,GO:0043163,GO:0043165,GO:0043170,GO:0044085,GO:0044091,GO:0044238,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0050821,GO:0051082,GO:0051179,GO:0051205,GO:0051234,GO:0051604,GO:0051641,GO:0061024,GO:0061077,GO:0065007,GO:0065008,GO:0070727,GO:0071704,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0097367,GO:1901564 - 0.00000000000000000000000001023 116.0
CMS2_k127_3788297_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 441.0
CMS2_k127_3788297_3 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 417.0
CMS2_k127_3788297_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 387.0
CMS2_k127_3788297_5 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 370.0
CMS2_k127_3788297_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 362.0
CMS2_k127_3788297_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 329.0
CMS2_k127_3788297_8 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 330.0
CMS2_k127_3788297_9 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003435 259.0
CMS2_k127_381908_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1199.0
CMS2_k127_381908_1 accessory protein K06959 - - 0.0 1047.0
CMS2_k127_381908_10 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 445.0
CMS2_k127_381908_11 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 406.0
CMS2_k127_381908_12 Protein of unknown function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 432.0
CMS2_k127_381908_13 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 378.0
CMS2_k127_381908_14 Protein of unknown function (DUF2167) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 372.0
CMS2_k127_381908_15 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 370.0
CMS2_k127_381908_16 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 364.0
CMS2_k127_381908_17 ABC transporter ATP-binding protein K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 354.0
CMS2_k127_381908_18 antiporter K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005647 352.0
CMS2_k127_381908_19 ABC transporter permease K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 334.0
CMS2_k127_381908_2 modulator of DNA gyrase K03568 - - 7.959e-225 704.0
CMS2_k127_381908_20 Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6-phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS K06958 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 333.0
CMS2_k127_381908_21 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 315.0
CMS2_k127_381908_22 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004626 283.0
CMS2_k127_381908_23 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000009331 263.0
CMS2_k127_381908_24 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000001463 247.0
CMS2_k127_381908_25 PFAM VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000004367 243.0
CMS2_k127_381908_26 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000005214 239.0
CMS2_k127_381908_27 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 0.00000000000000000000000000000000000000000000000000000000000000007231 224.0
CMS2_k127_381908_28 maF-like protein K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0047429 - 0.0000000000000000000000000000000000000000000000000000000000006325 216.0
CMS2_k127_381908_29 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000004108 192.0
CMS2_k127_381908_3 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 1.3e-214 674.0
CMS2_k127_381908_30 Zinc-ribbon containing domain - - - 0.000000000000000000000000000000000000000000005873 171.0
CMS2_k127_381908_31 PFAM toluene tolerance K07323 - - 0.000000000000000000000000000000000000000000006148 169.0
CMS2_k127_381908_32 - - - - 0.00000000000000000000000000000000000000000003756 170.0
CMS2_k127_381908_33 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000000001649 163.0
CMS2_k127_381908_34 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000206 158.0
CMS2_k127_381908_35 Methyltransferase domain - - - 0.00000000000000000000000000000000000000006259 158.0
CMS2_k127_381908_36 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.0000000000000000000000000000000000000006005 153.0
CMS2_k127_381908_37 Belongs to the UPF0307 family K09889 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000004396 145.0
CMS2_k127_381908_38 Sigma 54 modulation protein K05808 - - 0.000000000000000000000000000000000007944 138.0
CMS2_k127_381908_39 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.00000000000000000000000000000000007941 139.0
CMS2_k127_381908_4 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 3.813e-199 628.0
CMS2_k127_381908_40 - - - - 0.000000000000000000000000114 112.0
CMS2_k127_381908_41 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000000000000000000000000243 115.0
CMS2_k127_381908_42 Phosphotransferase System K11189 - - 0.0000000000000000000000003515 106.0
CMS2_k127_381908_43 MAPEG family - - - 0.00000000000000000000004279 103.0
CMS2_k127_381908_44 Protein of unknown function DUF72 - - - 0.00000000000000000000007825 106.0
CMS2_k127_381908_45 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000001488 102.0
CMS2_k127_381908_46 Belongs to the BolA IbaG family - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.000000000000000000001682 96.0
CMS2_k127_381908_47 NTP binding protein (Contains STAS domain) K07122 - - 0.000000000000002774 79.0
CMS2_k127_381908_49 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.00000000007154 69.0
CMS2_k127_381908_5 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.168e-197 623.0
CMS2_k127_381908_50 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.0000000001183 72.0
CMS2_k127_381908_51 Heavy-metal-associated domain K07213 - - 0.0000000001664 63.0
CMS2_k127_381908_52 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.0000002343 60.0
CMS2_k127_381908_6 COG1530 Ribonucleases G and E K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 1.038e-196 625.0
CMS2_k127_381908_7 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 568.0
CMS2_k127_381908_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 565.0
CMS2_k127_381908_9 Acts as a magnesium transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 494.0
CMS2_k127_3823413_0 PFAM ATP-grasp fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 569.0
CMS2_k127_3823413_1 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 477.0
CMS2_k127_3823413_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 358.0
CMS2_k127_3823413_3 PFAM Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003438 246.0
CMS2_k127_3823413_4 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000004616 155.0
CMS2_k127_3823413_5 Sulfur carrier protein which probably makes part of a sulfur-relay system K04085 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000003729 57.0
CMS2_k127_383237_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.10 7.236e-207 654.0
CMS2_k127_383237_1 Aminotransferase class I and II K02225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009521 369.0
CMS2_k127_383237_10 - - - - 0.0000000000000000000000836 104.0
CMS2_k127_383237_11 Putative motility protein - - - 0.00002726 49.0
CMS2_k127_383237_2 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 322.0
CMS2_k127_383237_3 CobD/Cbib protein K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001044 285.0
CMS2_k127_383237_4 chemotaxis K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001687 271.0
CMS2_k127_383237_5 Putative zinc- or iron-chelating domain K09160 - - 0.0000000000000000000000000000000000000000001575 165.0
CMS2_k127_383237_6 Transposase DDE domain - - - 0.000000000000000000000000000000000003709 140.0
CMS2_k127_383237_7 membrane - - - 0.000000000000000000000000000000001497 133.0
CMS2_k127_383237_8 Thioredoxin - - - 0.00000000000000000000000000000000258 131.0
CMS2_k127_383237_9 Transposase - - - 0.00000000000000000000000004793 108.0
CMS2_k127_3860736_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1458.0
CMS2_k127_3860736_1 UPF0313 protein - - - 0.0 1112.0
CMS2_k127_3860736_10 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 297.0
CMS2_k127_3860736_11 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 291.0
CMS2_k127_3860736_12 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000221 284.0
CMS2_k127_3860736_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000004863 232.0
CMS2_k127_3860736_14 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000004851 209.0
CMS2_k127_3860736_15 Thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000001598 200.0
CMS2_k127_3860736_16 AAA domain K03496 - - 0.000000000000000000000000000000000000000000000000000004735 197.0
CMS2_k127_3860736_17 response regulator receiver K03413 - - 0.000000000000000000000000000000000000000000000000000007031 191.0
CMS2_k127_3860736_18 Peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000012 198.0
CMS2_k127_3860736_19 signal peptide protein - - - 0.00000000000000000000000000000000000000000000001727 183.0
CMS2_k127_3860736_2 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 2.345e-235 749.0
CMS2_k127_3860736_20 chemotaxis signal transduction protein K03408 - - 0.0000000000000000000000000000000000000000000003376 172.0
CMS2_k127_3860736_21 - - - - 0.0000000000000000000000000000000000000000001994 160.0
CMS2_k127_3860736_22 Chemotaxis signal transduction protein K03408 - - 0.0000000000000000000000000000000000001126 148.0
CMS2_k127_3860736_23 - - - - 0.00000000000000000000000000000000005323 138.0
CMS2_k127_3860736_24 - - - - 0.00000000000000000000000000000000005987 138.0
CMS2_k127_3860736_25 Thioredoxin - - - 0.000000000000000000000000000000001371 132.0
CMS2_k127_3860736_26 Rieske-like [2Fe-2S] domain K14750 - - 0.00000000000000000000000000002262 120.0
CMS2_k127_3860736_27 - - - - 0.0000000000000000000000000007125 117.0
CMS2_k127_3860736_28 STAS domain - - - 0.00000000000000000000001998 102.0
CMS2_k127_3860736_29 - - - - 0.0000000000000000000000922 98.0
CMS2_k127_3860736_3 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 5.776e-194 611.0
CMS2_k127_3860736_30 - - - - 0.0000000000000000000005467 99.0
CMS2_k127_3860736_31 small protein containing a coiled-coil domain - - - 0.000000000000003766 78.0
CMS2_k127_3860736_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 456.0
CMS2_k127_3860736_5 chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 402.0
CMS2_k127_3860736_6 oxidoreductase FAD NAD(P)-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 362.0
CMS2_k127_3860736_7 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 357.0
CMS2_k127_3860736_8 ABC-type transport system, involved in lipoprotein release, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 356.0
CMS2_k127_3860736_9 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 319.0
CMS2_k127_3935529_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 565.0
CMS2_k127_3935529_1 peroxidase K07223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 368.0
CMS2_k127_3935529_2 EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000001303 220.0
CMS2_k127_3935529_3 Protein of unknown function (DUF3299) K09950 - - 0.000000000000000000000000000000000000000000000001827 180.0
CMS2_k127_4014576_0 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 494.0
CMS2_k127_4014576_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772,K19696 - 2.4.2.28,2.4.2.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 332.0
CMS2_k127_4014576_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 311.0
CMS2_k127_4014576_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000005555 250.0
CMS2_k127_4014576_4 phosphoribosyltransferase K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000004826 247.0
CMS2_k127_4014576_5 transmembrane transport K16052 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000003669 222.0
CMS2_k127_4014576_6 DsrE/DsrF-like family - - - 0.0000000000000000000000000000000000000000000000000000000002747 206.0
CMS2_k127_4023904_0 ggdef domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 396.0
CMS2_k127_4023904_1 Cytochrome P450 K05917 - 1.14.13.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 386.0
CMS2_k127_4023904_2 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000003095 128.0
CMS2_k127_4023904_3 Protein of unknown function (DUF3301) - - - 0.000000000000000001378 89.0
CMS2_k127_4027570_0 lysine 2,3-aminomutase - - - 6.892e-210 660.0
CMS2_k127_4027570_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 295.0
CMS2_k127_4027570_2 SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000001234 221.0
CMS2_k127_4027570_3 Caspase domain - - - 0.000000000000000000000000000000000000000000000000000000000003345 221.0
CMS2_k127_4027570_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000008364 173.0
CMS2_k127_4040673_0 Peptidase family U32 C-terminal domain K08303 - - 6.237e-205 646.0
CMS2_k127_4040673_1 COG0306 Phosphate sulphate permeases K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 3.477e-198 624.0
CMS2_k127_4040673_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 4.169e-196 620.0
CMS2_k127_4040673_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 539.0
CMS2_k127_4040673_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 333.0
CMS2_k127_4040673_5 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001738 277.0
CMS2_k127_4040673_6 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000001052 228.0
CMS2_k127_4040673_7 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000003712 55.0
CMS2_k127_4040673_8 PilZ domain - - - 0.00002366 51.0
CMS2_k127_4043868_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0 1060.0
CMS2_k127_4043868_1 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 591.0
CMS2_k127_4043868_10 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 285.0
CMS2_k127_4043868_11 Putative DNA-binding domain K09929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002412 278.0
CMS2_k127_4043868_12 Sigma factor PP2C-like phosphatases K20977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001207 282.0
CMS2_k127_4043868_13 DoxX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002229 247.0
CMS2_k127_4043868_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001286 252.0
CMS2_k127_4043868_15 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000000001714 224.0
CMS2_k127_4043868_16 Domain of unknown function (DUF1841) - - - 0.0000000000000000000000000000000000000000000004724 170.0
CMS2_k127_4043868_17 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000005895 160.0
CMS2_k127_4043868_18 DNA replication and repair protein RecF - - - 0.00000000000000000000000000000000000000001167 158.0
CMS2_k127_4043868_19 TQO small subunit DoxD K15977 - - 0.0000000000000000000000000000000000000102 151.0
CMS2_k127_4043868_2 Protein of unknown function (DUF692) K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 446.0
CMS2_k127_4043868_20 Domain of unknown function (DUF4194) - - - 0.0000000000000000000000000000000000000233 153.0
CMS2_k127_4043868_21 Anti-sigma-K factor rskA - - - 0.00000000000000000000000000000003559 135.0
CMS2_k127_4043868_22 - - - - 0.0000000006938 64.0
CMS2_k127_4043868_23 - - - - 0.0001969 49.0
CMS2_k127_4043868_3 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 405.0
CMS2_k127_4043868_4 Histidine kinase K20972 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 416.0
CMS2_k127_4043868_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 367.0
CMS2_k127_4043868_6 ATPase, AAA K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 319.0
CMS2_k127_4043868_7 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 312.0
CMS2_k127_4043868_8 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 310.0
CMS2_k127_4043868_9 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 309.0
CMS2_k127_4045785_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1148.0
CMS2_k127_4045785_1 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 2.298e-237 750.0
CMS2_k127_4045785_10 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 557.0
CMS2_k127_4045785_11 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 515.0
CMS2_k127_4045785_12 Response regulator receiver K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 500.0
CMS2_k127_4045785_13 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 484.0
CMS2_k127_4045785_14 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 447.0
CMS2_k127_4045785_15 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 427.0
CMS2_k127_4045785_16 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 409.0
CMS2_k127_4045785_17 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 403.0
CMS2_k127_4045785_18 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 395.0
CMS2_k127_4045785_19 Uncharacterised protein family (UPF0014) K02069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 345.0
CMS2_k127_4045785_2 PFAM TrkA-N domain K03499 - - 3.623e-213 670.0
CMS2_k127_4045785_20 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 348.0
CMS2_k127_4045785_21 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001142 297.0
CMS2_k127_4045785_22 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000198 280.0
CMS2_k127_4045785_23 Cation efflux family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001964 269.0
CMS2_k127_4045785_24 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000001637 248.0
CMS2_k127_4045785_25 PFAM Peptidoglycan-binding lysin domain - - - 0.000000000000000000000000000000000000000000000000000000000000007528 231.0
CMS2_k127_4045785_26 pfam abc - - - 0.0000000000000000000000000000000000000000000000000000000000001255 218.0
CMS2_k127_4045785_27 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000002258 214.0
CMS2_k127_4045785_28 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000000001937 206.0
CMS2_k127_4045785_29 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000000000000000000001508 201.0
CMS2_k127_4045785_3 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.237e-212 673.0
CMS2_k127_4045785_30 PFAM Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000001126 201.0
CMS2_k127_4045785_31 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000005859 204.0
CMS2_k127_4045785_32 NHL repeat - - - 0.000000000000000000000000000000000000000000000000001301 195.0
CMS2_k127_4045785_33 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000004166 178.0
CMS2_k127_4045785_34 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000001397 173.0
CMS2_k127_4045785_35 Sterol-binding domain protein K03690 - - 0.000000000000000000000000000000000000000000004396 172.0
CMS2_k127_4045785_36 Protein of unknown function (DUF805) - - - 0.00000000000000000000000000000000000001725 147.0
CMS2_k127_4045785_37 Ethanolamine utilisation protein EutQ K06995 - - 0.0000000000000000000000000000000000005764 140.0
CMS2_k127_4045785_38 diguanylate cyclase - - - 0.00000000000000000000000000000000001755 148.0
CMS2_k127_4045785_39 anaerobic respiration - - - 0.0000000000000000000000000000000004594 144.0
CMS2_k127_4045785_4 signal transduction histidine kinase - - - 1.391e-209 674.0
CMS2_k127_4045785_40 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.0000000000000000000000000000008115 133.0
CMS2_k127_4045785_41 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000001915 119.0
CMS2_k127_4045785_42 Prokaryotic cytochrome b561 - - - 0.00000000000000000000003376 111.0
CMS2_k127_4045785_43 PFAM Iron-binding zinc finger CDGSH type - - - 0.00000000000000000003223 91.0
CMS2_k127_4045785_44 cytochrome - - - 0.000000000000000006067 91.0
CMS2_k127_4045785_45 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000008819 89.0
CMS2_k127_4045785_46 COG2826 Transposase and inactivated derivatives, IS30 family K07482 - - 0.000000000000002472 75.0
CMS2_k127_4045785_47 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000404 85.0
CMS2_k127_4045785_48 - - - - 0.000000000173 66.0
CMS2_k127_4045785_49 Membrane fusogenic activity K09806 - - 0.000000001401 63.0
CMS2_k127_4045785_5 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 1.511e-209 661.0
CMS2_k127_4045785_51 - - - - 0.000001052 57.0
CMS2_k127_4045785_52 Belongs to the ompA family K03286 - - 0.00001881 53.0
CMS2_k127_4045785_6 Mg chelatase-related protein K07391 - - 5.001e-207 655.0
CMS2_k127_4045785_7 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 6.257e-206 651.0
CMS2_k127_4045785_8 Ammonium Transporter Family K03320 - - 1.793e-195 617.0
CMS2_k127_4045785_9 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 581.0
CMS2_k127_4088333_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.759e-256 803.0
CMS2_k127_4088333_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 517.0
CMS2_k127_4088333_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 409.0
CMS2_k127_4088333_3 - - - - 0.0000000000000000000706 96.0
CMS2_k127_4088333_4 Pentapeptide repeats (9 copies) - - - 0.000000001271 66.0
CMS2_k127_4128991_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 548.0
CMS2_k127_4128991_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 545.0
CMS2_k127_4128991_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000007961 239.0
CMS2_k127_4128991_11 Mov34 MPN PAD-1 family - - - 0.0000000000000000000000000000000000000000001592 162.0
CMS2_k127_4128991_12 - - - - 0.000000000000000000000000000000000000001964 152.0
CMS2_k127_4128991_13 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.00000000000000000000000000000000004702 141.0
CMS2_k127_4128991_14 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000004425 49.0
CMS2_k127_4128991_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 509.0
CMS2_k127_4128991_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 480.0
CMS2_k127_4128991_4 Malate quinone- oxidoreductase K00116 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.1.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 377.0
CMS2_k127_4128991_5 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 362.0
CMS2_k127_4128991_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 336.0
CMS2_k127_4128991_7 PFAM MoeZ MoeB domain K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 323.0
CMS2_k127_4128991_8 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 292.0
CMS2_k127_4128991_9 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000153 260.0
CMS2_k127_4132373_0 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 431.0
CMS2_k127_4132373_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 358.0
CMS2_k127_4132373_2 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 334.0
CMS2_k127_4132373_3 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 330.0
CMS2_k127_4132373_4 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 0.00000000000000000000000000157 112.0
CMS2_k127_4207028_0 Protein of unknown function, DUF255 K06888 - - 6.648e-236 749.0
CMS2_k127_4207028_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 502.0
CMS2_k127_4207028_10 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001611 267.0
CMS2_k127_4207028_11 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008145 248.0
CMS2_k127_4207028_12 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287,K18590 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000001027 194.0
CMS2_k127_4207028_13 protein conserved in bacteria K09912 - - 0.00000000000000000000000000000000000000000000001512 176.0
CMS2_k127_4207028_14 Cupin - - - 0.00000000000000000000000000000000000000000436 160.0
CMS2_k127_4207028_15 cellulase activity - - - 0.0000000000000000000000000000000000000001022 168.0
CMS2_k127_4207028_16 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000002364 144.0
CMS2_k127_4207028_17 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000003538 138.0
CMS2_k127_4207028_18 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000004237 140.0
CMS2_k127_4207028_19 - - - - 0.00000000000000000000000000001762 121.0
CMS2_k127_4207028_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 505.0
CMS2_k127_4207028_20 Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000001006 115.0
CMS2_k127_4207028_21 cellulase activity - - - 0.0000000000000000000000001404 121.0
CMS2_k127_4207028_22 Mu-like prophage protein Gp16 - - - 0.0000000000000000000000219 106.0
CMS2_k127_4207028_23 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000007952 100.0
CMS2_k127_4207028_24 PFAM Mor transcription activator - - - 0.000000000000000009361 87.0
CMS2_k127_4207028_25 - - - - 0.00000000000000001447 91.0
CMS2_k127_4207028_3 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 493.0
CMS2_k127_4207028_4 Methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 417.0
CMS2_k127_4207028_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 397.0
CMS2_k127_4207028_6 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 378.0
CMS2_k127_4207028_7 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 319.0
CMS2_k127_4207028_8 SMART Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001495 286.0
CMS2_k127_4207028_9 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001185 271.0
CMS2_k127_4224201_0 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 413.0
CMS2_k127_4224201_1 Putative ATP-dependant zinc protease - - - 0.00000000000000000000000005674 113.0
CMS2_k127_4224201_2 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.0000000000000001088 94.0
CMS2_k127_4277240_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase - - - 0.0 1193.0
CMS2_k127_4277240_1 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 7.108e-237 746.0
CMS2_k127_4277240_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000001593 156.0
CMS2_k127_4277240_11 Histidine kinase - - - 0.0000000000000000000000000000000007148 151.0
CMS2_k127_4277240_12 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000001668 135.0
CMS2_k127_4277240_13 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000001858 91.0
CMS2_k127_4277240_14 COG0457 FOG TPR repeat - - - 0.0000000000000000002246 101.0
CMS2_k127_4277240_15 Putative zinc-finger - - - 0.00000000000000004565 89.0
CMS2_k127_4277240_2 kinase activity - - - 5.562e-201 633.0
CMS2_k127_4277240_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 559.0
CMS2_k127_4277240_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 503.0
CMS2_k127_4277240_5 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 461.0
CMS2_k127_4277240_6 transmembrane signaling receptor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 400.0
CMS2_k127_4277240_7 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007136 281.0
CMS2_k127_4277240_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000001492 201.0
CMS2_k127_4277240_9 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000001167 185.0
CMS2_k127_4290554_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1468.0
CMS2_k127_4290554_1 E1-E2 ATPase K17686 - 3.6.3.54 1.831e-269 848.0
CMS2_k127_4290554_10 FOG PAS PAC domain K03776 - - 0.00000000000000000000000000000000000000335 150.0
CMS2_k127_4290554_11 protein conserved in bacteria - - - 0.000000000000000000000000000000000000009999 147.0
CMS2_k127_4290554_12 Sel1-like repeats. K07126 - - 0.0000000000000000000000000002496 123.0
CMS2_k127_4290554_13 Protein of unknown function (DUF2892) - - - 0.000000000000000000000000512 110.0
CMS2_k127_4290554_14 PFAM beta-lactamase domain protein - - - 0.000000000000000067 85.0
CMS2_k127_4290554_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 557.0
CMS2_k127_4290554_3 NnrS protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 300.0
CMS2_k127_4290554_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 284.0
CMS2_k127_4290554_5 Psort location OuterMembrane, score K15125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002145 258.0
CMS2_k127_4290554_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000003724 230.0
CMS2_k127_4290554_7 transcriptional regulator (AraC family) - - - 0.00000000000000000000000000000000000000000000000000000000005566 209.0
CMS2_k127_4290554_8 Peptide transporter K07326 - - 0.00000000000000000000000000000000000000000000001347 192.0
CMS2_k127_4290554_9 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0051087,GO:0071944 - 0.000000000000000000000000000000000000000002606 164.0
CMS2_k127_4422226_0 TIGRFAM cytochrome c oxidase accessory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 589.0
CMS2_k127_4422226_1 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 327.0
CMS2_k127_4422226_2 PFAM FixH - - - 0.0000000000000000000000000000000111 134.0
CMS2_k127_4422226_3 Cbb3-type cytochrome oxidase component FixQ - - - 0.0000000000000000006871 88.0
CMS2_k127_4457643_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 5.755e-275 853.0
CMS2_k127_4457643_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 398.0
CMS2_k127_4457643_2 PFAM Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 390.0
CMS2_k127_4457643_3 Protein of unknown function (DUF2797) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 374.0
CMS2_k127_4457643_4 Reduces the stability of FtsZ polymers in the presence of ATP K06916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032153,GO:0044424,GO:0044464,GO:0051301 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 333.0
CMS2_k127_4457643_5 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001443 271.0
CMS2_k127_4457643_6 Belongs to the UPF0149 family K07039 - - 0.0000000000000000000000176 108.0
CMS2_k127_4457643_7 PFAM RNP-1 like RNA-binding protein - - - 0.000000000000000001629 91.0
CMS2_k127_4457643_8 - - - - 0.0000000000000004115 85.0
CMS2_k127_4457643_9 Belongs to the SlyX family K03745 - - 0.000000000121 64.0
CMS2_k127_4493232_0 methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1695.0
CMS2_k127_4493232_1 PFAM Animal haem peroxidase K11987 - 1.14.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 481.0
CMS2_k127_4519821_0 Ferrous iron transport protein B K04759 - - 3.519e-241 764.0
CMS2_k127_4519821_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.087e-230 717.0
CMS2_k127_4519821_10 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000001244 228.0
CMS2_k127_4519821_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000001567 236.0
CMS2_k127_4519821_12 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000000000000000000007798 195.0
CMS2_k127_4519821_13 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000005139 177.0
CMS2_k127_4519821_14 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000001756 154.0
CMS2_k127_4519821_15 GGDEF domain K19707 - - 0.000000000000000000000000000000000009867 149.0
CMS2_k127_4519821_16 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins K21218 - - 0.00000000000000000000000000000000004179 145.0
CMS2_k127_4519821_17 long-chain fatty acid transport protein - - - 0.0001206 54.0
CMS2_k127_4519821_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.591e-204 645.0
CMS2_k127_4519821_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 629.0
CMS2_k127_4519821_4 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 504.0
CMS2_k127_4519821_5 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 355.0
CMS2_k127_4519821_6 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006814 284.0
CMS2_k127_4519821_7 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003006 267.0
CMS2_k127_4519821_8 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000009098 256.0
CMS2_k127_4519821_9 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000874 220.0
CMS2_k127_4553046_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 511.0
CMS2_k127_4553046_1 Belongs to the UPF0246 family K09861 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 335.0
CMS2_k127_4553046_10 - - - - 0.000000000001283 73.0
CMS2_k127_4553046_11 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000002665 68.0
CMS2_k127_4553046_12 histidine kinase A domain protein - - - 0.00000000000324 71.0
CMS2_k127_4553046_13 Transposase, IS605 OrfB family K07496 - - 0.00008226 45.0
CMS2_k127_4553046_2 Inner membrane protein PRK11099 K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000007359 258.0
CMS2_k127_4553046_3 Elongation factor P K02356 - - 0.0000000000000000000000000000000000000000000000000000000005124 207.0
CMS2_k127_4553046_4 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000000002204 209.0
CMS2_k127_4553046_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000002242 209.0
CMS2_k127_4553046_6 metal-binding protein - - - 0.0000000000000000000000000000000000000000000000000008283 186.0
CMS2_k127_4553046_7 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family - - - 0.0000000000000000000000000000000000000000001519 162.0
CMS2_k127_4553046_8 protein conserved in bacteria K09790 - - 0.00000000000000000000000000000438 123.0
CMS2_k127_4553046_9 Retron-type reverse transcriptase - - - 0.00000000000000000000006436 100.0
CMS2_k127_4607196_0 Mo-co oxidoreductase dimerisation domain K17225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 539.0
CMS2_k127_4607196_1 Belongs to the pseudouridine synthase RsuA family K06182,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 392.0
CMS2_k127_4607196_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 309.0
CMS2_k127_4607196_3 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002209 256.0
CMS2_k127_4607196_4 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.0000000000000000000000000000000000000000000000000000001844 203.0
CMS2_k127_4607196_5 - - - - 0.0000000000000000000000000000000000000000000000000001358 190.0
CMS2_k127_4607196_6 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000008135 195.0
CMS2_k127_4607196_7 - - - - 0.00000000000000000003846 96.0
CMS2_k127_4607196_8 protein conserved in bacteria K05952 - - 0.0000000000006261 70.0
CMS2_k127_462238_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 8.765e-285 885.0
CMS2_k127_462238_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 6.276e-242 754.0
CMS2_k127_462238_10 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 287.0
CMS2_k127_462238_11 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003903 281.0
CMS2_k127_462238_12 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003762 279.0
CMS2_k127_462238_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001174 283.0
CMS2_k127_462238_14 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000193 265.0
CMS2_k127_462238_15 NDK - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004749 242.0
CMS2_k127_462238_16 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000002729 233.0
CMS2_k127_462238_17 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000000003886 239.0
CMS2_k127_462238_18 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000009166 228.0
CMS2_k127_462238_19 ferredoxin, 2Fe-2S K04755 - - 0.00000000000000000000000000000000000000000000000000000000282 200.0
CMS2_k127_462238_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 1.313e-214 672.0
CMS2_k127_462238_20 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000000000000000000000936 201.0
CMS2_k127_462238_21 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K13628 - - 0.0000000000000000000000000000000000000000000000000001208 187.0
CMS2_k127_462238_22 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 0.00000000000000000000000000000000000000000004915 167.0
CMS2_k127_462238_23 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000000000000000000000000000000000000000007399 168.0
CMS2_k127_462238_24 protein conserved in bacteria - - - 0.00000000000000000000000000000000002668 142.0
CMS2_k127_462238_25 - - - - 0.000000000000000000000000000000001633 136.0
CMS2_k127_462238_26 MerR, DNA binding K08365 - - 0.000000000000000000000000000000003465 132.0
CMS2_k127_462238_27 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000005729 126.0
CMS2_k127_462238_28 MerT mercuric transport protein - - - 0.000000000000000000000000000000771 126.0
CMS2_k127_462238_29 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000611 119.0
CMS2_k127_462238_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 6.835e-207 653.0
CMS2_k127_462238_30 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.000000000000000000000000006809 110.0
CMS2_k127_462238_31 Staphylococcal nuclease homologue - - - 0.000000000000000000000000008291 110.0
CMS2_k127_462238_32 transcriptional regulator K18301 - - 0.0000000000000000000000006507 111.0
CMS2_k127_462238_33 Mercury scavenger that specifically binds to one mercury ion and which passes it to the mercuric reductase (MerA) via the MerT protein K08364 - - 0.000000000000000000007278 96.0
CMS2_k127_462238_34 Putative prokaryotic signal transducing protein - - - 0.0000000000000167 75.0
CMS2_k127_462238_35 - - - - 0.00000001376 65.0
CMS2_k127_462238_4 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 586.0
CMS2_k127_462238_5 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 565.0
CMS2_k127_462238_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 505.0
CMS2_k127_462238_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 475.0
CMS2_k127_462238_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 392.0
CMS2_k127_462238_9 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 340.0
CMS2_k127_464364_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.658e-314 972.0
CMS2_k127_464364_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 1.995e-212 668.0
CMS2_k127_464364_10 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000008244 216.0
CMS2_k127_464364_11 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000002725 192.0
CMS2_k127_464364_12 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000002421 136.0
CMS2_k127_464364_13 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000001447 132.0
CMS2_k127_464364_14 Belongs to the BolA IbaG family K05527 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0022603,GO:0022604,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000002584 128.0
CMS2_k127_464364_15 Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - 0.000000000000000000000001878 108.0
CMS2_k127_464364_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 1.643e-195 619.0
CMS2_k127_464364_3 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 474.0
CMS2_k127_464364_4 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 355.0
CMS2_k127_464364_5 PFAM Alpha beta hydrolase K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 333.0
CMS2_k127_464364_6 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 289.0
CMS2_k127_464364_8 cAMP phosphodiesterases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003837 257.0
CMS2_k127_464364_9 Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000009958 225.0
CMS2_k127_4774828_0 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 543.0
CMS2_k127_4774828_1 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 534.0
CMS2_k127_4774828_2 unusual protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 490.0
CMS2_k127_4774828_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 489.0
CMS2_k127_4774828_4 PFAM CBS domain containing protein K06189 GO:0001897,GO:0001906,GO:0001907,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009405,GO:0009987,GO:0016020,GO:0019835,GO:0019836,GO:0031640,GO:0035821,GO:0044003,GO:0044004,GO:0044179,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 332.0
CMS2_k127_4774828_5 Site-specific DNA-methyltransferase (Adenine-specific) K06223 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 326.0
CMS2_k127_4774828_6 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.00000000000000000000000000000002936 126.0
CMS2_k127_4774828_7 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000000000000504 85.0
CMS2_k127_4777529_0 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 316.0
CMS2_k127_4777529_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001361 298.0
CMS2_k127_4777529_10 Lysine methyltransferase - - - 0.0000000000000000000000001919 111.0
CMS2_k127_4777529_11 cheY-homologous receiver domain - - - 0.000000000000000000000000452 109.0
CMS2_k127_4777529_12 cheY-homologous receiver domain - - - 0.000000000000000000000000455 108.0
CMS2_k127_4777529_2 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001779 226.0
CMS2_k127_4777529_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000001548 233.0
CMS2_k127_4777529_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000001593 227.0
CMS2_k127_4777529_5 CHASE - - - 0.0000000000000000000000000000000000000000000000000000000003484 220.0
CMS2_k127_4777529_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000741 212.0
CMS2_k127_4777529_7 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000004382 184.0
CMS2_k127_4777529_8 - - - - 0.0000000000000000000000000000000003975 135.0
CMS2_k127_4777529_9 lyase activity - - - 0.000000000000000000000000000001316 132.0
CMS2_k127_4844927_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 5.013e-238 758.0
CMS2_k127_4844927_1 THUMP K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 374.0
CMS2_k127_4844927_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 338.0
CMS2_k127_4844927_3 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001772 283.0
CMS2_k127_4844927_4 inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000008061 268.0
CMS2_k127_4844927_5 PFAM Mitochondrial inner membrane translocase complex, subunit Tim44-related - - - 0.00000000000000000000000000000000000000000000000000000000000000003239 233.0
CMS2_k127_4844927_6 Uncharacterized ACR, YdiU/UPF0061 family K08997 - - 0.000000000000000007262 85.0
CMS2_k127_4844927_7 Tetratricopeptide repeat - - - 0.00000000000008247 77.0
CMS2_k127_4856741_0 alanine symporter K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 607.0
CMS2_k127_4856741_1 Peptidase family U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 484.0
CMS2_k127_4856741_10 Baseplate J-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 334.0
CMS2_k127_4856741_11 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 324.0
CMS2_k127_4856741_12 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005626 279.0
CMS2_k127_4856741_13 Tail protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002018 271.0
CMS2_k127_4856741_14 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000002499 264.0
CMS2_k127_4856741_15 DNA circularisation protein N-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000001351 244.0
CMS2_k127_4856741_16 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000001148 235.0
CMS2_k127_4856741_17 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000000000000000000008306 223.0
CMS2_k127_4856741_18 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000006844 215.0
CMS2_k127_4856741_19 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000004591 194.0
CMS2_k127_4856741_2 Radical_SAM C-terminal domain K07139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 389.0
CMS2_k127_4856741_20 CBS domain - - - 0.0000000000000000000000000000000000000000000000000006041 187.0
CMS2_k127_4856741_21 Belongs to the P(II) protein family - - - 0.000000000000000000000000000000000000000000000001373 175.0
CMS2_k127_4856741_22 aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000000004615 175.0
CMS2_k127_4856741_23 gluconokinase activity K00851 - 2.7.1.12 0.000000000000000000000000000000000000000000001968 170.0
CMS2_k127_4856741_24 Response regulator receiver - - - 0.00000000000000000000000000000000000000000006347 171.0
CMS2_k127_4856741_25 Phosphate-starvation-inducible E K13256 - - 0.0000000000000000000000000000000000000000001742 162.0
CMS2_k127_4856741_26 Paraquat-inducible protein A - - - 0.00000000000000000000000000000000000000005488 157.0
CMS2_k127_4856741_27 baseplate assembly protein V - - - 0.0000000000000000000000000000000000002097 147.0
CMS2_k127_4856741_28 Phage protein GP46 - - - 0.000000000000000000000000000000001567 134.0
CMS2_k127_4856741_29 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 6.3.1.10 0.000000000000000000000000000000002695 140.0
CMS2_k127_4856741_3 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 381.0
CMS2_k127_4856741_30 SCP-2 sterol transfer family - - - 0.00000000000000000000000000005628 122.0
CMS2_k127_4856741_31 tail collar domain protein - - - 0.00000000000000000000000000006353 128.0
CMS2_k127_4856741_32 Uncharacterised protein conserved in bacteria (DUF2313) - - - 0.000000000000000000000000003644 117.0
CMS2_k127_4856741_33 Phage tail tube protein - - - 0.000000000000000000000000004259 113.0
CMS2_k127_4856741_34 Phage tail assembly chaperone proteins, E, or 41 or 14 - - - 0.00000000000000000006552 94.0
CMS2_k127_4856741_35 aminopeptidase N K01256 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016020,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.2 0.00000000000000000163 88.0
CMS2_k127_4856741_36 - - - - 0.00000000000000009141 89.0
CMS2_k127_4856741_37 Protein of unknown function (DUF1289) - - - 0.0000000000000001835 80.0
CMS2_k127_4856741_38 Phage tail assembly chaperone protein - - - 0.0000000000003521 78.0
CMS2_k127_4856741_39 - - - - 0.000000006858 67.0
CMS2_k127_4856741_4 tail sheath - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 376.0
CMS2_k127_4856741_40 YcxB-like protein - - - 0.000607 47.0
CMS2_k127_4856741_5 Protein of unknown function (DUF1538) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 357.0
CMS2_k127_4856741_6 D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 350.0
CMS2_k127_4856741_7 Protein of unknown function (DUF1538) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 350.0
CMS2_k127_4856741_8 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 342.0
CMS2_k127_4856741_9 phage tail tape measure protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 341.0
CMS2_k127_487141_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 6.967e-299 934.0
CMS2_k127_487141_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006025 393.0
CMS2_k127_487141_2 Phosphoserine phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 302.0
CMS2_k127_487141_3 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002643 264.0
CMS2_k127_487141_4 PFAM ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000002738 235.0
CMS2_k127_487141_5 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000004389 188.0
CMS2_k127_4893039_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 395.0
CMS2_k127_4893039_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000004363 205.0
CMS2_k127_4893039_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000001427 196.0
CMS2_k127_4893039_3 - - - - 0.000000000000000000000000000000000000000000000004044 180.0
CMS2_k127_4893039_4 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000004357 187.0
CMS2_k127_4893039_5 Putative zinc ribbon domain - - - 0.00000000000000000000000008047 109.0
CMS2_k127_4896073_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0000018,GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008301,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030554,GO:0030983,GO:0031323,GO:0032136,GO:0032300,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1990391 - 6.515e-320 1000.0
CMS2_k127_4896073_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 492.0
CMS2_k127_4896073_2 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000001499 201.0
CMS2_k127_4896073_3 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000007836 184.0
CMS2_k127_4896073_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000008248 145.0
CMS2_k127_4896073_5 PFAM Thioredoxin K05838 - - 0.000000000000003141 78.0
CMS2_k127_4896073_6 PilZ domain - - - 0.000000000004557 69.0
CMS2_k127_4896073_7 COG3118 Thioredoxin domain-containing protein K03671,K05838 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0061077 - 0.00000004169 56.0
CMS2_k127_4901622_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.637e-247 770.0
CMS2_k127_4901622_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.419e-243 758.0
CMS2_k127_4901622_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000716 138.0
CMS2_k127_4901622_2 Catalyzes cross-linking of the peptidoglycan cell wall K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 1.073e-227 720.0
CMS2_k127_4901622_3 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 594.0
CMS2_k127_4901622_4 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001569 280.0
CMS2_k127_4901622_5 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003384 268.0
CMS2_k127_4901622_6 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000009282 233.0
CMS2_k127_4901622_7 PFAM FAD dependent oxidoreductase K00116 - 1.1.5.4 0.0000000000000000000000000000000000000000000000000000000000000002816 223.0
CMS2_k127_4901622_8 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.00000000000000000000000000000000000000000002534 169.0
CMS2_k127_4901622_9 Peptidoglycan polymerase that is essential for cell wall elongation K05837 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.000000000000000000000000000000000000002972 149.0
CMS2_k127_4903598_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 623.0
CMS2_k127_4903598_1 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 482.0
CMS2_k127_4903598_10 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000002942 126.0
CMS2_k127_4903598_11 Cytochrome c - - - 0.00000000000000000003104 95.0
CMS2_k127_4903598_12 transcriptional regulator K07733 - - 0.000000000000002391 78.0
CMS2_k127_4903598_15 Helix-turn-helix domain - - - 0.000000002731 64.0
CMS2_k127_4903598_2 restriction endonuclease K07448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 346.0
CMS2_k127_4903598_3 PFAM MotA TolQ ExbB proton channel K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 329.0
CMS2_k127_4903598_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022613,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0036094,GO:0042254,GO:0042274,GO:0043167,GO:0043168,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 302.0
CMS2_k127_4903598_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 282.0
CMS2_k127_4903598_6 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001272 271.0
CMS2_k127_4903598_7 Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000004167 226.0
CMS2_k127_4903598_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000002115 163.0
CMS2_k127_4903598_9 - - - - 0.0000000000000000000000000000000004388 135.0
CMS2_k127_4929561_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0 1233.0
CMS2_k127_4929561_1 LUD domain K18929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006771 571.0
CMS2_k127_4929561_2 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 314.0
CMS2_k127_4929561_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003955 247.0
CMS2_k127_4929561_4 Nucleoside 2-deoxyribosyltransferase YtoQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000004466 234.0
CMS2_k127_4929561_5 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000000000000000000000001155 201.0
CMS2_k127_4929561_6 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000005517 162.0
CMS2_k127_4929561_7 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000002692 151.0
CMS2_k127_4929561_8 LUD domain K00782 - - 0.00000000000000000000000000000442 127.0
CMS2_k127_4973181_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1029.0
CMS2_k127_4973181_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 6.332e-295 925.0
CMS2_k127_4973181_10 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000891 87.0
CMS2_k127_4973181_12 - - - - 0.00006735 46.0
CMS2_k127_4973181_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 530.0
CMS2_k127_4973181_3 G-rich domain on putative tyrosine kinase K16692 GO:0000271,GO:0003674,GO:0003824,GO:0004672,GO:0004713,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0005975,GO:0005976,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016020,GO:0016021,GO:0016051,GO:0016301,GO:0016310,GO:0016462,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018108,GO:0018193,GO:0018212,GO:0019538,GO:0031224,GO:0031226,GO:0033692,GO:0034637,GO:0034645,GO:0036211,GO:0038083,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046377,GO:0046777,GO:0071704,GO:0071944,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 342.0
CMS2_k127_4973181_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002548 244.0
CMS2_k127_4973181_5 Periplasmic protein involved in polysaccharide export K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000002932 239.0
CMS2_k127_4973181_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000424 191.0
CMS2_k127_4973181_7 Transcriptional - - - 0.0000000000000000000000000000000000000000000000000002579 186.0
CMS2_k127_4973181_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000012 160.0
CMS2_k127_4973181_9 AAA ATPase domain - - - 0.0000000000000000000000000000000002059 135.0
CMS2_k127_4978938_0 Belongs to the RimK family K05844 - - 4.286e-221 693.0
CMS2_k127_4978938_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 604.0
CMS2_k127_4978938_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000563 160.0
CMS2_k127_4978938_11 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000000008496 154.0
CMS2_k127_4978938_12 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000004313 126.0
CMS2_k127_4978938_13 Protein involved in outer membrane biogenesis K07289,K09800 - - 0.00000000000000000000000000001668 134.0
CMS2_k127_4978938_14 Thioredoxin domain - - - 0.0000000000000000000000000001493 117.0
CMS2_k127_4978938_15 helix_turn_helix, mercury resistance K19591 - - 0.000000000000000000000000001104 117.0
CMS2_k127_4978938_16 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.000000000000000000000000007291 110.0
CMS2_k127_4978938_17 Diguanylate cyclase - - - 0.0000000000000000001261 102.0
CMS2_k127_4978938_18 - - - - 0.0000001466 53.0
CMS2_k127_4978938_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 510.0
CMS2_k127_4978938_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 496.0
CMS2_k127_4978938_4 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 447.0
CMS2_k127_4978938_5 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 391.0
CMS2_k127_4978938_6 Cytochrome C biogenesis protein K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 366.0
CMS2_k127_4978938_7 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002086 276.0
CMS2_k127_4978938_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000003175 203.0
CMS2_k127_4978938_9 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.0000000000000000000000000000000000000000000000001934 189.0
CMS2_k127_4980387_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.519e-226 707.0
CMS2_k127_4980387_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 505.0
CMS2_k127_4980387_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 439.0
CMS2_k127_4980387_3 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 333.0
CMS2_k127_4980387_4 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 297.0
CMS2_k127_4980387_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000006159 231.0
CMS2_k127_4980387_6 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000002065 167.0
CMS2_k127_4980387_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000005601 160.0
CMS2_k127_5003441_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 8.949e-230 721.0
CMS2_k127_5003441_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 560.0
CMS2_k127_5003441_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 480.0
CMS2_k127_5003441_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 438.0
CMS2_k127_5003441_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 426.0
CMS2_k127_5003441_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 343.0
CMS2_k127_5003441_6 Colicin V production protein K03558 - - 0.0000000000000000000000000000000000000006445 153.0
CMS2_k127_5003441_7 Sporulation related domain K03749 - - 0.000000000000000001324 93.0
CMS2_k127_5029584_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 433.0
CMS2_k127_5029584_1 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 322.0
CMS2_k127_5029584_10 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.0000000000000000000000000002926 124.0
CMS2_k127_5029584_11 - - - - 0.0000000000000000004198 89.0
CMS2_k127_5029584_12 - - - - 0.000000000000000004077 89.0
CMS2_k127_5029584_13 decarboxylase K01617 - 4.1.1.77 0.00000000001989 73.0
CMS2_k127_5029584_2 COG1793 ATP-dependent DNA ligase K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 299.0
CMS2_k127_5029584_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 318.0
CMS2_k127_5029584_4 Protein of unknown function (DUF3581) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006483 270.0
CMS2_k127_5029584_5 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.000000000000000000000000000000000000000000000000000000000002247 215.0
CMS2_k127_5029584_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000001097 217.0
CMS2_k127_5029584_7 Pfam Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000001761 195.0
CMS2_k127_5029584_8 HNH nucleases - - - 0.0000000000000000000000000000000000000000000007408 168.0
CMS2_k127_5029584_9 Thiamine-binding protein - - - 0.00000000000000000000000000000003388 128.0
CMS2_k127_5069089_0 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 423.0
CMS2_k127_5069089_1 - - - - 0.00000000000000000000000000000000000000000000000006266 181.0
CMS2_k127_5069089_2 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000000000000000000000000002273 121.0
CMS2_k127_5070015_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 475.0
CMS2_k127_5070015_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 335.0
CMS2_k127_5070015_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 323.0
CMS2_k127_5070015_3 mercury ion transmembrane transporter activity K07213 - - 0.000000000000000000000000000000000000000006096 158.0
CMS2_k127_5070015_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000371 161.0
CMS2_k127_5070015_5 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000001724 153.0
CMS2_k127_5070015_6 Cell envelope biogenesis protein TolA K03646 - - 0.0000000000000000279 91.0
CMS2_k127_5070015_7 Sulphur transport K07112 - - 0.000001104 50.0
CMS2_k127_5137004_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 545.0
CMS2_k127_5137004_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 406.0
CMS2_k127_5137004_2 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 312.0
CMS2_k127_5137004_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 305.0
CMS2_k127_5137004_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.000000000000000000000000000000000000000000000000000000000000000001068 236.0
CMS2_k127_5137004_5 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000008432 196.0
CMS2_k127_5137004_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000002507 192.0
CMS2_k127_5137004_7 Belongs to the glutamate synthase family - - - 0.000000000000000000000000000000000000001247 149.0
CMS2_k127_5172355_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 6.022e-289 902.0
CMS2_k127_5172355_1 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 360.0
CMS2_k127_5172355_2 SRP54-type protein, GTPase domain K02404 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 353.0
CMS2_k127_5172355_3 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 316.0
CMS2_k127_5172355_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000622 252.0
CMS2_k127_5172355_5 Chemotaxis regulator that, when phosphorylated, interacts with the flagellar motor causing the flagella to spin clockwise which causes the cell to tumble K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000001587 222.0
CMS2_k127_5179180_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1079.0
CMS2_k127_5179180_1 ABC transporter K06158 - - 6.503e-228 722.0
CMS2_k127_5179180_10 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001098 265.0
CMS2_k127_5179180_11 Periplasmic 7TM domain sensor diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000005976 231.0
CMS2_k127_5179180_12 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000006718 205.0
CMS2_k127_5179180_13 PFAM SEC-C motif K09858 - - 0.0000000000000000000000000000000000000000002669 166.0
CMS2_k127_5179180_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000002002 166.0
CMS2_k127_5179180_15 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.0000000000000000000000000000000000003804 146.0
CMS2_k127_5179180_16 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.0000000000000000000000000000008392 127.0
CMS2_k127_5179180_17 Histidine Phosphotransfer domain - - - 0.00000000000000000000000000006869 127.0
CMS2_k127_5179180_18 Histidine kinase - - - 0.0000000000000000000000002672 111.0
CMS2_k127_5179180_19 - - - - 0.000000000000000000000003781 108.0
CMS2_k127_5179180_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 556.0
CMS2_k127_5179180_20 PhoQ Sensor - - - 0.00000000000000000000201 110.0
CMS2_k127_5179180_21 - - - - 0.0000000000000005106 86.0
CMS2_k127_5179180_22 - - - - 0.000000008316 59.0
CMS2_k127_5179180_3 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 440.0
CMS2_k127_5179180_4 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 426.0
CMS2_k127_5179180_5 carbohydrate transport K11688,K21395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 367.0
CMS2_k127_5179180_6 PhnA domain K06193 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 325.0
CMS2_k127_5179180_7 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 325.0
CMS2_k127_5179180_8 Protein of unknown function (DUF3549) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 293.0
CMS2_k127_5179180_9 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002035 274.0
CMS2_k127_5197015_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 595.0
CMS2_k127_5197015_1 Biological Process cation transport (GO 0006812), Molecular Function solute hydrogen antiporter activity (GO 0015299), Cellular Component integral to membrane (GO 0016021), Biological Process transmembrane transport (GO 0055085) K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 503.0
CMS2_k127_5197015_10 lactoylglutathione lyase activity K07032 - - 0.0000000000000000000000000000000000000000000000000000000000000005422 221.0
CMS2_k127_5197015_11 cheY-homologous receiver domain K20974 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000004608 232.0
CMS2_k127_5197015_12 Histidine kinase - - - 0.00000000000000000000000000000000000000000001407 176.0
CMS2_k127_5197015_13 His Kinase A (phosphoacceptor) domain - - - 0.000000000001575 81.0
CMS2_k127_5197015_14 - - - - 0.00000001252 66.0
CMS2_k127_5197015_2 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 464.0
CMS2_k127_5197015_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 422.0
CMS2_k127_5197015_4 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 411.0
CMS2_k127_5197015_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 340.0
CMS2_k127_5197015_6 Domain of unknown function (DUF4202) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 294.0
CMS2_k127_5197015_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001699 274.0
CMS2_k127_5197015_8 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000001064 252.0
CMS2_k127_5197015_9 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000001426 241.0
CMS2_k127_5217160_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 6.62e-224 704.0
CMS2_k127_5217160_1 Ammonium transporter K03320,K06580 - - 3.985e-208 651.0
CMS2_k127_5217160_2 PFAM PhoH family protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 491.0
CMS2_k127_5217160_3 Chemotaxis sensory transducer K03776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 452.0
CMS2_k127_5217160_4 MazG family K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001804 255.0
CMS2_k127_5217160_5 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000000007234 194.0
CMS2_k127_5217160_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000004498 179.0
CMS2_k127_5217160_7 Domain of unknown function (DUF4389) - - - 0.000000000000000000003708 96.0
CMS2_k127_5217160_8 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000004208 78.0
CMS2_k127_52635_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2166.0
CMS2_k127_52635_1 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 4.313e-263 838.0
CMS2_k127_52635_10 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000003529 207.0
CMS2_k127_52635_11 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000000003143 197.0
CMS2_k127_52635_12 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000171 186.0
CMS2_k127_52635_13 nuclease - - - 0.000000000000000000000000000000000000000000000001429 184.0
CMS2_k127_52635_14 - - - - 0.0000000000000000000000000000000000000000000003018 174.0
CMS2_k127_52635_15 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000001907 130.0
CMS2_k127_52635_16 Pilus assembly protein PilO K02664 - - 0.00000000000000000000000000002382 124.0
CMS2_k127_52635_17 PFAM Sporulation domain protein K03112 - - 0.0000000000000000000000002525 123.0
CMS2_k127_52635_18 50S ribosomal protein L31 K02909 - - 0.0000000000000000000000009373 104.0
CMS2_k127_52635_19 pilus assembly protein PilP K02665 - - 0.000000000000000000000008548 107.0
CMS2_k127_52635_2 Glutamate synthase K00266 GO:0003674,GO:0003824,GO:0004355,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0015930,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045181,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.13,1.4.1.14 5.885e-235 733.0
CMS2_k127_52635_20 - - - - 0.00000000000000000003317 92.0
CMS2_k127_52635_21 PFAM Fimbrial assembly K02663 - - 0.0000000000000000001618 95.0
CMS2_k127_52635_22 Protein of unknown function (DUF3135) - - - 0.00000000001227 70.0
CMS2_k127_52635_23 Cell division protein DamX K03112 GO:0003674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0030428,GO:0032153,GO:0042834,GO:0044464,GO:0097367 - 0.00000000004967 76.0
CMS2_k127_52635_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.027e-231 723.0
CMS2_k127_52635_4 type IV pilus secretin PilQ K02666 - - 2.968e-199 642.0
CMS2_k127_52635_5 PFAM malic K00029 - 1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 568.0
CMS2_k127_52635_6 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0019904,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0090304,GO:0097718,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007122 540.0
CMS2_k127_52635_7 dGTPase preferentially hydrolyzes dGTP over the other canonical NTPs K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0015949,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 517.0
CMS2_k127_52635_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 GO:0000166,GO:0003674,GO:0003824,GO:0003856,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051287,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 511.0
CMS2_k127_52635_9 COG4972 Tfp pilus assembly protein, ATPase PilM K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002698 253.0
CMS2_k127_5373072_0 PFAM von Willebrand factor type A - - - 0.0 1077.0
CMS2_k127_5373072_1 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 452.0
CMS2_k127_5373072_2 - - - - 0.0000000000000000000000000000000001428 136.0
CMS2_k127_5380277_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 3.881e-287 895.0
CMS2_k127_5380277_1 Cysteine-rich domain - - - 8.874e-236 734.0
CMS2_k127_5380277_10 - - - - 0.000000000000000000000000000000000009102 139.0
CMS2_k127_5380277_11 chemotaxis, protein - - - 0.000000000000000000000000000728 124.0
CMS2_k127_5380277_12 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000397 75.0
CMS2_k127_5380277_13 chemotaxis, protein - - - 0.0000000005494 67.0
CMS2_k127_5380277_2 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 447.0
CMS2_k127_5380277_3 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 383.0
CMS2_k127_5380277_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 314.0
CMS2_k127_5380277_5 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005901 266.0
CMS2_k127_5380277_6 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003124 257.0
CMS2_k127_5380277_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.000000000000000000000000000000000000000000000000000000005622 202.0
CMS2_k127_5380277_8 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000003612 172.0
CMS2_k127_5380277_9 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000006296 138.0
CMS2_k127_5383908_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0000287,GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006417,GO:0006418,GO:0006438,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045903,GO:0046483,GO:0046872,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0052689,GO:0060255,GO:0061475,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:2000112 6.1.1.9 0.0 1485.0
CMS2_k127_5383908_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.728e-272 843.0
CMS2_k127_5383908_10 Protein of unknown function (DUF2970) - - - 0.00001053 49.0
CMS2_k127_5383908_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.675e-264 822.0
CMS2_k127_5383908_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 604.0
CMS2_k127_5383908_4 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 431.0
CMS2_k127_5383908_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 319.0
CMS2_k127_5383908_6 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000131 224.0
CMS2_k127_5383908_7 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000002059 179.0
CMS2_k127_5383908_8 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000004461 139.0
CMS2_k127_5383908_9 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000001056 53.0
CMS2_k127_5400146_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 5.731e-208 653.0
CMS2_k127_5400146_1 Belongs to the peptidase S1C family K04691,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009897,GO:0009986,GO:0009987,GO:0010033,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031975,GO:0033554,GO:0035966,GO:0035967,GO:0042221,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051716,GO:0051788,GO:0070011,GO:0070887,GO:0071218,GO:0071310,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 390.0
CMS2_k127_5400146_2 NGG1p interacting factor 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 327.0
CMS2_k127_5400146_3 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 328.0
CMS2_k127_5400146_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002725 281.0
CMS2_k127_5400146_5 stringent starvation protein A K03599 - - 0.00000000000000000000000000001736 119.0
CMS2_k127_5424134_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 GO:0003674,GO:0003824,GO:0004474,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046912,GO:0055114,GO:0071704,GO:0072350 2.3.3.9 2.885e-312 971.0
CMS2_k127_5424134_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 2.143e-225 707.0
CMS2_k127_5424134_2 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 446.0
CMS2_k127_5424134_3 Glycolate oxidase iron-sulfur subunit K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 392.0
CMS2_k127_5424134_4 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 356.0
CMS2_k127_5424134_5 - - - - 0.000000000000000000000000000000004232 130.0
CMS2_k127_5424134_6 - - - - 0.00000000000001774 74.0
CMS2_k127_5455134_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 529.0
CMS2_k127_5455134_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 GO:0000270,GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009254,GO:0009273,GO:0009987,GO:0015929,GO:0016787,GO:0016798,GO:0030203,GO:0042546,GO:0043170,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901564 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 425.0
CMS2_k127_5455134_2 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 396.0
CMS2_k127_5455134_3 COG0668 Small-conductance mechanosensitive channel K16052 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 304.0
CMS2_k127_5455134_4 3'-5' exonuclease K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000004117 230.0
CMS2_k127_5455134_5 PFAM Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000005514 222.0
CMS2_k127_5455134_6 PFAM L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000008244 216.0
CMS2_k127_5455134_7 extracellular polysaccharide biosynthetic process K03615,K09690 - - 0.000000000001959 79.0
CMS2_k127_5459828_0 chemotaxis, protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 408.0
CMS2_k127_5459828_1 transcriptional regulator - - - 0.00000000000000000000000000000000000001199 152.0
CMS2_k127_5459828_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000001817 149.0
CMS2_k127_5459828_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000001342 128.0
CMS2_k127_5459828_4 efflux transmembrane transporter activity - - - 0.0000000000000000004289 101.0
CMS2_k127_5507371_0 His Kinase A (phosphoacceptor) domain - - - 6.203e-200 644.0
CMS2_k127_5507371_1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 561.0
CMS2_k127_5507371_10 PFAM tRNA rRNA methyltransferase (SpoU) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003851 247.0
CMS2_k127_5507371_11 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000006613 213.0
CMS2_k127_5507371_12 ABC transporter K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000004635 208.0
CMS2_k127_5507371_13 SMI1-KNR4 cell-wall - - - 0.00000000000000000000000000000000000000000000000000003658 190.0
CMS2_k127_5507371_14 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000958 154.0
CMS2_k127_5507371_16 - - - - 0.00000000000000000000000000000003223 131.0
CMS2_k127_5507371_17 Putative thioesterase (yiiD_Cterm) - - - 0.000000000000000000000000002159 116.0
CMS2_k127_5507371_18 - - - - 0.000000000000000000000000002261 117.0
CMS2_k127_5507371_19 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family - - - 0.00000000000000000000007424 100.0
CMS2_k127_5507371_2 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 505.0
CMS2_k127_5507371_20 Protein of unknown function (DUF465) - - - 0.00000000000000000118 87.0
CMS2_k127_5507371_3 Synthesizes selenophosphate from selenide and ATP K01008 GO:0000287,GO:0001887,GO:0003674,GO:0003824,GO:0004756,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009451,GO:0009987,GO:0010467,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019752,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0070329,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 490.0
CMS2_k127_5507371_4 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 462.0
CMS2_k127_5507371_5 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 415.0
CMS2_k127_5507371_6 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 326.0
CMS2_k127_5507371_7 COG1943 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 316.0
CMS2_k127_5507371_8 ABC-type tungstate transport system K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 287.0
CMS2_k127_5507371_9 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001333 261.0
CMS2_k127_5523558_0 Ammonium Transporter Family K03320 - - 1.486e-202 654.0
CMS2_k127_5523558_1 PFAM EAL domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006529 274.0
CMS2_k127_5523558_2 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.00000000000000000000000000000000000000000000000000000006401 214.0
CMS2_k127_5523558_3 Rhodanese domain protein - - - 0.000000000000000000000000000000000000000000000009144 173.0
CMS2_k127_557088_0 PFAM von Willebrand factor type A - - - 0.0 1272.0
CMS2_k127_557088_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 0.0 1217.0
CMS2_k127_557088_10 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 489.0
CMS2_k127_557088_11 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 421.0
CMS2_k127_557088_12 Transcriptional regulator K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 371.0
CMS2_k127_557088_13 Belongs to the peptidase S8 family K14645 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000003462 263.0
CMS2_k127_557088_14 Ribulose bisphosphate carboxylase, small chain - - - 0.000000000000000000000000000000000000000000000000000000000000004375 218.0
CMS2_k127_557088_15 response regulator receiver K02487,K06596 - - 0.00000000000000000000000000000000000000000000000000000000000004267 220.0
CMS2_k127_557088_16 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000007536 212.0
CMS2_k127_557088_17 Acid phosphatase homologues K12978 - - 0.00000000000000000000000000000000000000000000005829 177.0
CMS2_k127_557088_18 - - - - 0.00000000000000000000000000000000000000000000009055 170.0
CMS2_k127_557088_19 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 0.000000000000000000000000000000000008196 137.0
CMS2_k127_557088_2 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 2.549e-311 954.0
CMS2_k127_557088_20 - - - - 0.00000000000000000000000000000000001068 143.0
CMS2_k127_557088_21 CheW-like domain K06598 - - 0.000000000000000004665 89.0
CMS2_k127_557088_22 Calx-beta domain - - - 0.000000005287 71.0
CMS2_k127_557088_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.199e-252 782.0
CMS2_k127_557088_4 Belongs to the phosphoglycerate kinase family K00927 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 6.931e-226 703.0
CMS2_k127_557088_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.275e-201 633.0
CMS2_k127_557088_6 COG0191 Fructose tagatose bisphosphate aldolase K01624 - 4.1.2.13 6.271e-200 626.0
CMS2_k127_557088_7 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 1.253e-199 623.0
CMS2_k127_557088_8 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009229 577.0
CMS2_k127_557088_9 PFAM AAA domain (dynein-related subfamily) K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 505.0
CMS2_k127_5641487_0 Uncharacterized ACR, YdiU/UPF0061 family - - - 1.048e-268 836.0
CMS2_k127_5641487_1 peptidase M42 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 587.0
CMS2_k127_5641487_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001492 238.0
CMS2_k127_5641487_11 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000001422 200.0
CMS2_k127_5641487_12 - - - - 0.00000000000000000000000000000000000000000000000001734 188.0
CMS2_k127_5641487_13 response regulator containing a CheY-like receiver domain and a GGDEF domain K13069 - 2.7.7.65 0.0000000000000000000000000000000000000000000000001799 187.0
CMS2_k127_5641487_14 unsaturated fatty acid biosynthetic process K00508 GO:0001676,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016053,GO:0016213,GO:0016215,GO:0016491,GO:0016705,GO:0016717,GO:0019752,GO:0032787,GO:0042759,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0071944,GO:0072330,GO:1901576 1.14.19.3 0.000000000000000000000000000000000000000000000004956 181.0
CMS2_k127_5641487_15 diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family - - - 0.00000000000000000000000000000000000000000000106 169.0
CMS2_k127_5641487_16 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain - - - 0.0000000000000000000000000000000000000000002658 163.0
CMS2_k127_5641487_17 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000000000000000005113 154.0
CMS2_k127_5641487_18 - - - - 0.000000000000000000000000000000000004627 142.0
CMS2_k127_5641487_2 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 591.0
CMS2_k127_5641487_20 Recombination enhancement, RecA-dependent nuclease - - - 0.000000000000000000000000004355 120.0
CMS2_k127_5641487_21 Cold shock protein domain K03704 - - 0.0000000000000000000000002457 106.0
CMS2_k127_5641487_22 Putative zinc- or iron-chelating domain - - - 0.00000000000000000002849 97.0
CMS2_k127_5641487_23 COG2826 Transposase and inactivated derivatives, IS30 family K07482 - - 0.00000000000006958 71.0
CMS2_k127_5641487_24 - - - - 0.00000001296 66.0
CMS2_k127_5641487_25 - - - - 0.000172 49.0
CMS2_k127_5641487_3 7TM diverse intracellular signalling - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 498.0
CMS2_k127_5641487_4 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 422.0
CMS2_k127_5641487_5 response regulator containing a CheY-like receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 375.0
CMS2_k127_5641487_6 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008647 350.0
CMS2_k127_5641487_7 Periplasmic sensor hybrid histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 302.0
CMS2_k127_5641487_8 PFAM DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003322 273.0
CMS2_k127_5641487_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002304 228.0
CMS2_k127_5705872_0 (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 521.0
CMS2_k127_5705872_1 Protein of unknown function (DUF817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009684 395.0
CMS2_k127_5705872_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003633 279.0
CMS2_k127_5722999_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 7.971e-316 989.0
CMS2_k127_5722999_1 Thioredoxin K03671,K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 303.0
CMS2_k127_5722999_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000007269 137.0
CMS2_k127_5722999_3 Leucine carboxyl methyltransferase - - - 0.00000000000000001124 89.0
CMS2_k127_5722999_4 Psort location Cytoplasmic, score - - - 0.000000000000001815 81.0
CMS2_k127_5727285_0 COG3209 Rhs family protein K11021 - - 0.0 1253.0
CMS2_k127_5727285_1 COG1943 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 398.0
CMS2_k127_5727285_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 376.0
CMS2_k127_5790196_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K01663,K02500 GO:0000105,GO:0000107,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009382,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 418.0
CMS2_k127_5790196_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 409.0
CMS2_k127_5790196_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000009893 107.0
CMS2_k127_5790196_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000002484 78.0
CMS2_k127_5790196_2 COG0131 Imidazoleglycerol-phosphate dehydratase K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004401,GO:0004424,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042578,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 329.0
CMS2_k127_5790196_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 325.0
CMS2_k127_5790196_4 Catabolite gene activator and regulatory subunit of cAMP-dependent protein K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 320.0
CMS2_k127_5790196_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006282 271.0
CMS2_k127_5790196_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000001226 217.0
CMS2_k127_5790196_7 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000000000000000003138 211.0
CMS2_k127_5790196_8 phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.000000000000000000000000000000000000000000000004692 174.0
CMS2_k127_5790196_9 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000002754 170.0
CMS2_k127_5833223_0 COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 1.1e-205 685.0
CMS2_k127_5833223_1 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 422.0
CMS2_k127_5833223_10 TIGRFAM Pilus modification type IV, PilV K02671 - - 0.0000000000004999 78.0
CMS2_k127_5833223_2 protein conserved in bacteria K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 388.0
CMS2_k127_5833223_3 SMART Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 306.0
CMS2_k127_5833223_4 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000000007716 189.0
CMS2_k127_5833223_5 belongs to the Fur family K09826 - - 0.00000000000000000000000000000000000000000136 160.0
CMS2_k127_5833223_7 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000000000000001331 143.0
CMS2_k127_5833223_8 Putative phage abortive infection protein - - - 0.00000000000000000000005296 105.0
CMS2_k127_5833223_9 Type IV pilus assembly protein PilX C-term K02673 - - 0.000000000000002515 83.0
CMS2_k127_5858453_0 Histidine Phosphotransfer domain - - - 5.236e-240 767.0
CMS2_k127_5858453_1 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 404.0
CMS2_k127_5858453_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 306.0
CMS2_k127_5858453_3 PFAM phosphoesterase PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000003687 204.0
CMS2_k127_5858453_4 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000121 79.0
CMS2_k127_5871808_0 Exonuclease C-terminal K01141 - 3.1.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 532.0
CMS2_k127_5871808_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 526.0
CMS2_k127_5871808_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 329.0
CMS2_k127_5871808_3 PFAM methyltransferase small - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001085 269.0
CMS2_k127_5871808_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004536 251.0
CMS2_k127_5871808_5 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000002766 244.0
CMS2_k127_5871808_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000003181 217.0
CMS2_k127_5871808_7 - - - - 0.00000000000000000000000000000000000000009963 156.0
CMS2_k127_5914340_0 Citrate transporter - - - 8.432e-209 658.0
CMS2_k127_5914340_1 C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 304.0
CMS2_k127_5914340_2 Carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000002396 211.0
CMS2_k127_5914340_3 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000000003192 139.0
CMS2_k127_5914340_4 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000005092 111.0
CMS2_k127_5940898_0 Flotillin K07192 - - 1.158e-221 701.0
CMS2_k127_5940898_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 1.603e-199 630.0
CMS2_k127_5940898_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 348.0
CMS2_k127_5940898_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 308.0
CMS2_k127_5940898_12 Diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000237 281.0
CMS2_k127_5940898_13 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000241 260.0
CMS2_k127_5940898_14 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000001402 223.0
CMS2_k127_5940898_15 PFAM Cold-shock protein, DNA-binding - - - 0.0000000000000000000000000000000000000000000000000000000000001666 218.0
CMS2_k127_5940898_16 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000001832 229.0
CMS2_k127_5940898_17 Protein of unknown function (DUF1449) - - - 0.000000000000000000000000000000000000000000000000000000000002109 215.0
CMS2_k127_5940898_18 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000000007281 192.0
CMS2_k127_5940898_19 coa-binding K06929 - - 0.00000000000000000000000000000000000000000000000007187 181.0
CMS2_k127_5940898_2 response regulator receiver K10126,K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 588.0
CMS2_k127_5940898_20 Abc transporter K02012 - - 0.000000000000000000000000000000000000000000007279 176.0
CMS2_k127_5940898_21 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000001009 157.0
CMS2_k127_5940898_22 protein conserved in bacteria K09921 - - 0.000000000000000000000000000000000000001962 155.0
CMS2_k127_5940898_23 Pfam Response regulator receiver K02488 - 2.7.7.65 0.000000000000000000000000000000000747 134.0
CMS2_k127_5940898_24 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.00000000000000000000000000000002249 129.0
CMS2_k127_5940898_25 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000000000000000003923 114.0
CMS2_k127_5940898_26 - - - - 0.000000000000000000000002581 111.0
CMS2_k127_5940898_27 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000002144 95.0
CMS2_k127_5940898_28 - - - - 0.0000000003287 68.0
CMS2_k127_5940898_29 - - - - 0.00000004243 62.0
CMS2_k127_5940898_3 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 578.0
CMS2_k127_5940898_30 DnaK suppressor protein - - - 0.0000009344 54.0
CMS2_k127_5940898_31 - - - - 0.00002938 53.0
CMS2_k127_5940898_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 486.0
CMS2_k127_5940898_5 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 451.0
CMS2_k127_5940898_6 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 450.0
CMS2_k127_5940898_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 445.0
CMS2_k127_5940898_8 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 379.0
CMS2_k127_5940898_9 Belongs to the 'phage' integrase family. XerC subfamily K03733 GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 342.0
CMS2_k127_5955324_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding K01652 - 2.2.1.6 8.335e-299 923.0
CMS2_k127_5955324_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 7.725e-275 857.0
CMS2_k127_5955324_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 517.0
CMS2_k127_5955324_3 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000001132 248.0
CMS2_k127_5955324_4 PFAM macrophage migration inhibitory factor - - - 0.000000000000000000000000000008694 122.0
CMS2_k127_5955324_5 Protein of unknown function (DUF3579) - - - 0.0000000000000007999 82.0
CMS2_k127_5955324_6 Collagen triple helix repeat (20 copies) - - - 0.000000000000008989 85.0
CMS2_k127_5965283_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1049.0
CMS2_k127_5965283_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.75e-208 656.0
CMS2_k127_5965283_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008784,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0019842,GO:0030170,GO:0030203,GO:0034645,GO:0036094,GO:0036361,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0047661,GO:0048037,GO:0050662,GO:0070279,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 382.0
CMS2_k127_5965283_3 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 357.0
CMS2_k127_5965283_4 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000004192 251.0
CMS2_k127_5965283_5 Diguanylate cyclase (GGDEF domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001037 255.0
CMS2_k127_5965283_6 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000004872 209.0
CMS2_k127_5965283_7 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002553 198.0
CMS2_k127_5965283_8 membrane - - - 0.000000000000000000000000000004901 128.0
CMS2_k127_5975287_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.395e-201 634.0
CMS2_k127_5975287_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006294 386.0
CMS2_k127_5975287_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930,K22478 GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 329.0
CMS2_k127_5975287_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000001654 261.0
CMS2_k127_5975287_4 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions K05501 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000223 228.0
CMS2_k127_5975287_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000001538 187.0
CMS2_k127_5979146_0 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 370.0
CMS2_k127_5979146_1 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002488 267.0
CMS2_k127_5979146_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.0000000000000000000000000000000000000000000000000000000000000000000000003989 254.0
CMS2_k127_5979146_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000001264 209.0
CMS2_k127_5979146_4 - - - - 0.0000000000000000000000007858 108.0
CMS2_k127_5991119_0 Inorganic H+ pyrophosphatase K15987 - 3.6.1.1 1.218e-301 937.0
CMS2_k127_5991119_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.839e-257 803.0
CMS2_k127_5991119_10 - - - - 0.00000000000000000000000000000000000000000004913 164.0
CMS2_k127_5991119_11 Glutaredoxin - - - 0.00000000000000000000000000000000000000000009692 162.0
CMS2_k127_5991119_12 MOSC domain - - - 0.0000000000000000000000000000000000000013 151.0
CMS2_k127_5991119_13 - - - - 0.00000000000000000000000000005547 123.0
CMS2_k127_5991119_14 Putative quorum-sensing-regulated virulence factor K09954 - - 0.0000000000000000000000000001136 116.0
CMS2_k127_5991119_15 GIY-YIG catalytic domain K07461 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000000000004415 100.0
CMS2_k127_5991119_16 PFAM pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000004198 89.0
CMS2_k127_5991119_17 LTXXQ motif family protein - - - 0.00000000000009811 77.0
CMS2_k127_5991119_2 Na+/Pi-cotransporter K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 440.0
CMS2_k127_5991119_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 306.0
CMS2_k127_5991119_4 uracil-DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 297.0
CMS2_k127_5991119_5 Two component transcriptional regulator K11329 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007485 257.0
CMS2_k127_5991119_6 PFAM regulatory protein AsnC Lrp family K03719 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001061 247.0
CMS2_k127_5991119_7 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000038 252.0
CMS2_k127_5991119_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000003804 235.0
CMS2_k127_5991119_9 Protein of unknown function (DUF1415) - - - 0.0000000000000000000000000000000000000000000000000000000007324 207.0
CMS2_k127_6010574_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 398.0
CMS2_k127_6010574_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 355.0
CMS2_k127_6010574_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007463 279.0
CMS2_k127_6010574_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0000287,GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019899,GO:0022613,GO:0032296,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000007489 260.0
CMS2_k127_6010574_4 Involved in DNA repair and RecF pathway recombination K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 - 0.0000000000000000000000000000000000000000000000000000000000008992 218.0
CMS2_k127_6010574_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0016740,GO:0016772,GO:0016780,GO:0044238,GO:0071704,GO:1901576 2.7.8.7 0.0000000000000000000000000000009417 130.0
CMS2_k127_6010574_6 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000151 92.0
CMS2_k127_6010574_7 COG0642 Signal transduction histidine kinase K07678 GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700 2.7.13.3 0.00000000000000041 83.0
CMS2_k127_6027137_0 PFAM Type II secretion system protein E K02454 - - 3.829e-213 673.0
CMS2_k127_6027137_1 general secretion pathway protein D K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 564.0
CMS2_k127_6027137_10 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000001488 186.0
CMS2_k127_6027137_11 (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000004081 194.0
CMS2_k127_6027137_12 - - - - 0.0000000000000000000000000000000000001605 147.0
CMS2_k127_6027137_13 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000006355 147.0
CMS2_k127_6027137_14 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000001652 151.0
CMS2_k127_6027137_15 Type II secretion system protein C - - - 0.00000000000000000000000000000000092 141.0
CMS2_k127_6027137_16 Type II secretion system (T2SS), protein J K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.00000000000000000000000000000007938 132.0
CMS2_k127_6027137_17 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000000000000000002388 129.0
CMS2_k127_6027137_18 Sel1-like repeats. K07126 - - 0.000000000000000000000000000936 123.0
CMS2_k127_6027137_19 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000003389 106.0
CMS2_k127_6027137_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 439.0
CMS2_k127_6027137_20 COG2165 Type II secretory pathway, pseudopilin PulG K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000000004563 102.0
CMS2_k127_6027137_21 COG0008 Glutamyl- and glutaminyl-tRNA synthetases K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 0.0000000000000000000006636 96.0
CMS2_k127_6027137_22 general secretion pathway protein h K02457 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000000000000001787 87.0
CMS2_k127_6027137_23 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.000000000001608 74.0
CMS2_k127_6027137_24 - - - - 0.000000005918 61.0
CMS2_k127_6027137_25 Type II secretion system (T2SS), protein N K02463 - - 0.000000209 61.0
CMS2_k127_6027137_26 energy transducer activity K03832 - - 0.00000322 57.0
CMS2_k127_6027137_27 - - - - 0.000004207 49.0
CMS2_k127_6027137_3 General secretion pathway protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006504 385.0
CMS2_k127_6027137_4 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 375.0
CMS2_k127_6027137_5 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 351.0
CMS2_k127_6027137_6 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 337.0
CMS2_k127_6027137_7 short-chain dehydrogenase reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 326.0
CMS2_k127_6027137_8 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000000000000000003769 235.0
CMS2_k127_6027137_9 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000002027 205.0
CMS2_k127_6049456_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1259.0
CMS2_k127_6049456_1 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 1.551e-215 683.0
CMS2_k127_6049456_10 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000002156 188.0
CMS2_k127_6049456_11 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.0000000000000000001014 89.0
CMS2_k127_6049456_12 - - - - 0.000000001271 66.0
CMS2_k127_6049456_13 - K06950 - - 0.00000000188 63.0
CMS2_k127_6049456_14 pilus assembly protein PilE K02655 - - 0.000122 50.0
CMS2_k127_6049456_15 Belongs to the N-Me-Phe pilin family K02650 - - 0.0002651 49.0
CMS2_k127_6049456_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 512.0
CMS2_k127_6049456_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009361,GO:0009987,GO:0016310,GO:0019538,GO:0032991,GO:0036211,GO:0042709,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0046777,GO:0071704,GO:1901564,GO:1902494 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 485.0
CMS2_k127_6049456_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 488.0
CMS2_k127_6049456_5 PFAM Type II secretion system F domain K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 403.0
CMS2_k127_6049456_6 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 326.0
CMS2_k127_6049456_7 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 318.0
CMS2_k127_6049456_8 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 319.0
CMS2_k127_6049456_9 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000001759 224.0
CMS2_k127_6096105_0 SMART Elongator protein 3 MiaB NifB K09711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 406.0
CMS2_k127_6096105_1 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006122 255.0
CMS2_k127_6096105_2 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes K03800 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000046 249.0
CMS2_k127_6096105_3 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.00000000000000000000000000000000000000000000000000000000000000000001062 252.0
CMS2_k127_6096105_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000002209 213.0
CMS2_k127_6096105_5 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000000002772 139.0
CMS2_k127_6096105_6 PFAM Rhodanese-like - - - 0.00000000000000000000000126 106.0
CMS2_k127_6096105_7 Sulfur oxidation K17223 - - 0.00000000000000000000008515 98.0
CMS2_k127_6096105_8 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000003853 94.0
CMS2_k127_6096105_9 Sulfur oxidation K17223 - - 0.00000113 52.0
CMS2_k127_6113208_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1395.0
CMS2_k127_6113208_1 Conserved region in glutamate synthase K22083 - 2.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 497.0
CMS2_k127_6113208_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 469.0
CMS2_k127_6113208_3 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000001212 179.0
CMS2_k127_612270_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1116.0
CMS2_k127_612270_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 5.87e-206 645.0
CMS2_k127_612270_2 Alternative locus ID K01835 - 5.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 366.0
CMS2_k127_612270_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004653 285.0
CMS2_k127_612270_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000003374 93.0
CMS2_k127_612270_5 protein phosphatase regulator activity K11584 - - 0.000009517 57.0
CMS2_k127_6200151_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 1.899e-212 668.0
CMS2_k127_6200151_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 1.745e-197 619.0
CMS2_k127_6200151_10 PFAM lipopolysaccharide biosynthesis protein - - - 0.0004512 44.0
CMS2_k127_6200151_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 599.0
CMS2_k127_6200151_3 major facilitator superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 450.0
CMS2_k127_6200151_4 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 406.0
CMS2_k127_6200151_5 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 378.0
CMS2_k127_6200151_6 TIGRFAM 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 294.0
CMS2_k127_6200151_7 May be involved in the biosynthesis of molybdopterin K03638,K03831 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0032324,GO:0034641,GO:0042278,GO:0042802,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000003876 248.0
CMS2_k127_6200151_8 PFAM S23 ribosomal protein - - - 0.000000000000000000000000000000000000000004905 157.0
CMS2_k127_6200151_9 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 0.00000000007374 64.0
CMS2_k127_6299980_0 Chemotaxis protein histidine kinase and related K03407 - 2.7.13.3 5.666e-252 797.0
CMS2_k127_6299980_1 PFAM Radical SAM K04069 - 1.97.1.4 2.941e-194 611.0
CMS2_k127_6299980_10 Pentapeptide repeats (8 copies) - - - 0.000000000000000000000000000000000000000000000000000215 196.0
CMS2_k127_6299980_11 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000004033 179.0
CMS2_k127_6299980_12 TIGRFAM molybdenum cofactor synthesis K03831 - 2.7.7.75 0.00000000000000000000000000002692 121.0
CMS2_k127_6299980_13 FlhB HrpN YscU SpaS Family K04061 - - 0.00000000000000000000001665 102.0
CMS2_k127_6299980_14 - - - - 0.000000000000000000000375 105.0
CMS2_k127_6299980_15 Flagellar hook-length control protein FliK - - - 0.000000000000000000002034 108.0
CMS2_k127_6299980_16 Protein of unknown function (DUF2802) - - - 0.0000000000008182 74.0
CMS2_k127_6299980_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 411.0
CMS2_k127_6299980_3 this protein with a related protein (a MotB homolog) forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 323.0
CMS2_k127_6299980_4 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 319.0
CMS2_k127_6299980_5 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 313.0
CMS2_k127_6299980_6 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.000000000000000000000000000000000000000000000000000000000000000000001397 243.0
CMS2_k127_6299980_7 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000003552 239.0
CMS2_k127_6299980_8 COG0835 Chemotaxis signal transduction protein K03408 - - 0.000000000000000000000000000000000000000000000000000000000000006029 219.0
CMS2_k127_6299980_9 pfam ammecr1 K09141 - - 0.00000000000000000000000000000000000000000000000000000000002573 211.0
CMS2_k127_6311279_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1034.0
CMS2_k127_6311279_1 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001929 243.0
CMS2_k127_6311279_2 Part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000001507 144.0
CMS2_k127_6311279_3 cheY-homologous receiver domain K03413 - - 0.0003462 48.0
CMS2_k127_635558_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1160.0
CMS2_k127_635558_1 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 522.0
CMS2_k127_635558_2 COG0209 Ribonucleotide reductase, alpha subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 344.0
CMS2_k127_635558_3 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 304.0
CMS2_k127_635558_4 Membrane-associated sensor domain - - - 0.00000002064 58.0
CMS2_k127_635558_5 Histidine kinase K02660,K11525 - - 0.0008684 44.0
CMS2_k127_6411504_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 339.0
CMS2_k127_6411504_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004382 270.0
CMS2_k127_6411504_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004845 285.0
CMS2_k127_6411504_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 258.0
CMS2_k127_6411504_4 Protein of unknown function (DUF489) K07153 - - 0.0000000000000000000000000000000000000000000000000000000001287 210.0
CMS2_k127_6411504_5 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000001821 204.0
CMS2_k127_6496344_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1465.0
CMS2_k127_6496344_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 574.0
CMS2_k127_6496344_2 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008902 421.0
CMS2_k127_6593212_0 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 3.776e-195 621.0
CMS2_k127_6593212_1 TIGRFAM dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 526.0
CMS2_k127_6593212_10 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 285.0
CMS2_k127_6593212_11 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004171 253.0
CMS2_k127_6593212_12 phosphoribosyltransferase K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000004678 229.0
CMS2_k127_6593212_13 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000001237 218.0
CMS2_k127_6593212_14 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000009886 226.0
CMS2_k127_6593212_15 TIGRFAM TonB K03832 - - 0.00000000000000000000000000000000000000000000000000000009048 205.0
CMS2_k127_6593212_16 Response regulator receiver domain K02657,K03413 - - 0.00000000000000000000000000000000000000000000000000001428 191.0
CMS2_k127_6593212_17 HPP family K07168 - - 0.0000000000000000000000000000000000000000000000003516 181.0
CMS2_k127_6593212_18 PFAM Response regulator receiver domain K02658 - - 0.000000000000000000000000000000000000000000000003584 175.0
CMS2_k127_6593212_19 integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000000005791 176.0
CMS2_k127_6593212_2 PFAM Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 512.0
CMS2_k127_6593212_20 chemotaxis K02660 - - 0.000000000000000000000000000000000000000000001004 179.0
CMS2_k127_6593212_21 COG1943 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000001088 147.0
CMS2_k127_6593212_22 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000000000000000000008204 141.0
CMS2_k127_6593212_23 Response regulator receiver domain K03413 GO:0000287,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006468,GO:0006473,GO:0006475,GO:0006793,GO:0006796,GO:0006807,GO:0006928,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0016310,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0023014,GO:0023052,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0048870,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0065007,GO:0071704,GO:0071973,GO:0097588,GO:1901564 - 0.0000000000000000000000000000004811 127.0
CMS2_k127_6593212_24 DUF167 K09131 - - 0.00000000000000000000000001256 111.0
CMS2_k127_6593212_25 chemotaxis signal transduction protein K02659 - - 0.000000000000000000176 95.0
CMS2_k127_6593212_26 diguanylate cyclase - - - 0.0000000000052 77.0
CMS2_k127_6593212_27 Belongs to the 'phage' integrase family - - - 0.000000009261 61.0
CMS2_k127_6593212_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 481.0
CMS2_k127_6593212_4 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 430.0
CMS2_k127_6593212_5 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 417.0
CMS2_k127_6593212_6 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 386.0
CMS2_k127_6593212_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 351.0
CMS2_k127_6593212_8 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 313.0
CMS2_k127_6593212_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 310.0
CMS2_k127_6614136_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009330,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0032991,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0097659,GO:0140097,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.0 1169.0
CMS2_k127_6614136_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 602.0
CMS2_k127_6614136_10 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000001038 108.0
CMS2_k127_6614136_11 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000003992 76.0
CMS2_k127_6614136_12 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000008271 77.0
CMS2_k127_6614136_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 568.0
CMS2_k127_6614136_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 507.0
CMS2_k127_6614136_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 445.0
CMS2_k127_6614136_5 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 435.0
CMS2_k127_6614136_6 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 301.0
CMS2_k127_6614136_7 zinc protease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002282 263.0
CMS2_k127_6614136_8 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000003328 167.0
CMS2_k127_6614136_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000000000005728 121.0
CMS2_k127_6630236_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 7.198e-304 941.0
CMS2_k127_6630236_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.139e-275 853.0
CMS2_k127_6630236_10 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000001281 213.0
CMS2_k127_6630236_11 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000007311 196.0
CMS2_k127_6630236_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000002219 179.0
CMS2_k127_6630236_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000001256 164.0
CMS2_k127_6630236_14 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000007324 134.0
CMS2_k127_6630236_15 ATP synthase I chain K02116 - - 0.0000008881 55.0
CMS2_k127_6630236_16 diguanylate cyclase - - - 0.0006157 48.0
CMS2_k127_6630236_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.139e-267 835.0
CMS2_k127_6630236_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 5.311e-253 785.0
CMS2_k127_6630236_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006629,GO:0006725,GO:0006793,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009225,GO:0009226,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0018130,GO:0019134,GO:0019438,GO:0030203,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0042546,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046872,GO:0055086,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 543.0
CMS2_k127_6630236_5 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 413.0
CMS2_k127_6630236_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 405.0
CMS2_k127_6630236_7 ATPases involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 374.0
CMS2_k127_6630236_8 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 357.0
CMS2_k127_6630236_9 Metal dependent phosphohydrolases with conserved 'HD' motif. K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001711 273.0
CMS2_k127_6666244_0 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 1.087e-280 883.0
CMS2_k127_6666244_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.3e-239 744.0
CMS2_k127_6666244_10 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000008565 241.0
CMS2_k127_6666244_11 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000000000000000009366 96.0
CMS2_k127_6666244_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.434e-229 715.0
CMS2_k127_6666244_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 572.0
CMS2_k127_6666244_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 338.0
CMS2_k127_6666244_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 334.0
CMS2_k127_6666244_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 310.0
CMS2_k127_6666244_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 297.0
CMS2_k127_6666244_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001209 279.0
CMS2_k127_6666244_9 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001424 248.0
CMS2_k127_6673121_0 TIGRFAM Phage - - - 1.387e-262 819.0
CMS2_k127_6673121_1 Protein of unknown function (DUF935) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 615.0
CMS2_k127_6673121_2 PFAM Phage Mu protein F like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 384.0
CMS2_k127_6673121_3 Protein of unknown function (DUF1804) - - - 0.0000000000000000000000000000000000000000000000000000000000003045 214.0
CMS2_k127_6673121_4 - - - - 0.0000000000000000000000000000000002573 136.0
CMS2_k127_6673121_5 - - - - 0.000000000000000000000000001017 113.0
CMS2_k127_6673121_6 - - - - 0.00000000000004554 78.0
CMS2_k127_6673121_8 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000001933 52.0
CMS2_k127_6757942_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 5.196e-205 646.0
CMS2_k127_6757942_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 420.0
CMS2_k127_6757942_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000001505 150.0
CMS2_k127_6757942_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000151 82.0
CMS2_k127_6768711_0 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0 1714.0
CMS2_k127_6768711_1 Belongs to the CarA family K01956 GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 4.105e-201 631.0
CMS2_k127_6768711_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 552.0
CMS2_k127_6768711_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 449.0
CMS2_k127_6768711_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 398.0
CMS2_k127_6768711_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 296.0
CMS2_k127_6768711_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003491 252.0
CMS2_k127_6768711_7 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000004965 238.0
CMS2_k127_6768711_8 CRS1_YhbY K07574 - - 0.0000000000000000000000001572 109.0
CMS2_k127_6793005_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1105.0
CMS2_k127_6793005_1 DNA segregation ATPase FtsK SpoIIIE K03466 - - 1.742e-281 884.0
CMS2_k127_6793005_10 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 440.0
CMS2_k127_6793005_11 alanine dehydrogenase K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 422.0
CMS2_k127_6793005_12 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 421.0
CMS2_k127_6793005_13 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 323.0
CMS2_k127_6793005_14 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 299.0
CMS2_k127_6793005_15 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 297.0
CMS2_k127_6793005_16 Two component signalling adaptor domain K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006326 271.0
CMS2_k127_6793005_17 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000003938 258.0
CMS2_k127_6793005_18 TIGRFAM channel protein, hemolysin III family K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000003334 241.0
CMS2_k127_6793005_19 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000001465 237.0
CMS2_k127_6793005_2 Diguanylate cyclase - - - 7.778e-210 667.0
CMS2_k127_6793005_20 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000004838 203.0
CMS2_k127_6793005_21 PFAM methyltransferase - - - 0.00000000000000000000000000000000000000000000000001267 188.0
CMS2_k127_6793005_22 - - - - 0.000000000000000000000000000000000000000000005669 169.0
CMS2_k127_6793005_23 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.0000000000000000000000000000000000000000001823 162.0
CMS2_k127_6793005_24 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000223 151.0
CMS2_k127_6793005_25 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000006109 153.0
CMS2_k127_6793005_26 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.00000000000000000000000000000000000001146 149.0
CMS2_k127_6793005_27 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000001484 138.0
CMS2_k127_6793005_28 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000000000007962 122.0
CMS2_k127_6793005_29 Virulence factor BrkB - - - 0.0000000000000000000000000000154 129.0
CMS2_k127_6793005_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 8.569e-203 638.0
CMS2_k127_6793005_30 TIGRFAM cold shock domain protein CspD K03704 - - 0.0000000000000000000000000756 108.0
CMS2_k127_6793005_4 ATPase (AAA K07478 - - 8.7e-201 633.0
CMS2_k127_6793005_5 HELICc2 K03722 GO:0003674,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:1901360 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 597.0
CMS2_k127_6793005_6 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 512.0
CMS2_k127_6793005_7 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 481.0
CMS2_k127_6793005_8 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 466.0
CMS2_k127_6793005_9 PFAM Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 451.0
CMS2_k127_6796899_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00651 - 2.3.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 471.0
CMS2_k127_6796899_1 (ABC) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 432.0
CMS2_k127_6796899_2 ion transport protein K08714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 354.0
CMS2_k127_6796899_3 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 321.0
CMS2_k127_6796899_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 287.0
CMS2_k127_6796899_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001288 243.0
CMS2_k127_6796899_6 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000004881 222.0
CMS2_k127_6796899_7 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000009946 212.0
CMS2_k127_6796899_8 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K20978 - - 0.0000000000000000000002625 99.0
CMS2_k127_6796899_9 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.000000001693 66.0
CMS2_k127_6815167_0 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 5.37e-211 660.0
CMS2_k127_6815167_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 605.0
CMS2_k127_6815167_10 TIGRFAM squalene synthase HpnC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 308.0
CMS2_k127_6815167_11 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001353 273.0
CMS2_k127_6815167_12 PFAM HhH-GPD K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002873 249.0
CMS2_k127_6815167_13 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000038 252.0
CMS2_k127_6815167_14 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001413 242.0
CMS2_k127_6815167_15 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.00000000000000000000007796 98.0
CMS2_k127_6815167_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 436.0
CMS2_k127_6815167_3 DNA recombination protein RmuC K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 428.0
CMS2_k127_6815167_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 368.0
CMS2_k127_6815167_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 347.0
CMS2_k127_6815167_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 365.0
CMS2_k127_6815167_7 metal-dependent phosphoesterases (PHP family) K07053 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004534,GO:0004536,GO:0004540,GO:0005488,GO:0006139,GO:0006259,GO:0006521,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008409,GO:0009987,GO:0010565,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016796,GO:0016895,GO:0016896,GO:0019222,GO:0030145,GO:0031323,GO:0033238,GO:0034641,GO:0035312,GO:0042578,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0062012,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0090357,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 332.0
CMS2_k127_6815167_8 Belongs to the SUA5 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 322.0
CMS2_k127_6815167_9 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 321.0
CMS2_k127_6877469_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1341.0
CMS2_k127_6877469_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 8.888e-231 721.0
CMS2_k127_6877469_10 FAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 303.0
CMS2_k127_6877469_11 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002954 286.0
CMS2_k127_6877469_12 PFAM ABC transporter substrate binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005124 253.0
CMS2_k127_6877469_13 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005874 242.0
CMS2_k127_6877469_14 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001124 242.0
CMS2_k127_6877469_15 subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000001961 241.0
CMS2_k127_6877469_16 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000001876 197.0
CMS2_k127_6877469_17 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000002999 178.0
CMS2_k127_6877469_18 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000003972 182.0
CMS2_k127_6877469_19 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000003432 153.0
CMS2_k127_6877469_2 Major Facilitator - - - 1.167e-211 664.0
CMS2_k127_6877469_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000002834 139.0
CMS2_k127_6877469_22 CDP-archaeol synthase K19664 - 2.7.7.67 0.000000000000000000000000000001198 127.0
CMS2_k127_6877469_23 - - - - 0.0000000000000000000002169 110.0
CMS2_k127_6877469_24 Transfers a succinyl group from succinyl-CoA to L- serine, forming succinyl-L-serine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.00000000000000001974 86.0
CMS2_k127_6877469_26 alpha/beta hydrolase fold - - - 0.0000000002397 63.0
CMS2_k127_6877469_3 Histidine kinase K05962 - 2.7.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 470.0
CMS2_k127_6877469_4 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 451.0
CMS2_k127_6877469_5 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 375.0
CMS2_k127_6877469_6 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 355.0
CMS2_k127_6877469_7 Thioredoxin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 344.0
CMS2_k127_6877469_8 COG0616 Periplasmic serine proteases (ClpP class) K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 328.0
CMS2_k127_6877469_9 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 GO:0000287,GO:0000966,GO:0000967,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008312,GO:0008995,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016787,GO:0016788,GO:0017151,GO:0019222,GO:0019439,GO:0019899,GO:0022607,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034655,GO:0034660,GO:0042254,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043462,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0046872,GO:0048519,GO:0050789,GO:0050790,GO:0051095,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051336,GO:0060255,GO:0065003,GO:0065007,GO:0065009,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902280 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 303.0
CMS2_k127_6879501_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113,GO:2000765,GO:2000766 - 2.544e-277 863.0
CMS2_k127_6879501_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 3.082e-206 649.0
CMS2_k127_6879501_10 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000001885 164.0
CMS2_k127_6879501_11 Pfam:DUF1049 K08992 - - 0.00000000000001109 77.0
CMS2_k127_6879501_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 603.0
CMS2_k127_6879501_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 579.0
CMS2_k127_6879501_4 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 490.0
CMS2_k127_6879501_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 479.0
CMS2_k127_6879501_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 457.0
CMS2_k127_6879501_7 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 335.0
CMS2_k127_6879501_8 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015939,GO:0015940,GO:0015949,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001549 281.0
CMS2_k127_6879501_9 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000007768 169.0
CMS2_k127_6892378_0 Transposase K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 430.0
CMS2_k127_6892378_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 407.0
CMS2_k127_6892378_10 - - - - 0.0000000000000000000000009105 116.0
CMS2_k127_6892378_11 Protein of unknown function (DUF1320) - - - 0.0000000000000000002524 93.0
CMS2_k127_6892378_12 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000002409 86.0
CMS2_k127_6892378_13 TIGRFAM phage virion morphogenesis - - - 0.000000000000003996 81.0
CMS2_k127_6892378_16 Protein of unknown function (DUF2635) - - - 0.00001196 50.0
CMS2_k127_6892378_2 AAA domain K07132 - 3.6.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 343.0
CMS2_k127_6892378_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 323.0
CMS2_k127_6892378_4 Serine dehydrogenase proteinase - - - 0.000000000000000000000000000000000000000000000000000000000000000005234 238.0
CMS2_k127_6892378_5 Tail sheath - - - 0.0000000000000000000000000000000000000000000000000001497 191.0
CMS2_k127_6892378_6 protein B3ORF37 Bacteriophage B3 gi 33338631 gb AAQ13955.1 - - - 0.000000000000000000000000000001341 126.0
CMS2_k127_6892378_7 - - - - 0.000000000000000000000000000002516 125.0
CMS2_k127_6892378_8 - - - - 0.00000000000000000000000000008032 120.0
CMS2_k127_6892378_9 mu-like prophage - - - 0.0000000000000000000000001932 113.0
CMS2_k127_6955179_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 5.212e-209 653.0
CMS2_k127_6955179_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 408.0
CMS2_k127_6955179_2 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 354.0
CMS2_k127_6955179_3 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000008972 157.0
CMS2_k127_6955179_4 signal sequence binding - - - 0.00000000000000000000000001161 117.0
CMS2_k127_6955179_5 Protein of unknown function (DUF2909) - - - 0.000000001218 61.0
CMS2_k127_696759_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 1.759e-202 635.0
CMS2_k127_696759_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 567.0
CMS2_k127_696759_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 363.0
CMS2_k127_696759_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 346.0
CMS2_k127_696759_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000424 249.0
CMS2_k127_696759_5 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000001992 257.0
CMS2_k127_696759_6 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000001329 239.0
CMS2_k127_696759_7 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000002556 204.0
CMS2_k127_696759_8 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000006059 202.0
CMS2_k127_6969060_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 1.04e-299 942.0
CMS2_k127_6969060_1 Succinyldiaminopimelate K14261,K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005141 576.0
CMS2_k127_6969060_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 467.0
CMS2_k127_6969060_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000003337 233.0
CMS2_k127_6969060_4 ArsC family K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.000000000000000000000000000000000000000000000006149 176.0
CMS2_k127_6969060_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000001149 148.0
CMS2_k127_6969060_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000006716 102.0
CMS2_k127_6969060_7 HDOD domain - - - 0.00000000000004081 82.0
CMS2_k127_6969060_8 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.00000008929 53.0
CMS2_k127_6984982_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 9.217e-266 821.0
CMS2_k127_6984982_1 TIGRFAM cytochrome c oxidase accessory protein - - - 8.966e-197 622.0
CMS2_k127_6984982_2 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 391.0
CMS2_k127_6984982_3 TIGRFAM cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 347.0
CMS2_k127_6984982_4 Inositol monophosphatase family K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 286.0
CMS2_k127_6984982_5 FixH family K09926 - - 0.0000000000000000000000000000000003263 138.0
CMS2_k127_6984982_6 - - - - 0.00000000000000000004171 93.0
CMS2_k127_6984982_7 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.000000000003539 69.0
CMS2_k127_6984982_8 - - - - 0.00000000002853 66.0
CMS2_k127_7006559_0 Domain of unknown function (DUF1974) K06445 - - 9.708e-303 947.0
CMS2_k127_7006559_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.267e-280 887.0
CMS2_k127_7006559_10 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 452.0
CMS2_k127_7006559_11 COG1718 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 439.0
CMS2_k127_7006559_12 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 437.0
CMS2_k127_7006559_13 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 409.0
CMS2_k127_7006559_14 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 405.0
CMS2_k127_7006559_15 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 393.0
CMS2_k127_7006559_16 pfam mofrl K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 341.0
CMS2_k127_7006559_17 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 331.0
CMS2_k127_7006559_18 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008832 322.0
CMS2_k127_7006559_19 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 300.0
CMS2_k127_7006559_2 PFAM binding-protein-dependent transport systems inner membrane component K02037 - - 8.743e-268 844.0
CMS2_k127_7006559_20 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 312.0
CMS2_k127_7006559_21 Pyrimidine dimer DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000263 274.0
CMS2_k127_7006559_22 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001145 275.0
CMS2_k127_7006559_23 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004683 273.0
CMS2_k127_7006559_24 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000172 251.0
CMS2_k127_7006559_25 Phosphonate ABC transporter, periplasmic K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003853 254.0
CMS2_k127_7006559_26 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000179 248.0
CMS2_k127_7006559_27 TIGRFAM phosphate phosphite phosphonate ABC transporters, periplasmic binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005311 248.0
CMS2_k127_7006559_28 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006909 245.0
CMS2_k127_7006559_29 Pentapeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000004013 240.0
CMS2_k127_7006559_3 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 2.477e-254 802.0
CMS2_k127_7006559_30 lipoprotein Blc K03098 - - 0.00000000000000000000000000000000000000000000000000000000000000001507 228.0
CMS2_k127_7006559_31 PFAM histidine kinase, HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000002177 235.0
CMS2_k127_7006559_32 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000001238 183.0
CMS2_k127_7006559_33 Acyl-CoA hydrolase K10806 - - 0.000000000000000000000000000000000000000000004928 166.0
CMS2_k127_7006559_34 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000001116 145.0
CMS2_k127_7006559_35 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000001041 111.0
CMS2_k127_7006559_36 Flagellar protein YcgR - - - 0.000000000000000000006908 101.0
CMS2_k127_7006559_37 Histidine kinase - - - 0.0000000000000000004935 98.0
CMS2_k127_7006559_38 Pfam matches to PF08238.7 Sel1, and to PF08238.7 Sel1, and to PF08238.7 Sel1, and to PF08238.7 Sel1 K07126 - - 0.0000000000000001821 89.0
CMS2_k127_7006559_39 phosphorelay signal transduction system - - - 0.00000000000002006 78.0
CMS2_k127_7006559_4 Phosphate transport system permease protein K02038 - - 5.79e-237 744.0
CMS2_k127_7006559_40 - - - - 0.00000008402 61.0
CMS2_k127_7006559_5 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 2.803e-223 707.0
CMS2_k127_7006559_6 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 4.055e-221 704.0
CMS2_k127_7006559_7 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009898 599.0
CMS2_k127_7006559_8 Adenylate cyclase K05851 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0052652,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 615.0
CMS2_k127_7006559_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 482.0
CMS2_k127_722986_0 5'-nucleotidase, C-terminal domain K17224 - - 6.386e-304 939.0
CMS2_k127_722986_1 Oxidoreductase molybdopterin binding domain K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 425.0
CMS2_k127_722986_2 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 324.0
CMS2_k127_722986_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000000008439 210.0
CMS2_k127_722986_4 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06020 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 0.000000000000004927 74.0
CMS2_k127_722986_5 HDOD domain - - - 0.0003508 50.0
CMS2_k127_741398_0 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 534.0
CMS2_k127_741398_1 carbon-oxygen lyase activity, acting on polysaccharides K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 438.0
CMS2_k127_741398_10 - - - - 0.000000002486 64.0
CMS2_k127_741398_11 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000009385 57.0
CMS2_k127_741398_2 Pirin C-terminal cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 377.0
CMS2_k127_741398_3 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) (Pseudouridylate synthase) (Uracil hydrolyase). Responsible for synthesis of pseudouridine from uracil-746 in 23S ribosomal RNA and from uracil-32 in the anticodon stem and loop of transfer RNAs K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000002603 256.0
CMS2_k127_741398_4 LexA-binding, inner membrane-associated putative hydrolase K07038 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000004759 190.0
CMS2_k127_741398_5 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000001375 192.0
CMS2_k127_741398_6 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000001399 171.0
CMS2_k127_741398_7 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000000000002706 163.0
CMS2_k127_741398_8 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000007883 152.0
CMS2_k127_741398_9 Domain of unknown function DUF123 - - - 0.00000000000000000000000000000000001353 142.0
CMS2_k127_756621_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 435.0
CMS2_k127_756621_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 364.0
CMS2_k127_756621_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000003232 221.0
CMS2_k127_756621_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000001972 141.0
CMS2_k127_756621_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000007251 137.0
CMS2_k127_778964_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 499.0
CMS2_k127_778964_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 447.0
CMS2_k127_778964_2 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 353.0
CMS2_k127_778964_3 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000008997 214.0
CMS2_k127_778964_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000004636 193.0
CMS2_k127_778964_5 Forkhead associated domain - - - 0.00000000000000000000006319 106.0
CMS2_k127_812326_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001524 291.0
CMS2_k127_812326_1 Uncharacterised protein family UPF0066 - GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016426,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0089715,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001592 275.0
CMS2_k127_812326_2 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000001875 171.0
CMS2_k127_812326_3 MazG-like family - - - 0.0000000000000000000000000000000000000005272 153.0
CMS2_k127_812326_4 protein disulfide oxidoreductase activity - - - 0.000000000000000000000000001176 120.0
CMS2_k127_812326_5 Protein of unknown function (DUF3579) - - - 0.000000000000000000000000002829 113.0
CMS2_k127_910836_0 Glycyl-tRNA synthetase beta subunit K01879 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 1.348e-252 796.0
CMS2_k127_910836_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 573.0
CMS2_k127_910836_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 549.0
CMS2_k127_910836_3 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002056 272.0
CMS2_k127_910836_4 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000009482 229.0
CMS2_k127_910836_5 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896 3.5.1.44 0.00006789 49.0
CMS2_k127_991123_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008989 394.0
CMS2_k127_991123_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 343.0
CMS2_k127_991123_10 NlpC/P60 family - - - 0.0000000000000000000000000000000000001336 147.0
CMS2_k127_991123_11 Family of unknown function (DUF5329) - - - 0.00000000000000000000000000008287 119.0
CMS2_k127_991123_12 protein conserved in bacteria K09920 - - 0.0000000000000000002404 93.0
CMS2_k127_991123_13 lysine 2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000003866 88.0
CMS2_k127_991123_2 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072344,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112,GO:2000113,GO:2001124,GO:2001125 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 301.0
CMS2_k127_991123_3 tRNA synthetases class II (D, K and N) K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 308.0
CMS2_k127_991123_4 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001325 284.0
CMS2_k127_991123_5 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004042 267.0
CMS2_k127_991123_6 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003491 266.0
CMS2_k127_991123_7 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000004066 226.0
CMS2_k127_991123_8 Uncharacterised protein family (UPF0227) K07000 GO:0003674,GO:0003824,GO:0016787,GO:0016788 - 0.00000000000000000000000000000000000000000000000006424 184.0
CMS2_k127_991123_9 PFAM electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000001379 175.0
CMS2_k127_996964_0 alpha-2-macroglobulin domain protein K06894 - - 0.0 1715.0
CMS2_k127_996964_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 9.23e-239 760.0
CMS2_k127_996964_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 394.0
CMS2_k127_996964_3 Uracil DNA glycosylase superfamily - - - 0.000000000000000000000000000000000000002939 150.0
CMS2_k127_996964_4 DnaK suppressor protein K06204 - - 0.00000000000000000000000000003885 119.0