Overview

ID MAG00411
Name CMS2_bin.14
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order UBA9214
Family UBA9214
Genus UBA9214
Species UBA9214 sp029881775
Assembly information
Completeness (%) 88.5
Contamination (%) 0.3
GC content (%) 58.0
N50 (bp) 49,623
Genome size (bp) 2,225,806

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2127

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_104116_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 1.148e-213 688.0
CMS2_k127_104116_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 592.0
CMS2_k127_104116_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007514 548.0
CMS2_k127_104116_3 PFAM FxsA cytoplasmic membrane protein K07113 - - 0.0000000000000000000000000000000000002077 145.0
CMS2_k127_104116_4 Divalent ion tolerance protein K03926 - - 0.000000000000000000000000000004142 130.0
CMS2_k127_1054709_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 6.384e-239 745.0
CMS2_k127_1054709_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.372e-237 740.0
CMS2_k127_1054709_10 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 349.0
CMS2_k127_1054709_11 Lytic murein transglycosylase K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 336.0
CMS2_k127_1054709_12 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006629,GO:0006720,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050515,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901576 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 327.0
CMS2_k127_1054709_13 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 315.0
CMS2_k127_1054709_14 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 290.0
CMS2_k127_1054709_15 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001429 280.0
CMS2_k127_1054709_16 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000111 268.0
CMS2_k127_1054709_17 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003796 259.0
CMS2_k127_1054709_18 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.0000000000000000000000000000000000000000000000001229 184.0
CMS2_k127_1054709_19 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 GO:0003674,GO:0003824,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016154,GO:0016740,GO:0016757,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000000002281 169.0
CMS2_k127_1054709_2 Catalyzes cross-linking of the peptidoglycan cell wall K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 4.278e-233 742.0
CMS2_k127_1054709_20 PFAM HopJ type III effector protein - - - 0.0000000000000000000000000000000000000000000834 162.0
CMS2_k127_1054709_21 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.00000000000000000000000000000000003744 141.0
CMS2_k127_1054709_22 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000007746 132.0
CMS2_k127_1054709_23 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K14160 - - 0.0000000000000000000000000002131 121.0
CMS2_k127_1054709_24 - - - - 0.0000000000000000785 85.0
CMS2_k127_1054709_25 - - - - 0.00000000000001465 78.0
CMS2_k127_1054709_3 COG1077 Actin-like ATPase involved in cell morphogenesis K03569 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005856,GO:0005886,GO:0007049,GO:0008150,GO:0008360,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0032505,GO:0042802,GO:0043093,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051301,GO:0051302,GO:0051782,GO:0051983,GO:0065007,GO:0065008,GO:0071944 - 4.512e-194 608.0
CMS2_k127_1054709_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 527.0
CMS2_k127_1054709_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 468.0
CMS2_k127_1054709_6 Belongs to the peptidase S11 family K07258 GO:0000270,GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 457.0
CMS2_k127_1054709_7 Peptidoglycan polymerase that is essential for cell wall elongation K05837 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008360,GO:0016020,GO:0022603,GO:0022604,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 451.0
CMS2_k127_1054709_8 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 369.0
CMS2_k127_1054709_9 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 349.0
CMS2_k127_1085956_0 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 GO:0000103,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006790,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008441,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 337.0
CMS2_k127_1085956_1 Haloacid dehalogenase-like hydrolase K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000002556 271.0
CMS2_k127_1085956_2 metal cluster binding K06940 - - 0.0000000000000000000000000000000000000000000000000000000000001852 215.0
CMS2_k127_1085956_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000001615 175.0
CMS2_k127_1085956_4 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.00000000000000000000000000001771 124.0
CMS2_k127_1085956_6 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.000000126 56.0
CMS2_k127_110078_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 GO:0000302,GO:0003674,GO:0003824,GO:0004802,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006098,GO:0006139,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009635,GO:0009636,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010033,GO:0010035,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016740,GO:0016744,GO:0019219,GO:0019222,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0019842,GO:0030145,GO:0030976,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0035690,GO:0036094,GO:0036245,GO:0042221,GO:0042493,GO:0042542,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045893,GO:0045935,GO:0046483,GO:0046496,GO:0046677,GO:0046872,GO:0046914,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051156,GO:0051171,GO:0051173,GO:0051186,GO:0051252,GO:0051254,GO:0051716,GO:0055086,GO:0060255,GO:0065007,GO:0070301,GO:0070887,GO:0071236,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0072524,GO:0072747,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:1901135,GO:1901322,GO:1901360,GO:1901363,GO:1901562,GO:1901564,GO:1901654,GO:1901655,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.2.1.1 0.0 1101.0
CMS2_k127_110078_1 response regulator receiver K02487,K06596 - - 1.998e-319 1051.0
CMS2_k127_110078_10 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 569.0
CMS2_k127_110078_11 TIGRFAM dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 514.0
CMS2_k127_110078_12 chemotaxis K02660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 512.0
CMS2_k127_110078_13 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 494.0
CMS2_k127_110078_14 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 438.0
CMS2_k127_110078_15 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 433.0
CMS2_k127_110078_16 PFAM Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 410.0
CMS2_k127_110078_17 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 323.0
CMS2_k127_110078_18 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009039 290.0
CMS2_k127_110078_19 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001161 279.0
CMS2_k127_110078_2 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 2.171e-250 781.0
CMS2_k127_110078_20 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001852 274.0
CMS2_k127_110078_21 Belongs to the UPF0301 (AlgH) family K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000003716 257.0
CMS2_k127_110078_22 phosphoribosyltransferase K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000001712 248.0
CMS2_k127_110078_23 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000001013 218.0
CMS2_k127_110078_24 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000001374 207.0
CMS2_k127_110078_25 Periplasmic protein TonB links inner and outer membranes K03832 - - 0.000000000000000000000000000000000000000000000000000000009777 208.0
CMS2_k127_110078_26 response regulator receiver K02657 - - 0.00000000000000000000000000000000000000000000000000000006415 199.0
CMS2_k127_110078_27 response regulator receiver K02658 - - 0.0000000000000000000000000000000000000000000002281 169.0
CMS2_k127_110078_28 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000004707 144.0
CMS2_k127_110078_29 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000006008 138.0
CMS2_k127_110078_3 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 5.606e-225 703.0
CMS2_k127_110078_30 Two component signalling adaptor domain K02659 - - 0.00000000000000000000000000000000004197 141.0
CMS2_k127_110078_31 - - - - 0.000000000000000000000000000000008024 134.0
CMS2_k127_110078_32 NfeD-like C-terminal, partner-binding K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000009509 109.0
CMS2_k127_110078_33 PFAM nucleic acid binding, OB-fold, tRNA K02390 - - 0.00000000000000000005587 98.0
CMS2_k127_110078_34 chemotaxis signal transduction protein K06598 - - 0.0000000000000000000747 95.0
CMS2_k127_110078_35 prohibitin homologues - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000009478 86.0
CMS2_k127_110078_36 - - - - 0.00000000000001828 80.0
CMS2_k127_110078_37 PFAM Peptidase M16 K07263 - - 0.0000000009285 67.0
CMS2_k127_110078_4 Belongs to the phosphoglycerate kinase family K00927 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 2.235e-220 687.0
CMS2_k127_110078_5 serine dehydratase beta chain K01752 - 4.3.1.17 9.664e-212 665.0
CMS2_k127_110078_6 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.273e-201 634.0
CMS2_k127_110078_7 Belongs to the pyruvate kinase family K00873 GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016043,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0022607,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.40 3.195e-201 637.0
CMS2_k127_110078_8 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 610.0
CMS2_k127_110078_9 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 609.0
CMS2_k127_1104977_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1102.0
CMS2_k127_1104977_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 GO:0000819,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0022402,GO:0030541,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0098813,GO:0140097,GO:1901360 - 0.0 1018.0
CMS2_k127_1104977_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000001284 152.0
CMS2_k127_1104977_11 gag-polyprotein putative aspartyl protease K06985 - - 0.000000000000000000000000001098 119.0
CMS2_k127_1104977_12 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000561 94.0
CMS2_k127_1104977_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000004687 80.0
CMS2_k127_1104977_14 CNP1-like family - - - 0.000000000000000661 85.0
CMS2_k127_1104977_2 Cysteine-rich domain - - - 2.081e-216 679.0
CMS2_k127_1104977_3 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005968 428.0
CMS2_k127_1104977_4 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 386.0
CMS2_k127_1104977_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 319.0
CMS2_k127_1104977_6 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003299 274.0
CMS2_k127_1104977_7 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004135 242.0
CMS2_k127_1104977_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000003103 227.0
CMS2_k127_1104977_9 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000005379 212.0
CMS2_k127_1185731_0 Bacterial protein of unknown function (DUF853) K06915 - - 7.98e-202 638.0
CMS2_k127_1185731_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 609.0
CMS2_k127_1185731_10 Iron--sulfur cluster insertion protein erpA K15724 - - 0.00000000000000000000000000000000000000000000000000002264 189.0
CMS2_k127_1185731_11 Glutathione peroxidase - - - 0.000000000000000000000000000000000000000000000000001264 188.0
CMS2_k127_1185731_12 - - - - 0.000000000000000000000000000000000000000008699 154.0
CMS2_k127_1185731_13 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000001304 148.0
CMS2_k127_1185731_14 Protein of unknown function (DUF3465) - - - 0.00000000000000000000000000000000000004554 147.0
CMS2_k127_1185731_15 PFAM Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000988 135.0
CMS2_k127_1185731_16 - - - - 0.000000000000000000000000000179 124.0
CMS2_k127_1185731_17 - - - - 0.0000000000000000000000000007769 114.0
CMS2_k127_1185731_18 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000006436 100.0
CMS2_k127_1185731_19 - - - - 0.0000000000000000002448 89.0
CMS2_k127_1185731_2 Galactose-1-phosphate uridyl transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 535.0
CMS2_k127_1185731_21 - - - - 0.0000000000000005648 79.0
CMS2_k127_1185731_22 - - - - 0.00000000000001659 74.0
CMS2_k127_1185731_23 Dodecin K09165 - - 0.0000229 48.0
CMS2_k127_1185731_24 Dodecin K09165 - - 0.0004736 42.0
CMS2_k127_1185731_25 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0008146 43.0
CMS2_k127_1185731_3 Chloride channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 537.0
CMS2_k127_1185731_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 510.0
CMS2_k127_1185731_5 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 509.0
CMS2_k127_1185731_6 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 419.0
CMS2_k127_1185731_7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 389.0
CMS2_k127_1185731_8 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 280.0
CMS2_k127_1185731_9 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000963 278.0
CMS2_k127_1480970_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1390.0
CMS2_k127_1480970_1 UPF0313 protein - - - 0.0 1166.0
CMS2_k127_1480970_10 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 300.0
CMS2_k127_1480970_11 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 299.0
CMS2_k127_1480970_12 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 292.0
CMS2_k127_1480970_13 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007284 280.0
CMS2_k127_1480970_14 Permease YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001057 275.0
CMS2_k127_1480970_15 PFAM Patatin K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003497 251.0
CMS2_k127_1480970_16 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000001959 194.0
CMS2_k127_1480970_17 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000000004759 182.0
CMS2_k127_1480970_18 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000001676 175.0
CMS2_k127_1480970_19 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.000000000000000000000000000000000000000009528 160.0
CMS2_k127_1480970_2 Domain of unknown function (DUF4478) K06966 - 3.2.2.10 8.502e-228 714.0
CMS2_k127_1480970_20 - - - - 0.000000000000000000000000000000000000193 151.0
CMS2_k127_1480970_21 PFAM Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000000000000000000001017 145.0
CMS2_k127_1480970_22 PFAM Outer membrane lipoprotein Slp K07285 - - 0.00000000000000000000000000000000004702 141.0
CMS2_k127_1480970_23 Protein of unknown function (DUF2799) - - - 0.0000000000000000000000000000001206 136.0
CMS2_k127_1480970_24 RDD family - - - 0.00000000000000000000000000006484 121.0
CMS2_k127_1480970_25 - - - - 0.00000000000002935 81.0
CMS2_k127_1480970_26 Protein of unknown function (DUF2970) - - - 0.00000000007072 65.0
CMS2_k127_1480970_27 - - - - 0.0000001006 62.0
CMS2_k127_1480970_28 surface antigen - - - 0.0000003273 61.0
CMS2_k127_1480970_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 596.0
CMS2_k127_1480970_4 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 529.0
CMS2_k127_1480970_5 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 472.0
CMS2_k127_1480970_6 a CheY-like receiver domain and an HD-GYP domain K07814,K13815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 413.0
CMS2_k127_1480970_7 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 398.0
CMS2_k127_1480970_8 Histidine kinase K10715,K20974 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 332.0
CMS2_k127_1480970_9 Permease YjgP YjgQ K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 314.0
CMS2_k127_1542342_0 Amino Acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 369.0
CMS2_k127_1542342_1 kinase activity K07154 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000001991 205.0
CMS2_k127_1542342_2 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000001852 179.0
CMS2_k127_1542342_3 Subunit R is required for both nuclease and ATPase activities, but not for modification - - - 0.000000000000000000000000000000000000132 148.0
CMS2_k127_1542342_4 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000002931 144.0
CMS2_k127_1542342_5 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000000001281 59.0
CMS2_k127_1542342_6 domain, Protein - - - 0.0000006181 61.0
CMS2_k127_1583303_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.723e-285 884.0
CMS2_k127_1583303_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 2.409e-245 774.0
CMS2_k127_1583303_10 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 333.0
CMS2_k127_1583303_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 311.0
CMS2_k127_1583303_12 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 303.0
CMS2_k127_1583303_13 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003738 274.0
CMS2_k127_1583303_14 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002134,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000006328 254.0
CMS2_k127_1583303_15 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000004253 226.0
CMS2_k127_1583303_16 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000204 153.0
CMS2_k127_1583303_17 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000001955 146.0
CMS2_k127_1583303_18 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000006838 140.0
CMS2_k127_1583303_19 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000002783 132.0
CMS2_k127_1583303_2 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 8.649e-218 692.0
CMS2_k127_1583303_20 membrane transporter protein K07090 - - 0.00000000000000000000000000001974 120.0
CMS2_k127_1583303_21 - - - - 0.0000000000000000000000000008549 114.0
CMS2_k127_1583303_22 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000001823 96.0
CMS2_k127_1583303_23 Pfam Transposase IS66 - - - 0.000000000000000002161 97.0
CMS2_k127_1583303_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 6.052e-201 655.0
CMS2_k127_1583303_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930,K22478 GO:0003674,GO:0003824,GO:0003991,GO:0004042,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016407,GO:0016410,GO:0016597,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0033554,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 470.0
CMS2_k127_1583303_5 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 469.0
CMS2_k127_1583303_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 GO:0000166,GO:0003674,GO:0003824,GO:0004632,GO:0004633,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0015936,GO:0015937,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032553,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 466.0
CMS2_k127_1583303_7 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 406.0
CMS2_k127_1583303_8 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 389.0
CMS2_k127_1583303_9 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 349.0
CMS2_k127_1752199_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1529.0
CMS2_k127_1752199_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.235e-250 791.0
CMS2_k127_1752199_10 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 568.0
CMS2_k127_1752199_11 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 560.0
CMS2_k127_1752199_12 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K10941 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 544.0
CMS2_k127_1752199_13 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 521.0
CMS2_k127_1752199_14 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 GO:0001676,GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0003989,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006417,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0017148,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032787,GO:0032991,GO:0034248,GO:0034249,GO:0042759,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:0097159,GO:1901363,GO:1901576,GO:1902494,GO:1990234,GO:2000112,GO:2000113 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 452.0
CMS2_k127_1752199_15 major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 448.0
CMS2_k127_1752199_16 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 430.0
CMS2_k127_1752199_17 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 416.0
CMS2_k127_1752199_18 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004486,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0055114,GO:0071704,GO:1901360,GO:1901564 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 408.0
CMS2_k127_1752199_19 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 373.0
CMS2_k127_1752199_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.251e-238 743.0
CMS2_k127_1752199_20 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 368.0
CMS2_k127_1752199_21 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 359.0
CMS2_k127_1752199_22 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 352.0
CMS2_k127_1752199_23 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 331.0
CMS2_k127_1752199_24 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 354.0
CMS2_k127_1752199_25 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 334.0
CMS2_k127_1752199_26 Methyltransferase K18911 - 2.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 327.0
CMS2_k127_1752199_27 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 316.0
CMS2_k127_1752199_28 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009384 313.0
CMS2_k127_1752199_29 pfam mofrl K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 321.0
CMS2_k127_1752199_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0003674,GO:0003824,GO:0004044,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006520,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009064,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0034654,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.4.2.14 6.833e-238 744.0
CMS2_k127_1752199_30 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 304.0
CMS2_k127_1752199_31 COG2826 Transposase and inactivated derivatives, IS30 family K07482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 297.0
CMS2_k127_1752199_32 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 295.0
CMS2_k127_1752199_33 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 291.0
CMS2_k127_1752199_34 Belongs to the ParA family K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001288 287.0
CMS2_k127_1752199_35 Glycine zipper - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000429 261.0
CMS2_k127_1752199_36 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002069 258.0
CMS2_k127_1752199_37 signal transduction protein containing sensor and EAL domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004745 264.0
CMS2_k127_1752199_38 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000001178 242.0
CMS2_k127_1752199_39 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000002406 232.0
CMS2_k127_1752199_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 6.087e-235 741.0
CMS2_k127_1752199_40 Tfp pilus assembly protein K08086 - - 0.000000000000000000000000000000000000000000000000000000000000000008832 250.0
CMS2_k127_1752199_41 Sterol carrier protein - - - 0.0000000000000000000000000000000000000000000000000000000000001351 215.0
CMS2_k127_1752199_42 plasmid maintenance K03496 - - 0.0000000000000000000000000000000000000000000000000000000000532 211.0
CMS2_k127_1752199_43 membrane protein, required for colicin V production K03558 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009403,GO:0009404,GO:0009987,GO:0016020,GO:0019748,GO:0044237,GO:0044249,GO:0044464,GO:0044550,GO:0071944 - 0.0000000000000000000000000000000000000000000002031 172.0
CMS2_k127_1752199_44 antisigma factor binding - - - 0.0000000000000000000000000000000000000000008526 167.0
CMS2_k127_1752199_45 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000001137 155.0
CMS2_k127_1752199_46 cellulose 1,4-beta-cellobiosidase activity K01278,K01727,K03561,K12287,K21449 - 3.4.14.5,4.2.2.1 0.000000000000000000000000000000000000003872 158.0
CMS2_k127_1752199_47 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000000465 137.0
CMS2_k127_1752199_48 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000007877 140.0
CMS2_k127_1752199_49 Copper chaperone PCu(A)C K09796 - - 0.00000000000000000000000003671 113.0
CMS2_k127_1752199_5 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 7.834e-218 680.0
CMS2_k127_1752199_50 - - - - 0.0000000000000000000000432 104.0
CMS2_k127_1752199_51 Sporulation related domain K03749 - - 0.00000000000000000002663 98.0
CMS2_k127_1752199_52 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000000000005572 90.0
CMS2_k127_1752199_53 - - - - 0.0000000000000003593 87.0
CMS2_k127_1752199_54 Pentapeptide repeats (8 copies) - - - 0.0000000000000008973 83.0
CMS2_k127_1752199_55 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000005709 66.0
CMS2_k127_1752199_56 domain, Protein - - - 0.00000000001681 75.0
CMS2_k127_1752199_57 transferase activity, transferring glycosyl groups K20276 - - 0.00000000004132 74.0
CMS2_k127_1752199_58 - - - - 0.00000000006087 70.0
CMS2_k127_1752199_59 malate dehydrogenase (decarboxylating) (NAD+) activity K00027,K00029 GO:0003674,GO:0003824,GO:0004470,GO:0004471,GO:0004473,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006094,GO:0006108,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0019318,GO:0019319,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0055114,GO:0071704,GO:1901576 1.1.1.38,1.1.1.40 0.0000000001112 64.0
CMS2_k127_1752199_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 6.646e-215 677.0
CMS2_k127_1752199_60 - - - - 0.000000000379 63.0
CMS2_k127_1752199_62 - - - - 0.00000002097 57.0
CMS2_k127_1752199_63 - - - - 0.00000002458 59.0
CMS2_k127_1752199_66 Protein of unknown function (DUF3106) - - - 0.0000006769 56.0
CMS2_k127_1752199_67 Multicopper oxidase K00368,K22348,K22349 - 1.16.3.3,1.7.2.1 0.00001401 47.0
CMS2_k127_1752199_69 - - - - 0.00002387 48.0
CMS2_k127_1752199_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 608.0
CMS2_k127_1752199_70 - - - - 0.0001691 51.0
CMS2_k127_1752199_8 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 593.0
CMS2_k127_1752199_9 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 584.0
CMS2_k127_1820783_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.0 1071.0
CMS2_k127_1820783_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.153e-229 717.0
CMS2_k127_1820783_10 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007142 244.0
CMS2_k127_1820783_11 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006658 229.0
CMS2_k127_1820783_12 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000001185 228.0
CMS2_k127_1820783_13 - - - - 0.0000000000000000000000000000000000000000000000000000007225 203.0
CMS2_k127_1820783_14 eight transmembrane protein EpsH - - - 0.000000000000000000000000000000000000000000000000000001531 210.0
CMS2_k127_1820783_15 - - - - 0.00000000000000000000000000000000000001001 148.0
CMS2_k127_1820783_16 - - - - 0.0000000000000000000000000000000000001997 151.0
CMS2_k127_1820783_17 - - - - 0.00000000000000000009274 96.0
CMS2_k127_1820783_18 - - - - 0.00000000000006529 79.0
CMS2_k127_1820783_19 PEP-CTERM motif - - - 0.0007648 49.0
CMS2_k127_1820783_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 2.968e-198 626.0
CMS2_k127_1820783_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 569.0
CMS2_k127_1820783_4 Sigma-54 interaction domain K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 466.0
CMS2_k127_1820783_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 443.0
CMS2_k127_1820783_6 Polysaccharide chain length determinant protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 340.0
CMS2_k127_1820783_7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 305.0
CMS2_k127_1820783_8 xylanase chitin deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009863 267.0
CMS2_k127_1820783_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004843 256.0
CMS2_k127_1974536_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1154.0
CMS2_k127_1974536_1 Citrate transporter - - - 0.0 1003.0
CMS2_k127_1974536_10 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 524.0
CMS2_k127_1974536_11 molecular chaperone K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 481.0
CMS2_k127_1974536_12 Belongs to the class I fructose-bisphosphate aldolase family K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009731 471.0
CMS2_k127_1974536_13 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 460.0
CMS2_k127_1974536_14 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 GO:0003674,GO:0003824,GO:0004014,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 429.0
CMS2_k127_1974536_15 SMART AAA ATPase K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 442.0
CMS2_k127_1974536_16 protein conserved in bacteria K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 436.0
CMS2_k127_1974536_17 PFAM MscS Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 405.0
CMS2_k127_1974536_18 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 382.0
CMS2_k127_1974536_19 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 365.0
CMS2_k127_1974536_2 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 4.495e-267 845.0
CMS2_k127_1974536_20 COG0209 Ribonucleotide reductase, alpha subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 354.0
CMS2_k127_1974536_21 HAD-hyrolase-like K01091 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0031404,GO:0033554,GO:0034641,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 346.0
CMS2_k127_1974536_22 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 348.0
CMS2_k127_1974536_23 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 349.0
CMS2_k127_1974536_24 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 327.0
CMS2_k127_1974536_25 TIGRFAM cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 318.0
CMS2_k127_1974536_26 PFAM Cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 317.0
CMS2_k127_1974536_27 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 302.0
CMS2_k127_1974536_28 Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002905 282.0
CMS2_k127_1974536_29 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000584 267.0
CMS2_k127_1974536_3 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 2.479e-258 801.0
CMS2_k127_1974536_30 PFAM Sulphatase-modifying factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001971 290.0
CMS2_k127_1974536_31 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007263 285.0
CMS2_k127_1974536_32 Yip1 domain - GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000003119 237.0
CMS2_k127_1974536_33 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000003412 244.0
CMS2_k127_1974536_34 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000459 225.0
CMS2_k127_1974536_35 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000000006562 227.0
CMS2_k127_1974536_36 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000005756 213.0
CMS2_k127_1974536_37 part of a sulfur-relay system K11179 - - 0.00000000000000000000000000000000000000000000000000000000062 203.0
CMS2_k127_1974536_38 PFAM tRNA rRNA methyltransferase (SpoU) - - - 0.0000000000000000000000000000000000000000000000000000008119 201.0
CMS2_k127_1974536_39 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000008214 202.0
CMS2_k127_1974536_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 2.561e-250 799.0
CMS2_k127_1974536_40 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000001945 190.0
CMS2_k127_1974536_41 OmpW family K07275 - - 0.00000000000000000000000000000000000000000000000000004773 194.0
CMS2_k127_1974536_42 surface antigen - - - 0.0000000000000000000000000000000000000000000000001751 184.0
CMS2_k127_1974536_43 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000002417 179.0
CMS2_k127_1974536_44 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000001454 150.0
CMS2_k127_1974536_45 protein conserved in bacteria K09926 - - 0.0000000000000000000000000000000000731 139.0
CMS2_k127_1974536_46 Belongs to the bacterial histone-like protein family - - - 0.000000000000000000000000000000001551 133.0
CMS2_k127_1974536_47 MerR HTH family regulatory protein K18997 - - 0.000000000000000000000000000000007978 130.0
CMS2_k127_1974536_48 Hemimethylated DNA-binding protein YccV like K11940 - - 0.00000000000000000000000000000001227 134.0
CMS2_k127_1974536_49 TIGRFAM Pilus modification type IV, PilV K02671 - - 0.00000000000000000000000000000002896 134.0
CMS2_k127_1974536_5 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 1.163e-231 731.0
CMS2_k127_1974536_50 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.0000000000000000000000000000001879 126.0
CMS2_k127_1974536_51 Tellurite resistance protein TerB - - - 0.0000000000000000000000000006644 118.0
CMS2_k127_1974536_52 Peptidyl-prolyl cis-trans K03775 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010467,GO:0016151,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0022417,GO:0031647,GO:0035821,GO:0036211,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043963,GO:0044003,GO:0044068,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0044501,GO:0046872,GO:0046914,GO:0050821,GO:0050896,GO:0050897,GO:0051082,GO:0051604,GO:0051701,GO:0051704,GO:0051817,GO:0052027,GO:0052250,GO:0065007,GO:0065008,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000002582 114.0
CMS2_k127_1974536_53 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.00000000000000000000000003634 115.0
CMS2_k127_1974536_54 Type II transport protein GspH K08084 - - 0.0000000000000000000000003732 112.0
CMS2_k127_1974536_55 - - - - 0.000000000000000000000008283 104.0
CMS2_k127_1974536_56 - - - - 0.00000000000000000000001696 105.0
CMS2_k127_1974536_57 Type II secretion system protein B - - - 0.000000000000000002486 93.0
CMS2_k127_1974536_58 - - - - 0.000000000000000004218 84.0
CMS2_k127_1974536_59 Protein of unknown function (DUF2788) - - - 0.000000000000001316 78.0
CMS2_k127_1974536_6 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.316e-222 699.0
CMS2_k127_1974536_60 - - - - 0.00000000000003673 83.0
CMS2_k127_1974536_61 Cytochrome oxidase maturation protein - - - 0.0000000000001108 77.0
CMS2_k127_1974536_62 - - - - 0.0000000000005915 75.0
CMS2_k127_1974536_63 Belongs to the ompA family K03286 - - 0.00000000004691 66.0
CMS2_k127_1974536_64 Conserved TM helix - - - 0.00000000009285 64.0
CMS2_k127_1974536_65 Cbb3-type cytochrome oxidase K00407 - - 0.0000000001942 63.0
CMS2_k127_1974536_67 alpha beta - - - 0.000000001079 63.0
CMS2_k127_1974536_68 Trypsin-like serine protease - - - 0.000000001183 72.0
CMS2_k127_1974536_69 Type IV pilus assembly protein PilX C-term K02673 - - 0.000000001478 66.0
CMS2_k127_1974536_7 COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 9.825e-221 726.0
CMS2_k127_1974536_70 COG0607 Rhodanese-related sulfurtransferase - - - 0.000000005694 61.0
CMS2_k127_1974536_71 HDOD domain - - - 0.0000001945 58.0
CMS2_k127_1974536_72 Signal transduction protein K01915 - 6.3.1.2 0.00001817 50.0
CMS2_k127_1974536_8 DUF1704 - - - 5.599e-206 652.0
CMS2_k127_1974536_9 TIGRFAM cytochrome c oxidase accessory protein FixG - - - 2.704e-195 618.0
CMS2_k127_2118557_0 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003841 284.0
CMS2_k127_2118557_1 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000000009713 101.0
CMS2_k127_2118557_2 Serine aminopeptidase, S33 - - - 0.0003314 43.0
CMS2_k127_2142097_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 465.0
CMS2_k127_2142097_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 351.0
CMS2_k127_2142097_2 Competence protein - - - 0.000000000000000000000000000000000000000000000000000000000001281 218.0
CMS2_k127_2142097_3 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008813,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016833,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.3.40 0.000000000000000000000000000000000000000409 155.0
CMS2_k127_2151386_0 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 - 4.1.1.38 0.0 1734.0
CMS2_k127_2151386_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0 1064.0
CMS2_k127_2151386_10 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 539.0
CMS2_k127_2151386_11 Dehydrogenase E1 component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 506.0
CMS2_k127_2151386_12 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 486.0
CMS2_k127_2151386_13 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 453.0
CMS2_k127_2151386_14 Cytosol aminopeptidase family, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 450.0
CMS2_k127_2151386_15 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 373.0
CMS2_k127_2151386_16 Sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 372.0
CMS2_k127_2151386_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 350.0
CMS2_k127_2151386_18 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 330.0
CMS2_k127_2151386_19 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 298.0
CMS2_k127_2151386_2 GTP-binding protein TypA K06207 - - 3.465e-311 962.0
CMS2_k127_2151386_20 CorA-like Mg2+ transporter protein K16074 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 300.0
CMS2_k127_2151386_21 May be involved in recombination K03554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002044 284.0
CMS2_k127_2151386_22 Glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002905 280.0
CMS2_k127_2151386_23 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009393 254.0
CMS2_k127_2151386_24 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000004429 223.0
CMS2_k127_2151386_25 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000000008553 184.0
CMS2_k127_2151386_26 - - - - 0.000000000000000000000000000000000000000000000000001096 188.0
CMS2_k127_2151386_27 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000003853 169.0
CMS2_k127_2151386_28 COG1186 Protein chain release factor B K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000000000000000001458 165.0
CMS2_k127_2151386_29 aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000001507 167.0
CMS2_k127_2151386_3 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 2.752e-261 816.0
CMS2_k127_2151386_30 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.00000000000000000000000000000000000000000002328 169.0
CMS2_k127_2151386_31 CbiX K03794 - 4.99.1.4 0.000000000000000000000000000000000007645 139.0
CMS2_k127_2151386_32 Cold shock K03704 - - 0.000000000000000000000000000001594 121.0
CMS2_k127_2151386_33 - - - - 0.00000000000000000000000002484 114.0
CMS2_k127_2151386_34 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000001263 91.0
CMS2_k127_2151386_35 - - - - 0.000000000000000001599 87.0
CMS2_k127_2151386_36 - - - - 0.00000002815 59.0
CMS2_k127_2151386_37 - - - - 0.00004862 52.0
CMS2_k127_2151386_4 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 2.391e-239 742.0
CMS2_k127_2151386_5 ABC transporter K15738 - - 2.179e-231 734.0
CMS2_k127_2151386_6 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 9.925e-211 666.0
CMS2_k127_2151386_7 Diguanylate cyclase - - - 1.135e-194 643.0
CMS2_k127_2151386_8 PFAM sodium alanine symporter K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 609.0
CMS2_k127_2151386_9 Transketolase, pyrimidine binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 543.0
CMS2_k127_2266506_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000003119 73.0
CMS2_k127_2276472_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 4557.0
CMS2_k127_2276472_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1486.0
CMS2_k127_2276472_10 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.121e-243 779.0
CMS2_k127_2276472_100 TonB C terminal K03832 - - 0.00000000000000000000000003258 119.0
CMS2_k127_2276472_101 - - - - 0.000000000000000000000000121 110.0
CMS2_k127_2276472_102 Sulfotransferase domain - - - 0.000000000000000000000002913 114.0
CMS2_k127_2276472_103 PFAM Sulfotransferase domain - - - 0.0000000000000000000001098 108.0
CMS2_k127_2276472_104 Protein of unknown function (DUF1488) - - - 0.0000000000000000000141 94.0
CMS2_k127_2276472_105 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000001554 83.0
CMS2_k127_2276472_106 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000006197 85.0
CMS2_k127_2276472_107 part of a sulfur-relay system K11179 - - 0.0000000000000002993 83.0
CMS2_k127_2276472_108 TIGRFAM Diguanylate cyclase - - - 0.000000000003674 70.0
CMS2_k127_2276472_109 Protein of unknown function (DUF721) - - - 0.00000000001065 71.0
CMS2_k127_2276472_11 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 9.842e-237 744.0
CMS2_k127_2276472_110 - K06950 - - 0.00000000003123 66.0
CMS2_k127_2276472_111 Outer membrane protein beta-barrel domain - - - 0.00001538 55.0
CMS2_k127_2276472_113 SH3 and PX - - - 0.0002392 47.0
CMS2_k127_2276472_12 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 3.222e-219 685.0
CMS2_k127_2276472_13 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 4.242e-218 689.0
CMS2_k127_2276472_14 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.57e-199 637.0
CMS2_k127_2276472_15 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.491e-198 631.0
CMS2_k127_2276472_16 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 578.0
CMS2_k127_2276472_17 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 580.0
CMS2_k127_2276472_18 PFAM response regulator receiver K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 576.0
CMS2_k127_2276472_19 HflC and HflK could regulate a protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 561.0
CMS2_k127_2276472_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1410.0
CMS2_k127_2276472_20 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 552.0
CMS2_k127_2276472_21 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 538.0
CMS2_k127_2276472_22 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 534.0
CMS2_k127_2276472_23 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 527.0
CMS2_k127_2276472_24 COG0714 MoxR-like ATPases K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 522.0
CMS2_k127_2276472_25 Type II secretory pathway, component PulF K02653 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008104,GO:0008150,GO:0009297,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0016020,GO:0016043,GO:0022607,GO:0030030,GO:0030031,GO:0032940,GO:0033036,GO:0042886,GO:0043711,GO:0044085,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0098776 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 520.0
CMS2_k127_2276472_26 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 511.0
CMS2_k127_2276472_27 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 488.0
CMS2_k127_2276472_28 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 490.0
CMS2_k127_2276472_29 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 490.0
CMS2_k127_2276472_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1292.0
CMS2_k127_2276472_30 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008764,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 491.0
CMS2_k127_2276472_31 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 491.0
CMS2_k127_2276472_32 major facilitator superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 458.0
CMS2_k127_2276472_33 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 441.0
CMS2_k127_2276472_34 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 434.0
CMS2_k127_2276472_35 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 422.0
CMS2_k127_2276472_36 Histidine kinase K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 421.0
CMS2_k127_2276472_37 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 409.0
CMS2_k127_2276472_38 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 400.0
CMS2_k127_2276472_39 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 402.0
CMS2_k127_2276472_4 5'-nucleotidase, C-terminal domain K17224 - - 3.836e-313 969.0
CMS2_k127_2276472_40 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 389.0
CMS2_k127_2276472_41 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 387.0
CMS2_k127_2276472_42 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 397.0
CMS2_k127_2276472_43 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 381.0
CMS2_k127_2276472_44 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 386.0
CMS2_k127_2276472_45 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 381.0
CMS2_k127_2276472_46 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 379.0
CMS2_k127_2276472_47 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 382.0
CMS2_k127_2276472_48 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 372.0
CMS2_k127_2276472_49 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 368.0
CMS2_k127_2276472_5 Exporters of the RND superfamily K07003 - - 3.233e-312 977.0
CMS2_k127_2276472_50 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 368.0
CMS2_k127_2276472_51 C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 364.0
CMS2_k127_2276472_52 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 367.0
CMS2_k127_2276472_53 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 377.0
CMS2_k127_2276472_54 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 348.0
CMS2_k127_2276472_55 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 353.0
CMS2_k127_2276472_56 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 339.0
CMS2_k127_2276472_57 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 344.0
CMS2_k127_2276472_58 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 338.0
CMS2_k127_2276472_59 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 327.0
CMS2_k127_2276472_6 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.378e-299 927.0
CMS2_k127_2276472_60 ZIP Zinc transporter K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 319.0
CMS2_k127_2276472_61 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 309.0
CMS2_k127_2276472_62 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 306.0
CMS2_k127_2276472_63 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 303.0
CMS2_k127_2276472_64 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 306.0
CMS2_k127_2276472_65 glycosyl transferase group 1 K13668 - 2.4.1.346 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 309.0
CMS2_k127_2276472_66 ATPases associated with a variety of cellular activities K02003 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 295.0
CMS2_k127_2276472_67 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 291.0
CMS2_k127_2276472_68 methyltransferase activity K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003324 275.0
CMS2_k127_2276472_69 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005703 270.0
CMS2_k127_2276472_7 COG0514 Superfamily II DNA helicase K03654 - 3.6.4.12 9.864e-295 914.0
CMS2_k127_2276472_70 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006798 268.0
CMS2_k127_2276472_71 Oxygen tolerance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004623 270.0
CMS2_k127_2276472_72 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002904 249.0
CMS2_k127_2276472_73 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000002823 226.0
CMS2_k127_2276472_74 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000342 229.0
CMS2_k127_2276472_75 Belongs to the UPF0178 family K09768 - - 0.00000000000000000000000000000000000000000000000000000000000003198 217.0
CMS2_k127_2276472_76 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000089 229.0
CMS2_k127_2276472_77 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000002964 207.0
CMS2_k127_2276472_78 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000003482 211.0
CMS2_k127_2276472_79 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000009968 193.0
CMS2_k127_2276472_8 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 4.131e-284 894.0
CMS2_k127_2276472_80 - - - - 0.0000000000000000000000000000000000000000000000000001261 192.0
CMS2_k127_2276472_81 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000000000000000000002635 189.0
CMS2_k127_2276472_82 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000004182 189.0
CMS2_k127_2276472_83 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000005155 185.0
CMS2_k127_2276472_84 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000004359 181.0
CMS2_k127_2276472_85 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000006077 177.0
CMS2_k127_2276472_86 Tol-Pal system-associated acyl-CoA thioesterase K07107 - - 0.00000000000000000000000000000000000000000000002266 175.0
CMS2_k127_2276472_87 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000001085 170.0
CMS2_k127_2276472_88 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000006281 166.0
CMS2_k127_2276472_89 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000009221 162.0
CMS2_k127_2276472_9 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 1.606e-245 771.0
CMS2_k127_2276472_90 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000000000000000000000000000001503 157.0
CMS2_k127_2276472_91 Pfam Tetratricopeptide K07114 - - 0.000000000000000000000000000000000000005143 164.0
CMS2_k127_2276472_92 - - - - 0.000000000000000000000000000000000009673 137.0
CMS2_k127_2276472_93 Sulphur oxidation protein SoxZ K17227 - - 0.00000000000000000000000000000000001626 137.0
CMS2_k127_2276472_94 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000002512 135.0
CMS2_k127_2276472_95 Domain of unknown function (DUF4381) - - - 0.00000000000000000000000000000000006194 141.0
CMS2_k127_2276472_96 Cytochrome c K17223 - - 0.0000000000000000000000000000007505 125.0
CMS2_k127_2276472_97 cold-shock protein K03704 - - 0.00000000000000000000000000001298 119.0
CMS2_k127_2276472_98 Putative regulatory protein - - - 0.0000000000000000000000000000236 119.0
CMS2_k127_2276472_99 Pfam Glycosyl transferase family 2 - - - 0.0000000000000000000000000001159 130.0
CMS2_k127_2339304_0 Oxidoreductase molybdopterin binding domain K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 292.0
CMS2_k127_2339304_1 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002075 261.0
CMS2_k127_2339304_2 SnoaL-like domain K06893 - - 0.00000000000000000000000000002865 121.0
CMS2_k127_2339304_3 - - - - 0.00000000000005738 73.0
CMS2_k127_2339304_4 - - - - 0.00000000004796 67.0
CMS2_k127_2408721_0 chondroitin AC lyase activity K00694,K01210,K03292 - 2.4.1.12,3.2.1.58 0.0 1243.0
CMS2_k127_2408721_1 Proton-conducting membrane transporter K05568 - - 1.487e-321 989.0
CMS2_k127_2408721_10 COG2111 Multisubunit Na H antiporter, MnhB subunit K05566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 316.0
CMS2_k127_2408721_11 COG1943 Transposase and inactivated derivatives K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003616 250.0
CMS2_k127_2408721_12 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.00000000000000000000000000000000000000000000000000000000001977 207.0
CMS2_k127_2408721_13 Na+/H+ ion antiporter subunit K05569 - - 0.00000000000000000000000000000000000000000000000000000000002011 209.0
CMS2_k127_2408721_14 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000001749 206.0
CMS2_k127_2408721_15 PFAM Na H antiporter MnhB subunit-related protein K05566 - - 0.000000000000000000000000000000000000000000000000818 178.0
CMS2_k127_2408721_16 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.00000000000000000000000000000000003569 141.0
CMS2_k127_2408721_17 Na+/H+ antiporter subunit K05571 - - 0.000000000000000000000000000000001095 132.0
CMS2_k127_2408721_18 - - - - 0.0000000000000000000000000003745 121.0
CMS2_k127_2408721_19 - - - - 0.000000000000000000000006737 104.0
CMS2_k127_2408721_2 Proton-conducting membrane transporter K05568 - - 1.192e-261 812.0
CMS2_k127_2408721_20 COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.000000000000000000000007601 104.0
CMS2_k127_2408721_21 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 0.00000000000000362 76.0
CMS2_k127_2408721_22 Phage integrase family - - - 0.000008741 49.0
CMS2_k127_2408721_3 Proton-conducting membrane transporter K05568 - - 3.939e-245 764.0
CMS2_k127_2408721_4 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 583.0
CMS2_k127_2408721_5 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 503.0
CMS2_k127_2408721_6 Alanine racemase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 469.0
CMS2_k127_2408721_7 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 466.0
CMS2_k127_2408721_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 360.0
CMS2_k127_2408721_9 -transporter K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 337.0
CMS2_k127_2442924_0 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 0.0 1042.0
CMS2_k127_2442924_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 1.69e-321 994.0
CMS2_k127_2442924_10 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 589.0
CMS2_k127_2442924_11 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 561.0
CMS2_k127_2442924_12 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 544.0
CMS2_k127_2442924_13 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 538.0
CMS2_k127_2442924_14 Na Pi-cotransporter family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 526.0
CMS2_k127_2442924_15 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 471.0
CMS2_k127_2442924_16 COG1566 Multidrug resistance efflux pump K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 432.0
CMS2_k127_2442924_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 379.0
CMS2_k127_2442924_18 ydiK promoter presents a PurR sequence, suggesting that its expression is purine-regulated - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 379.0
CMS2_k127_2442924_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 374.0
CMS2_k127_2442924_2 4Fe-4S dicluster domain - - - 9.13e-277 856.0
CMS2_k127_2442924_20 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 357.0
CMS2_k127_2442924_21 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 357.0
CMS2_k127_2442924_22 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 333.0
CMS2_k127_2442924_23 Protein of unknown function (DUF2955) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 337.0
CMS2_k127_2442924_24 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 329.0
CMS2_k127_2442924_25 PFAM NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 319.0
CMS2_k127_2442924_26 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 304.0
CMS2_k127_2442924_27 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 304.0
CMS2_k127_2442924_28 helix_turn_helix, Lux Regulon K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 301.0
CMS2_k127_2442924_29 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 301.0
CMS2_k127_2442924_3 COG3901 Regulator of nitric oxide reductase transcription K19339 - - 3.687e-257 813.0
CMS2_k127_2442924_30 uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 287.0
CMS2_k127_2442924_31 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 301.0
CMS2_k127_2442924_32 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992,K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001138 278.0
CMS2_k127_2442924_33 Two component transcriptional regulator, LuxR family K07689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002912 261.0
CMS2_k127_2442924_34 TIGRFAM CRISPR-associated protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007489 260.0
CMS2_k127_2442924_35 PKHD-type hydroxylase K07336 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003135 256.0
CMS2_k127_2442924_36 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003146 258.0
CMS2_k127_2442924_37 conserved protein involved in intracellular sulfur reduction K07235 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.000000000000000000000000000000000000000000000000000000000000000000000001654 246.0
CMS2_k127_2442924_38 Belongs to the DsrF TusC family K07236 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.000000000000000000000000000000000000000000000000000000000000000000000002419 245.0
CMS2_k127_2442924_39 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000001399 223.0
CMS2_k127_2442924_4 reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.044e-245 762.0
CMS2_k127_2442924_40 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000002 206.0
CMS2_k127_2442924_41 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000000000000000000000002548 205.0
CMS2_k127_2442924_42 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000003106 199.0
CMS2_k127_2442924_43 CYTH K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000001848 190.0
CMS2_k127_2442924_44 (twin-arginine translocation) pathway signal - - - 0.000000000000000000000000000000000000000000000002472 179.0
CMS2_k127_2442924_45 - - - - 0.000000000000000000000000000000000000000000000003957 186.0
CMS2_k127_2442924_46 - - - - 0.000000000000000000000000000000000000000001159 162.0
CMS2_k127_2442924_47 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000000006055 156.0
CMS2_k127_2442924_48 - - - - 0.0000000000000000000000000000000000007721 145.0
CMS2_k127_2442924_49 tRNA wobble position uridine thiolation K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.000000000000000000000000000000000002215 142.0
CMS2_k127_2442924_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 3.554e-235 744.0
CMS2_k127_2442924_50 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000005372 144.0
CMS2_k127_2442924_51 - - - - 0.0000000000000000000000000000000009043 136.0
CMS2_k127_2442924_52 Ion channel - - - 0.000000000000000000000000000000001825 136.0
CMS2_k127_2442924_53 - - - - 0.0000000000000000000000000000009971 130.0
CMS2_k127_2442924_54 - - - - 0.00000000000000000000000000000483 123.0
CMS2_k127_2442924_55 Peptidase S24-like - - - 0.00000000000000000000000000004441 119.0
CMS2_k127_2442924_56 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000008603 117.0
CMS2_k127_2442924_57 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000002069 117.0
CMS2_k127_2442924_58 - - - - 0.00000000000000000000001888 100.0
CMS2_k127_2442924_59 Rubrerythrin - - - 0.000000000000000000005389 104.0
CMS2_k127_2442924_6 reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 1.792e-225 700.0
CMS2_k127_2442924_60 SpoIIAA-like - - - 0.00000000000000000002414 94.0
CMS2_k127_2442924_61 - - - - 0.0000000000000000003599 89.0
CMS2_k127_2442924_64 Domain of unknown function (DUF4136) - - - 0.00000007837 63.0
CMS2_k127_2442924_7 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 1.325e-198 629.0
CMS2_k127_2442924_8 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 597.0
CMS2_k127_2442924_9 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 597.0
CMS2_k127_2590537_0 DNA polymerase X family K02347 - - 1.44e-253 793.0
CMS2_k127_2590537_1 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 578.0
CMS2_k127_2590537_10 Hydrogenase maturation protease - - - 0.00000000000000003073 88.0
CMS2_k127_2590537_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000003778 56.0
CMS2_k127_2590537_14 - - - - 0.00003428 49.0
CMS2_k127_2590537_15 - - - - 0.0008914 51.0
CMS2_k127_2590537_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 536.0
CMS2_k127_2590537_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 498.0
CMS2_k127_2590537_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 460.0
CMS2_k127_2590537_5 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K16951 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 347.0
CMS2_k127_2590537_6 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 340.0
CMS2_k127_2590537_7 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002494 256.0
CMS2_k127_2590537_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000002911 245.0
CMS2_k127_2590537_9 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000001226 150.0
CMS2_k127_2742635_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1131.0
CMS2_k127_2742635_1 peptidase K01414 - 3.4.24.70 1.005e-307 956.0
CMS2_k127_2742635_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 444.0
CMS2_k127_2742635_11 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 405.0
CMS2_k127_2742635_12 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 400.0
CMS2_k127_2742635_13 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006418,GO:0006431,GO:0006464,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019752,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 385.0
CMS2_k127_2742635_14 Bile acid sodium symporter K03453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 368.0
CMS2_k127_2742635_15 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 356.0
CMS2_k127_2742635_16 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 333.0
CMS2_k127_2742635_17 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 333.0
CMS2_k127_2742635_18 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 325.0
CMS2_k127_2742635_19 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 289.0
CMS2_k127_2742635_2 signal transduction histidine kinase - - - 5.482e-216 693.0
CMS2_k127_2742635_20 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002593 282.0
CMS2_k127_2742635_21 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0000105,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003807 269.0
CMS2_k127_2742635_22 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000005273 254.0
CMS2_k127_2742635_23 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0009987,GO:0016043,GO:0022607,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000006066 236.0
CMS2_k127_2742635_24 Pfam Rhodanese-like - - - 0.00000000000000000000000000000000000000000000000000000000000004368 216.0
CMS2_k127_2742635_25 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000002318 214.0
CMS2_k127_2742635_26 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000003226 191.0
CMS2_k127_2742635_27 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000003815 184.0
CMS2_k127_2742635_28 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000445 179.0
CMS2_k127_2742635_29 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000000000004299 173.0
CMS2_k127_2742635_3 PFAM TrkA-N domain K03499 - - 5.287e-215 675.0
CMS2_k127_2742635_30 phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.00000000000000000000000000000000000000002173 155.0
CMS2_k127_2742635_31 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03767 - 5.2.1.8 0.00000000000000000000000000000000002717 154.0
CMS2_k127_2742635_32 GGDEF domain K03320,K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000001711 134.0
CMS2_k127_2742635_33 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000001503 123.0
CMS2_k127_2742635_34 Tetratricopeptide repeat - - - 0.00000000000000000000000002174 116.0
CMS2_k127_2742635_35 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000005702 99.0
CMS2_k127_2742635_36 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 GO:0002790,GO:0003674,GO:0005215,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705 - 0.00000000000000001475 84.0
CMS2_k127_2742635_37 domain protein - - - 0.0000000000000002185 93.0
CMS2_k127_2742635_38 Putative diguanylate phosphodiesterase - - - 0.000000000006074 68.0
CMS2_k127_2742635_39 Diguanylate cyclase - - - 0.0000000135 62.0
CMS2_k127_2742635_4 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 1.899e-213 672.0
CMS2_k127_2742635_5 response regulator receiver K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 578.0
CMS2_k127_2742635_6 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 537.0
CMS2_k127_2742635_7 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 490.0
CMS2_k127_2742635_8 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 488.0
CMS2_k127_2742635_9 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007415 462.0
CMS2_k127_2774397_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 4.935e-273 851.0
CMS2_k127_2774397_1 Sporulation related domain - - - 0.0000000000000000000000000000001319 131.0
CMS2_k127_2807441_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1171.0
CMS2_k127_2807441_1 PFAM Magnesium chelatase, ChlI subunit K07391 - - 1.259e-204 647.0
CMS2_k127_2807441_2 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 596.0
CMS2_k127_2807441_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 484.0
CMS2_k127_2807441_4 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050355 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 287.0
CMS2_k127_2807441_5 - - - - 0.00000000000000000000000000000000000000000002196 167.0
CMS2_k127_2807441_6 cytochrome c5 - - - 0.000000000000000000000000000000000744 136.0
CMS2_k127_2807441_7 - - - - 0.00000000000000000000000000000003513 130.0
CMS2_k127_2807441_8 GGDEF domain - - - 0.0000000000000000000002858 98.0
CMS2_k127_2807441_9 - - - - 0.0000695 46.0
CMS2_k127_2906343_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1017.0
CMS2_k127_2906343_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.68e-294 921.0
CMS2_k127_2906343_10 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.378e-207 654.0
CMS2_k127_2906343_11 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.44e-202 639.0
CMS2_k127_2906343_12 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 596.0
CMS2_k127_2906343_13 associated with various cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 593.0
CMS2_k127_2906343_14 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 595.0
CMS2_k127_2906343_15 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 578.0
CMS2_k127_2906343_16 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 578.0
CMS2_k127_2906343_17 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 558.0
CMS2_k127_2906343_18 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 572.0
CMS2_k127_2906343_19 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 551.0
CMS2_k127_2906343_2 Molecular chaperone. Has ATPase activity K04079 - - 3.341e-281 876.0
CMS2_k127_2906343_20 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 524.0
CMS2_k127_2906343_21 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 520.0
CMS2_k127_2906343_22 Putative metallopeptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 520.0
CMS2_k127_2906343_23 4Fe-4S dicluster domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 514.0
CMS2_k127_2906343_24 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 509.0
CMS2_k127_2906343_25 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 492.0
CMS2_k127_2906343_26 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 479.0
CMS2_k127_2906343_27 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 479.0
CMS2_k127_2906343_28 Belongs to the UPF0176 family K07146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 466.0
CMS2_k127_2906343_29 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 462.0
CMS2_k127_2906343_3 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0050896,GO:0051604,GO:0051716,GO:0070417,GO:0071704,GO:0097159,GO:0097367,GO:0097428,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 1.559e-276 862.0
CMS2_k127_2906343_30 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K08692 - 6.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 455.0
CMS2_k127_2906343_31 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 464.0
CMS2_k127_2906343_32 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 449.0
CMS2_k127_2906343_33 PFAM LppC K07121 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 454.0
CMS2_k127_2906343_34 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 421.0
CMS2_k127_2906343_35 COG0277 FAD FMN-containing dehydrogenases K11472 GO:0003674,GO:0003824,GO:0006066,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009441,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0017144,GO:0019154,GO:0019752,GO:0032787,GO:0034308,GO:0034310,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046164,GO:0046296,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575,GO:1901615,GO:1901616 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 394.0
CMS2_k127_2906343_36 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 376.0
CMS2_k127_2906343_37 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 364.0
CMS2_k127_2906343_38 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 353.0
CMS2_k127_2906343_39 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008033,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016070,GO:0016740,GO:0016765,GO:0019222,GO:0031323,GO:0031326,GO:0032268,GO:0033554,GO:0034248,GO:0034470,GO:0034605,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043555,GO:0044237,GO:0044238,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051246,GO:0051716,GO:0052381,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1990497,GO:2000112,GO:2000765 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 353.0
CMS2_k127_2906343_4 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 2.859e-274 882.0
CMS2_k127_2906343_40 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0008152,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0016491,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0055114,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 340.0
CMS2_k127_2906343_41 Belongs to the RNA methyltransferase TrmD family K00554 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 329.0
CMS2_k127_2906343_42 COG2897 Rhodanese-related sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 327.0
CMS2_k127_2906343_43 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 325.0
CMS2_k127_2906343_44 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 304.0
CMS2_k127_2906343_45 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008783 276.0
CMS2_k127_2906343_46 Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008698 269.0
CMS2_k127_2906343_47 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000001421 263.0
CMS2_k127_2906343_48 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000000003392 244.0
CMS2_k127_2906343_49 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000003051 228.0
CMS2_k127_2906343_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 9.877e-239 752.0
CMS2_k127_2906343_50 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000008385 234.0
CMS2_k127_2906343_51 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.000000000000000000000000000000000000000000000000000000000000033 215.0
CMS2_k127_2906343_52 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000000001176 208.0
CMS2_k127_2906343_53 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000001001 209.0
CMS2_k127_2906343_54 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000000000000000000008605 210.0
CMS2_k127_2906343_55 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 - - 0.000000000000000000000000000000000000000000000000000000001522 203.0
CMS2_k127_2906343_56 pfam nudix K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000011 200.0
CMS2_k127_2906343_57 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000137 199.0
CMS2_k127_2906343_58 AMP-binding enzyme K00666 - - 0.00000000000000000000000000000000000000000000000000000158 205.0
CMS2_k127_2906343_59 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000003226 194.0
CMS2_k127_2906343_6 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 9.226e-236 733.0
CMS2_k127_2906343_60 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000827 189.0
CMS2_k127_2906343_61 Belongs to the HesB IscA family K05997,K13628 - - 0.0000000000000000000000000000000000000000000000000001059 186.0
CMS2_k127_2906343_62 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000003425 186.0
CMS2_k127_2906343_63 Belongs to the thioredoxin family K00384,K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000002203 181.0
CMS2_k127_2906343_64 BON domain - - - 0.0000000000000000000000000000000000000000000000003985 183.0
CMS2_k127_2906343_65 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000002126 180.0
CMS2_k127_2906343_66 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000000002856 165.0
CMS2_k127_2906343_67 membrane - - - 0.00000000000000000000000000000000000000000038 169.0
CMS2_k127_2906343_68 protein disulfide oxidoreductase activity - - - 0.000000000000000000000000000000000000001783 156.0
CMS2_k127_2906343_69 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 GO:0003674,GO:0003676,GO:0003677,GO:0003681,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016246,GO:0016441,GO:0016458,GO:0017148,GO:0019222,GO:0022607,GO:0022613,GO:0022618,GO:0030423,GO:0031047,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032268,GO:0032269,GO:0032270,GO:0034248,GO:0034249,GO:0034250,GO:0034622,GO:0034641,GO:0035194,GO:0040029,GO:0040033,GO:0043170,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045974,GO:0045975,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051246,GO:0051247,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000008839 142.0
CMS2_k127_2906343_7 double-strand break repair protein AddB K16899 - 3.6.4.12 5.949e-229 742.0
CMS2_k127_2906343_70 protein conserved in bacteria - - - 0.0000000000000000000000000000000000004161 148.0
CMS2_k127_2906343_71 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000974 146.0
CMS2_k127_2906343_72 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000002938 138.0
CMS2_k127_2906343_73 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000004224 146.0
CMS2_k127_2906343_74 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000001911 136.0
CMS2_k127_2906343_75 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051604,GO:0071704,GO:0097428,GO:1901564,GO:1902494,GO:1990230,GO:1990234 - 0.0000000000000000000000000000000001548 139.0
CMS2_k127_2906343_76 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000007989 133.0
CMS2_k127_2906343_77 Protein of unknown function (DUF1249) K09920 - - 0.000000000000000000000000000000001495 136.0
CMS2_k127_2906343_78 Modulates RecA activity K03565 - - 0.00000000000000000000000000000004969 131.0
CMS2_k127_2906343_79 Protein of unknown function (DUF541) - - - 0.0000000000000000000000000000004738 131.0
CMS2_k127_2906343_8 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.033e-225 708.0
CMS2_k127_2906343_80 Belongs to the HSP15 family K04762 - - 0.000000000000000000000000000002254 124.0
CMS2_k127_2906343_81 Iron-sulphur cluster assembly - - - 0.00000000000000000000000000009122 116.0
CMS2_k127_2906343_82 - - - - 0.00000000000000000000000001799 112.0
CMS2_k127_2906343_83 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000007083 87.0
CMS2_k127_2906343_84 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000162 73.0
CMS2_k127_2906343_9 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 1.22e-216 677.0
CMS2_k127_2907866_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 1.067e-289 902.0
CMS2_k127_2907866_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 1.483e-243 765.0
CMS2_k127_2907866_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 578.0
CMS2_k127_2907866_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 520.0
CMS2_k127_2907866_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 306.0
CMS2_k127_2907866_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000496 217.0
CMS2_k127_2907866_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000000000000000198 162.0
CMS2_k127_2907866_7 Protein of unknown function (DUF2818) - - - 0.000000000000000000000000000000006662 130.0
CMS2_k127_2907866_8 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000002048 122.0
CMS2_k127_2907866_9 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.000000000000000000000002838 104.0
CMS2_k127_3015010_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000084 627.0
CMS2_k127_3015010_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 483.0
CMS2_k127_3015010_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 454.0
CMS2_k127_3015010_3 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 406.0
CMS2_k127_3015010_4 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 358.0
CMS2_k127_3015010_5 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000065 235.0
CMS2_k127_3015010_6 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.00000000000000000000000000000000000000000000000000000000000006778 222.0
CMS2_k127_3015010_7 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.00000000000000000000000000000000000000000000000000000000001269 214.0
CMS2_k127_3015010_8 Integral membrane protein (DUF2244) - - - 0.000000000000000000000000129 112.0
CMS2_k127_3052367_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 4.078e-196 618.0
CMS2_k127_3052367_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 410.0
CMS2_k127_3052367_2 Cold shock K03704 - - 0.0000000000000000000000000002665 115.0
CMS2_k127_3052367_3 - - - - 0.00009159 48.0
CMS2_k127_3052367_4 - - - - 0.0004295 47.0
CMS2_k127_3079629_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 4.413e-201 634.0
CMS2_k127_3079629_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 444.0
CMS2_k127_3079629_10 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000001083 225.0
CMS2_k127_3079629_11 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001191 225.0
CMS2_k127_3079629_12 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000002995 213.0
CMS2_k127_3079629_13 Involved in the binding of tRNA to the ribosomes K02946 GO:0001072,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006355,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0015935,GO:0019219,GO:0019222,GO:0019538,GO:0022626,GO:0022627,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043244,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0140110,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000002484 194.0
CMS2_k127_3079629_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000002212 193.0
CMS2_k127_3079629_15 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000001307 187.0
CMS2_k127_3079629_16 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000002807 168.0
CMS2_k127_3079629_17 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000001436 167.0
CMS2_k127_3079629_18 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000000362 162.0
CMS2_k127_3079629_19 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000222 154.0
CMS2_k127_3079629_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 357.0
CMS2_k127_3079629_20 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.0000000000000000000000000000000000000007431 149.0
CMS2_k127_3079629_21 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000001621 136.0
CMS2_k127_3079629_22 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000004586 127.0
CMS2_k127_3079629_23 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000286 120.0
CMS2_k127_3079629_24 Ribosomal protein L30 K02907 - - 0.000000000000000000008136 92.0
CMS2_k127_3079629_25 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000124 76.0
CMS2_k127_3079629_26 Belongs to the universal ribosomal protein uL29 family K02904 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001657 79.0
CMS2_k127_3079629_27 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000002294 73.0
CMS2_k127_3079629_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 328.0
CMS2_k127_3079629_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 327.0
CMS2_k127_3079629_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 301.0
CMS2_k127_3079629_6 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004161 265.0
CMS2_k127_3079629_7 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005156 261.0
CMS2_k127_3079629_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000005301 249.0
CMS2_k127_3079629_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000001028 242.0
CMS2_k127_3103512_0 COG0138 AICAR transformylase IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 6.585e-246 771.0
CMS2_k127_3103512_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 466.0
CMS2_k127_3103512_2 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000005156 261.0
CMS2_k127_3103512_3 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0003674,GO:0003700,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000244 91.0
CMS2_k127_3103512_4 Protein of unknown function (DUF3426) - - - 0.00000000001094 67.0
CMS2_k127_3160154_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 5.592e-286 886.0
CMS2_k127_3160154_1 Belongs to the PEP-utilizing enzyme family K08483,K08484 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008965,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0016775,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050896,GO:0071704,GO:1901564,GO:1901698 2.7.3.9 9.781e-274 861.0
CMS2_k127_3160154_10 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 498.0
CMS2_k127_3160154_11 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 491.0
CMS2_k127_3160154_12 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 397.0
CMS2_k127_3160154_13 Heat shock protein HtpX K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 394.0
CMS2_k127_3160154_14 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 355.0
CMS2_k127_3160154_15 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008782 325.0
CMS2_k127_3160154_16 subfamily IB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 305.0
CMS2_k127_3160154_17 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 296.0
CMS2_k127_3160154_18 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001876 256.0
CMS2_k127_3160154_19 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001993 257.0
CMS2_k127_3160154_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 9.792e-232 722.0
CMS2_k127_3160154_20 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000000000000000000000000000000000000000000000000000004135 258.0
CMS2_k127_3160154_21 COG3023 Negative regulator of beta-lactamase expression K01447,K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000004009 244.0
CMS2_k127_3160154_22 PFAM ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000001304 246.0
CMS2_k127_3160154_23 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000008154 237.0
CMS2_k127_3160154_24 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000003224 231.0
CMS2_k127_3160154_25 Hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000001123 231.0
CMS2_k127_3160154_26 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001868 228.0
CMS2_k127_3160154_27 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000000000000000000001643 192.0
CMS2_k127_3160154_28 SH3 domain K07184 - - 0.00000000000000000000000000000000000000000000000000002117 196.0
CMS2_k127_3160154_29 FMN_bind - - - 0.0000000000000000000000000000000000000000000000009851 179.0
CMS2_k127_3160154_3 PFAM Type II secretion system protein E K02454 - - 1.379e-220 696.0
CMS2_k127_3160154_30 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000001561 169.0
CMS2_k127_3160154_31 Type II secretion system protein C - - - 0.000000000000000000000000000000239 134.0
CMS2_k127_3160154_32 Subtilase family - - - 0.0000000000000000000000000002817 119.0
CMS2_k127_3160154_33 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000007967 62.0
CMS2_k127_3160154_34 chlorophyll binding - - - 0.000004541 59.0
CMS2_k127_3160154_4 general secretion pathway protein D K02453 - - 3.115e-203 653.0
CMS2_k127_3160154_5 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0019904,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0090304,GO:0097718,GO:0140098,GO:1901360,GO:1901361,GO:1901575 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 563.0
CMS2_k127_3160154_6 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 545.0
CMS2_k127_3160154_7 COG4206 Outer membrane cobalamin receptor protein K16092 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004901 536.0
CMS2_k127_3160154_8 General secretion pathway protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 518.0
CMS2_k127_3160154_9 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 513.0
CMS2_k127_3220495_0 PFAM aminotransferase class-III K01845 - 5.4.3.8 4.268e-201 637.0
CMS2_k127_3220495_1 response regulator K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 564.0
CMS2_k127_3220495_10 general secretion pathway protein K02456 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000000000000000000000000000000000000000000008043 209.0
CMS2_k127_3220495_11 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000000000000000000000000002591 206.0
CMS2_k127_3220495_12 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000000000000000000000000000000000000000004232 197.0
CMS2_k127_3220495_13 Type II secretion system (T2SS), protein J - - - 0.0000000000000000000000000000000000000000000001762 178.0
CMS2_k127_3220495_14 involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.000000000000000000000000000000000000000000038 174.0
CMS2_k127_3220495_15 Response regulator receiver domain K07715 - - 0.0000000000000000000000000000000000000001098 154.0
CMS2_k127_3220495_16 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000006123 160.0
CMS2_k127_3220495_17 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000001095 154.0
CMS2_k127_3220495_18 Domain of unknown function (DUF5063) - - - 0.0000000000000000000000000000000000001221 148.0
CMS2_k127_3220495_19 General secretion pathway protein I K02458 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000006782 114.0
CMS2_k127_3220495_2 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 486.0
CMS2_k127_3220495_20 NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000003108 119.0
CMS2_k127_3220495_21 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000005847 107.0
CMS2_k127_3220495_22 general secretion pathway protein K02457 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.00000000000000000359 92.0
CMS2_k127_3220495_23 Methyltransferase FkbM domain - - - 0.00000000001968 74.0
CMS2_k127_3220495_24 amino acid activation for nonribosomal peptide biosynthetic process K17713 - - 0.000000002723 70.0
CMS2_k127_3220495_3 Acid phosphatase homologues K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 478.0
CMS2_k127_3220495_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 447.0
CMS2_k127_3220495_5 dTDP-glucose 4-6-dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 405.0
CMS2_k127_3220495_6 Glycosyltransferase like family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 363.0
CMS2_k127_3220495_7 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 342.0
CMS2_k127_3220495_8 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002276 256.0
CMS2_k127_3220495_9 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000001926 218.0
CMS2_k127_3589716_0 PFAM Glycoside hydrolase 15-related - - - 0.0 1016.0
CMS2_k127_3589716_1 Belongs to the peptidase S16 family - - - 3.592e-294 923.0
CMS2_k127_3589716_10 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 407.0
CMS2_k127_3589716_11 His Kinase A (phosphoacceptor) domain K10715 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 307.0
CMS2_k127_3589716_12 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002516 276.0
CMS2_k127_3589716_13 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00000000000000000000000000000000000000000000000000000000000000006019 229.0
CMS2_k127_3589716_14 Universal stress protein family - - - 0.000000000000000000000000000000000000007418 156.0
CMS2_k127_3589716_15 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000002666 113.0
CMS2_k127_3589716_16 tryptophan synthase subunit beta - - - 0.00000000000000005941 86.0
CMS2_k127_3589716_17 - - - - 0.00000000000003877 74.0
CMS2_k127_3589716_18 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000006496 60.0
CMS2_k127_3589716_19 DNA polymerase K03502 - - 0.00001872 47.0
CMS2_k127_3589716_2 COG0008 Glutamyl- and glutaminyl-tRNA synthetases K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 2.312e-283 878.0
CMS2_k127_3589716_20 PFAM FecR protein K01406 - 3.4.24.40 0.000154 53.0
CMS2_k127_3589716_21 LuxR family transcriptional regulator K11618 - - 0.0002533 49.0
CMS2_k127_3589716_22 PFAM Sporulation - - - 0.0005654 52.0
CMS2_k127_3589716_3 ABC transporter transmembrane region - - - 5.342e-278 871.0
CMS2_k127_3589716_4 PFAM Endonuclease Exonuclease phosphatase - - - 3.244e-268 848.0
CMS2_k127_3589716_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 2.83e-229 717.0
CMS2_k127_3589716_6 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 511.0
CMS2_k127_3589716_7 TIGRFAM type I secretion membrane fusion protein, HlyD family K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 470.0
CMS2_k127_3589716_8 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005225 467.0
CMS2_k127_3589716_9 Sodium hydrogen antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 430.0
CMS2_k127_3662336_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1545.0
CMS2_k127_3662336_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1201.0
CMS2_k127_3662336_10 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 554.0
CMS2_k127_3662336_11 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 528.0
CMS2_k127_3662336_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 408.0
CMS2_k127_3662336_13 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 419.0
CMS2_k127_3662336_14 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 390.0
CMS2_k127_3662336_15 Protein of unknown function (DUF1538) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 353.0
CMS2_k127_3662336_16 Protein of unknown function (DUF1538) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 345.0
CMS2_k127_3662336_17 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 338.0
CMS2_k127_3662336_18 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 306.0
CMS2_k127_3662336_19 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003441 278.0
CMS2_k127_3662336_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 4.661e-297 927.0
CMS2_k127_3662336_20 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001145 252.0
CMS2_k127_3662336_21 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000000000000000000000000000009014 220.0
CMS2_k127_3662336_22 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000000000000002304 212.0
CMS2_k127_3662336_23 transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000007629 206.0
CMS2_k127_3662336_24 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000006929 195.0
CMS2_k127_3662336_25 helix_turn_helix, mercury resistance K08365,K19591 - - 0.00000000000000000000000000000000000000000000000000000954 192.0
CMS2_k127_3662336_26 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000002616 193.0
CMS2_k127_3662336_27 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000002891 183.0
CMS2_k127_3662336_28 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000002301 170.0
CMS2_k127_3662336_29 Belongs to the P(II) protein family - - - 0.0000000000000000000000000000000000000000181 155.0
CMS2_k127_3662336_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 4.391e-267 831.0
CMS2_k127_3662336_30 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000006859 164.0
CMS2_k127_3662336_31 transcriptional regulator K03892 GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0043170,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0046685,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000008868 134.0
CMS2_k127_3662336_32 Lipid A 3-O-deacylase (PagL) - - - 0.000000000000000000000000000001136 128.0
CMS2_k127_3662336_33 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000006302 121.0
CMS2_k127_3662336_34 Protein of unknown function (DUF2782) - - - 0.00000000000000000000000007909 110.0
CMS2_k127_3662336_35 - - - - 0.00000000000002008 79.0
CMS2_k127_3662336_36 - - - - 0.00000000001091 74.0
CMS2_k127_3662336_37 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K22110 - - 0.000000001082 70.0
CMS2_k127_3662336_39 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000001733 57.0
CMS2_k127_3662336_4 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 3.425e-258 809.0
CMS2_k127_3662336_40 Molydopterin dinucleotide binding domain K07812 - 1.7.2.3 0.000000671 59.0
CMS2_k127_3662336_41 - - - - 0.000009392 54.0
CMS2_k127_3662336_42 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0001907 45.0
CMS2_k127_3662336_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 9.461e-258 798.0
CMS2_k127_3662336_6 ResB-like family K07399 - - 1.617e-206 662.0
CMS2_k127_3662336_7 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 6.423e-202 638.0
CMS2_k127_3662336_8 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 566.0
CMS2_k127_3662336_9 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 557.0
CMS2_k127_3693787_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0 1042.0
CMS2_k127_3693787_1 COG1519 3-deoxy-D-manno-octulosonic-acid transferase K02527 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 465.0
CMS2_k127_3693787_10 Glycosyltransferase family 10 (fucosyltransferase) C-term - - - 0.000000000000000000000000000000009129 137.0
CMS2_k127_3693787_11 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000001539 123.0
CMS2_k127_3693787_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 445.0
CMS2_k127_3693787_3 PFAM glycosyl transferase family 25 K07270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 384.0
CMS2_k127_3693787_4 type I secretion outer membrane protein, TolC K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 355.0
CMS2_k127_3693787_5 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517,K12974 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006082,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0006950,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008951,GO:0009058,GO:0009245,GO:0009247,GO:0009266,GO:0009311,GO:0009312,GO:0009409,GO:0009628,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0036103,GO:0036104,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046467,GO:0046493,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 329.0
CMS2_k127_3693787_6 Glycosyltransferase family 10 (fucosyltransferase) C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 311.0
CMS2_k127_3693787_7 PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000002338 229.0
CMS2_k127_3693787_8 Vibrio cholerae RfbT protein - - - 0.000000000000000000000000000000000000000000001506 176.0
CMS2_k127_3693787_9 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000226 147.0
CMS2_k127_3718145_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 1.764e-197 634.0
CMS2_k127_3718145_1 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 464.0
CMS2_k127_3718145_11 methyltransferase - - - 0.00000000000000003192 87.0
CMS2_k127_3718145_12 methyltransferase - - - 0.000000002076 58.0
CMS2_k127_3718145_13 SnoaL-like domain - - - 0.000005437 53.0
CMS2_k127_3718145_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 385.0
CMS2_k127_3718145_3 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 353.0
CMS2_k127_3718145_4 membrane protein, terc - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 347.0
CMS2_k127_3718145_5 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 319.0
CMS2_k127_3718145_6 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000007675 219.0
CMS2_k127_3718145_7 - - - - 0.00000000000000000000000000000000000000000000000000002246 192.0
CMS2_k127_3718145_8 Cupin domain - - - 0.000000000000000000000000000000000000000000000003466 176.0
CMS2_k127_3718145_9 Protein of unknown function (DUF1304) K08987 - - 0.0000000000000000000000000000000000001908 145.0
CMS2_k127_3768216_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 4.865e-278 884.0
CMS2_k127_3768216_1 Dak2 K00863,K05878 - 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 1.526e-229 723.0
CMS2_k127_3768216_10 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0018130,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0055114,GO:0055129,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 317.0
CMS2_k127_3768216_11 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001066 274.0
CMS2_k127_3768216_12 integral membrane protein K02221 - - 0.000000000000000000000000000000000000000000000000003915 189.0
CMS2_k127_3768216_2 Type II/IV secretion system protein K02669 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 579.0
CMS2_k127_3768216_3 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 570.0
CMS2_k127_3768216_4 PFAM Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006818 556.0
CMS2_k127_3768216_5 PFAM Type II secretion system protein E K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 547.0
CMS2_k127_3768216_6 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 529.0
CMS2_k127_3768216_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 510.0
CMS2_k127_3768216_8 Oxidoreductase FAD-binding domain K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 450.0
CMS2_k127_3768216_9 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 321.0
CMS2_k127_3886862_0 Polysaccharide chain length determinant protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 507.0
CMS2_k127_3886862_1 Polysaccharide biosynthesis protein K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 408.0
CMS2_k127_3886862_2 SMART AAA ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 384.0
CMS2_k127_3886862_3 Capsular exopolysaccharide family K08252,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006118 271.0
CMS2_k127_3886862_4 polysaccharide export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000191 209.0
CMS2_k127_3886862_5 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000003579 166.0
CMS2_k127_3886862_6 - - - - 0.00000000000000006846 87.0
CMS2_k127_4127270_0 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 551.0
CMS2_k127_4127270_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 533.0
CMS2_k127_4127270_10 - - - - 0.0000000000000000000001052 101.0
CMS2_k127_4127270_11 - - - - 0.000000000000000000001565 98.0
CMS2_k127_4127270_13 translation elongation factor activity K02358 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000001051 88.0
CMS2_k127_4127270_14 - - - - 0.00000000001078 66.0
CMS2_k127_4127270_15 - - - - 0.00000007335 54.0
CMS2_k127_4127270_2 PFAM Alcohol dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 410.0
CMS2_k127_4127270_3 PFAM Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006813 342.0
CMS2_k127_4127270_4 PFAM TspO MBR family protein K05770 - - 0.000000000000000000000000000000000000000000000000000000000000000204 225.0
CMS2_k127_4127270_5 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000002999 177.0
CMS2_k127_4127270_6 Excises ethenocytosine and uracil, which can arise by alkylation or deamination of cytosine, respectively, from the corresponding mispairs with guanine in ds-DNA. It is capable of hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of the DNA and the mispaired base. The complementary strand guanine functions in substrate recognition. Required for DNA damage lesion repair in stationary-phase cells K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000002929 167.0
CMS2_k127_4127270_7 Domain of unknown function (DUF4154) - - - 0.000000000000000000000000000002233 126.0
CMS2_k127_4127270_8 - - - - 0.0000000000000000000000000001005 123.0
CMS2_k127_4169325_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1425.0
CMS2_k127_4169325_1 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 3.958e-198 625.0
CMS2_k127_4169325_10 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 383.0
CMS2_k127_4169325_11 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 356.0
CMS2_k127_4169325_12 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 349.0
CMS2_k127_4169325_13 D-isomer specific 2-hydroxyacid dehydrogenase K03778 - 1.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 346.0
CMS2_k127_4169325_14 MazG nucleotide pyrophosphohydrolase domain K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009267,GO:0009394,GO:0009605,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042594,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 292.0
CMS2_k127_4169325_15 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 282.0
CMS2_k127_4169325_16 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009638 273.0
CMS2_k127_4169325_17 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001751 260.0
CMS2_k127_4169325_18 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000005533 237.0
CMS2_k127_4169325_19 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0022607,GO:0030003,GO:0031163,GO:0036455,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0071840,GO:0097428,GO:0098771,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000007971 225.0
CMS2_k127_4169325_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 518.0
CMS2_k127_4169325_20 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000002268 222.0
CMS2_k127_4169325_21 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000004098 230.0
CMS2_k127_4169325_22 - K10716 - - 0.000000000000000000000000000000000000000000000000000000000009577 212.0
CMS2_k127_4169325_23 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000005613 201.0
CMS2_k127_4169325_24 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000003262 200.0
CMS2_k127_4169325_25 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000004205 194.0
CMS2_k127_4169325_26 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000009214 198.0
CMS2_k127_4169325_27 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000003335 184.0
CMS2_k127_4169325_28 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000001795 185.0
CMS2_k127_4169325_29 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000001307 167.0
CMS2_k127_4169325_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 498.0
CMS2_k127_4169325_30 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000002523 160.0
CMS2_k127_4169325_31 Ferric uptake regulator family K09826 - - 0.000000000000000000000000000000000000000509 152.0
CMS2_k127_4169325_32 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000303 144.0
CMS2_k127_4169325_33 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000001164 147.0
CMS2_k127_4169325_34 Peptidyl-prolyl cis-trans K03774 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0061077,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000000000001334 146.0
CMS2_k127_4169325_35 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000001886 143.0
CMS2_k127_4169325_36 DNA polymerase - - - 0.00000000000000000000000000000001559 134.0
CMS2_k127_4169325_37 Host attachment protein - - - 0.0000000000000000000000000001217 120.0
CMS2_k127_4169325_38 Sel1-like repeats. K07126 - - 0.000000000000000000000000000133 119.0
CMS2_k127_4169325_39 Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase K07740 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0010556,GO:0016989,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.00000000000000000000000001317 114.0
CMS2_k127_4169325_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 493.0
CMS2_k127_4169325_40 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000002545 113.0
CMS2_k127_4169325_41 metal cluster binding K06940 - - 0.0000000000000000000000003607 112.0
CMS2_k127_4169325_42 - - - - 0.0000000001335 64.0
CMS2_k127_4169325_43 Putative diguanylate phosphodiesterase - - - 0.00000000127 64.0
CMS2_k127_4169325_44 protein conserved in bacteria K09908 - - 0.000000001382 66.0
CMS2_k127_4169325_47 - - - - 0.0002282 50.0
CMS2_k127_4169325_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 479.0
CMS2_k127_4169325_6 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0042380,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046490,GO:0048037,GO:0051536,GO:0051538,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 470.0
CMS2_k127_4169325_7 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 431.0
CMS2_k127_4169325_8 TIGRFAM TIGR03790 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 399.0
CMS2_k127_4169325_9 Thioredoxin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 380.0
CMS2_k127_4195239_0 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 8.385e-276 861.0
CMS2_k127_4195239_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 3.321e-245 779.0
CMS2_k127_4195239_10 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 377.0
CMS2_k127_4195239_11 signal peptide peptidase SppA K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 353.0
CMS2_k127_4195239_12 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0030203,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0042597,GO:0043170,GO:0044425,GO:0044459,GO:0044464,GO:0061783,GO:0071704,GO:0071944,GO:1901135,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 354.0
CMS2_k127_4195239_13 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 349.0
CMS2_k127_4195239_14 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 338.0
CMS2_k127_4195239_15 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 300.0
CMS2_k127_4195239_16 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 286.0
CMS2_k127_4195239_17 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 286.0
CMS2_k127_4195239_18 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000002167 261.0
CMS2_k127_4195239_19 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000009978 263.0
CMS2_k127_4195239_2 PFAM Carbamoyl-phosphate synthase L chain K01959 - 6.4.1.1 9.382e-237 739.0
CMS2_k127_4195239_20 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000228 240.0
CMS2_k127_4195239_21 Hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000004234 226.0
CMS2_k127_4195239_22 low molecular weight K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000004995 214.0
CMS2_k127_4195239_23 COG0848 Biopolymer transport protein K03559 - - 0.00000000000000000000000000000000000009125 145.0
CMS2_k127_4195239_24 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000592 132.0
CMS2_k127_4195239_25 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000002849 125.0
CMS2_k127_4195239_26 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000005055 104.0
CMS2_k127_4195239_27 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.000000000000000000001964 100.0
CMS2_k127_4195239_28 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000001236 92.0
CMS2_k127_4195239_29 PilZ domain - - - 0.0000004108 57.0
CMS2_k127_4195239_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.389e-196 618.0
CMS2_k127_4195239_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0033818,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 540.0
CMS2_k127_4195239_5 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 536.0
CMS2_k127_4195239_6 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 554.0
CMS2_k127_4195239_7 Anthranilate synthase component I K01657,K01665 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 499.0
CMS2_k127_4195239_8 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 445.0
CMS2_k127_4195239_9 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 388.0
CMS2_k127_4285978_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1262.0
CMS2_k127_4285978_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1107.0
CMS2_k127_4285978_10 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 620.0
CMS2_k127_4285978_11 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 604.0
CMS2_k127_4285978_12 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 593.0
CMS2_k127_4285978_13 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 546.0
CMS2_k127_4285978_14 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 530.0
CMS2_k127_4285978_15 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 526.0
CMS2_k127_4285978_16 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 500.0
CMS2_k127_4285978_17 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 484.0
CMS2_k127_4285978_18 Aminotransferase class I and II K00817 GO:0000105,GO:0003674,GO:0003824,GO:0004400,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 449.0
CMS2_k127_4285978_19 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 447.0
CMS2_k127_4285978_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.624e-279 865.0
CMS2_k127_4285978_20 PFAM PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 437.0
CMS2_k127_4285978_21 Trypsin K04691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 437.0
CMS2_k127_4285978_22 Protein of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 464.0
CMS2_k127_4285978_23 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 421.0
CMS2_k127_4285978_24 oxidoreductase FAD NAD(P)-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 413.0
CMS2_k127_4285978_25 ABC transporter permease K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 391.0
CMS2_k127_4285978_26 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 388.0
CMS2_k127_4285978_27 PFAM ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 385.0
CMS2_k127_4285978_28 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 376.0
CMS2_k127_4285978_29 PFAM Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 361.0
CMS2_k127_4285978_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.754e-240 752.0
CMS2_k127_4285978_30 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 352.0
CMS2_k127_4285978_31 PFAM ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 345.0
CMS2_k127_4285978_32 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 348.0
CMS2_k127_4285978_33 PFAM CBS domain K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008828 344.0
CMS2_k127_4285978_34 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 335.0
CMS2_k127_4285978_35 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 328.0
CMS2_k127_4285978_36 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 320.0
CMS2_k127_4285978_37 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 326.0
CMS2_k127_4285978_38 hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 321.0
CMS2_k127_4285978_39 NGG1p interacting factor 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 318.0
CMS2_k127_4285978_4 modulator of DNA gyrase K03568 - - 3.146e-231 723.0
CMS2_k127_4285978_40 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009337 319.0
CMS2_k127_4285978_41 ThiF family K22132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000393 311.0
CMS2_k127_4285978_42 Cytochrome C1 family K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001687 291.0
CMS2_k127_4285978_43 PFAM Glutathione S-transferase K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004639 274.0
CMS2_k127_4285978_44 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002246 272.0
CMS2_k127_4285978_45 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003943 271.0
CMS2_k127_4285978_46 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000289 262.0
CMS2_k127_4285978_47 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002355 269.0
CMS2_k127_4285978_48 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009995 256.0
CMS2_k127_4285978_49 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000001414 239.0
CMS2_k127_4285978_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 6.803e-222 695.0
CMS2_k127_4285978_50 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000002771 222.0
CMS2_k127_4285978_51 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000009439 218.0
CMS2_k127_4285978_52 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000003833 216.0
CMS2_k127_4285978_53 phosphatase homologous to the C-terminal domain of histone macroH2A1 - GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231 - 0.000000000000000000000000000000000000000000000000000000000001344 213.0
CMS2_k127_4285978_54 Elongation factor P K02356 - - 0.00000000000000000000000000000000000000000000000000000000002964 210.0
CMS2_k127_4285978_55 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000003111 222.0
CMS2_k127_4285978_56 Copper resistance protein D - - - 0.0000000000000000000000000000000000000000000000000000001053 198.0
CMS2_k127_4285978_57 PFAM toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000000000000002221 194.0
CMS2_k127_4285978_58 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000002549 186.0
CMS2_k127_4285978_59 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000004357 182.0
CMS2_k127_4285978_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.159e-220 689.0
CMS2_k127_4285978_60 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000003674 179.0
CMS2_k127_4285978_61 DoxX K15977 - - 0.00000000000000000000000000000000000000000000001538 174.0
CMS2_k127_4285978_62 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.000000000000000000000000000000000000000000008903 168.0
CMS2_k127_4285978_63 Sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000000000001188 154.0
CMS2_k127_4285978_64 Stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000007293 152.0
CMS2_k127_4285978_65 part of a sulfur-relay system K11179 - - 0.00000000000000000000000000000000000000534 148.0
CMS2_k127_4285978_66 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000001507 147.0
CMS2_k127_4285978_67 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000103 147.0
CMS2_k127_4285978_68 Zinc-ribbon containing domain - - - 0.0000000000000000000000000000000000006435 160.0
CMS2_k127_4285978_69 Endonuclease containing a URI domain K07461 - - 0.00000000000000000000000000000000003706 137.0
CMS2_k127_4285978_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 8.817e-206 646.0
CMS2_k127_4285978_70 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000001716 136.0
CMS2_k127_4285978_71 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.000000000000000000000000000000001098 136.0
CMS2_k127_4285978_72 Belongs to the UPF0307 family K09889 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000003612 131.0
CMS2_k127_4285978_73 GIY-YIG catalytic domain K07461 - - 0.00000000000000000000000002823 110.0
CMS2_k127_4285978_74 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.00000000000000000000000008011 109.0
CMS2_k127_4285978_75 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.0000000000000000000000005837 112.0
CMS2_k127_4285978_76 Stress responsive A/B Barrel Domain - - - 0.000000000000000000000005854 107.0
CMS2_k127_4285978_77 - - - - 0.00000000000000000000001732 104.0
CMS2_k127_4285978_78 - - - - 0.0000000000000000003696 91.0
CMS2_k127_4285978_79 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000003722 95.0
CMS2_k127_4285978_8 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 2.365e-205 646.0
CMS2_k127_4285978_80 Belongs to the BolA IbaG family - - - 0.0000000000000000006259 88.0
CMS2_k127_4285978_81 Protein of unknown function (DUF2905) - - - 0.000000000000000001656 90.0
CMS2_k127_4285978_82 Transposase zinc-binding domain - - - 0.000000000000000001767 86.0
CMS2_k127_4285978_83 NTP binding protein (Contains STAS domain) K07122 - - 0.0000000000000001611 83.0
CMS2_k127_4285978_84 Domain of unknown function (DUF3330) - - - 0.000000000004048 67.0
CMS2_k127_4285978_85 - - - - 0.00000000001156 69.0
CMS2_k127_4285978_86 Domain of unknown function (DUF3330) - - - 0.0000000006137 61.0
CMS2_k127_4285978_88 Protein of unknown function (DUF861) K06995 - - 0.0000003975 53.0
CMS2_k127_4285978_89 Ethanolamine utilisation protein EutQ K06995 - - 0.0000005539 52.0
CMS2_k127_4285978_9 TIGRFAM ribonuclease, Rne Rng family K08301 - - 5.239e-205 648.0
CMS2_k127_4285978_90 lipopolysaccharide transmembrane transporter activity K02040,K11719 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0017089,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031975,GO:0033036,GO:0042597,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0046836,GO:0051179,GO:0051234,GO:0071702,GO:0071944,GO:1901264 - 0.0000006615 59.0
CMS2_k127_4285978_91 Protein of unknown function, DUF547 - - - 0.000001425 57.0
CMS2_k127_4285978_92 Tetratricopeptide repeat - - - 0.00005102 52.0
CMS2_k127_4285978_93 Transposase - - - 0.0002224 46.0
CMS2_k127_4426275_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1354.0
CMS2_k127_4426275_1 Extracellular solute-binding protein - - - 2.8e-321 997.0
CMS2_k127_4426275_10 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 576.0
CMS2_k127_4426275_11 Sodium:dicarboxylate symporter family K03309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 532.0
CMS2_k127_4426275_12 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00520 - 1.16.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 507.0
CMS2_k127_4426275_13 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 485.0
CMS2_k127_4426275_14 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 464.0
CMS2_k127_4426275_15 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 443.0
CMS2_k127_4426275_16 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 437.0
CMS2_k127_4426275_17 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 421.0
CMS2_k127_4426275_18 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 415.0
CMS2_k127_4426275_19 PFAM Binding-protein-dependent transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 404.0
CMS2_k127_4426275_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 1.755e-302 937.0
CMS2_k127_4426275_20 Acyltransferase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 390.0
CMS2_k127_4426275_21 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 385.0
CMS2_k127_4426275_22 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 390.0
CMS2_k127_4426275_23 PFAM Fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 385.0
CMS2_k127_4426275_24 Belongs to the agmatine deiminase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 378.0
CMS2_k127_4426275_25 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 373.0
CMS2_k127_4426275_26 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 359.0
CMS2_k127_4426275_27 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 350.0
CMS2_k127_4426275_28 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772,K19696 - 2.4.2.28,2.4.2.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 337.0
CMS2_k127_4426275_29 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 304.0
CMS2_k127_4426275_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.285e-300 928.0
CMS2_k127_4426275_30 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000305 250.0
CMS2_k127_4426275_31 Glycosyl transferase group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004285 245.0
CMS2_k127_4426275_32 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000115 228.0
CMS2_k127_4426275_33 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000000000000000001089 222.0
CMS2_k127_4426275_34 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000001647 225.0
CMS2_k127_4426275_35 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000002437 218.0
CMS2_k127_4426275_36 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000008 186.0
CMS2_k127_4426275_37 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000004382 129.0
CMS2_k127_4426275_38 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000007103 121.0
CMS2_k127_4426275_39 Succinate dehydrogenase hydrophobic membrane anchor K00242 - - 0.00000000000000000000001855 106.0
CMS2_k127_4426275_4 MMPL family K07003 - - 8.449e-291 911.0
CMS2_k127_4426275_40 Flavinator of succinate dehydrogenase K09159 - - 0.00000000000000002673 85.0
CMS2_k127_4426275_41 Putative peptidoglycan binding domain - - - 0.0000000000000007969 80.0
CMS2_k127_4426275_42 - - - - 0.000000000000002608 75.0
CMS2_k127_4426275_43 - - - - 0.000000000000009174 78.0
CMS2_k127_4426275_44 Peptidoglycan-binding protein, CsiV - - - 0.00000000000001104 84.0
CMS2_k127_4426275_45 heat shock protein - - - 0.0000004804 57.0
CMS2_k127_4426275_46 NifU-like domain K19168 - - 0.000002973 55.0
CMS2_k127_4426275_47 Peptidoglycan-binding domain-containing protein - - - 0.00001999 53.0
CMS2_k127_4426275_48 PDZ domain (Also known as DHR or GLGF) K04771 - 3.4.21.107 0.0007843 43.0
CMS2_k127_4426275_5 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032,K13896 - - 6.567e-273 854.0
CMS2_k127_4426275_6 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1e-232 734.0
CMS2_k127_4426275_7 PFAM aminotransferase class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 9.148e-205 642.0
CMS2_k127_4426275_8 DAHP synthetase I family K03856 - 2.5.1.54 8.255e-199 624.0
CMS2_k127_4426275_9 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 580.0
CMS2_k127_4468437_0 Belongs to the DEAD box helicase family K05591 GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 557.0
CMS2_k127_4468437_1 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 391.0
CMS2_k127_4468437_10 to the N-terminal domain of Lon protease K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000001205 132.0
CMS2_k127_4468437_11 Tryptophan-rich protein (DUF2389) - - - 0.000000000000000000000000000003395 121.0
CMS2_k127_4468437_12 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000004295 123.0
CMS2_k127_4468437_13 Alternative locus ID K15383 - - 0.0000000000000000000000219 102.0
CMS2_k127_4468437_14 - - - - 0.000000000000000002783 93.0
CMS2_k127_4468437_15 Expressed protein K14621 - 3.1.1.4,3.1.1.5 0.00000001885 66.0
CMS2_k127_4468437_16 amine dehydrogenase activity - - - 0.0000023 59.0
CMS2_k127_4468437_17 Putative transposase - - - 0.0001689 46.0
CMS2_k127_4468437_2 transporter component K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 374.0
CMS2_k127_4468437_3 PFAM Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 321.0
CMS2_k127_4468437_4 nuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002346 258.0
CMS2_k127_4468437_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001531 260.0
CMS2_k127_4468437_6 Protein of unknown function (DUF3050) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001433 257.0
CMS2_k127_4468437_7 SMART Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000002732 241.0
CMS2_k127_4468437_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000101 218.0
CMS2_k127_4468437_9 YCII-related domain - - - 0.00000000000000000000000000000009551 126.0
CMS2_k127_4780025_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2464.0
CMS2_k127_4780025_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 2.239e-284 891.0
CMS2_k127_4780025_10 Zn-dependent protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 475.0
CMS2_k127_4780025_11 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 400.0
CMS2_k127_4780025_12 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 364.0
CMS2_k127_4780025_13 PFAM Fructosamine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 341.0
CMS2_k127_4780025_14 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 309.0
CMS2_k127_4780025_15 PFAM YicC-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 293.0
CMS2_k127_4780025_16 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001551 259.0
CMS2_k127_4780025_17 Pilus assembly protein PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005046 254.0
CMS2_k127_4780025_18 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000002013 213.0
CMS2_k127_4780025_19 PFAM Fimbrial assembly K02663 - - 0.0000000000000000000000000000000000000000000000000007399 189.0
CMS2_k127_4780025_2 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 3.781e-269 850.0
CMS2_k127_4780025_20 nuclease - - - 0.000000000000000000000000000000000000000000002881 177.0
CMS2_k127_4780025_21 pilus assembly protein PilP K02665 - - 0.00000000000000000000000000000000000000000003637 166.0
CMS2_k127_4780025_22 Sel1-like repeats. - - - 0.000000000000000000000000000000000000001507 151.0
CMS2_k127_4780025_23 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000004123 115.0
CMS2_k127_4780025_24 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000121 110.0
CMS2_k127_4780025_25 - - - - 0.000000000000000004197 86.0
CMS2_k127_4780025_26 Cysteine-rich CPXCG - - - 0.0000000000000000116 84.0
CMS2_k127_4780025_27 Protein of unknown function (DUF3135) - - - 0.0000000000000002212 84.0
CMS2_k127_4780025_28 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.00000000002257 67.0
CMS2_k127_4780025_3 Pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 9.673e-246 767.0
CMS2_k127_4780025_30 cheY-homologous receiver domain - - - 0.00003616 50.0
CMS2_k127_4780025_31 rho-dependent transcription termination K19000 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00004342 49.0
CMS2_k127_4780025_4 type IV pilus secretin PilQ K02666 - - 1.213e-220 704.0
CMS2_k127_4780025_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 547.0
CMS2_k127_4780025_6 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 518.0
CMS2_k127_4780025_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 489.0
CMS2_k127_4780025_8 Pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 475.0
CMS2_k127_4780025_9 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 472.0
CMS2_k127_489153_0 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 5.002e-298 916.0
CMS2_k127_489153_1 Sulfate transporter antisigma-factor antagonist STAS - - - 2.417e-229 729.0
CMS2_k127_489153_10 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 303.0
CMS2_k127_489153_11 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007816 265.0
CMS2_k127_489153_12 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004037 244.0
CMS2_k127_489153_13 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000002194 214.0
CMS2_k127_489153_14 carboxysome shell protein - - - 0.00000000000000000000000000000000000000000000000000001024 190.0
CMS2_k127_489153_15 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000004328 186.0
CMS2_k127_489153_16 BMC - - - 0.0000000000000000000000000000000000000000000000002697 177.0
CMS2_k127_489153_17 Thioredoxin domain - - - 0.000000000000000000000000000000000000000000000002074 181.0
CMS2_k127_489153_18 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000002119 182.0
CMS2_k127_489153_19 Iron-storage protein, whose ferroxidase center binds Fe(2 ) ions, oxidizes them by dioxygen to Fe(3 ), and participates in the subsequent Fe(3 ) oxide mineral core formation within the central cavity of the protein complex K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000004981 175.0
CMS2_k127_489153_2 Carboxysome shell peptide mid-region - - - 3.241e-225 720.0
CMS2_k127_489153_20 PFAM Ethanolamine utilization protein EutN carboxysome structural protein Ccml - - - 0.000000000000000000000000000000000000001045 150.0
CMS2_k127_489153_21 WHG domain - - - 0.0000000000000000000000000000000000005484 147.0
CMS2_k127_489153_22 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000000000002313 131.0
CMS2_k127_489153_23 - - - - 0.000000000000000000000000000000001797 132.0
CMS2_k127_489153_24 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000000000000003685 130.0
CMS2_k127_489153_25 Pterin 4 alpha carbinolamine dehydratase - - - 0.00000000000000000000000000002542 119.0
CMS2_k127_489153_26 - - - - 0.0000000000000000000007656 100.0
CMS2_k127_489153_28 - - - - 0.00000001658 59.0
CMS2_k127_489153_29 Sporulation related domain - - - 0.00000001788 62.0
CMS2_k127_489153_3 TIGRFAM carboxysome shell carbonic anhydrase - - - 3.885e-216 681.0
CMS2_k127_489153_30 COG NOG14600 non supervised orthologous group - - - 0.00002496 49.0
CMS2_k127_489153_4 Sulfate transporter K03321 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015106,GO:0015318,GO:0015701,GO:0015711,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656 - 4.001e-197 630.0
CMS2_k127_489153_5 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07713 GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 533.0
CMS2_k127_489153_6 LysR family K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009367 470.0
CMS2_k127_489153_7 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 372.0
CMS2_k127_489153_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 342.0
CMS2_k127_489153_9 BMC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 331.0
CMS2_k127_4929305_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 3.829e-275 863.0
CMS2_k127_4929305_1 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000000000001106 220.0
CMS2_k127_5114654_0 ABC transporter - - - 3.25e-304 940.0
CMS2_k127_5114654_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.933e-226 705.0
CMS2_k127_5114654_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 482.0
CMS2_k127_5114654_3 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 442.0
CMS2_k127_5114654_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 439.0
CMS2_k127_5114654_5 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 296.0
CMS2_k127_5114654_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000001981 229.0
CMS2_k127_5114654_7 Rhodanese Homology Domain - - - 0.000000000001954 72.0
CMS2_k127_5114654_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.0000004204 61.0
CMS2_k127_5127831_0 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 356.0
CMS2_k127_5127831_1 Phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 353.0
CMS2_k127_5127831_2 Belongs to the HesB IscA family K15724 - - 0.000000000000000000000000000000000001003 142.0
CMS2_k127_5127831_3 Bacterial Fe(2+) trafficking - - - 0.000000000000000000000000000000003085 131.0
CMS2_k127_5127831_4 PFAM Uncharacterised protein family (UPF0093) K08973 - - 0.000000000000000000002673 94.0
CMS2_k127_5215227_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 444.0
CMS2_k127_5215227_1 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.00000000000000000000000000000003369 130.0
CMS2_k127_5215227_2 succinate dehydrogenase K00242 - - 0.000000000000000001025 95.0
CMS2_k127_5337293_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.868e-293 916.0
CMS2_k127_5337293_1 Ion channel K10716 - - 1.488e-209 666.0
CMS2_k127_5337293_10 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 419.0
CMS2_k127_5337293_11 Domain of unknown function (DUF3524) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 411.0
CMS2_k127_5337293_12 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 404.0
CMS2_k127_5337293_13 Metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 405.0
CMS2_k127_5337293_14 metal ion transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 364.0
CMS2_k127_5337293_15 Acyl-transferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 314.0
CMS2_k127_5337293_16 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 299.0
CMS2_k127_5337293_17 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 300.0
CMS2_k127_5337293_18 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000855 271.0
CMS2_k127_5337293_19 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000395 263.0
CMS2_k127_5337293_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 1.12e-208 674.0
CMS2_k127_5337293_20 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001123 245.0
CMS2_k127_5337293_21 PFAM AhpC TSA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001048 237.0
CMS2_k127_5337293_22 Protein of unknown function, DUF481 - - - 0.00000000000000000000000000000000000000000000000000000000000001148 228.0
CMS2_k127_5337293_23 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000002961 196.0
CMS2_k127_5337293_24 - - - - 0.000000000000000000000000000000000000000000000000000006651 193.0
CMS2_k127_5337293_25 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000002208 171.0
CMS2_k127_5337293_26 - - - - 0.000000000000000000000000000000000000000000006022 164.0
CMS2_k127_5337293_27 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000007894 174.0
CMS2_k127_5337293_28 Haem-degrading - - - 0.0000000000000000000000000000000000000000002306 164.0
CMS2_k127_5337293_29 - - - - 0.00000000000000000000000000000000000000001488 157.0
CMS2_k127_5337293_3 POT family K03305 - - 7.16e-201 634.0
CMS2_k127_5337293_30 transcriptional regulator - - - 0.0000000000000000000000000000000000000000222 154.0
CMS2_k127_5337293_31 Histidine phosphatase superfamily (branch 1) K08296 - - 0.0000000000000000000000000000000000000004897 154.0
CMS2_k127_5337293_32 - - - - 0.0000000000000000000000000000000000000005272 153.0
CMS2_k127_5337293_33 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000000000000000000000002564 152.0
CMS2_k127_5337293_34 - - - - 0.00000000000000000000000000000000001148 140.0
CMS2_k127_5337293_35 CDP-archaeol synthase K19664 - 2.7.7.67 0.0000000000000000000000000000000004064 136.0
CMS2_k127_5337293_36 - - - - 0.0000000000000000000000000000000004264 138.0
CMS2_k127_5337293_37 - - - - 0.00000000000000000000000000000002331 130.0
CMS2_k127_5337293_38 Glutaredoxin - - - 0.000000000000000000000000008631 111.0
CMS2_k127_5337293_39 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000008308 108.0
CMS2_k127_5337293_4 glutamate--cysteine ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 582.0
CMS2_k127_5337293_40 - - - - 0.0000000000000000000000001516 108.0
CMS2_k127_5337293_42 protein structure with unknown function - - - 0.000000000000000000001912 97.0
CMS2_k127_5337293_43 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.000000000000000000095 93.0
CMS2_k127_5337293_45 Rhs family - - - 0.0000000009838 68.0
CMS2_k127_5337293_47 - - - - 0.000000002143 63.0
CMS2_k127_5337293_48 Protein of unknown function (DUF3301) - - - 0.00000007387 59.0
CMS2_k127_5337293_49 Belongs to the GSP D family K02666 - - 0.0000002051 57.0
CMS2_k127_5337293_5 PFAM Sodium sulphate symporter K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 540.0
CMS2_k127_5337293_53 Bacterial flagellin C-terminal helical region K02406 - - 0.0001727 45.0
CMS2_k127_5337293_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 506.0
CMS2_k127_5337293_7 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 490.0
CMS2_k127_5337293_8 PFAM Succinylglutamate desuccinylase Aspartoacylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 435.0
CMS2_k127_5337293_9 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 432.0
CMS2_k127_5361562_0 Ferrous iron transport protein B K04759 - - 1.046e-233 737.0
CMS2_k127_5361562_1 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 586.0
CMS2_k127_5361562_2 FeoA K04758 - - 0.0000000006684 64.0
CMS2_k127_5366090_0 MMPL family K18138 - - 0.0 1615.0
CMS2_k127_5366090_1 Sodium:solute symporter family K14393 - - 4.161e-298 923.0
CMS2_k127_5366090_10 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000006836 198.0
CMS2_k127_5366090_11 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000001739 173.0
CMS2_k127_5366090_12 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000001351 166.0
CMS2_k127_5366090_13 Membrane - - - 0.000000000000000000000000000000000000000003106 170.0
CMS2_k127_5366090_14 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000002155 140.0
CMS2_k127_5366090_15 Membrane - - - 0.000000000000000000000000000000267 128.0
CMS2_k127_5366090_16 Cytochrome c - - - 0.0000000000000000000009342 97.0
CMS2_k127_5366090_17 Conserved repeat domain - - - 0.000000000003277 80.0
CMS2_k127_5366090_19 amine dehydrogenase activity - - - 0.000007065 59.0
CMS2_k127_5366090_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0042802,GO:0043170,GO:0043846,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050790,GO:0061695,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007732 543.0
CMS2_k127_5366090_3 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 497.0
CMS2_k127_5366090_4 Transcriptional regulator K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 446.0
CMS2_k127_5366090_5 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 402.0
CMS2_k127_5366090_6 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 348.0
CMS2_k127_5366090_7 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 294.0
CMS2_k127_5366090_8 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 288.0
CMS2_k127_5366090_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007449 283.0
CMS2_k127_5391876_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1815.0
CMS2_k127_5391876_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1222.0
CMS2_k127_5391876_10 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.654e-197 623.0
CMS2_k127_5391876_11 AAA ATPase, central domain protein K07478 - - 9.453e-196 618.0
CMS2_k127_5391876_12 Starch synthase catalytic domain K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 584.0
CMS2_k127_5391876_13 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 525.0
CMS2_k127_5391876_14 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 503.0
CMS2_k127_5391876_15 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 500.0
CMS2_k127_5391876_16 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 460.0
CMS2_k127_5391876_17 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 450.0
CMS2_k127_5391876_18 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 444.0
CMS2_k127_5391876_19 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17229 - 1.8.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 447.0
CMS2_k127_5391876_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1162.0
CMS2_k127_5391876_20 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 434.0
CMS2_k127_5391876_21 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 427.0
CMS2_k127_5391876_22 FIST N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 413.0
CMS2_k127_5391876_23 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 405.0
CMS2_k127_5391876_24 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 406.0
CMS2_k127_5391876_25 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 379.0
CMS2_k127_5391876_26 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 327.0
CMS2_k127_5391876_27 Belongs to the BI1 family K19416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 315.0
CMS2_k127_5391876_28 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 294.0
CMS2_k127_5391876_29 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001673 273.0
CMS2_k127_5391876_3 C-terminal, D2-small domain, of ClpB protein K03694 - - 0.0 1048.0
CMS2_k127_5391876_30 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000001816 253.0
CMS2_k127_5391876_31 RNA pseudouridylate synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005224 241.0
CMS2_k127_5391876_32 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 240.0
CMS2_k127_5391876_33 - - - - 0.0000000000000000000000000000000000000000000000000000000000001055 218.0
CMS2_k127_5391876_34 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000304 183.0
CMS2_k127_5391876_35 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000002839 183.0
CMS2_k127_5391876_37 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000003165 173.0
CMS2_k127_5391876_38 - - - - 0.000000000000000000000000000000000000000000009152 167.0
CMS2_k127_5391876_39 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000001318 158.0
CMS2_k127_5391876_4 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 6.29e-316 981.0
CMS2_k127_5391876_40 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000000000000003959 163.0
CMS2_k127_5391876_41 High frequency lysogenization protein HflD homolog K07153 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009898,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:0098562 - 0.00000000000000000000000000000000000000001527 160.0
CMS2_k127_5391876_42 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.000000000000000000000000000000000000007006 148.0
CMS2_k127_5391876_43 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000003427 140.0
CMS2_k127_5391876_44 SseB protein N-terminal domain - - - 0.00000000000000000000000000000000004891 138.0
CMS2_k127_5391876_45 CAAX protease self-immunity K07052 - - 0.00000000000000000000000004663 113.0
CMS2_k127_5391876_46 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000001192 107.0
CMS2_k127_5391876_47 - - - - 0.0000000000002668 72.0
CMS2_k127_5391876_48 PFAM Cytochrome C K17230 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000761 73.0
CMS2_k127_5391876_5 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 7.429e-288 903.0
CMS2_k127_5391876_51 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0001134 46.0
CMS2_k127_5391876_6 Belongs to the GPI family K01810 - 5.3.1.9 7.286e-259 807.0
CMS2_k127_5391876_7 Glycosyl hydrolase family 57 - - - 3.348e-221 699.0
CMS2_k127_5391876_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.491e-214 674.0
CMS2_k127_5391876_9 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 2.985e-207 652.0
CMS2_k127_5508759_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1479.0
CMS2_k127_5508759_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1181.0
CMS2_k127_5508759_10 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 5.032e-259 819.0
CMS2_k127_5508759_100 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000001366 146.0
CMS2_k127_5508759_101 protein conserved in archaea - - - 0.00000000000000000000000000000007343 130.0
CMS2_k127_5508759_102 Belongs to the skp family K06142 - - 0.00000000000000000000000000000009247 131.0
CMS2_k127_5508759_103 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000001594 108.0
CMS2_k127_5508759_104 Type II transport protein GspH K08084 - - 0.000000000000000000000003213 109.0
CMS2_k127_5508759_105 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000005414 102.0
CMS2_k127_5508759_106 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000008838 103.0
CMS2_k127_5508759_107 Belongs to the ompA family K20276 - - 0.000000000000000000000182 109.0
CMS2_k127_5508759_108 Tetratricopeptide repeat - - - 0.00000000000000000002275 99.0
CMS2_k127_5508759_109 Protein of unknown function (DUF2892) - - - 0.00000000000000000006258 92.0
CMS2_k127_5508759_11 PFAM Na Picotransporter K03324 - - 5.264e-231 730.0
CMS2_k127_5508759_110 domain protein K03006,K07004,K13735 - 2.7.7.6 0.00000000000000008775 92.0
CMS2_k127_5508759_111 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.000000000000002753 82.0
CMS2_k127_5508759_112 Domain of unknown function (DUF4082) - - - 0.000000000001044 79.0
CMS2_k127_5508759_113 - - - - 0.000000000008361 75.0
CMS2_k127_5508759_114 Cytochrome c assembly protein - - - 0.00000000003825 64.0
CMS2_k127_5508759_115 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000000644 61.0
CMS2_k127_5508759_116 Na H antiporter - - - 0.000000005053 57.0
CMS2_k127_5508759_118 hydrolase K01048 - 3.1.1.5 0.0000003716 51.0
CMS2_k127_5508759_119 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.000001031 59.0
CMS2_k127_5508759_12 HELICc2 K03722 GO:0003674,GO:0003824,GO:0004386,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0090304,GO:1901360 3.6.4.12 2.076e-229 728.0
CMS2_k127_5508759_120 Alkaline phosphatase - - - 0.000003531 54.0
CMS2_k127_5508759_122 Tetratricopeptide repeat - - - 0.00004824 51.0
CMS2_k127_5508759_123 amine dehydrogenase activity - - - 0.00006147 54.0
CMS2_k127_5508759_124 Citrate transporter - - - 0.0001808 48.0
CMS2_k127_5508759_13 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 8.61e-225 705.0
CMS2_k127_5508759_14 PFAM Aminotransferase class I and II K14261 - - 1.083e-224 700.0
CMS2_k127_5508759_15 single-stranded-DNA-specific exonuclease RecJ K07462 - - 1.336e-216 686.0
CMS2_k127_5508759_16 homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 1.613e-214 674.0
CMS2_k127_5508759_17 Polyphosphate kinase 2 (PPK2) - - - 2.363e-204 648.0
CMS2_k127_5508759_18 protein conserved in bacteria K09800 GO:0002790,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0097347 - 1.672e-196 659.0
CMS2_k127_5508759_19 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 3.587e-196 617.0
CMS2_k127_5508759_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1038.0
CMS2_k127_5508759_20 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.538e-195 617.0
CMS2_k127_5508759_21 COG0436 Aspartate tyrosine aromatic aminotransferase K00812,K12252 - 2.6.1.1,2.6.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 596.0
CMS2_k127_5508759_22 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 568.0
CMS2_k127_5508759_23 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 563.0
CMS2_k127_5508759_24 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 550.0
CMS2_k127_5508759_25 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007711 527.0
CMS2_k127_5508759_26 Belongs to the RimK family K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 516.0
CMS2_k127_5508759_27 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 512.0
CMS2_k127_5508759_28 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 500.0
CMS2_k127_5508759_29 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 491.0
CMS2_k127_5508759_3 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1035.0
CMS2_k127_5508759_30 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 496.0
CMS2_k127_5508759_31 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 489.0
CMS2_k127_5508759_32 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 488.0
CMS2_k127_5508759_33 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009883 481.0
CMS2_k127_5508759_34 Lysin motif K08307 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 490.0
CMS2_k127_5508759_35 Surface antigen variable number K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 491.0
CMS2_k127_5508759_36 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009952 473.0
CMS2_k127_5508759_37 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 460.0
CMS2_k127_5508759_38 phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 447.0
CMS2_k127_5508759_39 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 436.0
CMS2_k127_5508759_4 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 3.263e-293 925.0
CMS2_k127_5508759_40 Succinylglutamate desuccinylase aspartoacylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 433.0
CMS2_k127_5508759_41 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 421.0
CMS2_k127_5508759_42 Catalyzes the formation of phosphoenolpyruvate from pyruvate K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 427.0
CMS2_k127_5508759_43 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 408.0
CMS2_k127_5508759_44 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 405.0
CMS2_k127_5508759_45 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 406.0
CMS2_k127_5508759_46 COG0568 DNA-directed RNA polymerase, sigma subunit K03087 GO:0000988,GO:0000990,GO:0001000,GO:0001121,GO:0001123,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 399.0
CMS2_k127_5508759_47 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 412.0
CMS2_k127_5508759_48 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 402.0
CMS2_k127_5508759_49 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008194,GO:0008289,GO:0008610,GO:0008654,GO:0008915,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0019637,GO:0019897,GO:0019898,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 396.0
CMS2_k127_5508759_5 Cytochrome c-type biogenesis protein K02198 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564 - 7.79e-293 914.0
CMS2_k127_5508759_50 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 387.0
CMS2_k127_5508759_51 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 389.0
CMS2_k127_5508759_52 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 381.0
CMS2_k127_5508759_53 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 380.0
CMS2_k127_5508759_54 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 GO:0002097,GO:0002101,GO:0002136,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0032267,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 387.0
CMS2_k127_5508759_55 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 369.0
CMS2_k127_5508759_56 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 365.0
CMS2_k127_5508759_57 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 356.0
CMS2_k127_5508759_58 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 356.0
CMS2_k127_5508759_59 negative regulation of phosphate transmembrane transport K01104,K02039,K03741 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 1.20.4.1,3.1.3.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 328.0
CMS2_k127_5508759_6 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.325e-276 859.0
CMS2_k127_5508759_60 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 317.0
CMS2_k127_5508759_61 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 313.0
CMS2_k127_5508759_62 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342,K14159 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7,3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 312.0
CMS2_k127_5508759_63 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 299.0
CMS2_k127_5508759_64 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009804 296.0
CMS2_k127_5508759_65 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004626 283.0
CMS2_k127_5508759_66 PFAM Mg2 transporter protein, CorA family protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007442 282.0
CMS2_k127_5508759_67 TIGRFAM Cytochrome c-type biogenesis protein CcmI K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003263 276.0
CMS2_k127_5508759_68 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050518,GO:0070567,GO:0071704,GO:1901576 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000004742 261.0
CMS2_k127_5508759_69 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 258.0
CMS2_k127_5508759_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 4.167e-276 868.0
CMS2_k127_5508759_70 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000009966 253.0
CMS2_k127_5508759_71 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015232,GO:0015886,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019897,GO:0019898,GO:0022857,GO:0031224,GO:0031234,GO:0032991,GO:0042623,GO:0043190,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098533,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:1901678,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000001034 253.0
CMS2_k127_5508759_72 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0030091,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000001763 253.0
CMS2_k127_5508759_73 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000004457 253.0
CMS2_k127_5508759_74 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001038 249.0
CMS2_k127_5508759_75 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000004976 240.0
CMS2_k127_5508759_76 Uncharacterized protein family, UPF0114 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000175 242.0
CMS2_k127_5508759_77 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000001516 230.0
CMS2_k127_5508759_78 Sel1-like repeats. - - - 0.000000000000000000000000000000000000000000000000000000000000000004375 232.0
CMS2_k127_5508759_79 COG0526 Thiol-disulfide isomerase and thioredoxins K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000006019 229.0
CMS2_k127_5508759_8 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 1.442e-275 868.0
CMS2_k127_5508759_80 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000002966 224.0
CMS2_k127_5508759_81 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015886,GO:0016020,GO:0016043,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0019538,GO:0020037,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051181,GO:0051234,GO:0065003,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0097159,GO:0098552,GO:0098567,GO:1901363,GO:1901564,GO:1901678 - 0.0000000000000000000000000000000000000000000000000000000000175 210.0
CMS2_k127_5508759_82 PFAM regulatory protein, MerR - - - 0.00000000000000000000000000000000000000000000000000000000001977 207.0
CMS2_k127_5508759_83 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000000000000000003183 213.0
CMS2_k127_5508759_84 COG0739 Membrane proteins related to metalloendopeptidases K06194 - - 0.0000000000000000000000000000000000000000000000000000000001585 214.0
CMS2_k127_5508759_85 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000005378 210.0
CMS2_k127_5508759_86 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000001158 205.0
CMS2_k127_5508759_87 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000002281 209.0
CMS2_k127_5508759_88 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000004239 206.0
CMS2_k127_5508759_89 ATP cone domain K05715 - - 0.000000000000000000000000000000000000000000000000000001371 206.0
CMS2_k127_5508759_9 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.236e-260 810.0
CMS2_k127_5508759_90 Putative ATP-dependant zinc protease - - - 0.000000000000000000000000000000000000000000000000000001571 195.0
CMS2_k127_5508759_91 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000798 196.0
CMS2_k127_5508759_92 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000001377 184.0
CMS2_k127_5508759_93 Conserved Protein - - - 0.0000000000000000000000000000000000000000000000001556 185.0
CMS2_k127_5508759_94 lactoylglutathione lyase activity K08234 - - 0.0000000000000000000000000000000000000000000000452 172.0
CMS2_k127_5508759_95 PFAM methyltransferase - - - 0.000000000000000000000000000000000000000000002903 174.0
CMS2_k127_5508759_96 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000002387 156.0
CMS2_k127_5508759_97 Smr protein MutS2 - - - 0.00000000000000000000000000000000000000003092 159.0
CMS2_k127_5508759_98 subunit of a heme lyase K02200 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017004,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071840,GO:0071944,GO:0098552,GO:0098567 - 0.0000000000000000000000000000000000000002905 154.0
CMS2_k127_5508759_99 Belongs to the ArsC family K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.0000000000000000000000000000000000000006062 153.0
CMS2_k127_5516446_0 Ammonium Transporter K03320 - - 1.446e-201 635.0
CMS2_k127_5516446_1 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 493.0
CMS2_k127_5516446_2 PFAM conserved K02069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 347.0
CMS2_k127_5516446_3 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04752 - - 0.00000000000000000000000000000000000000000000000000000002003 198.0
CMS2_k127_5516446_4 pfam abc - - - 0.0000000000000000000000000000000000000000000000000007536 191.0
CMS2_k127_5516446_5 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000003661 132.0
CMS2_k127_5521277_0 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 566.0
CMS2_k127_5521277_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 447.0
CMS2_k127_5521277_10 Protein of unknown function (DUF502) - - - 0.00000000000000000000952 99.0
CMS2_k127_5521277_11 Protein of unknown function (DUF2909) - - - 0.0000000000000009582 79.0
CMS2_k127_5521277_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 379.0
CMS2_k127_5521277_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 383.0
CMS2_k127_5521277_4 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 359.0
CMS2_k127_5521277_5 Insulinase (Peptidase family M16) K00960,K07263 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 336.0
CMS2_k127_5521277_6 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 316.0
CMS2_k127_5521277_7 Part of the ABC transporter FtsEX involved in cellular division K09811 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0009274,GO:0009276,GO:0009987,GO:0016020,GO:0016021,GO:0030312,GO:0030313,GO:0031224,GO:0031975,GO:0032153,GO:0044425,GO:0044464,GO:0051301,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009559 290.0
CMS2_k127_5521277_8 SURF1-like protein - - - 0.000000000000000000000000000000000000000000000006776 181.0
CMS2_k127_5521277_9 signal sequence binding - - - 0.000000000000000000000000000001109 129.0
CMS2_k127_5527799_0 FAD binding domain K00394 - 1.8.99.2 0.0 1225.0
CMS2_k127_5527799_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1221.0
CMS2_k127_5527799_10 AAA-like domain K06915 - - 1.394e-202 645.0
CMS2_k127_5527799_11 PFAM phosphate transporter K03306 - - 4.357e-198 624.0
CMS2_k127_5527799_12 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 2.314e-195 627.0
CMS2_k127_5527799_13 Hydrogenase formation hypA family K04654 GO:0003674,GO:0005488,GO:0005506,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0019538,GO:0036211,GO:0042165,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046914,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0051604,GO:0070025,GO:0071704,GO:1901564 - 1.495e-194 611.0
CMS2_k127_5527799_14 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 614.0
CMS2_k127_5527799_15 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 596.0
CMS2_k127_5527799_16 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 586.0
CMS2_k127_5527799_17 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 512.0
CMS2_k127_5527799_18 PFAM AsmA family K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 506.0
CMS2_k127_5527799_19 AIR synthase related protein, N-terminal domain K04655 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0018193,GO:0018198,GO:0018249,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046892,GO:0051604,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 480.0
CMS2_k127_5527799_2 Alpha amylase catalytic K05341,K05343 - 2.4.1.4,3.2.1.1,5.4.99.16 0.0 1067.0
CMS2_k127_5527799_20 P COG0025 NhaP-type Na H and K H antiporters K11747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 467.0
CMS2_k127_5527799_21 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 462.0
CMS2_k127_5527799_22 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 448.0
CMS2_k127_5527799_23 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 453.0
CMS2_k127_5527799_24 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 447.0
CMS2_k127_5527799_25 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 437.0
CMS2_k127_5527799_26 COG1194 A G-specific DNA glycosylase K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 439.0
CMS2_k127_5527799_27 PFAM Lytic K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 428.0
CMS2_k127_5527799_28 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 399.0
CMS2_k127_5527799_29 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 391.0
CMS2_k127_5527799_3 HAD-superfamily hydrolase, subfamily IIB K00696 - 2.4.1.14 1.002e-317 987.0
CMS2_k127_5527799_30 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 382.0
CMS2_k127_5527799_31 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 377.0
CMS2_k127_5527799_32 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 375.0
CMS2_k127_5527799_33 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 368.0
CMS2_k127_5527799_34 NAD-dependent epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 364.0
CMS2_k127_5527799_35 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 357.0
CMS2_k127_5527799_36 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 309.0
CMS2_k127_5527799_37 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008885 305.0
CMS2_k127_5527799_38 HPP family K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 308.0
CMS2_k127_5527799_39 PfkB domain protein K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 299.0
CMS2_k127_5527799_4 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 9.787e-297 931.0
CMS2_k127_5527799_40 TIGRFAM HAD-superfamily hydrolase, subfamily IIB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 298.0
CMS2_k127_5527799_41 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 283.0
CMS2_k127_5527799_42 COG1573 Uracil-DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000373 277.0
CMS2_k127_5527799_43 COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002673 271.0
CMS2_k127_5527799_44 Protein of unknown function (DUF429) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003927 271.0
CMS2_k127_5527799_45 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006695 265.0
CMS2_k127_5527799_46 Transcriptional regulator K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000848 258.0
CMS2_k127_5527799_47 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000001127 250.0
CMS2_k127_5527799_48 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000008963 240.0
CMS2_k127_5527799_49 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 GO:0003674,GO:0003824,GO:0008119,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008757,GO:0010035,GO:0010038,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0046690,GO:0050896 2.1.1.67 0.000000000000000000000000000000000000000000000000000000000002914 216.0
CMS2_k127_5527799_5 HypF finger - - - 1.8e-273 862.0
CMS2_k127_5527799_50 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000001412 203.0
CMS2_k127_5527799_51 - - - - 0.0000000000000000000000000000000000000000000000000000002606 200.0
CMS2_k127_5527799_52 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000001961 195.0
CMS2_k127_5527799_53 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000000003982 186.0
CMS2_k127_5527799_54 - - - - 0.0000000000000000000000000000000000000000000000000005874 190.0
CMS2_k127_5527799_55 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000001662 184.0
CMS2_k127_5527799_56 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000005336 187.0
CMS2_k127_5527799_57 - - - - 0.00000000000000000000000000000000000000000000000007413 185.0
CMS2_k127_5527799_58 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000001244 164.0
CMS2_k127_5527799_59 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000003005 158.0
CMS2_k127_5527799_6 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 9.847e-267 834.0
CMS2_k127_5527799_60 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000002569 143.0
CMS2_k127_5527799_61 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000000000000002704 140.0
CMS2_k127_5527799_62 MlaC protein - - - 0.0000000000000000000000000000000001024 141.0
CMS2_k127_5527799_63 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000003137 138.0
CMS2_k127_5527799_64 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000000001328 124.0
CMS2_k127_5527799_65 Cytochrome c - - - 0.0000000000000000000000000000006882 125.0
CMS2_k127_5527799_66 - - - - 0.00000000000000000000000000004198 124.0
CMS2_k127_5527799_67 - - - - 0.0000000000000000000000000001967 121.0
CMS2_k127_5527799_68 methyltransferase activity - - - 0.000000000000000000000000000208 123.0
CMS2_k127_5527799_69 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000001407 118.0
CMS2_k127_5527799_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 1.44e-251 789.0
CMS2_k127_5527799_70 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000008706 110.0
CMS2_k127_5527799_71 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000000000000007377 106.0
CMS2_k127_5527799_72 - - - - 0.0000000000000000000000009662 106.0
CMS2_k127_5527799_73 protein conserved in bacteria K01790 GO:0008150,GO:0009987,GO:0042710,GO:0044010,GO:0044764,GO:0051704 5.1.3.13 0.000000000000000000000002114 106.0
CMS2_k127_5527799_74 - K09004 - - 0.000000000000000000001441 102.0
CMS2_k127_5527799_76 Sulphur globule protein - - - 0.0000000000000000001501 93.0
CMS2_k127_5527799_77 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000002851 94.0
CMS2_k127_5527799_78 Phospholipase_D-nuclease N-terminal - - - 0.0000000000000002012 87.0
CMS2_k127_5527799_79 Thiamine biosynthesis protein ThiS K03154 - - 0.000000000000001629 81.0
CMS2_k127_5527799_8 AMP-binding enzyme K01897 - 6.2.1.3 4.095e-240 756.0
CMS2_k127_5527799_80 - - - - 0.00000000000322 69.0
CMS2_k127_5527799_81 PCO_ADO K10712 - 1.13.11.19 0.00000000005876 71.0
CMS2_k127_5527799_82 4Fe-4S single cluster domain - - - 0.0000000003219 67.0
CMS2_k127_5527799_83 YeeE YedE family protein K07112 - - 0.00000005492 65.0
CMS2_k127_5527799_84 - - - - 0.00000136 50.0
CMS2_k127_5527799_9 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 2.672e-210 671.0
CMS2_k127_570754_0 Monomeric isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1053.0
CMS2_k127_570754_1 Sulfate permease family - - - 3.765e-309 963.0
CMS2_k127_570754_10 Lipase maturation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 422.0
CMS2_k127_570754_11 polyphosphate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 396.0
CMS2_k127_570754_12 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 405.0
CMS2_k127_570754_13 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 364.0
CMS2_k127_570754_14 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 377.0
CMS2_k127_570754_15 PLD-like domain K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 364.0
CMS2_k127_570754_16 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 353.0
CMS2_k127_570754_17 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 311.0
CMS2_k127_570754_18 Domain of unknown function (DUF4202) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 306.0
CMS2_k127_570754_19 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 303.0
CMS2_k127_570754_2 pfam abc - - - 9.017e-275 852.0
CMS2_k127_570754_20 ribonuclease BN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 299.0
CMS2_k127_570754_21 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 291.0
CMS2_k127_570754_22 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001411 275.0
CMS2_k127_570754_23 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004187 272.0
CMS2_k127_570754_24 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001244 267.0
CMS2_k127_570754_25 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000002744 206.0
CMS2_k127_570754_26 protein serine/threonine phosphatase activity K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000002557 211.0
CMS2_k127_570754_27 PFAM SEC-C motif K09858 - - 0.00000000000000000000000000000000000000000000000000001215 196.0
CMS2_k127_570754_28 - - - - 0.0000000000000000000000000000000000000000000000002697 184.0
CMS2_k127_570754_29 Disulfide bond formation protein DsbB - - - 0.000000000000000000000000000000000000000000002586 169.0
CMS2_k127_570754_3 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 2.044e-225 709.0
CMS2_k127_570754_30 transglycosylase - - - 0.00000000000000000000000000000000000000001258 172.0
CMS2_k127_570754_31 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000004507 160.0
CMS2_k127_570754_32 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000001407 151.0
CMS2_k127_570754_33 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - 0.00000000000000000000000000001589 132.0
CMS2_k127_570754_34 OmpA family - - - 0.000000000000000000000001145 111.0
CMS2_k127_570754_35 - - - - 0.000000000000000000000002314 104.0
CMS2_k127_570754_36 GCN5-related N-acetyl-transferase K06975 - - 0.0000000000000000000000132 102.0
CMS2_k127_570754_37 CHAD - - - 0.000000000000000000000593 107.0
CMS2_k127_570754_38 YceI-like domain - - - 0.000000000000000000005859 101.0
CMS2_k127_570754_39 - - - - 0.00000000000000000005147 95.0
CMS2_k127_570754_4 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0042254,GO:0042255,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 9.045e-204 645.0
CMS2_k127_570754_40 - - - - 0.0000000000000000003293 92.0
CMS2_k127_570754_41 - - - - 0.00000000000003656 73.0
CMS2_k127_570754_42 - - - - 0.00000000000006797 76.0
CMS2_k127_570754_43 - - - - 0.000000000001158 76.0
CMS2_k127_570754_44 phosphoprotein phosphatase activity - - - 0.00000000001565 73.0
CMS2_k127_570754_46 Metallo-beta-lactamase superfamily - - - 0.00000009651 59.0
CMS2_k127_570754_49 Sulphur globule protein - - - 0.000297 51.0
CMS2_k127_570754_5 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.941e-202 636.0
CMS2_k127_570754_6 Belongs to the UPF0061 (SELO) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 583.0
CMS2_k127_570754_7 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 500.0
CMS2_k127_570754_8 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 489.0
CMS2_k127_570754_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 424.0
CMS2_k127_5716877_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.938e-249 790.0
CMS2_k127_575937_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1763.0
CMS2_k127_575937_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1020.0
CMS2_k127_575937_10 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 428.0
CMS2_k127_575937_11 AI-2E family transporter K03548 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 420.0
CMS2_k127_575937_12 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 415.0
CMS2_k127_575937_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 382.0
CMS2_k127_575937_14 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 366.0
CMS2_k127_575937_15 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 372.0
CMS2_k127_575937_16 Histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 376.0
CMS2_k127_575937_17 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 346.0
CMS2_k127_575937_18 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 326.0
CMS2_k127_575937_19 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 322.0
CMS2_k127_575937_2 6-phosphogluconolactonase activity - - - 2.913e-289 923.0
CMS2_k127_575937_20 NlpB/DapX lipoprotein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 316.0
CMS2_k127_575937_21 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 306.0
CMS2_k127_575937_22 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 303.0
CMS2_k127_575937_23 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 300.0
CMS2_k127_575937_24 Putative DNA-binding domain K09929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 300.0
CMS2_k127_575937_25 DoxX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003817 284.0
CMS2_k127_575937_26 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000302 273.0
CMS2_k127_575937_27 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000852 276.0
CMS2_k127_575937_28 - K00673 - 2.3.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000008906 249.0
CMS2_k127_575937_29 response regulator K15012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001136 246.0
CMS2_k127_575937_3 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 601.0
CMS2_k127_575937_30 ACT domain K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000002167 231.0
CMS2_k127_575937_31 Peroxiredoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000008327 236.0
CMS2_k127_575937_32 Belongs to the DnaA family. HdA subfamily K10763 - - 0.00000000000000000000000000000000000000000000000000000000000000004215 229.0
CMS2_k127_575937_33 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000000001333 229.0
CMS2_k127_575937_34 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000003104 213.0
CMS2_k127_575937_35 protein conserved in bacteria K09938 - - 0.0000000000000000000000000000000000000000000000000000000004547 214.0
CMS2_k127_575937_36 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000002811 198.0
CMS2_k127_575937_37 PFAM CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000005984 190.0
CMS2_k127_575937_38 luxR family - - - 0.000000000000000000000000000000000000000001084 166.0
CMS2_k127_575937_39 Belongs to the P-Pant transferase superfamily K06133 - - 0.000000000000000000000000000000000000004427 155.0
CMS2_k127_575937_4 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 592.0
CMS2_k127_575937_40 - - - - 0.0000000000000000000000000000000000003395 151.0
CMS2_k127_575937_41 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000002492 139.0
CMS2_k127_575937_42 - - - - 0.00000000000000000000000006847 111.0
CMS2_k127_575937_43 - - - - 0.000000000000000746 85.0
CMS2_k127_575937_44 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000002097 75.0
CMS2_k127_575937_45 spectrin binding - - - 0.0000000000002116 79.0
CMS2_k127_575937_46 Protein of unknown function (DUF3617) - - - 0.000000000003184 72.0
CMS2_k127_575937_47 Thrombospondin 1b K04659,K16857 GO:0000187,GO:0000302,GO:0001501,GO:0001525,GO:0001568,GO:0001666,GO:0001786,GO:0001817,GO:0001818,GO:0001819,GO:0001932,GO:0001934,GO:0001936,GO:0001937,GO:0001944,GO:0001952,GO:0001953,GO:0001968,GO:0002040,GO:0002376,GO:0002544,GO:0002576,GO:0002577,GO:0002578,GO:0002580,GO:0002581,GO:0002604,GO:0002605,GO:0002682,GO:0002683,GO:0002684,GO:0002685,GO:0002687,GO:0002688,GO:0002690,GO:0002694,GO:0002696,GO:0003007,GO:0003151,GO:0003197,GO:0003416,GO:0003417,GO:0003674,GO:0005102,GO:0005178,GO:0005488,GO:0005509,GO:0005515,GO:0005518,GO:0005539,GO:0005543,GO:0005575,GO:0005576,GO:0005577,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005886,GO:0006417,GO:0006464,GO:0006807,GO:0006810,GO:0006887,GO:0006897,GO:0006909,GO:0006911,GO:0006928,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0006979,GO:0007049,GO:0007050,GO:0007155,GO:0007162,GO:0007275,GO:0007507,GO:0007610,GO:0008150,GO:0008152,GO:0008201,GO:0008284,GO:0008285,GO:0008289,GO:0009266,GO:0009408,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009887,GO:0009888,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009897,GO:0009966,GO:0009967,GO:0009968,GO:0009986,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010324,GO:0010466,GO:0010468,GO:0010556,GO:0010557,GO:0010562,GO:0010594,GO:0010595,GO:0010596,GO:0010604,GO:0010605,GO:0010608,GO:0010628,GO:0010629,GO:0010632,GO:0010633,GO:0010634,GO:0010646,GO:0010647,GO:0010648,GO:0010746,GO:0010748,GO:0010749,GO:0010751,GO:0010752,GO:0010754,GO:0010755,GO:0010757,GO:0010758,GO:0010759,GO:0010762,GO:0010763,GO:0010810,GO:0010811,GO:0010812,GO:0010941,GO:0010942,GO:0010951,GO:0010955,GO:0012505,GO:0014070,GO:0016020,GO:0016043,GO:0016192,GO:0016477,GO:0016525,GO:0016528,GO:0016529,GO:0017015,GO:0017134,GO:0018149,GO:0019220,GO:0019222,GO:0019538,GO:0019838,GO:0019955,GO:0022402,GO:0022603,GO:0022610,GO:0023051,GO:0023056,GO:0023057,GO:0030141,GO:0030155,GO:0030162,GO:0030169,GO:0030193,GO:0030194,GO:0030198,GO:0030334,GO:0030335,GO:0030336,GO:0030511,GO:0031012,GO:0031091,GO:0031093,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031399,GO:0031401,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032026,GO:0032101,GO:0032102,GO:0032103,GO:0032147,GO:0032268,GO:0032269,GO:0032270,GO:0032368,GO:0032369,GO:0032501,GO:0032502,GO:0032570,GO:0032655,GO:0032680,GO:0032695,GO:0032760,GO:0032879,GO:0032890,GO:0032891,GO:0032908,GO:0032914,GO:0032940,GO:0032991,GO:0033554,GO:0033555,GO:0033674,GO:0033993,GO:0034248,GO:0034250,GO:0034284,GO:0034599,GO:0034605,GO:0034614,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0034774,GO:0034976,GO:0035239,GO:0035265,GO:0035295,GO:0035690,GO:0036211,GO:0036293,GO:0040007,GO:0040011,GO:0040012,GO:0040013,GO:0040017,GO:0040036,GO:0040037,GO:0042035,GO:0042108,GO:0042127,GO:0042221,GO:0042325,GO:0042327,GO:0042493,GO:0042534,GO:0042535,GO:0042802,GO:0042981,GO:0043030,GO:0043032,GO:0043062,GO:0043065,GO:0043066,GO:0043067,GO:0043068,GO:0043069,GO:0043085,GO:0043086,GO:0043154,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043236,GO:0043269,GO:0043271,GO:0043277,GO:0043281,GO:0043394,GO:0043405,GO:0043406,GO:0043408,GO:0043410,GO:0043412,GO:0043535,GO:0043536,GO:0043537,GO:0043549,GO:0043652,GO:0044070,GO:0044087,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0044877,GO:0045055,GO:0045595,GO:0045637,GO:0045652,GO:0045727,GO:0045765,GO:0045766,GO:0045785,GO:0045786,GO:0045859,GO:0045860,GO:0045861,GO:0045937,GO:0046872,GO:0046903,GO:0048265,GO:0048266,GO:0048513,GO:0048514,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048545,GO:0048583,GO:0048584,GO:0048585,GO:0048589,GO:0048646,GO:0048660,GO:0048661,GO:0048705,GO:0048731,GO:0048856,GO:0048870,GO:0050431,GO:0050678,GO:0050680,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050818,GO:0050820,GO:0050839,GO:0050840,GO:0050865,GO:0050867,GO:0050878,GO:0050896,GO:0050920,GO:0050921,GO:0050922,GO:0051049,GO:0051051,GO:0051093,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051179,GO:0051216,GO:0051234,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051270,GO:0051271,GO:0051272,GO:0051336,GO:0051338,GO:0051346,GO:0051347,GO:0051592,GO:0051674,GO:0051716,GO:0051726,GO:0051893,GO:0051895,GO:0051896,GO:0051897,GO:0051917,GO:0051918,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060485,GO:0060548,GO:0061024,GO:0061041,GO:0061448,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070051,GO:0070052,GO:0070482,GO:0070613,GO:0070887,GO:0071241,GO:0071622,GO:0071634,GO:0071636,GO:0071675,GO:0071704,GO:0071731,GO:0071732,GO:0071813,GO:0071814,GO:0071840,GO:0071900,GO:0071902,GO:0071944,GO:0072341,GO:0072358,GO:0072359,GO:0080090,GO:0080134,GO:0090049,GO:0090051,GO:0090092,GO:0090100,GO:0090109,GO:0090287,GO:0090288,GO:0090303,GO:0097366,GO:0097367,GO:0097708,GO:0098552,GO:0098657,GO:0098868,GO:0099024,GO:0099503,GO:1900046,GO:1900048,GO:1901342,GO:1901343,GO:1901564,GO:1901654,GO:1901681,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901888,GO:1901889,GO:1902041,GO:1902043,GO:1902170,GO:1902531,GO:1902532,GO:1902533,GO:1903034,GO:1903036,GO:1903317,GO:1903318,GO:1903391,GO:1903392,GO:1903555,GO:1903557,GO:1903587,GO:1903588,GO:1903670,GO:1903671,GO:1903706,GO:1903792,GO:1903844,GO:1903846,GO:1903959,GO:1903960,GO:1904018,GO:1904035,GO:1904037,GO:1905521,GO:1905523,GO:1905952,GO:1905953,GO:2000026,GO:2000112,GO:2000116,GO:2000117,GO:2000145,GO:2000146,GO:2000147,GO:2000181,GO:2000191,GO:2000192,GO:2000351,GO:2000353,GO:2000377,GO:2000379,GO:2001026,GO:2001027,GO:2001233,GO:2001234,GO:2001235,GO:2001236,GO:2001237,GO:2001238 - 0.0000009048 63.0
CMS2_k127_575937_48 Belongs to the SlyX family K03745 - - 0.0001368 47.0
CMS2_k127_575937_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 559.0
CMS2_k127_575937_6 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 544.0
CMS2_k127_575937_7 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 509.0
CMS2_k127_575937_8 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 448.0
CMS2_k127_575937_9 protein conserved in bacteria K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 425.0
CMS2_k127_5826125_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 3.027e-207 650.0
CMS2_k127_5826125_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 407.0
CMS2_k127_5826125_2 Putative transposase - - - 0.0000000000000000000000000000001188 128.0
CMS2_k127_5826125_3 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005979,GO:0006109,GO:0006139,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010675,GO:0010677,GO:0010906,GO:0010962,GO:0016070,GO:0016071,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032881,GO:0032885,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043255,GO:0043467,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045719,GO:0045912,GO:0045947,GO:0046483,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0062012,GO:0065007,GO:0070873,GO:0070874,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.000000000000000000000006912 102.0
CMS2_k127_5826125_4 - - - - 0.0000005258 52.0
CMS2_k127_5826125_5 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000007924 55.0
CMS2_k127_5910300_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 4.163e-300 931.0
CMS2_k127_5910300_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.88e-196 622.0
CMS2_k127_5910300_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 464.0
CMS2_k127_5910300_3 PFAM HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 323.0
CMS2_k127_5910300_4 Exodeoxyribonuclease IX - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 298.0
CMS2_k127_5910300_5 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000007021 162.0
CMS2_k127_6198643_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1270.0
CMS2_k127_6198643_1 Protein of unknown function, DUF255 K06888 - - 9.161e-266 836.0
CMS2_k127_6198643_10 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007149 430.0
CMS2_k127_6198643_11 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 412.0
CMS2_k127_6198643_12 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0036094,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046184,GO:0046483,GO:0046872,GO:0046914,GO:0048037,GO:0050570,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000573 408.0
CMS2_k127_6198643_13 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 396.0
CMS2_k127_6198643_14 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 381.0
CMS2_k127_6198643_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 387.0
CMS2_k127_6198643_16 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K18800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 362.0
CMS2_k127_6198643_17 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 350.0
CMS2_k127_6198643_18 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 330.0
CMS2_k127_6198643_19 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 306.0
CMS2_k127_6198643_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 1.4.4.2 3.021e-250 778.0
CMS2_k127_6198643_20 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006246 265.0
CMS2_k127_6198643_21 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006961 269.0
CMS2_k127_6198643_22 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000007767 252.0
CMS2_k127_6198643_23 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000002137 244.0
CMS2_k127_6198643_24 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000003402 244.0
CMS2_k127_6198643_25 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000000262 210.0
CMS2_k127_6198643_26 PFAM ApaG domain protein K06195 - - 0.000000000000000000000000000000000000000000000000000001431 196.0
CMS2_k127_6198643_27 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000006278 187.0
CMS2_k127_6198643_28 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000003815 184.0
CMS2_k127_6198643_29 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000003001 186.0
CMS2_k127_6198643_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 2.596e-213 673.0
CMS2_k127_6198643_30 WD domain, G-beta repeat - - - 0.00000000000000000000000000000000000000001831 165.0
CMS2_k127_6198643_31 Gram-negative porin - - - 0.0000000000000000000000000000000007843 143.0
CMS2_k127_6198643_32 Predicted membrane protein (DUF2238) K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000001938 131.0
CMS2_k127_6198643_33 Belongs to the UPF0149 family K09895 - - 0.000000000000000000000000000001337 127.0
CMS2_k127_6198643_34 Psort location OuterMembrane, score K18133 - - 0.000000000000000000000000000009604 131.0
CMS2_k127_6198643_35 - - - - 0.0000000000000000000001944 102.0
CMS2_k127_6198643_36 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000921,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007010,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0030428,GO:0031106,GO:0032153,GO:0032185,GO:0032505,GO:0032506,GO:0034622,GO:0042802,GO:0043093,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051301,GO:0061640,GO:0065003,GO:0070925,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - 0.000000000000000000003403 96.0
CMS2_k127_6198643_37 TIGRFAM TIGR02449 family protein K09892 - - 0.0000000000002026 73.0
CMS2_k127_6198643_4 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 7.871e-206 649.0
CMS2_k127_6198643_5 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 1.826e-195 618.0
CMS2_k127_6198643_6 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 558.0
CMS2_k127_6198643_7 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008914 502.0
CMS2_k127_6198643_8 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 474.0
CMS2_k127_6198643_9 PFAM pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 475.0
CMS2_k127_6327971_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1198.0
CMS2_k127_6327971_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 7.575e-284 885.0
CMS2_k127_6327971_10 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 1.185e-205 648.0
CMS2_k127_6327971_11 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 2.315e-197 626.0
CMS2_k127_6327971_12 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 605.0
CMS2_k127_6327971_13 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 579.0
CMS2_k127_6327971_14 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 571.0
CMS2_k127_6327971_15 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 546.0
CMS2_k127_6327971_16 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 537.0
CMS2_k127_6327971_17 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 532.0
CMS2_k127_6327971_18 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 515.0
CMS2_k127_6327971_19 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 444.0
CMS2_k127_6327971_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.847e-281 869.0
CMS2_k127_6327971_20 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 429.0
CMS2_k127_6327971_21 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 421.0
CMS2_k127_6327971_22 ATP synthase A chain K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 422.0
CMS2_k127_6327971_23 nitric oxide reductase activity K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 413.0
CMS2_k127_6327971_24 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 408.0
CMS2_k127_6327971_25 Diaminopimelate epimerase K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 377.0
CMS2_k127_6327971_26 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 379.0
CMS2_k127_6327971_27 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 371.0
CMS2_k127_6327971_28 Signal transduction histidine kinase, nitrogen specific K07708 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 363.0
CMS2_k127_6327971_29 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 350.0
CMS2_k127_6327971_3 glutamine synthetase K01915 - 6.3.1.2 4.908e-259 803.0
CMS2_k127_6327971_30 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 344.0
CMS2_k127_6327971_31 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 340.0
CMS2_k127_6327971_32 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 340.0
CMS2_k127_6327971_33 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 335.0
CMS2_k127_6327971_34 signal transduction protein with a C-terminal ATPase domain K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 312.0
CMS2_k127_6327971_35 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016787,GO:0017076,GO:0019538,GO:0019904,GO:0022607,GO:0030163,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0051603,GO:0065003,GO:0070003,GO:0070011,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 282.0
CMS2_k127_6327971_36 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002853 281.0
CMS2_k127_6327971_37 Response regulator of the LytR AlgR family K08083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009557 278.0
CMS2_k127_6327971_38 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001689 267.0
CMS2_k127_6327971_39 Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004715 259.0
CMS2_k127_6327971_4 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 8.503e-237 753.0
CMS2_k127_6327971_40 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000004002 248.0
CMS2_k127_6327971_41 COG4942 Membrane-bound metallopeptidase - GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000001144 249.0
CMS2_k127_6327971_42 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 GO:0001510,GO:0002128,GO:0002130,GO:0002131,GO:0002132,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016427,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052665,GO:0052666,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000002286 225.0
CMS2_k127_6327971_43 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000003493 211.0
CMS2_k127_6327971_44 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.000000000000000000000000000000000000000000000000000000004432 201.0
CMS2_k127_6327971_45 protein conserved in bacteria K09798 - - 0.000000000000000000000000000000000000000000000000000000007119 207.0
CMS2_k127_6327971_46 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000006109 196.0
CMS2_k127_6327971_47 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000001787 199.0
CMS2_k127_6327971_48 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000007484 177.0
CMS2_k127_6327971_49 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000008666 179.0
CMS2_k127_6327971_5 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 GO:0003674,GO:0003824,GO:0004619,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0030145,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046537,GO:0046700,GO:0046872,GO:0046914,GO:0046939,GO:0050896,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 5.4.2.12 3.015e-232 729.0
CMS2_k127_6327971_50 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000001472 183.0
CMS2_k127_6327971_51 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000001559 175.0
CMS2_k127_6327971_52 - - - - 0.0000000000000000000000000000000000000000000001018 174.0
CMS2_k127_6327971_53 surface antigen - - - 0.0000000000000000000000000000000000000000000005179 173.0
CMS2_k127_6327971_54 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000006076 171.0
CMS2_k127_6327971_55 17 kDa outer membrane surface antigen - - - 0.000000000000000000000000000000000000000000004814 168.0
CMS2_k127_6327971_56 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000001471 167.0
CMS2_k127_6327971_57 protein conserved in bacteria K03690 - - 0.00000000000000000000000000000000000000000001888 171.0
CMS2_k127_6327971_58 Phosphoribosyl-ATP pyrophosphohydrolase - - - 0.0000000000000000000000000000000000000000002247 164.0
CMS2_k127_6327971_59 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000002064 135.0
CMS2_k127_6327971_6 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.304e-231 728.0
CMS2_k127_6327971_60 amine dehydrogenase activity - - - 0.000000000000000000000000000000001182 146.0
CMS2_k127_6327971_61 PFAM Rhodanese-like - - - 0.000000000000000000000000000000002639 133.0
CMS2_k127_6327971_62 transcriptional regulator K18831 GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000001126 129.0
CMS2_k127_6327971_63 transcriptional regulator - - - 0.00000000000000000000000000001127 126.0
CMS2_k127_6327971_64 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000003024 126.0
CMS2_k127_6327971_65 Thioredoxin-like domain - - - 0.00000000000000000000000003499 116.0
CMS2_k127_6327971_66 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000005632 105.0
CMS2_k127_6327971_67 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000002026 106.0
CMS2_k127_6327971_68 Belongs to the sulfur carrier protein TusA family - - - 0.0000000000000000000002286 98.0
CMS2_k127_6327971_69 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000208 95.0
CMS2_k127_6327971_7 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 1.223e-223 706.0
CMS2_k127_6327971_70 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001583 73.0
CMS2_k127_6327971_71 Domain of unknown function (DUF4124) - - - 0.000000002381 66.0
CMS2_k127_6327971_72 ATP synthase I chain K02116 - - 0.00000002622 60.0
CMS2_k127_6327971_73 general secretion pathway protein K02452 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.0000293 53.0
CMS2_k127_6327971_8 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 9.378e-213 668.0
CMS2_k127_6327971_9 Chromate transporter K07240 - - 5.157e-210 662.0
CMS2_k127_6368756_0 acyl-CoA dehydrogenase K06445 - - 4.233e-275 869.0
CMS2_k127_6368756_1 PFAM 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 2.302e-245 775.0
CMS2_k127_6368756_10 Domain of unknown function (DUF5062) - - - 0.000000000000000000000000000001591 122.0
CMS2_k127_6368756_11 Alanine-zipper, major outer membrane lipoprotein K06078 - - 0.000000000622 63.0
CMS2_k127_6368756_2 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 6.377e-234 739.0
CMS2_k127_6368756_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 570.0
CMS2_k127_6368756_4 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 457.0
CMS2_k127_6368756_5 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 341.0
CMS2_k127_6368756_6 PilZ domain K02676 - - 0.000000000000000000000000000000000000000000000000000001381 193.0
CMS2_k127_6368756_7 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000004247 192.0
CMS2_k127_6368756_8 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000009471 168.0
CMS2_k127_6368756_9 Thioesterase superfamily protein K10806 - - 0.0000000000000000000000000000000000000000002492 161.0
CMS2_k127_6451541_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 622.0
CMS2_k127_6451541_1 Mitochondrial fission ELM1 K07276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 304.0
CMS2_k127_6451541_2 Zinc-finger domain - - - 0.00000000000000000000001592 101.0
CMS2_k127_652802_0 PFAM YkuD domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 397.0
CMS2_k127_652802_1 pfam abc K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 386.0
CMS2_k127_652802_10 Evidence 4 Homologs of previously reported genes of K09700 - - 0.00000000000000000000000000000000000000000000000001246 180.0
CMS2_k127_652802_11 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000006059 180.0
CMS2_k127_652802_12 PepSY-associated TM region - - - 0.00000000000000000000000000000000000000000002768 167.0
CMS2_k127_652802_13 protein conserved in bacteria K09906 - - 0.0000000000000000000000000000000000000008112 153.0
CMS2_k127_652802_14 pfam nlp p60 K13695 - - 0.0000000000000000000000000000000000002872 146.0
CMS2_k127_652802_15 Protein of unknown function (DUF1499) - - - 0.00000000000000000000000000000003513 130.0
CMS2_k127_652802_19 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00007088 48.0
CMS2_k127_652802_2 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 322.0
CMS2_k127_652802_3 Lysophospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 302.0
CMS2_k127_652802_4 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008372 276.0
CMS2_k127_652802_5 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000000002139 231.0
CMS2_k127_652802_6 TIGRFAM Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000001044 224.0
CMS2_k127_652802_7 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007262 225.0
CMS2_k127_652802_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000002885 219.0
CMS2_k127_652802_9 17 kDa outer membrane surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000001938 216.0
CMS2_k127_6535076_0 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 457.0
CMS2_k127_6535076_1 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 403.0
CMS2_k127_6535076_2 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009318 317.0
CMS2_k127_6535076_3 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 296.0
CMS2_k127_6535076_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008955,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0030203,GO:0034645,GO:0042546,GO:0043164,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000007807 245.0
CMS2_k127_6535076_5 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000009573 136.0
CMS2_k127_6535076_6 peptidase K01414 - 3.4.24.70 0.0000000000000000000000009654 103.0
CMS2_k127_669731_0 Salmonella virulence plasmid 65kDa B protein - - - 2.213e-249 844.0
CMS2_k127_669731_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 317.0
CMS2_k127_669731_2 - - - - 0.00007794 54.0
CMS2_k127_6810201_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 4.901e-309 953.0
CMS2_k127_6810201_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.361e-303 940.0
CMS2_k127_6810201_10 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K11747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 498.0
CMS2_k127_6810201_11 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 476.0
CMS2_k127_6810201_12 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 465.0
CMS2_k127_6810201_13 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 413.0
CMS2_k127_6810201_14 3'-5' exonuclease K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 377.0
CMS2_k127_6810201_15 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 376.0
CMS2_k127_6810201_16 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 345.0
CMS2_k127_6810201_17 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 340.0
CMS2_k127_6810201_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 307.0
CMS2_k127_6810201_19 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 299.0
CMS2_k127_6810201_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.196e-269 834.0
CMS2_k127_6810201_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002988 280.0
CMS2_k127_6810201_21 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002863 269.0
CMS2_k127_6810201_22 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000004703 262.0
CMS2_k127_6810201_23 Pfam Enoyl-CoA hydratase isomerase K13816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001403 263.0
CMS2_k127_6810201_24 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000202 241.0
CMS2_k127_6810201_25 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003085 231.0
CMS2_k127_6810201_26 Protein of unknown function (DUF1318) - - - 0.0000000000000000000000000000000000000000000000000000000000000002114 226.0
CMS2_k127_6810201_27 MucB/RseB C-terminal domain K03598 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152 - 0.000000000000000000000000000000000000000000000000000000000002048 221.0
CMS2_k127_6810201_28 Histidine kinase K10715 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000004425 218.0
CMS2_k127_6810201_29 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000003424 203.0
CMS2_k127_6810201_3 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 2.808e-266 827.0
CMS2_k127_6810201_30 Belongs to the UPF0260 family K09160 - - 0.0000000000000000000000000000000000000000000000000000006069 197.0
CMS2_k127_6810201_31 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000522 179.0
CMS2_k127_6810201_32 arsenate reductase K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000005097 162.0
CMS2_k127_6810201_33 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000013 158.0
CMS2_k127_6810201_34 PFAM macrophage migration inhibitory factor - - - 0.0000000000000000000000000000000000000004456 152.0
CMS2_k127_6810201_35 response to oxidative stress K03803 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000165 146.0
CMS2_k127_6810201_36 - - - - 0.0000000000000000000000000000000000003362 150.0
CMS2_k127_6810201_37 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000001297 140.0
CMS2_k127_6810201_38 acylphosphatase K01512 - 3.6.1.7 0.000000000000000000000000001353 113.0
CMS2_k127_6810201_39 membrane - - - 0.00000000000000000000003384 102.0
CMS2_k127_6810201_4 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 7.806e-260 811.0
CMS2_k127_6810201_40 cell adhesion - - - 0.0000000000000000003047 92.0
CMS2_k127_6810201_41 PFAM glutaredoxin 2 - - - 0.000000000000000003866 88.0
CMS2_k127_6810201_42 PFAM Anti sigma-E protein RseA K03597 - - 0.000000000000002086 83.0
CMS2_k127_6810201_43 COG0642 Signal transduction histidine kinase K07678 GO:0000155,GO:0000160,GO:0000302,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009636,GO:0009927,GO:0009987,GO:0010033,GO:0010035,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042221,GO:0042493,GO:0042542,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046677,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901700 2.7.13.3 0.00000003936 61.0
CMS2_k127_6810201_44 Domain of unknown function (DUF4124) - - - 0.0007604 49.0
CMS2_k127_6810201_5 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.268e-249 781.0
CMS2_k127_6810201_6 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 4.446e-234 736.0
CMS2_k127_6810201_7 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 571.0
CMS2_k127_6810201_8 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 559.0
CMS2_k127_6810201_9 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 511.0
CMS2_k127_6957130_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1644.0
CMS2_k127_6957130_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1071.0
CMS2_k127_6957130_10 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 590.0
CMS2_k127_6957130_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 519.0
CMS2_k127_6957130_12 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 523.0
CMS2_k127_6957130_13 Belongs to the peptidase M48B family K03799 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044425,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 426.0
CMS2_k127_6957130_14 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 411.0
CMS2_k127_6957130_15 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 413.0
CMS2_k127_6957130_16 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 351.0
CMS2_k127_6957130_17 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 341.0
CMS2_k127_6957130_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 325.0
CMS2_k127_6957130_19 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 296.0
CMS2_k127_6957130_2 Heat shock 70 kDa protein K04043 - - 0.0 1020.0
CMS2_k127_6957130_20 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 285.0
CMS2_k127_6957130_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 280.0
CMS2_k127_6957130_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000371 283.0
CMS2_k127_6957130_23 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001094 255.0
CMS2_k127_6957130_24 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001023 244.0
CMS2_k127_6957130_25 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000001065 233.0
CMS2_k127_6957130_26 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000007991 225.0
CMS2_k127_6957130_27 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000001699 226.0
CMS2_k127_6957130_28 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000007093 210.0
CMS2_k127_6957130_29 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000001602 209.0
CMS2_k127_6957130_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.21e-321 992.0
CMS2_k127_6957130_30 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000000000001831 210.0
CMS2_k127_6957130_31 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 - - - 0.0000000000000000000000000000000000000000000000000000000023 201.0
CMS2_k127_6957130_32 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000001623 194.0
CMS2_k127_6957130_33 peptidase S16, lon K07157 - - 0.000000000000000000000000000000000000000000000000001139 190.0
CMS2_k127_6957130_34 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000009233 160.0
CMS2_k127_6957130_35 oligoketide cyclase lipid transport protein - - - 0.0000000000000000000000000000000000000000837 154.0
CMS2_k127_6957130_36 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000782 142.0
CMS2_k127_6957130_37 PFAM toluene tolerance K07323 - - 0.00000000000000000000000000000000004138 143.0
CMS2_k127_6957130_38 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000000000000000000000004406 132.0
CMS2_k127_6957130_39 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0030674,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0042221,GO:0042802,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045203,GO:0045229,GO:0046677,GO:0050896,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0060090,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00000000000000000000000000000005312 130.0
CMS2_k127_6957130_4 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 2.013e-288 906.0
CMS2_k127_6957130_40 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000009925 116.0
CMS2_k127_6957130_41 CRS1_YhbY K07574 - - 0.0000000000000000000003301 98.0
CMS2_k127_6957130_42 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000002284 99.0
CMS2_k127_6957130_43 Domain of unknown function (DUF4149) - - - 0.00000000000000001489 87.0
CMS2_k127_6957130_44 PFAM blue (type 1) copper domain protein - - - 0.00000000000000002081 90.0
CMS2_k127_6957130_45 glycosyl transferase - - - 0.0000000008194 63.0
CMS2_k127_6957130_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 6.868e-260 803.0
CMS2_k127_6957130_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 3.799e-227 708.0
CMS2_k127_6957130_7 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 1.32e-197 626.0
CMS2_k127_6957130_8 Carbamoyl-phosphate synthetase glutamine chain K01956 GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 603.0
CMS2_k127_6957130_9 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 595.0
CMS2_k127_6959715_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 557.0
CMS2_k127_6959715_1 PFAM EAL domain K21025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 457.0
CMS2_k127_6959715_10 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003623 248.0
CMS2_k127_6959715_11 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000002683 232.0
CMS2_k127_6959715_12 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000027 194.0
CMS2_k127_6959715_13 - - - - 0.000000000000000000000000000000000000000000001301 185.0
CMS2_k127_6959715_14 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000001927 148.0
CMS2_k127_6959715_15 Acetyltransferase (GNAT) domain K03824 - - 0.000000000000000000000000000000001633 136.0
CMS2_k127_6959715_16 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000004875 126.0
CMS2_k127_6959715_2 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 376.0
CMS2_k127_6959715_3 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843,K19810 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 372.0
CMS2_k127_6959715_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 362.0
CMS2_k127_6959715_5 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 350.0
CMS2_k127_6959715_6 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009392 335.0
CMS2_k127_6959715_7 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 325.0
CMS2_k127_6959715_8 Abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 297.0
CMS2_k127_6959715_9 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.0000000000000000000000000000000000000000000000000000000000000000000000000399 256.0
CMS2_k127_6986950_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 470.0
CMS2_k127_6986950_1 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 436.0
CMS2_k127_6986950_2 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000001173 233.0
CMS2_k127_6986950_3 Ribosomal protein L17 K02879 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000256 201.0
CMS2_k127_6986950_4 Cupin domain - - - 0.00000000000000000000000000000000000000000000002871 172.0
CMS2_k127_6986950_5 Thiamine-binding protein - - - 0.0000000000000000000000000000000000365 136.0
CMS2_k127_6986950_6 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000002587 127.0
CMS2_k127_795807_0 Fumarate reductase flavoprotein C-term K00394 - 1.8.99.2 0.0 1262.0
CMS2_k127_795807_1 Glutathione synthase Ribosomal protein S6 modification enzyme - - - 5.241e-208 656.0
CMS2_k127_795807_10 Protein of unknown function (DUF2817) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 371.0
CMS2_k127_795807_11 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 373.0
CMS2_k127_795807_12 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 324.0
CMS2_k127_795807_13 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 315.0
CMS2_k127_795807_14 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 307.0
CMS2_k127_795807_15 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 311.0
CMS2_k127_795807_16 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 291.0
CMS2_k127_795807_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 293.0
CMS2_k127_795807_18 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001732 282.0
CMS2_k127_795807_19 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000457 254.0
CMS2_k127_795807_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 574.0
CMS2_k127_795807_20 Domain of unknown function (DUF4279) - - - 0.00000000000000000000000000000000000000000000000000000000000007525 217.0
CMS2_k127_795807_21 Peptidase membrane zinc metallopeptidase K06973 - - 0.0000000000000000000000000000000000000000000000000000000000007662 218.0
CMS2_k127_795807_22 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000003001 213.0
CMS2_k127_795807_23 - - - - 0.0000000000000000000000000000000000000000000000000000000001837 204.0
CMS2_k127_795807_24 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000004729 169.0
CMS2_k127_795807_25 protein conserved in bacteria K09912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000002592 162.0
CMS2_k127_795807_26 - - - - 0.0000000000000000000000000000000000001044 148.0
CMS2_k127_795807_27 Helix-turn-helix domain - - - 0.000000000000000000000000001314 115.0
CMS2_k127_795807_29 Type III restriction protein res subunit - - - 0.00000000003497 67.0
CMS2_k127_795807_3 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 544.0
CMS2_k127_795807_31 Phage derived protein Gp49-like (DUF891) - - - 0.0001254 46.0
CMS2_k127_795807_4 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 433.0
CMS2_k127_795807_5 acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 434.0
CMS2_k127_795807_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004417 422.0
CMS2_k127_795807_7 6-phosphogluconate dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 417.0
CMS2_k127_795807_8 COG1718 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 407.0
CMS2_k127_795807_9 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 374.0
CMS2_k127_945210_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.0 1243.0
CMS2_k127_945210_1 Required for chromosome condensation and partitioning K03529 - - 0.0 1141.0
CMS2_k127_945210_10 Belongs to the mannose-6-phosphate isomerase type 2 family K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 580.0
CMS2_k127_945210_11 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 574.0
CMS2_k127_945210_12 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 557.0
CMS2_k127_945210_13 Flavin containing amine oxidoreductase K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 554.0
CMS2_k127_945210_14 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 550.0
CMS2_k127_945210_15 PFAM aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005236 511.0
CMS2_k127_945210_16 Belongs to the peptidase S1C family K04772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 469.0
CMS2_k127_945210_17 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 454.0
CMS2_k127_945210_18 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 454.0
CMS2_k127_945210_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 449.0
CMS2_k127_945210_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1035.0
CMS2_k127_945210_20 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 443.0
CMS2_k127_945210_21 DNA recombination protein RmuC K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005421 436.0
CMS2_k127_945210_22 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 407.0
CMS2_k127_945210_23 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 402.0
CMS2_k127_945210_24 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 406.0
CMS2_k127_945210_25 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005325 392.0
CMS2_k127_945210_26 MFS/sugar transport protein K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003941 377.0
CMS2_k127_945210_27 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 368.0
CMS2_k127_945210_28 mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 362.0
CMS2_k127_945210_29 Thioredoxin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 367.0
CMS2_k127_945210_3 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 5.512e-314 974.0
CMS2_k127_945210_30 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 356.0
CMS2_k127_945210_31 pfam php K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007987 353.0
CMS2_k127_945210_32 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 GO:0003674,GO:0003824,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008289,GO:0008689,GO:0008757,GO:0009058,GO:0009108,GO:0009628,GO:0009651,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0042180,GO:0042181,GO:0042538,GO:0043167,GO:0043168,GO:0043431,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0051188,GO:0061542,GO:0071704,GO:1901576,GO:1901611,GO:1901661,GO:1901663 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 347.0
CMS2_k127_945210_33 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 350.0
CMS2_k127_945210_34 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 346.0
CMS2_k127_945210_35 GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 365.0
CMS2_k127_945210_36 PFAM Alpha beta hydrolase K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 340.0
CMS2_k127_945210_37 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007593 329.0
CMS2_k127_945210_38 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 306.0
CMS2_k127_945210_39 Spermine/spermidine synthase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 305.0
CMS2_k127_945210_4 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 8.227e-300 942.0
CMS2_k127_945210_40 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009387 306.0
CMS2_k127_945210_41 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 301.0
CMS2_k127_945210_42 Belongs to the MtfA family K09933 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 297.0
CMS2_k127_945210_43 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002354 283.0
CMS2_k127_945210_44 DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002646 280.0
CMS2_k127_945210_45 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006084 277.0
CMS2_k127_945210_46 PFAM HhH-GPD K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002298 270.0
CMS2_k127_945210_47 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008973 264.0
CMS2_k127_945210_48 short-chain dehydrogenase reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001511 267.0
CMS2_k127_945210_49 High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway K06203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001182 261.0
CMS2_k127_945210_5 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.33e-275 857.0
CMS2_k127_945210_50 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000002224 258.0
CMS2_k127_945210_51 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008289 255.0
CMS2_k127_945210_52 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000004437 239.0
CMS2_k127_945210_53 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000004141 234.0
CMS2_k127_945210_54 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000004823 230.0
CMS2_k127_945210_55 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000218 228.0
CMS2_k127_945210_56 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000001041 222.0
CMS2_k127_945210_57 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000724 224.0
CMS2_k127_945210_58 Protein of unknown function (DUF3833) - - - 0.0000000000000000000000000000000000000000000000000000000000003444 216.0
CMS2_k127_945210_59 ChrR Cupin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000002199 215.0
CMS2_k127_945210_6 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 8.559e-260 818.0
CMS2_k127_945210_60 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000008518 211.0
CMS2_k127_945210_61 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000002132 201.0
CMS2_k127_945210_62 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000009505 180.0
CMS2_k127_945210_63 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000001453 169.0
CMS2_k127_945210_64 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000000000000002195 166.0
CMS2_k127_945210_65 FlgJ-related protein K03796 - - 0.0000000000000000000000000000000000000000005677 162.0
CMS2_k127_945210_66 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000009242 158.0
CMS2_k127_945210_67 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 - - 0.000000000000000000000000000000000000000001902 158.0
CMS2_k127_945210_68 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000325 150.0
CMS2_k127_945210_69 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000006125 147.0
CMS2_k127_945210_7 Participates in both transcription termination and antitermination K02600 - - 2.627e-223 703.0
CMS2_k127_945210_70 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000001962 141.0
CMS2_k127_945210_71 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000006335 134.0
CMS2_k127_945210_72 - - - - 0.000000000000000000000000000000000247 135.0
CMS2_k127_945210_73 Sel1 domain protein repeat-containing protein K07126 - - 0.000000000000000000000000000000001145 145.0
CMS2_k127_945210_74 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0022402,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032506,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 - 0.0000000000000000000000000002454 123.0
CMS2_k127_945210_75 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000003545 114.0
CMS2_k127_945210_76 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000004179 108.0
CMS2_k127_945210_77 SnoaL-like domain - - - 0.00000000000000000000007509 104.0
CMS2_k127_945210_78 cytochrome c5 - - - 0.0000000000000000000001128 107.0
CMS2_k127_945210_79 - - - - 0.00000000000000005291 85.0
CMS2_k127_945210_8 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 5.727e-203 637.0
CMS2_k127_945210_80 competence protein ComEA K02237 - - 0.00000000000002006 78.0
CMS2_k127_945210_81 Belongs to the ParA family K04562 - - 0.000000000002882 77.0
CMS2_k127_945210_82 - - - - 0.0001803 47.0
CMS2_k127_945210_9 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 4.612e-201 634.0