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Overview

ID MAG00417
Name CMS2_bin.24
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order UBA8366
Family JADFVY01
Genus JADFVY01
Species
Assembly information
Completeness (%) 90.95
Contamination (%) 3.25
GC content (%) 63.0
N50 (bp) 28,187
Genome size (bp) 4,250,841

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3918

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1035986_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.954e-273 862.0
CMS2_k127_1035986_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686,K19597 - 3.6.3.54 4.174e-263 834.0
CMS2_k127_1035986_10 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 391.0
CMS2_k127_1035986_11 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 388.0
CMS2_k127_1035986_12 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009586 377.0
CMS2_k127_1035986_13 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 351.0
CMS2_k127_1035986_14 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 332.0
CMS2_k127_1035986_15 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 344.0
CMS2_k127_1035986_16 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 325.0
CMS2_k127_1035986_17 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 323.0
CMS2_k127_1035986_18 TIGRFAM glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 303.0
CMS2_k127_1035986_19 protein conserved in bacteria K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 300.0
CMS2_k127_1035986_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 6.253e-236 739.0
CMS2_k127_1035986_20 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 295.0
CMS2_k127_1035986_21 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000009731 260.0
CMS2_k127_1035986_22 homocysteine K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000584 267.0
CMS2_k127_1035986_23 protein conserved in bacteria K09798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002404 265.0
CMS2_k127_1035986_24 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000824 243.0
CMS2_k127_1035986_25 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000003844 237.0
CMS2_k127_1035986_26 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000001092 209.0
CMS2_k127_1035986_27 helix_turn_helix, mercury resistance K19591 - - 0.00000000000000000000000000000000000000000000000000007544 189.0
CMS2_k127_1035986_28 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000001205 186.0
CMS2_k127_1035986_29 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000004785 111.0
CMS2_k127_1035986_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.269e-225 704.0
CMS2_k127_1035986_30 haloacid dehalogenase-like hydrolase K17686 - 3.6.3.54 0.000000000000008076 77.0
CMS2_k127_1035986_31 COG2825 Outer membrane protein - - - 0.0000000000003305 77.0
CMS2_k127_1035986_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.201e-208 659.0
CMS2_k127_1035986_5 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 605.0
CMS2_k127_1035986_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 502.0
CMS2_k127_1035986_7 COG0303 Molybdopterin biosynthesis enzyme K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 477.0
CMS2_k127_1035986_8 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 442.0
CMS2_k127_1035986_9 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 422.0
CMS2_k127_1047122_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.927e-208 661.0
CMS2_k127_1047122_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 552.0
CMS2_k127_1047122_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 520.0
CMS2_k127_1047122_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 483.0
CMS2_k127_1047122_4 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001203 249.0
CMS2_k127_1047122_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000003259 226.0
CMS2_k127_1047122_6 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000003981 201.0
CMS2_k127_1047122_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000001509 147.0
CMS2_k127_1047122_8 Protein of unknown function (DUF2799) - - - 0.000000000000000000000000001101 122.0
CMS2_k127_1047122_9 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000002184 88.0
CMS2_k127_1083235_0 Belongs to the DNA photolyase family K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 1.607e-200 635.0
CMS2_k127_1083235_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001,K19745 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 473.0
CMS2_k127_1083235_2 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0008825,GO:0009987,GO:0016740,GO:0016741,GO:0030258,GO:0032259,GO:0044237,GO:0044238,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 401.0
CMS2_k127_1088868_0 Belongs to the thiolase family K00626 - 2.3.1.9 3.134e-201 632.0
CMS2_k127_1088868_1 alpha/beta hydrolase fold K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 419.0
CMS2_k127_1088868_2 TIGRFAM acetoacetyl-CoA reductase K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 375.0
CMS2_k127_1088868_3 DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 314.0
CMS2_k127_1088868_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 310.0
CMS2_k127_1088868_5 Catalyzes the synthesis of activated sulfate K00955 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003344 282.0
CMS2_k127_1088868_6 ribosomal protein L11 K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007586 273.0
CMS2_k127_1088868_7 Polyhydroxyalkanoate synthesis repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004567 250.0
CMS2_k127_1088868_8 Tetratricopeptide repeat K12132 - 2.7.11.1 0.00001559 57.0
CMS2_k127_1102948_0 MlrC C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 436.0
CMS2_k127_1102948_1 Bacterial periplasmic substrate-binding proteins K02030,K10022 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 355.0
CMS2_k127_1102948_2 Binding-protein-dependent transport system inner membrane component K02029,K10019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 332.0
CMS2_k127_1102948_3 Binding-protein-dependent transport system inner membrane component K02029,K10020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 321.0
CMS2_k127_1108470_0 pfkB family carbohydrate kinase K16328 - 2.7.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 298.0
CMS2_k127_1108470_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001188 269.0
CMS2_k127_1108470_2 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000002713 197.0
CMS2_k127_111284_0 Peptidase C39, bacteriocin processing K06992 - - 0.00000000000000000000000000000000007439 138.0
CMS2_k127_111284_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000006792 91.0
CMS2_k127_1119653_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 8.829e-300 935.0
CMS2_k127_1119653_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 8.017e-251 785.0
CMS2_k127_1119653_10 ATPase (AAA K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 415.0
CMS2_k127_1119653_11 PFAM Endonuclease Exonuclease phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 372.0
CMS2_k127_1119653_12 hydrolase, family 3 K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 375.0
CMS2_k127_1119653_13 SecD/SecF GG Motif K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006953 371.0
CMS2_k127_1119653_14 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 302.0
CMS2_k127_1119653_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004738 302.0
CMS2_k127_1119653_16 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 299.0
CMS2_k127_1119653_17 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001677 301.0
CMS2_k127_1119653_18 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005911 269.0
CMS2_k127_1119653_19 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007493 276.0
CMS2_k127_1119653_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 589.0
CMS2_k127_1119653_20 COG1994 Zn-dependent proteases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003506 264.0
CMS2_k127_1119653_21 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003569 253.0
CMS2_k127_1119653_22 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000002472 229.0
CMS2_k127_1119653_23 Belongs to the HesB IscA family K15724 - - 0.000000000000000000000000000000000000005344 149.0
CMS2_k127_1119653_24 EamA-like transporter family - - - 0.0000000000000000000000000000000000002463 156.0
CMS2_k127_1119653_25 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000001052 141.0
CMS2_k127_1119653_26 Preprotein translocase subunit YajC K03210 - - 0.00000000000000000000000000000000001147 138.0
CMS2_k127_1119653_27 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 GO:0003674,GO:0005215 - 0.00000000000000000000003431 104.0
CMS2_k127_1119653_28 protein secretion K03116,K03425 GO:0003674,GO:0005215 - 0.0000000000000000006451 90.0
CMS2_k127_1119653_29 Sporulation related domain - - - 0.0000000000000001184 92.0
CMS2_k127_1119653_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 575.0
CMS2_k127_1119653_4 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 548.0
CMS2_k127_1119653_5 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 540.0
CMS2_k127_1119653_6 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 527.0
CMS2_k127_1119653_7 Quinohemoprotein amine dehydrogenase, alpha subunit domain II K08685 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 520.0
CMS2_k127_1119653_8 deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 449.0
CMS2_k127_1119653_9 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 421.0
CMS2_k127_112123_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 3.152e-233 730.0
CMS2_k127_112123_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.036e-229 724.0
CMS2_k127_112123_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 577.0
CMS2_k127_112123_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 581.0
CMS2_k127_112123_4 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000743 496.0
CMS2_k127_112123_5 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 387.0
CMS2_k127_112123_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000001285 131.0
CMS2_k127_112123_7 SEC-C motif - - - 0.00000000000000000000005511 99.0
CMS2_k127_112123_8 Domain of unknown function (DUF1877) - - - 0.000000000000000007649 89.0
CMS2_k127_112123_9 Protein of unknown function (DUF3592) - - - 0.0000000000009827 79.0
CMS2_k127_1145148_0 COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain K03780 - 4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 335.0
CMS2_k127_1145148_1 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007916 284.0
CMS2_k127_1145148_2 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000025 211.0
CMS2_k127_1145148_3 peptidase M48, Ste24p - - - 0.000000000000000000000000000000000000000001426 167.0
CMS2_k127_1145148_4 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000000000001392 154.0
CMS2_k127_1145148_5 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000003102 143.0
CMS2_k127_1145148_6 - - - - 0.0000000000000000000000000000003081 130.0
CMS2_k127_1145148_7 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000003319 109.0
CMS2_k127_1145148_9 COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain K03780 - 4.2.1.32 0.0005401 43.0
CMS2_k127_1163208_0 Domain of unknown function (DUF4132) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 522.0
CMS2_k127_1163208_1 Domain of unknown function (DUF4132) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 360.0
CMS2_k127_1163208_2 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 321.0
CMS2_k127_1163815_0 ABC-type proline glycine betaine transport system permease component K02001 - - 1.125e-271 848.0
CMS2_k127_1163815_1 FAD dependent oxidoreductase K19191 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 448.0
CMS2_k127_1163815_2 Choline/ethanolamine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 366.0
CMS2_k127_1176261_0 PFAM Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 308.0
CMS2_k127_1176261_1 MBOAT, membrane-bound O-acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001698 249.0
CMS2_k127_1176261_2 PFAM AIG2 family protein - - - 0.0000000000000000000000000000009789 126.0
CMS2_k127_1176261_3 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000005475 92.0
CMS2_k127_1176261_4 - - - - 0.000000000000000003556 88.0
CMS2_k127_12084_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.564e-257 801.0
CMS2_k127_12084_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 602.0
CMS2_k127_12084_10 Tetratricopeptide repeat - - - 0.00003695 56.0
CMS2_k127_12084_2 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 503.0
CMS2_k127_12084_3 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 508.0
CMS2_k127_12084_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 323.0
CMS2_k127_12084_5 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 304.0
CMS2_k127_12084_6 - - - - 0.00000000000000000000000000000000000000000000000000002324 207.0
CMS2_k127_12084_7 Domain of unknown function (DUF4153) - - - 0.00000000000000000000000000000000000000000007063 180.0
CMS2_k127_12084_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000005328 132.0
CMS2_k127_12084_9 Peptidase S24-like K03100 - 3.4.21.89 0.000000000000000001119 97.0
CMS2_k127_1218446_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 2.412e-217 681.0
CMS2_k127_1218446_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 455.0
CMS2_k127_1218446_2 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 404.0
CMS2_k127_1218446_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 323.0
CMS2_k127_1218446_4 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004466 273.0
CMS2_k127_1218446_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001858 263.0
CMS2_k127_1218446_6 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003515 266.0
CMS2_k127_1218446_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008113 250.0
CMS2_k127_1218446_8 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009915 250.0
CMS2_k127_1218446_9 transport system small permease component - - - 0.000000000000000000000000000000000000000000000000000000000000001542 223.0
CMS2_k127_1225881_0 AcrB/AcrD/AcrF family - - - 0.0 1460.0
CMS2_k127_1225881_1 FAD dependent oxidoreductase - - - 1.502e-238 743.0
CMS2_k127_1225881_10 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 414.0
CMS2_k127_1225881_11 Catalyzes the carbon skeleton rearrangement of L- glutamate to L-threo-3-methylaspartate ((2S,3S)-3- methylaspartate) K19268 - 5.4.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 418.0
CMS2_k127_1225881_12 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 410.0
CMS2_k127_1225881_13 branched-chain amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 342.0
CMS2_k127_1225881_14 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 322.0
CMS2_k127_1225881_15 amino acid ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 320.0
CMS2_k127_1225881_16 Glutathione S-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 314.0
CMS2_k127_1225881_17 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 316.0
CMS2_k127_1225881_18 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 318.0
CMS2_k127_1225881_19 taurine catabolism dioxygenase K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 303.0
CMS2_k127_1225881_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.801e-236 743.0
CMS2_k127_1225881_20 LysR substrate binding domain K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009372 299.0
CMS2_k127_1225881_21 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 287.0
CMS2_k127_1225881_22 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001563 291.0
CMS2_k127_1225881_23 Nucleoside 2-deoxyribosyltransferase YtoQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002901 242.0
CMS2_k127_1225881_24 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000008768 241.0
CMS2_k127_1225881_25 Co Zn Cd efflux system component - - - 0.000000000000000000000000000000000000000000000000000000000000000000152 236.0
CMS2_k127_1225881_26 transcriptional regulator K02624 - - 0.0000000000000000000000000000000000000000000000000000000000000001443 230.0
CMS2_k127_1225881_27 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000000001549 224.0
CMS2_k127_1225881_28 Catalyzes the carbon skeleton rearrangement of L- glutamate to L-threo-3-methylaspartate ((2S,3S)-3- methylaspartate) K01846 - 5.4.99.1 0.000000000000000000000000000000000000000000000002805 178.0
CMS2_k127_1225881_29 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000000000000000006466 177.0
CMS2_k127_1225881_3 Protein conserved in bacteria K07793 - - 1.406e-212 670.0
CMS2_k127_1225881_30 Creatinase/Prolidase N-terminal domain K08688 - 3.5.3.3 0.00000000000000000000000000000000000000000003382 161.0
CMS2_k127_1225881_31 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000004949 166.0
CMS2_k127_1225881_32 - - - - 0.00000000000000000000000000000000000000002514 158.0
CMS2_k127_1225881_33 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000127 152.0
CMS2_k127_1225881_34 signal transduction histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000003246 154.0
CMS2_k127_1225881_35 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000189 126.0
CMS2_k127_1225881_36 Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome - - - 0.00000000000000000000000000003275 133.0
CMS2_k127_1225881_37 membrane transporter protein K07090 - - 0.0000000000000000000000000001799 133.0
CMS2_k127_1225881_38 Belongs to the succinate malate CoA ligase beta subunit family K01903 - 6.2.1.5 0.0000000000000000000003573 98.0
CMS2_k127_1225881_39 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000866 96.0
CMS2_k127_1225881_4 COG1012 NAD-dependent aldehyde dehydrogenases K13922,K15515 - 1.2.1.81,1.2.1.87 9.869e-201 635.0
CMS2_k127_1225881_40 Histidine kinase - - - 0.00000000000000000736 88.0
CMS2_k127_1225881_5 With LivFGHM is involved in the high affinity leucine transport K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 477.0
CMS2_k127_1225881_6 COG0826 Collagenase and related proteases K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 470.0
CMS2_k127_1225881_7 TIGRFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 453.0
CMS2_k127_1225881_8 Creatinase/Prolidase N-terminal domain K01271,K08688 - 3.4.13.9,3.5.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 432.0
CMS2_k127_1225881_9 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 424.0
CMS2_k127_127607_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 4.799e-204 642.0
CMS2_k127_127607_1 Acyl transferase domain K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 426.0
CMS2_k127_127607_10 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 287.0
CMS2_k127_127607_11 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000264 173.0
CMS2_k127_127607_12 Secreted protein - - - 0.0000000000000000000000000000000000000000000001595 180.0
CMS2_k127_127607_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000001327 137.0
CMS2_k127_127607_14 PAS domain - - - 0.0000000000001164 79.0
CMS2_k127_127607_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 375.0
CMS2_k127_127607_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 345.0
CMS2_k127_127607_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 335.0
CMS2_k127_127607_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 330.0
CMS2_k127_127607_6 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 331.0
CMS2_k127_127607_7 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 310.0
CMS2_k127_127607_8 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 296.0
CMS2_k127_127607_9 Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 297.0
CMS2_k127_1317718_0 Belongs to the GcvT family K00302 - 1.5.3.1 0.0 1251.0
CMS2_k127_1317718_1 FAD dependent oxidoreductase central domain - - - 0.0 1199.0
CMS2_k127_1317718_10 Spermidine synthase tetramerisation domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 419.0
CMS2_k127_1317718_11 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 395.0
CMS2_k127_1317718_12 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K21826 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 382.0
CMS2_k127_1317718_13 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 384.0
CMS2_k127_1317718_14 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 346.0
CMS2_k127_1317718_15 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 322.0
CMS2_k127_1317718_16 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 319.0
CMS2_k127_1317718_17 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 301.0
CMS2_k127_1317718_18 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004257 271.0
CMS2_k127_1317718_19 Class ii aldolase K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000003696 269.0
CMS2_k127_1317718_2 Trimethylamine methyltransferase K14083 - 2.1.1.250 1.785e-243 763.0
CMS2_k127_1317718_20 Methionine synthase B12-binding module cap domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001688 253.0
CMS2_k127_1317718_21 HD phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002092 243.0
CMS2_k127_1317718_22 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001349 244.0
CMS2_k127_1317718_23 Wd-40 repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000001614 244.0
CMS2_k127_1317718_24 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000006469 238.0
CMS2_k127_1317718_25 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.00000000000000000000000000000000000000000000000000000000000001474 220.0
CMS2_k127_1317718_26 L-lactate permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000297 230.0
CMS2_k127_1317718_27 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.00000000000000000000000000000000000000000000000000000000000935 213.0
CMS2_k127_1317718_28 AzlC protein - - - 0.0000000000000000000000000000000000000000000000000000000008947 210.0
CMS2_k127_1317718_29 Pfam Response regulator receiver - - - 0.000000000000000000000000000000000000000000000003974 176.0
CMS2_k127_1317718_3 response regulator K02481 - - 6.445e-226 707.0
CMS2_k127_1317718_30 GumN family K09973 - - 0.000000000000000000000000000000000000000000000005917 183.0
CMS2_k127_1317718_31 Sarcosine oxidase, gamma subunit family K00305 - 1.5.3.1 0.0000000000000000000000000000000000000000000000754 175.0
CMS2_k127_1317718_32 Sarcosine oxidase, delta subunit family K00304 - 1.5.3.1 0.0000000000000000000000000000000000001369 142.0
CMS2_k127_1317718_33 - - - - 0.0000000000000000000000000000000000013 142.0
CMS2_k127_1317718_34 Protein of unknown function (DUF1491) - - - 0.00000000000000000000000000000000004394 141.0
CMS2_k127_1317718_35 Protein of unknown function (DUF805) - - - 0.000000000000000000000000000000001131 134.0
CMS2_k127_1317718_36 Hemerythrin HHE cation binding domain K07216 - - 0.00000000000000000000003164 104.0
CMS2_k127_1317718_37 Sel1 domain protein repeat-containing protein K07126,K13582 - - 0.0000000000000000000000372 109.0
CMS2_k127_1317718_39 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000000001437 89.0
CMS2_k127_1317718_4 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 8.334e-215 678.0
CMS2_k127_1317718_5 FAD dependent oxidoreductase K00303 - 1.5.3.1 3.168e-212 664.0
CMS2_k127_1317718_6 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 593.0
CMS2_k127_1317718_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 519.0
CMS2_k127_1317718_8 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 512.0
CMS2_k127_1317718_9 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 445.0
CMS2_k127_1341424_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 3e-323 998.0
CMS2_k127_1341424_1 ABC-type multidrug transport system, ATPase and permease K06147 - - 5.161e-236 740.0
CMS2_k127_1341424_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 348.0
CMS2_k127_1341424_3 protein conserved in bacteria K09987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002341 258.0
CMS2_k127_1341424_4 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000000000000000000000000000000013 193.0
CMS2_k127_1341424_5 Hsp20/alpha crystallin family K04080 - - 0.0000000000000000000000000000000000000000000001807 172.0
CMS2_k127_1341424_6 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000004468 170.0
CMS2_k127_1341424_7 Ribosomal protein L31 K02909 - - 0.000000000000000000000000000000000004064 140.0
CMS2_k127_1341424_8 Protein of unknown function (DUF1465) K13592 - - 0.00000000000000000000001459 106.0
CMS2_k127_1341424_9 Protein of unknown function (DUF1192) - - - 0.00000002256 58.0
CMS2_k127_1343429_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 498.0
CMS2_k127_1343429_1 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000008864 214.0
CMS2_k127_1343429_2 FCD - - - 0.000000000000000000000000000000000000000000000000005151 189.0
CMS2_k127_1343429_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000003291 162.0
CMS2_k127_1355790_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1648.0
CMS2_k127_1355790_1 4Fe-4S binding domain - - - 8.323e-268 844.0
CMS2_k127_1355790_10 TIGRFAM formate dehydrogenase region TAT target - - - 0.000005798 51.0
CMS2_k127_1355790_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006534 407.0
CMS2_k127_1355790_3 4Fe-4S dicluster domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 318.0
CMS2_k127_1355790_4 Nitrate reductase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000001371 241.0
CMS2_k127_1355790_5 Protein of unknown function (DUF3305) - - - 0.0000000000000000000000000000000000000001948 156.0
CMS2_k127_1355790_6 Gram-negative porin K08720 - - 0.000000000000000000000000009131 119.0
CMS2_k127_1355790_7 Protein of unknown function (DUF3306) - - - 0.000000000000000000006908 101.0
CMS2_k127_1355790_8 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000001964 89.0
CMS2_k127_1355790_9 - - - - 0.000004001 54.0
CMS2_k127_1364071_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 524.0
CMS2_k127_1364071_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 409.0
CMS2_k127_1364071_10 Cytochrome c K08738 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009987,GO:0015979,GO:0016020,GO:0044237,GO:0044464,GO:0071944 - 0.000000000000000000000006598 106.0
CMS2_k127_1364071_11 Protein of unknown function (DUF1150) - - - 0.000000009923 59.0
CMS2_k127_1364071_12 Peptidase propeptide and YPEB domain - - - 0.00000009073 61.0
CMS2_k127_1364071_2 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 349.0
CMS2_k127_1364071_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002809 263.0
CMS2_k127_1364071_4 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009814 240.0
CMS2_k127_1364071_5 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000000000000000000000000000007353 201.0
CMS2_k127_1364071_6 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000002752 169.0
CMS2_k127_1364071_7 cytochrome K08738 - - 0.0000000000000000000000000000000000000002654 154.0
CMS2_k127_1364071_8 17 kDa outer membrane surface antigen - - - 0.000000000000000000000000000000000000001261 162.0
CMS2_k127_1364071_9 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000004359 141.0
CMS2_k127_1367571_0 FAD dependent oxidoreductase central domain - - - 0.0 1184.0
CMS2_k127_1367571_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 0.0 1020.0
CMS2_k127_1367571_10 Belongs to the enoyl-CoA hydratase isomerase family K08299 - 4.2.1.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 404.0
CMS2_k127_1367571_11 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 343.0
CMS2_k127_1367571_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005317 255.0
CMS2_k127_1367571_13 Alpha beta hydrolase K01066 - - 0.00000000000000000000000000000000000000000000000000000001275 218.0
CMS2_k127_1367571_14 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000002845 181.0
CMS2_k127_1367571_15 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000003207 164.0
CMS2_k127_1367571_16 PFAM Excinuclease ABC, C subunit K07461 - - 0.0000000000000000000000000000000000000002877 151.0
CMS2_k127_1367571_17 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000002534 139.0
CMS2_k127_1367571_18 Protein conserved in bacteria - - - 0.00000000000000000000000000000003381 133.0
CMS2_k127_1367571_19 - - - - 0.000000000000001515 87.0
CMS2_k127_1367571_2 Heat shock 70 kDa protein K04043 - - 2.092e-265 830.0
CMS2_k127_1367571_20 diguanylate cyclase K13069 - 2.7.7.65 0.0000000000000349 82.0
CMS2_k127_1367571_3 CoA binding domain - - - 1.687e-213 694.0
CMS2_k127_1367571_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.621e-198 623.0
CMS2_k127_1367571_5 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 548.0
CMS2_k127_1367571_6 COG1960 Acyl-CoA dehydrogenases K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 441.0
CMS2_k127_1367571_7 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine K17735 - 1.1.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 427.0
CMS2_k127_1367571_8 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 427.0
CMS2_k127_1367571_9 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 409.0
CMS2_k127_1391887_0 - - - - 0.0 1092.0
CMS2_k127_1391887_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 593.0
CMS2_k127_1391887_2 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 548.0
CMS2_k127_1391887_3 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 445.0
CMS2_k127_1391887_4 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 392.0
CMS2_k127_1391887_5 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 362.0
CMS2_k127_1391887_6 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000337 196.0
CMS2_k127_1391887_7 Protein of unknown function (DUF2948) - - - 0.00000000000000000000000000000000006478 139.0
CMS2_k127_1432005_0 CoA-binding domain protein K09181 - - 2.281e-283 903.0
CMS2_k127_1432005_1 GTP-binding protein TypA K06207 - - 1.237e-277 866.0
CMS2_k127_1432005_10 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000006141 232.0
CMS2_k127_1432005_11 Appr-1-p processing domain protein - - - 0.000000000000000000000000000000000000000000000000000000002839 209.0
CMS2_k127_1432005_12 Etoposide-induced protein 2.4 (EI24) - - - 0.000000000000000000000000000000000000000000000000000008222 198.0
CMS2_k127_1432005_13 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000000000000000000000002494 174.0
CMS2_k127_1432005_14 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000004422 143.0
CMS2_k127_1432005_15 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000004552 126.0
CMS2_k127_1432005_16 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000002068 126.0
CMS2_k127_1432005_17 - - - - 0.00000000002833 71.0
CMS2_k127_1432005_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 566.0
CMS2_k127_1432005_3 COG0477 Permeases of the major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 528.0
CMS2_k127_1432005_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 499.0
CMS2_k127_1432005_5 COG0524 Sugar kinases, ribokinase family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 392.0
CMS2_k127_1432005_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 343.0
CMS2_k127_1432005_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 340.0
CMS2_k127_1432005_8 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 285.0
CMS2_k127_1432005_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000387 241.0
CMS2_k127_1440776_0 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 354.0
CMS2_k127_1440776_1 Bacteriophage head to tail connecting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008533 291.0
CMS2_k127_1440776_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003354 263.0
CMS2_k127_1440776_3 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.00000000000000000000000000000000000000000000000000115 190.0
CMS2_k127_1440776_4 - - - - 0.00000000000000000000000000005348 124.0
CMS2_k127_1440776_6 - - - - 0.000000000000000002138 98.0
CMS2_k127_1440776_7 - - - - 0.0000000002056 72.0
CMS2_k127_1440776_8 - - - - 0.000000001364 70.0
CMS2_k127_1455382_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1236.0
CMS2_k127_1455382_1 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 2.833e-231 729.0
CMS2_k127_1455382_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 588.0
CMS2_k127_1455382_3 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 368.0
CMS2_k127_1455382_4 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 320.0
CMS2_k127_1455382_5 ISXO2-like transposase domain - - - 0.00000000000000000000000000000000000000000000000000000000000001592 217.0
CMS2_k127_1455534_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.339e-221 693.0
CMS2_k127_1455534_1 phosphomannomutase K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 574.0
CMS2_k127_1455534_10 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000001766 159.0
CMS2_k127_1455534_11 Protein of unknown function (DUF1489) - - - 0.0000000000000000000000000000000000000008659 157.0
CMS2_k127_1455534_12 Response regulator receiver - - - 0.00000000000000000000000000000000007756 141.0
CMS2_k127_1455534_13 Belongs to the ompA family - - - 0.00000000000000000000000000003667 127.0
CMS2_k127_1455534_14 DnaJ molecular chaperone homology domain - - - 0.00000000000000000000000000007351 126.0
CMS2_k127_1455534_15 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000001359 98.0
CMS2_k127_1455534_16 Belongs to the ompA family - - - 0.0000000000000000000004427 103.0
CMS2_k127_1455534_17 Outer membrane protein beta-barrel domain - - - 0.0000000004982 69.0
CMS2_k127_1455534_18 Protein of unknown function (DUF2927) - - - 0.000004721 57.0
CMS2_k127_1455534_2 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 435.0
CMS2_k127_1455534_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 421.0
CMS2_k127_1455534_4 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 409.0
CMS2_k127_1455534_5 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007746 408.0
CMS2_k127_1455534_6 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 331.0
CMS2_k127_1455534_7 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 310.0
CMS2_k127_1455534_8 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001245 283.0
CMS2_k127_1455534_9 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000008427 241.0
CMS2_k127_1464408_0 Glycine cleavage T-protein C-terminal barrel domain K00302 - 1.5.3.1 0.0 1208.0
CMS2_k127_1464408_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.028e-266 833.0
CMS2_k127_1464408_10 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 356.0
CMS2_k127_1464408_11 branched-chain amino acid transport K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 334.0
CMS2_k127_1464408_12 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 298.0
CMS2_k127_1464408_13 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000008117 199.0
CMS2_k127_1464408_14 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000004021 191.0
CMS2_k127_1464408_15 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000012 193.0
CMS2_k127_1464408_16 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000004011 173.0
CMS2_k127_1464408_17 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000001507 157.0
CMS2_k127_1464408_18 Sarcosine oxidase, delta subunit K00304 - 1.5.3.1 0.0000000000000000000000000000000000109 138.0
CMS2_k127_1464408_19 Sarcosine oxidase, gamma subunit K00305,K22087 - 1.5.3.1,1.5.99.5 0.000000000000000000000000004351 119.0
CMS2_k127_1464408_2 Sarcosine oxidase beta subunit K00303 - 1.5.3.1 6.232e-200 633.0
CMS2_k127_1464408_3 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 486.0
CMS2_k127_1464408_4 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 452.0
CMS2_k127_1464408_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 432.0
CMS2_k127_1464408_6 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003322 429.0
CMS2_k127_1464408_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 387.0
CMS2_k127_1464408_8 DNA-3-methyladenine glycosylase I K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 361.0
CMS2_k127_1464408_9 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 366.0
CMS2_k127_148126_0 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 - 1.2.4.2 0.0 1331.0
CMS2_k127_148126_1 This protein is involved in the repair of mismatches in DNA K03555 - - 0.0 1187.0
CMS2_k127_148126_10 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 505.0
CMS2_k127_148126_11 COG2030 Acyl dehydratase K14449 - 4.2.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 477.0
CMS2_k127_148126_12 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 456.0
CMS2_k127_148126_13 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 428.0
CMS2_k127_148126_14 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 414.0
CMS2_k127_148126_15 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 421.0
CMS2_k127_148126_16 AFG1-like ATPase K06916 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 410.0
CMS2_k127_148126_17 phosphate regulon transcriptional regulatory protein PhoB K07657,K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 319.0
CMS2_k127_148126_18 involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 309.0
CMS2_k127_148126_19 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004786 276.0
CMS2_k127_148126_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0 1151.0
CMS2_k127_148126_20 EamA-like transporter family K05786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001037 257.0
CMS2_k127_148126_21 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000006085 252.0
CMS2_k127_148126_22 involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000007422 236.0
CMS2_k127_148126_23 - - - - 0.00000000000000000000000000000000000000000000000000001804 200.0
CMS2_k127_148126_24 Putative FMN-binding domain K07734 - - 0.0000000000000000000000000000000000000000000000000002235 191.0
CMS2_k127_148126_25 succinate dehydrogenase K00241 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000002047 154.0
CMS2_k127_148126_26 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000001543 154.0
CMS2_k127_148126_27 succinate dehydrogenase K00242 - - 0.00000000000000000000000000000000002039 139.0
CMS2_k127_148126_28 transcriptional regulator - - - 0.00000000000000000000000000000003977 134.0
CMS2_k127_148126_29 - - - - 0.00000000000000000000000000000005476 136.0
CMS2_k127_148126_3 malic enzyme K00029 - 1.1.1.40 0.0 1134.0
CMS2_k127_148126_30 - - - - 0.000000000000000000000000000003478 134.0
CMS2_k127_148126_4 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1013.0
CMS2_k127_148126_5 SAF - - - 3.002e-194 616.0
CMS2_k127_148126_6 Domain of unknown function (DUF3333) K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 541.0
CMS2_k127_148126_7 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 538.0
CMS2_k127_148126_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 511.0
CMS2_k127_148126_9 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 516.0
CMS2_k127_1484046_0 Long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 353.0
CMS2_k127_1484046_1 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001434 251.0
CMS2_k127_1484046_2 Permease MlaE K02066 - - 0.000000000000000000000000000000004129 135.0
CMS2_k127_1484046_3 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000006386 125.0
CMS2_k127_1484046_4 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.000002943 53.0
CMS2_k127_1494487_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates - - - 6.801e-283 887.0
CMS2_k127_1494487_1 Belongs to the 5'-nucleotidase family K17224 - - 5.898e-265 825.0
CMS2_k127_1494487_10 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 382.0
CMS2_k127_1494487_11 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 341.0
CMS2_k127_1494487_12 long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 337.0
CMS2_k127_1494487_13 Cytochrome c biogenesis protein K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 312.0
CMS2_k127_1494487_14 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 312.0
CMS2_k127_1494487_15 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008037 314.0
CMS2_k127_1494487_16 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 307.0
CMS2_k127_1494487_17 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 312.0
CMS2_k127_1494487_18 Transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 299.0
CMS2_k127_1494487_19 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000282 289.0
CMS2_k127_1494487_2 Cytochrome c554 and c-prime - - - 1.012e-219 700.0
CMS2_k127_1494487_20 Bacterial lipid A biosynthesis acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 288.0
CMS2_k127_1494487_21 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005603 274.0
CMS2_k127_1494487_22 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003316 266.0
CMS2_k127_1494487_23 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000003933 246.0
CMS2_k127_1494487_24 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000006314 229.0
CMS2_k127_1494487_25 Glycosyl Transferase - - - 0.000000000000000000000000000000000000000000000000000000000000004066 233.0
CMS2_k127_1494487_26 - - - - 0.00000000000000000000000000000000000000000000000000000000001405 217.0
CMS2_k127_1494487_27 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000003524 204.0
CMS2_k127_1494487_28 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000000007915 198.0
CMS2_k127_1494487_29 gamma-carboxymuconolactone decarboxylase subunit K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000003458 189.0
CMS2_k127_1494487_3 Pyridoxal-phosphate dependent enzyme K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 559.0
CMS2_k127_1494487_30 Thioredoxin-like domain - - - 0.00000000000000000000000000000000000000000000000000007142 194.0
CMS2_k127_1494487_31 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000002852 190.0
CMS2_k127_1494487_32 cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000005062 174.0
CMS2_k127_1494487_33 CHAP domain - - - 0.00000000000000000000000000000000000000000007637 167.0
CMS2_k127_1494487_34 Cytochrome c - - - 0.0000000000000000000000000000000000000000001994 174.0
CMS2_k127_1494487_35 Haem-degrading - - - 0.0000000000000000000000000000000000000000002616 163.0
CMS2_k127_1494487_36 Sulphur oxidation protein SoxZ - - - 0.00000000000000000000000000000000000002592 146.0
CMS2_k127_1494487_37 Beta-ketoacyl synthase, N-terminal domain - - - 0.00000000000000000000000000000000000003271 153.0
CMS2_k127_1494487_38 sulfur oxidation protein (SoxY) K17226 - - 0.00000000000000000000000000000000000006359 150.0
CMS2_k127_1494487_39 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000005436 144.0
CMS2_k127_1494487_4 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 453.0
CMS2_k127_1494487_40 Planctomycete cytochrome C - - - 0.00000000000000000000000000000000003216 139.0
CMS2_k127_1494487_41 Regulatory protein SoxS - - - 0.00000000000000000000000000000001389 132.0
CMS2_k127_1494487_42 DUF218 domain - - - 0.0000000000000000000000000000001766 132.0
CMS2_k127_1494487_43 - - - - 0.000000000000000000000000000014 122.0
CMS2_k127_1494487_44 - - - - 0.000000000000000000000000004529 115.0
CMS2_k127_1494487_45 Thioesterase superfamily K01075 - 3.1.2.23 0.0000000000000000000000003745 110.0
CMS2_k127_1494487_46 acyl carrier protein K02078 - - 0.000000000000000000000007231 111.0
CMS2_k127_1494487_47 PFAM regulatory protein ArsR - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000005738 104.0
CMS2_k127_1494487_48 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000001109 111.0
CMS2_k127_1494487_49 BioY family K03523 - - 0.000000000000000000001083 96.0
CMS2_k127_1494487_5 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 454.0
CMS2_k127_1494487_50 dehydratase - - - 0.000000000000000000008089 99.0
CMS2_k127_1494487_51 Outer membrane lipoprotein carrier protein LolA - - - 0.00000000000000000003799 100.0
CMS2_k127_1494487_52 cytochrome C - - - 0.000000000000000001029 98.0
CMS2_k127_1494487_53 Universal stress protein family - - - 0.00000000000000007 87.0
CMS2_k127_1494487_54 Pfam cytochrome c - - - 0.00000000000001003 77.0
CMS2_k127_1494487_55 - - - - 0.00000000001173 76.0
CMS2_k127_1494487_57 PFAM Cytochrome c, class I - - - 0.000000001141 64.0
CMS2_k127_1494487_6 Beta-ketoacyl synthase, N-terminal domain K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 435.0
CMS2_k127_1494487_60 epoxide hydrolase K01253 - 3.3.2.9 0.0000007238 51.0
CMS2_k127_1494487_7 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 420.0
CMS2_k127_1494487_8 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 408.0
CMS2_k127_1494487_9 MMPL family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 411.0
CMS2_k127_1495960_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.524e-283 876.0
CMS2_k127_1495960_1 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 426.0
CMS2_k127_1495960_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 301.0
CMS2_k127_1495960_3 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000008798 109.0
CMS2_k127_1498986_0 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 394.0
CMS2_k127_1498986_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000003603 201.0
CMS2_k127_1541149_0 E1-E2 ATPase K17686 - 3.6.3.54 0.0 1341.0
CMS2_k127_1541149_1 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 3.583e-196 616.0
CMS2_k127_1541149_2 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 437.0
CMS2_k127_1541149_3 helix_turn_helix, mercury resistance K19591 - - 0.00000000000000000000000000000000000000000000000000000000000000000001009 234.0
CMS2_k127_1541149_4 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000002465 146.0
CMS2_k127_1541149_5 Heavy-metal-associated domain K07213 - - 0.00000000000000000002004 93.0
CMS2_k127_157718_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1280.0
CMS2_k127_157718_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 4.007e-251 787.0
CMS2_k127_157718_10 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003641 256.0
CMS2_k127_157718_11 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000116 170.0
CMS2_k127_157718_12 ACT domain - - - 0.000000000000000000000000000000000000009791 151.0
CMS2_k127_157718_13 PIN domain K07065 - - 0.000000000000000000000000007014 115.0
CMS2_k127_157718_14 SOS response K14160 - - 0.000000000000000000000000007554 119.0
CMS2_k127_157718_15 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000002283 105.0
CMS2_k127_157718_16 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000002538 74.0
CMS2_k127_157718_17 - K21495 - - 0.00000003535 57.0
CMS2_k127_157718_18 - - - - 0.000001692 57.0
CMS2_k127_157718_2 Belongs to the arginase family K01480,K18459 - 3.5.3.11,3.5.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 480.0
CMS2_k127_157718_3 RNA polymerase sigma K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 454.0
CMS2_k127_157718_4 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 444.0
CMS2_k127_157718_5 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 435.0
CMS2_k127_157718_6 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 410.0
CMS2_k127_157718_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 410.0
CMS2_k127_157718_8 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 376.0
CMS2_k127_157718_9 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 364.0
CMS2_k127_1755229_0 Belongs to the UbiD family K03182 - 4.1.1.98 1.742e-293 904.0
CMS2_k127_1755229_1 peptidase U62, modulator of DNA gyrase K03568 - - 1.563e-233 730.0
CMS2_k127_1755229_10 - - - - 0.000000000000000000000000000000000000000000000005123 180.0
CMS2_k127_1755229_11 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000006611 182.0
CMS2_k127_1755229_12 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000000000001356 164.0
CMS2_k127_1755229_13 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000001266 159.0
CMS2_k127_1755229_14 Domain of unknown function (DUF4170) - - - 0.000000000000000000000000000000000000001511 150.0
CMS2_k127_1755229_15 - - - - 0.00000000000000000000000000000000000002632 154.0
CMS2_k127_1755229_16 AMP binding - - - 0.00000000000000000000000000895 115.0
CMS2_k127_1755229_17 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000005858 108.0
CMS2_k127_1755229_18 - - - - 0.0000000000000000000000006509 108.0
CMS2_k127_1755229_2 glutamate--cysteine ligase K01919 - 6.3.2.2 1.359e-214 674.0
CMS2_k127_1755229_3 Zn-dependent proteases and their inactivated homologs K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009303 540.0
CMS2_k127_1755229_4 Protein of unknown function (DUF3422) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 458.0
CMS2_k127_1755229_5 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 410.0
CMS2_k127_1755229_6 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 390.0
CMS2_k127_1755229_7 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 318.0
CMS2_k127_1755229_8 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008582 281.0
CMS2_k127_1755229_9 Aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000000000009697 186.0
CMS2_k127_1772903_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18989 - - 0.0 1229.0
CMS2_k127_1772903_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 317.0
CMS2_k127_1772903_10 Endoribonuclease L-PSP K09021 - - 0.00000000000000000000000000000000000000000000000000000001647 201.0
CMS2_k127_1772903_11 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000001967 175.0
CMS2_k127_1772903_12 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000003049 171.0
CMS2_k127_1772903_13 Cytochrome C' - - - 0.00000000000000000001209 100.0
CMS2_k127_1772903_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 311.0
CMS2_k127_1772903_3 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 311.0
CMS2_k127_1772903_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 306.0
CMS2_k127_1772903_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 293.0
CMS2_k127_1772903_6 protein containing LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005163 267.0
CMS2_k127_1772903_7 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000005258 227.0
CMS2_k127_1772903_8 COG0558 Phosphatidylglycerophosphate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000008006 219.0
CMS2_k127_1772903_9 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000001005 209.0
CMS2_k127_1836948_0 Adenylate cyclase - - - 4.984e-194 619.0
CMS2_k127_1836948_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 544.0
CMS2_k127_1836948_2 COG1910, Periplasmic molybdate-binding protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 354.0
CMS2_k127_1836948_3 Transcriptional regulator K03719 - - 0.000000000000000000000000000000000000000000000000009445 184.0
CMS2_k127_1836948_4 racemase activity, acting on amino acids and derivatives - - - 0.00002035 53.0
CMS2_k127_1855168_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1272.0
CMS2_k127_1855168_1 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 428.0
CMS2_k127_1855168_10 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000002374 175.0
CMS2_k127_1855168_11 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000004582 162.0
CMS2_k127_1855168_12 TIGRFAM cobalt transporter subunit CbtA - - - 0.0000000000000000000000000000000000000000006872 164.0
CMS2_k127_1855168_13 DNA repair protein MmcB-like - - - 0.000000000000000000000000000000000000003815 150.0
CMS2_k127_1855168_14 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.0000000000000000000000000000188 121.0
CMS2_k127_1855168_15 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.00000000000000000000000000008459 116.0
CMS2_k127_1855168_16 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.0000000000000000000000000003493 118.0
CMS2_k127_1855168_17 Zinc-finger domain - - - 0.0000000000000000000004599 96.0
CMS2_k127_1855168_18 PAS domain - - - 0.000000000000000006448 90.0
CMS2_k127_1855168_19 Probable cobalt transporter subunit (CbtB) - - - 0.000000005254 61.0
CMS2_k127_1855168_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005716 423.0
CMS2_k127_1855168_3 Lysophospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 322.0
CMS2_k127_1855168_4 Nitrile hydratase, alpha chain K01721,K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002567 279.0
CMS2_k127_1855168_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000165 277.0
CMS2_k127_1855168_6 PFAM Response regulator receiver domain K15012 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005229 269.0
CMS2_k127_1855168_7 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000001576 247.0
CMS2_k127_1855168_8 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000006634 203.0
CMS2_k127_1855168_9 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.00000000000000000000000000000000000000000000004643 174.0
CMS2_k127_1878113_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 8.689e-248 791.0
CMS2_k127_1878113_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.014e-223 702.0
CMS2_k127_1878113_10 Zn-dependent protease, contains TPR repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 372.0
CMS2_k127_1878113_11 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 340.0
CMS2_k127_1878113_12 beta-fructofuranosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 318.0
CMS2_k127_1878113_13 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 331.0
CMS2_k127_1878113_14 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 308.0
CMS2_k127_1878113_15 Maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005238 289.0
CMS2_k127_1878113_16 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 304.0
CMS2_k127_1878113_17 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001227 293.0
CMS2_k127_1878113_18 Glycosyl transferase, group 1 K16150 - 2.4.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002989 278.0
CMS2_k127_1878113_19 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000002441 223.0
CMS2_k127_1878113_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 4.51e-221 692.0
CMS2_k127_1878113_20 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000003717 201.0
CMS2_k127_1878113_21 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000387 205.0
CMS2_k127_1878113_22 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.0000000000000000000000000000000000000000000000000009923 198.0
CMS2_k127_1878113_23 Thioredoxin - - - 0.0000000000000000000000000000000000000000000002404 183.0
CMS2_k127_1878113_24 Lipid A 3-O-deacylase (PagL) K12976 - - 0.000000000000000000000000000000000000000000002832 171.0
CMS2_k127_1878113_25 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000297 171.0
CMS2_k127_1878113_26 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000001919 160.0
CMS2_k127_1878113_27 - - - - 0.0000000000000000000000000000000000004649 143.0
CMS2_k127_1878113_28 General secretion pathway protein H K02457 - - 0.000000000000000000000000000001644 125.0
CMS2_k127_1878113_29 General secretion pathway protein K02461 - - 0.00000000000000000000000000003441 133.0
CMS2_k127_1878113_3 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 3.296e-219 700.0
CMS2_k127_1878113_30 General secretion pathway protein M K02462 - - 0.000000000000000000000003739 111.0
CMS2_k127_1878113_31 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000006092 115.0
CMS2_k127_1878113_33 Gram-negative porin K08720 - - 0.00000000000000000000002762 114.0
CMS2_k127_1878113_34 Prokaryotic N-terminal methylation motif K02459 - - 0.000000000000000000001891 109.0
CMS2_k127_1878113_35 type II secretion system protein K K02460 - - 0.0000000000000000002024 100.0
CMS2_k127_1878113_36 Tetratricopeptide repeat - - - 0.00000000001516 77.0
CMS2_k127_1878113_37 Prokaryotic N-terminal methylation motif K02458 - - 0.000000000141 66.0
CMS2_k127_1878113_38 PFAM Integrase catalytic region - - - 0.000002056 54.0
CMS2_k127_1878113_39 - K02463 - - 0.000249 53.0
CMS2_k127_1878113_4 PFAM Type II secretion system protein E K02454 - - 8.858e-195 623.0
CMS2_k127_1878113_40 Subtilase family K14645 - - 0.0003696 50.0
CMS2_k127_1878113_5 COGs COG2303 Choline dehydrogenase and related flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 514.0
CMS2_k127_1878113_6 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 504.0
CMS2_k127_1878113_7 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 481.0
CMS2_k127_1878113_8 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 460.0
CMS2_k127_1878113_9 Type II secretion system K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005853 385.0
CMS2_k127_1959569_0 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K03520 - 1.2.5.3 0.0 1366.0
CMS2_k127_1959569_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 6.968e-257 802.0
CMS2_k127_1959569_10 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 300.0
CMS2_k127_1959569_11 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 288.0
CMS2_k127_1959569_12 beta-lactamase activity K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003177 285.0
CMS2_k127_1959569_13 Class II aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001172 268.0
CMS2_k127_1959569_14 Carbon monoxide dehydrogenase operon C protein K21696 GO:0006355,GO:0006808,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001127 261.0
CMS2_k127_1959569_15 transport system fused permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004176 254.0
CMS2_k127_1959569_16 helix_turn_helix, arabinose operon control protein K02508,K18954 - - 0.00000000000000000000000000000000000000000000000000000000000000001869 234.0
CMS2_k127_1959569_17 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000004079 230.0
CMS2_k127_1959569_18 Thioesterase superfamily K01075 - 3.1.2.23 0.000000000000000000000000000000000006578 140.0
CMS2_k127_1959569_19 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000002999 137.0
CMS2_k127_1959569_2 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 524.0
CMS2_k127_1959569_3 C4-dicarboxylate ABC transporter permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 525.0
CMS2_k127_1959569_4 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 524.0
CMS2_k127_1959569_5 methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 467.0
CMS2_k127_1959569_6 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 383.0
CMS2_k127_1959569_7 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 377.0
CMS2_k127_1959569_8 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 353.0
CMS2_k127_1959569_9 VWA domain containing CoxE-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007917 333.0
CMS2_k127_2096799_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01847 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 463.0
CMS2_k127_2096799_1 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 0.00000000000000000000000000000000000000000001337 163.0
CMS2_k127_2096799_3 - - - - 0.00000001083 67.0
CMS2_k127_2119352_0 Tripartite tricarboxylate transporter TctA family K07793 - - 9.256e-255 794.0
CMS2_k127_2119352_1 N-methylhydantoinase A acetone carboxylase, beta subunit - - - 1.401e-205 659.0
CMS2_k127_2119352_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 462.0
CMS2_k127_2119352_11 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 423.0
CMS2_k127_2119352_12 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 409.0
CMS2_k127_2119352_13 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 406.0
CMS2_k127_2119352_14 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003958 402.0
CMS2_k127_2119352_15 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 385.0
CMS2_k127_2119352_16 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 368.0
CMS2_k127_2119352_17 COG1840 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 371.0
CMS2_k127_2119352_18 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 291.0
CMS2_k127_2119352_19 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001576 277.0
CMS2_k127_2119352_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.392e-201 634.0
CMS2_k127_2119352_20 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001506 273.0
CMS2_k127_2119352_21 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000001059 175.0
CMS2_k127_2119352_22 OsmC-like protein - - - 0.00000000000000000000000000000000000000001146 158.0
CMS2_k127_2119352_23 PFAM extracellular solute-binding protein family 1 K02020,K22003 - 5.3.3.7 0.0000000000000000000003861 105.0
CMS2_k127_2119352_3 Tripartite tricarboxylate transporter TctA family - - - 1.935e-199 632.0
CMS2_k127_2119352_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.152e-197 619.0
CMS2_k127_2119352_5 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 545.0
CMS2_k127_2119352_6 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 504.0
CMS2_k127_2119352_7 Required for the activity of the bacterial periplasmic transport system of putrescine K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 480.0
CMS2_k127_2119352_8 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 469.0
CMS2_k127_2119352_9 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 461.0
CMS2_k127_2179543_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 1.573e-291 907.0
CMS2_k127_2179543_1 4Fe-4S dicluster domain - - - 5.038e-267 831.0
CMS2_k127_2179543_10 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 348.0
CMS2_k127_2179543_11 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 342.0
CMS2_k127_2179543_12 L,D-transpeptidase catalytic domain K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 314.0
CMS2_k127_2179543_13 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 299.0
CMS2_k127_2179543_14 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 296.0
CMS2_k127_2179543_15 Ribosomal protein S5, C-terminal domain K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001365 272.0
CMS2_k127_2179543_16 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000001368 242.0
CMS2_k127_2179543_17 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000005223 241.0
CMS2_k127_2179543_18 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000007426 224.0
CMS2_k127_2179543_19 structural constituent of ribosome K02879 - - 0.000000000000000000000000000000000000000000000000000000000002086 211.0
CMS2_k127_2179543_2 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 2.364e-224 701.0
CMS2_k127_2179543_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000125 208.0
CMS2_k127_2179543_21 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001916 209.0
CMS2_k127_2179543_22 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000000474 203.0
CMS2_k127_2179543_23 TIGRFAM sulfur relay protein TusD DsrE K07235 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0019417,GO:0044237,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000005638 203.0
CMS2_k127_2179543_24 Cell Wall Hydrolase - - - 0.0000000000000000000000000000000000000000000000000004759 190.0
CMS2_k127_2179543_25 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000000001944 185.0
CMS2_k127_2179543_26 Sulfur relay protein TusC DsrF K07236 - - 0.00000000000000000000000000000000000000000000000004424 184.0
CMS2_k127_2179543_27 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000001219 168.0
CMS2_k127_2179543_28 sulfur relay protein TusB DsrH K07237 - - 0.0000000000000000000000000000000001294 134.0
CMS2_k127_2179543_29 - - - - 0.000000000000000000000000000000003941 132.0
CMS2_k127_2179543_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.16e-220 691.0
CMS2_k127_2179543_30 Ribosomal protein L30 K02907 - - 0.000000000000000000005684 95.0
CMS2_k127_2179543_4 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 588.0
CMS2_k127_2179543_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 571.0
CMS2_k127_2179543_6 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 574.0
CMS2_k127_2179543_7 Belongs to the peptidase S1C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 546.0
CMS2_k127_2179543_8 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 513.0
CMS2_k127_2179543_9 Glycosyl transferase family, a/b domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 395.0
CMS2_k127_2197107_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 591.0
CMS2_k127_2197107_1 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001252 263.0
CMS2_k127_2197107_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000005312 127.0
CMS2_k127_2197107_3 Protein of unknown function (FYDLN_acid) - - - 0.00000000000000000001591 96.0
CMS2_k127_2197107_4 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000000000000001418 89.0
CMS2_k127_2242302_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1274.0
CMS2_k127_2242302_1 AMP-binding enzyme C-terminal domain K00666 - - 8.541e-279 865.0
CMS2_k127_2242302_10 Quinohemoprotein amine dehydrogenase - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000000000000000000000001535 173.0
CMS2_k127_2242302_11 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000443 149.0
CMS2_k127_2242302_12 S53 subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000000005659 149.0
CMS2_k127_2242302_13 Protein of unknown function (DUF2497) K09991 - - 0.000000000000000000002128 103.0
CMS2_k127_2242302_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 650.0
CMS2_k127_2242302_3 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 589.0
CMS2_k127_2242302_4 ABC transporter transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 541.0
CMS2_k127_2242302_5 COG1138 Cytochrome c biogenesis factor K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 484.0
CMS2_k127_2242302_6 Quinohemoprotein amine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 413.0
CMS2_k127_2242302_7 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 383.0
CMS2_k127_2242302_8 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 296.0
CMS2_k127_2242302_9 COG2518 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000001415 213.0
CMS2_k127_224537_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 516.0
CMS2_k127_224537_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 457.0
CMS2_k127_224537_2 glutamine amidotransferase K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 397.0
CMS2_k127_224537_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 377.0
CMS2_k127_2336386_0 Rieske [2Fe-2S] domain - - - 3.217e-214 672.0
CMS2_k127_2336386_1 TRAP transporter, 4TM 12TM fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 612.0
CMS2_k127_2336386_10 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000003846 234.0
CMS2_k127_2336386_11 peptidase m48, ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000001447 235.0
CMS2_k127_2336386_12 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000000001651 178.0
CMS2_k127_2336386_13 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000002747 158.0
CMS2_k127_2336386_14 ROS/MUCR transcriptional regulator protein - - - 0.000000000000000000000000000001788 125.0
CMS2_k127_2336386_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 489.0
CMS2_k127_2336386_3 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 387.0
CMS2_k127_2336386_4 oxidoreductase FAD NAD(P)-binding domain protein K18069,K21607 - 1.1.1.404 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 378.0
CMS2_k127_2336386_5 Peptidase M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 297.0
CMS2_k127_2336386_6 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 294.0
CMS2_k127_2336386_7 class II Aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 290.0
CMS2_k127_2336386_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000007572 241.0
CMS2_k127_2336386_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001016 231.0
CMS2_k127_236268_0 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 4.335e-212 665.0
CMS2_k127_236268_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009798 283.0
CMS2_k127_236268_2 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000004056 194.0
CMS2_k127_236268_3 Major facilitator superfamily - - - 0.0000000000000000000000000000000000009765 145.0
CMS2_k127_2373612_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916 - 6.3.1.5 1.556e-250 783.0
CMS2_k127_2373612_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 1.731e-210 664.0
CMS2_k127_2373612_10 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000004776 123.0
CMS2_k127_2373612_11 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000157 117.0
CMS2_k127_2373612_12 LemA family K03744 - - 0.000000008558 64.0
CMS2_k127_2373612_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 576.0
CMS2_k127_2373612_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 566.0
CMS2_k127_2373612_4 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 518.0
CMS2_k127_2373612_5 DoxX-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 366.0
CMS2_k127_2373612_6 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000000000004558 213.0
CMS2_k127_2373612_7 Predicted integral membrane protein (DUF2269) - - - 0.00000000000000000000000000000000000000000000000000002221 194.0
CMS2_k127_2373612_8 - - - - 0.0000000000000000000000000000000003128 142.0
CMS2_k127_2373612_9 - - - - 0.000000000000000000000000000000001683 141.0
CMS2_k127_242324_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 391.0
CMS2_k127_242324_1 COG0616 Periplasmic serine proteases (ClpP class) K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 352.0
CMS2_k127_2428458_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0 1343.0
CMS2_k127_2428458_1 Phosphopantetheine attachment site - - - 4.256e-289 915.0
CMS2_k127_2428458_10 Belongs to the HpcH HpaI aldolase family K08691 - 4.1.3.24,4.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 525.0
CMS2_k127_2428458_11 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 505.0
CMS2_k127_2428458_12 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 472.0
CMS2_k127_2428458_13 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 450.0
CMS2_k127_2428458_14 Domain of unknown function DUF108 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 374.0
CMS2_k127_2428458_15 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 360.0
CMS2_k127_2428458_16 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 357.0
CMS2_k127_2428458_17 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 350.0
CMS2_k127_2428458_18 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 338.0
CMS2_k127_2428458_19 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001812 280.0
CMS2_k127_2428458_2 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component K11690 GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0044425 - 4.411e-233 727.0
CMS2_k127_2428458_20 TRAP-type C4-dicarboxylate transport system, small permease component K11689 GO:0003674,GO:0005215,GO:0005310,GO:0005342,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015318,GO:0015556,GO:0015711,GO:0015740,GO:0015849,GO:0022857,GO:0034220,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000003713 247.0
CMS2_k127_2428458_21 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000000000008582 233.0
CMS2_k127_2428458_22 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000003908 223.0
CMS2_k127_2428458_23 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000004118 196.0
CMS2_k127_2428458_24 - - - - 0.000000000000000000000000000000000000000000000000004141 202.0
CMS2_k127_2428458_25 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000001988 201.0
CMS2_k127_2428458_27 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000001373 135.0
CMS2_k127_2428458_28 Mg2 and Co2 transporter CorB - - - 0.000000000000000000000000000000007261 131.0
CMS2_k127_2428458_3 COG2873 O-acetylhomoserine sulfhydrylase - - - 2.079e-215 674.0
CMS2_k127_2428458_30 Acetyltransferase (GNAT) domain - - - 0.000000005518 64.0
CMS2_k127_2428458_4 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 9.91e-212 668.0
CMS2_k127_2428458_5 Tripartite tricarboxylate transporter TctA family K07793 - - 3.157e-207 659.0
CMS2_k127_2428458_6 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 584.0
CMS2_k127_2428458_7 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 579.0
CMS2_k127_2428458_8 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 562.0
CMS2_k127_2428458_9 cytosine transport K03457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009303 540.0
CMS2_k127_2457006_0 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.0 1112.0
CMS2_k127_2457006_1 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0 1047.0
CMS2_k127_2457006_10 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 364.0
CMS2_k127_2457006_11 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 302.0
CMS2_k127_2457006_12 Acyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 282.0
CMS2_k127_2457006_13 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003175 281.0
CMS2_k127_2457006_14 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000006728 241.0
CMS2_k127_2457006_15 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000001063 236.0
CMS2_k127_2457006_16 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000004573 216.0
CMS2_k127_2457006_17 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000003618 171.0
CMS2_k127_2457006_18 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000008838 149.0
CMS2_k127_2457006_19 transport system, small permease component - - - 0.00000000000000000000000000000000002445 141.0
CMS2_k127_2457006_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 5.338e-286 886.0
CMS2_k127_2457006_20 Pfam:DUF1049 - - - 0.0000000000000008016 81.0
CMS2_k127_2457006_21 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000602 57.0
CMS2_k127_2457006_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.232e-222 695.0
CMS2_k127_2457006_4 Tripartite ATP-independent periplasmic transporter, DctM component K11690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 561.0
CMS2_k127_2457006_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 460.0
CMS2_k127_2457006_6 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 466.0
CMS2_k127_2457006_7 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 437.0
CMS2_k127_2457006_8 phosphatidate Cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 410.0
CMS2_k127_2457006_9 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 392.0
CMS2_k127_247136_0 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 539.0
CMS2_k127_247136_1 Dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 475.0
CMS2_k127_247136_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 411.0
CMS2_k127_247136_3 DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 315.0
CMS2_k127_247136_4 Non-motile and phage-resistance protein K07716 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000001866 228.0
CMS2_k127_247136_5 Cold shock protein domain K03704 - - 0.00000000000000000000000000002205 119.0
CMS2_k127_247136_6 - - - - 0.000000000000000001561 85.0
CMS2_k127_247136_7 - - - - 0.0000000000005436 79.0
CMS2_k127_247136_8 Cytochrome c - - - 0.0000000004339 66.0
CMS2_k127_2472543_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812,K08351 - 1.7.2.3 2.37e-246 770.0
CMS2_k127_2472543_1 Aminotransferase class-V K00830,K03430 - 2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004673 443.0
CMS2_k127_2472543_10 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000002197 103.0
CMS2_k127_2472543_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 438.0
CMS2_k127_2472543_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 357.0
CMS2_k127_2472543_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000334 245.0
CMS2_k127_2472543_5 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000499 265.0
CMS2_k127_2472543_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000001371 244.0
CMS2_k127_2472543_7 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000001745 236.0
CMS2_k127_2472543_8 COQ9 K18587 - - 0.00000000000000000000000000000000000000000000000000000000000009663 219.0
CMS2_k127_2472543_9 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000004217 171.0
CMS2_k127_2483548_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 522.0
CMS2_k127_2483548_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 316.0
CMS2_k127_2483548_2 Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone K03880 - 1.6.5.3 0.000000000000000000000000000000000000000000000000007531 183.0
CMS2_k127_2489873_0 Vault protein inter-alpha-trypsin domain K07114 - - 5.924e-231 734.0
CMS2_k127_2489873_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.898e-225 706.0
CMS2_k127_2489873_10 Phytoene synthase K21678 - 2.5.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002064 278.0
CMS2_k127_2489873_11 Squalene/phytoene synthase K21678,K21679 - 2.5.1.103,4.2.3.156 0.000000000000000000000000000000000000000000000000000000000000000000000000000001685 292.0
CMS2_k127_2489873_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000001657 248.0
CMS2_k127_2489873_13 NnrU protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006206 230.0
CMS2_k127_2489873_14 Belongs to the peptidase S8 family K12685 - - 0.0000000000000000000000000000000000000000000000000000000000001932 238.0
CMS2_k127_2489873_15 - - - - 0.00000000000000000000000000000000000000000000767 173.0
CMS2_k127_2489873_16 NnrU protein - - - 0.0000000000000000000000000000000000001947 153.0
CMS2_k127_2489873_17 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000000000004665 116.0
CMS2_k127_2489873_18 Gram-negative porin K08720 - - 0.000000000000000000000000001254 126.0
CMS2_k127_2489873_19 - - - - 0.00000000000000000000000546 113.0
CMS2_k127_2489873_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 631.0
CMS2_k127_2489873_20 Nacht domain - - - 0.0000000000000000000235 100.0
CMS2_k127_2489873_21 YGGT family K02221 - - 0.0000000000000000003871 93.0
CMS2_k127_2489873_22 Belongs to the 'phage' integrase family - - - 0.000000000000000008826 91.0
CMS2_k127_2489873_23 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000001749 75.0
CMS2_k127_2489873_24 Chorismate mutase K00014,K00891,K04092,K04516 - 1.1.1.25,2.7.1.71,5.4.99.5 0.00001975 47.0
CMS2_k127_2489873_25 Chorismate mutase K00014,K00891,K04092,K04516 - 1.1.1.25,2.7.1.71,5.4.99.5 0.00002618 48.0
CMS2_k127_2489873_3 Histidine kinase K07641,K07711 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031667,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009661 497.0
CMS2_k127_2489873_4 Surface antigen K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 475.0
CMS2_k127_2489873_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 442.0
CMS2_k127_2489873_6 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 377.0
CMS2_k127_2489873_7 Domain of unknown function (DUF4173) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 353.0
CMS2_k127_2489873_8 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 332.0
CMS2_k127_2489873_9 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 317.0
CMS2_k127_2492890_0 Tex-like protein N-terminal domain K06959 - - 0.0 1017.0
CMS2_k127_2492890_1 ATP-dependent helicase K03579 - 3.6.4.13 2.479e-301 945.0
CMS2_k127_2492890_10 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000001503 83.0
CMS2_k127_2492890_11 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.000005166 48.0
CMS2_k127_2492890_2 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 6.74e-211 666.0
CMS2_k127_2492890_3 L,D-transpeptidase catalytic domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 498.0
CMS2_k127_2492890_4 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 314.0
CMS2_k127_2492890_5 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000006938 226.0
CMS2_k127_2492890_6 COG0526 Thiol-disulfide isomerase and thioredoxins K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000001301 202.0
CMS2_k127_2492890_7 Haem-degrading - - - 0.0000000000000000000000000000000000000000000000009579 179.0
CMS2_k127_2492890_8 Belongs to the DsbB family K03611 - - 0.000000000000000000000000000000000000000000000006423 176.0
CMS2_k127_2492890_9 Protein of unknown function (DUF1294) - - - 0.000000000000000000000000000000000000006841 153.0
CMS2_k127_2509351_0 Bacterial NAD-glutamate dehydrogenase K15371 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 1.4.1.2 0.0 1795.0
CMS2_k127_2509351_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1341.0
CMS2_k127_2509351_10 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 6.012e-232 728.0
CMS2_k127_2509351_100 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.000000000000000000000000000000005806 130.0
CMS2_k127_2509351_101 Belongs to the UPF0145 family - - - 0.00000000000000000000000000000003097 130.0
CMS2_k127_2509351_102 COG1525 Micrococcal nuclease (thermonuclease) homologs - - - 0.0000000000000000000000000000005575 131.0
CMS2_k127_2509351_103 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000002568 123.0
CMS2_k127_2509351_104 - - - - 0.0000000000000000000000000000026 126.0
CMS2_k127_2509351_105 Belongs to the peptidase M50B family - - - 0.000000000000000000000001012 119.0
CMS2_k127_2509351_106 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.000000000000000000000005176 107.0
CMS2_k127_2509351_107 Belongs to the UPF0434 family K09791 - - 0.00000000000000000000001186 101.0
CMS2_k127_2509351_108 Lipopolysaccharide-assembly K03643 - - 0.00000000000000000000001531 107.0
CMS2_k127_2509351_109 Staphylococcal nuclease homologue - - - 0.000000000000000000004126 101.0
CMS2_k127_2509351_11 LUD domain K18929 - - 1.342e-216 683.0
CMS2_k127_2509351_111 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000002759 81.0
CMS2_k127_2509351_113 cyclic nucleotide binding K10914 - - 0.00000001003 67.0
CMS2_k127_2509351_114 - - - - 0.00000001245 58.0
CMS2_k127_2509351_116 antisigma factor binding K04749 - - 0.0001491 49.0
CMS2_k127_2509351_12 COG0004 Ammonia permease K03320 - - 5.611e-216 680.0
CMS2_k127_2509351_13 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.862e-213 673.0
CMS2_k127_2509351_14 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 586.0
CMS2_k127_2509351_15 COG0471 Di- and tricarboxylate transporters K03319,K09477,K11106,K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 586.0
CMS2_k127_2509351_16 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 542.0
CMS2_k127_2509351_17 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 522.0
CMS2_k127_2509351_18 Oxidative deamination of D-amino acids - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 512.0
CMS2_k127_2509351_19 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 499.0
CMS2_k127_2509351_2 ABC transporter transmembrane region K02021 - - 4.63e-289 913.0
CMS2_k127_2509351_20 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 489.0
CMS2_k127_2509351_21 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 483.0
CMS2_k127_2509351_22 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 501.0
CMS2_k127_2509351_23 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 490.0
CMS2_k127_2509351_24 ATPase with chaperone activity K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 469.0
CMS2_k127_2509351_25 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 477.0
CMS2_k127_2509351_26 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009333 467.0
CMS2_k127_2509351_27 Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 486.0
CMS2_k127_2509351_28 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 467.0
CMS2_k127_2509351_29 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 461.0
CMS2_k127_2509351_3 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 5.802e-277 868.0
CMS2_k127_2509351_30 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01907 - 6.2.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 457.0
CMS2_k127_2509351_31 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 450.0
CMS2_k127_2509351_32 COG0436 Aspartate tyrosine aromatic aminotransferase K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 439.0
CMS2_k127_2509351_33 Histidine biosynthesis protein K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 423.0
CMS2_k127_2509351_34 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 400.0
CMS2_k127_2509351_35 HemY protein N-terminus K02498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 399.0
CMS2_k127_2509351_36 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 393.0
CMS2_k127_2509351_37 membrane-bound lytic murein transglycosylase K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 389.0
CMS2_k127_2509351_38 Chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 372.0
CMS2_k127_2509351_39 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 365.0
CMS2_k127_2509351_4 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 9.608e-277 871.0
CMS2_k127_2509351_40 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 365.0
CMS2_k127_2509351_41 COG0708 Exonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 364.0
CMS2_k127_2509351_42 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 362.0
CMS2_k127_2509351_43 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 361.0
CMS2_k127_2509351_44 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 370.0
CMS2_k127_2509351_45 (Fe-S) oxidoreductase K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 350.0
CMS2_k127_2509351_46 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 357.0
CMS2_k127_2509351_47 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 344.0
CMS2_k127_2509351_48 Catalyzes the formation of 5-(5-phospho-1-deoxyribulos-1-ylamino)methylideneamino-l- (5-hosphoribosyl)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-5- (5- phosphoribosylamino)methylideneamino imidazole-4-carboxamide K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 340.0
CMS2_k127_2509351_49 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 345.0
CMS2_k127_2509351_5 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 3.025e-276 861.0
CMS2_k127_2509351_50 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 334.0
CMS2_k127_2509351_51 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 332.0
CMS2_k127_2509351_52 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 346.0
CMS2_k127_2509351_53 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 340.0
CMS2_k127_2509351_54 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 323.0
CMS2_k127_2509351_55 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 319.0
CMS2_k127_2509351_56 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 312.0
CMS2_k127_2509351_57 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 316.0
CMS2_k127_2509351_58 Cupin superfamily protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 319.0
CMS2_k127_2509351_59 AMP binding K09118,K13693 - 2.4.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 312.0
CMS2_k127_2509351_6 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 8.801e-275 860.0
CMS2_k127_2509351_60 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 310.0
CMS2_k127_2509351_61 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 321.0
CMS2_k127_2509351_62 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006304 301.0
CMS2_k127_2509351_63 Asp Glu Hydantoin racemase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 294.0
CMS2_k127_2509351_64 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 309.0
CMS2_k127_2509351_65 Alanine racemase, N-terminal domain K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 292.0
CMS2_k127_2509351_66 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 284.0
CMS2_k127_2509351_67 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002027 280.0
CMS2_k127_2509351_68 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001533 276.0
CMS2_k127_2509351_69 Pfam Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003696 269.0
CMS2_k127_2509351_7 FtsH Extracellular K03798 - - 2.418e-250 790.0
CMS2_k127_2509351_70 to the N-terminal domain of Lon protease K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000211 248.0
CMS2_k127_2509351_71 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001342 249.0
CMS2_k127_2509351_72 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000001539 242.0
CMS2_k127_2509351_73 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000002224 238.0
CMS2_k127_2509351_74 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000004986 231.0
CMS2_k127_2509351_75 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000001148 241.0
CMS2_k127_2509351_76 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000529 228.0
CMS2_k127_2509351_77 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000000000000000000000000000000000003259 226.0
CMS2_k127_2509351_78 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008855 231.0
CMS2_k127_2509351_79 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000007567 232.0
CMS2_k127_2509351_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 5.245e-249 782.0
CMS2_k127_2509351_80 COG1587 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000001827 218.0
CMS2_k127_2509351_81 - - - - 0.00000000000000000000000000000000000000000000000000000000004627 210.0
CMS2_k127_2509351_82 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000001412 211.0
CMS2_k127_2509351_83 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000004019 207.0
CMS2_k127_2509351_84 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000000000000007374 202.0
CMS2_k127_2509351_85 S-adenosyl-L-methionine methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000002274 204.0
CMS2_k127_2509351_86 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000005064 205.0
CMS2_k127_2509351_87 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000000000000000000001092 199.0
CMS2_k127_2509351_88 transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000031 213.0
CMS2_k127_2509351_89 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000000003484 195.0
CMS2_k127_2509351_9 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 5.391e-240 747.0
CMS2_k127_2509351_90 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000002884 194.0
CMS2_k127_2509351_91 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000004104 180.0
CMS2_k127_2509351_92 Domain of unknown function (DUF3576) - - - 0.00000000000000000000000000000000000000000000001675 177.0
CMS2_k127_2509351_93 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000001558 166.0
CMS2_k127_2509351_94 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000002318 169.0
CMS2_k127_2509351_95 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000003155 151.0
CMS2_k127_2509351_96 protein conserved in bacteria - - - 0.000000000000000000000000000000000000132 148.0
CMS2_k127_2509351_97 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000002746 142.0
CMS2_k127_2509351_98 COG3030 Protein affecting phage T7 exclusion by the F plasmid K07113 - - 0.000000000000000000000000000000000005604 142.0
CMS2_k127_2509351_99 Mitochondrial inner membrane protein - - - 0.000000000000000000000000000000000006326 154.0
CMS2_k127_2521126_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1042.0
CMS2_k127_2521126_1 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 1.52e-286 904.0
CMS2_k127_2521126_10 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 337.0
CMS2_k127_2521126_11 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 333.0
CMS2_k127_2521126_12 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 321.0
CMS2_k127_2521126_13 serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 305.0
CMS2_k127_2521126_14 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000005739 227.0
CMS2_k127_2521126_15 transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000000000000000000000001414 216.0
CMS2_k127_2521126_16 protein conserved in archaea - - - 0.0000000000000000000000000000000000000000000000004674 183.0
CMS2_k127_2521126_17 COG3143 Chemotaxis protein K03414 - - 0.000000000000000000000000000000000000001892 155.0
CMS2_k127_2521126_18 Transcriptional regulator - - - 0.0000000000000000000000000000000000001721 146.0
CMS2_k127_2521126_19 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000003516 142.0
CMS2_k127_2521126_2 FeS assembly protein SufB K09014 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009536,GO:0009842,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 - 7.583e-202 642.0
CMS2_k127_2521126_20 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000005955 136.0
CMS2_k127_2521126_21 - - - - 0.000000000000000000022 94.0
CMS2_k127_2521126_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 9.952e-195 614.0
CMS2_k127_2521126_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007152 523.0
CMS2_k127_2521126_5 Belongs to the RimK family K05844,K14940 - 6.3.2.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 506.0
CMS2_k127_2521126_6 PCRF K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 501.0
CMS2_k127_2521126_7 succinylglutamate desuccinylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 416.0
CMS2_k127_2521126_8 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 434.0
CMS2_k127_2521126_9 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 383.0
CMS2_k127_252795_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 2.095e-314 969.0
CMS2_k127_252795_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.892e-249 794.0
CMS2_k127_252795_10 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 439.0
CMS2_k127_252795_11 2-polyprenylphenol hydroxylase and related flavodoxin K15753,K15765 - 1.18.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 424.0
CMS2_k127_252795_12 Catalyzes the reduction of tatronate semialdehyde to D- glycerate K00020,K00042 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 369.0
CMS2_k127_252795_13 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 301.0
CMS2_k127_252795_14 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 290.0
CMS2_k127_252795_15 helix_turn_helix isocitrate lyase regulation K13641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004287 285.0
CMS2_k127_252795_16 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000002354 246.0
CMS2_k127_252795_17 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003024 231.0
CMS2_k127_252795_18 Predicted permease - - - 0.000000000000000000000000000000000000000000000000000000000000001349 227.0
CMS2_k127_252795_19 endoribonuclease L-PSP - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000001052 202.0
CMS2_k127_252795_2 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K15060 - - 4.456e-239 744.0
CMS2_k127_252795_20 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000002444 195.0
CMS2_k127_252795_21 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000002787 202.0
CMS2_k127_252795_22 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710,K14750,K15752 - - 0.0000000000000000000000000000000000000000007562 161.0
CMS2_k127_252795_23 - - - - 0.000000000000000000000000000003137 126.0
CMS2_k127_252795_24 - - - - 0.000000000000000000000000000248 119.0
CMS2_k127_252795_25 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000006384 89.0
CMS2_k127_252795_26 Tripartite tricarboxylate transporter TctA family - - - 0.0003029 50.0
CMS2_k127_252795_3 ethanolamine utilization protein K04019 GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - 7.936e-216 684.0
CMS2_k127_252795_5 - - - - 9.395e-203 653.0
CMS2_k127_252795_6 Thiamine pyrophosphate enzyme, central domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 599.0
CMS2_k127_252795_7 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 536.0
CMS2_k127_252795_8 ethanolamine utilization protein K04019 GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0030091,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009,GO:0071704,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 538.0
CMS2_k127_252795_9 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 529.0
CMS2_k127_2574005_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1071.0
CMS2_k127_2574005_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 4.621e-303 936.0
CMS2_k127_2574005_10 Sodium:sulfate symporter transmembrane region K03319,K09477,K11106,K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 520.0
CMS2_k127_2574005_11 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 510.0
CMS2_k127_2574005_12 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 497.0
CMS2_k127_2574005_13 Peptidase M16 inactive domain K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 486.0
CMS2_k127_2574005_14 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 478.0
CMS2_k127_2574005_15 HI0933-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 459.0
CMS2_k127_2574005_16 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 433.0
CMS2_k127_2574005_17 NADP-dependent oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 419.0
CMS2_k127_2574005_18 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 417.0
CMS2_k127_2574005_19 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 376.0
CMS2_k127_2574005_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 5.345e-255 799.0
CMS2_k127_2574005_20 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 379.0
CMS2_k127_2574005_21 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 368.0
CMS2_k127_2574005_22 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 362.0
CMS2_k127_2574005_23 methyl-accepting chemotaxis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 376.0
CMS2_k127_2574005_24 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 331.0
CMS2_k127_2574005_25 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 331.0
CMS2_k127_2574005_26 Transmembrane secretion effector K08217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 335.0
CMS2_k127_2574005_27 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 316.0
CMS2_k127_2574005_28 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 309.0
CMS2_k127_2574005_29 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 294.0
CMS2_k127_2574005_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K16886 - - 6.901e-244 774.0
CMS2_k127_2574005_30 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009824 287.0
CMS2_k127_2574005_31 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001693 286.0
CMS2_k127_2574005_32 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004039 284.0
CMS2_k127_2574005_33 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000089 244.0
CMS2_k127_2574005_34 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000004277 222.0
CMS2_k127_2574005_35 COGs COG0790 FOG TPR repeat SEL1 subfamily - - - 0.0000000000000000000000000000000000000000000000000000000009946 212.0
CMS2_k127_2574005_36 Protein of unknown function (DUF2953) - - - 0.000000000000000000000000000000000000000000000003249 179.0
CMS2_k127_2574005_37 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000009436 178.0
CMS2_k127_2574005_38 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000008724 180.0
CMS2_k127_2574005_39 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.00000000000000000000000000000000000000000001744 165.0
CMS2_k127_2574005_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 585.0
CMS2_k127_2574005_40 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000008524 157.0
CMS2_k127_2574005_41 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000004059 137.0
CMS2_k127_2574005_42 Protein of unknown function (DUF3035) - - - 0.00000000000000000003708 100.0
CMS2_k127_2574005_43 Protein of unknown function (DUF3012) - - - 0.00000000000009817 75.0
CMS2_k127_2574005_44 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.0000000000013 70.0
CMS2_k127_2574005_45 Potassium channel K21867 - - 0.00000000003729 71.0
CMS2_k127_2574005_46 - - - - 0.000000101 59.0
CMS2_k127_2574005_47 Pfam Hemerythrin HHE - - - 0.0000004459 59.0
CMS2_k127_2574005_5 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 585.0
CMS2_k127_2574005_6 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 532.0
CMS2_k127_2574005_7 sulfate assimilation K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007356 530.0
CMS2_k127_2574005_8 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 526.0
CMS2_k127_2574005_9 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 519.0
CMS2_k127_2577833_0 transport system, fused permease components - - - 0.0 1036.0
CMS2_k127_2577833_1 D-Lysine 5,6-aminomutase alpha subunit K17898 - 5.4.3.5 1.532e-317 992.0
CMS2_k127_2577833_10 of poly-gamma-glutamate biosynthesis (Capsule formation) K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 489.0
CMS2_k127_2577833_11 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 470.0
CMS2_k127_2577833_12 SPFH domain / Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 476.0
CMS2_k127_2577833_13 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 454.0
CMS2_k127_2577833_14 Including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 435.0
CMS2_k127_2577833_15 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 427.0
CMS2_k127_2577833_16 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 422.0
CMS2_k127_2577833_17 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 421.0
CMS2_k127_2577833_18 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 413.0
CMS2_k127_2577833_19 Alanine racemase, N-terminal domain K21898 - 5.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 409.0
CMS2_k127_2577833_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 6.008e-314 998.0
CMS2_k127_2577833_20 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 402.0
CMS2_k127_2577833_21 geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 367.0
CMS2_k127_2577833_22 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 371.0
CMS2_k127_2577833_23 TRAP transporter solute receptor TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 357.0
CMS2_k127_2577833_24 Zinc carboxypeptidase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 356.0
CMS2_k127_2577833_25 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 343.0
CMS2_k127_2577833_26 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 349.0
CMS2_k127_2577833_27 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 355.0
CMS2_k127_2577833_28 saccharopine dehydrogenase activity K03340 - 1.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 321.0
CMS2_k127_2577833_29 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 316.0
CMS2_k127_2577833_3 formate dehydrogenase (NAD+) activity K00123,K05299 - 1.17.1.10,1.17.1.9 6.659e-297 937.0
CMS2_k127_2577833_30 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 310.0
CMS2_k127_2577833_31 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008767 304.0
CMS2_k127_2577833_32 methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 298.0
CMS2_k127_2577833_33 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 297.0
CMS2_k127_2577833_34 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 302.0
CMS2_k127_2577833_35 Sulfatase-modifying factor enzyme 1 K20333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005309 290.0
CMS2_k127_2577833_36 Sulfate permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002744 296.0
CMS2_k127_2577833_37 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009218 274.0
CMS2_k127_2577833_38 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000032 268.0
CMS2_k127_2577833_39 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000323 275.0
CMS2_k127_2577833_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 6.539e-273 866.0
CMS2_k127_2577833_40 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003544 271.0
CMS2_k127_2577833_41 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002357 294.0
CMS2_k127_2577833_42 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007752 256.0
CMS2_k127_2577833_43 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004372 256.0
CMS2_k127_2577833_44 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005554 256.0
CMS2_k127_2577833_45 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007854 247.0
CMS2_k127_2577833_46 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000008055 245.0
CMS2_k127_2577833_47 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001482 246.0
CMS2_k127_2577833_48 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002491 243.0
CMS2_k127_2577833_49 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000000000000000004149 238.0
CMS2_k127_2577833_5 Radical SAM K01012 - 2.8.1.6 3.09e-219 685.0
CMS2_k127_2577833_50 Glycine cleavage H-protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000002955 226.0
CMS2_k127_2577833_51 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000007802 208.0
CMS2_k127_2577833_52 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000002235 214.0
CMS2_k127_2577833_53 FCD - - - 0.000000000000000000000000000000000000000000000000000000002366 207.0
CMS2_k127_2577833_54 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000001826 205.0
CMS2_k127_2577833_55 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000357 199.0
CMS2_k127_2577833_56 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000002093 168.0
CMS2_k127_2577833_57 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000000000006757 163.0
CMS2_k127_2577833_58 GYD domain - - - 0.00000000000000000000000000000000000000003382 154.0
CMS2_k127_2577833_59 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000002693 150.0
CMS2_k127_2577833_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 2.864e-201 636.0
CMS2_k127_2577833_60 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000003512 152.0
CMS2_k127_2577833_61 Phage integrase family - - - 0.0000000000000000000000000000000000009195 148.0
CMS2_k127_2577833_62 D-ornithine 4,5-aminomutase alpha-subunit K17899 - 5.4.3.5 0.0000000000000000000000000000000004583 135.0
CMS2_k127_2577833_63 Domain of unknown function DUF123 - - - 0.0000000000000000000000000000000004594 136.0
CMS2_k127_2577833_64 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000006757 136.0
CMS2_k127_2577833_65 - - - - 0.0000000000000000000000000003022 128.0
CMS2_k127_2577833_66 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000001132 110.0
CMS2_k127_2577833_67 - - - - 0.00000000000000000000000231 109.0
CMS2_k127_2577833_68 - K21399 GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 2.3.1.263 0.0000000000000000000001767 112.0
CMS2_k127_2577833_69 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000001196 103.0
CMS2_k127_2577833_7 beta subunit K21400 - 2.3.1.263 1.069e-197 628.0
CMS2_k127_2577833_70 Dodecin K09165 - - 0.000000000000000000001513 96.0
CMS2_k127_2577833_72 - - - - 0.000000000000000001655 91.0
CMS2_k127_2577833_73 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000805 80.0
CMS2_k127_2577833_74 - - - - 0.00000000000003642 84.0
CMS2_k127_2577833_76 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 0.00000004355 65.0
CMS2_k127_2577833_77 Protein of unknown function (DUF3775) - - - 0.0000002391 60.0
CMS2_k127_2577833_79 - - - - 0.0000009996 59.0
CMS2_k127_2577833_8 Radical SAM K09711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 555.0
CMS2_k127_2577833_80 - - - - 0.000002293 52.0
CMS2_k127_2577833_81 TIGRFAM formate dehydrogenase, alpha subunit K00336,K05299 - 1.17.1.10,1.6.5.3 0.000008911 52.0
CMS2_k127_2577833_82 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0001777 46.0
CMS2_k127_2577833_9 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 518.0
CMS2_k127_2651785_0 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 2.576e-247 775.0
CMS2_k127_2651785_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 441.0
CMS2_k127_2651785_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 399.0
CMS2_k127_2651785_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 303.0
CMS2_k127_2651785_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 288.0
CMS2_k127_2651785_5 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000003094 195.0
CMS2_k127_2651785_6 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000003888 184.0
CMS2_k127_2651785_7 Cephalosporin hydroxylase - - - 0.000000000000000000000000000000005962 134.0
CMS2_k127_2651785_8 hemimethylated DNA binding K11940 - - 0.000000000000000000002087 97.0
CMS2_k127_269001_0 Berberine and berberine like - - - 4.114e-222 696.0
CMS2_k127_269001_1 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 580.0
CMS2_k127_269001_2 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 550.0
CMS2_k127_269001_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 427.0
CMS2_k127_269001_4 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004178 302.0
CMS2_k127_269001_5 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000008115 134.0
CMS2_k127_2699848_0 Belongs to the GcvT family - - - 0.0 1162.0
CMS2_k127_2699848_1 Belongs to the GcvT family K00315 - 1.5.8.4 0.0 1073.0
CMS2_k127_2699848_10 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 328.0
CMS2_k127_2699848_11 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 306.0
CMS2_k127_2699848_12 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000282 287.0
CMS2_k127_2699848_13 of the double-stranded beta helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007347 256.0
CMS2_k127_2699848_14 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000005941 205.0
CMS2_k127_2699848_15 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000009402 183.0
CMS2_k127_2699848_16 proteolysis - - - 0.000000000000000000000000000000000000000000000008936 183.0
CMS2_k127_2699848_17 - - - - 0.00000000000000000000000000000000000001341 150.0
CMS2_k127_2699848_18 Phospholipid N-methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000007769 151.0
CMS2_k127_2699848_19 - - - - 0.000000000000000000000000000000000002215 142.0
CMS2_k127_2699848_2 Trimethylamine methyltransferase (MTTB) - - - 5.992e-215 680.0
CMS2_k127_2699848_20 Protein of unknown function (DUF1499) - - - 0.000000000000000000000001898 110.0
CMS2_k127_2699848_21 - - - - 0.00000000000000000001738 97.0
CMS2_k127_2699848_22 membrane K00389 - - 0.00000000000000001047 88.0
CMS2_k127_2699848_23 - - - - 0.0000000005743 66.0
CMS2_k127_2699848_24 Encoded by - - - 0.00004094 54.0
CMS2_k127_2699848_3 Oxidoreductase domain protein - - - 5.811e-204 647.0
CMS2_k127_2699848_4 Glutamine synthetase, catalytic domain K01949 - 6.3.4.12 3.386e-199 639.0
CMS2_k127_2699848_5 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 518.0
CMS2_k127_2699848_6 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 426.0
CMS2_k127_2699848_7 PFAM regulatory protein LysR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 378.0
CMS2_k127_2699848_8 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 346.0
CMS2_k127_2699848_9 Aminotransferase, class I K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 347.0
CMS2_k127_2728154_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.301e-313 975.0
CMS2_k127_2728154_1 Peptidase family M28 K02083 - 3.5.3.9 3.1e-210 660.0
CMS2_k127_2728154_2 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 315.0
CMS2_k127_2728154_3 Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 307.0
CMS2_k127_2728154_4 Metalloenzyme superfamily K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000002257 181.0
CMS2_k127_2728154_5 Flp pilus assembly protein, pilin Flp K02651 - - 0.000000002875 59.0
CMS2_k127_2754328_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1200.0
CMS2_k127_2754328_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000001218 92.0
CMS2_k127_2770394_0 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 571.0
CMS2_k127_2770394_1 CbiX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 494.0
CMS2_k127_2770394_2 SMP-30/Gluconolaconase/LRE-like region K13874 - 3.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 359.0
CMS2_k127_2770394_3 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 318.0
CMS2_k127_2770394_4 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000004536 141.0
CMS2_k127_2770394_5 - - - - 0.0008835 45.0
CMS2_k127_2804641_0 Domain of unknown function (DUF3362) - - - 0.0 1128.0
CMS2_k127_2804641_1 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 8.441e-194 613.0
CMS2_k127_2804641_10 BMC - - - 0.00000000000000000000000000000000000005834 143.0
CMS2_k127_2804641_11 sulfurtransferase K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.0000000000000000000000000000000000002502 154.0
CMS2_k127_2804641_12 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000005979 117.0
CMS2_k127_2804641_13 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000000000000002249 116.0
CMS2_k127_2804641_14 Histidine kinase K07711,K19694 - 2.7.13.3 0.0000000000002185 76.0
CMS2_k127_2804641_15 - - - - 0.00000003292 60.0
CMS2_k127_2804641_16 - - - - 0.0000002124 53.0
CMS2_k127_2804641_17 - - - - 0.000394 49.0
CMS2_k127_2804641_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 575.0
CMS2_k127_2804641_3 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 490.0
CMS2_k127_2804641_4 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 389.0
CMS2_k127_2804641_5 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004605 338.0
CMS2_k127_2804641_6 Protoporphyrinogen oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 316.0
CMS2_k127_2804641_7 Carbon dioxide concentrating mechanism carboxysome shell protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 301.0
CMS2_k127_2804641_9 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 304.0
CMS2_k127_2870188_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.0 1068.0
CMS2_k127_2870188_1 May be involved in the biosynthesis of molybdopterin K03638,K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 294.0
CMS2_k127_2870188_2 PspA/IM30 family K03969 - - 0.0000000000000000000000000000000000000000000002812 182.0
CMS2_k127_2870188_3 Protein of unknown function (DUF1449) - - - 0.000000000000000000000000000000000000001214 155.0
CMS2_k127_2870188_4 spore germination - - - 0.00000000000000000002356 96.0
CMS2_k127_2870188_5 - - - - 0.00000000000000000003594 97.0
CMS2_k127_2900047_0 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 3.811e-289 892.0
CMS2_k127_2900047_1 COG4770 Acetyl propionyl-CoA carboxylase, alpha subunit K01965 - 6.4.1.3 1.048e-285 891.0
CMS2_k127_2900047_10 - - - - 0.000000000000000000000000000176 115.0
CMS2_k127_2900047_11 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000000001133 105.0
CMS2_k127_2900047_12 - - - - 0.000000000000005388 78.0
CMS2_k127_2900047_13 oligosaccharyl transferase activity - - - 0.000000000000007254 88.0
CMS2_k127_2900047_14 2TM domain - - - 0.00000000003924 68.0
CMS2_k127_2900047_15 - - - - 0.00000004056 64.0
CMS2_k127_2900047_16 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000009365 57.0
CMS2_k127_2900047_2 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 512.0
CMS2_k127_2900047_3 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 354.0
CMS2_k127_2900047_4 Bacterial extracellular solute-binding protein K22003 - 5.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000008837 241.0
CMS2_k127_2900047_5 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000005646 228.0
CMS2_k127_2900047_6 MAPEG family - - - 0.0000000000000000000000000000000000000000000000000000000000000006289 222.0
CMS2_k127_2900047_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.00000000000000000000000000000000000000000000000000000005937 204.0
CMS2_k127_2900047_8 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000003099 177.0
CMS2_k127_2900047_9 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000005252 142.0
CMS2_k127_291014_0 Threonine synthase K01733 - 4.2.3.1 1.482e-202 640.0
CMS2_k127_291014_1 Thiol disulfide interchange protein K04084,K08344 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 612.0
CMS2_k127_291014_10 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 377.0
CMS2_k127_291014_11 ATP synthase A chain K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 350.0
CMS2_k127_291014_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000006112 250.0
CMS2_k127_291014_13 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000954 246.0
CMS2_k127_291014_14 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000002704 231.0
CMS2_k127_291014_15 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.000000000000000000000000000000000000000000000000000000000006066 213.0
CMS2_k127_291014_16 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000003622 192.0
CMS2_k127_291014_17 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000002093 173.0
CMS2_k127_291014_18 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000000000003574 180.0
CMS2_k127_291014_19 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000004348 165.0
CMS2_k127_291014_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 563.0
CMS2_k127_291014_20 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000000011 145.0
CMS2_k127_291014_21 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000933 141.0
CMS2_k127_291014_22 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00000000000000000000000000003179 121.0
CMS2_k127_291014_23 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000004181 117.0
CMS2_k127_291014_24 Sel1-like repeats. K07126 - - 0.000000000000000000000000001785 122.0
CMS2_k127_291014_25 - - - - 0.0000000000000000000001962 104.0
CMS2_k127_291014_3 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 560.0
CMS2_k127_291014_4 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 536.0
CMS2_k127_291014_5 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 478.0
CMS2_k127_291014_6 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 470.0
CMS2_k127_291014_7 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 464.0
CMS2_k127_291014_8 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 454.0
CMS2_k127_291014_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 417.0
CMS2_k127_2970729_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.494e-223 699.0
CMS2_k127_2970729_1 Acyl-CoA dehydrogenase, N-terminal domain K00252 - 1.3.8.6 3.445e-221 691.0
CMS2_k127_2970729_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 331.0
CMS2_k127_2970729_11 ChrR Cupin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 313.0
CMS2_k127_2970729_12 effector of murein hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 310.0
CMS2_k127_2970729_13 Riboflavin synthase alpha chain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000514 279.0
CMS2_k127_2970729_14 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000174 257.0
CMS2_k127_2970729_15 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002404 249.0
CMS2_k127_2970729_16 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000007024 201.0
CMS2_k127_2970729_17 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000001163 203.0
CMS2_k127_2970729_18 ROS/MUCR transcriptional regulator protein - - - 0.00000000000000000000000000000000000000000000000000006291 191.0
CMS2_k127_2970729_19 COG0698 Ribose 5-phosphate isomerase RpiB K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000007997 188.0
CMS2_k127_2970729_2 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 582.0
CMS2_k127_2970729_20 HPP family - - - 0.000000000000000000000000000000000000000000000212 172.0
CMS2_k127_2970729_21 effector of murein hydrolase LrgA K06518 - - 0.00000000000000000000000000000008603 128.0
CMS2_k127_2970729_22 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000006127 131.0
CMS2_k127_2970729_3 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 560.0
CMS2_k127_2970729_4 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 529.0
CMS2_k127_2970729_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 471.0
CMS2_k127_2970729_6 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006959 394.0
CMS2_k127_2970729_7 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 385.0
CMS2_k127_2970729_8 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 379.0
CMS2_k127_2970729_9 Enoyl-CoA hydratase/isomerase K01692,K05605 - 3.1.2.4,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 385.0
CMS2_k127_3057604_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1144.0
CMS2_k127_3057604_1 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 6.291e-281 878.0
CMS2_k127_3057604_10 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001276 276.0
CMS2_k127_3057604_11 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000242 252.0
CMS2_k127_3057604_12 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000002937 228.0
CMS2_k127_3057604_13 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000001757 220.0
CMS2_k127_3057604_14 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000002921 218.0
CMS2_k127_3057604_15 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000001485 186.0
CMS2_k127_3057604_16 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000358 171.0
CMS2_k127_3057604_17 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000001883 152.0
CMS2_k127_3057604_18 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000009032 153.0
CMS2_k127_3057604_19 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000005705 141.0
CMS2_k127_3057604_2 COG1180 Pyruvate-formate lyase-activating enzyme - - - 5.37e-229 719.0
CMS2_k127_3057604_20 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000000000138 114.0
CMS2_k127_3057604_21 involved in chromosome partitioning K03496 - - 0.000000000000000000001416 106.0
CMS2_k127_3057604_3 COG0044 Dihydroorotase and related cyclic amidohydrolases K01465 - 3.5.2.3 1.133e-201 636.0
CMS2_k127_3057604_4 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 548.0
CMS2_k127_3057604_5 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 473.0
CMS2_k127_3057604_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 379.0
CMS2_k127_3057604_7 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 319.0
CMS2_k127_3057604_8 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000371 287.0
CMS2_k127_3057604_9 Amino acid synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001359 273.0
CMS2_k127_309670_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 6.513e-274 850.0
CMS2_k127_309670_1 Aminotransferase class-V - - - 1.611e-220 715.0
CMS2_k127_309670_10 COG0564 Pseudouridylate synthases, 23S RNA-specific K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 316.0
CMS2_k127_309670_11 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005705 258.0
CMS2_k127_309670_12 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000155 246.0
CMS2_k127_309670_13 HNH endonuclease K07454 - - 0.000000000000000000000000000000000000000000000000000000007687 207.0
CMS2_k127_309670_14 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000003265 158.0
CMS2_k127_309670_15 Domain of unknown function (DUF4297) - - - 0.000000000000000000000000008488 123.0
CMS2_k127_309670_16 - - - - 0.00000000000000000002021 93.0
CMS2_k127_309670_18 ABC-type multidrug transport system ATPase and permease K02021 - - 0.00000000002473 76.0
CMS2_k127_309670_19 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0002336 53.0
CMS2_k127_309670_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 592.0
CMS2_k127_309670_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 508.0
CMS2_k127_309670_4 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 518.0
CMS2_k127_309670_5 COG0656 Aldo keto reductases, related to diketogulonate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 391.0
CMS2_k127_309670_6 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 366.0
CMS2_k127_309670_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 364.0
CMS2_k127_309670_8 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 325.0
CMS2_k127_309670_9 glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008813 331.0
CMS2_k127_3109011_0 FAD dependent oxidoreductase K19191 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006575,GO:0006576,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008480,GO:0009056,GO:0009063,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016491,GO:0016645,GO:0019695,GO:0019752,GO:0019842,GO:0031406,GO:0031974,GO:0033218,GO:0034641,GO:0035999,GO:0036094,GO:0042133,GO:0042135,GO:0042219,GO:0042402,GO:0042426,GO:0042558,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0046483,GO:0046653,GO:0046997,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0055114,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0072341,GO:0097159,GO:0097164,GO:1901052,GO:1901053,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.5.3.19 1.659e-304 940.0
CMS2_k127_3109011_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 502.0
CMS2_k127_3109011_2 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 436.0
CMS2_k127_3109011_3 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 393.0
CMS2_k127_3109011_4 Binding-protein-dependent transport system inner membrane component K15552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 357.0
CMS2_k127_3109011_5 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 358.0
CMS2_k127_3109011_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 299.0
CMS2_k127_3109011_7 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005936 259.0
CMS2_k127_3109011_8 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000009893 252.0
CMS2_k127_3109011_9 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000006872 164.0
CMS2_k127_316379_0 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 511.0
CMS2_k127_316379_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 385.0
CMS2_k127_316379_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 321.0
CMS2_k127_316379_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 288.0
CMS2_k127_316379_4 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000000009183 223.0
CMS2_k127_316379_5 Putative AphA-like transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000009774 198.0
CMS2_k127_3165165_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 7.545e-292 911.0
CMS2_k127_3165165_1 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 480.0
CMS2_k127_3165165_10 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000004632 254.0
CMS2_k127_3165165_11 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000003438 235.0
CMS2_k127_3165165_12 COG5387 Chaperone required for the assembly of the mitochondrial F1-ATPase - - - 0.000000000000000000000000000000000000000000000000000000000001827 218.0
CMS2_k127_3165165_13 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000001735 200.0
CMS2_k127_3165165_14 - - - - 0.000000000000000000000000000000000000000000000000000007464 202.0
CMS2_k127_3165165_15 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000004668 149.0
CMS2_k127_3165165_16 AAA domain - - - 0.0000000000000001436 82.0
CMS2_k127_3165165_17 - - - - 0.000000000007691 73.0
CMS2_k127_3165165_18 AAA domain - - - 0.000001277 57.0
CMS2_k127_3165165_19 protein conserved in bacteria K09927 - - 0.000001289 51.0
CMS2_k127_3165165_2 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 419.0
CMS2_k127_3165165_3 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 423.0
CMS2_k127_3165165_4 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 331.0
CMS2_k127_3165165_5 AsmA family K07289,K07290 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 329.0
CMS2_k127_3165165_6 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 306.0
CMS2_k127_3165165_7 protein involved in outer membrane biogenesis K07289,K07290 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 323.0
CMS2_k127_3165165_8 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 291.0
CMS2_k127_3165165_9 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002019 276.0
CMS2_k127_316703_0 aminopeptidase N K01256 - 3.4.11.2 0.0 1045.0
CMS2_k127_316703_1 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000002619 243.0
CMS2_k127_316703_2 Peptidase C39, bacteriocin processing K06992 - - 0.000000000000000000000000000000000000000001209 159.0
CMS2_k127_316703_3 PFAM Cupin 2 conserved barrel domain protein K21700 - - 0.0000000000000000000000000000001864 127.0
CMS2_k127_316703_4 Cytochrome c - - - 0.000000000000005292 79.0
CMS2_k127_316703_5 Staphylococcal nuclease homologues - - - 0.00000008147 61.0
CMS2_k127_3180846_0 COG1178 ABC-type Fe3 transport system, permease component K02011 - - 2.026e-197 630.0
CMS2_k127_3180846_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 603.0
CMS2_k127_3180846_2 Inosine-uridine preferring nucleoside hydrolase K01239 GO:0003674,GO:0003824,GO:0006139,GO:0006152,GO:0006213,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008477,GO:0008655,GO:0009056,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009164,GO:0009165,GO:0009435,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019357,GO:0019358,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0034356,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0043094,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0045437,GO:0046135,GO:0046483,GO:0046496,GO:0046497,GO:0046700,GO:0050263,GO:0051186,GO:0051188,GO:0055086,GO:0070635,GO:0070636,GO:0071704,GO:0072521,GO:0072523,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006703 388.0
CMS2_k127_3180846_3 COG1840 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 376.0
CMS2_k127_3180846_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 337.0
CMS2_k127_3180846_5 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001389 245.0
CMS2_k127_3180846_6 Uncharacterised protein family (UPF0262) - - - 0.000000000000000000000000000000000000000000000000000000000001176 220.0
CMS2_k127_3180846_7 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.000000000000000000000000000000000000000000000000000000000002642 211.0
CMS2_k127_3194179_0 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 518.0
CMS2_k127_3194179_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 464.0
CMS2_k127_3194179_10 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000002857 153.0
CMS2_k127_3194179_11 TOBE domain - - - 0.0000000000000000000000000000000005567 136.0
CMS2_k127_3194179_12 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000002728 87.0
CMS2_k127_3194179_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 467.0
CMS2_k127_3194179_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 400.0
CMS2_k127_3194179_4 Binding-protein-dependent transport system inner membrane component K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 403.0
CMS2_k127_3194179_5 TOBE domain K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 391.0
CMS2_k127_3194179_6 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 357.0
CMS2_k127_3194179_7 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 297.0
CMS2_k127_3194179_8 Peptidase C13 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 299.0
CMS2_k127_3194179_9 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000000000000000000000000001167 207.0
CMS2_k127_3341540_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1062.0
CMS2_k127_3341540_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0048037,GO:0050163,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 1.039e-293 908.0
CMS2_k127_3341540_10 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 402.0
CMS2_k127_3341540_11 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 392.0
CMS2_k127_3341540_12 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 391.0
CMS2_k127_3341540_13 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 373.0
CMS2_k127_3341540_14 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 367.0
CMS2_k127_3341540_15 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 359.0
CMS2_k127_3341540_16 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 362.0
CMS2_k127_3341540_17 PFAM Cation K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 367.0
CMS2_k127_3341540_18 Belongs to the DapA family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 345.0
CMS2_k127_3341540_19 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 329.0
CMS2_k127_3341540_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 7.794e-203 638.0
CMS2_k127_3341540_20 transcriptional regulator K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 326.0
CMS2_k127_3341540_21 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 317.0
CMS2_k127_3341540_22 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 311.0
CMS2_k127_3341540_23 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 304.0
CMS2_k127_3341540_24 hydrolase (HAD superfamily) K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 299.0
CMS2_k127_3341540_25 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 304.0
CMS2_k127_3341540_26 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001086 286.0
CMS2_k127_3341540_27 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001774 287.0
CMS2_k127_3341540_28 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003254 254.0
CMS2_k127_3341540_29 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000004624 248.0
CMS2_k127_3341540_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 585.0
CMS2_k127_3341540_30 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002812 249.0
CMS2_k127_3341540_31 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000000000000008365 224.0
CMS2_k127_3341540_32 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000811 211.0
CMS2_k127_3341540_33 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000000000000222 209.0
CMS2_k127_3341540_34 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000001964 192.0
CMS2_k127_3341540_35 Protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000000001173 186.0
CMS2_k127_3341540_36 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000000000000501 160.0
CMS2_k127_3341540_37 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000002136 130.0
CMS2_k127_3341540_38 Excinuclease ABC, C subunit K07461 - - 0.000000000000000000000000001352 117.0
CMS2_k127_3341540_39 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000001584 102.0
CMS2_k127_3341540_4 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 507.0
CMS2_k127_3341540_5 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 477.0
CMS2_k127_3341540_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 450.0
CMS2_k127_3341540_7 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 440.0
CMS2_k127_3341540_8 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 428.0
CMS2_k127_3341540_9 Ethanolamine utilisation - propanediol utilisation K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 423.0
CMS2_k127_3361883_0 Aminotransferase class-III K00819,K00821 - 2.6.1.11,2.6.1.13,2.6.1.17 6.96e-240 745.0
CMS2_k127_3361883_1 Aldehyde dehydrogenase family K13922 - 1.2.1.87 2.555e-212 670.0
CMS2_k127_3361883_2 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 462.0
CMS2_k127_3361883_3 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 451.0
CMS2_k127_3361883_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 371.0
CMS2_k127_3361883_5 BMC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 315.0
CMS2_k127_3361883_6 - - - - 0.00000000000000000004794 94.0
CMS2_k127_3361883_7 Binding-protein-dependent transport system inner membrane component - - - 0.000000002535 59.0
CMS2_k127_3382593_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 4.951e-231 728.0
CMS2_k127_3382593_1 III protein, CoA-transferase family K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 544.0
CMS2_k127_3382593_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000005696 269.0
CMS2_k127_3382593_3 AMP-binding enzyme K01897,K12508 - 6.2.1.3,6.2.1.34 0.0000004094 57.0
CMS2_k127_3382593_4 Evidence 5 No homology to any previously reported sequences - - - 0.000001395 51.0
CMS2_k127_3382593_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000009178 50.0
CMS2_k127_340637_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 1.111e-226 710.0
CMS2_k127_340637_1 COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 - 2.7.13.3 2.933e-223 715.0
CMS2_k127_340637_10 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 466.0
CMS2_k127_340637_11 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 459.0
CMS2_k127_340637_12 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 451.0
CMS2_k127_340637_13 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 420.0
CMS2_k127_340637_14 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 396.0
CMS2_k127_340637_15 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009975,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 392.0
CMS2_k127_340637_16 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 379.0
CMS2_k127_340637_17 Amino-transferase class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 351.0
CMS2_k127_340637_18 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 324.0
CMS2_k127_340637_19 L,D-transpeptidase catalytic domain K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 311.0
CMS2_k127_340637_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 7.459e-213 668.0
CMS2_k127_340637_20 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001177 265.0
CMS2_k127_340637_21 BON domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001752 268.0
CMS2_k127_340637_22 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001056 243.0
CMS2_k127_340637_23 HAD-superfamily hydrolase subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000009766 231.0
CMS2_k127_340637_24 COG2867 Oligoketide cyclase lipid transport protein K18588 - - 0.0000000000000000000000000000000000000000000000000000000000000005933 224.0
CMS2_k127_340637_25 tRNA modification K06968 - 2.1.1.186 0.000000000000000000000000000000000000000000000000000001766 196.0
CMS2_k127_340637_26 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000001975 179.0
CMS2_k127_340637_27 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000002161 179.0
CMS2_k127_340637_28 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000001214 162.0
CMS2_k127_340637_29 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000003811 145.0
CMS2_k127_340637_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 8.435e-210 663.0
CMS2_k127_340637_30 Septum formation initiator - - - 0.0000000000000000000003445 99.0
CMS2_k127_340637_31 - - - - 0.000000000000000000004727 94.0
CMS2_k127_340637_32 TRANSCRIPTIONal - - - 0.0000000003177 70.0
CMS2_k127_340637_4 Potassium transporter peripheral membrane component K03499 - - 7.436e-205 646.0
CMS2_k127_340637_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 542.0
CMS2_k127_340637_6 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 512.0
CMS2_k127_340637_7 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 520.0
CMS2_k127_340637_8 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 479.0
CMS2_k127_340637_9 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 458.0
CMS2_k127_341464_0 Dehydratase large subunit - - - 0.0 1184.0
CMS2_k127_341464_1 Required for the activity of the bacterial periplasmic transport system of putrescine K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 491.0
CMS2_k127_341464_2 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007235 370.0
CMS2_k127_341464_3 Dehydratase small subunit - - - 0.00000000000000000000000000000000000000000001308 169.0
CMS2_k127_341464_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.00000000006166 65.0
CMS2_k127_3434852_0 TonB-dependent receptor, beta-barrel - - - 2.241e-252 818.0
CMS2_k127_3434852_1 Belongs to the amidase family - - - 5.387e-230 728.0
CMS2_k127_3434852_10 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 359.0
CMS2_k127_3434852_11 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 302.0
CMS2_k127_3434852_12 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006537 283.0
CMS2_k127_3434852_13 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000745 202.0
CMS2_k127_3434852_14 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000002886 173.0
CMS2_k127_3434852_15 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000008832 166.0
CMS2_k127_3434852_16 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000002024 174.0
CMS2_k127_3434852_18 Sulfurtransferase TusA - - - 0.000000000000000000000000000002299 121.0
CMS2_k127_3434852_2 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 5.616e-201 631.0
CMS2_k127_3434852_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 516.0
CMS2_k127_3434852_4 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 484.0
CMS2_k127_3434852_5 Required for the activity of the bacterial periplasmic transport system of putrescine K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 452.0
CMS2_k127_3434852_6 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 443.0
CMS2_k127_3434852_7 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 426.0
CMS2_k127_3434852_8 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008627 408.0
CMS2_k127_3434852_9 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 421.0
CMS2_k127_3485090_0 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 497.0
CMS2_k127_3485090_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 482.0
CMS2_k127_3485090_10 - - - - 0.000000000000000000000000000000001445 135.0
CMS2_k127_3485090_11 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000000002711 134.0
CMS2_k127_3485090_12 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000004667 70.0
CMS2_k127_3485090_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 482.0
CMS2_k127_3485090_3 ATPase with chaperone activity K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 396.0
CMS2_k127_3485090_4 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 361.0
CMS2_k127_3485090_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009774 360.0
CMS2_k127_3485090_6 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 342.0
CMS2_k127_3485090_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 290.0
CMS2_k127_3485090_8 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005879 266.0
CMS2_k127_3485090_9 periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000000000000000962 175.0
CMS2_k127_3508826_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1282.0
CMS2_k127_3508826_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.289e-295 919.0
CMS2_k127_3508826_10 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 474.0
CMS2_k127_3508826_11 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 451.0
CMS2_k127_3508826_12 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 429.0
CMS2_k127_3508826_13 NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 419.0
CMS2_k127_3508826_14 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 415.0
CMS2_k127_3508826_15 Protein conserved in bacteria K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 390.0
CMS2_k127_3508826_16 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 379.0
CMS2_k127_3508826_17 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 357.0
CMS2_k127_3508826_18 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 329.0
CMS2_k127_3508826_19 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 330.0
CMS2_k127_3508826_2 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 3.461e-275 870.0
CMS2_k127_3508826_20 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 328.0
CMS2_k127_3508826_21 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 316.0
CMS2_k127_3508826_22 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 304.0
CMS2_k127_3508826_23 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 297.0
CMS2_k127_3508826_24 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 292.0
CMS2_k127_3508826_25 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001494 285.0
CMS2_k127_3508826_26 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000187 282.0
CMS2_k127_3508826_27 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002832 276.0
CMS2_k127_3508826_28 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003244 278.0
CMS2_k127_3508826_29 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006234 274.0
CMS2_k127_3508826_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 3.042e-199 628.0
CMS2_k127_3508826_30 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001966 282.0
CMS2_k127_3508826_31 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002681 239.0
CMS2_k127_3508826_32 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000002892 238.0
CMS2_k127_3508826_33 pfam nudix K03574 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000001305 222.0
CMS2_k127_3508826_34 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000002181 231.0
CMS2_k127_3508826_35 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000008881 200.0
CMS2_k127_3508826_36 PFAM Methyltransferase type - - - 0.00000000000000000000000000000000000000000000000000003835 193.0
CMS2_k127_3508826_37 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000007917 186.0
CMS2_k127_3508826_38 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000000000000000000001181 184.0
CMS2_k127_3508826_39 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000000000000000000000000004538 178.0
CMS2_k127_3508826_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 3.43e-196 617.0
CMS2_k127_3508826_40 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000001054 121.0
CMS2_k127_3508826_41 Domain of unknown function (DUF4167) - - - 0.0000000000000000000000000001951 123.0
CMS2_k127_3508826_42 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000002416 115.0
CMS2_k127_3508826_43 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000005303 121.0
CMS2_k127_3508826_44 formate dehydrogenase (NAD+) activity - - - 0.0000000000000000000000001707 111.0
CMS2_k127_3508826_45 - - - - 0.000000000000000002246 98.0
CMS2_k127_3508826_46 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000004017 85.0
CMS2_k127_3508826_47 - - - - 0.000001358 55.0
CMS2_k127_3508826_48 - - - - 0.00001178 57.0
CMS2_k127_3508826_5 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 582.0
CMS2_k127_3508826_6 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 544.0
CMS2_k127_3508826_7 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 518.0
CMS2_k127_3508826_8 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 484.0
CMS2_k127_3508826_9 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 472.0
CMS2_k127_3669590_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1067.0
CMS2_k127_3669590_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1066.0
CMS2_k127_3669590_10 NADH-ubiquinone oxidoreductase chain 49kDa - - - 1.298e-210 667.0
CMS2_k127_3669590_100 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000000558 131.0
CMS2_k127_3669590_101 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00000000000000000000000000000573 124.0
CMS2_k127_3669590_102 Cbs domain - - - 0.0000000000000000000000000005924 119.0
CMS2_k127_3669590_103 Phasin protein - - - 0.00000000000000000000000001964 114.0
CMS2_k127_3669590_104 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000000000234 110.0
CMS2_k127_3669590_105 Membrane fusogenic activity K09806 - - 0.0000000000000000000000001655 108.0
CMS2_k127_3669590_106 serine-type aminopeptidase activity K14475 - - 0.000000000000000000001347 101.0
CMS2_k127_3669590_107 - - - - 0.000000000000000000002809 104.0
CMS2_k127_3669590_108 - - - - 0.0000000000000000003175 94.0
CMS2_k127_3669590_109 Sulfate permease family K03321 - - 0.00000000000000001051 87.0
CMS2_k127_3669590_11 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 8.455e-202 635.0
CMS2_k127_3669590_111 RNA repair, ligase-Pnkp-associating, region of Hen1 - - - 0.0000000000000002168 81.0
CMS2_k127_3669590_112 Protoglobin - - - 0.00000000003763 69.0
CMS2_k127_3669590_113 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000013 63.0
CMS2_k127_3669590_114 EF hand - - - 0.000000000493 66.0
CMS2_k127_3669590_115 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.000000008854 62.0
CMS2_k127_3669590_117 - - - - 0.00000004357 60.0
CMS2_k127_3669590_118 Heavy-metal resistance - - - 0.000001187 60.0
CMS2_k127_3669590_119 - - - - 0.000004244 53.0
CMS2_k127_3669590_12 AMP-binding enzyme C-terminal domain - - - 9.5e-199 634.0
CMS2_k127_3669590_120 - - - - 0.000007034 55.0
CMS2_k127_3669590_13 lysine 2,3-aminomutase - - - 9.567e-198 625.0
CMS2_k127_3669590_14 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 602.0
CMS2_k127_3669590_15 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 575.0
CMS2_k127_3669590_16 DNA methylase K13581 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 556.0
CMS2_k127_3669590_17 Protein of unknown function (DUF933) K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 544.0
CMS2_k127_3669590_18 COG0303 Molybdopterin biosynthesis enzyme K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 519.0
CMS2_k127_3669590_19 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 527.0
CMS2_k127_3669590_2 Aerotolerance regulator N-terminal - - - 6.505e-291 918.0
CMS2_k127_3669590_20 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 519.0
CMS2_k127_3669590_21 Glutathione S-transferase, C-terminal domain K07393 - 1.8.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 506.0
CMS2_k127_3669590_22 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 494.0
CMS2_k127_3669590_23 ABC-type Fe3 transport system, permease component K02063 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 500.0
CMS2_k127_3669590_24 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 486.0
CMS2_k127_3669590_25 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 - 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 479.0
CMS2_k127_3669590_26 mechanosensitive ion channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 501.0
CMS2_k127_3669590_27 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 470.0
CMS2_k127_3669590_28 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 475.0
CMS2_k127_3669590_29 Histidine kinase K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 470.0
CMS2_k127_3669590_3 Proton-conducting membrane transporter - - - 3.564e-286 893.0
CMS2_k127_3669590_30 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 484.0
CMS2_k127_3669590_31 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 462.0
CMS2_k127_3669590_32 COG1194 A G-specific DNA glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 457.0
CMS2_k127_3669590_33 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 447.0
CMS2_k127_3669590_34 ABC-type thiamine transport system, periplasmic component K02064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 463.0
CMS2_k127_3669590_35 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 444.0
CMS2_k127_3669590_36 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 451.0
CMS2_k127_3669590_37 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 465.0
CMS2_k127_3669590_38 poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 422.0
CMS2_k127_3669590_39 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 408.0
CMS2_k127_3669590_4 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.379e-284 891.0
CMS2_k127_3669590_40 D-ala D-ala ligase C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 404.0
CMS2_k127_3669590_41 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 373.0
CMS2_k127_3669590_42 transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 387.0
CMS2_k127_3669590_43 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 351.0
CMS2_k127_3669590_44 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 358.0
CMS2_k127_3669590_45 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 348.0
CMS2_k127_3669590_46 COG4237 Hydrogenase 4 membrane component (E) K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006059 335.0
CMS2_k127_3669590_47 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 332.0
CMS2_k127_3669590_48 Protein of unknown function (DUF1538) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 322.0
CMS2_k127_3669590_49 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 312.0
CMS2_k127_3669590_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 4.651e-264 827.0
CMS2_k127_3669590_50 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 314.0
CMS2_k127_3669590_51 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 304.0
CMS2_k127_3669590_52 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 286.0
CMS2_k127_3669590_53 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 288.0
CMS2_k127_3669590_54 Protein of unknown function (DUF1538) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 297.0
CMS2_k127_3669590_55 PFAM peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004443 287.0
CMS2_k127_3669590_56 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006312 286.0
CMS2_k127_3669590_57 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009125 275.0
CMS2_k127_3669590_58 Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system K02062 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001251 279.0
CMS2_k127_3669590_59 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001994 278.0
CMS2_k127_3669590_6 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 8.321e-260 821.0
CMS2_k127_3669590_60 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000227 280.0
CMS2_k127_3669590_61 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005008 272.0
CMS2_k127_3669590_62 Extradiol ring-cleavage dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000785 274.0
CMS2_k127_3669590_63 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001553 269.0
CMS2_k127_3669590_64 PFAM Response regulator receiver domain K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006778 264.0
CMS2_k127_3669590_65 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000003315 261.0
CMS2_k127_3669590_66 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001648 254.0
CMS2_k127_3669590_67 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000005304 261.0
CMS2_k127_3669590_68 PFAM Thiamin pyrophosphokinase catalytic K00949 - 2.7.6.2 0.00000000000000000000000000000000000000000000000000000000000000000000001471 248.0
CMS2_k127_3669590_69 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000113 252.0
CMS2_k127_3669590_7 membrane - - - 2.334e-252 799.0
CMS2_k127_3669590_70 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000001475 242.0
CMS2_k127_3669590_71 COG0314 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000019 235.0
CMS2_k127_3669590_72 Glycosyl transferase group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001698 236.0
CMS2_k127_3669590_73 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000004864 232.0
CMS2_k127_3669590_74 chitin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000008002 239.0
CMS2_k127_3669590_75 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002379 233.0
CMS2_k127_3669590_76 molybdopterin-guanine dinucleotide biosynthesis protein K03753 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000003159 228.0
CMS2_k127_3669590_77 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000383 218.0
CMS2_k127_3669590_78 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000004468 232.0
CMS2_k127_3669590_79 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000000000000000007178 219.0
CMS2_k127_3669590_8 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 1.835e-250 788.0
CMS2_k127_3669590_80 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000002639 213.0
CMS2_k127_3669590_81 Protein of unknown function (DUF1285) K09986 - - 0.00000000000000000000000000000000000000000000000000000000003377 210.0
CMS2_k127_3669590_82 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000006172 207.0
CMS2_k127_3669590_83 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000000000000000000142 199.0
CMS2_k127_3669590_84 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.0000000000000000000000000000000000000000000000000000002729 206.0
CMS2_k127_3669590_85 Putative bacterial sensory transduction regulator - - - 0.0000000000000000000000000000000000000000000000000000003409 199.0
CMS2_k127_3669590_86 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000005057 199.0
CMS2_k127_3669590_87 Putative tRNA binding domain K06878 - - 0.000000000000000000000000000000000000000000000000000005797 192.0
CMS2_k127_3669590_88 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000002753 198.0
CMS2_k127_3669590_89 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000007637 183.0
CMS2_k127_3669590_9 Proton-conducting membrane transporter K12141 - - 3.278e-244 764.0
CMS2_k127_3669590_90 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000002342 168.0
CMS2_k127_3669590_91 DoxX K15977 - - 0.00000000000000000000000000000000000000000002803 166.0
CMS2_k127_3669590_92 Pyroglutamyl peptidase K01304 - 3.4.19.3 0.000000000000000000000000000000000000000003361 169.0
CMS2_k127_3669590_93 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000001926 154.0
CMS2_k127_3669590_94 Protein of unknown function (DUF3775) - - - 0.0000000000000000000000000000000000000004659 152.0
CMS2_k127_3669590_95 transcriptional regulator - - - 0.00000000000000000000000000000000000001788 152.0
CMS2_k127_3669590_96 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000006375 152.0
CMS2_k127_3669590_97 Belongs to the P(II) protein family - - - 0.000000000000000000000000000000000001045 141.0
CMS2_k127_3669590_98 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000000000000002217 152.0
CMS2_k127_3669590_99 Helix-turn-helix - - - 0.0000000000000000000000000000000001969 135.0
CMS2_k127_3673127_0 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 475.0
CMS2_k127_3694940_0 aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 419.0
CMS2_k127_3694940_1 Transcriptional regulator K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 333.0
CMS2_k127_3694940_2 Trap-type c4-dicarboxylate transport system, periplasmic component - - - 0.000000000000005388 78.0
CMS2_k127_3707332_0 COG2873 O-acetylhomoserine sulfhydrylase K01738,K01740 - 2.5.1.47,2.5.1.49 6.568e-206 655.0
CMS2_k127_3707332_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 489.0
CMS2_k127_3707332_10 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000000002718 221.0
CMS2_k127_3707332_11 Di-haem oxidoreductase, putative peroxidase - - - 0.00000000000000000000000000000000000000000000000007732 188.0
CMS2_k127_3707332_12 Histidine Phosphotransfer domain - - - 0.0000000000000000000000000000000000000000000000007215 188.0
CMS2_k127_3707332_13 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000000000000001739 166.0
CMS2_k127_3707332_14 Thioesterase superfamily - - - 0.00000000000000000000000000000000000002711 148.0
CMS2_k127_3707332_15 Major Facilitator Superfamily - - - 0.000000000000000000000002898 106.0
CMS2_k127_3707332_16 Barstar (barnase inhibitor) - - - 0.00000000000000000000001987 105.0
CMS2_k127_3707332_17 Large exoproteins involved in heme utilization or adhesion K15125 - - 0.0000000000000001089 81.0
CMS2_k127_3707332_18 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.000000003156 57.0
CMS2_k127_3707332_19 silverDB - - - 0.0001563 52.0
CMS2_k127_3707332_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 335.0
CMS2_k127_3707332_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 326.0
CMS2_k127_3707332_4 COG3547 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 326.0
CMS2_k127_3707332_5 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 302.0
CMS2_k127_3707332_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001142 273.0
CMS2_k127_3707332_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005399 259.0
CMS2_k127_3707332_8 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000000003948 237.0
CMS2_k127_3707332_9 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000003651 231.0
CMS2_k127_3711887_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 5.418e-211 665.0
CMS2_k127_3711887_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 2.327e-198 627.0
CMS2_k127_3711887_10 Pilus assembly protein K02282 - - 0.00000000000000000000000000000000000000000000000000000000000001155 231.0
CMS2_k127_3711887_11 pilus assembly protein TadB K12510 - - 0.000000000000000000000000000000000000000000000000000000000009071 219.0
CMS2_k127_3711887_12 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000637 110.0
CMS2_k127_3711887_13 PFAM TadE family protein - - - 0.00000000000116 76.0
CMS2_k127_3711887_14 His Kinase A (phosphoacceptor) domain - - - 0.000000000005066 70.0
CMS2_k127_3711887_15 peptidyl-tyrosine sulfation - - - 0.0000006804 61.0
CMS2_k127_3711887_16 TIGRFAM pilus (Caulobacter type) biogenesis lipoprotein CpaD K02281 - - 0.000001102 59.0
CMS2_k127_3711887_17 TadE-like protein - - - 0.000006324 55.0
CMS2_k127_3711887_2 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 591.0
CMS2_k127_3711887_3 pilus assembly protein ATPase CpaF K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 573.0
CMS2_k127_3711887_4 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 521.0
CMS2_k127_3711887_5 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009445,GO:0009447,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0034024,GO:0034641,GO:0042402,GO:0044106,GO:0044237,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 462.0
CMS2_k127_3711887_6 FAD dependent oxidoreductase K09471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 426.0
CMS2_k127_3711887_7 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 356.0
CMS2_k127_3711887_8 type II secretion system protein K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003538 264.0
CMS2_k127_3711887_9 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000000000000007375 242.0
CMS2_k127_3744036_0 CobN/Magnesium Chelatase K02230 - 6.6.1.2 0.0 1705.0
CMS2_k127_3744036_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 3.638e-201 637.0
CMS2_k127_3744036_2 Cobalamin synthesis protein cobW C-terminal domain K02234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 469.0
CMS2_k127_3744036_3 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 319.0
CMS2_k127_3744036_4 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000658 172.0
CMS2_k127_3744036_5 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000003408 152.0
CMS2_k127_3744036_6 Domain of unknown function (DUF3520) K07114 - - 0.000000000000004737 76.0
CMS2_k127_3749612_0 Pyridoxal-phosphate dependent enzyme - - - 2.131e-203 645.0
CMS2_k127_3749612_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 385.0
CMS2_k127_3749612_2 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 346.0
CMS2_k127_3749612_3 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005373 274.0
CMS2_k127_3749612_4 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007973 272.0
CMS2_k127_3749612_5 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000003061 234.0
CMS2_k127_3749612_6 - - - - 0.0000000000000000000000000000000007966 142.0
CMS2_k127_3749612_8 Transposase K07483 - - 0.0005763 44.0
CMS2_k127_3783445_0 FAD dependent oxidoreductase central domain - - - 0.0 1013.0
CMS2_k127_3783445_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 4.074e-274 864.0
CMS2_k127_3783445_10 transport system, permease component K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 502.0
CMS2_k127_3783445_11 COBW domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 450.0
CMS2_k127_3783445_12 4,5-dihydroxyphthalate decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 417.0
CMS2_k127_3783445_13 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 401.0
CMS2_k127_3783445_14 Choline kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 376.0
CMS2_k127_3783445_15 PFAM class II aldolase adducin family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 365.0
CMS2_k127_3783445_16 D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 359.0
CMS2_k127_3783445_17 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 360.0
CMS2_k127_3783445_18 Aldolase/RraA K10218 GO:0003674,GO:0003824,GO:0006082,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0018918,GO:0018958,GO:0019336,GO:0019396,GO:0019439,GO:0019752,GO:0032787,GO:0042537,GO:0042737,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 4.1.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 349.0
CMS2_k127_3783445_19 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 370.0
CMS2_k127_3783445_2 COG4166 ABC-type oligopeptide transport system, periplasmic component K13893 - - 2.068e-248 780.0
CMS2_k127_3783445_20 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 352.0
CMS2_k127_3783445_21 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 340.0
CMS2_k127_3783445_22 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 288.0
CMS2_k127_3783445_23 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005329 249.0
CMS2_k127_3783445_24 phosphatase activity K07025,K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000001798 244.0
CMS2_k127_3783445_25 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000005532 226.0
CMS2_k127_3783445_26 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000001271 223.0
CMS2_k127_3783445_27 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000003599 183.0
CMS2_k127_3783445_28 COG1846 Transcriptional regulators - - - 0.00000000000000000000000000000000000001062 151.0
CMS2_k127_3783445_29 nitrate reductase molybdenum cofactor assembly chaperone - - - 0.0000000000000000000000000000000000002425 142.0
CMS2_k127_3783445_3 Belongs to the ABC transporter superfamily K13896 - - 1.287e-236 742.0
CMS2_k127_3783445_30 MAPEG family - - - 0.0000000000000000000000000003838 119.0
CMS2_k127_3783445_31 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000005895 87.0
CMS2_k127_3783445_32 Domain of unknown function (DUF1849) - - - 0.0000000000000119 84.0
CMS2_k127_3783445_33 Domain of unknown function (DUF1849) - - - 0.00000000000009709 83.0
CMS2_k127_3783445_35 Domain of unknown function (DUF1849) - - - 0.000000002808 68.0
CMS2_k127_3783445_36 Domain of unknown function (DUF1849) - - - 0.00000001329 67.0
CMS2_k127_3783445_37 DnaD domain protein - - - 0.00003188 47.0
CMS2_k127_3783445_38 DnaD domain protein - - - 0.00004781 50.0
CMS2_k127_3783445_4 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00008 - 1.1.1.14 1.333e-208 651.0
CMS2_k127_3783445_5 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 586.0
CMS2_k127_3783445_6 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 536.0
CMS2_k127_3783445_7 transport system, permease component K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 539.0
CMS2_k127_3783445_8 Putative methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007869 533.0
CMS2_k127_3783445_9 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 537.0
CMS2_k127_3789346_0 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009341 596.0
CMS2_k127_3789346_1 3-beta hydroxysteroid dehydrogenase/isomerase family K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 447.0
CMS2_k127_3789346_2 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000522 214.0
CMS2_k127_3789346_3 TPR repeat - - - 0.0000000000000000000000000000000000003823 145.0
CMS2_k127_3790080_0 Putative transposase - - - 1.096e-226 705.0
CMS2_k127_3790080_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 533.0
CMS2_k127_3790080_2 carboxymethylenebutenolidase activity K01061,K07017 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 285.0
CMS2_k127_3790080_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000756 82.0
CMS2_k127_3842634_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 1.287e-222 697.0
CMS2_k127_3842634_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 497.0
CMS2_k127_3842634_10 - - - - 0.0000000000000001449 83.0
CMS2_k127_3842634_11 Small protein - - - 0.00000004169 56.0
CMS2_k127_3842634_12 - - - - 0.000009605 52.0
CMS2_k127_3842634_2 transhydrogenase subunit alpha K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 487.0
CMS2_k127_3842634_3 Peptide ABC transporter substrate-binding protein K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 395.0
CMS2_k127_3842634_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 297.0
CMS2_k127_3842634_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812,K08351 - 1.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008606 290.0
CMS2_k127_3842634_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000003658 196.0
CMS2_k127_3842634_7 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000006188 166.0
CMS2_k127_3842634_8 Protein of unknown function (DUF2390) - - - 0.00000000000000000000171 105.0
CMS2_k127_3842634_9 Protein of unknown function (DUF465) - - - 0.0000000000000000007119 88.0
CMS2_k127_3852361_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0 1086.0
CMS2_k127_3852361_1 Bacterial extracellular solute-binding protein K17321 - - 0.0 1062.0
CMS2_k127_3852361_10 FAD binding domain K00103 - 1.1.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 482.0
CMS2_k127_3852361_11 Belongs to the ABC transporter superfamily K17324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 476.0
CMS2_k127_3852361_12 Binding-protein-dependent transport system inner membrane component K17323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 477.0
CMS2_k127_3852361_13 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 452.0
CMS2_k127_3852361_14 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 441.0
CMS2_k127_3852361_15 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 432.0
CMS2_k127_3852361_16 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 411.0
CMS2_k127_3852361_17 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 419.0
CMS2_k127_3852361_18 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 385.0
CMS2_k127_3852361_19 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 390.0
CMS2_k127_3852361_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.577e-315 984.0
CMS2_k127_3852361_20 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 378.0
CMS2_k127_3852361_21 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 351.0
CMS2_k127_3852361_22 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 346.0
CMS2_k127_3852361_23 DeoR C terminal sensor domain K02444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 338.0
CMS2_k127_3852361_24 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 333.0
CMS2_k127_3852361_25 Luciferase-like monooxygenase K17228 - 1.14.14.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 333.0
CMS2_k127_3852361_26 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 314.0
CMS2_k127_3852361_27 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 313.0
CMS2_k127_3852361_28 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 306.0
CMS2_k127_3852361_29 long-chain fatty acid transport protein K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 315.0
CMS2_k127_3852361_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 2.896e-237 741.0
CMS2_k127_3852361_30 Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 302.0
CMS2_k127_3852361_31 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 303.0
CMS2_k127_3852361_32 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 291.0
CMS2_k127_3852361_33 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 292.0
CMS2_k127_3852361_34 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002952 280.0
CMS2_k127_3852361_35 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001878 284.0
CMS2_k127_3852361_36 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002659 276.0
CMS2_k127_3852361_37 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000371 265.0
CMS2_k127_3852361_38 PPIC-type PPIASE domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000001036 273.0
CMS2_k127_3852361_39 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004158 264.0
CMS2_k127_3852361_4 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 6.714e-205 648.0
CMS2_k127_3852361_40 FAD binding domain in molybdopterin dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001277 252.0
CMS2_k127_3852361_41 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000001065 208.0
CMS2_k127_3852361_42 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000007495 203.0
CMS2_k127_3852361_43 Rhamnan synthesis protein F K07272 - - 0.00000000000000000000000000000000000000000000000000000448 203.0
CMS2_k127_3852361_44 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000001015 195.0
CMS2_k127_3852361_45 Rhamnan synthesis protein F K07272 - - 0.000000000000000000000000000000000000000000000000001258 195.0
CMS2_k127_3852361_46 - - - - 0.00000000000000000000000000000000000000000000000008679 190.0
CMS2_k127_3852361_47 transcriptional - - - 0.000000000000000000000000000000000000000000000001345 177.0
CMS2_k127_3852361_48 small integral membrane protein - - - 0.00000000000000000000000000000000000001811 145.0
CMS2_k127_3852361_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 597.0
CMS2_k127_3852361_50 GYD domain - - - 0.000000000000000000000000000003706 123.0
CMS2_k127_3852361_51 glycosyl transferase family 2 K07011 - - 0.00000000000000000000000003999 118.0
CMS2_k127_3852361_52 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000007167 105.0
CMS2_k127_3852361_53 ThiS family K03154 - - 0.000000000000002508 77.0
CMS2_k127_3852361_54 - - - - 0.000000000001931 72.0
CMS2_k127_3852361_55 - - - - 0.000007305 58.0
CMS2_k127_3852361_6 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 548.0
CMS2_k127_3852361_7 Belongs to the ABC transporter superfamily K17325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 516.0
CMS2_k127_3852361_8 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 551.0
CMS2_k127_3852361_9 COG1175 ABC-type sugar transport systems permease components K17322 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 490.0
CMS2_k127_3876585_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K21834 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 553.0
CMS2_k127_3876585_1 Acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 515.0
CMS2_k127_3876585_10 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000000000000000000001378 188.0
CMS2_k127_3876585_11 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.00000000000000000000000000000000000001415 159.0
CMS2_k127_3876585_12 - - - - 0.00000000000000000000001108 109.0
CMS2_k127_3876585_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000001739 79.0
CMS2_k127_3876585_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 449.0
CMS2_k127_3876585_3 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 373.0
CMS2_k127_3876585_4 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 332.0
CMS2_k127_3876585_5 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 304.0
CMS2_k127_3876585_6 formate dehydrogenase K00127 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 297.0
CMS2_k127_3876585_7 nitrate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001211 268.0
CMS2_k127_3876585_8 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005458 264.0
CMS2_k127_3876585_9 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000001591 225.0
CMS2_k127_3939685_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1266.0
CMS2_k127_3939685_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 5.268e-311 969.0
CMS2_k127_3939685_10 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 579.0
CMS2_k127_3939685_11 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 450.0
CMS2_k127_3939685_12 COG0616 Periplasmic serine proteases (ClpP class) K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 454.0
CMS2_k127_3939685_13 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009769 419.0
CMS2_k127_3939685_14 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001,K19745 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 420.0
CMS2_k127_3939685_15 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 426.0
CMS2_k127_3939685_16 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 418.0
CMS2_k127_3939685_17 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 416.0
CMS2_k127_3939685_18 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 379.0
CMS2_k127_3939685_19 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K20023 - 4.2.1.156,4.2.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 365.0
CMS2_k127_3939685_2 Hydantoinase/oxoprolinase - - - 3.356e-299 931.0
CMS2_k127_3939685_20 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 357.0
CMS2_k127_3939685_21 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 334.0
CMS2_k127_3939685_22 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 330.0
CMS2_k127_3939685_23 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 322.0
CMS2_k127_3939685_24 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 321.0
CMS2_k127_3939685_25 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 296.0
CMS2_k127_3939685_26 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000106 263.0
CMS2_k127_3939685_27 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001587 236.0
CMS2_k127_3939685_28 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000008865 235.0
CMS2_k127_3939685_29 transcriptional regulators K22042 - - 0.000000000000000000000000000000000000004576 147.0
CMS2_k127_3939685_3 Hydantoinase B/oxoprolinase - - - 4.67e-292 914.0
CMS2_k127_3939685_30 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000006768 151.0
CMS2_k127_3939685_31 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000001956 147.0
CMS2_k127_3939685_32 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000001998 97.0
CMS2_k127_3939685_33 Paraquat-inducible protein A K03808 - - 0.000000000000000003581 93.0
CMS2_k127_3939685_34 COG0607 Rhodanese-related sulfurtransferase - - - 0.0000000000000001119 84.0
CMS2_k127_3939685_35 TPR repeat - - - 0.0000000000001817 79.0
CMS2_k127_3939685_36 TPR repeat - - - 0.0000000009285 67.0
CMS2_k127_3939685_4 Tripartite tricarboxylate transporter TctA family K07793 - - 5.108e-258 802.0
CMS2_k127_3939685_5 Branched-chain amino acid transport system / permease component K01997,K01998 - - 1.254e-243 768.0
CMS2_k127_3939685_6 Domain of unknown function (DUF2088) - - - 1.779e-199 629.0
CMS2_k127_3939685_7 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 3.787e-199 632.0
CMS2_k127_3939685_8 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 609.0
CMS2_k127_3939685_9 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 596.0
CMS2_k127_3971451_0 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 512.0
CMS2_k127_3971451_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 327.0
CMS2_k127_3971451_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 302.0
CMS2_k127_4064973_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 6.269e-248 785.0
CMS2_k127_4064973_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 8.026e-218 685.0
CMS2_k127_4064973_10 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000000002045 196.0
CMS2_k127_4064973_11 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000001309 101.0
CMS2_k127_4064973_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 574.0
CMS2_k127_4064973_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 524.0
CMS2_k127_4064973_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 458.0
CMS2_k127_4064973_5 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 408.0
CMS2_k127_4064973_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 388.0
CMS2_k127_4064973_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 380.0
CMS2_k127_4064973_8 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 352.0
CMS2_k127_4064973_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 338.0
CMS2_k127_4081136_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 4.016e-259 815.0
CMS2_k127_4081136_1 D-galactarate dehydratase / Altronate hydrolase, C terminus - - - 9.752e-242 760.0
CMS2_k127_4081136_10 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 332.0
CMS2_k127_4081136_11 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 319.0
CMS2_k127_4081136_12 Catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate-6-phosphate from 2-dehydro-3-deoxy-D-gluconate K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 300.0
CMS2_k127_4081136_13 ABC transporter K10439 - - 0.000000000000000000000000000000000003407 138.0
CMS2_k127_4081136_14 PAS domain - - - 0.00000000000000000000000000009708 123.0
CMS2_k127_4081136_2 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 1.759e-218 692.0
CMS2_k127_4081136_3 COG3970 Fumarylacetoacetate (FAA) hydrolase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 496.0
CMS2_k127_4081136_4 Gluconolactonase K01053,K14274 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 472.0
CMS2_k127_4081136_5 SMP-30/Gluconolaconase/LRE-like region K01053,K02352 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 438.0
CMS2_k127_4081136_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 421.0
CMS2_k127_4081136_7 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 422.0
CMS2_k127_4081136_8 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 426.0
CMS2_k127_4081136_9 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 374.0
CMS2_k127_4089305_0 COG2217 Cation transport ATPase K01533 - 3.6.3.4 1.059e-273 863.0
CMS2_k127_4089305_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 3.299e-264 819.0
CMS2_k127_4089305_10 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 491.0
CMS2_k127_4089305_11 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 477.0
CMS2_k127_4089305_12 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 428.0
CMS2_k127_4089305_13 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 413.0
CMS2_k127_4089305_14 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 410.0
CMS2_k127_4089305_15 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 400.0
CMS2_k127_4089305_16 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 388.0
CMS2_k127_4089305_17 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 378.0
CMS2_k127_4089305_18 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 351.0
CMS2_k127_4089305_19 Ankyrin repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 348.0
CMS2_k127_4089305_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.02e-202 649.0
CMS2_k127_4089305_20 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 338.0
CMS2_k127_4089305_21 PFAM Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 351.0
CMS2_k127_4089305_22 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 299.0
CMS2_k127_4089305_23 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008044 280.0
CMS2_k127_4089305_24 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001038 282.0
CMS2_k127_4089305_25 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009541 275.0
CMS2_k127_4089305_26 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001235 263.0
CMS2_k127_4089305_27 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000126 254.0
CMS2_k127_4089305_28 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009222 249.0
CMS2_k127_4089305_29 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003094 233.0
CMS2_k127_4089305_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 617.0
CMS2_k127_4089305_30 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000008141 217.0
CMS2_k127_4089305_31 - - - - 0.0000000000000000000000000000000000000000000000000003213 188.0
CMS2_k127_4089305_32 PFAM Excinuclease ABC, C subunit K07461 - - 0.0000000000000000000000000000000000000001062 152.0
CMS2_k127_4089305_33 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000000000003833 134.0
CMS2_k127_4089305_34 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000074 134.0
CMS2_k127_4089305_35 FixH - - - 0.00000000000000000000000000001943 130.0
CMS2_k127_4089305_36 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000005725 105.0
CMS2_k127_4089305_37 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000005624 90.0
CMS2_k127_4089305_38 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000001327 79.0
CMS2_k127_4089305_39 Cytochrome oxidase maturation protein - - - 0.000000000000001956 77.0
CMS2_k127_4089305_4 Nitrogen fixation protein fixG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006652 607.0
CMS2_k127_4089305_40 - - - - 0.000000000001884 74.0
CMS2_k127_4089305_42 - - - - 0.0000006313 59.0
CMS2_k127_4089305_43 PFAM chemotaxis K03406,K07216 - - 0.0005888 50.0
CMS2_k127_4089305_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004583 599.0
CMS2_k127_4089305_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 598.0
CMS2_k127_4089305_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 577.0
CMS2_k127_4089305_8 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 582.0
CMS2_k127_4089305_9 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 537.0
CMS2_k127_4115683_0 single-stranded-DNA-specific exonuclease recJ K07462 - - 7.245e-235 742.0
CMS2_k127_4115683_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 8.574e-235 736.0
CMS2_k127_4115683_10 Scavenger mRNA decapping enzyme C-term binding - - - 0.00000000000000000000000000000000000000002114 162.0
CMS2_k127_4115683_11 Cell wall hydrolyses involved in spore germination - - - 0.0000000000000000000000000000000000000002543 158.0
CMS2_k127_4115683_12 Cell wall hydrolyses involved in spore germination - - - 0.000000000000000000000000000000000000001391 159.0
CMS2_k127_4115683_13 GDYXXLXY protein - - - 0.0000000000000000000000000001365 122.0
CMS2_k127_4115683_14 Protein required for attachment to host cells - - - 0.0000000000000000000000000006997 120.0
CMS2_k127_4115683_15 - - - - 0.00002049 55.0
CMS2_k127_4115683_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 400.0
CMS2_k127_4115683_3 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 371.0
CMS2_k127_4115683_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 346.0
CMS2_k127_4115683_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 297.0
CMS2_k127_4115683_6 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 305.0
CMS2_k127_4115683_7 COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins K11532 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000002582 207.0
CMS2_k127_4115683_8 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000000001528 186.0
CMS2_k127_4115683_9 FR47-like protein - - - 0.000000000000000000000000000000000000000002049 161.0
CMS2_k127_4118373_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 482.0
CMS2_k127_4118373_1 COG1062 Zn-dependent alcohol dehydrogenases, class III K00153 - 1.1.1.306 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 449.0
CMS2_k127_4118373_2 transcriptional regulator K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 349.0
CMS2_k127_4137177_0 Cytochrome C and Quinol oxidase polypeptide I K02274 - 1.9.3.1 9.432e-258 806.0
CMS2_k127_4137177_1 FMN_bind K19339 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 612.0
CMS2_k127_4137177_10 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000002868 164.0
CMS2_k127_4137177_11 - - - - 0.0000000001758 66.0
CMS2_k127_4137177_12 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000007376 56.0
CMS2_k127_4137177_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 572.0
CMS2_k127_4137177_3 nitrite reductase K15864 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1,1.7.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 361.0
CMS2_k127_4137177_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006806 333.0
CMS2_k127_4137177_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 302.0
CMS2_k127_4137177_6 protein involved in response to NO K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004683 273.0
CMS2_k127_4137177_7 cytochrome c oxidase (Subunit II) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001141 248.0
CMS2_k127_4137177_8 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000001716 235.0
CMS2_k127_4137177_9 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.00000000000000000000000000000000000000000000000000000005644 205.0
CMS2_k127_4140793_0 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 544.0
CMS2_k127_4140793_1 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000121 144.0
CMS2_k127_4140793_2 - - - - 0.00000000000000000000000000000000114 138.0
CMS2_k127_4140793_3 oxygen carrier activity K07216 - - 0.0000000000000000000000004644 111.0
CMS2_k127_4146047_0 AMP-binding enzyme C-terminal domain K00666 - - 6.102e-264 827.0
CMS2_k127_4146047_1 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 502.0
CMS2_k127_4146047_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006456 276.0
CMS2_k127_4151078_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.403e-273 852.0
CMS2_k127_4151078_1 COG0471 Di- and tricarboxylate transporters - - - 1.857e-200 641.0
CMS2_k127_4151078_10 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000001634 218.0
CMS2_k127_4151078_11 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000004674 214.0
CMS2_k127_4151078_12 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.000000000000000000000000000000000000000000000549 188.0
CMS2_k127_4151078_13 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000002966 158.0
CMS2_k127_4151078_14 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000001723 103.0
CMS2_k127_4151078_15 nuclease - - - 0.0000007089 57.0
CMS2_k127_4151078_16 Transposase K07486 - - 0.0001086 45.0
CMS2_k127_4151078_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 444.0
CMS2_k127_4151078_3 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 421.0
CMS2_k127_4151078_4 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 389.0
CMS2_k127_4151078_5 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 380.0
CMS2_k127_4151078_6 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000113 259.0
CMS2_k127_4151078_7 Transposase K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002756 241.0
CMS2_k127_4151078_8 Alanine acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003468 246.0
CMS2_k127_4151078_9 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000007782 227.0
CMS2_k127_4163695_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.079e-263 826.0
CMS2_k127_4163695_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.88e-263 819.0
CMS2_k127_4163695_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 360.0
CMS2_k127_4163695_3 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 360.0
CMS2_k127_4163695_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 307.0
CMS2_k127_4163695_5 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 304.0
CMS2_k127_4163695_6 Protein of unknown function (DUF3105) - - - 0.00000000000000000000000000000000000000000000000000498 187.0
CMS2_k127_4163695_7 COG0790 FOG TPR repeat, SEL1 subfamily - - - 0.00009372 53.0
CMS2_k127_4177125_0 HELICc2 K03722 - 3.6.4.12 0.0 1118.0
CMS2_k127_4177125_1 Belongs to the heme-copper respiratory oxidase family K04561 - 1.7.2.5 0.0 1088.0
CMS2_k127_4177125_10 Protein conserved in bacteria K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007667 486.0
CMS2_k127_4177125_11 fad dependent oxidoreductase K09471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 484.0
CMS2_k127_4177125_12 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 473.0
CMS2_k127_4177125_13 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 471.0
CMS2_k127_4177125_14 e1 component (alpha subunit) K00161 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004595 452.0
CMS2_k127_4177125_15 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K02049,K10831 - 3.6.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 420.0
CMS2_k127_4177125_16 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 409.0
CMS2_k127_4177125_17 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 385.0
CMS2_k127_4177125_18 COG3264 Small-conductance mechanosensitive channel K05802 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 377.0
CMS2_k127_4177125_19 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 362.0
CMS2_k127_4177125_2 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 1.14e-298 924.0
CMS2_k127_4177125_20 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 359.0
CMS2_k127_4177125_21 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 346.0
CMS2_k127_4177125_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 362.0
CMS2_k127_4177125_23 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 334.0
CMS2_k127_4177125_24 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000715 327.0
CMS2_k127_4177125_25 N-Acetylmuramoyl-L-alanine amidase K01447,K03806,K11066 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 312.0
CMS2_k127_4177125_26 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 303.0
CMS2_k127_4177125_27 Cytochrome c biogenesis protein K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003373 273.0
CMS2_k127_4177125_28 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001245 252.0
CMS2_k127_4177125_29 periplasmic protein thiol disulfide K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003765 246.0
CMS2_k127_4177125_3 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 1.736e-268 835.0
CMS2_k127_4177125_30 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008966 254.0
CMS2_k127_4177125_31 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000004058 236.0
CMS2_k127_4177125_32 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000000171 225.0
CMS2_k127_4177125_33 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000002371 227.0
CMS2_k127_4177125_34 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000002623 205.0
CMS2_k127_4177125_35 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000006491 192.0
CMS2_k127_4177125_36 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000007435 187.0
CMS2_k127_4177125_37 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000005666 169.0
CMS2_k127_4177125_38 RF-1 domain K15034 - - 0.000000000000000000000000000000000000000000000851 169.0
CMS2_k127_4177125_39 YbaK prolyl-tRNA synthetase associated region - - - 0.0000000000000000000000000000000000000000001781 165.0
CMS2_k127_4177125_4 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 6.789e-246 774.0
CMS2_k127_4177125_40 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 0.000000000000000000000000000000000000000002067 156.0
CMS2_k127_4177125_41 Transcriptional regulator - - - 0.000000000000000000000000000000000000000004287 158.0
CMS2_k127_4177125_42 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000974 156.0
CMS2_k127_4177125_43 Cytochrome c - - - 0.00000000000000000000000000000000417 135.0
CMS2_k127_4177125_44 Acetyltransferase, GNAT K06977 - - 0.000000000000000000000000000000004885 134.0
CMS2_k127_4177125_45 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.0000000000000000000000000000001616 143.0
CMS2_k127_4177125_46 - - - - 0.000000000000000000000000000004242 130.0
CMS2_k127_4177125_47 - - - - 0.0000000000000000000000000001062 126.0
CMS2_k127_4177125_48 Protein of unknown function (DUF1622) - - - 0.000000000000000000000000001361 115.0
CMS2_k127_4177125_49 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000001394 117.0
CMS2_k127_4177125_5 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 2.655e-235 744.0
CMS2_k127_4177125_50 - - - - 0.00000000000000000003572 96.0
CMS2_k127_4177125_51 Protein of Unknown function (DUF2784) - - - 0.000000000004958 71.0
CMS2_k127_4177125_52 Short C-terminal domain K08982 - - 0.00000000006944 66.0
CMS2_k127_4177125_53 Protein of unknown function (DUF1573) - - - 0.0000000001097 70.0
CMS2_k127_4177125_54 Short C-terminal domain - - - 0.00000000677 62.0
CMS2_k127_4177125_55 monooxygenase activity - - - 0.0000003559 55.0
CMS2_k127_4177125_56 Protein of unknown function (DUF1573) - - - 0.00002077 52.0
CMS2_k127_4177125_6 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 595.0
CMS2_k127_4177125_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 580.0
CMS2_k127_4177125_8 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 503.0
CMS2_k127_4177125_9 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 485.0
CMS2_k127_4212321_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.165e-251 780.0
CMS2_k127_4212321_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 7.527e-229 724.0
CMS2_k127_4212321_10 COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism K06023 - - 0.000000000000000000000000000000002291 136.0
CMS2_k127_4212321_11 COG1925 Phosphotransferase system, HPr-related proteins K11189 - - 0.000000000000000000000000002522 115.0
CMS2_k127_4212321_12 Probable cobalt transporter subunit (CbtB) - - - 0.0000002369 57.0
CMS2_k127_4212321_13 cobalt transporter, subunit CbtA - - - 0.000003876 52.0
CMS2_k127_4212321_2 PAS PAC domain-containing protein - - - 8.399e-212 685.0
CMS2_k127_4212321_3 Stimulus-sensing domain K14980 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 537.0
CMS2_k127_4212321_4 reductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 463.0
CMS2_k127_4212321_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K14981 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 381.0
CMS2_k127_4212321_6 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 337.0
CMS2_k127_4212321_7 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 297.0
CMS2_k127_4212321_8 COG2893 Phosphotransferase system, mannose fructose-specific component IIA K02793 - 2.7.1.191 0.0000000000000000000000000000000000000000000000000000004072 196.0
CMS2_k127_4212321_9 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000000004639 178.0
CMS2_k127_4227143_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1775.0
CMS2_k127_4227143_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1511.0
CMS2_k127_4227143_10 Bacterial protein of unknown function (DUF853) K06915 - - 4.769e-198 630.0
CMS2_k127_4227143_11 ABC-type multidrug transport system, ATPase and permease K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 592.0
CMS2_k127_4227143_12 helix_turn_helix gluconate operon transcriptional repressor K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 567.0
CMS2_k127_4227143_13 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 561.0
CMS2_k127_4227143_14 FAD binding domain K22270 - 1.14.13.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 529.0
CMS2_k127_4227143_15 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 522.0
CMS2_k127_4227143_16 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 519.0
CMS2_k127_4227143_17 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 491.0
CMS2_k127_4227143_18 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 485.0
CMS2_k127_4227143_19 Dihydrodipicolinate synthetase family K01714,K13876 - 4.2.1.43,4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 462.0
CMS2_k127_4227143_2 Belongs to the ClpA ClpB family K03694 - - 0.0 1199.0
CMS2_k127_4227143_20 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 447.0
CMS2_k127_4227143_21 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005622 442.0
CMS2_k127_4227143_22 3-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 426.0
CMS2_k127_4227143_23 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 414.0
CMS2_k127_4227143_24 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 411.0
CMS2_k127_4227143_25 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 411.0
CMS2_k127_4227143_26 4Fe-4S dicluster domain K00184,K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 392.0
CMS2_k127_4227143_27 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 386.0
CMS2_k127_4227143_28 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 392.0
CMS2_k127_4227143_29 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 370.0
CMS2_k127_4227143_3 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 2.666e-241 762.0
CMS2_k127_4227143_30 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 359.0
CMS2_k127_4227143_31 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 352.0
CMS2_k127_4227143_32 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 353.0
CMS2_k127_4227143_33 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 348.0
CMS2_k127_4227143_34 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 346.0
CMS2_k127_4227143_35 peroxidase K07223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 343.0
CMS2_k127_4227143_36 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 329.0
CMS2_k127_4227143_37 DMSO reductase anchor subunit (DmsC) K21309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 331.0
CMS2_k127_4227143_38 Phosphate K00625,K00634 - 2.3.1.19,2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 337.0
CMS2_k127_4227143_39 ammonia monooxygenase K07120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 317.0
CMS2_k127_4227143_4 ABC transporter K06158 - - 3.33e-229 726.0
CMS2_k127_4227143_40 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 314.0
CMS2_k127_4227143_41 Predicted permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 310.0
CMS2_k127_4227143_42 COG1560 Lauroyl myristoyl acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 302.0
CMS2_k127_4227143_43 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15268 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 291.0
CMS2_k127_4227143_44 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001328 282.0
CMS2_k127_4227143_45 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006721 283.0
CMS2_k127_4227143_46 protein conserved in bacteria K09778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004925 277.0
CMS2_k127_4227143_47 COG0593 ATPase involved in DNA replication initiation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004747 250.0
CMS2_k127_4227143_48 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000134 253.0
CMS2_k127_4227143_49 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001077 258.0
CMS2_k127_4227143_5 Aldehyde dehydrogenase family K00128 - 1.2.1.3 2.494e-227 713.0
CMS2_k127_4227143_50 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007496 245.0
CMS2_k127_4227143_51 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000001248 226.0
CMS2_k127_4227143_52 Putative transmembrane protein (Alph_Pro_TM) - - - 0.0000000000000000000000000000000000000000000000000000000000001674 223.0
CMS2_k127_4227143_53 COG0784 FOG CheY-like receiver K11443 - - 0.0000000000000000000000000000000000000000000000000000000000102 208.0
CMS2_k127_4227143_54 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000000000000000000000000000000000000000000000000003489 220.0
CMS2_k127_4227143_55 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000001454 207.0
CMS2_k127_4227143_56 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000001098 207.0
CMS2_k127_4227143_57 Uncharacterized protein conserved in bacteria (DUF2066) - - - 0.0000000000000000000000000000000000000000000000000000004475 207.0
CMS2_k127_4227143_58 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000001103 197.0
CMS2_k127_4227143_59 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000003016 195.0
CMS2_k127_4227143_6 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.26e-224 702.0
CMS2_k127_4227143_60 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000000000001172 187.0
CMS2_k127_4227143_61 Domain of unknown function (DUF1849) - - - 0.000000000000000000000000000000000000000000000000002432 192.0
CMS2_k127_4227143_62 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000000000000000000000000000000000000000000004254 194.0
CMS2_k127_4227143_63 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000000007276 183.0
CMS2_k127_4227143_64 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000004236 180.0
CMS2_k127_4227143_65 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000001172 178.0
CMS2_k127_4227143_66 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000000001204 178.0
CMS2_k127_4227143_67 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000002126 175.0
CMS2_k127_4227143_68 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000002407 170.0
CMS2_k127_4227143_69 Protein of unknown function DUF126 K09128 - - 0.000000000000000000000000000000000000000000008065 172.0
CMS2_k127_4227143_7 sulfite reductase K11180 - 1.8.99.5 4.21e-224 702.0
CMS2_k127_4227143_70 NADH ubiquinone oxidoreductase 17.2 kD subunit - - - 0.0000000000000000000000000000000000000000003264 160.0
CMS2_k127_4227143_71 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000002637 159.0
CMS2_k127_4227143_72 NfeD-like C-terminal, partner-binding K07340 - - 0.0000000000000000000000000000000000000127 150.0
CMS2_k127_4227143_73 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000006186 145.0
CMS2_k127_4227143_74 protein conserved in bacteria - - - 0.00000000000000000000000000000000006993 138.0
CMS2_k127_4227143_75 membrane transporter protein K07090 - - 0.00000000000000000000000000000000008132 143.0
CMS2_k127_4227143_76 B-1 B cell differentiation - - - 0.0000000000000000000000000000000001074 150.0
CMS2_k127_4227143_77 Usg-like family - - - 0.000000000000000000000000000000006079 130.0
CMS2_k127_4227143_78 Transcriptional regulator ArsR family - - - 0.00000000000000000000000000001003 121.0
CMS2_k127_4227143_79 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000001029 115.0
CMS2_k127_4227143_8 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 1.655e-217 683.0
CMS2_k127_4227143_80 COG0438 Glycosyltransferase - - - 0.0000000000000000000000000005978 126.0
CMS2_k127_4227143_81 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000009132 117.0
CMS2_k127_4227143_82 Cbs domain - - - 0.0000000000000000000000001457 111.0
CMS2_k127_4227143_83 GYD domain - - - 0.000000000000000000000002956 106.0
CMS2_k127_4227143_84 FecR protein - - - 0.00000000000000000003544 100.0
CMS2_k127_4227143_85 E-Z type HEAT repeats - - - 0.0000000000000000000381 104.0
CMS2_k127_4227143_86 - - - - 0.00000000000000000049 95.0
CMS2_k127_4227143_87 pathogenesis - - - 0.000000000000000001228 95.0
CMS2_k127_4227143_88 Rhodanese-related sulfurtransferase - - - 0.00000000000000001974 86.0
CMS2_k127_4227143_89 - - - - 0.000000000000006771 77.0
CMS2_k127_4227143_9 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 1.95e-203 650.0
CMS2_k127_4227143_90 - - - - 0.00000000000003301 74.0
CMS2_k127_4227143_92 - - - - 0.00000000000496 74.0
CMS2_k127_4227143_93 Short chain dehydrogenase K00059 - 1.1.1.100 0.0000000004214 60.0
CMS2_k127_4227143_94 Phasin protein - - - 0.0000001584 60.0
CMS2_k127_4227143_95 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.0000002305 63.0
CMS2_k127_4227143_96 Domain of unknown function (DUF4389) - - - 0.0001533 51.0
CMS2_k127_424745_0 belongs to the aldehyde dehydrogenase family - - - 5.193e-255 792.0
CMS2_k127_424745_1 COG4176 ABC-type proline glycine betaine transport system, permease component K02001 - - 1.704e-217 695.0
CMS2_k127_424745_10 COG0534 Na -driven multidrug efflux pump K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 450.0
CMS2_k127_424745_11 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 445.0
CMS2_k127_424745_12 ornithine cyclodeaminase K01750 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016638,GO:0016639,GO:0055114 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 383.0
CMS2_k127_424745_13 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 366.0
CMS2_k127_424745_14 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 360.0
CMS2_k127_424745_15 Glycine betaine proline ABC transporter, periplasmic substrate-binding protein K02002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 358.0
CMS2_k127_424745_16 COG0604 NADPH quinone reductase and related Zn-dependent K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 313.0
CMS2_k127_424745_17 Alpha beta hydrolase K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001351 279.0
CMS2_k127_424745_18 transcriptional regulator K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008282 246.0
CMS2_k127_424745_19 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000003339 198.0
CMS2_k127_424745_2 acyl-CoA dehydrogenase - - - 6.752e-216 676.0
CMS2_k127_424745_20 Acetyltransferase (GNAT) domain K03824 - - 0.00000000000000000000000000000000000000000000192 178.0
CMS2_k127_424745_21 EamA-like transporter family - - - 0.0000000000000000000000000000000000000505 156.0
CMS2_k127_424745_22 Belongs to the universal stress protein A family - - - 0.00000000000000000000003284 108.0
CMS2_k127_424745_23 Type VI secretion system VasI, EvfG, VC_A0118 K11909 - - 0.0000000000000000000004874 104.0
CMS2_k127_424745_24 FAD dependent oxidoreductase - - - 0.0000000000001013 71.0
CMS2_k127_424745_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005444 586.0
CMS2_k127_424745_4 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006916 570.0
CMS2_k127_424745_5 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0016740,GO:0016765,GO:0016829,GO:0016846 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009914 562.0
CMS2_k127_424745_6 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 563.0
CMS2_k127_424745_7 COG2309 Leucyl aminopeptidase (aminopeptidase T) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 520.0
CMS2_k127_424745_8 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K00830,K00839,K03430 GO:0003674,GO:0003824 2.6.1.112,2.6.1.37,2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 455.0
CMS2_k127_424745_9 COG4175 ABC-type proline glycine betaine transport system, ATPase component K02000 - 3.6.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 451.0
CMS2_k127_4268498_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 1.896e-302 940.0
CMS2_k127_4268498_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 3.921e-288 894.0
CMS2_k127_4268498_10 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009022 271.0
CMS2_k127_4268498_11 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001252 265.0
CMS2_k127_4268498_12 Metal dependent phosphohydrolases with conserved 'HD' motif. K06952 - - 0.00000000000000000000000000000000000000000000000000000000000000000003151 238.0
CMS2_k127_4268498_13 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000000000000000000000000000000000000000000000000002859 208.0
CMS2_k127_4268498_14 Cytochrome P460 - - - 0.00000000000000000000000000000000000000000000000002106 190.0
CMS2_k127_4268498_15 COG1607 Acyl-CoA hydrolase K10806 - - 0.00000000000000000000000000000000000000000000009315 171.0
CMS2_k127_4268498_16 - - - - 0.00000000000000000000000000000000000002346 147.0
CMS2_k127_4268498_17 Cephalosporin hydroxylase - - - 0.0000000000000000000000000000000000005472 149.0
CMS2_k127_4268498_18 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000001338 134.0
CMS2_k127_4268498_19 - - - - 0.000000000000000000000000000000001691 136.0
CMS2_k127_4268498_2 glutamine synthetase K01915 - 6.3.1.2 1.137e-246 773.0
CMS2_k127_4268498_20 OmpA family - - - 0.00000000004823 71.0
CMS2_k127_4268498_3 PFAM Aminotransferase class I and II - - - 4.113e-211 661.0
CMS2_k127_4268498_4 Belongs to the DEAD box helicase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 539.0
CMS2_k127_4268498_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 441.0
CMS2_k127_4268498_6 COG0025 NhaP-type Na H and K H antiporters K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 445.0
CMS2_k127_4268498_7 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 398.0
CMS2_k127_4268498_8 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 316.0
CMS2_k127_4268498_9 protein histidine kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007282 316.0
CMS2_k127_4289904_0 carbon monoxide dehydrogenase K03520 - 1.2.5.3 0.0 1053.0
CMS2_k127_4289904_1 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 612.0
CMS2_k127_4289904_2 Belongs to the ABC transporter superfamily K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 521.0
CMS2_k127_4289904_3 COG0395 ABC-type sugar transport system, permease component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 463.0
CMS2_k127_4289904_4 ABC transporter permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 439.0
CMS2_k127_4289904_5 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 381.0
CMS2_k127_4289904_6 regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001532 259.0
CMS2_k127_4289904_7 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000002522 238.0
CMS2_k127_4289904_8 carbon monoxide dehydrogenase K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001971 243.0
CMS2_k127_4289904_9 NIPSNAP family containing protein - - - 0.00000000000000000000000000000000000000000005904 163.0
CMS2_k127_4354536_0 Domain of unknown function (DUF4445) - - - 2.563e-290 907.0
CMS2_k127_4354536_1 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 512.0
CMS2_k127_4354536_10 Acts on guanine, xanthine and to a lesser extent hypoxanthine K00769 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000000000000000004715 259.0
CMS2_k127_4354536_11 D-isomer specific 2-hydroxyacid dehydrogenase K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000201 256.0
CMS2_k127_4354536_12 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000006968 252.0
CMS2_k127_4354536_13 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009648 255.0
CMS2_k127_4354536_14 Subtilase family K08651,K14645 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000000000000001422 273.0
CMS2_k127_4354536_15 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000007627 229.0
CMS2_k127_4354536_16 2-oxopent-4-enoate hydratase activity K02554 - 4.2.1.80 0.0000000000000000000000000000000000000000000004992 177.0
CMS2_k127_4354536_17 Virulence factor - - - 0.000000000000000000000000000002362 123.0
CMS2_k127_4354536_18 - - - - 0.00000001237 64.0
CMS2_k127_4354536_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 475.0
CMS2_k127_4354536_3 Predicted membrane protein (DUF2339) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 492.0
CMS2_k127_4354536_4 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000827 468.0
CMS2_k127_4354536_5 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 430.0
CMS2_k127_4354536_6 cobalamin binding protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 402.0
CMS2_k127_4354536_7 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 343.0
CMS2_k127_4354536_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002626 278.0
CMS2_k127_4354536_9 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004632 257.0
CMS2_k127_4360520_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1542.0
CMS2_k127_4360520_1 Belongs to the MT-A70-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 379.0
CMS2_k127_4360520_2 Restriction endonuclease BglII - - - 0.0000000000000000000000000000000000000000000000000000005579 203.0
CMS2_k127_4360520_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000001198 165.0
CMS2_k127_4360520_4 Protein of unknown function (DUF3108) - - - 0.000000000000000005241 95.0
CMS2_k127_4369758_0 RimK-like ATPgrasp N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 558.0
CMS2_k127_4369758_1 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 509.0
CMS2_k127_4369758_2 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 417.0
CMS2_k127_4369758_3 Pyridine nucleotide-disulphide oxidoreductase K17218,K17229 - 1.8.2.3,1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 397.0
CMS2_k127_4369758_4 Protein of unknown function (DUF1445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 386.0
CMS2_k127_4369758_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000002824 226.0
CMS2_k127_4369758_6 2OG-Fe(II) oxygenase superfamily K07336,K07394 - - 0.000000000000000000000000000000000000000000001769 172.0
CMS2_k127_4369758_7 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.000000000000000000000000000000000000000000011 164.0
CMS2_k127_4369758_8 Phosphoserine phosphatase - - - 0.0000000000000000000000001479 121.0
CMS2_k127_4369758_9 cytochrome K08738 - - 0.000000000000000000002377 97.0
CMS2_k127_437873_0 D-galactarate dehydratase / Altronate hydrolase, C terminus K16846 - 4.4.1.24 1.117e-212 664.0
CMS2_k127_437873_1 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 583.0
CMS2_k127_437873_10 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000004759 112.0
CMS2_k127_437873_11 Autotransporter beta-domain K12686 - - 0.00000000000000001384 87.0
CMS2_k127_437873_12 Autotransporter beta-domain K12686 - - 0.0000002661 63.0
CMS2_k127_437873_13 Autotransporter beta-domain K12686 - - 0.000007925 53.0
CMS2_k127_437873_2 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 406.0
CMS2_k127_437873_3 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 338.0
CMS2_k127_437873_4 Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine K05396,K17950 - 4.4.1.15,4.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 331.0
CMS2_k127_437873_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046,K00065 - 1.1.1.127,1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003508 275.0
CMS2_k127_437873_6 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001909 263.0
CMS2_k127_437873_7 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000003368 231.0
CMS2_k127_437873_8 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000002863 160.0
CMS2_k127_437873_9 SAF K16845 - 4.4.1.24 0.0000000000000000000000000000000000000008981 149.0
CMS2_k127_4396598_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 443.0
CMS2_k127_4396598_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K16843 - 1.1.1.310 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 351.0
CMS2_k127_4396598_2 Molecular chaperone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 312.0
CMS2_k127_4396598_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001773 267.0
CMS2_k127_4396598_4 Acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008624 260.0
CMS2_k127_4396598_5 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000116 245.0
CMS2_k127_4396598_6 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000005909 246.0
CMS2_k127_4396598_7 17 kDa outer membrane surface antigen - - - 0.000000000000000000000000000000000000000000000002705 179.0
CMS2_k127_44059_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 571.0
CMS2_k127_44059_1 COG0768 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 582.0
CMS2_k127_44059_10 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005625 259.0
CMS2_k127_44059_11 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000268 129.0
CMS2_k127_44059_12 - - - - 0.000000000000000000000009404 106.0
CMS2_k127_44059_13 secreted (periplasmic) protein - - - 0.00000000001485 76.0
CMS2_k127_44059_14 - - - - 0.0000004819 59.0
CMS2_k127_44059_15 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0003521 51.0
CMS2_k127_44059_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 503.0
CMS2_k127_44059_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 490.0
CMS2_k127_44059_4 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 465.0
CMS2_k127_44059_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 443.0
CMS2_k127_44059_6 aminopeptidase K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 429.0
CMS2_k127_44059_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 418.0
CMS2_k127_44059_8 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 415.0
CMS2_k127_44059_9 Amino Acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 370.0
CMS2_k127_4416619_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.693e-271 837.0
CMS2_k127_4416619_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 545.0
CMS2_k127_4416619_10 antisigma factor binding K03598 - - 0.000000000003972 76.0
CMS2_k127_4416619_2 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 512.0
CMS2_k127_4416619_3 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 489.0
CMS2_k127_4416619_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 481.0
CMS2_k127_4416619_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 408.0
CMS2_k127_4416619_6 signal transduction histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 378.0
CMS2_k127_4416619_7 Phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 305.0
CMS2_k127_4416619_8 Nitrogen regulatory protein P-II K04751,K04752 - - 0.000000000000000000000000000000000000000000006733 167.0
CMS2_k127_4416619_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000002546 136.0
CMS2_k127_4471798_0 Domain of unknown function DUF87 K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 490.0
CMS2_k127_4471798_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 455.0
CMS2_k127_4471798_10 PFAM regulatory protein MerR - - - 0.000000000000000000000000000001554 128.0
CMS2_k127_4471798_11 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000001832 107.0
CMS2_k127_4471798_12 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000134 96.0
CMS2_k127_4471798_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 403.0
CMS2_k127_4471798_3 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004109 266.0
CMS2_k127_4471798_4 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000000000000000000000001633 223.0
CMS2_k127_4471798_5 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000000000007898 187.0
CMS2_k127_4471798_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000001173 158.0
CMS2_k127_4471798_7 Adenylate cyclase - - - 0.00000000000000000000000000000000000000008557 157.0
CMS2_k127_4471798_8 repressor - - - 0.00000000000000000000000000000000000004769 153.0
CMS2_k127_4471798_9 Protein of unknown function (DUF2938) - - - 0.00000000000000000000000000000000001836 142.0
CMS2_k127_4511934_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019464,GO:0019752,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.4.2 0.0 1324.0
CMS2_k127_4511934_1 COG5265 ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components K06147 - - 5.282e-264 826.0
CMS2_k127_4511934_10 Belongs to the GcvT family K17486 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259 2.1.1.269 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 456.0
CMS2_k127_4511934_11 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 392.0
CMS2_k127_4511934_12 NMT1/THI5 like K15598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 381.0
CMS2_k127_4511934_13 transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 361.0
CMS2_k127_4511934_14 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 330.0
CMS2_k127_4511934_15 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 318.0
CMS2_k127_4511934_16 Bacterial periplasmic substrate-binding proteins K02030,K10022 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 284.0
CMS2_k127_4511934_17 Transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000019 247.0
CMS2_k127_4511934_18 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.000000000000000000000000000000000000000000000000000000000000001125 223.0
CMS2_k127_4511934_19 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000007178 215.0
CMS2_k127_4511934_2 ABC transporter transmembrane region K18893 - - 3.485e-259 812.0
CMS2_k127_4511934_21 Domain related to MnhB subunit of Na+/H+ antiporter K05566 - - 0.000000000000000000000000000000000000000000000000000001244 194.0
CMS2_k127_4511934_22 COG2111 Multisubunit Na H antiporter, MnhB subunit K05566 - - 0.0000000000000000000000000000000000000000000000000002503 197.0
CMS2_k127_4511934_23 COG1006 Multisubunit Na H antiporter, MnhC subunit K05567 - - 0.0000000000000000000000000000000000000000000000004972 179.0
CMS2_k127_4511934_24 - - - - 0.000000000000000000000000000000000000000000004642 173.0
CMS2_k127_4511934_25 COG1863 Multisubunit Na H antiporter MnhE subunit K05569 - - 0.0000000000000000000000000000000000000009926 156.0
CMS2_k127_4511934_26 Sigma-70, region 4 - - - 0.000000000000000000000000000000000000003845 152.0
CMS2_k127_4511934_27 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000002478 142.0
CMS2_k127_4511934_28 ETC complex I subunit K00329 - 1.6.5.3 0.00000000000000000000000000000004621 128.0
CMS2_k127_4511934_29 Multiple resistance and pH regulation protein F K05570 - - 0.00000000000000000000000000001129 126.0
CMS2_k127_4511934_3 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 3.017e-239 751.0
CMS2_k127_4511934_30 - - - - 0.0000000000000000000000000002728 115.0
CMS2_k127_4511934_31 AntiSigma factor - - - 0.0000000000000000000000004275 115.0
CMS2_k127_4511934_32 Na+/H+ antiporter subunit K05571 - - 0.0000000000000000000000006227 111.0
CMS2_k127_4511934_33 - - - - 0.000000000000003276 79.0
CMS2_k127_4511934_34 Na H antiporter - - - 0.00000000000002057 73.0
CMS2_k127_4511934_35 Protein of unknown function (DUF3238) - - - 0.0003308 53.0
CMS2_k127_4511934_36 - - - - 0.0003507 45.0
CMS2_k127_4511934_37 PFAM PBS lyase HEAT-like repeat - - - 0.0008372 50.0
CMS2_k127_4511934_4 Protein of unknown function (DUF1343) - - - 2.514e-221 692.0
CMS2_k127_4511934_5 Proton-conducting membrane transporter K05568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 613.0
CMS2_k127_4511934_6 Proton-conducting membrane transporter K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 586.0
CMS2_k127_4511934_7 Serine dehydratase K01752 - 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 572.0
CMS2_k127_4511934_8 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 502.0
CMS2_k127_4511934_9 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 468.0
CMS2_k127_4555713_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 5.664e-310 956.0
CMS2_k127_4555713_1 histidine ammonia-lyase K01745 GO:0003674,GO:0003824,GO:0004397,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564 4.3.1.3 1.645e-197 627.0
CMS2_k127_4555713_2 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 410.0
CMS2_k127_4555713_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 407.0
CMS2_k127_4555713_4 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 348.0
CMS2_k127_4555713_5 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 345.0
CMS2_k127_4555713_6 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 292.0
CMS2_k127_4555713_7 Domain of unknown function (DUF4202) - - - 0.000000000000000000000000000000000000000000000000000000000000228 218.0
CMS2_k127_4555713_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000003764 141.0
CMS2_k127_4555713_9 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000001528 99.0
CMS2_k127_4573625_0 COG1960 Acyl-CoA dehydrogenases K20035 - - 8.707e-229 723.0
CMS2_k127_4573625_1 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 605.0
CMS2_k127_4573625_10 Branched-chain amino acid aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000001794 212.0
CMS2_k127_4573625_11 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000000000000000000000003909 189.0
CMS2_k127_4573625_12 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000007188 169.0
CMS2_k127_4573625_13 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.0000000000000000000000000000000003189 139.0
CMS2_k127_4573625_14 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.000000000000000000001557 94.0
CMS2_k127_4573625_15 Potassium channel K21867 - - 0.000000000005767 72.0
CMS2_k127_4573625_2 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 520.0
CMS2_k127_4573625_3 WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 446.0
CMS2_k127_4573625_4 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 416.0
CMS2_k127_4573625_5 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 402.0
CMS2_k127_4573625_6 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 347.0
CMS2_k127_4573625_7 Signal Transduction Histidine Kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 344.0
CMS2_k127_4573625_8 Signal Transduction Histidine Kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 343.0
CMS2_k127_4573625_9 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 301.0
CMS2_k127_4668_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1003.0
CMS2_k127_4668_1 Trimethylamine methyltransferase (MTTB) - - - 9.566e-227 715.0
CMS2_k127_4668_10 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.0000000000000000000000000000000000000000000000000000000000001163 217.0
CMS2_k127_4668_11 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000006348 223.0
CMS2_k127_4668_12 Sel1-like repeats. K07126 - - 0.00000000000000000000003276 107.0
CMS2_k127_4668_13 oxygen carrier activity K07216 - - 0.000000000000004739 80.0
CMS2_k127_4668_14 Flp Fap pilin component K02651 - - 0.000000001596 60.0
CMS2_k127_4668_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 571.0
CMS2_k127_4668_3 aminotransferase class I and II K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 482.0
CMS2_k127_4668_4 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 328.0
CMS2_k127_4668_5 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 319.0
CMS2_k127_4668_6 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 324.0
CMS2_k127_4668_7 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000158 269.0
CMS2_k127_4668_8 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003171 256.0
CMS2_k127_4668_9 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000001587 236.0
CMS2_k127_4774392_0 RNA-metabolising metallo-beta-lactamase K07576 - - 4.04e-207 653.0
CMS2_k127_4774392_1 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 3.988e-201 635.0
CMS2_k127_4774392_10 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000003367 119.0
CMS2_k127_4774392_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 556.0
CMS2_k127_4774392_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 389.0
CMS2_k127_4774392_4 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005422 353.0
CMS2_k127_4774392_5 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000001135 218.0
CMS2_k127_4774392_6 Uncharacterized BCR, YaiI/YqxD family COG1671 K09768 - - 0.000000000000000000000000000000000000000000000000000000003922 202.0
CMS2_k127_4774392_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000001062 137.0
CMS2_k127_4774392_8 Protein of unknown function (DUF2799) - - - 0.0000000000000000000000000000006366 130.0
CMS2_k127_4774392_9 Cold shock K03704 - - 0.000000000000000000000000000007594 119.0
CMS2_k127_481110_0 Methionine synthase K00548 - 2.1.1.13 0.0 1604.0
CMS2_k127_481110_1 DNA helicase K03657 - 3.6.4.12 2.272e-252 788.0
CMS2_k127_481110_10 COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.0000000000000000000000000000001761 132.0
CMS2_k127_481110_11 Acetyltransferase (GNAT) domain - - - 0.00000000003963 70.0
CMS2_k127_481110_2 Chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000897 625.0
CMS2_k127_481110_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 431.0
CMS2_k127_481110_4 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 338.0
CMS2_k127_481110_5 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000372 268.0
CMS2_k127_481110_6 MlaA lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000658 220.0
CMS2_k127_481110_7 Sodium Bile acid symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000644 216.0
CMS2_k127_481110_8 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000001472 184.0
CMS2_k127_481110_9 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 0.0000000000000000000000000000000000000005508 148.0
CMS2_k127_4811168_0 Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism K00372,K02567 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 - 0.0 1366.0
CMS2_k127_4811168_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 9.702e-274 850.0
CMS2_k127_4811168_10 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 423.0
CMS2_k127_4811168_11 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 425.0
CMS2_k127_4811168_12 4Fe-4S binding domain K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 412.0
CMS2_k127_4811168_13 Belongs to the mandelate racemase muconate lactonizing enzyme family K19802 - 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 399.0
CMS2_k127_4811168_14 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 368.0
CMS2_k127_4811168_15 MauM NapG family ferredoxin-type protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 346.0
CMS2_k127_4811168_16 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009648 320.0
CMS2_k127_4811168_17 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 330.0
CMS2_k127_4811168_18 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 304.0
CMS2_k127_4811168_19 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 295.0
CMS2_k127_4811168_2 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 2.019e-236 737.0
CMS2_k127_4811168_20 Cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 286.0
CMS2_k127_4811168_21 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001669 264.0
CMS2_k127_4811168_22 Universal stress protein UspA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000214 254.0
CMS2_k127_4811168_23 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000303 249.0
CMS2_k127_4811168_24 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000001845 243.0
CMS2_k127_4811168_25 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006148 244.0
CMS2_k127_4811168_26 Oligopeptide/dipeptide transporter, C-terminal region K12371 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015232,GO:0015886,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.000000000000000000000000000000000000000000000000000000000000809 212.0
CMS2_k127_4811168_27 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.00000000000000000000000000000000000000000000000000000000001189 212.0
CMS2_k127_4811168_28 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000002101 182.0
CMS2_k127_4811168_29 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.000000000000000000000000000000000000000000002622 177.0
CMS2_k127_4811168_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 591.0
CMS2_k127_4811168_30 4Fe-4S dicluster domain K02572 - - 0.00000000000000000000000000000000000000000003224 168.0
CMS2_k127_4811168_31 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000000000000000000004511 152.0
CMS2_k127_4811168_32 cheY-homologous receiver domain K13589 - - 0.000000000000000000000000000002363 123.0
CMS2_k127_4811168_33 NapD protein K02570 - - 0.00000000000000000004347 92.0
CMS2_k127_4811168_34 Peptidase S24-like - - - 0.0000000000000000006917 94.0
CMS2_k127_4811168_35 - - - - 0.000000000000000004928 85.0
CMS2_k127_4811168_36 Peptidase S24-like - - - 0.000000002048 66.0
CMS2_k127_4811168_4 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 580.0
CMS2_k127_4811168_5 RNA ligase (ATP) activity K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 541.0
CMS2_k127_4811168_6 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 530.0
CMS2_k127_4811168_7 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 490.0
CMS2_k127_4811168_8 D-isomer specific 2-hydroxyacid dehydrogenase K03778,K18916 - 1.1.1.28,1.20.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 461.0
CMS2_k127_4811168_9 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 442.0
CMS2_k127_48482_0 Bacterial extracellular solute-binding proteins, family 5 Middle K12368 - - 2.358e-271 842.0
CMS2_k127_48482_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 2.712e-204 645.0
CMS2_k127_48482_10 Belongs to the ABC transporter superfamily K12371 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015232,GO:0015886,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 327.0
CMS2_k127_48482_2 5-aminolevulinic acid synthase K00643 - 2.3.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 573.0
CMS2_k127_48482_3 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 549.0
CMS2_k127_48482_4 COG0747 ABC-type dipeptide transport system, periplasmic component K12368 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006457,GO:0006810,GO:0006857,GO:0008150,GO:0009987,GO:0015833,GO:0020037,GO:0030288,GO:0030313,GO:0031975,GO:0033218,GO:0042277,GO:0042597,GO:0042886,GO:0042938,GO:0044464,GO:0046906,GO:0048037,GO:0051179,GO:0051234,GO:0061077,GO:0071702,GO:0071705,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 540.0
CMS2_k127_48482_5 Bacterial extracellular solute-binding protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 513.0
CMS2_k127_48482_6 Binding-protein-dependent transport system inner membrane component K12369 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 495.0
CMS2_k127_48482_7 Binding-protein-dependent transport system inner membrane component K02054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005957 481.0
CMS2_k127_48482_8 N-terminal TM domain of oligopeptide transport permease C K02034,K12370 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 422.0
CMS2_k127_48482_9 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 411.0
CMS2_k127_484835_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1142.0
CMS2_k127_484835_1 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 1.469e-292 911.0
CMS2_k127_484835_10 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 473.0
CMS2_k127_484835_11 Amidohydrolase family K05603 - 3.5.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 463.0
CMS2_k127_484835_12 branched-chain amino acid K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 450.0
CMS2_k127_484835_13 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005567 445.0
CMS2_k127_484835_14 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 408.0
CMS2_k127_484835_15 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 398.0
CMS2_k127_484835_16 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 377.0
CMS2_k127_484835_17 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 377.0
CMS2_k127_484835_18 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007041 373.0
CMS2_k127_484835_19 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 363.0
CMS2_k127_484835_2 COG1138 Cytochrome c biogenesis factor K02198 - - 7.883e-272 851.0
CMS2_k127_484835_20 LysR substrate binding domain K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 338.0
CMS2_k127_484835_21 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 345.0
CMS2_k127_484835_22 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 290.0
CMS2_k127_484835_23 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006885 284.0
CMS2_k127_484835_24 COG4235 Cytochrome c biogenesis factor K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008234 292.0
CMS2_k127_484835_25 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002146 254.0
CMS2_k127_484835_26 Redoxin K02199 - - 0.00000000000000000000000000000000000000000000000000000000000001182 220.0
CMS2_k127_484835_27 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000005604 220.0
CMS2_k127_484835_28 SpoU rRNA Methylase family - - - 0.0000000000000000000000000000000000000000000000000000000000002285 220.0
CMS2_k127_484835_29 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000003472 186.0
CMS2_k127_484835_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 8.333e-194 630.0
CMS2_k127_484835_30 invasion associated locus B - - - 0.000000000000000000000000000000000000002087 152.0
CMS2_k127_484835_32 PAS domain - - - 0.000000000002765 75.0
CMS2_k127_484835_33 - - - - 0.000000000004216 68.0
CMS2_k127_484835_34 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.00000001093 59.0
CMS2_k127_484835_35 Domain of unknown function (DUF1127) - - - 0.00000007699 56.0
CMS2_k127_484835_36 PFAM Mo-dependent nitrogenase - - - 0.0000003558 60.0
CMS2_k127_484835_37 PAS domain - - - 0.000002413 56.0
CMS2_k127_484835_4 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 577.0
CMS2_k127_484835_5 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 529.0
CMS2_k127_484835_6 imidazolonepropionase activity K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 503.0
CMS2_k127_484835_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 503.0
CMS2_k127_484835_8 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 486.0
CMS2_k127_484835_9 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 481.0
CMS2_k127_4887020_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.036e-255 802.0
CMS2_k127_4887020_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 488.0
CMS2_k127_4887020_2 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005549 244.0
CMS2_k127_4887020_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009347 249.0
CMS2_k127_4887020_4 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000189 231.0
CMS2_k127_4887020_5 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000008129 225.0
CMS2_k127_4887020_6 - - - - 0.00000000000000000000000487 103.0
CMS2_k127_4887020_7 PFAM FeoA family protein K04758 - - 0.00000000000000000006567 94.0
CMS2_k127_4887020_8 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000007653 50.0
CMS2_k127_4890206_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 8.007e-249 779.0
CMS2_k127_4890206_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 411.0
CMS2_k127_4890206_10 PFAM helix-turn-helix domain protein - - - 0.0005371 47.0
CMS2_k127_4890206_2 Lytic murein transglycosylase K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 391.0
CMS2_k127_4890206_3 DNA polymerase III subunit delta K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 372.0
CMS2_k127_4890206_4 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 353.0
CMS2_k127_4890206_5 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 305.0
CMS2_k127_4890206_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 290.0
CMS2_k127_4890206_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001365 271.0
CMS2_k127_4890206_8 - - - - 0.000000000000006477 77.0
CMS2_k127_4890206_9 Resolvase, N terminal domain - - - 0.000000001003 61.0
CMS2_k127_4927105_0 oxidoreductase activity K11089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 482.0
CMS2_k127_4927105_1 Membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 336.0
CMS2_k127_4927105_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 318.0
CMS2_k127_4927105_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 306.0
CMS2_k127_4927105_4 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000001046 175.0
CMS2_k127_4927105_5 Cyclophilin-like - - - 0.0000000000001843 78.0
CMS2_k127_4939920_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1112.0
CMS2_k127_4939920_1 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 9.438e-309 959.0
CMS2_k127_4939920_10 Pfam Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 548.0
CMS2_k127_4939920_11 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 448.0
CMS2_k127_4939920_12 Electron transfer flavoprotein K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006687 444.0
CMS2_k127_4939920_13 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 447.0
CMS2_k127_4939920_14 prephenate dehydrogenase K00210,K00220,K04517 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019438,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0047794,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.3.1.12,1.3.1.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 423.0
CMS2_k127_4939920_15 Electron transfer flavoprotein, beta subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 389.0
CMS2_k127_4939920_16 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 386.0
CMS2_k127_4939920_17 cell division K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 337.0
CMS2_k127_4939920_18 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 315.0
CMS2_k127_4939920_19 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 324.0
CMS2_k127_4939920_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001,K14446 - 1.1.1.1,1.3.1.85 7.15e-259 800.0
CMS2_k127_4939920_20 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 307.0
CMS2_k127_4939920_21 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 293.0
CMS2_k127_4939920_22 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 282.0
CMS2_k127_4939920_23 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002163 284.0
CMS2_k127_4939920_24 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001562 231.0
CMS2_k127_4939920_25 Cell division protein K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000005978 235.0
CMS2_k127_4939920_26 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000001338 232.0
CMS2_k127_4939920_27 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000312 231.0
CMS2_k127_4939920_28 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000000000000000008417 228.0
CMS2_k127_4939920_29 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000001019 228.0
CMS2_k127_4939920_3 COG1960 Acyl-CoA dehydrogenases K14448 - 1.3.8.12 1.157e-247 774.0
CMS2_k127_4939920_30 chorismate mutase - - - 0.00000000000000000000000000000000000000000000000000000000000002253 224.0
CMS2_k127_4939920_31 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000003889 211.0
CMS2_k127_4939920_32 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000006067 208.0
CMS2_k127_4939920_33 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000004608 196.0
CMS2_k127_4939920_34 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000000009281 175.0
CMS2_k127_4939920_35 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000147 175.0
CMS2_k127_4939920_36 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000025 136.0
CMS2_k127_4939920_37 - - - - 0.00000000000000000000000000001453 128.0
CMS2_k127_4939920_38 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000002806 121.0
CMS2_k127_4939920_39 of the double-stranded beta helix - - - 0.0000000000000000000000000006179 123.0
CMS2_k127_4939920_4 argininosuccinate lyase K01755 - 4.3.2.1 1.379e-205 649.0
CMS2_k127_4939920_40 bond formation protein, DsbB - - - 0.0000000000000000000000001514 111.0
CMS2_k127_4939920_41 YCII-related domain K09780 - - 0.0000000000000000000000004888 110.0
CMS2_k127_4939920_42 - - - - 0.00000000000000000001468 94.0
CMS2_k127_4939920_43 Hypoxia induced protein conserved region - - - 0.0000000001758 66.0
CMS2_k127_4939920_44 Protein of unknown function (DUF3426) - - - 0.00000001106 64.0
CMS2_k127_4939920_45 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.0000003915 55.0
CMS2_k127_4939920_5 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 3.302e-202 634.0
CMS2_k127_4939920_6 Domain of unknown function (DUF4175) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 627.0
CMS2_k127_4939920_7 component I K01665,K03342 - 2.6.1.85,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 578.0
CMS2_k127_4939920_8 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01907 - 6.2.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 564.0
CMS2_k127_4939920_9 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 550.0
CMS2_k127_49608_0 Function of homologous gene experimentally demonstrated in an other organism K03407 - 2.7.13.3 1.81e-273 869.0
CMS2_k127_49608_1 signal transduction histidine kinase K13587 - 2.7.13.3 1.111e-194 635.0
CMS2_k127_49608_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 294.0
CMS2_k127_49608_11 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000005604 220.0
CMS2_k127_49608_12 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000007639 212.0
CMS2_k127_49608_13 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000009076 213.0
CMS2_k127_49608_14 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000001525 201.0
CMS2_k127_49608_15 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000009261 171.0
CMS2_k127_49608_16 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000002122 145.0
CMS2_k127_49608_17 SnoaL-like domain - - - 0.0000000000000000000000000000000000002929 144.0
CMS2_k127_49608_18 Histidine phosphotransferase C-terminal domain K13588 - - 0.000000000000000000000000000000000001122 146.0
CMS2_k127_49608_19 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000008364 140.0
CMS2_k127_49608_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 536.0
CMS2_k127_49608_20 COG2199 FOG GGDEF domain K13069 - 2.7.7.65 0.0000000000000000000000000000002945 135.0
CMS2_k127_49608_21 Protein of unknown function (DUF1153) - - - 0.000000000000000000000000000001192 122.0
CMS2_k127_49608_22 Endoribonuclease L-PSP - - - 0.000000000000000000000000102 116.0
CMS2_k127_49608_23 - - - - 0.000000000000000001844 88.0
CMS2_k127_49608_24 Protein of unknown function (DUF3553) - - - 0.000000000000001809 79.0
CMS2_k127_49608_25 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.000000000009533 74.0
CMS2_k127_49608_26 diguanylate cyclase activity - - - 0.0000000000276 71.0
CMS2_k127_49608_27 response regulator containing a CheY-like receiver domain and a GGDEF domain K13069 - 2.7.7.65 0.00000000491 64.0
CMS2_k127_49608_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 467.0
CMS2_k127_49608_4 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 441.0
CMS2_k127_49608_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 408.0
CMS2_k127_49608_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K13584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 392.0
CMS2_k127_49608_7 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 339.0
CMS2_k127_49608_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 344.0
CMS2_k127_49608_9 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 320.0
CMS2_k127_50055_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0 1092.0
CMS2_k127_50055_1 Belongs to the TPP enzyme family K03852 - 2.3.3.15 0.0 1039.0
CMS2_k127_50055_10 deoxyribose-phosphate aldolase activity K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 491.0
CMS2_k127_50055_11 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 486.0
CMS2_k127_50055_12 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 501.0
CMS2_k127_50055_13 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 457.0
CMS2_k127_50055_14 FAD dependent oxidoreductase K00244 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 450.0
CMS2_k127_50055_15 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 370.0
CMS2_k127_50055_16 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 351.0
CMS2_k127_50055_17 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 316.0
CMS2_k127_50055_18 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 303.0
CMS2_k127_50055_19 Putative sugar-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 300.0
CMS2_k127_50055_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 3.359e-205 648.0
CMS2_k127_50055_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 297.0
CMS2_k127_50055_21 CorA-like Mg2+ transporter protein K16074 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002628 279.0
CMS2_k127_50055_22 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002913 273.0
CMS2_k127_50055_23 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001916 267.0
CMS2_k127_50055_24 KR domain K21883 - 1.1.1.401 0.0000000000000000000000000000000000000000000000000000000000000000000000000007303 262.0
CMS2_k127_50055_25 Domain of unknown function (DUF4202) - - - 0.00000000000000000000000000000000000000000000000000000000000005954 219.0
CMS2_k127_50055_26 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000007113 174.0
CMS2_k127_50055_27 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.000000000000000000000000000000000000000000000963 176.0
CMS2_k127_50055_28 N-terminal domain of cytochrome oxidase-cbb3, FixP K00406 - - 0.0007338 47.0
CMS2_k127_50055_3 transport systems, ATPase components K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 613.0
CMS2_k127_50055_4 Belongs to the 5'-nucleotidase family K01081,K11751 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 531.0
CMS2_k127_50055_5 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009337 527.0
CMS2_k127_50055_6 Metalloenzyme superfamily K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 530.0
CMS2_k127_50055_7 TatD related DNase K07051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 504.0
CMS2_k127_50055_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 501.0
CMS2_k127_50055_9 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005342 496.0
CMS2_k127_5021555_0 PFAM type III effector Hrp-dependent outers K21948 - 2.7.1.217 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 569.0
CMS2_k127_5021555_1 Dehydrogenase K08319 - 1.1.1.411 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 349.0
CMS2_k127_5021555_2 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K01826 - 5.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 332.0
CMS2_k127_5034148_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.94e-281 883.0
CMS2_k127_5034148_1 single-stranded-DNA-specific exonuclease recJ K07462 - - 5.741e-230 728.0
CMS2_k127_5034148_2 Aminotransferase K14261 - - 1.347e-207 651.0
CMS2_k127_5034148_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 602.0
CMS2_k127_5034148_4 homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 570.0
CMS2_k127_5034148_5 COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins K11532 - 3.1.3.11,3.1.3.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 472.0
CMS2_k127_5034148_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 363.0
CMS2_k127_5034148_7 COG2346, Truncated hemoglobins K03406,K06886 GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057 - 0.0000000000000000000000000000008555 136.0
CMS2_k127_5034148_8 Beta-lactamase superfamily domain - - - 0.000000000000000000001882 101.0
CMS2_k127_5034148_9 - - - - 0.00000001716 58.0
CMS2_k127_5041038_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 434.0
CMS2_k127_5058847_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1365.0
CMS2_k127_5058847_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 4.395e-303 943.0
CMS2_k127_5058847_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 3.013e-217 681.0
CMS2_k127_5058847_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 404.0
CMS2_k127_5058847_4 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 306.0
CMS2_k127_5058847_5 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000008048 231.0
CMS2_k127_5058847_6 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000007194 216.0
CMS2_k127_5058847_7 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000006013 203.0
CMS2_k127_5058847_8 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 - 2.7.7.65 0.0000000000000000000000000000000005772 147.0
CMS2_k127_5058847_9 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000000000000001566 106.0
CMS2_k127_5074609_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 521.0
CMS2_k127_5074609_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 399.0
CMS2_k127_5074609_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 331.0
CMS2_k127_5074609_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 320.0
CMS2_k127_5074609_4 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000001779 208.0
CMS2_k127_5074609_5 peptidase - - - 0.0003061 43.0
CMS2_k127_5075964_0 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 372.0
CMS2_k127_5075964_1 MatE K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000005675 248.0
CMS2_k127_5075964_2 dioxygenase of extradiol dioxygenase family K06991 - - 0.00000000000000000000000000000000000000000000000000000281 192.0
CMS2_k127_5075964_3 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000218 170.0
CMS2_k127_5075964_4 OsmC-like protein - - - 0.0000006516 51.0
CMS2_k127_5126890_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 9.089e-297 932.0
CMS2_k127_5126890_1 Seven times multi-haem cytochrome CxxCH K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 600.0
CMS2_k127_5126890_2 Ureidoglycolate lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 388.0
CMS2_k127_5126890_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000001282 233.0
CMS2_k127_5148245_0 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 3.535e-205 649.0
CMS2_k127_5148245_1 ABC transporter K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 519.0
CMS2_k127_5148245_2 Gluconolactonase K01053,K14274 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 444.0
CMS2_k127_5148245_3 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 422.0
CMS2_k127_5148245_4 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 412.0
CMS2_k127_5148245_5 COG0524 Sugar kinases, ribokinase family K00874 - 2.7.1.45 0.00000000000000000000001685 104.0
CMS2_k127_5148245_6 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000005438 59.0
CMS2_k127_5152500_0 malic enzyme K00029 - 1.1.1.40 0.0 1042.0
CMS2_k127_5152500_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009522 576.0
CMS2_k127_5152500_2 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 489.0
CMS2_k127_5152500_3 ABC-type histidine transport system, ATPase component K02028,K10025 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 388.0
CMS2_k127_5152500_4 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 381.0
CMS2_k127_5152500_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 307.0
CMS2_k127_5152500_6 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004303 264.0
CMS2_k127_5177801_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 459.0
CMS2_k127_5177801_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 389.0
CMS2_k127_5177801_2 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0008326 44.0
CMS2_k127_5184144_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 8.652e-233 726.0
CMS2_k127_5184144_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.066e-195 620.0
CMS2_k127_5184144_10 overlaps another CDS with the same product name K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 413.0
CMS2_k127_5184144_11 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K10831 - 3.6.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 367.0
CMS2_k127_5184144_12 overlaps another CDS with the same product name K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 362.0
CMS2_k127_5184144_13 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 315.0
CMS2_k127_5184144_14 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 295.0
CMS2_k127_5184144_15 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007691 294.0
CMS2_k127_5184144_16 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001686 280.0
CMS2_k127_5184144_17 Helix-turn-helix domain, rpiR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002843 274.0
CMS2_k127_5184144_18 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001262 248.0
CMS2_k127_5184144_19 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000001633 216.0
CMS2_k127_5184144_2 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 574.0
CMS2_k127_5184144_20 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000121 206.0
CMS2_k127_5184144_21 Involved in biosynthesis of extracellular polysaccharides - - - 0.00000000000000000000000000000000000000000002014 169.0
CMS2_k127_5184144_22 PFAM VanZ - - - 0.0000000003953 66.0
CMS2_k127_5184144_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 556.0
CMS2_k127_5184144_4 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 536.0
CMS2_k127_5184144_5 COG3842 ABC-type spermidine putrescine transport systems, ATPase components K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 519.0
CMS2_k127_5184144_6 Na phosphate symporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 524.0
CMS2_k127_5184144_7 taurine ABC transporter K15551 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 449.0
CMS2_k127_5184144_8 phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 437.0
CMS2_k127_5184144_9 ABC-type nitrate sulfonate bicarbonate transport system permease component K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 427.0
CMS2_k127_5187965_0 D-galactarate dehydratase / Altronate hydrolase, C terminus - - - 1.62e-239 753.0
CMS2_k127_5187965_1 gluconolactonase K01053,K14274 GO:0003674,GO:0003824,GO:0004341,GO:0016787,GO:0016788,GO:0052689 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 386.0
CMS2_k127_5187965_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 336.0
CMS2_k127_5191673_0 DNA polymerase K02337 - 2.7.7.7 0.0 1416.0
CMS2_k127_5191673_1 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.11e-290 902.0
CMS2_k127_5191673_10 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000001708 156.0
CMS2_k127_5191673_11 ThiS family - - - 0.0000000000000000005258 92.0
CMS2_k127_5191673_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.873e-210 662.0
CMS2_k127_5191673_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 454.0
CMS2_k127_5191673_4 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 415.0
CMS2_k127_5191673_5 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 312.0
CMS2_k127_5191673_6 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 285.0
CMS2_k127_5191673_7 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008359 260.0
CMS2_k127_5191673_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05796 - - 0.00000000000000000000000000000000000000000000000000000000000000002576 226.0
CMS2_k127_5191673_9 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000003462 173.0
CMS2_k127_5213984_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 587.0
CMS2_k127_5213984_1 Methylenetetrahydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 501.0
CMS2_k127_5213984_10 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000000000000000000007954 153.0
CMS2_k127_5213984_11 Thioesterase - - - 0.00004098 46.0
CMS2_k127_5213984_2 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 421.0
CMS2_k127_5213984_3 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 395.0
CMS2_k127_5213984_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 351.0
CMS2_k127_5213984_5 Uncharacterized protein family (UPF0051) K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007042 246.0
CMS2_k127_5213984_6 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000002935 232.0
CMS2_k127_5213984_7 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000008758 215.0
CMS2_k127_5213984_8 Ferredoxin K04755 - - 0.0000000000000000000000000000000000000000000000005641 177.0
CMS2_k127_5213984_9 Iron-sulfur cluster assembly protein - - - 0.00000000000000000000000000000000000000000005643 166.0
CMS2_k127_5276192_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1020.0
CMS2_k127_5276192_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.271e-315 976.0
CMS2_k127_5276192_10 Auxin binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 310.0
CMS2_k127_5276192_11 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 320.0
CMS2_k127_5276192_12 membrane K08978,K12962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 293.0
CMS2_k127_5276192_13 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007044 285.0
CMS2_k127_5276192_14 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006665 257.0
CMS2_k127_5276192_15 response to stress - - - 0.00000000000000000000000000000000000000000000000000000000000000002018 234.0
CMS2_k127_5276192_16 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000007179 228.0
CMS2_k127_5276192_17 DnaJ-class molecular chaperone - - - 0.000000000000000000000000000000000000000000000000000000001961 209.0
CMS2_k127_5276192_18 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000005241 197.0
CMS2_k127_5276192_19 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000000000000000007177 188.0
CMS2_k127_5276192_2 Tripartite tricarboxylate transporter TctA family - - - 6.59e-256 808.0
CMS2_k127_5276192_20 endoribonuclease L-PSP - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000007711 178.0
CMS2_k127_5276192_21 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000006125 177.0
CMS2_k127_5276192_22 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000003665 87.0
CMS2_k127_5276192_23 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000002885 81.0
CMS2_k127_5276192_24 Recombinase zinc beta ribbon domain - - - 0.00000000001937 64.0
CMS2_k127_5276192_3 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K15738 - - 1.657e-216 687.0
CMS2_k127_5276192_4 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 555.0
CMS2_k127_5276192_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 540.0
CMS2_k127_5276192_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 357.0
CMS2_k127_5276192_7 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 320.0
CMS2_k127_5276192_8 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 317.0
CMS2_k127_5276192_9 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 314.0
CMS2_k127_5279299_0 NADH:flavin oxidoreductase / NADH oxidase family K00317 - 1.5.8.1,1.5.8.2 0.0 1106.0
CMS2_k127_5279299_1 belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 1.619e-248 783.0
CMS2_k127_5279299_10 bleomycin resistance protein K01759 - 4.4.1.5 0.0000000000000000000000000000000000000004399 151.0
CMS2_k127_5279299_11 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K21395 - - 0.00000000000000000000000000000000000002884 149.0
CMS2_k127_5279299_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 3.055e-223 716.0
CMS2_k127_5279299_3 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 4.809e-211 670.0
CMS2_k127_5279299_4 MlrC C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 561.0
CMS2_k127_5279299_5 LysR substrate binding domain K21645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 389.0
CMS2_k127_5279299_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004008 255.0
CMS2_k127_5279299_7 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000005233 185.0
CMS2_k127_5279299_8 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K03519,K18021 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.5.3,1.2.99.8 0.00000000000000000000000000000000000000000000005837 180.0
CMS2_k127_5279299_9 Hydantoinase B/oxoprolinase - - - 0.00000000000000000000000000000000000000000001815 164.0
CMS2_k127_5347530_0 Belongs to the IlvD Edd family K13875 - 4.2.1.25 6.929e-294 909.0
CMS2_k127_5347530_1 ABC-type sugar transport system periplasmic component K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 485.0
CMS2_k127_5347530_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008812 362.0
CMS2_k127_5347530_3 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000132 228.0
CMS2_k127_5505924_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 7.662e-230 716.0
CMS2_k127_5505924_1 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 592.0
CMS2_k127_5505924_10 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000005656 160.0
CMS2_k127_5505924_11 Membrane transport protein K07088 - - 0.0000000000000000000000000003016 118.0
CMS2_k127_5505924_12 PIN domain - - - 0.000000000000000000000003103 109.0
CMS2_k127_5505924_13 PA14 domain - - - 0.00000000000000000519 93.0
CMS2_k127_5505924_14 Small membrane protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000002597 89.0
CMS2_k127_5505924_16 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000009537 55.0
CMS2_k127_5505924_17 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000001446 53.0
CMS2_k127_5505924_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 520.0
CMS2_k127_5505924_3 TIGRFAM ATP phosphoribosyltransferase, C-terminal domain K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 396.0
CMS2_k127_5505924_4 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 321.0
CMS2_k127_5505924_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001679 239.0
CMS2_k127_5505924_6 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000004164 214.0
CMS2_k127_5505924_7 - - - - 0.000000000000000000000000000000000000000000000000000000007732 207.0
CMS2_k127_5505924_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000006652 202.0
CMS2_k127_5505924_9 NAD(P)H-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000002417 182.0
CMS2_k127_5512713_0 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000001789 189.0
CMS2_k127_5512713_1 Pilus assembly protein CpaB K02279 - - 0.000000000000000000000000000000000000000002244 166.0
CMS2_k127_5512713_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000001245 118.0
CMS2_k127_5512713_3 Dehydrogenase - - - 0.0000000000000004244 91.0
CMS2_k127_5512713_4 Type IV leader peptidase family K02278 - 3.4.23.43 0.0000000004769 67.0
CMS2_k127_5512713_5 Flp Fap pilin component K02651 - - 0.000000002194 60.0
CMS2_k127_5512713_6 Flp Fap pilin component K02651 - - 0.000000006902 59.0
CMS2_k127_5512713_7 Flp pilus assembly protein, pilin Flp K02651 - - 0.00000002759 59.0
CMS2_k127_5512713_8 Flp pilus assembly protein, pilin Flp K02651 - - 0.0000007898 56.0
CMS2_k127_5512713_9 GGDEF domain - - - 0.0001096 56.0
CMS2_k127_5518659_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0 1055.0
CMS2_k127_5518659_1 ABC-type dipeptide transport system periplasmic component K02035 - - 8.232e-231 726.0
CMS2_k127_5518659_10 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 417.0
CMS2_k127_5518659_11 COG1176 ABC-type spermidine putrescine transport system permease component I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 375.0
CMS2_k127_5518659_12 Binding-protein-dependent transport system inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 356.0
CMS2_k127_5518659_13 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001215 282.0
CMS2_k127_5518659_14 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000001212 156.0
CMS2_k127_5518659_15 Belongs to the GcvT family K00315 - 1.5.8.4 0.00000000000000007073 80.0
CMS2_k127_5518659_2 Belongs to the thiolase family K00626,K00632,K07823 - 2.3.1.16,2.3.1.174,2.3.1.9 3.927e-211 661.0
CMS2_k127_5518659_3 FAD dependent oxidoreductase - - - 1.955e-195 619.0
CMS2_k127_5518659_4 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 530.0
CMS2_k127_5518659_5 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 529.0
CMS2_k127_5518659_6 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 479.0
CMS2_k127_5518659_7 Adenylosuccinate lyase C-terminus K01756,K01857 - 4.3.2.2,5.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 471.0
CMS2_k127_5518659_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 449.0
CMS2_k127_5518659_9 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008636 443.0
CMS2_k127_5582721_0 AAA domain - - - 3.108e-284 895.0
CMS2_k127_5582721_1 FIST_C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 360.0
CMS2_k127_5582721_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000001096 188.0
CMS2_k127_5582721_11 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000001619 186.0
CMS2_k127_5582721_12 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000001756 181.0
CMS2_k127_5582721_13 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000002998 164.0
CMS2_k127_5582721_14 Beta-lactamase - - - 0.00000000000000000000000000006645 117.0
CMS2_k127_5582721_15 PFAM Protein kinase domain - - - 0.00000000067 71.0
CMS2_k127_5582721_16 PFAM Protein kinase domain - - - 0.00000001783 67.0
CMS2_k127_5582721_17 Putative peptidoglycan binding domain K07126,K13582 - - 0.00000007535 64.0
CMS2_k127_5582721_18 Putative peptidoglycan binding domain - - - 0.000001152 61.0
CMS2_k127_5582721_2 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 342.0
CMS2_k127_5582721_3 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 336.0
CMS2_k127_5582721_4 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 315.0
CMS2_k127_5582721_5 Uracil-DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 301.0
CMS2_k127_5582721_6 transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002211 277.0
CMS2_k127_5582721_7 transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001057 271.0
CMS2_k127_5582721_8 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000001759 243.0
CMS2_k127_5582721_9 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000008252 210.0
CMS2_k127_5639761_0 COG1924 Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) - - - 0.0 1520.0
CMS2_k127_5639761_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 5.6e-322 997.0
CMS2_k127_5639761_10 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 547.0
CMS2_k127_5639761_11 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008634 526.0
CMS2_k127_5639761_12 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 518.0
CMS2_k127_5639761_13 ABC transporter K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 508.0
CMS2_k127_5639761_14 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K09969 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 495.0
CMS2_k127_5639761_15 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 482.0
CMS2_k127_5639761_16 Binding-protein-dependent transport system inner membrane component K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008626 467.0
CMS2_k127_5639761_17 ABC-type polar amino acid transport system ATPase component K02028,K09972 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 448.0
CMS2_k127_5639761_18 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005497 430.0
CMS2_k127_5639761_19 amino acid ABC transporter K02029,K09971,K10002,K10037 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 419.0
CMS2_k127_5639761_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 9.395e-295 917.0
CMS2_k127_5639761_20 Amino-transferase class IV K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007467 377.0
CMS2_k127_5639761_21 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 360.0
CMS2_k127_5639761_22 Short-chain dehydrogenase reductase SDR K21883 - 1.1.1.401 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005916 349.0
CMS2_k127_5639761_23 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 353.0
CMS2_k127_5639761_24 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 351.0
CMS2_k127_5639761_25 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 333.0
CMS2_k127_5639761_26 COG0811 Biopolymer transport proteins K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 320.0
CMS2_k127_5639761_27 ADP-glyceromanno-heptose 6-epimerase activity K01709,K22025 - 1.1.1.410,4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 322.0
CMS2_k127_5639761_28 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 318.0
CMS2_k127_5639761_29 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 315.0
CMS2_k127_5639761_3 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 5.729e-287 915.0
CMS2_k127_5639761_30 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 291.0
CMS2_k127_5639761_31 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 293.0
CMS2_k127_5639761_32 Methyltransferase domain - GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0030312,GO:0032259,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 300.0
CMS2_k127_5639761_33 methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 306.0
CMS2_k127_5639761_34 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006847 282.0
CMS2_k127_5639761_35 sugar phosphatases of the HAD superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006848 281.0
CMS2_k127_5639761_36 Phenazine biosynthesis-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000678 263.0
CMS2_k127_5639761_37 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.00000000000000000000000000000000000000000000000000000000000000000000016 250.0
CMS2_k127_5639761_38 Fumarylacetoacetate (FAA) hydrolase family K01617 - 4.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000008611 246.0
CMS2_k127_5639761_39 sugar phosphatases of the HAD superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000001264 242.0
CMS2_k127_5639761_4 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 1.675e-221 692.0
CMS2_k127_5639761_40 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000001436 225.0
CMS2_k127_5639761_41 KDPG and KHG aldolase K01631 - 4.1.2.21 0.0000000000000000000000000000000000000000000000000000000000000002152 226.0
CMS2_k127_5639761_42 SOS response associated peptidase (SRAP) - - - 0.0000000000000000000000000000000000000000000000000000000000000005267 229.0
CMS2_k127_5639761_43 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000684 228.0
CMS2_k127_5639761_44 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000009907 223.0
CMS2_k127_5639761_45 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000002101 216.0
CMS2_k127_5639761_46 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000001601 203.0
CMS2_k127_5639761_47 methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000001153 199.0
CMS2_k127_5639761_48 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000023 186.0
CMS2_k127_5639761_49 Biopolymer transport protein K03559,K03560 - - 0.0000000000000000000000000000000000000000000000005983 178.0
CMS2_k127_5639761_5 Involved in the TonB-independent uptake of proteins K03641 - - 4.384e-210 661.0
CMS2_k127_5639761_50 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000001804 181.0
CMS2_k127_5639761_51 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000004619 164.0
CMS2_k127_5639761_52 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000237 153.0
CMS2_k127_5639761_53 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000768 145.0
CMS2_k127_5639761_54 Cell division and transport-associated protein TolA K03646 - - 0.0000000000000000000000000000000003105 143.0
CMS2_k127_5639761_55 Putative diguanylate phosphodiesterase K13593 - - 0.0000000000000000000000000000000003829 149.0
CMS2_k127_5639761_56 thioesterase K07107 - - 0.00000000000000000000000000000002745 131.0
CMS2_k127_5639761_57 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000001932 137.0
CMS2_k127_5639761_58 ParB-like nuclease domain - - - 0.000000000000000000008964 94.0
CMS2_k127_5639761_6 TRAP-type C4-dicarboxylate transport system, large permease component - - - 2.501e-197 622.0
CMS2_k127_5639761_60 Response regulator receiver - - - 0.0000000002756 68.0
CMS2_k127_5639761_63 HNH endonuclease - - - 0.0002368 47.0
CMS2_k127_5639761_7 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 4.754e-195 618.0
CMS2_k127_5639761_8 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 606.0
CMS2_k127_5639761_9 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 556.0
CMS2_k127_5657471_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.3e-214 677.0
CMS2_k127_5657471_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 586.0
CMS2_k127_5657471_10 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000001154 218.0
CMS2_k127_5657471_11 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000000000008601 198.0
CMS2_k127_5657471_12 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.00000000000000000000000000000000000000000000000000002497 205.0
CMS2_k127_5657471_13 ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000000001835 173.0
CMS2_k127_5657471_14 - - - - 0.0009163 43.0
CMS2_k127_5657471_2 Amidohydrolase K10220 - 4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 541.0
CMS2_k127_5657471_3 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K20940 - 1.14.13.218 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 485.0
CMS2_k127_5657471_4 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K21826 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 392.0
CMS2_k127_5657471_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 308.0
CMS2_k127_5657471_6 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 299.0
CMS2_k127_5657471_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008385 275.0
CMS2_k127_5657471_8 COG1145 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004737 252.0
CMS2_k127_5657471_9 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000001365 234.0
CMS2_k127_5694978_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 615.0
CMS2_k127_5694978_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 589.0
CMS2_k127_5694978_2 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 521.0
CMS2_k127_5694978_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 469.0
CMS2_k127_5694978_4 Phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.000000000000000000000000000000000004856 144.0
CMS2_k127_5694978_6 Trypsin-like serine protease - - - 0.00000000002275 75.0
CMS2_k127_5708813_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 609.0
CMS2_k127_5708813_1 COG1012 NAD-dependent aldehyde dehydrogenases K21802 - 1.2.1.67 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 563.0
CMS2_k127_5708813_2 FMN-dependent dehydrogenase K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009268 302.0
CMS2_k127_5708813_3 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000523 142.0
CMS2_k127_5708813_4 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0005809 42.0
CMS2_k127_5716895_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K00249,K00294,K13821 - 1.2.1.88,1.3.8.7,1.5.5.2 0.0 1246.0
CMS2_k127_5716895_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 3.439e-240 752.0
CMS2_k127_5716895_10 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 390.0
CMS2_k127_5716895_11 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 341.0
CMS2_k127_5716895_12 membrane transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000146 258.0
CMS2_k127_5716895_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001369 245.0
CMS2_k127_5716895_14 ABC transporter K02074 - - 0.00000000000000000000000000000000000000000000000000000000000000002118 233.0
CMS2_k127_5716895_15 Belongs to the bacterial solute-binding protein 9 family K02077 - - 0.0000000000000000000000000000000000000000000000000000000001584 226.0
CMS2_k127_5716895_16 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000002269 190.0
CMS2_k127_5716895_17 Regulatory protein ArsR - - - 0.0000000000000000000000000000006359 125.0
CMS2_k127_5716895_18 COG3239 Fatty acid desaturase - - - 0.0000000000000000000000000000016 132.0
CMS2_k127_5716895_19 dioxygenase of extradiol dioxygenase family K06991 - - 0.000000000000000000002878 94.0
CMS2_k127_5716895_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 8.147e-212 664.0
CMS2_k127_5716895_20 TPR repeat - - - 0.0000000000000005389 90.0
CMS2_k127_5716895_3 TrkA-C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 618.0
CMS2_k127_5716895_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 578.0
CMS2_k127_5716895_5 Isocitrate/isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 551.0
CMS2_k127_5716895_6 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 488.0
CMS2_k127_5716895_7 Adenylate cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 488.0
CMS2_k127_5716895_8 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 437.0
CMS2_k127_5716895_9 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 404.0
CMS2_k127_5725954_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1573.0
CMS2_k127_5725954_1 oligoendopeptidase F K08602 - - 1.052e-273 854.0
CMS2_k127_5725954_2 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 6.596e-225 711.0
CMS2_k127_5725954_3 ABC1 family - - - 3.912e-202 637.0
CMS2_k127_5725954_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002423 217.0
CMS2_k127_5725954_5 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000005204 208.0
CMS2_k127_5725954_6 Suppressor of fused protein (SUFU) - - - 0.0000000000000000000000000000000000000001733 157.0
CMS2_k127_5725954_7 BON domain - - - 0.000000000000005949 84.0
CMS2_k127_5746751_0 Cytochrome c bacterial - - - 5.815e-217 689.0
CMS2_k127_5746751_1 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 614.0
CMS2_k127_5746751_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000001212 228.0
CMS2_k127_5746751_11 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000009765 186.0
CMS2_k127_5746751_12 Cold shock protein domain K03704 - - 0.0000000000000000000000000008549 114.0
CMS2_k127_5746751_13 Protein of unknown function (DUF1449) - - - 0.000000000000003447 76.0
CMS2_k127_5746751_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 610.0
CMS2_k127_5746751_3 DNA helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 556.0
CMS2_k127_5746751_4 Zn-dependent alcohol dehydrogenases K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 451.0
CMS2_k127_5746751_5 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006721 394.0
CMS2_k127_5746751_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 386.0
CMS2_k127_5746751_7 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 382.0
CMS2_k127_5746751_8 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 296.0
CMS2_k127_5746751_9 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001304 250.0
CMS2_k127_5783785_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 1.989e-228 721.0
CMS2_k127_5783785_1 belongs to the aldehyde dehydrogenase family - - - 1.815e-221 694.0
CMS2_k127_5783785_10 peptidase activity, acting on L-amino acid peptides - - - 0.00006316 54.0
CMS2_k127_5783785_2 COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 617.0
CMS2_k127_5783785_3 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 565.0
CMS2_k127_5783785_4 COG2113 ABC-type proline glycine betaine transport systems periplasmic components K02002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 501.0
CMS2_k127_5783785_5 ATPases associated with a variety of cellular activities K02000 - 3.6.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005554 488.0
CMS2_k127_5783785_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 307.0
CMS2_k127_5783785_7 DeoR C terminal sensor domain K02444 - - 0.000000000000000000000000000000000000000000000000000000000001223 219.0
CMS2_k127_5783785_8 lipopolysaccharide transport K09774 - - 0.000000000000000001826 93.0
CMS2_k127_5783785_9 Binding-protein-dependent transport system inner membrane component K02001 - - 0.000000000000000002939 88.0
CMS2_k127_5784472_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1099.0
CMS2_k127_5784472_1 Asparagine synthase K01953 - 6.3.5.4 1.733e-275 859.0
CMS2_k127_5784472_10 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 423.0
CMS2_k127_5784472_11 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 334.0
CMS2_k127_5784472_12 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 309.0
CMS2_k127_5784472_13 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 287.0
CMS2_k127_5784472_14 Protein of unknown function (DUF1194) - - - 0.000000000000000000000000000000000000000000000000000000000000000000057 241.0
CMS2_k127_5784472_15 Protein of unknown function (DUF1194) - - - 0.000000000000000000000000000000000000000000000000000000000000002334 226.0
CMS2_k127_5784472_16 - K09957 - - 0.0000000000000000000000000000000000000004924 156.0
CMS2_k127_5784472_17 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000175 128.0
CMS2_k127_5784472_19 Domain of unknown function (DUF1476) - - - 0.0000000000000000000000000001747 119.0
CMS2_k127_5784472_2 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 1.058e-235 737.0
CMS2_k127_5784472_20 BolA-like protein - - - 0.000000000000000003267 84.0
CMS2_k127_5784472_21 Trypsin-like peptidase domain - - - 0.000001919 51.0
CMS2_k127_5784472_22 - - - - 0.0000076 51.0
CMS2_k127_5784472_3 FR47-like protein - - - 6.887e-225 713.0
CMS2_k127_5784472_4 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 6.909e-225 712.0
CMS2_k127_5784472_5 III protein, CoA-transferase family K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 538.0
CMS2_k127_5784472_6 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 515.0
CMS2_k127_5784472_7 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 501.0
CMS2_k127_5784472_8 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 489.0
CMS2_k127_5784472_9 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 453.0
CMS2_k127_5839678_0 ABC-type Fe3 transport system permease component K02011 - - 7.314e-260 816.0
CMS2_k127_5839678_1 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 604.0
CMS2_k127_5839678_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008113 512.0
CMS2_k127_5839678_3 ATPases associated with a variety of cellular activities K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 451.0
CMS2_k127_5839678_4 Phosphonate ABC transporter, permease protein PhnE K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 430.0
CMS2_k127_5839678_5 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 425.0
CMS2_k127_5839678_6 Binding-protein-dependent transport system inner membrane component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 361.0
CMS2_k127_5839678_7 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000188 234.0
CMS2_k127_5839678_8 DNA methylase - - - 0.000000000000000000000000000000000000000000000000000041 194.0
CMS2_k127_5839678_9 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000007599 68.0
CMS2_k127_587636_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1049.0
CMS2_k127_587636_1 Sulfite reductase K00381 - 1.8.1.2 1.289e-241 757.0
CMS2_k127_587636_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000009002 202.0
CMS2_k127_587636_11 helix_turn_helix ASNC type K05800 - - 0.000000000000000000000000000000000000000000000000003917 186.0
CMS2_k127_587636_12 Bacterial protein of unknown function (DUF934) - - - 0.00000000000000000000000000007104 122.0
CMS2_k127_587636_13 DsrE/DsrF-like family K06039,K07092 - - 0.000000000000000000000005111 106.0
CMS2_k127_587636_14 Outer membrane lipoprotein K06077 - - 0.0000000000001601 78.0
CMS2_k127_587636_15 Putative zinc-finger - - - 0.000000000003279 70.0
CMS2_k127_587636_16 Protein of unknown function (DUF2849) - - - 0.000000000005922 70.0
CMS2_k127_587636_17 Outer membrane protein beta-barrel domain - - - 0.0002133 52.0
CMS2_k127_587636_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 339.0
CMS2_k127_587636_3 ( 3 oxidation state) methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 329.0
CMS2_k127_587636_4 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 312.0
CMS2_k127_587636_5 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 313.0
CMS2_k127_587636_6 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001725 261.0
CMS2_k127_587636_7 Domain of unknown function (DUF1287) K09974 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001206 253.0
CMS2_k127_587636_8 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000523 256.0
CMS2_k127_587636_9 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000002096 206.0
CMS2_k127_5883664_0 Alpha-2-Macroglobulin K06894 - - 0.0 1247.0
CMS2_k127_5883664_1 AcrB/AcrD/AcrF family - - - 0.0 1087.0
CMS2_k127_5883664_10 Branched-chain amino acid transport system permease K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007984 454.0
CMS2_k127_5883664_11 Branched-chain amino acid transport K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 411.0
CMS2_k127_5883664_12 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 402.0
CMS2_k127_5883664_13 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 362.0
CMS2_k127_5883664_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 349.0
CMS2_k127_5883664_15 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009582 330.0
CMS2_k127_5883664_16 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 322.0
CMS2_k127_5883664_17 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001978 252.0
CMS2_k127_5883664_18 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007103 251.0
CMS2_k127_5883664_19 Prolyl oligopeptidase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000004452 232.0
CMS2_k127_5883664_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 2.928e-223 707.0
CMS2_k127_5883664_20 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000009629 231.0
CMS2_k127_5883664_21 pilus organization K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000829 209.0
CMS2_k127_5883664_22 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000003593 172.0
CMS2_k127_5883664_23 - - - - 0.0000000000000000000000000000000000000000005226 164.0
CMS2_k127_5883664_24 XdhC and CoxI family - - - 0.0000000000000000000000000000000000000000005888 160.0
CMS2_k127_5883664_25 COG0822 NifU homolog involved in Fe-S cluster formation - - - 0.0000000000000000000000000000001092 136.0
CMS2_k127_5883664_26 - - - - 0.0000000000000000000000000000002327 128.0
CMS2_k127_5883664_27 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0000000000000000000000000001045 128.0
CMS2_k127_5883664_28 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0000000000000000000000001486 120.0
CMS2_k127_5883664_29 Protein conserved in bacteria - - - 0.00000000000000000000004311 108.0
CMS2_k127_5883664_3 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 6.443e-223 711.0
CMS2_k127_5883664_30 SCP-2 sterol transfer family - - - 0.0000000000000000000002297 99.0
CMS2_k127_5883664_31 - - - - 0.000000000000000000321 93.0
CMS2_k127_5883664_32 Universal stress protein family - - - 0.0000000000000000005476 95.0
CMS2_k127_5883664_33 Domain of unknown function (DUF4402) - - - 0.00000000003913 70.0
CMS2_k127_5883664_34 17 kDa outer membrane surface antigen - - - 0.0000000005698 70.0
CMS2_k127_5883664_35 Domain of unknown function (DUF4402) - - - 0.000001394 57.0
CMS2_k127_5883664_36 Domain of unknown function (DUF4402) - - - 0.0001282 51.0
CMS2_k127_5883664_37 Domain of unknown function (DUF4402) - - - 0.0006325 50.0
CMS2_k127_5883664_4 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 599.0
CMS2_k127_5883664_5 Probable molybdopterin binding domain K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 610.0
CMS2_k127_5883664_6 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 565.0
CMS2_k127_5883664_7 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 531.0
CMS2_k127_5883664_8 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 538.0
CMS2_k127_5883664_9 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 477.0
CMS2_k127_5984610_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0 1733.0
CMS2_k127_5984610_1 Adenylate cyclase - - - 8.25e-222 701.0
CMS2_k127_5984610_10 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 362.0
CMS2_k127_5984610_11 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 295.0
CMS2_k127_5984610_12 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15268 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 300.0
CMS2_k127_5984610_13 Tellurite resistance protein TerB K05801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 291.0
CMS2_k127_5984610_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000639 282.0
CMS2_k127_5984610_15 Belongs to the BI1 family K06890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003925 276.0
CMS2_k127_5984610_16 COG3023 Negative regulator of beta-lactamase expression K01447 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000001307 269.0
CMS2_k127_5984610_17 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007727 264.0
CMS2_k127_5984610_18 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001043 250.0
CMS2_k127_5984610_19 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000005071 213.0
CMS2_k127_5984610_2 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 3.964e-205 647.0
CMS2_k127_5984610_20 OmpA family - - - 0.000000000000000000000000000000000000000000000000005 191.0
CMS2_k127_5984610_21 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000009403 170.0
CMS2_k127_5984610_22 Histidine kinase - - - 0.00000000000000000000000000000000000000000003153 181.0
CMS2_k127_5984610_23 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000005453 154.0
CMS2_k127_5984610_24 Stringent starvation protein B K09985 - - 0.00000000000000000000000000000000000003468 150.0
CMS2_k127_5984610_25 YbaK prolyl-tRNA synthetase associated K19055 - - 0.0000000000000000000000000000000000001269 148.0
CMS2_k127_5984610_26 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000003852 139.0
CMS2_k127_5984610_27 COG0835 Chemotaxis signal transduction protein K03408 - - 0.00000000000000000000000000001012 134.0
CMS2_k127_5984610_28 Ribbon-helix-helix domain - - - 0.00000000000000001271 89.0
CMS2_k127_5984610_3 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 593.0
CMS2_k127_5984610_4 Bacterial regulatory protein, Fis family K10912 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 554.0
CMS2_k127_5984610_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 512.0
CMS2_k127_5984610_6 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 464.0
CMS2_k127_5984610_7 protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 483.0
CMS2_k127_5984610_8 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244,K21721 - 1.4.1.1,1.5.1.51,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 426.0
CMS2_k127_5984610_9 Aminotransferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 428.0
CMS2_k127_600836_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 8.473e-282 877.0
CMS2_k127_600836_1 COG1951 Tartrate dehydratase alpha subunit Fumarate hydratase class I, N-terminal domain K01677,K03779 - 4.2.1.2,4.2.1.32 0.00000000000000000000000000000000000000000000000000000000000003315 216.0
CMS2_k127_600836_2 succinate dehydrogenase K00247 - - 0.00000000000000000000000000000002804 129.0
CMS2_k127_6105156_0 Selenium-binding protein K17285 - - 9.593e-210 661.0
CMS2_k127_6105156_1 Domain of unknown function DUF87 K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 484.0
CMS2_k127_6105156_10 Adenylate cyclase - - - 0.0000000000000000000000000000000923 128.0
CMS2_k127_6105156_11 - - - - 0.0000000000000000000007121 100.0
CMS2_k127_6105156_2 SCO1/SenC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009084 425.0
CMS2_k127_6105156_3 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 365.0
CMS2_k127_6105156_4 CorA-like Mg2+ transporter protein K16074 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 327.0
CMS2_k127_6105156_5 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005547 254.0
CMS2_k127_6105156_6 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000003966 234.0
CMS2_k127_6105156_7 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000000000000000000001661 229.0
CMS2_k127_6105156_8 - - - - 0.0000000000000000000000000000000000000000000000000006653 191.0
CMS2_k127_6105156_9 signal sequence binding K07152 - - 0.000000000000000000000000000000000000000000000001052 185.0
CMS2_k127_6107371_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 7.086e-320 984.0
CMS2_k127_6107371_1 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 579.0
CMS2_k127_6107371_10 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 315.0
CMS2_k127_6107371_11 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 308.0
CMS2_k127_6107371_12 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002456 271.0
CMS2_k127_6107371_13 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001885 253.0
CMS2_k127_6107371_14 Protein of unknown function (DUF1194) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001393 243.0
CMS2_k127_6107371_15 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000002606 220.0
CMS2_k127_6107371_16 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000001433 202.0
CMS2_k127_6107371_17 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000006446 209.0
CMS2_k127_6107371_18 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.000000000000000000000000000000000000000000000000000336 188.0
CMS2_k127_6107371_19 thioesterase involved in non-ribosomal peptide biosynthesis - - - 0.000000000000000000000000000000000000000000000000008793 189.0
CMS2_k127_6107371_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 476.0
CMS2_k127_6107371_20 - - - - 0.0000000000000000000000000000000000000000000007585 170.0
CMS2_k127_6107371_21 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.000000000000000000000000000000000000000000001393 168.0
CMS2_k127_6107371_22 - - - - 0.000000000000000000000000000000000000000006924 159.0
CMS2_k127_6107371_23 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000000000000000004053 159.0
CMS2_k127_6107371_24 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000002959 153.0
CMS2_k127_6107371_25 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000000000000000000000000000002822 144.0
CMS2_k127_6107371_26 thiolester hydrolase activity - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000008137 142.0
CMS2_k127_6107371_27 - - - - 0.000000000000000000000000000000006113 136.0
CMS2_k127_6107371_28 Domain of unknown function (DUF4212) K14393 - - 0.0000000000000000000000000003962 117.0
CMS2_k127_6107371_29 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K12421 - - 0.00000000000000001879 85.0
CMS2_k127_6107371_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 443.0
CMS2_k127_6107371_30 pfam yhs - - - 0.0000000000005553 73.0
CMS2_k127_6107371_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 411.0
CMS2_k127_6107371_5 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 404.0
CMS2_k127_6107371_6 cytochrome p450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 376.0
CMS2_k127_6107371_7 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 341.0
CMS2_k127_6107371_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 353.0
CMS2_k127_6107371_9 glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 315.0
CMS2_k127_6123718_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 509.0
CMS2_k127_6123718_1 GTP cyclohydrolase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 298.0
CMS2_k127_6123718_2 Saccharopine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007812 272.0
CMS2_k127_6123718_3 protein affecting Mg2 Co2 transport K06195 - - 0.0000000000000000000000000000000000000000000000000000006616 195.0
CMS2_k127_6123718_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K18219 - - 0.0000000000000000000000000000000000000000652 158.0
CMS2_k127_6123718_6 Belongs to the PAPS reductase family. CysH subfamily K00390 - 1.8.4.10,1.8.4.8 0.0000000000000001254 89.0
CMS2_k127_6133833_0 Alpha beta hydrolase - GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 - 7.357e-212 681.0
CMS2_k127_6133833_1 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 622.0
CMS2_k127_6133833_10 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000001063 234.0
CMS2_k127_6133833_11 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000001754 227.0
CMS2_k127_6133833_12 - - - - 0.00000000000000000000000000000000000001047 148.0
CMS2_k127_6133833_13 Phospholipid N-methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000004847 153.0
CMS2_k127_6133833_14 WHG domain - - - 0.000000000000000000000000000000000002303 146.0
CMS2_k127_6133833_15 C-terminal domain of CHU protein family - - - 0.000000000000000000000059 105.0
CMS2_k127_6133833_16 - - - - 0.00000000000000000006103 93.0
CMS2_k127_6133833_18 Protein of unknown function (FYDLN_acid) - - - 0.000005543 51.0
CMS2_k127_6133833_19 Creatinase/Prolidase N-terminal domain - - - 0.00006381 46.0
CMS2_k127_6133833_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 603.0
CMS2_k127_6133833_3 succinate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 547.0
CMS2_k127_6133833_4 Protein of unknown function (DUF2167) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000926 271.0
CMS2_k127_6133833_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002412 272.0
CMS2_k127_6133833_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000005318 258.0
CMS2_k127_6133833_7 COG0558 Phosphatidylglycerophosphate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002536 246.0
CMS2_k127_6133833_8 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003498 247.0
CMS2_k127_6133833_9 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001286 240.0
CMS2_k127_6139154_0 Sarcosine oxidase, beta subunit K00303,K22084 - 1.5.3.1,1.5.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 530.0
CMS2_k127_6139154_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 452.0
CMS2_k127_6139154_2 Transcriptional K19591 - - 0.000000000000000000000000000000000000000000000004565 178.0
CMS2_k127_6142087_0 Penicillin amidase K01434 - 3.5.1.11 4.634e-216 695.0
CMS2_k127_6142087_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 524.0
CMS2_k127_6142087_10 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005103 243.0
CMS2_k127_6142087_11 Conserved hypothetical protein (DUF2461) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005926 241.0
CMS2_k127_6142087_12 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000002691 245.0
CMS2_k127_6142087_13 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000002385 203.0
CMS2_k127_6142087_14 - - - - 0.00000000000000000000000000000000000000000000000000005251 193.0
CMS2_k127_6142087_15 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000001693 184.0
CMS2_k127_6142087_16 cyclic nucleotide binding K07001,K10914,K21563 - - 0.0000000000000000000000000000000000000000000003874 175.0
CMS2_k127_6142087_17 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000007065 169.0
CMS2_k127_6142087_18 Transcriptional regulator - - - 0.0000000000000000000000000000000000000002837 157.0
CMS2_k127_6142087_19 SNARE associated Golgi protein - - - 0.000000000000000000000000000000245 136.0
CMS2_k127_6142087_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 445.0
CMS2_k127_6142087_20 RDD family - - - 0.0000000000000000000000000000004298 128.0
CMS2_k127_6142087_21 - - - - 0.0000000000000000008303 93.0
CMS2_k127_6142087_22 Late embryogenesis abundant protein - - - 0.000000000000002805 82.0
CMS2_k127_6142087_23 carbon monoxide dehydrogenase K03520 - 1.2.5.3 0.000000000001931 72.0
CMS2_k127_6142087_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 454.0
CMS2_k127_6142087_4 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 422.0
CMS2_k127_6142087_5 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 336.0
CMS2_k127_6142087_6 Dihydroorotate dehydrogenase K00226,K17723 - 1.3.1.1,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007949 333.0
CMS2_k127_6142087_7 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 314.0
CMS2_k127_6142087_8 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 304.0
CMS2_k127_6142087_9 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001587 282.0
CMS2_k127_6144287_0 Mg2 and Co2 transporter CorB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 537.0
CMS2_k127_6144287_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 464.0
CMS2_k127_6144287_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006526 268.0
CMS2_k127_6144287_3 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001212 238.0
CMS2_k127_6144287_4 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000001583 225.0
CMS2_k127_6144287_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000009841 207.0
CMS2_k127_6144287_6 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000006532 197.0
CMS2_k127_6144287_7 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000114 168.0
CMS2_k127_6144287_8 Belongs to the BolA IbaG family K05527,K22066 - - 0.00000000000000000000000000000004175 127.0
CMS2_k127_6144287_9 - - - - 0.00000003619 60.0
CMS2_k127_61478_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 1.465e-213 666.0
CMS2_k127_61478_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 482.0
CMS2_k127_61478_10 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000005468 219.0
CMS2_k127_61478_11 MlaD protein K02067,K06192 - - 0.000000000000000000000000000000000000000000000000000000000007655 222.0
CMS2_k127_61478_12 YHS domain protein - - - 0.0000000000000000000000000000000000000000000000000000001979 198.0
CMS2_k127_61478_13 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000000000000000000000000000000000004989 203.0
CMS2_k127_61478_14 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000001075 162.0
CMS2_k127_61478_15 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000006869 129.0
CMS2_k127_61478_16 ATPases associated with a variety of cellular activities K02065 - - 0.000000000000000000000004144 102.0
CMS2_k127_61478_17 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.000000000000006773 74.0
CMS2_k127_61478_2 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 445.0
CMS2_k127_61478_3 DNA-binding transcriptional activator of the SARP family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 362.0
CMS2_k127_61478_4 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 342.0
CMS2_k127_61478_5 K -dependent Na Ca K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004582 318.0
CMS2_k127_61478_6 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000000000000000000000000005928 261.0
CMS2_k127_61478_7 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000008013 256.0
CMS2_k127_61478_8 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008845 267.0
CMS2_k127_61478_9 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000218 221.0
CMS2_k127_6174155_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1251.0
CMS2_k127_6174155_1 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 1.018e-318 987.0
CMS2_k127_6174155_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 4.913e-206 647.0
CMS2_k127_6174155_11 Spermidine putrescine ABC transporter substrate-binding protein K02055 GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576 - 2.31e-202 636.0
CMS2_k127_6174155_12 4Fe-4S single cluster domain - - - 9.447e-195 619.0
CMS2_k127_6174155_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 573.0
CMS2_k127_6174155_14 cytochrome d1, heme region K19345 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 563.0
CMS2_k127_6174155_15 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 542.0
CMS2_k127_6174155_16 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 488.0
CMS2_k127_6174155_17 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 467.0
CMS2_k127_6174155_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 455.0
CMS2_k127_6174155_19 TOBE domain K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 446.0
CMS2_k127_6174155_2 Aldehyde ferredoxin oxidoreductase K03738 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016614,GO:0030151,GO:0033719,GO:0043167,GO:0043169,GO:0043546,GO:0044464,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0097159,GO:1901363 1.2.7.5 5.567e-292 910.0
CMS2_k127_6174155_20 spermidine putrescine K02054 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 432.0
CMS2_k127_6174155_21 ABC transporter permease K02053 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 409.0
CMS2_k127_6174155_22 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 359.0
CMS2_k127_6174155_23 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 351.0
CMS2_k127_6174155_24 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 331.0
CMS2_k127_6174155_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 314.0
CMS2_k127_6174155_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 292.0
CMS2_k127_6174155_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 287.0
CMS2_k127_6174155_28 glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 284.0
CMS2_k127_6174155_29 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008137 280.0
CMS2_k127_6174155_3 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.424e-289 900.0
CMS2_k127_6174155_30 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000157 265.0
CMS2_k127_6174155_31 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004096 260.0
CMS2_k127_6174155_32 COG0346 Lactoylglutathione lyase and related lyases K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000004358 256.0
CMS2_k127_6174155_33 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001887 262.0
CMS2_k127_6174155_34 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005826 253.0
CMS2_k127_6174155_35 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000003531 252.0
CMS2_k127_6174155_36 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000003211 245.0
CMS2_k127_6174155_37 transcriptional regulator AsnC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000008097 238.0
CMS2_k127_6174155_38 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000007887 207.0
CMS2_k127_6174155_39 membrane - - - 0.000000000000000000000000000000000000000000000000000000157 202.0
CMS2_k127_6174155_4 COG2010 Cytochrome c, mono- and diheme variants K15864 - 1.7.2.1,1.7.99.1 9.854e-247 767.0
CMS2_k127_6174155_40 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000001074 187.0
CMS2_k127_6174155_41 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000002989 187.0
CMS2_k127_6174155_42 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000619 177.0
CMS2_k127_6174155_43 Cupin domain - - - 0.0000000000000000000000000000000000000000000001063 171.0
CMS2_k127_6174155_44 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000003627 168.0
CMS2_k127_6174155_45 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000007529 169.0
CMS2_k127_6174155_46 - - - - 0.000000000000000000000000000000000000000000212 166.0
CMS2_k127_6174155_47 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000012 138.0
CMS2_k127_6174155_48 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.00000000000000000000000000001461 122.0
CMS2_k127_6174155_49 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.0000000000000000000000008372 108.0
CMS2_k127_6174155_5 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.83e-246 763.0
CMS2_k127_6174155_50 Protein of unknown function (DUF1467) - - - 0.00000000000000008308 82.0
CMS2_k127_6174155_51 Mut7-C ubiquitin - - - 0.000000000807 66.0
CMS2_k127_6174155_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 4.017e-239 754.0
CMS2_k127_6174155_7 hydrolase of the metallo-beta-lactamase superfamily K12574 - - 3.127e-226 713.0
CMS2_k127_6174155_8 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 5.856e-224 704.0
CMS2_k127_6174155_9 Cytochrome D1 heme domain - - - 4.156e-216 683.0
CMS2_k127_617798_0 rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 555.0
CMS2_k127_617798_1 COG2871 Na -transporting NADH ubiquinone oxidoreductase, subunit NqrF K00351,K16246 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 444.0
CMS2_k127_617798_10 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008144,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019842,GO:0030001,GO:0030964,GO:0032553,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044425,GO:0044464,GO:0048037,GO:0050136,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:1901265,GO:1901363,GO:1902444,GO:1902494 1.6.5.8 0.0000000000000005515 83.0
CMS2_k127_617798_2 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 329.0
CMS2_k127_617798_3 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 302.0
CMS2_k127_617798_4 Rnf-Nqr subunit, membrane protein K00350 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000001565 268.0
CMS2_k127_617798_5 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000008529 271.0
CMS2_k127_617798_6 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002296 240.0
CMS2_k127_617798_7 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000008283 241.0
CMS2_k127_617798_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000004714 225.0
CMS2_k127_617798_9 COG0517 FOG CBS domain - - - 0.0000000000000000000000000000000000000001669 156.0
CMS2_k127_6201247_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1668.0
CMS2_k127_6201247_1 COG0480 Translation elongation factors (GTPases) K02355 - - 2.789e-259 818.0
CMS2_k127_6201247_10 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 453.0
CMS2_k127_6201247_11 Mitochondrial fission ELM1 K07276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 340.0
CMS2_k127_6201247_12 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 330.0
CMS2_k127_6201247_13 Ketopantoate reductase PanE/ApbA C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 329.0
CMS2_k127_6201247_14 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008108 262.0
CMS2_k127_6201247_15 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002495 256.0
CMS2_k127_6201247_16 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000002331 231.0
CMS2_k127_6201247_17 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000005406 220.0
CMS2_k127_6201247_18 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000001189 212.0
CMS2_k127_6201247_19 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000001086 175.0
CMS2_k127_6201247_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.597e-207 662.0
CMS2_k127_6201247_3 DegT/DnrJ/EryC1/StrS aminotransferase family K00812 - 2.6.1.1 3.631e-200 632.0
CMS2_k127_6201247_4 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 610.0
CMS2_k127_6201247_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 576.0
CMS2_k127_6201247_6 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 468.0
CMS2_k127_6201247_7 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 451.0
CMS2_k127_6201247_8 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 447.0
CMS2_k127_6201247_9 CoA-transferase family III K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 445.0
CMS2_k127_6206395_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008324 569.0
CMS2_k127_6206395_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 496.0
CMS2_k127_6206395_2 FAD binding domain K00481 - 1.14.13.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 390.0
CMS2_k127_6206395_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000001374 195.0
CMS2_k127_6211656_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 528.0
CMS2_k127_6211656_1 Chain length determinant protein K16554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 523.0
CMS2_k127_6211656_2 Esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 512.0
CMS2_k127_6211656_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 418.0
CMS2_k127_6211656_4 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 316.0
CMS2_k127_6211656_5 Belongs to the SfsA family K06206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 289.0
CMS2_k127_6211656_6 Domain of unknown function (DUF4405) - - - 0.000000000000000000000000000000000000000000000000000000000000000002073 237.0
CMS2_k127_6211656_8 Putative beta-barrel porin 2 - - - 0.00000000000000000000000000000000000000000000000000000000001629 217.0
CMS2_k127_6211656_9 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000000004788 199.0
CMS2_k127_6246982_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 7.296e-320 992.0
CMS2_k127_6246982_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 7.872e-197 629.0
CMS2_k127_6246982_10 Uncharacterized ACR, COG1399 - - - 0.00000000000000000000000002659 114.0
CMS2_k127_6246982_11 peptidase activity, acting on L-amino acid peptides - - - 0.0000000001723 72.0
CMS2_k127_6246982_2 metabolite transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 419.0
CMS2_k127_6246982_3 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 412.0
CMS2_k127_6246982_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 347.0
CMS2_k127_6246982_5 Bacterial periplasmic substrate-binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002216 261.0
CMS2_k127_6246982_6 Including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000000000000000000002131 207.0
CMS2_k127_6246982_7 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000009338 171.0
CMS2_k127_6246982_8 Ubiquinol-cytochrome C chaperone K17662 - - 0.0000000000000000000000000000000006631 139.0
CMS2_k127_6246982_9 COG2913 Small protein A (tmRNA-binding) - - - 0.00000000000000000000000000000003141 133.0
CMS2_k127_630271_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1023.0
CMS2_k127_630271_1 IMP dehydrogenase / GMP reductase domain K22083 - 2.1.1.21 5.308e-306 948.0
CMS2_k127_630271_10 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009316 542.0
CMS2_k127_630271_11 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 529.0
CMS2_k127_630271_12 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 496.0
CMS2_k127_630271_13 including yeast histone deacetylase and acetoin utilization protein' - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 477.0
CMS2_k127_630271_14 Iron-containing alcohol dehydrogenase K00043,K13954 - 1.1.1.1,1.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007005 477.0
CMS2_k127_630271_15 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 464.0
CMS2_k127_630271_16 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 443.0
CMS2_k127_630271_17 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 434.0
CMS2_k127_630271_18 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 426.0
CMS2_k127_630271_19 Pilus formation protein N terminal region K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 424.0
CMS2_k127_630271_2 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases - - - 5.142e-259 824.0
CMS2_k127_630271_20 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072,K11076 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 414.0
CMS2_k127_630271_21 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 395.0
CMS2_k127_630271_22 Required for the activity of the bacterial periplasmic transport system of putrescine K11069,K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 385.0
CMS2_k127_630271_23 ABC transporter K02003,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 349.0
CMS2_k127_630271_24 PFAM binding-protein-dependent transport systems inner membrane component K11071,K11075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 326.0
CMS2_k127_630271_25 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 345.0
CMS2_k127_630271_26 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 322.0
CMS2_k127_630271_27 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 331.0
CMS2_k127_630271_28 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 297.0
CMS2_k127_630271_29 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001305 284.0
CMS2_k127_630271_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 1.8e-257 799.0
CMS2_k127_630271_30 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 278.0
CMS2_k127_630271_31 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003053 295.0
CMS2_k127_630271_32 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000207 271.0
CMS2_k127_630271_33 Flp pilus assembly protein RcpC/CpaB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001062 267.0
CMS2_k127_630271_34 Protein of unknown function (DUF861) K06995 - - 0.00000000000000000000000000000000000000000000000000000000001664 207.0
CMS2_k127_630271_35 Type II secretion system (T2SS), protein F K12511 - - 0.00000000000000000000000000000000000000000000000000000000007236 216.0
CMS2_k127_630271_36 Glutamine amidotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000002107 216.0
CMS2_k127_630271_37 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000002192 217.0
CMS2_k127_630271_38 Pilus assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000007033 216.0
CMS2_k127_630271_39 FCD - - - 0.00000000000000000000000000000000000000000000000000000000122 212.0
CMS2_k127_630271_4 FtsX-like permease family K02004 - - 4.502e-246 784.0
CMS2_k127_630271_40 Type II secretion system (T2SS), protein F - - - 0.000000000000000000000000000000000000000000000000000000003239 216.0
CMS2_k127_630271_41 Putative Flp pilus-assembly TadE/G-like - - - 0.000000000000000000000000000000000000000000000000000000142 215.0
CMS2_k127_630271_42 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000006677 207.0
CMS2_k127_630271_43 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000007854 181.0
CMS2_k127_630271_44 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000004896 175.0
CMS2_k127_630271_45 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000001303 173.0
CMS2_k127_630271_46 methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000001005 181.0
CMS2_k127_630271_47 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000004098 171.0
CMS2_k127_630271_48 Protein of unknown function (DUF1244) K09948 - - 0.000000000000000000000000000000000000000001549 160.0
CMS2_k127_630271_49 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000004642 159.0
CMS2_k127_630271_5 UDP-glucoronosyl and UDP-glucosyl transferase - - - 1.39e-225 704.0
CMS2_k127_630271_50 protein conserved in bacteria - - - 0.00000000000000000000000000000000000001106 151.0
CMS2_k127_630271_51 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000001499 153.0
CMS2_k127_630271_52 Uncharacterized protein conserved in bacteria (DUF2312) - - - 0.0000000000000000000000000001681 123.0
CMS2_k127_630271_53 PFAM TadE family protein - - - 0.0000000000000000000000000007896 119.0
CMS2_k127_630271_54 Histidine kinase K02480 - 2.7.13.3 0.000000000000000000000000007546 128.0
CMS2_k127_630271_55 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000003662 107.0
CMS2_k127_630271_56 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000002516 100.0
CMS2_k127_630271_57 Rhodanese-related sulfurtransferase - - - 0.00000000000000000000009165 103.0
CMS2_k127_630271_58 Protein of unknown function (DUF2817) - - - 0.0000000000000000000003636 108.0
CMS2_k127_630271_59 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000002695 73.0
CMS2_k127_630271_6 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.519e-202 640.0
CMS2_k127_630271_60 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000002626 72.0
CMS2_k127_630271_61 TadE-like protein - - - 0.000001263 58.0
CMS2_k127_630271_62 Flp/Fap pilin component K02651 - - 0.0003852 45.0
CMS2_k127_630271_7 Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 609.0
CMS2_k127_630271_8 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 602.0
CMS2_k127_630271_9 Type II/IV secretion system protein K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 578.0
CMS2_k127_6346091_0 reductase, alpha subunit K00394 - 1.8.99.2 0.0 1204.0
CMS2_k127_6346091_1 reductase, alpha subunit K00394 - 1.8.99.2 6.45e-307 951.0
CMS2_k127_6346091_10 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 424.0
CMS2_k127_6346091_11 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 413.0
CMS2_k127_6346091_12 Homocysteine S-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 396.0
CMS2_k127_6346091_13 Pfam Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 393.0
CMS2_k127_6346091_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 376.0
CMS2_k127_6346091_15 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 359.0
CMS2_k127_6346091_16 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 355.0
CMS2_k127_6346091_17 reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 316.0
CMS2_k127_6346091_18 PFAM conserved K02069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 318.0
CMS2_k127_6346091_19 transport system, ATPase component K05779 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009628 265.0
CMS2_k127_6346091_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 7.212e-274 855.0
CMS2_k127_6346091_20 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000992 249.0
CMS2_k127_6346091_21 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001113 252.0
CMS2_k127_6346091_22 transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000113 262.0
CMS2_k127_6346091_23 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.000000000000000000000000000000000000000000000000000000000000000000002645 252.0
CMS2_k127_6346091_24 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000001399 236.0
CMS2_k127_6346091_25 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000538 242.0
CMS2_k127_6346091_26 COG2030 Acyl dehydratase K17865 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016043,GO:0016829,GO:0016835,GO:0016836,GO:0022607,GO:0042620,GO:0042621,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901576 4.2.1.55 0.00000000000000000000000000000000000000000000000000000000001722 211.0
CMS2_k127_6346091_27 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000001091 215.0
CMS2_k127_6346091_28 reductase, beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000001257 208.0
CMS2_k127_6346091_29 Belongs to the Fur family K09823 - - 0.00000000000000000000000000000000000000000000000000000001301 202.0
CMS2_k127_6346091_3 transport system, permease component K05778 - - 2.147e-210 672.0
CMS2_k127_6346091_30 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000004291 202.0
CMS2_k127_6346091_31 TPR repeat - - - 0.000000000000000000000000000000000000000000003781 177.0
CMS2_k127_6346091_32 - - - - 0.000000000000000000000000000000000000000000005861 168.0
CMS2_k127_6346091_33 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000006594 162.0
CMS2_k127_6346091_34 MazG-like family - - - 0.0000000000000000000000000000000003387 134.0
CMS2_k127_6346091_35 COG1530 Ribonucleases G and E K08301 - - 0.000000000000000000000000000000004962 137.0
CMS2_k127_6346091_36 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000004619 127.0
CMS2_k127_6346091_37 sulfurtransferase - - - 0.000000000000000000000007006 103.0
CMS2_k127_6346091_38 COG5126 Ca2 -binding protein (EF-Hand superfamily - - - 0.000000000000000002144 94.0
CMS2_k127_6346091_39 - - - - 0.000000000000000002967 99.0
CMS2_k127_6346091_4 transport system periplasmic component K05777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 540.0
CMS2_k127_6346091_40 - - - - 0.0000000000000001246 83.0
CMS2_k127_6346091_41 zinc ion binding K00859,K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 2.7.1.24 0.000000000001976 78.0
CMS2_k127_6346091_42 Tail protein - - - 0.000002621 59.0
CMS2_k127_6346091_43 Resolvase - - - 0.000003965 49.0
CMS2_k127_6346091_5 Ethylbenzene dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 539.0
CMS2_k127_6346091_6 Belongs to the proline racemase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 528.0
CMS2_k127_6346091_7 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 497.0
CMS2_k127_6346091_8 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 474.0
CMS2_k127_6346091_9 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 448.0
CMS2_k127_6374429_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2296.0
CMS2_k127_6374429_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.5e-322 996.0
CMS2_k127_6374429_10 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 345.0
CMS2_k127_6374429_11 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 317.0
CMS2_k127_6374429_12 3-5 exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006218 309.0
CMS2_k127_6374429_13 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005038 269.0
CMS2_k127_6374429_14 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001707 249.0
CMS2_k127_6374429_15 COG0859 ADP-heptose LPS heptosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000005501 235.0
CMS2_k127_6374429_16 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.000000000000000000000000000000000000000000000000000000000001558 214.0
CMS2_k127_6374429_17 OstA-like protein K09774 - - 0.0000000000000000000000000000000000000000000000000003664 196.0
CMS2_k127_6374429_18 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000003879 177.0
CMS2_k127_6374429_19 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000003233 135.0
CMS2_k127_6374429_2 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 - 1.4.1.13,1.4.1.14 6.448e-229 718.0
CMS2_k127_6374429_20 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000001467 84.0
CMS2_k127_6374429_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 533.0
CMS2_k127_6374429_4 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 455.0
CMS2_k127_6374429_5 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 425.0
CMS2_k127_6374429_6 ABC transporter, ATP-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 398.0
CMS2_k127_6374429_7 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 360.0
CMS2_k127_6374429_8 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 353.0
CMS2_k127_6374429_9 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 345.0
CMS2_k127_6383422_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 1.465e-290 908.0
CMS2_k127_6383422_1 Glycosyl hydrolases family 15 - - - 2.142e-274 854.0
CMS2_k127_6383422_10 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 546.0
CMS2_k127_6383422_11 Belongs to the phosphoglycerate kinase family K00927 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 522.0
CMS2_k127_6383422_12 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 486.0
CMS2_k127_6383422_13 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 420.0
CMS2_k127_6383422_14 Mandelate Racemase Muconate Lactonizing K01781,K20023,K20549 - 4.2.1.156,4.2.1.42,5.1.2.2,5.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 412.0
CMS2_k127_6383422_15 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 421.0
CMS2_k127_6383422_16 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009644 381.0
CMS2_k127_6383422_17 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 351.0
CMS2_k127_6383422_18 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 340.0
CMS2_k127_6383422_19 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 344.0
CMS2_k127_6383422_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.603e-218 686.0
CMS2_k127_6383422_20 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 329.0
CMS2_k127_6383422_21 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 328.0
CMS2_k127_6383422_22 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000826 340.0
CMS2_k127_6383422_23 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000964 285.0
CMS2_k127_6383422_24 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001111 260.0
CMS2_k127_6383422_25 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000003357 235.0
CMS2_k127_6383422_26 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000005142 222.0
CMS2_k127_6383422_27 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000002455 211.0
CMS2_k127_6383422_28 protein conserved in bacteria K09921 - - 0.0000000000000000000000000000000000000000000000000000000009512 208.0
CMS2_k127_6383422_29 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000001405 204.0
CMS2_k127_6383422_3 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 2.397e-214 674.0
CMS2_k127_6383422_30 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000006286 200.0
CMS2_k127_6383422_31 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000666 193.0
CMS2_k127_6383422_32 phosphatase homologous to the C-terminal domain of histone macroH2A1 - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000001777 183.0
CMS2_k127_6383422_33 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000004172 168.0
CMS2_k127_6383422_34 Putative mono-oxygenase ydhR - - - 0.00000000000000000000000000000418 121.0
CMS2_k127_6383422_35 transduction histidine kinase - - - 0.0000000000000000000000001806 119.0
CMS2_k127_6383422_36 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000009641 111.0
CMS2_k127_6383422_37 transcriptional regulator - - - 0.00000000000000000001793 96.0
CMS2_k127_6383422_39 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00001685 57.0
CMS2_k127_6383422_4 COG1042 Acyl-CoA synthetase (NDP forming) K09181 - - 2.071e-212 676.0
CMS2_k127_6383422_40 response to cobalt ion - - - 0.00006773 51.0
CMS2_k127_6383422_5 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 4.04e-207 653.0
CMS2_k127_6383422_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 592.0
CMS2_k127_6383422_7 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008375 590.0
CMS2_k127_6383422_8 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 561.0
CMS2_k127_6383422_9 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 558.0
CMS2_k127_6387142_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 400.0
CMS2_k127_6387142_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004477 288.0
CMS2_k127_6387142_2 Domain of unknown function (DUF4132) - - - 0.0000000000000000000000000000000000000000000000000000000000000001607 242.0
CMS2_k127_6387142_3 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000001557 205.0
CMS2_k127_6387142_4 - - - - 0.0000000000000000000000000000004103 126.0
CMS2_k127_6387142_5 Transition state regulatory protein AbrB K07120 - - 0.000000000000000004843 92.0
CMS2_k127_6474181_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1147.0
CMS2_k127_6474181_1 KH domain K00962 GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0 1058.0
CMS2_k127_6474181_10 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.97e-198 627.0
CMS2_k127_6474181_11 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 7.248e-195 621.0
CMS2_k127_6474181_12 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 555.0
CMS2_k127_6474181_13 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008011 558.0
CMS2_k127_6474181_14 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 512.0
CMS2_k127_6474181_15 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 506.0
CMS2_k127_6474181_16 Cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 476.0
CMS2_k127_6474181_17 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 476.0
CMS2_k127_6474181_18 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 467.0
CMS2_k127_6474181_19 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 454.0
CMS2_k127_6474181_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.858e-311 973.0
CMS2_k127_6474181_20 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 427.0
CMS2_k127_6474181_21 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 405.0
CMS2_k127_6474181_22 Precorrin-4 K05936 - 2.1.1.133,2.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005716 405.0
CMS2_k127_6474181_23 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 399.0
CMS2_k127_6474181_24 COG0477 Permeases of the major facilitator superfamily K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 402.0
CMS2_k127_6474181_25 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 385.0
CMS2_k127_6474181_26 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 391.0
CMS2_k127_6474181_27 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 377.0
CMS2_k127_6474181_28 xylanase chitin deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 366.0
CMS2_k127_6474181_29 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029,K21147 - 2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 358.0
CMS2_k127_6474181_3 Participates in both transcription termination and antitermination K02600 - - 1.005e-231 728.0
CMS2_k127_6474181_30 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 355.0
CMS2_k127_6474181_31 COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 343.0
CMS2_k127_6474181_32 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 338.0
CMS2_k127_6474181_33 Sugar (and other) transporter K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 332.0
CMS2_k127_6474181_34 COG1253 Hemolysins and related proteins containing CBS domains K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 320.0
CMS2_k127_6474181_35 Precorrin-2 K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 304.0
CMS2_k127_6474181_36 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 304.0
CMS2_k127_6474181_37 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 292.0
CMS2_k127_6474181_38 xylanase chitin deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001663 295.0
CMS2_k127_6474181_39 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001466 268.0
CMS2_k127_6474181_4 Cysteine-rich domain - - - 1.573e-216 680.0
CMS2_k127_6474181_40 COG0694 Thioredoxin-like proteins and domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007459 263.0
CMS2_k127_6474181_41 xylanase chitin deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003546 272.0
CMS2_k127_6474181_42 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002943 256.0
CMS2_k127_6474181_43 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000007063 258.0
CMS2_k127_6474181_44 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004608 251.0
CMS2_k127_6474181_45 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000000000002011 234.0
CMS2_k127_6474181_46 reductase K05895 - 1.3.1.106,1.3.1.54 0.00000000000000000000000000000000000000000000000000000000000001568 223.0
CMS2_k127_6474181_47 FlgJ-related protein K03796 - - 0.00000000000000000000000000000000000000000000000000000000000006679 226.0
CMS2_k127_6474181_48 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000000000000000000000000007942 222.0
CMS2_k127_6474181_49 ROS/MUCR transcriptional regulator protein - - - 0.0000000000000000000000000000000000000000000000000000000005392 205.0
CMS2_k127_6474181_5 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 5.13e-212 662.0
CMS2_k127_6474181_50 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000001794 213.0
CMS2_k127_6474181_51 Belongs to the UPF0260 family K09160 - - 0.00000000000000000000000000000000000000000000000000000001569 224.0
CMS2_k127_6474181_52 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.00000000000000000000000000000000000000000000000000000003405 203.0
CMS2_k127_6474181_53 transcriptional - - - 0.00000000000000000000000000000000000000000000000000000246 195.0
CMS2_k127_6474181_54 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000000000000000000003227 193.0
CMS2_k127_6474181_55 Belongs to the Fur family K09826 - - 0.000000000000000000000000000000000000000000000000000006352 192.0
CMS2_k127_6474181_56 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000001358 190.0
CMS2_k127_6474181_57 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000002935 188.0
CMS2_k127_6474181_58 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000008854 185.0
CMS2_k127_6474181_59 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000001046 201.0
CMS2_k127_6474181_6 Precorrin-3B K05934,K13541 - 2.1.1.131,3.7.1.12 1.911e-207 668.0
CMS2_k127_6474181_60 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000004757 190.0
CMS2_k127_6474181_61 protein conserved in bacteria K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000004987 174.0
CMS2_k127_6474181_62 Glycoprotease family - - - 0.0000000000000000000000000000000000000000006431 166.0
CMS2_k127_6474181_63 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000008956 166.0
CMS2_k127_6474181_64 COG3474 Cytochrome c2 K08738 - - 0.000000000000000000000000000000000000006344 153.0
CMS2_k127_6474181_65 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000001257 141.0
CMS2_k127_6474181_66 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000369 141.0
CMS2_k127_6474181_67 Ankyrin repeat K06867 - - 0.0000000000000000000000000000005765 129.0
CMS2_k127_6474181_68 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000004891 120.0
CMS2_k127_6474181_69 - - - - 0.000000000000000000000002662 106.0
CMS2_k127_6474181_7 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 4.249e-207 652.0
CMS2_k127_6474181_70 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000001597 105.0
CMS2_k127_6474181_8 COG0744 Membrane carboxypeptidase (penicillin-binding protein) K05366 - 2.4.1.129,3.4.16.4 4.13e-201 644.0
CMS2_k127_6474181_9 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 5.825e-200 629.0
CMS2_k127_6485311_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 8.861e-232 732.0
CMS2_k127_6485311_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 580.0
CMS2_k127_6485311_2 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 339.0
CMS2_k127_6485311_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 352.0
CMS2_k127_6485311_4 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 332.0
CMS2_k127_6485311_5 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000000000000000624 188.0
CMS2_k127_6485311_6 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000003512 128.0
CMS2_k127_6485311_7 Pfam:Ureidogly_hydro K01483 - 4.3.2.3 0.0000000000000000000000000005932 118.0
CMS2_k127_6494568_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1285.0
CMS2_k127_6494568_1 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.0 1185.0
CMS2_k127_6494568_10 Bacterial protein of unknown function (DUF898) - - - 0.0000000000000000000000000000000000000000000001311 184.0
CMS2_k127_6494568_11 Peptidase family M48 - - - 0.000000000000000000000000000000000000000001692 171.0
CMS2_k127_6494568_12 diguanylate cyclase - - - 0.0000000000000000001199 98.0
CMS2_k127_6494568_13 Putative prokaryotic signal transducing protein - - - 0.00000000000000005079 92.0
CMS2_k127_6494568_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000002244 70.0
CMS2_k127_6494568_15 - - - - 0.000000000003173 72.0
CMS2_k127_6494568_16 peptidyl-tyrosine sulfation - - - 0.000000000005305 78.0
CMS2_k127_6494568_17 - - - - 0.0000000002202 66.0
CMS2_k127_6494568_19 C-lobe handle domain of Tf-binding protein B - - - 0.00001689 56.0
CMS2_k127_6494568_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.363e-265 835.0
CMS2_k127_6494568_3 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008334 522.0
CMS2_k127_6494568_4 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 464.0
CMS2_k127_6494568_5 transcriptional regulator K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 324.0
CMS2_k127_6494568_6 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 312.0
CMS2_k127_6494568_7 Peptidase family S49 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 293.0
CMS2_k127_6494568_8 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006582 271.0
CMS2_k127_6494568_9 chemotaxis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002213 276.0
CMS2_k127_6518106_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 415.0
CMS2_k127_6518106_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 409.0
CMS2_k127_6518106_10 Dihaem cytochrome c - - - 0.0000000000000000000000000000000000000000000000004141 179.0
CMS2_k127_6518106_11 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000002216 142.0
CMS2_k127_6518106_12 Protein of unknown function (DUF1318) - - - 0.000000000000000000000000002316 115.0
CMS2_k127_6518106_13 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000157 117.0
CMS2_k127_6518106_14 Peptidase propeptide and YPEB domain - - - 0.0000000000000000000001364 102.0
CMS2_k127_6518106_15 Peptidase propeptide and YPEB domain - - - 0.0000000000000000009058 88.0
CMS2_k127_6518106_16 YnbE-like lipoprotein - - - 0.000000000000000173 81.0
CMS2_k127_6518106_17 Pfam:DUF1049 - - - 0.00000001716 58.0
CMS2_k127_6518106_2 Belongs to the LDH2 MDH2 oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 344.0
CMS2_k127_6518106_3 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 340.0
CMS2_k127_6518106_4 Putative 2OG-Fe(II) oxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 297.0
CMS2_k127_6518106_5 Dihaem cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 305.0
CMS2_k127_6518106_6 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002453 252.0
CMS2_k127_6518106_7 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002993 240.0
CMS2_k127_6518106_8 Dicarboxylate transport - - - 0.00000000000000000000000000000000000000000000000000000000000004548 243.0
CMS2_k127_6518106_9 Ceramidase - - - 0.0000000000000000000000000000000000000000000000000000001256 205.0
CMS2_k127_65238_0 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 530.0
CMS2_k127_65238_1 COG2998 ABC-type tungstate transport system, permease component K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 410.0
CMS2_k127_65238_2 ABC-type tungstate transport system, periplasmic component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 331.0
CMS2_k127_65238_3 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002982 278.0
CMS2_k127_65238_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000008053 255.0
CMS2_k127_65238_5 NADH flavin oxidoreductase NADH oxidase K21833 - - 0.0000000000000000000000000000000000000000000000000000109 192.0
CMS2_k127_65238_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000000000000000000004341 150.0
CMS2_k127_65238_7 Protein of unknown function (DUF559) - - - 0.00000000000000000000000000000002704 128.0
CMS2_k127_65238_8 Helix-turn-helix domain - - - 0.0000000000000000000000000002538 115.0
CMS2_k127_6564490_0 Heat shock 70 kDa protein K04043 - - 6.065e-309 951.0
CMS2_k127_6564490_1 Domain of unknown function (DUF1848) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 356.0
CMS2_k127_6564490_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000001067 182.0
CMS2_k127_6564490_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000006296 170.0
CMS2_k127_6594147_0 COG0513 Superfamily II DNA and RNA helicases K17675 - 3.6.4.13 6.101e-278 877.0
CMS2_k127_6594147_1 Circularly permuted ATP-grasp type 2 - - - 6.528e-261 808.0
CMS2_k127_6594147_10 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000001401 87.0
CMS2_k127_6594147_11 - - - - 0.00000001656 66.0
CMS2_k127_6594147_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 441.0
CMS2_k127_6594147_3 Proteasome subunit K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 383.0
CMS2_k127_6594147_4 Transglutaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 372.0
CMS2_k127_6594147_5 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 327.0
CMS2_k127_6594147_6 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.00000000000000000000000000000000000004474 148.0
CMS2_k127_6594147_7 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000001084 147.0
CMS2_k127_6594147_8 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000001264 131.0
CMS2_k127_6594147_9 COG0484 DnaJ-class molecular chaperone with C-terminal Zn finger domain - - - 0.000000000000000001095 98.0
CMS2_k127_661357_0 PFAM Cys Met metabolism PLP-dependent enzyme K01760 GO:0000096,GO:0000098,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004121,GO:0006082,GO:0006090,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006520,GO:0006534,GO:0006725,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009093,GO:0009987,GO:0016054,GO:0016829,GO:0016846,GO:0019448,GO:0019450,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044273,GO:0044281,GO:0044282,GO:0046395,GO:0046439,GO:0046483,GO:0047804,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1990414 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 484.0
CMS2_k127_661357_1 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004287 485.0
CMS2_k127_661357_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005031 415.0
CMS2_k127_661357_3 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 351.0
CMS2_k127_661357_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006996 252.0
CMS2_k127_661357_5 YsiA-like protein, C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000003022 235.0
CMS2_k127_661357_6 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000000008478 185.0
CMS2_k127_661357_7 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244,K21721 - 1.4.1.1,1.5.1.51,4.3.1.12 0.0000000000000000000000002071 108.0
CMS2_k127_6796074_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1542.0
CMS2_k127_6796074_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1234.0
CMS2_k127_6796074_10 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 512.0
CMS2_k127_6796074_11 DegT/DnrJ/EryC1/StrS aminotransferase family K00812,K12252 - 2.6.1.1,2.6.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 469.0
CMS2_k127_6796074_12 Belongs to the GcvT family K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 467.0
CMS2_k127_6796074_13 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 404.0
CMS2_k127_6796074_14 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 403.0
CMS2_k127_6796074_15 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 400.0
CMS2_k127_6796074_16 Putrescine transport system permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 344.0
CMS2_k127_6796074_17 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 312.0
CMS2_k127_6796074_18 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 300.0
CMS2_k127_6796074_19 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000000000000000000001183 221.0
CMS2_k127_6796074_2 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K00317 - 1.5.8.1,1.5.8.2 2.481e-310 965.0
CMS2_k127_6796074_20 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000001422 219.0
CMS2_k127_6796074_21 BetI-type transcriptional repressor, C-terminal - - - 0.00000000000000000000000000000000000000000000000001043 188.0
CMS2_k127_6796074_22 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.0000000813 59.0
CMS2_k127_6796074_3 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K00317 - 1.5.8.1,1.5.8.2 6.589e-282 881.0
CMS2_k127_6796074_4 NADH:flavin oxidoreductase / NADH oxidase family K00317 - 1.5.8.1,1.5.8.2 3.378e-275 861.0
CMS2_k127_6796074_5 COG1233 Phytoene dehydrogenase and related - - - 8.538e-237 743.0
CMS2_k127_6796074_6 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 6.172e-231 722.0
CMS2_k127_6796074_7 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 586.0
CMS2_k127_6796074_8 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 556.0
CMS2_k127_6796074_9 Phytoene dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 543.0
CMS2_k127_684026_0 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 411.0
CMS2_k127_684026_1 proline dipeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 400.0
CMS2_k127_684026_2 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 351.0
CMS2_k127_684026_3 redox protein, regulator of disulfide bond formation K07397 - - 0.00000000000000000000000000000000000000000000000004612 188.0
CMS2_k127_684026_4 TROVE domain K11089 - - 0.000000000000000000000000000001722 123.0
CMS2_k127_684026_5 Bacterial protein of unknown function (DUF934) - - - 0.000006884 49.0
CMS2_k127_6914101_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 7.365e-198 632.0
CMS2_k127_6914101_1 ABC transporter substrate-binding protein PnrA-like K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 508.0
CMS2_k127_6914101_10 Transcriptional regulator K02623 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 323.0
CMS2_k127_6914101_11 Dioxygenase K00448 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003334 286.0
CMS2_k127_6914101_12 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005089 261.0
CMS2_k127_6914101_13 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000000000000000000000000000000000000000000000000000003533 213.0
CMS2_k127_6914101_14 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000001919 211.0
CMS2_k127_6914101_15 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01055,K14727 - 3.1.1.24,4.1.1.44 0.0000000000000000000000000000000000000000000000002117 179.0
CMS2_k127_6914101_16 transcriptional regulator - - - 0.000000000000000000000000003666 114.0
CMS2_k127_6914101_17 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000001483 91.0
CMS2_k127_6914101_2 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 464.0
CMS2_k127_6914101_3 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 440.0
CMS2_k127_6914101_4 Dual specificity phosphatase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 435.0
CMS2_k127_6914101_5 Protocatechuate 3,4-dioxygenase beta subunit N terminal K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 388.0
CMS2_k127_6914101_6 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 389.0
CMS2_k127_6914101_7 Succinylglutamate desuccinylase / Aspartoacylase family K06987,K15784 - 3.5.1.125 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 362.0
CMS2_k127_6914101_8 Short-chain dehydrogenase reductase SDR K21883 - 1.1.1.401 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 348.0
CMS2_k127_6914101_9 Ndr family K01055,K14727 - 3.1.1.24,4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 349.0
CMS2_k127_6950928_0 Glutamine amidotransferase domain K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.749e-279 870.0
CMS2_k127_6950928_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 6.95e-276 854.0
CMS2_k127_6950928_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 526.0
CMS2_k127_6950928_3 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000009871 207.0
CMS2_k127_6950928_4 Thioesterase - - - 0.00000000000000000000000000000000000002348 150.0
CMS2_k127_6950928_5 Delta-aminolevulinic acid dehydratase K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000001428 94.0
CMS2_k127_7020910_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 2.866e-296 917.0
CMS2_k127_7020910_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 4.194e-261 812.0
CMS2_k127_7020910_10 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 302.0
CMS2_k127_7020910_11 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 298.0
CMS2_k127_7020910_12 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002477 256.0
CMS2_k127_7020910_13 Acetolactate synthase small K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000886 227.0
CMS2_k127_7020910_14 shape-determining protein K03571 - - 0.000000000000000000000000000000000001679 144.0
CMS2_k127_7020910_15 FecR protein - - - 0.0000000000000000000000006042 118.0
CMS2_k127_7020910_16 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000002248 94.0
CMS2_k127_7020910_17 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000008341 68.0
CMS2_k127_7020910_18 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000001235 63.0
CMS2_k127_7020910_19 FecR protein - - - 0.000002823 52.0
CMS2_k127_7020910_2 Cell division protein FtsI penicillin-binding protein 2 K05515 - 3.4.16.4 1.394e-200 647.0
CMS2_k127_7020910_20 FecR protein - - - 0.0008692 46.0
CMS2_k127_7020910_3 CHASE2 K01768 - 4.6.1.1 1.579e-197 639.0
CMS2_k127_7020910_4 Rod shape-determining protein MreB K03569 - - 2.133e-195 612.0
CMS2_k127_7020910_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 584.0
CMS2_k127_7020910_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 527.0
CMS2_k127_7020910_7 Cell cycle protein K03588,K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 464.0
CMS2_k127_7020910_8 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 362.0
CMS2_k127_7020910_9 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 359.0
CMS2_k127_71046_0 Aldo/keto reductase family K05882 - 1.1.1.91 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 443.0
CMS2_k127_71046_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 408.0
CMS2_k127_71046_10 Transition state regulatory protein AbrB K07120 - - 0.00000000000000000000000000000007946 134.0
CMS2_k127_71046_11 COG3637 Opacity protein and related surface antigens - - - 0.00000000007652 72.0
CMS2_k127_71046_12 Protein of unknown function (DUF2914) - - - 0.000001976 58.0
CMS2_k127_71046_2 Subtilase family K17734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 411.0
CMS2_k127_71046_3 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 387.0
CMS2_k127_71046_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003681 237.0
CMS2_k127_71046_5 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000005184 202.0
CMS2_k127_71046_6 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000009719 166.0
CMS2_k127_71046_7 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000008119 153.0
CMS2_k127_71046_8 - - - - 0.000000000000000000000000000000000008003 153.0
CMS2_k127_71046_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000005589 142.0
CMS2_k127_732836_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 2.124e-288 892.0
CMS2_k127_732836_1 Acyl-CoA dehydrogenase, middle domain K00253 - 1.3.8.4 1.062e-215 679.0
CMS2_k127_732836_10 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000001741 233.0
CMS2_k127_732836_11 Enoyl-CoA hydratase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000006331 232.0
CMS2_k127_732836_12 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000459 199.0
CMS2_k127_732836_13 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000000253 191.0
CMS2_k127_732836_14 Cupin domain - - - 0.000000000000000000000000000000000000000000000005886 176.0
CMS2_k127_732836_15 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000001926 181.0
CMS2_k127_732836_16 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000003079 147.0
CMS2_k127_732836_17 - - - - 0.000000000000000000000000000004529 128.0
CMS2_k127_732836_18 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000004227 114.0
CMS2_k127_732836_19 Protein of unknown function (DUF1272) K09984 - - 0.000000000000000000006597 93.0
CMS2_k127_732836_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 577.0
CMS2_k127_732836_20 toxin-antitoxin pair type II binding - - - 0.0000000000003138 77.0
CMS2_k127_732836_3 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006819 489.0
CMS2_k127_732836_4 MlrC C-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 325.0
CMS2_k127_732836_5 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002847 278.0
CMS2_k127_732836_6 Enoyl-CoA hydratase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000378 272.0
CMS2_k127_732836_7 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008232 267.0
CMS2_k127_732836_8 Biotin carboxylase C-terminal domain K01968 - 6.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000473 261.0
CMS2_k127_732836_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001188 248.0
CMS2_k127_734093_0 Putative beta-barrel porin 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 582.0
CMS2_k127_734093_1 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 488.0
CMS2_k127_734093_10 Transcription regulator MerR DNA binding K19591 - - 0.000000000000000000000000000000000000000000002288 168.0
CMS2_k127_734093_11 - - - - 0.00000000000000000000000000000000000002034 153.0
CMS2_k127_734093_12 COG2885 outer membrane protein and related peptidoglycan-associated (lipo)proteins - - - 0.0000000000000003367 92.0
CMS2_k127_734093_13 - - - - 0.00000000000005178 82.0
CMS2_k127_734093_2 carboxylase K01968 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 424.0
CMS2_k127_734093_3 flagellar motor protein K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 383.0
CMS2_k127_734093_4 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 364.0
CMS2_k127_734093_5 MotA TolQ ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 342.0
CMS2_k127_734093_6 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 310.0
CMS2_k127_734093_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005977 274.0
CMS2_k127_734093_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000009874 233.0
CMS2_k127_734093_9 Domain of unknown function (DUF4396) - - - 0.0000000000000000000000000000000000000000000000000000000001825 207.0
CMS2_k127_762913_0 Formate dehydrogenase subunit alpha - - - 0.0 1449.0
CMS2_k127_762913_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 5.056e-308 952.0
CMS2_k127_762913_10 transport system, periplasmic component K02035 - - 6.898e-209 661.0
CMS2_k127_762913_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.132e-208 655.0
CMS2_k127_762913_12 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 1.655e-203 650.0
CMS2_k127_762913_13 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 9.795e-198 621.0
CMS2_k127_762913_14 Spermidine putrescine-binding periplasmic protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 604.0
CMS2_k127_762913_15 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006916 570.0
CMS2_k127_762913_16 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009721 567.0
CMS2_k127_762913_17 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 544.0
CMS2_k127_762913_18 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 514.0
CMS2_k127_762913_19 Fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 495.0
CMS2_k127_762913_2 Dehydrogenase K00122 - 1.17.1.9 5.549e-281 872.0
CMS2_k127_762913_20 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 498.0
CMS2_k127_762913_21 TOBE domain K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 467.0
CMS2_k127_762913_22 PFAM Alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 459.0
CMS2_k127_762913_23 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009749 448.0
CMS2_k127_762913_24 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 484.0
CMS2_k127_762913_25 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 442.0
CMS2_k127_762913_26 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 442.0
CMS2_k127_762913_27 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 415.0
CMS2_k127_762913_28 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 398.0
CMS2_k127_762913_29 Biotin carboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 407.0
CMS2_k127_762913_3 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 5.316e-257 803.0
CMS2_k127_762913_30 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 401.0
CMS2_k127_762913_31 Peptidase family U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 359.0
CMS2_k127_762913_32 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 352.0
CMS2_k127_762913_33 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 346.0
CMS2_k127_762913_34 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 347.0
CMS2_k127_762913_35 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 315.0
CMS2_k127_762913_36 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 313.0
CMS2_k127_762913_37 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 293.0
CMS2_k127_762913_38 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004347 309.0
CMS2_k127_762913_39 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046,K00065 - 1.1.1.127,1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000002825 269.0
CMS2_k127_762913_4 FAD binding domain K05712 - 1.14.13.127 6.924e-243 762.0
CMS2_k127_762913_40 peptidase U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001763 267.0
CMS2_k127_762913_41 Dehydrogenases with different specificities (Related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003935 247.0
CMS2_k127_762913_42 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000000000000000002165 242.0
CMS2_k127_762913_43 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000003224 223.0
CMS2_k127_762913_44 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000314 200.0
CMS2_k127_762913_45 TIGRFAM death-on-curing family protein K07341 - - 0.00000000000000000000000000000000000000000000000000001234 191.0
CMS2_k127_762913_46 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000001003 176.0
CMS2_k127_762913_47 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000002656 137.0
CMS2_k127_762913_48 - - - - 0.0000000000000000000000004102 106.0
CMS2_k127_762913_49 Protein of unknown function (DUF2783) - - - 0.00000000000000000000009891 98.0
CMS2_k127_762913_5 Belongs to the ABC transporter superfamily - - - 1.741e-242 760.0
CMS2_k127_762913_50 - - - - 0.00000000000000000003618 100.0
CMS2_k127_762913_51 Histidine kinase - - - 0.0000000005316 70.0
CMS2_k127_762913_6 amidohydrolase K12941 - - 2.957e-237 745.0
CMS2_k127_762913_7 Protein conserved in bacteria K07793 - - 4.626e-235 736.0
CMS2_k127_762913_8 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 1.75e-232 732.0
CMS2_k127_762913_9 Hydrolase CocE NonD family K06978 - - 3.838e-212 668.0
CMS2_k127_790130_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1128.0
CMS2_k127_790130_1 Tripartite tricarboxylate transporter TctB family - - - 3.132e-296 922.0
CMS2_k127_790130_10 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K13039 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000003119 237.0
CMS2_k127_790130_11 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000003484 228.0
CMS2_k127_790130_12 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004841 225.0
CMS2_k127_790130_13 transmembrane signaling receptor activity - - - 0.00000000000000000000000000000000000000000003734 186.0
CMS2_k127_790130_14 AsnC family K03719 - - 0.00000000000000000000000000000000000000003469 156.0
CMS2_k127_790130_15 metalloprotease - - - 0.00000000000000000000000000000000000000003718 162.0
CMS2_k127_790130_16 LysE type translocator - - - 0.000000000000000000000000000000000007666 149.0
CMS2_k127_790130_17 - - - - 0.00000000000000000000000000000002096 138.0
CMS2_k127_790130_18 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000002641 127.0
CMS2_k127_790130_19 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000000000000000000687 128.0
CMS2_k127_790130_2 FAD binding domain - - - 1.323e-253 789.0
CMS2_k127_790130_20 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000007668 132.0
CMS2_k127_790130_21 COG0457 FOG TPR repeat - - - 0.0000000000000000000002069 111.0
CMS2_k127_790130_22 Protein of unknown function (DUF2937) - - - 0.0000000000004626 77.0
CMS2_k127_790130_3 Cobalamin biosynthesis protein CobT K09883 - 6.6.1.2 2.257e-217 691.0
CMS2_k127_790130_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 568.0
CMS2_k127_790130_5 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 422.0
CMS2_k127_790130_6 PrpF protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 410.0
CMS2_k127_790130_7 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 317.0
CMS2_k127_790130_8 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 291.0
CMS2_k127_790130_9 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001962 251.0
CMS2_k127_798189_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 458.0
CMS2_k127_798189_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 426.0
CMS2_k127_798189_10 DNA repair protein MmcB-like - - - 0.0000000000000000000000000000000000000001188 154.0
CMS2_k127_798189_11 Cobalamin synthesis protein cobW C-terminal domain K02234 - - 0.000000000002177 68.0
CMS2_k127_798189_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006432 278.0
CMS2_k127_798189_3 PFAM Response regulator receiver domain K15012 GO:0000156,GO:0000160,GO:0003674,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002303 265.0
CMS2_k127_798189_4 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000003272 241.0
CMS2_k127_798189_5 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000004761 232.0
CMS2_k127_798189_6 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000000000000000003794 218.0
CMS2_k127_798189_7 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000008236 205.0
CMS2_k127_798189_8 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000007032 181.0
CMS2_k127_798189_9 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000005542 158.0
CMS2_k127_80235_0 Molecular chaperone. Has ATPase activity K04079 - - 3.112e-255 801.0
CMS2_k127_80235_1 membrane - - - 1.386e-204 649.0
CMS2_k127_80235_10 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008348 254.0
CMS2_k127_80235_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000001259 239.0
CMS2_k127_80235_12 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000005434 207.0
CMS2_k127_80235_13 Protein of unknown function (DUF1223) - - - 0.0000000000000000000000000000000000000000000000001283 185.0
CMS2_k127_80235_14 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000009255 177.0
CMS2_k127_80235_17 Protein of unknown function (DUF1778) - - - 0.000000000000000000000000000002156 123.0
CMS2_k127_80235_2 CoA binding domain - - - 1.338e-201 650.0
CMS2_k127_80235_3 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 456.0
CMS2_k127_80235_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 460.0
CMS2_k127_80235_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 396.0
CMS2_k127_80235_6 Spermidine putrescine-binding periplasmic protein K02055 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 377.0
CMS2_k127_80235_7 ABC-type spermidine putrescine transport system, permease component I K02054,K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 366.0
CMS2_k127_80235_8 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 330.0
CMS2_k127_80235_9 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000004029 261.0
CMS2_k127_868863_0 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 481.0