Overview

ID MAG00418
Name CMS2_bin.26
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family SG8-39
Genus JAABQT01
Species JAABQT01 sp035459025
Assembly information
Completeness (%) 91.03
Contamination (%) 3.54
GC content (%) 70.0
N50 (bp) 19,409
Genome size (bp) 3,280,434

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3367

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1018068_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.0 1032.0
CMS2_k127_1018068_1 Heavy-metal-associated domain - - - 7.851e-273 861.0
CMS2_k127_1018068_10 Multi-copper - - - 0.0000000000000000000000000000000000000000009191 162.0
CMS2_k127_1018068_11 - - - - 0.0000000000000000000000000000002426 128.0
CMS2_k127_1018068_12 Protein of unknown function (DUF2933) - - - 0.000000000000000007603 85.0
CMS2_k127_1018068_13 efflux transmembrane transporter activity K02004 - - 0.00000000000001341 85.0
CMS2_k127_1018068_14 mercury ion transmembrane transporter activity K01533,K01534,K07213 - 3.6.3.3,3.6.3.4,3.6.3.5 0.0000000000004391 72.0
CMS2_k127_1018068_15 FtsX-like permease family K02004 - - 0.0008306 51.0
CMS2_k127_1018068_2 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 376.0
CMS2_k127_1018068_3 COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002561 282.0
CMS2_k127_1018068_4 Cytochrome c biogenesis protein K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001547 281.0
CMS2_k127_1018068_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000004466 207.0
CMS2_k127_1018068_6 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000001047 184.0
CMS2_k127_1018068_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000001053 177.0
CMS2_k127_1018068_8 helix_turn_helix, mercury resistance K19591,K19592 - - 0.0000000000000000000000000000000000000000000001566 184.0
CMS2_k127_1018068_9 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000001457 165.0
CMS2_k127_104205_0 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 527.0
CMS2_k127_104205_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 326.0
CMS2_k127_104205_2 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004741 272.0
CMS2_k127_104205_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009794 261.0
CMS2_k127_104205_4 MMPL family - - - 0.0000000000000000000000000000000000000000000000000000000000005707 218.0
CMS2_k127_104205_5 dehydratase - - - 0.0000000000000000000000000000000000000000002363 172.0
CMS2_k127_104205_6 NAD dependent epimerase/dehydratase family K00059 - 1.1.1.100 0.000000000000000000255 90.0
CMS2_k127_1054960_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 1.968e-244 788.0
CMS2_k127_1054960_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 4.788e-237 739.0
CMS2_k127_1054960_10 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 361.0
CMS2_k127_1054960_11 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 342.0
CMS2_k127_1054960_12 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 319.0
CMS2_k127_1054960_13 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 302.0
CMS2_k127_1054960_14 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007147 289.0
CMS2_k127_1054960_15 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000002764 244.0
CMS2_k127_1054960_16 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000002008 99.0
CMS2_k127_1054960_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 5.91e-221 691.0
CMS2_k127_1054960_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 559.0
CMS2_k127_1054960_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 559.0
CMS2_k127_1054960_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 547.0
CMS2_k127_1054960_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003023 434.0
CMS2_k127_1054960_7 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 425.0
CMS2_k127_1054960_8 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 348.0
CMS2_k127_1054960_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 357.0
CMS2_k127_1062780_0 COG0471 Di- and tricarboxylate transporters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 571.0
CMS2_k127_1062780_1 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 556.0
CMS2_k127_1062780_10 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000004293 148.0
CMS2_k127_1062780_11 - - - - 0.0000000000000000000000001447 116.0
CMS2_k127_1062780_2 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 439.0
CMS2_k127_1062780_3 alcohol dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 415.0
CMS2_k127_1062780_4 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 408.0
CMS2_k127_1062780_5 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 358.0
CMS2_k127_1062780_6 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 328.0
CMS2_k127_1062780_7 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 336.0
CMS2_k127_1062780_8 Permeases of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 306.0
CMS2_k127_1062780_9 Ankyrin repeats (3 copies) K06867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005171 269.0
CMS2_k127_1080988_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 6.711e-237 758.0
CMS2_k127_1080988_1 ABC-type Fe3 transport system, permease component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 569.0
CMS2_k127_1080988_10 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000000003391 137.0
CMS2_k127_1080988_11 Uncharacterized ACR, COG1678 K07735 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000007718 83.0
CMS2_k127_1080988_12 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000001228 69.0
CMS2_k127_1080988_2 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 499.0
CMS2_k127_1080988_3 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 352.0
CMS2_k127_1080988_4 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 334.0
CMS2_k127_1080988_5 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 335.0
CMS2_k127_1080988_6 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 316.0
CMS2_k127_1080988_7 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000003992 217.0
CMS2_k127_1080988_8 PFAM NLP P60 protein - - - 0.000000000000000000000000000000000000000000349 162.0
CMS2_k127_1080988_9 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000000000000000000006734 171.0
CMS2_k127_1099953_0 type II secretion system protein E K02283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 559.0
CMS2_k127_1099953_1 type II and III secretion system protein K02280 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 355.0
CMS2_k127_1099953_2 Type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008953 246.0
CMS2_k127_1099953_3 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000000000000000000000000000000000000000000000000000000000009567 245.0
CMS2_k127_1099953_4 Type II secretion system K12510 - - 0.00000000000000000000000000000000000000000000001789 198.0
CMS2_k127_1099953_5 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000005954 94.0
CMS2_k127_1143581_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1324.0
CMS2_k127_1143581_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1236.0
CMS2_k127_1143581_10 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 464.0
CMS2_k127_1143581_11 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 457.0
CMS2_k127_1143581_12 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 447.0
CMS2_k127_1143581_13 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 439.0
CMS2_k127_1143581_14 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 444.0
CMS2_k127_1143581_15 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 443.0
CMS2_k127_1143581_16 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 426.0
CMS2_k127_1143581_17 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 417.0
CMS2_k127_1143581_18 Dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 405.0
CMS2_k127_1143581_19 PFAM AAA ATPase central domain protein K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 406.0
CMS2_k127_1143581_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1183.0
CMS2_k127_1143581_20 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 380.0
CMS2_k127_1143581_21 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 376.0
CMS2_k127_1143581_22 His Kinase A (phospho-acceptor) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 353.0
CMS2_k127_1143581_23 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 339.0
CMS2_k127_1143581_24 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 335.0
CMS2_k127_1143581_25 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 316.0
CMS2_k127_1143581_26 Belongs to the RNA methyltransferase TrmD family K00554 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 316.0
CMS2_k127_1143581_27 PFAM molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 308.0
CMS2_k127_1143581_28 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005349 280.0
CMS2_k127_1143581_29 molybdenum cofactor K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000996 273.0
CMS2_k127_1143581_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.164e-201 634.0
CMS2_k127_1143581_30 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001708 262.0
CMS2_k127_1143581_31 HpcH/HpaI aldolase/citrate lyase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003673 275.0
CMS2_k127_1143581_32 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000002894 239.0
CMS2_k127_1143581_33 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000003827 255.0
CMS2_k127_1143581_34 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002528 239.0
CMS2_k127_1143581_35 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000002055 217.0
CMS2_k127_1143581_36 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000003934 205.0
CMS2_k127_1143581_37 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000009949 197.0
CMS2_k127_1143581_38 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000002635 199.0
CMS2_k127_1143581_39 PFAM NUDIX hydrolase K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000001584 199.0
CMS2_k127_1143581_4 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 563.0
CMS2_k127_1143581_40 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000003309 202.0
CMS2_k127_1143581_41 carbon monoxide dehydrogenase K09386 - - 0.0000000000000000000000000000000000000000000000000001819 192.0
CMS2_k127_1143581_42 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000002114 201.0
CMS2_k127_1143581_43 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000006016 184.0
CMS2_k127_1143581_44 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000836 179.0
CMS2_k127_1143581_45 MobA-Related Protein K07141 - 2.7.7.76 0.00000000000000000000000000000000000000001296 165.0
CMS2_k127_1143581_46 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000009872 155.0
CMS2_k127_1143581_47 Etoposide-induced protein 2.4 (EI24) - - - 0.000000000000000000000000000000000000000175 174.0
CMS2_k127_1143581_48 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000000000127 150.0
CMS2_k127_1143581_49 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000000000001642 147.0
CMS2_k127_1143581_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 561.0
CMS2_k127_1143581_50 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000001223 140.0
CMS2_k127_1143581_51 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000001938 125.0
CMS2_k127_1143581_52 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000004129 128.0
CMS2_k127_1143581_53 - - - - 0.000000000000000000000000000002356 132.0
CMS2_k127_1143581_54 Modulates RecA activity K03565 - - 0.0000000000000000000002322 106.0
CMS2_k127_1143581_56 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000442 66.0
CMS2_k127_1143581_6 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 582.0
CMS2_k127_1143581_7 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 542.0
CMS2_k127_1143581_8 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 539.0
CMS2_k127_1143581_9 With GlrK is part of a two-component signal transduction system regulating glmY K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 527.0
CMS2_k127_1148876_0 Isocitrate lyase K01637 - 4.1.3.1 3.684e-224 702.0
CMS2_k127_1148876_1 twitching motility protein K02670 - - 3.711e-206 645.0
CMS2_k127_1148876_10 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 370.0
CMS2_k127_1148876_11 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 363.0
CMS2_k127_1148876_12 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 346.0
CMS2_k127_1148876_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 337.0
CMS2_k127_1148876_14 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 299.0
CMS2_k127_1148876_15 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006493 264.0
CMS2_k127_1148876_16 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004621 283.0
CMS2_k127_1148876_17 VanZ like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002215 256.0
CMS2_k127_1148876_18 Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000000000004507 213.0
CMS2_k127_1148876_19 Alpha beta K07018 - - 0.000000000000000000000000000000000000000000000000000006161 218.0
CMS2_k127_1148876_2 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 2.272e-205 657.0
CMS2_k127_1148876_20 Tim44 - - - 0.000000000000000000000000000000000000000000000003046 184.0
CMS2_k127_1148876_21 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000002358 178.0
CMS2_k127_1148876_22 Ferredoxin - - - 0.0000000000000000000000000000000000000000000005937 167.0
CMS2_k127_1148876_23 Histidine triad (HIT) - - - 0.000000000000000000000000000000000000000000002749 167.0
CMS2_k127_1148876_24 Predicted membrane protein (DUF2214) K08983 - - 0.00000000000000000000000000000000000000335 150.0
CMS2_k127_1148876_25 integral membrane protein K02221 - - 0.000000000000000000000000000000000001141 155.0
CMS2_k127_1148876_26 protein conserved in bacteria K03690 - - 0.000000000000000000000000000001365 129.0
CMS2_k127_1148876_27 FAD linked oxidase domain protein - - - 0.00000000000000000000000000158 113.0
CMS2_k127_1148876_28 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.000000000000000000000002314 104.0
CMS2_k127_1148876_3 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.255e-204 657.0
CMS2_k127_1148876_30 - - - - 0.0000000000000000000003238 101.0
CMS2_k127_1148876_31 - - - - 0.000000000007392 66.0
CMS2_k127_1148876_4 twitching motility protein K02669 - - 1.827e-197 625.0
CMS2_k127_1148876_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 560.0
CMS2_k127_1148876_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 460.0
CMS2_k127_1148876_7 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 430.0
CMS2_k127_1148876_8 Alpha/beta hydrolase of unknown function (DUF900) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 398.0
CMS2_k127_1148876_9 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 401.0
CMS2_k127_1157407_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 1.067e-261 833.0
CMS2_k127_1157407_1 poly(R)-hydroxyalkanoic acid synthase K03821 - - 2.526e-252 808.0
CMS2_k127_1157407_10 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 328.0
CMS2_k127_1157407_11 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 307.0
CMS2_k127_1157407_12 PFAM Enoyl-CoA hydratase isomerase K13766,K15312 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 294.0
CMS2_k127_1157407_13 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004515 273.0
CMS2_k127_1157407_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004633 272.0
CMS2_k127_1157407_15 carboxylase K01968 - 6.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000008089 240.0
CMS2_k127_1157407_16 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000297 197.0
CMS2_k127_1157407_17 cell division protein - - - 0.00000000000000000000000000000000000000000001083 171.0
CMS2_k127_1157407_18 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000006339 164.0
CMS2_k127_1157407_19 Transcriptional regulator - - - 0.00000000000000000000000000000000000009536 145.0
CMS2_k127_1157407_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.259e-228 719.0
CMS2_k127_1157407_20 thiolester hydrolase activity K17362 - - 0.0000000000000000000000002443 121.0
CMS2_k127_1157407_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.038e-216 691.0
CMS2_k127_1157407_4 Belongs to the thiolase family K00626 - 2.3.1.9 3.184e-195 617.0
CMS2_k127_1157407_5 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 616.0
CMS2_k127_1157407_6 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 531.0
CMS2_k127_1157407_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 509.0
CMS2_k127_1157407_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007819 384.0
CMS2_k127_1157407_9 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 347.0
CMS2_k127_1171739_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 3.37e-287 894.0
CMS2_k127_1171739_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.971e-197 625.0
CMS2_k127_1171739_10 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 400.0
CMS2_k127_1171739_11 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 408.0
CMS2_k127_1171739_12 pfkB family carbohydrate kinase K21344 - 2.7.1.167 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 357.0
CMS2_k127_1171739_13 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 353.0
CMS2_k127_1171739_14 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 315.0
CMS2_k127_1171739_15 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000005798 242.0
CMS2_k127_1171739_16 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000002194 168.0
CMS2_k127_1171739_17 Belongs to the BI1 family K19416 - - 0.0000000000000001134 80.0
CMS2_k127_1171739_18 Lipopolysaccharide assembly protein A domain K08992 - - 0.000000000000001154 83.0
CMS2_k127_1171739_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 545.0
CMS2_k127_1171739_3 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 529.0
CMS2_k127_1171739_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 512.0
CMS2_k127_1171739_5 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 498.0
CMS2_k127_1171739_6 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 513.0
CMS2_k127_1171739_7 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 500.0
CMS2_k127_1171739_8 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 455.0
CMS2_k127_1171739_9 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 432.0
CMS2_k127_1187123_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 575.0
CMS2_k127_1187123_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 374.0
CMS2_k127_1187123_2 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000307 229.0
CMS2_k127_1187123_3 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001001 224.0
CMS2_k127_1187123_4 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000006867 145.0
CMS2_k127_1187123_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000005566 108.0
CMS2_k127_1188258_0 Spermidine putrescine ABC transporter substrate-binding protein K02055 GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 609.0
CMS2_k127_1188258_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 358.0
CMS2_k127_1188258_10 Uncharacterized ACR, COG1678 - - - 0.000000000000000000000006149 109.0
CMS2_k127_1188258_11 Uncharacterized ACR, COG1678 - - - 0.000000000000000000000464 108.0
CMS2_k127_1188258_12 alpha/beta hydrolase fold - - - 0.0000000000000000000009181 101.0
CMS2_k127_1188258_13 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000001861 58.0
CMS2_k127_1188258_2 ChaC-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002923 286.0
CMS2_k127_1188258_3 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000003455 241.0
CMS2_k127_1188258_4 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002057 228.0
CMS2_k127_1188258_5 - - - - 0.000000000000000000000000000000000000000000000000000024 188.0
CMS2_k127_1188258_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000007754 171.0
CMS2_k127_1188258_7 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000008316 151.0
CMS2_k127_1188258_8 MreB/Mbl protein K03569 - - 0.000000000000000000000000000000000001658 147.0
CMS2_k127_1188258_9 TOBE domain K02052 - - 0.00000000000000000000000000000004322 129.0
CMS2_k127_1195111_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 8.214e-284 880.0
CMS2_k127_1208037_0 PFAM CoA-binding domain protein - - - 8.955e-221 725.0
CMS2_k127_1208037_1 PFAM carboxyl transferase - - - 2.963e-218 707.0
CMS2_k127_1208037_10 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 329.0
CMS2_k127_1208037_11 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002357 287.0
CMS2_k127_1208037_12 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000002246 271.0
CMS2_k127_1208037_13 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003358 264.0
CMS2_k127_1208037_14 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000002363 224.0
CMS2_k127_1208037_15 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000008655 183.0
CMS2_k127_1208037_16 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.000000000000000000000000000000000000000000000003633 176.0
CMS2_k127_1208037_17 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000003708 163.0
CMS2_k127_1208037_18 PFAM diacylglycerol kinase catalytic region - - - 0.00000000000000000000000000000000009896 142.0
CMS2_k127_1208037_19 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.000000000000000000000000000002042 133.0
CMS2_k127_1208037_2 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 1.195e-210 666.0
CMS2_k127_1208037_20 Protein of unknown function (DUF3617) - - - 0.000000000000000000000002598 115.0
CMS2_k127_1208037_21 Allophanate hydrolase subunit 2 K01941 - 6.3.4.6 0.00006026 50.0
CMS2_k127_1208037_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 581.0
CMS2_k127_1208037_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 561.0
CMS2_k127_1208037_5 thiolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 546.0
CMS2_k127_1208037_6 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 522.0
CMS2_k127_1208037_7 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 469.0
CMS2_k127_1208037_8 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 432.0
CMS2_k127_1208037_9 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 389.0
CMS2_k127_1217134_0 TatD related DNase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 513.0
CMS2_k127_1217134_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 477.0
CMS2_k127_1217134_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 441.0
CMS2_k127_1217134_3 Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 416.0
CMS2_k127_1217134_4 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 329.0
CMS2_k127_1217134_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 297.0
CMS2_k127_1217134_6 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006413 293.0
CMS2_k127_1217134_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001187 266.0
CMS2_k127_1217134_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00004824 51.0
CMS2_k127_1217134_9 Transmembrane family 220, helix - - - 0.0002497 53.0
CMS2_k127_1220041_0 belongs to the aldehyde dehydrogenase family K00137 - 1.2.1.19 1.179e-239 762.0
CMS2_k127_1220041_1 COG0044 Dihydroorotase and related cyclic amidohydrolases - - - 2.352e-198 629.0
CMS2_k127_1220041_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 347.0
CMS2_k127_1220041_11 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 320.0
CMS2_k127_1220041_12 Asp/Glu/Hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 299.0
CMS2_k127_1220041_13 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 292.0
CMS2_k127_1220041_14 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007171 270.0
CMS2_k127_1220041_15 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004482 291.0
CMS2_k127_1220041_16 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000008685 193.0
CMS2_k127_1220041_17 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000006839 197.0
CMS2_k127_1220041_2 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 601.0
CMS2_k127_1220041_3 Belongs to the ABC transporter superfamily K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 429.0
CMS2_k127_1220041_4 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 429.0
CMS2_k127_1220041_5 ABC transporter (Permease K02054 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 423.0
CMS2_k127_1220041_6 Binding-protein-dependent transport system inner membrane component K02053,K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 391.0
CMS2_k127_1220041_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 379.0
CMS2_k127_1220041_8 ABC transporter K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 362.0
CMS2_k127_1220041_9 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 350.0
CMS2_k127_1240972_0 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 9.448e-306 974.0
CMS2_k127_1240972_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.679e-231 721.0
CMS2_k127_1240972_10 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 337.0
CMS2_k127_1240972_11 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 321.0
CMS2_k127_1240972_12 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 297.0
CMS2_k127_1240972_13 esterase K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000012 291.0
CMS2_k127_1240972_14 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007908 277.0
CMS2_k127_1240972_15 50S ribosomal protein L4 K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001269 281.0
CMS2_k127_1240972_16 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001831 260.0
CMS2_k127_1240972_17 Cysteine - - - 0.000000000000000000000000000000000000000000000000000000000000000000005548 258.0
CMS2_k127_1240972_18 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000002188 233.0
CMS2_k127_1240972_19 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000003389 226.0
CMS2_k127_1240972_2 AMP-binding enzyme K12508 - 6.2.1.34 9.776e-222 701.0
CMS2_k127_1240972_20 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000008545 224.0
CMS2_k127_1240972_21 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000006053 209.0
CMS2_k127_1240972_22 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000002986 202.0
CMS2_k127_1240972_23 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000001188 194.0
CMS2_k127_1240972_24 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000000886 190.0
CMS2_k127_1240972_25 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000001946 189.0
CMS2_k127_1240972_26 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000000002497 180.0
CMS2_k127_1240972_27 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000007667 169.0
CMS2_k127_1240972_28 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000006729 160.0
CMS2_k127_1240972_29 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000001653 150.0
CMS2_k127_1240972_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 542.0
CMS2_k127_1240972_30 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000000000000000007294 139.0
CMS2_k127_1240972_31 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000005833 142.0
CMS2_k127_1240972_32 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000005625 126.0
CMS2_k127_1240972_33 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000002453 91.0
CMS2_k127_1240972_34 Ribosomal protein L30p/L7e K02907 - - 0.0000000000000004244 91.0
CMS2_k127_1240972_35 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000006926 77.0
CMS2_k127_1240972_36 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000009922 68.0
CMS2_k127_1240972_4 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 526.0
CMS2_k127_1240972_5 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 523.0
CMS2_k127_1240972_6 hydroxypyruvate reductase K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 485.0
CMS2_k127_1240972_7 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 449.0
CMS2_k127_1240972_8 indolepyruvate oxidoreductase subunit B K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 478.0
CMS2_k127_1240972_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 336.0
CMS2_k127_1314057_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1079.0
CMS2_k127_1314057_1 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 2.847e-287 897.0
CMS2_k127_1314057_10 13-prostaglandin reductase activity K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 400.0
CMS2_k127_1314057_11 Nitronate monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 433.0
CMS2_k127_1314057_12 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 372.0
CMS2_k127_1314057_13 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 364.0
CMS2_k127_1314057_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 352.0
CMS2_k127_1314057_15 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 331.0
CMS2_k127_1314057_16 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 329.0
CMS2_k127_1314057_17 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006915 331.0
CMS2_k127_1314057_18 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 306.0
CMS2_k127_1314057_19 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002967 268.0
CMS2_k127_1314057_2 Aldehyde dehydrogenase K00128,K00130 - 1.2.1.3,1.2.1.8 1.488e-203 666.0
CMS2_k127_1314057_20 - - - - 0.000000000000000000000000000000000000000000000000000000004437 209.0
CMS2_k127_1314057_21 Protein conserved in bacteria - - - 0.0000000000000000000001491 113.0
CMS2_k127_1314057_22 Thioesterase superfamily protein - - - 0.00000000000000000001152 105.0
CMS2_k127_1314057_23 Hemolysin-type calcium-binding region - - - 0.00000000000000002154 96.0
CMS2_k127_1314057_24 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000003528 67.0
CMS2_k127_1314057_3 CoA binding domain - - - 2.379e-201 661.0
CMS2_k127_1314057_4 Belongs to the thiolase family K00626 - 2.3.1.9 2.014e-197 621.0
CMS2_k127_1314057_5 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 593.0
CMS2_k127_1314057_6 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000988 565.0
CMS2_k127_1314057_7 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008089 500.0
CMS2_k127_1314057_8 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 451.0
CMS2_k127_1314057_9 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 417.0
CMS2_k127_1319313_0 FAD linked oxidase domain protein K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 548.0
CMS2_k127_1319313_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 482.0
CMS2_k127_1319313_2 luciferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 374.0
CMS2_k127_1319313_3 transport system fused permease components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000118 282.0
CMS2_k127_1319313_4 2-Keto-4-pentenoate hydratase - - - 0.00000000000000000000000000000000000000000000000000000000002595 215.0
CMS2_k127_1319313_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000003975 135.0
CMS2_k127_1319313_6 Ankyrin repeat - - - 0.0000000000000000000004273 108.0
CMS2_k127_1319313_7 Protein of unknown function (DUF1223) - - - 0.00000000000131 71.0
CMS2_k127_1319313_8 DNA-sulfur modification-associated - - - 0.000002372 59.0
CMS2_k127_1361292_0 Domain of unknown function (DUF3394) - - - 1.487e-303 944.0
CMS2_k127_1361292_1 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 2.249e-271 842.0
CMS2_k127_1361292_10 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.0000000000000000000000000000000002122 141.0
CMS2_k127_1361292_11 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.00000000000000000000000003473 122.0
CMS2_k127_1361292_2 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 539.0
CMS2_k127_1361292_3 Fumarate hydratase (Fumerase) K01677,K03779 - 4.2.1.2,4.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 463.0
CMS2_k127_1361292_4 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 459.0
CMS2_k127_1361292_5 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 379.0
CMS2_k127_1361292_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 340.0
CMS2_k127_1361292_7 Fumarase C-terminus K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 335.0
CMS2_k127_1361292_8 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K16846 - 4.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001544 278.0
CMS2_k127_1361292_9 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000000004746 190.0
CMS2_k127_1388401_0 PFAM fumarate lyase K01756,K01857 - 4.3.2.2,5.5.1.2 1.01e-215 676.0
CMS2_k127_1388401_1 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000002755 216.0
CMS2_k127_1388401_2 Nodulation protein S (NodS) - - - 0.000007325 57.0
CMS2_k127_1414152_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1478.0
CMS2_k127_1414152_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1129.0
CMS2_k127_1414152_10 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.257e-234 737.0
CMS2_k127_1414152_100 - - - - 0.00000000000000007621 83.0
CMS2_k127_1414152_103 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000003905 72.0
CMS2_k127_1414152_11 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 6.525e-234 744.0
CMS2_k127_1414152_12 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.526e-227 713.0
CMS2_k127_1414152_13 AMP-binding enzyme C-terminal domain K00666 - - 4.168e-227 715.0
CMS2_k127_1414152_14 Participates in both transcription termination and antitermination K02600 - - 1.902e-222 702.0
CMS2_k127_1414152_15 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.396e-215 682.0
CMS2_k127_1414152_16 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 8.977e-215 683.0
CMS2_k127_1414152_17 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 4.548e-202 646.0
CMS2_k127_1414152_18 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 609.0
CMS2_k127_1414152_19 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 590.0
CMS2_k127_1414152_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1028.0
CMS2_k127_1414152_20 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 550.0
CMS2_k127_1414152_21 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 524.0
CMS2_k127_1414152_22 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 496.0
CMS2_k127_1414152_23 Periplasmic binding protein K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 489.0
CMS2_k127_1414152_24 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 491.0
CMS2_k127_1414152_25 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 467.0
CMS2_k127_1414152_26 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 466.0
CMS2_k127_1414152_27 twitching motility protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009169 463.0
CMS2_k127_1414152_28 D-amino acid dehydrogenase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 455.0
CMS2_k127_1414152_29 Branched-chain amino acid transport system permease K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 464.0
CMS2_k127_1414152_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1017.0
CMS2_k127_1414152_30 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 430.0
CMS2_k127_1414152_31 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 430.0
CMS2_k127_1414152_32 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 419.0
CMS2_k127_1414152_33 L-phenylalanine transmembrane transporter activity K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 415.0
CMS2_k127_1414152_34 amino acid K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 404.0
CMS2_k127_1414152_35 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 405.0
CMS2_k127_1414152_36 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 395.0
CMS2_k127_1414152_37 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 403.0
CMS2_k127_1414152_38 Psort location Cytoplasmic, score 8.96 K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 389.0
CMS2_k127_1414152_39 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 381.0
CMS2_k127_1414152_4 Required for chromosome condensation and partitioning K03529 - - 6e-323 1026.0
CMS2_k127_1414152_40 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 372.0
CMS2_k127_1414152_41 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 372.0
CMS2_k127_1414152_42 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 386.0
CMS2_k127_1414152_43 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 366.0
CMS2_k127_1414152_44 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 361.0
CMS2_k127_1414152_45 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 357.0
CMS2_k127_1414152_46 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 354.0
CMS2_k127_1414152_47 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 347.0
CMS2_k127_1414152_48 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 347.0
CMS2_k127_1414152_49 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 345.0
CMS2_k127_1414152_5 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 3.27e-321 1004.0
CMS2_k127_1414152_50 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 336.0
CMS2_k127_1414152_51 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005054 341.0
CMS2_k127_1414152_52 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 323.0
CMS2_k127_1414152_53 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 320.0
CMS2_k127_1414152_54 SMART phosphoesterase PHP domain protein K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 329.0
CMS2_k127_1414152_55 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 321.0
CMS2_k127_1414152_56 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 326.0
CMS2_k127_1414152_57 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 322.0
CMS2_k127_1414152_58 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 332.0
CMS2_k127_1414152_59 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 299.0
CMS2_k127_1414152_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 3.28e-288 903.0
CMS2_k127_1414152_60 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 300.0
CMS2_k127_1414152_61 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 287.0
CMS2_k127_1414152_62 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001745 281.0
CMS2_k127_1414152_63 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000046 276.0
CMS2_k127_1414152_64 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009499 272.0
CMS2_k127_1414152_65 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007173 267.0
CMS2_k127_1414152_66 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001538 269.0
CMS2_k127_1414152_67 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002208 269.0
CMS2_k127_1414152_68 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003461 262.0
CMS2_k127_1414152_69 Abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008122 272.0
CMS2_k127_1414152_7 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.13e-277 864.0
CMS2_k127_1414152_70 Belongs to the protein N5-glutamine methyltransferase family K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000004821 273.0
CMS2_k127_1414152_71 TRAP-type mannitol chloroaromatic compound transport system small permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004539 258.0
CMS2_k127_1414152_72 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001731 255.0
CMS2_k127_1414152_73 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000000004716 237.0
CMS2_k127_1414152_74 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000005333 241.0
CMS2_k127_1414152_75 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000000000000001068 222.0
CMS2_k127_1414152_76 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000004758 223.0
CMS2_k127_1414152_77 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000001914 207.0
CMS2_k127_1414152_78 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000006388 199.0
CMS2_k127_1414152_79 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000003044 204.0
CMS2_k127_1414152_8 Class II Aldolase and Adducin N-terminal domain - - - 6.205e-261 823.0
CMS2_k127_1414152_80 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000001484 196.0
CMS2_k127_1414152_81 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000003164 196.0
CMS2_k127_1414152_82 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000009396 201.0
CMS2_k127_1414152_83 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000195 186.0
CMS2_k127_1414152_84 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000005661 186.0
CMS2_k127_1414152_85 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000003425 185.0
CMS2_k127_1414152_86 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000006336 194.0
CMS2_k127_1414152_87 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000005066 179.0
CMS2_k127_1414152_88 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000004511 162.0
CMS2_k127_1414152_89 NIPSNAP - - - 0.000000000000000000000000000000000000000001736 159.0
CMS2_k127_1414152_9 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 1.012e-235 744.0
CMS2_k127_1414152_90 asparaginase K01424,K13051 GO:0003674,GO:0003824,GO:0004067,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008798,GO:0010467,GO:0016485,GO:0016540,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.19.5,3.5.1.1 0.00000000000000000000000000000000000001049 150.0
CMS2_k127_1414152_91 n-acetyltransferase - - - 0.00000000000000000000000000000000000002213 154.0
CMS2_k127_1414152_92 Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000006491 141.0
CMS2_k127_1414152_93 Ribosomal_S15 K02956 - - 0.00000000000000000000000000000004112 126.0
CMS2_k127_1414152_94 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000009252 134.0
CMS2_k127_1414152_95 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000006825 111.0
CMS2_k127_1414152_96 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000003807 94.0
CMS2_k127_1414152_97 Domain of unknown function (DUF4124) - - - 0.0000000000000000007817 93.0
CMS2_k127_1433202_0 Polyphosphate kinase middle domain K00937 - 2.7.4.1 0.0 1098.0
CMS2_k127_1433202_1 CHAD - - - 8.244e-217 684.0
CMS2_k127_1433202_2 Flagellar M-ring protein C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 610.0
CMS2_k127_1433202_3 FliG middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 465.0
CMS2_k127_1433202_4 Flagellar assembly protein FliH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 318.0
CMS2_k127_1433202_5 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003218 260.0
CMS2_k127_1433202_6 ATP synthase alpha/beta family, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002804 243.0
CMS2_k127_1445379_0 ATP cone domain K21636 - 1.1.98.6 0.0 1138.0
CMS2_k127_1445379_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 5.17e-205 654.0
CMS2_k127_1445379_10 transcriptional regulator AsnC family - - - 0.000000000000000000000000000000000000000000000000000000001737 211.0
CMS2_k127_1445379_11 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000003067 220.0
CMS2_k127_1445379_12 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000005974 185.0
CMS2_k127_1445379_13 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000002098 168.0
CMS2_k127_1445379_14 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000002926 158.0
CMS2_k127_1445379_15 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000000002683 123.0
CMS2_k127_1445379_16 Rubrerythrin - - - 0.00000000000000000000000000002838 133.0
CMS2_k127_1445379_17 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.0000000000000000000000000001726 117.0
CMS2_k127_1445379_18 radical SAM protein - - - 0.0000000000000000000000000006105 114.0
CMS2_k127_1445379_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 604.0
CMS2_k127_1445379_3 Cytochrome D1 heme domain K19345 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 513.0
CMS2_k127_1445379_4 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 489.0
CMS2_k127_1445379_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 407.0
CMS2_k127_1445379_6 COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 354.0
CMS2_k127_1445379_7 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 321.0
CMS2_k127_1445379_8 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 292.0
CMS2_k127_1445379_9 Vitamin k epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004036 263.0
CMS2_k127_1449975_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.11e-282 877.0
CMS2_k127_1449975_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000678 622.0
CMS2_k127_1449975_10 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 432.0
CMS2_k127_1449975_11 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 379.0
CMS2_k127_1449975_12 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 366.0
CMS2_k127_1449975_13 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009569 276.0
CMS2_k127_1449975_14 alginate biosynthesis protein AlgZ FimS K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006431 293.0
CMS2_k127_1449975_15 Alginate biosynthesis regulatory protein AlgR K08083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003407 264.0
CMS2_k127_1449975_16 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000002581 256.0
CMS2_k127_1449975_17 - - - - 0.00000000000000000000000000000000000000000000000127 179.0
CMS2_k127_1449975_18 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000005649 174.0
CMS2_k127_1449975_19 - - - - 0.00000000000000000000000000000000000000000000002681 171.0
CMS2_k127_1449975_2 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 576.0
CMS2_k127_1449975_20 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000008754 170.0
CMS2_k127_1449975_21 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000005061 166.0
CMS2_k127_1449975_22 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000004699 143.0
CMS2_k127_1449975_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 519.0
CMS2_k127_1449975_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 541.0
CMS2_k127_1449975_5 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 515.0
CMS2_k127_1449975_6 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 515.0
CMS2_k127_1449975_7 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 479.0
CMS2_k127_1449975_8 TIGRFAM type I secretion membrane fusion protein, HlyD K02022,K11003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 481.0
CMS2_k127_1449975_9 Haemolysin-type calcium binding protein related domain K01406 - 3.4.24.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 480.0
CMS2_k127_155776_0 Drug exporters of the RND superfamily K06994,K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 486.0
CMS2_k127_155776_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008927 456.0
CMS2_k127_155776_2 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 359.0
CMS2_k127_155776_3 Pfam:PNPOx_C K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007754 272.0
CMS2_k127_155776_4 pfam abc K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002073 247.0
CMS2_k127_155776_5 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000007247 133.0
CMS2_k127_155776_6 O-methyltransferase activity K05303 - - 0.0000000000000000000006285 100.0
CMS2_k127_1564766_0 chemotaxis K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 309.0
CMS2_k127_1564766_1 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000003303 188.0
CMS2_k127_1578920_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1478.0
CMS2_k127_1578920_1 4Fe-4S dicluster domain - - - 4.352e-236 753.0
CMS2_k127_1578920_10 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000527 223.0
CMS2_k127_1578920_11 Protein of unknown function (DUF3305) - - - 0.0000000000000000000000000000000000002077 145.0
CMS2_k127_1578920_12 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000004782 152.0
CMS2_k127_1578920_13 Mechanosensitive ion channel - - - 0.00000000000000000000000000004567 118.0
CMS2_k127_1578920_14 Protein of unknown function (DUF3306) - - - 0.00000000000000004234 92.0
CMS2_k127_1578920_15 - - - - 0.000000004062 66.0
CMS2_k127_1578920_2 PFAM Glycosyl transferase, family 20 K00697,K16055 - 2.4.1.15,2.4.1.347,3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004426 581.0
CMS2_k127_1578920_3 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 512.0
CMS2_k127_1578920_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 474.0
CMS2_k127_1578920_5 4Fe-4S dicluster domain K00124,K07307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005177 390.0
CMS2_k127_1578920_6 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 387.0
CMS2_k127_1578920_7 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 371.0
CMS2_k127_1578920_8 formate dehydrogenase K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 295.0
CMS2_k127_1578920_9 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000004433 257.0
CMS2_k127_158601_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 9.219e-258 817.0
CMS2_k127_158601_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 5.751e-220 691.0
CMS2_k127_158601_10 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 506.0
CMS2_k127_158601_11 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 484.0
CMS2_k127_158601_12 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 416.0
CMS2_k127_158601_13 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 392.0
CMS2_k127_158601_14 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009629 338.0
CMS2_k127_158601_15 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 326.0
CMS2_k127_158601_16 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001474 276.0
CMS2_k127_158601_17 TIGRFAM methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008238 258.0
CMS2_k127_158601_18 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000001534 235.0
CMS2_k127_158601_19 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.0000000000000000000000000000000000000000005218 167.0
CMS2_k127_158601_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 7.263e-215 685.0
CMS2_k127_158601_20 Rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000003459 160.0
CMS2_k127_158601_21 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.00000000000000000000000000000000000006997 145.0
CMS2_k127_158601_22 COG3245 Cytochrome c5 - - - 0.0000000000000000000000000000001615 129.0
CMS2_k127_158601_23 Phosphotransferase System K11189 - - 0.000000000000000000000000000001022 123.0
CMS2_k127_158601_24 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.000000000000000000000000000008318 128.0
CMS2_k127_158601_25 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000001969 115.0
CMS2_k127_158601_26 - - - - 0.000000000000000008888 93.0
CMS2_k127_158601_27 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000008522 92.0
CMS2_k127_158601_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 3.971e-212 675.0
CMS2_k127_158601_4 Rod shape-determining protein MreB K03569 - - 2.25e-202 632.0
CMS2_k127_158601_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.002e-194 618.0
CMS2_k127_158601_6 Major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 597.0
CMS2_k127_158601_7 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005526 581.0
CMS2_k127_158601_8 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 573.0
CMS2_k127_158601_9 transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 520.0
CMS2_k127_158978_0 pteridine-dependent deoxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 526.0
CMS2_k127_158978_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 465.0
CMS2_k127_158978_2 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 457.0
CMS2_k127_158978_3 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 426.0
CMS2_k127_158978_4 Phosphate acyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 413.0
CMS2_k127_158978_5 fad dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000002064 209.0
CMS2_k127_1609596_0 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 1.485e-225 716.0
CMS2_k127_1609596_1 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 336.0
CMS2_k127_1609596_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 304.0
CMS2_k127_1609596_3 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007817 286.0
CMS2_k127_1636577_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K11747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 575.0
CMS2_k127_1636577_1 pdz dhr glgf - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 452.0
CMS2_k127_1636577_2 Glutaredoxin-family domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 412.0
CMS2_k127_1636577_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 347.0
CMS2_k127_1636577_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 298.0
CMS2_k127_1636577_5 Flavin reductase like domain - - - 0.000000000000000000000000000000000001629 145.0
CMS2_k127_1636577_6 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000004556 85.0
CMS2_k127_1650238_0 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 1.032e-194 618.0
CMS2_k127_1650238_1 Transporter - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 571.0
CMS2_k127_1650238_10 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 346.0
CMS2_k127_1650238_11 ROK family K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004487 310.0
CMS2_k127_1650238_12 Phospholipase A1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001195 272.0
CMS2_k127_1650238_13 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001324 280.0
CMS2_k127_1650238_14 dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008679 267.0
CMS2_k127_1650238_15 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000001189 253.0
CMS2_k127_1650238_16 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000003235 250.0
CMS2_k127_1650238_17 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - - 0.0000000000000000000000000000000000000000000000000000000004724 216.0
CMS2_k127_1650238_18 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000395 216.0
CMS2_k127_1650238_19 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000001415 224.0
CMS2_k127_1650238_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 493.0
CMS2_k127_1650238_20 - - - - 0.0000000000000000000000000000000000000000000000000000003744 202.0
CMS2_k127_1650238_21 Protein of unknown function (DUF3237) - - - 0.00000000000000000000000000000000000000001115 171.0
CMS2_k127_1650238_22 Transposase IS200 like K07491 - - 0.0000000000000000000000000000004141 128.0
CMS2_k127_1650238_23 Domain of unknown function (DUF427) K01768 - 4.6.1.1 0.00000000000000000000000000001762 121.0
CMS2_k127_1650238_24 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000002379 108.0
CMS2_k127_1650238_25 Acetyltransferase (GNAT) domain - - - 0.000000000000000001034 89.0
CMS2_k127_1650238_26 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000005641 86.0
CMS2_k127_1650238_28 - - - - 0.0000001355 62.0
CMS2_k127_1650238_29 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs - - - 0.00002435 51.0
CMS2_k127_1650238_3 III protein, CoA-transferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 501.0
CMS2_k127_1650238_4 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 409.0
CMS2_k127_1650238_5 MltA-interacting protein MipA K07274 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 407.0
CMS2_k127_1650238_6 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 390.0
CMS2_k127_1650238_7 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 396.0
CMS2_k127_1650238_8 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 376.0
CMS2_k127_1650238_9 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 375.0
CMS2_k127_1711859_0 FAD dependent oxidoreductase K06954 - - 2.628e-218 693.0
CMS2_k127_1711859_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 564.0
CMS2_k127_1711859_2 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 363.0
CMS2_k127_1711859_3 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 298.0
CMS2_k127_1711859_4 Lipocalin-like domain K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005222 265.0
CMS2_k127_1711859_5 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000001537 244.0
CMS2_k127_1711859_6 Protein of unknown function (DUF2878) - - - 0.00000000000000000000000000000000000000009378 169.0
CMS2_k127_1714241_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 1.952e-207 660.0
CMS2_k127_1714241_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 529.0
CMS2_k127_1714241_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 464.0
CMS2_k127_1714241_3 RmlD substrate binding domain K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 309.0
CMS2_k127_1714241_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000001819 265.0
CMS2_k127_1714241_5 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000005995 124.0
CMS2_k127_1714241_6 Nucleotidyltransferase domain K07075 - - 0.000000000000000002184 91.0
CMS2_k127_1714241_7 Protein of unknown function DUF86 K07075 - - 0.0000000000000003626 84.0
CMS2_k127_1736497_0 D-aminoacylase domain protein K06015 - 3.5.1.81 4.548e-211 665.0
CMS2_k127_1736497_1 ATPase (AAA K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 400.0
CMS2_k127_1736497_2 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000002928 160.0
CMS2_k127_1736497_3 Protein of unknown function (DUF3301) - - - 0.000000000000000000000001654 106.0
CMS2_k127_1736497_4 Protein of unknown function DUF58 - - - 0.000000000000000000000003108 119.0
CMS2_k127_1736497_5 hydrolase activity - - - 0.0000000000000000001148 92.0
CMS2_k127_1740437_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 3.539e-212 670.0
CMS2_k127_1740437_1 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 529.0
CMS2_k127_1740437_2 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 530.0
CMS2_k127_1740437_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 349.0
CMS2_k127_1740437_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 327.0
CMS2_k127_1740437_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 329.0
CMS2_k127_1740437_6 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 300.0
CMS2_k127_1740437_7 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005959 261.0
CMS2_k127_1747984_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 1.483e-273 878.0
CMS2_k127_1747984_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 533.0
CMS2_k127_1747984_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 443.0
CMS2_k127_1747984_3 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000005214 251.0
CMS2_k127_1747984_4 PFAM regulatory protein, MerR - - - 0.00000000000000000000000000000000000000000000000008951 180.0
CMS2_k127_1747984_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000000001932 177.0
CMS2_k127_1747984_7 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides - - - 0.000005307 51.0
CMS2_k127_1753669_0 Cysteine-rich domain - - - 1.515e-225 706.0
CMS2_k127_1753669_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000002824 164.0
CMS2_k127_1753669_2 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000453 136.0
CMS2_k127_1876880_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 8.435e-199 639.0
CMS2_k127_1876880_1 FMN-dependent dehydrogenase K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 396.0
CMS2_k127_1876880_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000004381 283.0
CMS2_k127_1876880_3 cytochrome complex assembly - - - 0.0000000000000000000000000000000000000000001187 169.0
CMS2_k127_1876880_4 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000007858 139.0
CMS2_k127_1876880_6 cytochrome c biogenesis protein K07399 - - 0.000002636 53.0
CMS2_k127_1876880_7 PFAM NHL repeat containing protein - - - 0.000009482 57.0
CMS2_k127_1917635_0 SMART alpha amylase catalytic sub domain K00705,K06044 - 2.4.1.25,5.4.99.15 0.0 2022.0
CMS2_k127_1917635_1 SMART alpha amylase catalytic sub domain K05343 - 3.2.1.1,5.4.99.16 0.0 1536.0
CMS2_k127_1917635_2 PFAM glycoside hydrolase, family 13 domain protein K01214,K02438 - 3.2.1.196,3.2.1.68 0.0 1082.0
CMS2_k127_1917635_3 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 5.781e-299 934.0
CMS2_k127_1917635_4 SMART alpha amylase catalytic sub domain K01236 - 3.2.1.141 8.809e-252 819.0
CMS2_k127_1917635_5 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 559.0
CMS2_k127_1917635_6 Phosphofructokinase K00850,K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007734 404.0
CMS2_k127_1917635_7 PFAM Conserved TM helix repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002457 279.0
CMS2_k127_1926509_0 heat shock protein binding - - - 6.754e-225 711.0
CMS2_k127_1926509_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 602.0
CMS2_k127_1926509_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 525.0
CMS2_k127_1926509_3 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 397.0
CMS2_k127_1926509_4 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 367.0
CMS2_k127_1926509_5 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007444 272.0
CMS2_k127_1926509_6 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000007709 271.0
CMS2_k127_1926509_7 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001025 227.0
CMS2_k127_2033182_0 Magnesium chelatase, subunit ChlI K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 541.0
CMS2_k127_2033182_1 Membrane fusogenic activity K09806 - - 0.000000000000001341 83.0
CMS2_k127_2047379_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.571e-318 990.0
CMS2_k127_2047379_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.352e-226 723.0
CMS2_k127_2047379_10 Enoyl-CoA hydratase/isomerase K16427 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016701,GO:0016702,GO:0042802,GO:0051213,GO:0055114 1.13.11.80 0.000000000000003027 81.0
CMS2_k127_2047379_12 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000005539 52.0
CMS2_k127_2047379_2 Exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 560.0
CMS2_k127_2047379_3 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 383.0
CMS2_k127_2047379_4 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004337 277.0
CMS2_k127_2047379_5 Flavin-nucleotide-binding protein K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000001609 239.0
CMS2_k127_2047379_6 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000184 218.0
CMS2_k127_2047379_7 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000000000000003603 170.0
CMS2_k127_2047379_8 COG0655 Multimeric flavodoxin WrbA - - - 0.00000000000000000000000000000000000005513 153.0
CMS2_k127_2047379_9 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000000001908 145.0
CMS2_k127_205707_0 Divalent cation transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 446.0
CMS2_k127_205707_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 374.0
CMS2_k127_205707_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 314.0
CMS2_k127_205707_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 298.0
CMS2_k127_205707_4 - - - - 0.0000000000000000000000000000000000000000000000000000000533 214.0
CMS2_k127_205707_5 DoxX K15977 - - 0.000000000000000000000000000000000000000000001642 169.0
CMS2_k127_205707_6 Amidohydrolase K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000004428 165.0
CMS2_k127_205707_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000001289 136.0
CMS2_k127_205707_8 - - - - 0.0000000000000000000000446 103.0
CMS2_k127_205707_9 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000007564 99.0
CMS2_k127_2061067_0 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 521.0
CMS2_k127_2061067_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 436.0
CMS2_k127_2061067_2 Iron-containing alcohol dehydrogenase K13954,K19954 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 385.0
CMS2_k127_2061067_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 327.0
CMS2_k127_2061067_4 Sir2 family K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 309.0
CMS2_k127_2061067_5 PFAM aldo keto reductase K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000001705 245.0
CMS2_k127_2061067_6 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001688 213.0
CMS2_k127_2061067_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000243 182.0
CMS2_k127_2061067_8 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000003009 108.0
CMS2_k127_2061067_9 - - - - 0.00000000000008907 82.0
CMS2_k127_2062722_0 Domain of unknown function (DUF4872) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 485.0
CMS2_k127_2062722_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 314.0
CMS2_k127_2062722_2 - - - - 0.0000000000000000000000000000000000000205 145.0
CMS2_k127_2079165_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 9.713e-307 959.0
CMS2_k127_2079165_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 1.68e-208 666.0
CMS2_k127_2079165_10 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 333.0
CMS2_k127_2079165_11 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005654 300.0
CMS2_k127_2079165_12 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000002582 275.0
CMS2_k127_2079165_13 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000007209 250.0
CMS2_k127_2079165_14 Transcriptional regulator crp fnr family K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000177 251.0
CMS2_k127_2079165_15 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000001151 218.0
CMS2_k127_2079165_16 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.000000000000000000000000000000000000000000000000000000001125 218.0
CMS2_k127_2079165_17 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000002157 200.0
CMS2_k127_2079165_18 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000001509 199.0
CMS2_k127_2079165_19 periplasmic or secreted lipoprotein - - - 0.000000000000000000000000000000000000000000000006653 186.0
CMS2_k127_2079165_2 DNA replication, recombination, and repair K07478 - - 3.05e-198 627.0
CMS2_k127_2079165_20 Smr domain - - - 0.000000000000000000000000000000000000000000004254 183.0
CMS2_k127_2079165_21 - - - - 0.0000000000000000000005784 103.0
CMS2_k127_2079165_22 - - - - 0.00000000001793 67.0
CMS2_k127_2079165_23 FR47-like protein - - - 0.0000001071 64.0
CMS2_k127_2079165_24 HWE histidine kinase - - - 0.0000002722 58.0
CMS2_k127_2079165_25 receptor - - - 0.00005667 50.0
CMS2_k127_2079165_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 568.0
CMS2_k127_2079165_4 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 575.0
CMS2_k127_2079165_5 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 523.0
CMS2_k127_2079165_6 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 512.0
CMS2_k127_2079165_7 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 495.0
CMS2_k127_2079165_8 DEAD DEAH box helicase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 499.0
CMS2_k127_2079165_9 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 424.0
CMS2_k127_2084084_0 COG0577 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0 1053.0
CMS2_k127_2084084_1 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 561.0
CMS2_k127_2084084_2 COG1136 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 331.0
CMS2_k127_2084084_3 Pseudouridine synthase K06175 - 5.4.99.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 327.0
CMS2_k127_2084084_4 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000002914 102.0
CMS2_k127_2084084_5 - - - - 0.000002667 54.0
CMS2_k127_2106550_0 Acyl-CoA synthetase (NDP forming) K09181 - - 1.476e-258 818.0
CMS2_k127_2106550_1 UPF0365 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 496.0
CMS2_k127_2106550_2 serine protease K07403 - - 0.0000000000000001049 82.0
CMS2_k127_2106550_3 Bacterial protein of unknown function (DUF883) - - - 0.000000003831 70.0
CMS2_k127_2106550_4 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000008146 58.0
CMS2_k127_2122425_0 Biological Process cation transport (GO 0006812), Molecular Function solute hydrogen antiporter activity (GO 0015299), Cellular Component integral to membrane (GO 0016021), Biological Process transmembrane transport (GO 0055085) K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 407.0
CMS2_k127_2122425_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000001338 206.0
CMS2_k127_2124435_0 COG0765 ABC-type amino acid transport system, permease component K09971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 479.0
CMS2_k127_2124435_1 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 392.0
CMS2_k127_2124435_2 acid transport K09972 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 394.0
CMS2_k127_2124435_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000005481 191.0
CMS2_k127_2124435_4 acid transport system permease K09970 - - 0.00000000000000000000000000000000000004791 143.0
CMS2_k127_2138469_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 6.149e-268 837.0
CMS2_k127_2138469_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 358.0
CMS2_k127_2138469_2 HAD-superfamily hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000002835 244.0
CMS2_k127_2138469_3 rieske 2fe-2s - - - 0.000000000000000000000000000000000008137 142.0
CMS2_k127_2161942_0 AMP-binding enzyme K01895 - 6.2.1.1 2.027e-242 762.0
CMS2_k127_2161942_1 Tripartite tricarboxylate transporter TctA family K07793 - - 9.926e-223 700.0
CMS2_k127_2161942_10 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 310.0
CMS2_k127_2161942_11 alanine dehydrogenase K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003445 285.0
CMS2_k127_2161942_12 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005772 265.0
CMS2_k127_2161942_13 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000004239 268.0
CMS2_k127_2161942_14 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000512 203.0
CMS2_k127_2161942_15 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000006002 181.0
CMS2_k127_2161942_16 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000003791 154.0
CMS2_k127_2161942_17 Cytochrome c - - - 0.000000000000000000000000000000006041 131.0
CMS2_k127_2161942_19 Domain of unknown function (DUF4864) - - - 0.00000000000000000000000001871 115.0
CMS2_k127_2161942_2 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 586.0
CMS2_k127_2161942_20 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000002795 120.0
CMS2_k127_2161942_21 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000003927 108.0
CMS2_k127_2161942_22 Tetratricopeptide repeat - - - 0.00001677 58.0
CMS2_k127_2161942_3 PFAM Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 556.0
CMS2_k127_2161942_4 ATPase associated with various cellular activities, AAA_5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 514.0
CMS2_k127_2161942_5 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008412 520.0
CMS2_k127_2161942_6 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 403.0
CMS2_k127_2161942_7 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 404.0
CMS2_k127_2161942_8 Glycosyl transferase family 2 K11936,K14666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 375.0
CMS2_k127_2161942_9 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 351.0
CMS2_k127_2170240_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 581.0
CMS2_k127_2170240_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 338.0
CMS2_k127_2170240_2 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000000004067 123.0
CMS2_k127_2170240_3 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000006734 115.0
CMS2_k127_2176190_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1178.0
CMS2_k127_2176190_1 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 352.0
CMS2_k127_2176190_2 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004136 237.0
CMS2_k127_2176190_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000000000006465 204.0
CMS2_k127_2176190_4 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000001899 75.0
CMS2_k127_2182814_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 5.08e-215 684.0
CMS2_k127_2182814_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.621e-198 625.0
CMS2_k127_2182814_10 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002177 278.0
CMS2_k127_2182814_11 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001622 270.0
CMS2_k127_2182814_12 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007113 261.0
CMS2_k127_2182814_13 DNA replication, recombination and repair K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000005756 254.0
CMS2_k127_2182814_14 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000001152 244.0
CMS2_k127_2182814_15 Type IV pilus biogenesis stability protein PilW K02656 - - 0.0000000000000000000000000000000000000000000000000000000003077 222.0
CMS2_k127_2182814_16 PFAM GGDEF domain containing protein K21019 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000003513 216.0
CMS2_k127_2182814_17 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000000000005939 132.0
CMS2_k127_2182814_18 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000001209 90.0
CMS2_k127_2182814_19 Tetratricopeptide repeat-like domain - - - 0.0000000000000005143 84.0
CMS2_k127_2182814_2 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 522.0
CMS2_k127_2182814_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 514.0
CMS2_k127_2182814_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 501.0
CMS2_k127_2182814_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 392.0
CMS2_k127_2182814_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 334.0
CMS2_k127_2182814_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 295.0
CMS2_k127_2182814_8 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 297.0
CMS2_k127_2182814_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002196 290.0
CMS2_k127_2189052_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 6.041e-293 912.0
CMS2_k127_2189052_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.265e-281 872.0
CMS2_k127_2189052_10 Thioesterase superfamily K07107 - - 0.00000000000000000000000000000000006065 144.0
CMS2_k127_2189052_11 Electron transfer flavoprotein K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.00000000000000000000000000000001206 126.0
CMS2_k127_2189052_12 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.000000000000000000000000000001794 123.0
CMS2_k127_2189052_14 Phytanoyl-CoA dioxygenase (PhyH) K10674 - 1.14.11.55 0.0001036 50.0
CMS2_k127_2189052_2 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.239e-275 854.0
CMS2_k127_2189052_3 Acyl-CoA dehydrogenase N terminal K20035 - - 4.883e-245 769.0
CMS2_k127_2189052_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 5.062e-214 670.0
CMS2_k127_2189052_5 SAF - - - 2.265e-202 638.0
CMS2_k127_2189052_6 DAHP synthetase I family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 451.0
CMS2_k127_2189052_7 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 434.0
CMS2_k127_2189052_8 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004101 279.0
CMS2_k127_2189052_9 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001087 289.0
CMS2_k127_2208539_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 3.984e-256 794.0
CMS2_k127_2208539_1 formate hydrogenlyase subunit 3 multisubunit Na H antiporter, MnhD subunit K05568,K12137 - - 9.29e-241 756.0
CMS2_k127_2208539_10 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003217 251.0
CMS2_k127_2208539_11 Na H antiporter, MnhB K05566 - - 0.0000000000000000000000000000000000000000000000000000000000003042 223.0
CMS2_k127_2208539_12 Na H antiporter, MnhB K05566 - - 0.00000000000000000000000000000000000000000000000000000001133 209.0
CMS2_k127_2208539_13 COG1863 Multisubunit Na H antiporter MnhE subunit K05569 - - 0.00000000000000000000000000000000000000000000000006852 185.0
CMS2_k127_2208539_14 COG1006 Multisubunit Na H antiporter, MnhC subunit K05567 - - 0.000000000000000000000000000000000000000000002265 166.0
CMS2_k127_2208539_15 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.0000000000000000000000000004247 126.0
CMS2_k127_2208539_16 monovalent cation:proton antiporter activity K05571 - - 0.0000000000000000000000000125 118.0
CMS2_k127_2208539_17 - - - - 0.0000000000000000000000003325 110.0
CMS2_k127_2208539_18 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000173 102.0
CMS2_k127_2208539_2 Proton-conducting membrane transporter - - - 2.653e-215 681.0
CMS2_k127_2208539_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 7.647e-215 672.0
CMS2_k127_2208539_4 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 604.0
CMS2_k127_2208539_5 Proton-conducting membrane transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 583.0
CMS2_k127_2208539_6 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 466.0
CMS2_k127_2208539_7 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008608 422.0
CMS2_k127_2208539_8 peptidase C26 K01658,K07010 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 364.0
CMS2_k127_2208539_9 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004205 325.0
CMS2_k127_2214428_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1112.0
CMS2_k127_2214428_1 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 2.197e-288 899.0
CMS2_k127_2214428_10 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 291.0
CMS2_k127_2214428_11 Competence-damaged protein - - - 0.000000000000000000000000000000000000000000000000007121 185.0
CMS2_k127_2214428_12 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000002354 168.0
CMS2_k127_2214428_13 - - - - 0.0000000000000000000000000000000000000003652 155.0
CMS2_k127_2214428_14 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000009697 161.0
CMS2_k127_2214428_15 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000008123 132.0
CMS2_k127_2214428_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 611.0
CMS2_k127_2214428_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 466.0
CMS2_k127_2214428_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 443.0
CMS2_k127_2214428_5 protein conserved in bacteria K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 422.0
CMS2_k127_2214428_6 surface antigen (D15) K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 390.0
CMS2_k127_2214428_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 329.0
CMS2_k127_2214428_8 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 327.0
CMS2_k127_2214428_9 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 320.0
CMS2_k127_2259906_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 610.0
CMS2_k127_2259906_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 508.0
CMS2_k127_2259906_2 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 326.0
CMS2_k127_2259906_3 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000001544 219.0
CMS2_k127_2259906_4 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000002328 169.0
CMS2_k127_2259906_5 metal-dependent phosphohydrolase HD region K07814 - - 0.00000000000000001153 88.0
CMS2_k127_2259906_6 FecR protein - - - 0.00008467 50.0
CMS2_k127_2288511_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1276.0
CMS2_k127_2288511_1 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 3.512e-276 861.0
CMS2_k127_2288511_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 450.0
CMS2_k127_2288511_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 454.0
CMS2_k127_2288511_12 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 470.0
CMS2_k127_2288511_13 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 436.0
CMS2_k127_2288511_14 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 426.0
CMS2_k127_2288511_15 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01032 - 2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 412.0
CMS2_k127_2288511_16 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 433.0
CMS2_k127_2288511_17 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 366.0
CMS2_k127_2288511_18 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 365.0
CMS2_k127_2288511_19 cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 357.0
CMS2_k127_2288511_2 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 4.621e-215 686.0
CMS2_k127_2288511_20 Peptidase family M23 K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 333.0
CMS2_k127_2288511_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 334.0
CMS2_k127_2288511_22 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 317.0
CMS2_k127_2288511_23 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 306.0
CMS2_k127_2288511_24 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003783 286.0
CMS2_k127_2288511_25 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K22229 - 1.1.1.215 0.000000000000000000000000000000000000000000000000000000000008219 217.0
CMS2_k127_2288511_26 Protein of unknown function (DUF2953) - - - 0.000000000000000000000000000000000000000000000000000000006093 204.0
CMS2_k127_2288511_27 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.00000000000000000000000000000000000000000000008529 172.0
CMS2_k127_2288511_28 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000000000000000002764 175.0
CMS2_k127_2288511_29 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000001525 161.0
CMS2_k127_2288511_3 Metallopeptidase family M24 - - - 4.406e-210 661.0
CMS2_k127_2288511_30 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000002387 142.0
CMS2_k127_2288511_31 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000000000001377 111.0
CMS2_k127_2288511_33 Protein of unknown function (DUF721) - - - 0.00000001003 67.0
CMS2_k127_2288511_34 Dehydratase family K22186 - 4.2.1.82 0.000006658 50.0
CMS2_k127_2288511_35 - - - - 0.00001795 48.0
CMS2_k127_2288511_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 5.381e-208 674.0
CMS2_k127_2288511_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 3.749e-196 617.0
CMS2_k127_2288511_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 582.0
CMS2_k127_2288511_7 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009147 505.0
CMS2_k127_2288511_8 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 493.0
CMS2_k127_2288511_9 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 468.0
CMS2_k127_2305116_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.694e-260 809.0
CMS2_k127_2305116_1 CHASE2 K01768 - 4.6.1.1 5.242e-207 676.0
CMS2_k127_2305116_10 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 333.0
CMS2_k127_2305116_11 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 293.0
CMS2_k127_2305116_12 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004776 292.0
CMS2_k127_2305116_13 COG2513 PEP phosphonomutase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005656 264.0
CMS2_k127_2305116_14 quinone binding K12057,K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000004399 262.0
CMS2_k127_2305116_15 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000005224 273.0
CMS2_k127_2305116_16 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000816 224.0
CMS2_k127_2305116_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000009288 209.0
CMS2_k127_2305116_18 Thioredoxin K05838 - - 0.000000000000000000000000000000000000000000000000000000004566 209.0
CMS2_k127_2305116_19 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000113 171.0
CMS2_k127_2305116_2 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 557.0
CMS2_k127_2305116_20 - - - - 0.000000000000000000000000000000000000000001818 164.0
CMS2_k127_2305116_21 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000003653 150.0
CMS2_k127_2305116_22 PFAM Membrane protein of K08972 - - 0.00000000000000000000000000000004016 129.0
CMS2_k127_2305116_23 Protein of unknown function DUF86 - - - 0.0000000000000000000000000004659 116.0
CMS2_k127_2305116_24 Endoribonuclease L-PSP - - - 0.000000000000000000000000008084 111.0
CMS2_k127_2305116_25 transcriptional - - - 0.00000000000000001573 90.0
CMS2_k127_2305116_26 Sh3 type 3 domain protein - - - 0.0000000000001466 79.0
CMS2_k127_2305116_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 512.0
CMS2_k127_2305116_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 467.0
CMS2_k127_2305116_5 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 479.0
CMS2_k127_2305116_6 Biological Process cation transport (GO 0006812), Molecular Function solute hydrogen antiporter activity (GO 0015299), Cellular Component integral to membrane (GO 0016021), Biological Process transmembrane transport (GO 0055085) K03316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008202 455.0
CMS2_k127_2305116_7 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 443.0
CMS2_k127_2305116_8 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 423.0
CMS2_k127_2305116_9 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 328.0
CMS2_k127_23479_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 7.656e-221 700.0
CMS2_k127_23479_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 513.0
CMS2_k127_23479_2 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 386.0
CMS2_k127_23479_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 376.0
CMS2_k127_23479_4 NnrU protein - - - 0.00000000000000000000000000000000000000000000001476 179.0
CMS2_k127_23479_5 Thioesterase - - - 0.00000000000000000000000000000000000000003262 155.0
CMS2_k127_23479_6 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000002602 144.0
CMS2_k127_23479_7 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000009891 98.0
CMS2_k127_23479_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000007764 87.0
CMS2_k127_23575_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 2.537e-245 771.0
CMS2_k127_23575_1 FAD dependent oxidoreductase K00244 - 1.3.5.4 2.556e-227 722.0
CMS2_k127_23575_10 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001818 273.0
CMS2_k127_23575_11 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002538 242.0
CMS2_k127_23575_12 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000004006 240.0
CMS2_k127_23575_13 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000002669 203.0
CMS2_k127_23575_14 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000000000008313 190.0
CMS2_k127_23575_15 Protein of unknown function (DUF3237) - - - 0.000000000000000000000000000001266 136.0
CMS2_k127_23575_16 GYD domain - - - 0.00000000000000000000000000005805 121.0
CMS2_k127_23575_17 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000000000000001647 116.0
CMS2_k127_23575_19 Glyoxalase-like domain - - - 0.0000000000000002646 80.0
CMS2_k127_23575_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 1.484e-219 704.0
CMS2_k127_23575_20 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0004212 52.0
CMS2_k127_23575_3 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 488.0
CMS2_k127_23575_4 Methyl-transferase K06983 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 394.0
CMS2_k127_23575_5 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 344.0
CMS2_k127_23575_6 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 307.0
CMS2_k127_23575_7 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 306.0
CMS2_k127_23575_8 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000314 285.0
CMS2_k127_23575_9 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001135 256.0
CMS2_k127_2408601_0 Fumarate reductase flavoprotein C-term - - - 1.973e-216 700.0
CMS2_k127_2408601_1 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 431.0
CMS2_k127_2408601_2 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000007303 226.0
CMS2_k127_2408601_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000002508 164.0
CMS2_k127_2408601_4 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000002157 124.0
CMS2_k127_2413573_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 411.0
CMS2_k127_2413573_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 362.0
CMS2_k127_2413573_2 Belongs to the GST superfamily K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 325.0
CMS2_k127_2413573_3 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 324.0
CMS2_k127_2413573_4 - - - - 0.0000000000000000000000000000000000000000000000000000000005723 215.0
CMS2_k127_2413573_5 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000005358 170.0
CMS2_k127_2413573_6 transcriptional regulator - - - 0.0000000000000000000000002898 119.0
CMS2_k127_2413573_7 Protein of unknown function (DUF2905) - - - 0.000000000000000002567 87.0
CMS2_k127_2413573_8 Glutathione S-transferase K00799 - 2.5.1.18 0.0002294 44.0
CMS2_k127_2517727_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 5.99e-256 794.0
CMS2_k127_2517727_1 acyl-coa dehydrogenase - - - 6.717e-206 647.0
CMS2_k127_2517727_2 Enoyl-CoA hydratase/isomerase K13766,K13779 - 4.2.1.18,4.2.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 359.0
CMS2_k127_2517727_3 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001181 243.0
CMS2_k127_2517727_4 Gram-negative porin - - - 0.0000000000000000000001528 106.0
CMS2_k127_2522293_0 MMPL family - - - 0.0 1268.0
CMS2_k127_2522293_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1205.0
CMS2_k127_2522293_10 KR domain K07535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 335.0
CMS2_k127_2522293_11 4Fe-4S binding domain K18362 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 331.0
CMS2_k127_2522293_12 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 306.0
CMS2_k127_2522293_13 branched-chain amino acid transport K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 313.0
CMS2_k127_2522293_14 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005084 278.0
CMS2_k127_2522293_15 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001526 268.0
CMS2_k127_2522293_16 Belongs to the heme-copper respiratory oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002136 243.0
CMS2_k127_2522293_17 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000001706 223.0
CMS2_k127_2522293_18 Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000002027 172.0
CMS2_k127_2522293_19 Thioesterase - - - 0.000000000000000000000000000000000000000004646 158.0
CMS2_k127_2522293_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 603.0
CMS2_k127_2522293_20 DMSO reductase anchor subunit (DmsC) K18363 - - 0.0000000000000000000000000000000000000002374 166.0
CMS2_k127_2522293_21 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000001866 143.0
CMS2_k127_2522293_22 Thioesterase - - - 0.000000000000000000000000000000004676 135.0
CMS2_k127_2522293_23 transcriptional regulator - - - 0.00000000000000000000000000000006931 136.0
CMS2_k127_2522293_24 Invasion gene expression up-regulator SirB - - - 0.00000000000000000000000000002314 121.0
CMS2_k127_2522293_25 Hemerythrin HHE cation binding domain - - - 0.000000000000000004025 89.0
CMS2_k127_2522293_26 Universal stress protein family - - - 0.0000000000000005183 92.0
CMS2_k127_2522293_27 Heavy-metal-associated domain - - - 0.000000000003206 76.0
CMS2_k127_2522293_28 PFAM chemotaxis K03406,K07216 - - 0.00000000001124 78.0
CMS2_k127_2522293_29 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15268 - - 0.000000007366 66.0
CMS2_k127_2522293_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 587.0
CMS2_k127_2522293_4 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K04116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 542.0
CMS2_k127_2522293_5 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 522.0
CMS2_k127_2522293_6 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 471.0
CMS2_k127_2522293_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 362.0
CMS2_k127_2522293_8 PFAM NnrS family protein K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 364.0
CMS2_k127_2522293_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 370.0
CMS2_k127_252325_0 Peptidase family M1 domain - - - 7.093e-206 659.0
CMS2_k127_252325_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 507.0
CMS2_k127_252325_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 450.0
CMS2_k127_252325_3 Translation elongation factor K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 408.0
CMS2_k127_2538846_0 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 381.0
CMS2_k127_2538846_1 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000003892 249.0
CMS2_k127_2541361_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1058.0
CMS2_k127_2541361_1 Amidohydrolase family - - - 6.729e-225 708.0
CMS2_k127_2541361_10 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001283 291.0
CMS2_k127_2541361_11 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001665 262.0
CMS2_k127_2541361_12 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000002328 282.0
CMS2_k127_2541361_13 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000003726 255.0
CMS2_k127_2541361_14 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004512 256.0
CMS2_k127_2541361_15 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000002288 231.0
CMS2_k127_2541361_16 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000001114 229.0
CMS2_k127_2541361_17 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001039 213.0
CMS2_k127_2541361_18 Glutathione S-transferase, N-terminal domain K01800 - 5.2.1.2 0.000000000000000000000000000000000000000000000000000000003125 228.0
CMS2_k127_2541361_19 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000001719 183.0
CMS2_k127_2541361_2 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 543.0
CMS2_k127_2541361_20 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000001428 157.0
CMS2_k127_2541361_21 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000002268 163.0
CMS2_k127_2541361_22 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000001035 135.0
CMS2_k127_2541361_23 RelE toxin of RelE / RelB toxin-antitoxin system - - - 0.00000000000000000000000000001785 121.0
CMS2_k127_2541361_24 Helix-turn-helix XRE-family like proteins K07726 - - 0.0000000000000000000000000003887 118.0
CMS2_k127_2541361_3 Periplasmic binding protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 522.0
CMS2_k127_2541361_4 Isocitrate/isopropylmalate dehydrogenase K00031,K00052,K07246 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.42,1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 411.0
CMS2_k127_2541361_5 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 363.0
CMS2_k127_2541361_6 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 374.0
CMS2_k127_2541361_7 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 357.0
CMS2_k127_2541361_8 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04098 - 1.13.11.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 330.0
CMS2_k127_2541361_9 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002414 283.0
CMS2_k127_2543572_0 AcyL-CoA dehydrogenase K06445 - - 1.408e-316 990.0
CMS2_k127_2543572_1 ABC transporter transmembrane region K06147 - - 1.23e-238 751.0
CMS2_k127_2543572_10 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.0000000000000000000000000000000000000000006092 165.0
CMS2_k127_2543572_11 COG1607 Acyl-CoA hydrolase K10806 - - 0.00000000000000000000000001147 113.0
CMS2_k127_2543572_12 MarC family integral membrane protein K05595 - - 0.00001359 48.0
CMS2_k127_2543572_2 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 8.973e-225 734.0
CMS2_k127_2543572_3 Belongs to the thiolase family K00626 - 2.3.1.9 8.772e-204 645.0
CMS2_k127_2543572_4 L-lactate dehydrogenase K00101,K00104 - 1.1.2.3,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 547.0
CMS2_k127_2543572_5 Methyltransferase K18911 - 2.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 332.0
CMS2_k127_2543572_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 310.0
CMS2_k127_2543572_7 Belongs to the peptidase S11 family K07262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004529 266.0
CMS2_k127_2543572_8 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000006223 237.0
CMS2_k127_2543572_9 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000002562 240.0
CMS2_k127_2546739_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009946 464.0
CMS2_k127_2546739_1 major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 310.0
CMS2_k127_2546739_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000001151 261.0
CMS2_k127_2546739_3 Drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000003383 207.0
CMS2_k127_2548248_0 PFAM Fibronectin, type III domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 535.0
CMS2_k127_2548248_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 475.0
CMS2_k127_2548248_2 histidine kinase A domain protein K07679 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 322.0
CMS2_k127_2548248_3 PFAM response regulator receiver K15012 - - 0.000000000000000000000000000000000000000000000000000000000001896 216.0
CMS2_k127_2548248_4 histidine kinase A domain protein K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000001187 192.0
CMS2_k127_2548248_5 - - - - 0.0000000000000000000000000001222 132.0
CMS2_k127_2548248_6 6-phosphogluconolactonase activity - - - 0.000000000000000000000001344 111.0
CMS2_k127_2548248_7 Putative regulatory protein - - - 0.00000000000000002978 91.0
CMS2_k127_2576994_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.672e-276 871.0
CMS2_k127_2576994_1 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 7.381e-221 704.0
CMS2_k127_2576994_10 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000005278 187.0
CMS2_k127_2576994_2 ABC-type multidrug transport system, ATPase and permease K06147 - - 4.626e-196 631.0
CMS2_k127_2576994_3 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 587.0
CMS2_k127_2576994_4 glycolate oxidase iron-sulfur subunit K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 551.0
CMS2_k127_2576994_5 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 512.0
CMS2_k127_2576994_6 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 515.0
CMS2_k127_2576994_7 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 443.0
CMS2_k127_2576994_8 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 312.0
CMS2_k127_2576994_9 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000003402 251.0
CMS2_k127_2614135_0 PFAM DNA photolyase FAD-binding K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 588.0
CMS2_k127_2614135_1 Dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 557.0
CMS2_k127_2614135_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000009921 242.0
CMS2_k127_2614135_11 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000006727 220.0
CMS2_k127_2614135_12 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000008329 194.0
CMS2_k127_2614135_13 YHS domain protein - - - 0.00000000000000000000000000000000000000000000251 168.0
CMS2_k127_2614135_14 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000967 119.0
CMS2_k127_2614135_15 Belongs to the UPF0250 family K09158 - - 0.000000000000000000000000005002 124.0
CMS2_k127_2614135_2 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 504.0
CMS2_k127_2614135_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 480.0
CMS2_k127_2614135_4 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 475.0
CMS2_k127_2614135_5 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 432.0
CMS2_k127_2614135_6 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 404.0
CMS2_k127_2614135_7 Aminotransferase class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009185 382.0
CMS2_k127_2614135_8 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 370.0
CMS2_k127_2614135_9 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001974 277.0
CMS2_k127_2616602_0 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 3.202e-227 713.0
CMS2_k127_2616602_1 Domain of unknown function (DUF3459) K01236 - 3.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 509.0
CMS2_k127_264467_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.754e-315 975.0
CMS2_k127_264467_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 551.0
CMS2_k127_264467_2 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000001181 184.0
CMS2_k127_264467_3 OmpA family K03286 - - 0.00000000000000000000000000009708 123.0
CMS2_k127_2684499_0 TldD PmbA family protein K03568 - - 8.32e-225 704.0
CMS2_k127_2684499_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.992e-207 655.0
CMS2_k127_2684499_2 Protein of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 621.0
CMS2_k127_2684499_3 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 337.0
CMS2_k127_2684499_4 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 329.0
CMS2_k127_2684499_5 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000008433 280.0
CMS2_k127_2684499_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000005021 165.0
CMS2_k127_2708457_0 Uncharacterized ACR, YdiU/UPF0061 family - - - 5.555e-206 655.0
CMS2_k127_2708457_1 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 308.0
CMS2_k127_2708457_2 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003271 256.0
CMS2_k127_2708457_3 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000507 212.0
CMS2_k127_2708457_4 - - - - 0.00000000000000000000000000000000000000000000000009118 190.0
CMS2_k127_2708457_5 FecR protein - - - 0.000000000000000000000000000000000008598 147.0
CMS2_k127_2708457_6 FecR protein - - - 0.00000000000000000000000000006824 126.0
CMS2_k127_2708457_7 PFAM response regulator receiver K07657 - - 0.000000000000000204 89.0
CMS2_k127_2721998_0 Penicillin amidase K01434 - 3.5.1.11 5.253e-278 876.0
CMS2_k127_2721998_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.829e-245 773.0
CMS2_k127_2721998_10 - K07341 - - 0.00000000000000000000000000000000000000000008076 165.0
CMS2_k127_2721998_11 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000036 118.0
CMS2_k127_2721998_12 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000005615 126.0
CMS2_k127_2721998_13 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000001735 98.0
CMS2_k127_2721998_14 helix_turn_helix, Lux Regulon - GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000003524 96.0
CMS2_k127_2721998_16 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000001836 68.0
CMS2_k127_2721998_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 548.0
CMS2_k127_2721998_3 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 514.0
CMS2_k127_2721998_4 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715,K07534 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 376.0
CMS2_k127_2721998_5 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 329.0
CMS2_k127_2721998_6 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 318.0
CMS2_k127_2721998_7 Phenylacetic acid degradation protein PaaY K02617,K08279 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.0000000000000000000000000000000000000000000000000000000000000000000000007152 255.0
CMS2_k127_2721998_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008258 247.0
CMS2_k127_2721998_9 TIGRFAM Urea carboxylase-associated protein 1 K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000001852 228.0
CMS2_k127_2759174_0 AMP-binding enzyme K12508 - 6.2.1.34 1.436e-198 634.0
CMS2_k127_2759174_1 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 591.0
CMS2_k127_2759174_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000006517 254.0
CMS2_k127_2759174_11 catechol 1,2-dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000001963 208.0
CMS2_k127_2759174_12 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000003936 200.0
CMS2_k127_2759174_13 Protein of unknown function DUF126 K09128 - - 0.00000000000000000000000000000000000000351 164.0
CMS2_k127_2759174_14 thioesterase K01075 - 3.1.2.23 0.000000000000000000000000000000002035 133.0
CMS2_k127_2759174_15 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000926 63.0
CMS2_k127_2759174_2 FAD binding domain K00481 - 1.14.13.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 561.0
CMS2_k127_2759174_3 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 542.0
CMS2_k127_2759174_4 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 379.0
CMS2_k127_2759174_5 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 400.0
CMS2_k127_2759174_6 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 394.0
CMS2_k127_2759174_7 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 343.0
CMS2_k127_2759174_8 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 332.0
CMS2_k127_2759174_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 310.0
CMS2_k127_2770263_0 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 7.793e-199 629.0
CMS2_k127_2770263_1 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 349.0
CMS2_k127_2770263_2 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000001688 256.0
CMS2_k127_2770263_3 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000001389 175.0
CMS2_k127_2770263_4 SnoaL-like domain - - - 0.00000000001094 67.0
CMS2_k127_2819515_0 Methyl-transferase K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 412.0
CMS2_k127_2819515_1 Rhodanese Homology Domain K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 384.0
CMS2_k127_2819515_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 289.0
CMS2_k127_2819515_3 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000006895 81.0
CMS2_k127_2819515_4 LysR substrate binding domain - - - 0.0000000000001243 77.0
CMS2_k127_2823315_0 GXGXG motif K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2293.0
CMS2_k127_2823315_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 1.579e-290 912.0
CMS2_k127_2823315_10 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 475.0
CMS2_k127_2823315_11 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 424.0
CMS2_k127_2823315_12 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 390.0
CMS2_k127_2823315_13 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 301.0
CMS2_k127_2823315_14 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000014 277.0
CMS2_k127_2823315_15 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003194 265.0
CMS2_k127_2823315_16 Pilus assembly protein PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006563 254.0
CMS2_k127_2823315_17 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000001062 239.0
CMS2_k127_2823315_18 Shikimate kinase K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000003132 225.0
CMS2_k127_2823315_19 fimbrial biogenesis protein PilN K02663 - - 0.000000000000000000000000000000000000000000000000000000234 202.0
CMS2_k127_2823315_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 9.012e-278 864.0
CMS2_k127_2823315_20 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000001017 191.0
CMS2_k127_2823315_21 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000002672 185.0
CMS2_k127_2823315_22 pilus assembly protein PilP K02665 - - 0.000000000000000000000000000000000000000000004992 177.0
CMS2_k127_2823315_23 Inorganic ion transport and metabolism K06202 - - 0.0000000000000000000000000000001871 131.0
CMS2_k127_2823315_24 Domain of unknown function (DUF4396) - - - 0.00000000000000000000000000002164 118.0
CMS2_k127_2823315_25 PFAM cytochrome c - - - 0.0000000000000001236 86.0
CMS2_k127_2823315_26 - - - - 0.0000001939 60.0
CMS2_k127_2823315_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 5.494e-242 754.0
CMS2_k127_2823315_4 Secretin and TonB N terminus short domain K02666 - - 2.967e-237 753.0
CMS2_k127_2823315_5 multicopper oxidase type 3 K22348 - 1.16.3.3 2.651e-228 711.0
CMS2_k127_2823315_6 Oxidoreductase - - - 1.48e-211 668.0
CMS2_k127_2823315_7 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 527.0
CMS2_k127_2823315_8 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 502.0
CMS2_k127_2823315_9 Pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 475.0
CMS2_k127_2914515_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1380.0
CMS2_k127_2914515_1 Peptidase family M3 K01414 - 3.4.24.70 9.732e-304 944.0
CMS2_k127_2914515_10 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 310.0
CMS2_k127_2914515_11 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000000005428 173.0
CMS2_k127_2914515_12 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000138 124.0
CMS2_k127_2914515_13 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000005456 74.0
CMS2_k127_2914515_2 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzymes K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 7.711e-235 732.0
CMS2_k127_2914515_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 8.209e-202 641.0
CMS2_k127_2914515_4 TIGRFAM malate synthase A K01638 - 2.3.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 529.0
CMS2_k127_2914515_5 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 464.0
CMS2_k127_2914515_6 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 369.0
CMS2_k127_2914515_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 336.0
CMS2_k127_2914515_8 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 327.0
CMS2_k127_2914515_9 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 316.0
CMS2_k127_2925536_0 Bacterial extracellular solute-binding protein K10236 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 497.0
CMS2_k127_2925536_1 transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 364.0
CMS2_k127_2925536_2 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.0000000000000000000000000000008968 139.0
CMS2_k127_2946245_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 320.0
CMS2_k127_2946245_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 297.0
CMS2_k127_2946245_2 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000004052 226.0
CMS2_k127_2946245_3 FtsX-like permease family K02004 - - 0.00000000000000000000000000000006798 138.0
CMS2_k127_2984764_0 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain, Biotin carboxylase C-terminal domain, Carbamoyl-phosphate synthase L chain, N-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 1.283e-250 779.0
CMS2_k127_2984764_1 RNB K01147 - 3.1.13.1 5.413e-204 652.0
CMS2_k127_2984764_10 Methyl-accepting chemotaxis protein K02660 - - 0.00000000000000000000000000000000000000000000000000000961 207.0
CMS2_k127_2984764_11 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000002625 203.0
CMS2_k127_2984764_12 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000004359 185.0
CMS2_k127_2984764_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000004447 189.0
CMS2_k127_2984764_14 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000003337 183.0
CMS2_k127_2984764_15 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000002278 174.0
CMS2_k127_2984764_16 - - - - 0.000000000000000000000000000000000000000000001388 173.0
CMS2_k127_2984764_17 Protein of unknown function (DUF3426) - - - 0.000000000000000000000000000000000001457 150.0
CMS2_k127_2984764_18 Rubredoxin - - - 0.000000000000000000000000000000197 126.0
CMS2_k127_2984764_2 Mur ligase family, catalytic domain K02558 - 6.3.2.45 4.492e-197 624.0
CMS2_k127_2984764_3 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 602.0
CMS2_k127_2984764_4 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 435.0
CMS2_k127_2984764_5 Shikimate dehydrogenase substrate binding domain K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 295.0
CMS2_k127_2984764_6 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004563 286.0
CMS2_k127_2984764_7 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007038 276.0
CMS2_k127_2984764_8 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000001026 263.0
CMS2_k127_2984764_9 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000009864 239.0
CMS2_k127_298581_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 2.91e-208 654.0
CMS2_k127_298581_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 566.0
CMS2_k127_298581_2 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 527.0
CMS2_k127_298581_3 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001169 264.0
CMS2_k127_298581_4 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000001916 215.0
CMS2_k127_298581_5 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000002377 121.0
CMS2_k127_298581_6 COG0457 FOG TPR repeat - - - 0.000000000000000000000269 102.0
CMS2_k127_298581_7 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000003735 100.0
CMS2_k127_298581_8 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.0000005359 62.0
CMS2_k127_3000108_0 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 411.0
CMS2_k127_3000108_1 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 350.0
CMS2_k127_3000108_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000007752 120.0
CMS2_k127_3054061_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 530.0
CMS2_k127_3054061_1 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 421.0
CMS2_k127_3054061_2 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 362.0
CMS2_k127_3054061_3 KR domain K00076,K08081 - 1.1.1.159,1.1.1.206 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 321.0
CMS2_k127_3054061_4 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005775 313.0
CMS2_k127_3054061_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002301 250.0
CMS2_k127_3054061_6 PFAM RDD domain containing protein - - - 0.00000000000000000000000000000000000002476 161.0
CMS2_k127_3054061_7 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000006033 144.0
CMS2_k127_3074631_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1326.0
CMS2_k127_3074631_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000517 605.0
CMS2_k127_3074631_10 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000002451 188.0
CMS2_k127_3074631_11 PBP superfamily domain - - - 0.000000000000000000000000000000000000000000000002864 185.0
CMS2_k127_3074631_12 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000004757 141.0
CMS2_k127_3074631_13 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000001575 117.0
CMS2_k127_3074631_14 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000002129 111.0
CMS2_k127_3074631_15 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000008994 82.0
CMS2_k127_3074631_16 Chromate resistance exported protein - - - 0.000000002332 68.0
CMS2_k127_3074631_17 - - - - 0.00000001104 61.0
CMS2_k127_3074631_2 Molybdenum cofactor synthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 514.0
CMS2_k127_3074631_3 4Fe-4S ferredoxin, iron-sulfur binding K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 398.0
CMS2_k127_3074631_4 formate dehydrogenase K00127 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 379.0
CMS2_k127_3074631_5 Bacterial extracellular solute-binding protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 358.0
CMS2_k127_3074631_6 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 291.0
CMS2_k127_3074631_7 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 289.0
CMS2_k127_3074631_8 Sulfite exporter TauE/SafE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007589 244.0
CMS2_k127_3074631_9 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000001197 228.0
CMS2_k127_3102879_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K22015 - 1.17.1.9,1.17.99.7 0.0 1391.0
CMS2_k127_3102879_1 AMP-dependent synthetase - - - 3.257e-296 945.0
CMS2_k127_3102879_10 Cyclic nucleotide-monophosphate binding domain K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000115 63.0
CMS2_k127_3102879_12 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00004128 57.0
CMS2_k127_3102879_2 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 1.843e-292 905.0
CMS2_k127_3102879_3 24 kD subunit K00122 - 1.17.1.9 2.739e-269 837.0
CMS2_k127_3102879_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 434.0
CMS2_k127_3102879_5 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 426.0
CMS2_k127_3102879_6 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008527 368.0
CMS2_k127_3102879_7 glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 350.0
CMS2_k127_3102879_8 Membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 330.0
CMS2_k127_3102879_9 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000002778 163.0
CMS2_k127_313432_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 548.0
CMS2_k127_313432_1 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 402.0
CMS2_k127_313432_2 protein involved in response to NO K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 321.0
CMS2_k127_313432_3 III protein, CoA-transferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 307.0
CMS2_k127_313432_4 abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 320.0
CMS2_k127_313432_5 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 291.0
CMS2_k127_313432_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000002206 252.0
CMS2_k127_313432_7 V4R - - - 0.00000000000000000000000000002371 123.0
CMS2_k127_3166252_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 1.12e-290 920.0
CMS2_k127_3166252_1 Protein of unknown function (DUF1116) - - - 3.546e-196 623.0
CMS2_k127_3166252_2 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 482.0
CMS2_k127_3166252_3 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008331 381.0
CMS2_k127_3166252_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000002707 199.0
CMS2_k127_3166252_5 Protein of unknown function (DUF2877) - - - 0.00000000000000000000000000000000485 139.0
CMS2_k127_3166252_6 - - - - 0.00007786 55.0
CMS2_k127_3176324_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 599.0
CMS2_k127_3176324_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 467.0
CMS2_k127_3176324_2 PFAM Glutamine amidotransferase class-I K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001606 299.0
CMS2_k127_3176324_3 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000001082 267.0
CMS2_k127_3236454_0 elongation factor G K02355 - - 2.552e-287 900.0
CMS2_k127_3236454_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 4.541e-254 794.0
CMS2_k127_3236454_10 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 357.0
CMS2_k127_3236454_11 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 326.0
CMS2_k127_3236454_12 HlyD membrane-fusion protein of T1SS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 307.0
CMS2_k127_3236454_13 NAD-dependent epimerase dehydratase K18981 - 1.1.1.203 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 294.0
CMS2_k127_3236454_14 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001895 284.0
CMS2_k127_3236454_15 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003045 286.0
CMS2_k127_3236454_16 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000448 264.0
CMS2_k127_3236454_17 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000009882 229.0
CMS2_k127_3236454_18 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000526 181.0
CMS2_k127_3236454_19 sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000003464 169.0
CMS2_k127_3236454_2 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 1.579e-200 631.0
CMS2_k127_3236454_20 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000004229 168.0
CMS2_k127_3236454_21 - - - - 0.00000000000000000000000000000000000000003557 168.0
CMS2_k127_3236454_22 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000002125 145.0
CMS2_k127_3236454_23 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000003216 139.0
CMS2_k127_3236454_24 Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000003705 131.0
CMS2_k127_3236454_25 BON domain - - - 0.00000000000000000000000000005728 121.0
CMS2_k127_3236454_26 Domain of unknown function (DUF4124) - - - 0.000000000000000000001534 97.0
CMS2_k127_3236454_27 - - - - 0.000000000000002591 76.0
CMS2_k127_3236454_28 Domain of unknown function (DUF4340) - - - 0.000000001415 72.0
CMS2_k127_3236454_3 reductase, alpha subunit K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 594.0
CMS2_k127_3236454_4 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007714 585.0
CMS2_k127_3236454_5 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 470.0
CMS2_k127_3236454_6 PFAM SMP-30 Gluconolaconase LRE domain protein K01053,K14274 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 457.0
CMS2_k127_3236454_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 402.0
CMS2_k127_3236454_8 Belongs to the mandelate racemase muconate lactonizing enzyme family K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 374.0
CMS2_k127_3236454_9 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 356.0
CMS2_k127_3248919_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 1.895e-201 643.0
CMS2_k127_3248919_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 368.0
CMS2_k127_3248919_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002381 261.0
CMS2_k127_3248919_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000000000000000000001386 206.0
CMS2_k127_3248919_4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000186 195.0
CMS2_k127_3248919_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.0003295 51.0
CMS2_k127_3263421_0 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.0 1387.0
CMS2_k127_3263421_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 4.361e-268 828.0
CMS2_k127_3263421_10 DSBA-like thioredoxin domain K07396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000635 284.0
CMS2_k127_3263421_11 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287,K18590 - 1.5.1.3 0.000000000000000000000000000000000000000000000000000000000000002454 233.0
CMS2_k127_3263421_12 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000004523 228.0
CMS2_k127_3263421_13 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030,K10001 - - 0.000000000000000000000000000000000001191 142.0
CMS2_k127_3263421_14 Cytochrome oxidase maturation protein cbb3-type - - - 0.000000000000000000000003435 102.0
CMS2_k127_3263421_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005548 508.0
CMS2_k127_3263421_3 Arginine-tRNA-protein transferase, N terminus K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 471.0
CMS2_k127_3263421_4 FecCD transport family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 479.0
CMS2_k127_3263421_5 Leucyl/phenylalanyl-tRNA protein transferase K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 418.0
CMS2_k127_3263421_6 Belongs to the peptidase M48B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 433.0
CMS2_k127_3263421_7 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 413.0
CMS2_k127_3263421_8 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 392.0
CMS2_k127_3263421_9 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 351.0
CMS2_k127_3312999_0 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 417.0
CMS2_k127_3312999_1 Alpha beta hydrolase K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 403.0
CMS2_k127_3312999_10 Protein of unknown function (DUF560) - - - 0.00000000000000000000000000000002374 142.0
CMS2_k127_3312999_11 COGs COG4446 conserved - - - 0.0000000000000000000000000000007717 138.0
CMS2_k127_3312999_12 PFAM FecR protein K03832 - - 0.00000000000000000000002374 111.0
CMS2_k127_3312999_13 small protein containing a coiled-coil domain - - - 0.00000000009095 71.0
CMS2_k127_3312999_2 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 398.0
CMS2_k127_3312999_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007912 295.0
CMS2_k127_3312999_4 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001157 283.0
CMS2_k127_3312999_5 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009293 269.0
CMS2_k127_3312999_6 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001005 251.0
CMS2_k127_3312999_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000004974 212.0
CMS2_k127_3312999_8 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000002619 184.0
CMS2_k127_3312999_9 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000001434 139.0
CMS2_k127_3362114_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 6.329e-224 712.0
CMS2_k127_3362114_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 1.216e-211 667.0
CMS2_k127_3362114_10 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0002844 47.0
CMS2_k127_3362114_2 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 593.0
CMS2_k127_3362114_3 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 569.0
CMS2_k127_3362114_4 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 563.0
CMS2_k127_3362114_5 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 360.0
CMS2_k127_3362114_6 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 360.0
CMS2_k127_3362114_7 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000984 320.0
CMS2_k127_3362114_8 ferredoxin - - - 0.00000000000000000000000000000000001071 136.0
CMS2_k127_3362114_9 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000002462 69.0
CMS2_k127_3390728_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1707.0
CMS2_k127_3390728_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1469.0
CMS2_k127_3390728_10 Aldo Keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 444.0
CMS2_k127_3390728_11 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 411.0
CMS2_k127_3390728_12 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 385.0
CMS2_k127_3390728_13 Zinc-binding dehydrogenase K12957,K13953,K19961 - 1.1.1.1,1.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 384.0
CMS2_k127_3390728_14 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 352.0
CMS2_k127_3390728_15 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 333.0
CMS2_k127_3390728_16 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 332.0
CMS2_k127_3390728_17 Bacterial transglutaminase-like N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 319.0
CMS2_k127_3390728_18 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 327.0
CMS2_k127_3390728_19 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 306.0
CMS2_k127_3390728_2 Circularly permuted ATP-grasp type 2 - - - 1.024e-312 978.0
CMS2_k127_3390728_20 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 293.0
CMS2_k127_3390728_21 alpha/beta hydrolase fold K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 307.0
CMS2_k127_3390728_22 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 302.0
CMS2_k127_3390728_23 zinc protease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007626 293.0
CMS2_k127_3390728_24 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003423 280.0
CMS2_k127_3390728_25 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002745 276.0
CMS2_k127_3390728_26 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001261 281.0
CMS2_k127_3390728_27 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002918 278.0
CMS2_k127_3390728_28 Glutathione S-Transferase K00799 GO:0003674,GO:0003824,GO:0004364,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016740,GO:0016765,GO:0030611,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000007392 266.0
CMS2_k127_3390728_29 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000676 235.0
CMS2_k127_3390728_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 2.318e-251 807.0
CMS2_k127_3390728_30 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000006289 216.0
CMS2_k127_3390728_31 - - - - 0.000000000000000000000000000000000000000000000000000000000007797 216.0
CMS2_k127_3390728_32 transglutaminase - - - 0.00000000000000000000000000000000000000000000000000000000004207 214.0
CMS2_k127_3390728_33 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000007774 203.0
CMS2_k127_3390728_34 2-phosphosulfolactate phosphatase activity K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000000000000000000000000000000000000000000000001187 201.0
CMS2_k127_3390728_35 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.000000000000000000000000000000000000000000000002232 183.0
CMS2_k127_3390728_36 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000008204 177.0
CMS2_k127_3390728_37 NIPSNAP - - - 0.00000000000000000000000000000000000000000000006382 171.0
CMS2_k127_3390728_38 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.0000000000000000000000000000000000000001111 168.0
CMS2_k127_3390728_39 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000008643 156.0
CMS2_k127_3390728_4 Circularly permuted ATP-grasp type 2 - - - 3.253e-230 720.0
CMS2_k127_3390728_40 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000001251 163.0
CMS2_k127_3390728_41 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000005442 148.0
CMS2_k127_3390728_42 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000002768 153.0
CMS2_k127_3390728_43 dehydratase - - - 0.000000000000000000000000000000262 124.0
CMS2_k127_3390728_44 Guanyl-specific ribonuclease Sa - - - 0.00000000000000000000000000000118 130.0
CMS2_k127_3390728_46 Putative regulatory protein - - - 0.0000000000000000000000001747 112.0
CMS2_k127_3390728_47 FAD linked oxidase - - - 0.0000000000000000000002707 110.0
CMS2_k127_3390728_48 (barnase) inhibitor - - - 0.000000000000000001204 91.0
CMS2_k127_3390728_49 - - - - 0.000000003092 66.0
CMS2_k127_3390728_5 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 1.373e-222 704.0
CMS2_k127_3390728_6 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 4.255e-222 717.0
CMS2_k127_3390728_7 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 2.025e-218 724.0
CMS2_k127_3390728_8 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.593e-211 662.0
CMS2_k127_3390728_9 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 550.0
CMS2_k127_3399217_0 Fumarate reductase flavoprotein C-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 597.0
CMS2_k127_3399217_1 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000852 261.0
CMS2_k127_3406523_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 563.0
CMS2_k127_3406523_1 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 511.0
CMS2_k127_3406523_10 response regulator receiver K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000001223 234.0
CMS2_k127_3406523_11 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000008179 201.0
CMS2_k127_3406523_12 Rhodanese-like domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000004174 199.0
CMS2_k127_3406523_13 Haem-degrading - - - 0.00000000000000000000000000000000000000000001658 181.0
CMS2_k127_3406523_14 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000009072 166.0
CMS2_k127_3406523_15 DsrC like protein - - - 0.00000000000000000000000000000000000000001146 157.0
CMS2_k127_3406523_16 SAF K16845 - 4.4.1.24 0.0000000000000000000000000000461 117.0
CMS2_k127_3406523_17 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000005704 109.0
CMS2_k127_3406523_18 Rieske-like [2Fe-2S] domain - - - 0.00000000000000000000001106 107.0
CMS2_k127_3406523_19 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000001759 73.0
CMS2_k127_3406523_2 oxidoreductase FAD NAD(P)-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 476.0
CMS2_k127_3406523_3 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 463.0
CMS2_k127_3406523_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 444.0
CMS2_k127_3406523_5 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 439.0
CMS2_k127_3406523_6 PFAM Glycosyl transferase, family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 427.0
CMS2_k127_3406523_7 Belongs to the class I fructose-bisphosphate aldolase family K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 412.0
CMS2_k127_3406523_8 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 319.0
CMS2_k127_3406523_9 Histidine kinase K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 298.0
CMS2_k127_34252_0 ABC transporter - - - 4.15e-240 754.0
CMS2_k127_34252_1 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 2.349e-236 765.0
CMS2_k127_34252_10 PFAM Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003767 242.0
CMS2_k127_34252_11 membrane protein domain - - - 0.000000000000000000000000000000000000000000000000000000002112 208.0
CMS2_k127_34252_12 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000001232 194.0
CMS2_k127_34252_13 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000001075 188.0
CMS2_k127_34252_14 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.0000000000000000000000000000000000000000000000000002215 202.0
CMS2_k127_34252_15 - - - - 0.0000000000000000000000000000000000000000000009306 176.0
CMS2_k127_34252_16 - - - - 0.0000000000000000000000000000000004218 133.0
CMS2_k127_34252_17 addiction module killer protein - - - 0.0000000000000000000000000000004281 126.0
CMS2_k127_34252_18 Predicted metal-dependent hydrolase K07044 - - 0.000000000000000000000000008467 121.0
CMS2_k127_34252_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.066e-235 735.0
CMS2_k127_34252_3 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 2.071e-203 663.0
CMS2_k127_34252_4 COG1271 Cytochrome bd-type quinol oxidase, subunit 1 K00425 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 567.0
CMS2_k127_34252_5 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 421.0
CMS2_k127_34252_6 cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 375.0
CMS2_k127_34252_7 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 341.0
CMS2_k127_34252_8 Stage II sporulation protein M - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 312.0
CMS2_k127_34252_9 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 273.0
CMS2_k127_3425621_0 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 1.974e-208 672.0
CMS2_k127_3425621_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 414.0
CMS2_k127_3425621_2 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000006016 186.0
CMS2_k127_3425621_3 protein conserved in bacteria K11719 - - 0.00000000000000000000000000005868 129.0
CMS2_k127_3425621_4 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000003078 110.0
CMS2_k127_342633_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1135.0
CMS2_k127_342633_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1124.0
CMS2_k127_342633_10 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 579.0
CMS2_k127_342633_11 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 548.0
CMS2_k127_342633_12 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 475.0
CMS2_k127_342633_13 Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 447.0
CMS2_k127_342633_14 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 425.0
CMS2_k127_342633_15 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 418.0
CMS2_k127_342633_16 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 416.0
CMS2_k127_342633_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007084 411.0
CMS2_k127_342633_18 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 376.0
CMS2_k127_342633_19 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 357.0
CMS2_k127_342633_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.0 1069.0
CMS2_k127_342633_20 Permease, YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 382.0
CMS2_k127_342633_21 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 350.0
CMS2_k127_342633_22 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 350.0
CMS2_k127_342633_23 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 302.0
CMS2_k127_342633_24 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 299.0
CMS2_k127_342633_25 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004939 271.0
CMS2_k127_342633_26 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002245 261.0
CMS2_k127_342633_27 Acetolactate synthase small K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001189 253.0
CMS2_k127_342633_28 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003326 272.0
CMS2_k127_342633_29 Chromate resistance - - - 0.0000000000000000000000000000000000000000000000000000000000003602 223.0
CMS2_k127_342633_3 Belongs to the TPP enzyme family K01577 - 4.1.1.8 1.793e-321 990.0
CMS2_k127_342633_30 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000003617 195.0
CMS2_k127_342633_31 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000004577 204.0
CMS2_k127_342633_32 Tfp pilus assembly protein, major pilin PilA K02650 - - 0.0000000000000000000000000000000000000000000003671 172.0
CMS2_k127_342633_33 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000902 170.0
CMS2_k127_342633_34 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000001345 162.0
CMS2_k127_342633_35 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.0000000000000000000000000000000000000002534 166.0
CMS2_k127_342633_36 transcription elongation factor GreA GreB K06140 - - 0.000000000000000000000000000000000002035 143.0
CMS2_k127_342633_37 Protein of unknown function (DUF3106) - - - 0.000000000000000000000002674 108.0
CMS2_k127_342633_38 RDD family - - - 0.00000000000000000002841 103.0
CMS2_k127_342633_39 Protein of unknown function (DUF3619) - - - 0.0000000000000000401 86.0
CMS2_k127_342633_4 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 3.057e-303 946.0
CMS2_k127_342633_5 CHASE2 K01768 - 4.6.1.1 2.585e-278 874.0
CMS2_k127_342633_6 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.211e-247 775.0
CMS2_k127_342633_7 Tripartite tricarboxylate transporter TctA family K07793 - - 1.105e-241 756.0
CMS2_k127_342633_8 metal-dependent phosphohydrolase HD sub domain - - - 2.262e-233 734.0
CMS2_k127_342633_9 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 601.0
CMS2_k127_3440871_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0 1131.0
CMS2_k127_3440871_1 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 2.535e-306 946.0
CMS2_k127_3440871_10 Peptidase family U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 484.0
CMS2_k127_3440871_11 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 448.0
CMS2_k127_3440871_12 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 411.0
CMS2_k127_3440871_13 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 400.0
CMS2_k127_3440871_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 373.0
CMS2_k127_3440871_15 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 372.0
CMS2_k127_3440871_16 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 359.0
CMS2_k127_3440871_17 Peptidase U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 366.0
CMS2_k127_3440871_18 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 367.0
CMS2_k127_3440871_19 Divalent cation transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 316.0
CMS2_k127_3440871_2 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 1.221e-258 807.0
CMS2_k127_3440871_20 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008348 314.0
CMS2_k127_3440871_21 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 295.0
CMS2_k127_3440871_22 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000216 282.0
CMS2_k127_3440871_23 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003328 265.0
CMS2_k127_3440871_24 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000003005 252.0
CMS2_k127_3440871_25 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008678 266.0
CMS2_k127_3440871_26 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000116 233.0
CMS2_k127_3440871_27 Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000000000000000000000000000000000393 211.0
CMS2_k127_3440871_28 Hemerythrin HHE cation binding - - - 0.0000000000000000000000000000000000000000457 164.0
CMS2_k127_3440871_29 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000006716 163.0
CMS2_k127_3440871_3 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 2.034e-249 795.0
CMS2_k127_3440871_30 CoA-binding domain protein K09181 - - 0.0000000000000000000000000000000000002464 147.0
CMS2_k127_3440871_31 Domain related to MnhB subunit of Na+/H+ antiporter - - - 0.00000000000000000000000000000000003673 146.0
CMS2_k127_3440871_32 - - - - 0.000000000000000000000000000000005734 134.0
CMS2_k127_3440871_33 universal stress protein - - - 0.000000000000000000000000000000008162 134.0
CMS2_k127_3440871_34 Cytochrome c K08738 - - 0.00000000000000000000000000000003703 128.0
CMS2_k127_3440871_35 helix_turn_helix, cAMP Regulatory protein K21563 - - 0.000000000000000000000000001429 123.0
CMS2_k127_3440871_36 PFAM Na H antiporter subunit K05571 - - 0.0000000000000000000000001487 109.0
CMS2_k127_3440871_37 Cation antiporter K05569 - - 0.00000000000000000000009718 115.0
CMS2_k127_3440871_38 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.0000000000000000000001684 109.0
CMS2_k127_3440871_39 Domain related to MnhB subunit of Na+/H+ antiporter - - - 0.000000000000000000001057 101.0
CMS2_k127_3440871_4 Cytochrome b(N-terminal)/b6/petB - - - 6.78e-228 722.0
CMS2_k127_3440871_40 Universal stress protein - - - 0.00000000000000000007147 100.0
CMS2_k127_3440871_41 lipid carrier protein - - - 0.00000000000000001743 95.0
CMS2_k127_3440871_42 response regulator - - - 0.0000000000000000542 89.0
CMS2_k127_3440871_43 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05570 - - 0.00000000000004552 81.0
CMS2_k127_3440871_44 - - - - 0.0000000000001765 71.0
CMS2_k127_3440871_45 Uncharacterized conserved protein (DUF2249) - - - 0.000000005757 68.0
CMS2_k127_3440871_5 cytochrome - - - 3.267e-214 690.0
CMS2_k127_3440871_6 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 6.457e-196 620.0
CMS2_k127_3440871_7 Proton-conducting membrane transporter K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 594.0
CMS2_k127_3440871_8 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 539.0
CMS2_k127_3440871_9 PFAM Glycoside hydrolase family 65, central catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 503.0
CMS2_k127_3445869_0 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 5.521e-199 633.0
CMS2_k127_3445869_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.264e-195 616.0
CMS2_k127_3445869_2 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 517.0
CMS2_k127_3445869_3 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 451.0
CMS2_k127_3445869_4 amino acid transport system, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 423.0
CMS2_k127_3445869_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 308.0
CMS2_k127_3445869_6 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000002572 247.0
CMS2_k127_3445869_7 Protein of unknown function (DUF1289) - - - 0.00000000003291 71.0
CMS2_k127_3526668_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 410.0
CMS2_k127_3526668_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 322.0
CMS2_k127_3526668_2 Protein conserved in bacteria K07793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 292.0
CMS2_k127_3526668_3 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000001641 111.0
CMS2_k127_3531316_0 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 499.0
CMS2_k127_3531316_1 Protein of unknown function DUF126 K09128 - - 0.00000000000000000000000000002383 118.0
CMS2_k127_3531316_2 (Lipo)protein - - - 0.0000000000000007727 84.0
CMS2_k127_3575789_0 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 1.376e-203 665.0
CMS2_k127_3575789_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 374.0
CMS2_k127_3575789_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000008662 153.0
CMS2_k127_3575789_3 Universal stress protein - - - 0.000000000000000000000003087 109.0
CMS2_k127_3575789_4 cytochrome oxidase maturation protein cbb3-type - - - 0.000000000008715 74.0
CMS2_k127_3604016_0 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 4.111e-221 692.0
CMS2_k127_3604016_1 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 446.0
CMS2_k127_36145_0 Flavin containing amine oxidoreductase K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 312.0
CMS2_k127_3617715_0 Glycosyl hydrolase family 65, C-terminal domain K01838,K05342 - 2.4.1.64,5.4.2.6 0.0 1070.0
CMS2_k127_3617715_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.092e-254 798.0
CMS2_k127_3617715_10 Planctomycete cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 302.0
CMS2_k127_3617715_11 Protein of unknown function, DUF480 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003041 268.0
CMS2_k127_3617715_12 SCO1/SenC - - - 0.000000000000000000000000000000000000000000000000000000000000000000008183 242.0
CMS2_k127_3617715_13 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001786 258.0
CMS2_k127_3617715_14 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000004683 233.0
CMS2_k127_3617715_15 prepilin-type N-terminal cleavage methylation K02456 - - 0.000000000000000000000000000000000000000000000000000000000007468 211.0
CMS2_k127_3617715_16 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000002117 205.0
CMS2_k127_3617715_17 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000000001039 198.0
CMS2_k127_3617715_18 GDYXXLXY protein - - - 0.00000000000000000000000000000000000000000000000000002192 213.0
CMS2_k127_3617715_19 Type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000001748 160.0
CMS2_k127_3617715_2 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 3.526e-206 674.0
CMS2_k127_3617715_20 Type II secretory pathway pseudopilin - - - 0.00000000000000000000000000000000001437 145.0
CMS2_k127_3617715_21 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000331 125.0
CMS2_k127_3617715_22 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000006712 134.0
CMS2_k127_3617715_23 sequence-specific DNA binding K13280 - 3.4.21.89 0.00000000000000000000000002763 113.0
CMS2_k127_3617715_24 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000009071 101.0
CMS2_k127_3617715_25 - - - - 0.0000000000000000006731 90.0
CMS2_k127_3617715_26 - - - - 0.000000000000000007729 93.0
CMS2_k127_3617715_27 Type II secretion system (T2SS), protein M subtype b - - - 0.00000000000000004004 94.0
CMS2_k127_3617715_28 - - - - 0.00000000000002765 83.0
CMS2_k127_3617715_29 Multicopper oxidase K22349 - 1.16.3.3 0.00000000000005362 72.0
CMS2_k127_3617715_3 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 4.595e-205 660.0
CMS2_k127_3617715_30 - - - - 0.000001637 60.0
CMS2_k127_3617715_4 Secretin and TonB N terminus short domain K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 593.0
CMS2_k127_3617715_5 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 449.0
CMS2_k127_3617715_6 PFAM type II secretion system K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008846 381.0
CMS2_k127_3617715_7 PFAM Thiamine pyrophosphate K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 359.0
CMS2_k127_3617715_8 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 353.0
CMS2_k127_3617715_9 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 308.0
CMS2_k127_3622987_0 Asparagine synthase K01953 - 6.3.5.4 1.325e-263 823.0
CMS2_k127_3622987_1 Cyanophycin synthetase - - - 5.918e-253 796.0
CMS2_k127_3622987_10 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 0.000173 47.0
CMS2_k127_3622987_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.413e-237 742.0
CMS2_k127_3622987_3 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 489.0
CMS2_k127_3622987_4 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 475.0
CMS2_k127_3622987_5 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 375.0
CMS2_k127_3622987_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 328.0
CMS2_k127_3622987_7 COG1363 Cellulase M and related proteins - - - 0.00000000000000000000000000000000000000000000000001049 198.0
CMS2_k127_3622987_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000001101 132.0
CMS2_k127_3622987_9 M42 glutamyl aminopeptidase - - - 0.00000000000000000007047 94.0
CMS2_k127_3646739_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1341.0
CMS2_k127_3646739_1 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 2.118e-276 865.0
CMS2_k127_3646739_10 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000003199 90.0
CMS2_k127_3646739_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 5.618e-207 655.0
CMS2_k127_3646739_3 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 541.0
CMS2_k127_3646739_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 451.0
CMS2_k127_3646739_5 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 319.0
CMS2_k127_3646739_6 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000004664 243.0
CMS2_k127_3646739_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000007494 204.0
CMS2_k127_3646739_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000001429 166.0
CMS2_k127_3646739_9 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000001573 138.0
CMS2_k127_3672846_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 5.962e-231 732.0
CMS2_k127_3672846_1 ABC transporter C-terminal domain K15738 - - 5.493e-196 628.0
CMS2_k127_3672846_10 RelE toxin of RelE / RelB toxin-antitoxin system - - - 0.0000000000000000000000000000000000000000009233 160.0
CMS2_k127_3672846_11 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000009304 132.0
CMS2_k127_3672846_12 - - - - 0.000000000000000000000000000002072 126.0
CMS2_k127_3672846_13 - - - - 0.00000000000000000000006038 109.0
CMS2_k127_3672846_14 - - - - 0.000000000000000000002365 106.0
CMS2_k127_3672846_15 Adenylate and Guanylate cyclase catalytic domain - - - 0.000003131 58.0
CMS2_k127_3672846_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 408.0
CMS2_k127_3672846_3 CRP FNR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005164 325.0
CMS2_k127_3672846_4 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001091 302.0
CMS2_k127_3672846_5 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006824 275.0
CMS2_k127_3672846_6 - - - - 0.000000000000000000000000000000000000000000000000000000000002415 213.0
CMS2_k127_3672846_7 Nucleotidyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000004822 208.0
CMS2_k127_3672846_8 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000008461 213.0
CMS2_k127_3672846_9 - - - - 0.0000000000000000000000000000000000000000000000000000007349 202.0
CMS2_k127_369248_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.884e-300 929.0
CMS2_k127_369248_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 1.978e-215 673.0
CMS2_k127_369248_10 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 395.0
CMS2_k127_369248_11 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 404.0
CMS2_k127_369248_12 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 375.0
CMS2_k127_369248_13 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 368.0
CMS2_k127_369248_14 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 347.0
CMS2_k127_369248_15 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 334.0
CMS2_k127_369248_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 322.0
CMS2_k127_369248_17 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009596 302.0
CMS2_k127_369248_18 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000001269 259.0
CMS2_k127_369248_19 MucB/RseB C-terminal domain K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003186 265.0
CMS2_k127_369248_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.609e-212 697.0
CMS2_k127_369248_20 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000688 241.0
CMS2_k127_369248_21 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000001027 238.0
CMS2_k127_369248_22 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000001325 244.0
CMS2_k127_369248_23 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000005027 226.0
CMS2_k127_369248_24 dna polymerase iii K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000006088 225.0
CMS2_k127_369248_25 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000009052 225.0
CMS2_k127_369248_26 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000003638 226.0
CMS2_k127_369248_27 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000001466 193.0
CMS2_k127_369248_28 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000001166 179.0
CMS2_k127_369248_29 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000916 150.0
CMS2_k127_369248_3 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.204e-206 658.0
CMS2_k127_369248_30 FecR protein - - - 0.00000000000000000000000000000000000312 142.0
CMS2_k127_369248_31 Protein of unknown function (DUF1178) - - - 0.00000000000000000000000000000000002391 139.0
CMS2_k127_369248_32 OmpA family - - - 0.0000000000000000000000000000000001132 141.0
CMS2_k127_369248_33 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000002596 133.0
CMS2_k127_369248_34 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000004547 125.0
CMS2_k127_369248_35 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000001139 87.0
CMS2_k127_369248_36 Histidine kinase-like ATPase domain - - - 0.000000000000005467 80.0
CMS2_k127_369248_37 Anti sigma-E protein RseA, N-terminal domain K03597 - - 0.000000000000006029 83.0
CMS2_k127_369248_38 Domain of unknown function (DUF4845) - - - 0.0000000000001418 77.0
CMS2_k127_369248_39 Glutaredoxin-like domain (DUF836) - - - 0.000000000002524 70.0
CMS2_k127_369248_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 7.013e-195 619.0
CMS2_k127_369248_41 Belongs to the SAICAR synthetase family K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.0000007529 52.0
CMS2_k127_369248_43 - - - - 0.0003393 52.0
CMS2_k127_369248_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 529.0
CMS2_k127_369248_6 COG2309 Leucyl aminopeptidase (aminopeptidase T) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 488.0
CMS2_k127_369248_7 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 470.0
CMS2_k127_369248_8 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 421.0
CMS2_k127_369248_9 Pyridoxal phosphate biosynthesis protein PdxJ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 400.0
CMS2_k127_3718346_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 548.0
CMS2_k127_3718346_1 MotA TolQ ExbB proton channel family K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 306.0
CMS2_k127_3718346_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009172 307.0
CMS2_k127_3718346_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000004901 210.0
CMS2_k127_3718346_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000104 180.0
CMS2_k127_3718346_5 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000008997 170.0
CMS2_k127_3718346_6 TonB C terminal K03646 - - 0.00000000000000000000000000000000000000001363 168.0
CMS2_k127_3718346_7 Acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000002153 135.0
CMS2_k127_3718346_8 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000002695 136.0
CMS2_k127_3876278_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.391e-314 980.0
CMS2_k127_3876278_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.857e-282 895.0
CMS2_k127_3876278_10 rieske 2fe-2s K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 483.0
CMS2_k127_3876278_11 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 454.0
CMS2_k127_3876278_12 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 460.0
CMS2_k127_3876278_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 424.0
CMS2_k127_3876278_14 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 438.0
CMS2_k127_3876278_15 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 404.0
CMS2_k127_3876278_16 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 397.0
CMS2_k127_3876278_17 Malonyl-CoA decarboxylase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008122 390.0
CMS2_k127_3876278_18 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 356.0
CMS2_k127_3876278_19 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 361.0
CMS2_k127_3876278_2 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 7.911e-238 740.0
CMS2_k127_3876278_20 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 366.0
CMS2_k127_3876278_21 dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 357.0
CMS2_k127_3876278_22 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 314.0
CMS2_k127_3876278_23 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 308.0
CMS2_k127_3876278_24 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 309.0
CMS2_k127_3876278_25 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 310.0
CMS2_k127_3876278_26 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 288.0
CMS2_k127_3876278_27 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003157 284.0
CMS2_k127_3876278_28 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000073 277.0
CMS2_k127_3876278_29 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001434 271.0
CMS2_k127_3876278_3 Bacterial transcriptional activator domain - - - 4.455e-200 664.0
CMS2_k127_3876278_30 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003585 276.0
CMS2_k127_3876278_31 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000001379 246.0
CMS2_k127_3876278_32 gag-polyprotein putative aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000000000000000001964 201.0
CMS2_k127_3876278_33 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000002052 208.0
CMS2_k127_3876278_34 Hydrolase, P-loop family K06925 - - 0.000000000000000000000000000000000000000000002593 168.0
CMS2_k127_3876278_35 TIGRFAM Carbohydrate kinase, thermoresistant glucokinase K00851 - 2.7.1.12 0.00000000000000000000000000000000000009514 158.0
CMS2_k127_3876278_36 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000007822 150.0
CMS2_k127_3876278_37 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000009792 128.0
CMS2_k127_3876278_38 Protein of unknown function (DUF2877) - - - 0.00000000000000000000000008635 118.0
CMS2_k127_3876278_39 - - - - 0.000000000000000000000000327 111.0
CMS2_k127_3876278_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 627.0
CMS2_k127_3876278_40 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000001155 79.0
CMS2_k127_3876278_41 Belongs to the UPF0434 family K09791 - - 0.000000000000007078 77.0
CMS2_k127_3876278_42 helix_turn_helix, Lux Regulon K07684,K07693 - - 0.00000000000134 71.0
CMS2_k127_3876278_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 601.0
CMS2_k127_3876278_6 Protein of unknown function (DUF1116) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 599.0
CMS2_k127_3876278_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 557.0
CMS2_k127_3876278_8 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 551.0
CMS2_k127_3876278_9 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 505.0
CMS2_k127_3879723_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.652e-299 925.0
CMS2_k127_3879723_1 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 2.124e-235 742.0
CMS2_k127_3879723_10 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000007486 264.0
CMS2_k127_3879723_11 - - - - 0.000000000000000000000000000000000000000000000001737 190.0
CMS2_k127_3879723_12 cytochrome c5 - - - 0.00000000000000000000000000000000000000000000001491 184.0
CMS2_k127_3879723_13 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.00000000000000000000000000000000000000000002621 164.0
CMS2_k127_3879723_14 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000009957 130.0
CMS2_k127_3879723_15 Cytochrome c - - - 0.000000000000000000000000000001329 133.0
CMS2_k127_3879723_16 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.000000000000000000000000000004623 130.0
CMS2_k127_3879723_17 Cytochrome c - - - 0.000000000000000000000000001355 126.0
CMS2_k127_3879723_18 Cytochrome c - - - 0.0000000000000000000000003201 124.0
CMS2_k127_3879723_19 - - - - 0.000000000000000003767 96.0
CMS2_k127_3879723_2 Cytochrome c554 and c-prime - - - 2.764e-229 731.0
CMS2_k127_3879723_20 Cytochrome c K08738 - - 0.00000000000001158 77.0
CMS2_k127_3879723_21 Cytochrome c K08738 - - 0.00000002899 66.0
CMS2_k127_3879723_22 cytochrome - - - 0.000001543 62.0
CMS2_k127_3879723_23 cytochrome C K08738 - - 0.0001785 55.0
CMS2_k127_3879723_3 Aminotransferase class I and II K14261 - - 4.353e-224 698.0
CMS2_k127_3879723_4 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00169 - 1.2.7.1 1.11e-197 626.0
CMS2_k127_3879723_5 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 632.0
CMS2_k127_3879723_6 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 593.0
CMS2_k127_3879723_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K18356 - 1.2.1.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 548.0
CMS2_k127_3879723_8 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 329.0
CMS2_k127_3879723_9 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007626 293.0
CMS2_k127_3934184_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 6.868e-208 663.0
CMS2_k127_3934184_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 545.0
CMS2_k127_3934184_10 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000001276 269.0
CMS2_k127_3934184_11 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000006878 257.0
CMS2_k127_3934184_12 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000001892 234.0
CMS2_k127_3934184_13 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000008394 176.0
CMS2_k127_3934184_14 - - - - 0.0000000000000000000000000000000000000000001377 166.0
CMS2_k127_3934184_15 LrgA family K06518 - - 0.00000000000000000000000000000002254 128.0
CMS2_k127_3934184_16 Cupin 2, conserved barrel K21700 - - 0.0000000000000000000000000000001802 126.0
CMS2_k127_3934184_17 - - - - 0.00000000000000000002989 102.0
CMS2_k127_3934184_18 Protein of unknown function (DUF3567) - - - 0.00000002025 62.0
CMS2_k127_3934184_2 Serine aminopeptidase, S33 K01253,K08253 - 2.7.10.2,3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 514.0
CMS2_k127_3934184_3 Protein of unknown function (DUF2817) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 423.0
CMS2_k127_3934184_4 PFAM multi antimicrobial extrusion protein MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 375.0
CMS2_k127_3934184_5 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 357.0
CMS2_k127_3934184_6 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 327.0
CMS2_k127_3934184_7 LrgB-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 316.0
CMS2_k127_3934184_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 308.0
CMS2_k127_3934184_9 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000003888 254.0
CMS2_k127_3934542_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 588.0
CMS2_k127_3934542_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 464.0
CMS2_k127_3934542_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 454.0
CMS2_k127_3934542_3 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 368.0
CMS2_k127_3934542_4 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 353.0
CMS2_k127_3934542_5 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 284.0
CMS2_k127_3978073_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 2.612e-262 835.0
CMS2_k127_3978073_1 enoyl-CoA hydratase K15513 - 4.1.2.44 1.264e-227 728.0
CMS2_k127_3978073_10 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000008044 216.0
CMS2_k127_3978073_11 Flavodoxin K06205 - - 0.0000000000000000000000000000000000000000003012 166.0
CMS2_k127_3978073_12 Glycine-zipper domain - - - 0.000000000000000000000000000000000000001109 157.0
CMS2_k127_3978073_13 - - - - 0.000000000000000000000000000006406 124.0
CMS2_k127_3978073_14 Transcriptional regulator - - - 0.000000000000000000000004461 109.0
CMS2_k127_3978073_15 - - - - 0.00000000000000005493 85.0
CMS2_k127_3978073_2 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 1.676e-218 695.0
CMS2_k127_3978073_3 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 520.0
CMS2_k127_3978073_4 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 378.0
CMS2_k127_3978073_5 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 325.0
CMS2_k127_3978073_6 Shikimate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003926 248.0
CMS2_k127_3978073_7 cysteine dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001759 240.0
CMS2_k127_3978073_8 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000000000001465 237.0
CMS2_k127_3978073_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000001357 228.0
CMS2_k127_407008_0 NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 0.0 1041.0
CMS2_k127_407008_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.568e-271 846.0
CMS2_k127_407008_10 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 304.0
CMS2_k127_407008_11 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001138 279.0
CMS2_k127_407008_12 PFAM Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000002845 251.0
CMS2_k127_407008_13 Electron transfer DM13 - - - 0.0000000000000000000000000000000000000000000000000000000000000001545 227.0
CMS2_k127_407008_14 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000002561 227.0
CMS2_k127_407008_15 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000436 209.0
CMS2_k127_407008_16 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000008991 218.0
CMS2_k127_407008_17 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000001102 212.0
CMS2_k127_407008_18 PFAM regulatory protein, MarR - - - 0.00000000000000000000000000000000000000000000000000007177 191.0
CMS2_k127_407008_19 - - - - 0.00000000000000000000000000000000000000000000000001166 192.0
CMS2_k127_407008_2 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 1.673e-228 737.0
CMS2_k127_407008_20 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000001575 170.0
CMS2_k127_407008_21 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000008484 175.0
CMS2_k127_407008_22 Thioredoxin - - - 0.0000000000000000000000000000000000000426 146.0
CMS2_k127_407008_23 PFAM Cupin 2, conserved barrel - - - 0.000000000000000000000000000000000000124 145.0
CMS2_k127_407008_24 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000003739 121.0
CMS2_k127_407008_25 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000006968 124.0
CMS2_k127_407008_26 PFAM Cell Wall Hydrolase - - - 0.0000000000000000000006048 103.0
CMS2_k127_407008_27 AMP-binding enzyme K12508 - 6.2.1.34 0.000000008631 57.0
CMS2_k127_407008_3 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 456.0
CMS2_k127_407008_4 FAD binding domain K00480,K22270 - 1.14.13.1,1.14.13.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 455.0
CMS2_k127_407008_5 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 417.0
CMS2_k127_407008_6 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 404.0
CMS2_k127_407008_7 Dehydrogenase K15054 - 1.1.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 392.0
CMS2_k127_407008_8 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 379.0
CMS2_k127_407008_9 phosphogluconate dehydrogenase (decarboxylating) activity K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 335.0
CMS2_k127_4072587_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1632.0
CMS2_k127_4072587_1 Domain of unknown function (DUF3394) - - - 1.285e-307 955.0
CMS2_k127_4072587_10 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 541.0
CMS2_k127_4072587_11 Type II secretion system (T2SS), protein F K02455,K12278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 485.0
CMS2_k127_4072587_12 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 460.0
CMS2_k127_4072587_13 Fe-S type, tartrate fumarate subfamily, alpha subunit K03779 - 4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 434.0
CMS2_k127_4072587_14 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 436.0
CMS2_k127_4072587_15 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 432.0
CMS2_k127_4072587_16 Tyrosine recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 371.0
CMS2_k127_4072587_17 AAA domain K02450,K12283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009938 368.0
CMS2_k127_4072587_18 Belongs to the LDH2 MDH2 oxidoreductase family K13609,K16844 - 1.1.1.338,1.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 368.0
CMS2_k127_4072587_19 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 355.0
CMS2_k127_4072587_2 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 2.098e-259 805.0
CMS2_k127_4072587_20 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 358.0
CMS2_k127_4072587_21 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 323.0
CMS2_k127_4072587_22 Fumarate K01678,K03780 - 4.2.1.2,4.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 322.0
CMS2_k127_4072587_23 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 301.0
CMS2_k127_4072587_24 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001286 278.0
CMS2_k127_4072587_25 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001283 282.0
CMS2_k127_4072587_26 Pilus assembly protein K12279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001159 265.0
CMS2_k127_4072587_27 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001118 262.0
CMS2_k127_4072587_28 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004743 250.0
CMS2_k127_4072587_29 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002595 229.0
CMS2_k127_4072587_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 4.3e-259 839.0
CMS2_k127_4072587_30 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000136 227.0
CMS2_k127_4072587_31 Domain of unknown function DUF108 K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000003423 229.0
CMS2_k127_4072587_32 Haemolysin-III related - - - 0.00000000000000000000000000000000000000000000000000000000000007029 223.0
CMS2_k127_4072587_33 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000001426 201.0
CMS2_k127_4072587_34 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000393 180.0
CMS2_k127_4072587_35 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000003859 176.0
CMS2_k127_4072587_36 endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000003295 169.0
CMS2_k127_4072587_37 carbon utilization K12280 - - 0.00000000000000000000000000000000000000002192 162.0
CMS2_k127_4072587_38 COG0350 Methylated DNA-protein cysteine methyltransferase K00567 - 2.1.1.63 0.00000000000000000000000000000000000000002386 157.0
CMS2_k127_4072587_39 type IV pilus modification protein PilV K10927 - - 0.0000000000000000000000000000000000000001354 156.0
CMS2_k127_4072587_4 COG1053 Succinate dehydrogenase fumarate reductase, flavoprotein subunit K00244 - 1.3.5.4 9.191e-246 771.0
CMS2_k127_4072587_40 -O-antigen K02847,K13009,K16705 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000004664 165.0
CMS2_k127_4072587_41 PFAM Fimbrial assembly family protein - - - 0.0000000000000000000000000000000000000648 151.0
CMS2_k127_4072587_42 SapC - - - 0.0000000000000000000000000000000000001418 151.0
CMS2_k127_4072587_43 Tetratricopeptide repeat K12284 - - 0.0000000000000000000000000000000000023 152.0
CMS2_k127_4072587_44 succinate dehydrogenase K00246 - - 0.00000000000000000000000000000002004 132.0
CMS2_k127_4072587_45 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000364 129.0
CMS2_k127_4072587_46 TPR repeat - - - 0.00000000000000000000000000000004863 128.0
CMS2_k127_4072587_47 Prokaryotic N-terminal methylation motif K12285 - - 0.000000000000000000000000000000709 133.0
CMS2_k127_4072587_48 - - - - 0.0000000000000000000000000002708 119.0
CMS2_k127_4072587_49 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000001029 125.0
CMS2_k127_4072587_5 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.748e-224 721.0
CMS2_k127_4072587_50 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.0000000000000000000000001015 115.0
CMS2_k127_4072587_51 SAF K16845 - 4.4.1.24 0.000000000000000000000005497 101.0
CMS2_k127_4072587_52 type II secretion system protein K K12286 - - 0.00000000000000000001228 99.0
CMS2_k127_4072587_53 phosphorelay signal transduction system - - - 0.0000000000000000000182 103.0
CMS2_k127_4072587_54 Predicted metal-dependent hydrolase K07044 - - 0.000000000000000001535 93.0
CMS2_k127_4072587_55 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000034 82.0
CMS2_k127_4072587_56 - K12281 - - 0.000000000000003279 80.0
CMS2_k127_4072587_57 general secretion pathway protein K02456 - - 0.0000000000007855 78.0
CMS2_k127_4072587_58 Tfp pilus assembly protein FimT K10926 - - 0.00000000001501 71.0
CMS2_k127_4072587_59 general secretion pathway protein K10924 - - 0.0000002825 59.0
CMS2_k127_4072587_6 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K12276 - - 6.568e-212 674.0
CMS2_k127_4072587_61 Transmembrane secretion effector - - - 0.000002467 50.0
CMS2_k127_4072587_7 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 535.0
CMS2_k127_4072587_8 type II and III secretion system protein K02453,K12282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 518.0
CMS2_k127_4072587_9 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006387 518.0
CMS2_k127_4103576_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1234.0
CMS2_k127_4103576_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.096e-216 677.0
CMS2_k127_4103576_10 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 402.0
CMS2_k127_4103576_11 glycosyl transferase, family 2 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 379.0
CMS2_k127_4103576_12 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 364.0
CMS2_k127_4103576_13 phytoene K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 344.0
CMS2_k127_4103576_14 MltA-interacting protein MipA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 320.0
CMS2_k127_4103576_15 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 335.0
CMS2_k127_4103576_16 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 289.0
CMS2_k127_4103576_17 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000156 284.0
CMS2_k127_4103576_18 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000002776 217.0
CMS2_k127_4103576_19 Peptidase M22 glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000000000000000000008006 219.0
CMS2_k127_4103576_2 Tryptophan halogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 599.0
CMS2_k127_4103576_20 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000002894 225.0
CMS2_k127_4103576_21 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000001899 188.0
CMS2_k127_4103576_22 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000000000000002493 160.0
CMS2_k127_4103576_23 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000001836 122.0
CMS2_k127_4103576_24 glucose sorbosone - - - 0.000000000000000000000000000002783 132.0
CMS2_k127_4103576_25 - - - - 0.0000000000001138 72.0
CMS2_k127_4103576_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 609.0
CMS2_k127_4103576_4 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 564.0
CMS2_k127_4103576_5 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 518.0
CMS2_k127_4103576_6 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 503.0
CMS2_k127_4103576_7 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 486.0
CMS2_k127_4103576_8 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 484.0
CMS2_k127_4103576_9 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 419.0
CMS2_k127_4114625_0 Dehydratase family K13875 - 4.2.1.25 2.563e-308 954.0
CMS2_k127_4114625_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 1.974e-225 711.0
CMS2_k127_4114625_10 PFAM ABC transporter related K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 291.0
CMS2_k127_4114625_11 PFAM fumarylacetoacetate (FAA) hydrolase K16856 - 4.3.2.3 0.00000000000000000000000000000000000000000000000000000007522 211.0
CMS2_k127_4114625_12 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000209 169.0
CMS2_k127_4114625_13 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000368 129.0
CMS2_k127_4114625_2 PFAM extracellular solute-binding protein family 1 K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 582.0
CMS2_k127_4114625_3 Belongs to the ABC transporter superfamily K02010,K10112 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 539.0
CMS2_k127_4114625_4 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 529.0
CMS2_k127_4114625_5 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 481.0
CMS2_k127_4114625_6 ABC-type sugar transport systems permease components K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 476.0
CMS2_k127_4114625_7 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005121 386.0
CMS2_k127_4114625_8 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 335.0
CMS2_k127_4114625_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009585 305.0
CMS2_k127_4118813_0 Activates fatty acids by binding to coenzyme A K00666,K01897 - 6.2.1.3 4.108e-213 675.0
CMS2_k127_4118813_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 445.0
CMS2_k127_4118813_2 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 384.0
CMS2_k127_4118813_3 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 285.0
CMS2_k127_4118813_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000002107 64.0
CMS2_k127_4120884_0 Histidine Phosphotransfer domain K10715 - 2.7.13.3 0.0 1086.0
CMS2_k127_4120884_1 HD domain K13815 - - 5.713e-198 621.0
CMS2_k127_4120884_2 Protein of unknown function (DUF3530) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 411.0
CMS2_k127_4120884_3 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 388.0
CMS2_k127_4120884_4 Pfam Enoyl-CoA hydratase isomerase K13816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 393.0
CMS2_k127_4120884_5 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 336.0
CMS2_k127_4124952_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 572.0
CMS2_k127_4124952_1 III protein, CoA-transferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 535.0
CMS2_k127_4124952_10 Acyl-CoA dehydrogenase, C-terminal domain K16047 - 1.14.14.12 0.000000000000003414 79.0
CMS2_k127_4124952_11 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000002203 80.0
CMS2_k127_4124952_12 EamA-like transporter family - - - 0.00008682 53.0
CMS2_k127_4124952_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006744 483.0
CMS2_k127_4124952_3 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 417.0
CMS2_k127_4124952_4 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 375.0
CMS2_k127_4124952_5 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005719 284.0
CMS2_k127_4124952_6 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000004334 270.0
CMS2_k127_4124952_7 protocatechuate 3,4-dioxygenase, beta subunit K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000001244 234.0
CMS2_k127_4124952_8 protocatechuate 3,4-dioxygenase K00448 - 1.13.11.3 0.000000000000000000000000000000000000000000003223 179.0
CMS2_k127_4124952_9 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000808 138.0
CMS2_k127_4129183_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 4.02e-210 681.0
CMS2_k127_4129183_1 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 300.0
CMS2_k127_4129183_2 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000004964 177.0
CMS2_k127_4129183_3 Dodecin K09165 - - 0.00000000000000000007002 106.0
CMS2_k127_4129183_4 lipoprotein releasing system, transmembrane protein, LolC E family K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0098796,GO:0098797 - 0.0000000000005864 70.0
CMS2_k127_4252502_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002154 268.0
CMS2_k127_4252502_1 oxidoreductase DsbE K02199 - - 0.000000000000000000000000000000000000000000000000000000000000000009615 228.0
CMS2_k127_4252502_2 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000003429 196.0
CMS2_k127_4252502_3 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000001372 148.0
CMS2_k127_4269487_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 599.0
CMS2_k127_4269487_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009446 466.0
CMS2_k127_4269487_2 membrane-bound lytic murein transglycosylase K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 394.0
CMS2_k127_4269487_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 331.0
CMS2_k127_4269487_4 Ubiquinone biosynthesis hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 317.0
CMS2_k127_4269487_5 PFAM Glutamine amidotransferase class-I K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 286.0
CMS2_k127_4269487_6 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000004638 205.0
CMS2_k127_4269487_7 ApaG domain - - - 0.00000000000000000000000000000000000000000000000000000002067 201.0
CMS2_k127_4269487_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000009897 201.0
CMS2_k127_4286619_0 NAD NADP octopine nopaline dehydrogenase K04940 - 1.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 372.0
CMS2_k127_4286619_1 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000000000000000000000000006062 203.0
CMS2_k127_4286619_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000267 62.0
CMS2_k127_4321827_0 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 618.0
CMS2_k127_4321827_1 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008051 340.0
CMS2_k127_4321827_2 heptosyltransferase K12982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 293.0
CMS2_k127_4321827_3 EVE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009229 241.0
CMS2_k127_4321827_4 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001286 240.0
CMS2_k127_4321827_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000001551 243.0
CMS2_k127_4321827_6 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000004102 122.0
CMS2_k127_4321827_7 - - - - 0.000000007235 59.0
CMS2_k127_4351043_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.69e-202 640.0
CMS2_k127_4351043_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000305 89.0
CMS2_k127_4392548_0 Domain of unknown function (DUF3400) - - - 0.0 1675.0
CMS2_k127_4392548_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1162.0
CMS2_k127_4392548_10 - - - - 0.00000000000000004212 95.0
CMS2_k127_4392548_2 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 1.293e-204 644.0
CMS2_k127_4392548_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 432.0
CMS2_k127_4392548_4 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 386.0
CMS2_k127_4392548_5 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 346.0
CMS2_k127_4392548_6 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000002469 241.0
CMS2_k127_4392548_7 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000006015 218.0
CMS2_k127_4392548_8 - - - - 0.0000000000000000000000000000000004705 144.0
CMS2_k127_4392548_9 Redoxin domain protein - - - 0.0000000000000000000000001919 111.0
CMS2_k127_4411041_0 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 342.0
CMS2_k127_4411041_1 Histidine triad (Hit) protein K02503 - - 0.00000000000000000000000000000000000000000001029 169.0
CMS2_k127_4411041_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000001933 101.0
CMS2_k127_4411041_3 Tellurite resistance protein TerB - - - 0.000000000000000001284 99.0
CMS2_k127_4487927_0 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 9.836e-230 720.0
CMS2_k127_4487927_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.783e-194 616.0
CMS2_k127_4487927_10 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000005487 204.0
CMS2_k127_4487927_11 Small Multidrug Resistance protein - - - 0.0000000000000000000000000000000000000002504 154.0
CMS2_k127_4487927_12 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000000031 140.0
CMS2_k127_4487927_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000716 138.0
CMS2_k127_4487927_14 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000003018 102.0
CMS2_k127_4487927_15 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.000000000000000296 87.0
CMS2_k127_4487927_16 Protein of unknown function (DUF498/DUF598) - - - 0.000000001593 59.0
CMS2_k127_4487927_2 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 519.0
CMS2_k127_4487927_3 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000078 417.0
CMS2_k127_4487927_4 COG3639 ABC-type phosphate phosphonate transport system, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 409.0
CMS2_k127_4487927_5 COG3639 ABC-type phosphate phosphonate transport system, permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 407.0
CMS2_k127_4487927_6 Maleate cis-trans isomerase K01799 - 5.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002954 262.0
CMS2_k127_4487927_7 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000002584 234.0
CMS2_k127_4487927_8 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000000001124 244.0
CMS2_k127_4487927_9 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000000003679 201.0
CMS2_k127_4496965_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1243.0
CMS2_k127_4496965_1 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 306.0
CMS2_k127_4496965_10 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000003755 249.0
CMS2_k127_4496965_11 cheY-homologous receiver domain - - - 0.000000000000000000000000000001427 124.0
CMS2_k127_4496965_12 asparaginase K01424,K13051 GO:0003674,GO:0003824,GO:0004067,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008798,GO:0010467,GO:0016485,GO:0016540,GO:0016787,GO:0016810,GO:0016811,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.19.5,3.5.1.1 0.000000000000000000000001433 112.0
CMS2_k127_4496965_13 (Hpt) domain - - - 0.00000000000000000758 87.0
CMS2_k127_4496965_14 Domain of unknown function (DUF4156) - - - 0.000000000000000009566 87.0
CMS2_k127_4496965_15 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053 - - 0.0000000000000001182 89.0
CMS2_k127_4496965_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 309.0
CMS2_k127_4496965_3 DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 301.0
CMS2_k127_4496965_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K10715 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006256 291.0
CMS2_k127_4496965_5 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000007957 272.0
CMS2_k127_4496965_6 COG2202 FOG PAS PAC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002521 278.0
CMS2_k127_4496965_7 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000447 257.0
CMS2_k127_4496965_8 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000727 259.0
CMS2_k127_4496965_9 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005096 256.0
CMS2_k127_4504626_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0 1016.0
CMS2_k127_4504626_1 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 3.491e-215 680.0
CMS2_k127_4504626_10 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 336.0
CMS2_k127_4504626_11 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 317.0
CMS2_k127_4504626_12 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001087 285.0
CMS2_k127_4504626_13 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004304 261.0
CMS2_k127_4504626_14 Conserved TM helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000008478 238.0
CMS2_k127_4504626_15 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000005633 221.0
CMS2_k127_4504626_16 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000003598 218.0
CMS2_k127_4504626_17 membrane - - - 0.00000000000000000000000000000000000000000000000000000000001717 212.0
CMS2_k127_4504626_18 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000002234 190.0
CMS2_k127_4504626_19 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000004662 190.0
CMS2_k127_4504626_2 Amidohydrolase family - - - 1.471e-204 649.0
CMS2_k127_4504626_20 - - - - 0.0000000000000000000000000000002579 129.0
CMS2_k127_4504626_21 Cold shock protein K03704 - - 0.0000000000000000000000000009785 116.0
CMS2_k127_4504626_22 Rubrerythrin - - - 0.000000000000000000003207 100.0
CMS2_k127_4504626_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 501.0
CMS2_k127_4504626_4 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 497.0
CMS2_k127_4504626_5 Cache 3/Cache 2 fusion domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 460.0
CMS2_k127_4504626_6 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 422.0
CMS2_k127_4504626_7 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 414.0
CMS2_k127_4504626_8 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 405.0
CMS2_k127_4504626_9 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 340.0
CMS2_k127_4505377_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 3.68e-278 874.0
CMS2_k127_4505377_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.249e-234 738.0
CMS2_k127_4505377_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 4.557e-227 710.0
CMS2_k127_4505377_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 316.0
CMS2_k127_4505377_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002388 285.0
CMS2_k127_4505377_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000002518 237.0
CMS2_k127_4505377_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000118 205.0
CMS2_k127_4505377_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000003182 148.0
CMS2_k127_4515366_0 PFAM fumarate lyase K01756,K01857 - 4.3.2.2,5.5.1.2 1.337e-210 670.0
CMS2_k127_4515366_1 phosphonoacetate hydrolase K19670 - 3.11.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 588.0
CMS2_k127_4515366_10 Esterase PHB depolymerase K03932 - - 0.00000000000000000000000000000000000000000289 168.0
CMS2_k127_4515366_11 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.00000000000000000000000000004279 117.0
CMS2_k127_4515366_12 AMP-binding enzyme C-terminal domain - - - 0.0001211 45.0
CMS2_k127_4515366_2 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 438.0
CMS2_k127_4515366_3 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 427.0
CMS2_k127_4515366_4 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 426.0
CMS2_k127_4515366_5 PFAM Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 407.0
CMS2_k127_4515366_6 - - - - 0.00000000000000000000000000000000000000000000000000004078 200.0
CMS2_k127_4515366_7 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000004369 184.0
CMS2_k127_4515366_8 - - - - 0.0000000000000000000000000000000000000000000000112 175.0
CMS2_k127_4515366_9 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.000000000000000000000000000000000000000001769 157.0
CMS2_k127_452509_0 FAD linked oxidase domain protein K06911 - - 3.068e-200 648.0
CMS2_k127_452509_1 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 494.0
CMS2_k127_452509_2 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 371.0
CMS2_k127_452509_3 Peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 377.0
CMS2_k127_452509_4 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 320.0
CMS2_k127_452509_5 COG0501 Zn-dependent protease with chaperone function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 324.0
CMS2_k127_452509_6 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001042 253.0
CMS2_k127_4539075_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 411.0
CMS2_k127_4539075_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 373.0
CMS2_k127_4539075_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 341.0
CMS2_k127_4539075_3 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000002647 183.0
CMS2_k127_4543901_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 1.231e-242 766.0
CMS2_k127_4543901_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 514.0
CMS2_k127_4543901_10 Protein of unknown function (DUF560) - - - 0.0000000000000000000000000000000000000000000000003437 192.0
CMS2_k127_4543901_11 C-lobe and N-lobe beta barrels of Tf-binding protein B - - - 0.00000000000000000003006 104.0
CMS2_k127_4543901_12 C-lobe and N-lobe beta barrels of Tf-binding protein B - - - 0.00000000000000000003917 103.0
CMS2_k127_4543901_13 response regulator - - - 0.000000002977 69.0
CMS2_k127_4543901_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 387.0
CMS2_k127_4543901_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 319.0
CMS2_k127_4543901_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 281.0
CMS2_k127_4543901_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003994 261.0
CMS2_k127_4543901_6 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002947 256.0
CMS2_k127_4543901_7 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000002559 259.0
CMS2_k127_4543901_8 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000004289 232.0
CMS2_k127_4543901_9 - - - - 0.00000000000000000000000000000000000000000000000000003104 197.0
CMS2_k127_4557007_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 446.0
CMS2_k127_4557007_1 OsmC-like protein K06889,K07397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 446.0
CMS2_k127_4557007_10 - - - - 0.0000000000000000000000009598 109.0
CMS2_k127_4557007_11 Transposase - - - 0.0002197 47.0
CMS2_k127_4557007_2 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 442.0
CMS2_k127_4557007_3 Transcriptional regulator K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 391.0
CMS2_k127_4557007_4 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 390.0
CMS2_k127_4557007_5 (Lipo)protein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 381.0
CMS2_k127_4557007_6 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 309.0
CMS2_k127_4557007_7 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000007056 212.0
CMS2_k127_4557007_8 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000007899 194.0
CMS2_k127_4557007_9 - - - - 0.000000000000000000000000000001853 124.0
CMS2_k127_4606732_0 succinate dehydrogenase fumarate reductase, flavoprotein subunit - - - 6.067e-232 730.0
CMS2_k127_4606732_1 TRAP transporter, 4TM 12TM fusion protein - - - 1.549e-215 694.0
CMS2_k127_4606732_2 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K20940 - 1.14.13.218 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 542.0
CMS2_k127_4606732_3 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000006226 168.0
CMS2_k127_4606732_4 Amidase - - - 0.0000000000000005889 92.0
CMS2_k127_4631430_0 NADH ubiquinone plastoquinone (Complex I) - - - 4.627e-299 935.0
CMS2_k127_4631430_1 Proton-conducting membrane transporter K12141 - - 2.775e-242 756.0
CMS2_k127_4631430_10 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000001166 199.0
CMS2_k127_4631430_11 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000007293 159.0
CMS2_k127_4631430_12 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07226 - - 0.0000000000000000002729 94.0
CMS2_k127_4631430_13 KTSC domain - - - 0.000000007427 67.0
CMS2_k127_4631430_2 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 1.37e-212 675.0
CMS2_k127_4631430_3 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 2.83e-204 662.0
CMS2_k127_4631430_4 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 479.0
CMS2_k127_4631430_5 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 419.0
CMS2_k127_4631430_6 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 446.0
CMS2_k127_4631430_7 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008259 316.0
CMS2_k127_4631430_8 Belongs to the GST superfamily K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007329 276.0
CMS2_k127_4631430_9 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001253 260.0
CMS2_k127_4637999_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 0.0 1731.0
CMS2_k127_4637999_1 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1676.0
CMS2_k127_4637999_10 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000000000005189 173.0
CMS2_k127_4637999_11 PFAM GYD family protein - - - 0.00000000000000000000000000002832 120.0
CMS2_k127_4637999_12 translation initiation factor activity - - - 0.0000000000000000000000000006752 132.0
CMS2_k127_4637999_2 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 589.0
CMS2_k127_4637999_3 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000749 550.0
CMS2_k127_4637999_4 Fad dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 491.0
CMS2_k127_4637999_5 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 432.0
CMS2_k127_4637999_6 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 337.0
CMS2_k127_4637999_7 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000876 302.0
CMS2_k127_4637999_8 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000003622 192.0
CMS2_k127_4637999_9 transport system small permease component - - - 0.0000000000000000000000000000000000000000000000000002852 190.0
CMS2_k127_4653655_0 Flavin-binding monooxygenase-like K07222 - - 8.923e-254 796.0
CMS2_k127_4653655_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 5.874e-233 737.0
CMS2_k127_4653655_10 SMP-30/Gluconolaconase/LRE-like region K13874,K14274 - 3.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 314.0
CMS2_k127_4653655_11 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 307.0
CMS2_k127_4653655_12 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001522 278.0
CMS2_k127_4653655_13 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000002236 193.0
CMS2_k127_4653655_14 3'-5' exonuclease - - - 0.000000000000000000000000000000000000000000000000001931 190.0
CMS2_k127_4653655_15 LemA family - - - 0.00000000000000000000000000000000000000000000003348 177.0
CMS2_k127_4653655_16 - - - - 0.000000000000000000000000000000000000000001058 159.0
CMS2_k127_4653655_17 Restriction endonuclease K07448 - - 0.000000000000000000000000000000000000001349 158.0
CMS2_k127_4653655_18 peptide chain release factor K15034 - - 0.000000000000000000000000000000000000002105 167.0
CMS2_k127_4653655_19 Glutaredoxin - - - 0.000000000000000000000000000000000000008919 160.0
CMS2_k127_4653655_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 1.722e-228 731.0
CMS2_k127_4653655_20 Cysteine dioxygenase type I - - - 0.0000000000000000000000000000000000001745 150.0
CMS2_k127_4653655_21 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000005769 141.0
CMS2_k127_4653655_22 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000008635 126.0
CMS2_k127_4653655_23 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000002294 125.0
CMS2_k127_4653655_24 nucleic acid-binding protein, contains PIN domain - - - 0.00000000000000000000000001548 118.0
CMS2_k127_4653655_25 - - - - 0.00000000000000000000000002545 113.0
CMS2_k127_4653655_26 PIN domain - - - 0.00000000000000000000003668 108.0
CMS2_k127_4653655_27 Protein of unknown function (DUF3293) - - - 0.0000000000000000001237 98.0
CMS2_k127_4653655_28 Alpha/beta hydrolase family - - - 0.00000000001368 70.0
CMS2_k127_4653655_29 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000003266 66.0
CMS2_k127_4653655_3 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 507.0
CMS2_k127_4653655_4 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 439.0
CMS2_k127_4653655_5 PFAM Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 399.0
CMS2_k127_4653655_6 Belongs to the D-glutamate cyclase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 362.0
CMS2_k127_4653655_7 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 376.0
CMS2_k127_4653655_8 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 329.0
CMS2_k127_4653655_9 carboxylic acid catabolic process K01856 - 5.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 312.0
CMS2_k127_4733548_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 537.0
CMS2_k127_4733548_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 487.0
CMS2_k127_4733548_10 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000002463 94.0
CMS2_k127_4733548_11 Alpha/beta hydrolase family - - - 0.00004136 57.0
CMS2_k127_4733548_2 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 396.0
CMS2_k127_4733548_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 316.0
CMS2_k127_4733548_4 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 297.0
CMS2_k127_4733548_5 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003358 303.0
CMS2_k127_4733548_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000009521 253.0
CMS2_k127_4733548_7 carboxylic ester hydrolase activity K01259,K19311 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000001941 233.0
CMS2_k127_4733548_8 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000002822 171.0
CMS2_k127_4733548_9 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000000000000000000000003807 130.0
CMS2_k127_4735084_0 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 4.499e-216 677.0
CMS2_k127_4735084_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.783e-194 619.0
CMS2_k127_4735084_10 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 361.0
CMS2_k127_4735084_11 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002726 276.0
CMS2_k127_4735084_12 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000433 261.0
CMS2_k127_4735084_13 Trap-type c4-dicarboxylate transport system, small permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000002639 238.0
CMS2_k127_4735084_14 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000001541 219.0
CMS2_k127_4735084_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000004234 179.0
CMS2_k127_4735084_16 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000003062 171.0
CMS2_k127_4735084_2 Protein of unknown function (DUF993) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 552.0
CMS2_k127_4735084_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 509.0
CMS2_k127_4735084_4 Mandelate Racemase Muconate Lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 479.0
CMS2_k127_4735084_5 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 469.0
CMS2_k127_4735084_6 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 449.0
CMS2_k127_4735084_7 PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal domain K18983 - 5.5.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008055 445.0
CMS2_k127_4735084_8 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 360.0
CMS2_k127_4735084_9 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 356.0
CMS2_k127_4735822_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 1.837e-311 974.0
CMS2_k127_4735822_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 8.666e-243 755.0
CMS2_k127_4735822_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 584.0
CMS2_k127_4737669_0 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 496.0
CMS2_k127_4737669_1 Protein of unknown function (DUF2914) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001582 281.0
CMS2_k127_4737669_2 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000002147 187.0
CMS2_k127_4737669_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000001871 106.0
CMS2_k127_4740283_0 Rieske [2Fe-2S] domain - - - 1.312e-197 636.0
CMS2_k127_4740283_1 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 318.0
CMS2_k127_4740283_2 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 321.0
CMS2_k127_4740283_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000002041 185.0
CMS2_k127_4740283_4 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000003367 87.0
CMS2_k127_4758143_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 587.0
CMS2_k127_4758143_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 586.0
CMS2_k127_4758143_2 ABC-type sugar transport system periplasmic component K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 542.0
CMS2_k127_4758143_3 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 524.0
CMS2_k127_4758143_4 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 454.0
CMS2_k127_4758143_5 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 429.0
CMS2_k127_4758143_6 probably responsible for the translocation of the substrate across the membrane K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 423.0
CMS2_k127_4758143_7 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 329.0
CMS2_k127_4758143_8 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000001051 118.0
CMS2_k127_4758143_9 Putative thioesterase (yiiD_Cterm) - - - 0.0000000000000000000002725 100.0
CMS2_k127_4770014_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 1.064e-217 689.0
CMS2_k127_4770014_1 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 474.0
CMS2_k127_4770014_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 467.0
CMS2_k127_4770014_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002411 287.0
CMS2_k127_4770014_4 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001433 252.0
CMS2_k127_4770014_5 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 0.000000000000000000000000000000000000000000000000000000000000002218 218.0
CMS2_k127_4770014_6 PFAM MaoC domain protein dehydratase - - - 0.0000000000000000000000000000000000000000000000000001434 191.0
CMS2_k127_4770014_7 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.000000000000000000000000000000000000000000000000002124 186.0
CMS2_k127_4833855_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 8.022e-298 928.0
CMS2_k127_4833855_1 ABC-type dipeptide transport system, periplasmic component K02035 - - 4.758e-232 731.0
CMS2_k127_4833855_10 PFAM 5-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 407.0
CMS2_k127_4833855_11 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 390.0
CMS2_k127_4833855_12 AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 404.0
CMS2_k127_4833855_13 Lipopolysaccharide export system ATP-binding protein K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 373.0
CMS2_k127_4833855_14 A G-specific K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 355.0
CMS2_k127_4833855_15 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 327.0
CMS2_k127_4833855_16 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 317.0
CMS2_k127_4833855_17 Putative methyltransferase K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000607 280.0
CMS2_k127_4833855_18 Stress-induced protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001032 281.0
CMS2_k127_4833855_19 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000002037 286.0
CMS2_k127_4833855_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 546.0
CMS2_k127_4833855_20 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001996 255.0
CMS2_k127_4833855_21 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000003374 234.0
CMS2_k127_4833855_22 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000002029 237.0
CMS2_k127_4833855_23 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000002323 215.0
CMS2_k127_4833855_24 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000004525 215.0
CMS2_k127_4833855_25 Peptidase S16, lon domain protein K07157 - - 0.0000000000000000000000000000000000000000000003351 183.0
CMS2_k127_4833855_26 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000009735 136.0
CMS2_k127_4833855_27 seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing K05808 - - 0.000000000000000000000000000000001698 136.0
CMS2_k127_4833855_28 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.00000000000000000000000000005618 129.0
CMS2_k127_4833855_29 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000005133 107.0
CMS2_k127_4833855_3 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 495.0
CMS2_k127_4833855_30 Alkylmercury lyase - - - 0.00000000000000000007224 93.0
CMS2_k127_4833855_31 ThiS family K03154 - - 0.0000000000000000003485 93.0
CMS2_k127_4833855_4 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 485.0
CMS2_k127_4833855_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 482.0
CMS2_k127_4833855_6 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 474.0
CMS2_k127_4833855_7 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 465.0
CMS2_k127_4833855_8 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 421.0
CMS2_k127_4833855_9 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 416.0
CMS2_k127_4848588_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 413.0
CMS2_k127_4848588_1 signal peptide peptidase K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 402.0
CMS2_k127_4848588_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 316.0
CMS2_k127_4848588_3 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000235 234.0
CMS2_k127_4848588_4 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000003456 214.0
CMS2_k127_4848588_5 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000001208 113.0
CMS2_k127_4848588_6 Psort location Cytoplasmic, score 8.96 K07040 - - 0.00000000000000000000001627 106.0
CMS2_k127_4871769_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001199 262.0
CMS2_k127_4871769_1 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000002168 156.0
CMS2_k127_4871769_2 UTRA K03710 - - 0.00000000000000000000000000000000000001571 149.0
CMS2_k127_4871769_3 GYD domain - - - 0.00014 47.0
CMS2_k127_4885617_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 4.474e-208 667.0
CMS2_k127_4885617_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 7.069e-195 616.0
CMS2_k127_4885617_10 Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 409.0
CMS2_k127_4885617_11 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 366.0
CMS2_k127_4885617_12 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006752 287.0
CMS2_k127_4885617_13 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000005227 256.0
CMS2_k127_4885617_14 FAD binding domain K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000001402 248.0
CMS2_k127_4885617_15 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000007546 259.0
CMS2_k127_4885617_16 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000001228 241.0
CMS2_k127_4885617_17 PFAM MGS domain protein K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000002288 221.0
CMS2_k127_4885617_18 Lactoylglutathione lyase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000001548 202.0
CMS2_k127_4885617_19 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000004706 192.0
CMS2_k127_4885617_2 aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 608.0
CMS2_k127_4885617_20 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000009975 131.0
CMS2_k127_4885617_21 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000002936 97.0
CMS2_k127_4885617_3 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 557.0
CMS2_k127_4885617_4 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 489.0
CMS2_k127_4885617_5 phosphate starvation-inducible protein PhoH K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 461.0
CMS2_k127_4885617_6 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009978 450.0
CMS2_k127_4885617_7 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 464.0
CMS2_k127_4885617_8 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 410.0
CMS2_k127_4885617_9 CBS domain containing protein K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 390.0
CMS2_k127_4927610_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 3.219e-235 751.0
CMS2_k127_4927610_1 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 288.0
CMS2_k127_4927610_2 Phasin protein - - - 0.0000000000000000000000000000000000000000000000002566 181.0
CMS2_k127_4927610_3 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000000000000000009769 173.0
CMS2_k127_5028038_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1598.0
CMS2_k127_5028038_1 FAD dependent oxidoreductase K06954 - - 5.971e-200 644.0
CMS2_k127_5028038_10 Protein of unknown function (DUF2878) - - - 0.00000000000000000000000000000000000000000000803 168.0
CMS2_k127_5028038_11 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000001827 154.0
CMS2_k127_5028038_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 500.0
CMS2_k127_5028038_3 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 415.0
CMS2_k127_5028038_4 Acyl-CoA dehydrogenase, C-terminal domain K22027 - 1.14.13.235 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 378.0
CMS2_k127_5028038_5 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 344.0
CMS2_k127_5028038_6 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 302.0
CMS2_k127_5028038_7 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007527 288.0
CMS2_k127_5028038_8 Outer Membrane Lipoprotein K03098 - - 0.00000000000000000000000000000000000000000000000000000000000000000003914 236.0
CMS2_k127_5028038_9 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000006593 190.0
CMS2_k127_5050940_0 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 5.401e-241 757.0
CMS2_k127_5050940_1 VWA domain containing CoxE-like protein K09989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 576.0
CMS2_k127_5050940_2 Cobalamin-independent synthase, Catalytic domain K00549,K22363 - 2.1.1.14,4.4.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 533.0
CMS2_k127_5050940_3 PFAM lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000003018 165.0
CMS2_k127_5050940_4 SnoaL-like domain - - - 0.00000000000000000000000007504 123.0
CMS2_k127_511067_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 1.7e-322 1009.0
CMS2_k127_511067_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 9.655e-269 831.0
CMS2_k127_511067_10 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000001584 239.0
CMS2_k127_511067_11 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000005378 205.0
CMS2_k127_511067_12 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000004338 173.0
CMS2_k127_511067_13 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000005208 128.0
CMS2_k127_511067_14 FixH K09926 - - 0.00000000000000000000000000000003663 130.0
CMS2_k127_511067_15 Protein of unknown function (DUF2892) - - - 0.000000000000000000001468 96.0
CMS2_k127_511067_16 Protein of unknown function (DUF2892) - - - 0.0000000000000000005672 90.0
CMS2_k127_511067_17 - - - - 0.000000000000000003374 93.0
CMS2_k127_511067_18 Cbb3-type cytochrome oxidase, subunit 3 K00407 - - 0.00000006238 55.0
CMS2_k127_511067_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 584.0
CMS2_k127_511067_3 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 542.0
CMS2_k127_511067_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 495.0
CMS2_k127_511067_5 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 363.0
CMS2_k127_511067_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 351.0
CMS2_k127_511067_7 cytochrome C oxidase K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 328.0
CMS2_k127_511067_8 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 285.0
CMS2_k127_511067_9 Ferritin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001205 278.0
CMS2_k127_5113000_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1215.0
CMS2_k127_5113000_1 dna topoisomerase III K03169 - 5.99.1.2 0.0 1125.0
CMS2_k127_5113000_10 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 381.0
CMS2_k127_5113000_11 PFAM Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 354.0
CMS2_k127_5113000_12 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 331.0
CMS2_k127_5113000_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000005947 237.0
CMS2_k127_5113000_14 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000000000000000001153 192.0
CMS2_k127_5113000_15 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000816 135.0
CMS2_k127_5113000_16 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000122 115.0
CMS2_k127_5113000_17 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000003094 68.0
CMS2_k127_5113000_18 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000003657 55.0
CMS2_k127_5113000_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 5.777e-291 905.0
CMS2_k127_5113000_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 601.0
CMS2_k127_5113000_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 568.0
CMS2_k127_5113000_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 497.0
CMS2_k127_5113000_6 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 491.0
CMS2_k127_5113000_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 437.0
CMS2_k127_5113000_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 418.0
CMS2_k127_5113000_9 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 394.0
CMS2_k127_5123424_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 452.0
CMS2_k127_5123424_1 cephalosporin hydroxylase - - - 0.0000000000000000000000000000000000000000000000001313 188.0
CMS2_k127_5129251_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 505.0
CMS2_k127_5129251_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 428.0
CMS2_k127_5129251_11 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000004748 80.0
CMS2_k127_5129251_12 Protein of unknown function (DUF1304) K08987 - - 0.00000000001147 67.0
CMS2_k127_5129251_13 - - - - 0.000000000038 70.0
CMS2_k127_5129251_14 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000005321 68.0
CMS2_k127_5129251_2 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 410.0
CMS2_k127_5129251_3 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 366.0
CMS2_k127_5129251_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 323.0
CMS2_k127_5129251_5 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000000142 193.0
CMS2_k127_5129251_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000001683 182.0
CMS2_k127_5129251_7 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000001815 159.0
CMS2_k127_5129251_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000009126 118.0
CMS2_k127_5129251_9 Protein of unknown function (DUF1304) K08987 - - 0.00000000000000000000000729 102.0
CMS2_k127_5260329_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 602.0
CMS2_k127_5260329_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 513.0
CMS2_k127_5260329_2 TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002677 248.0
CMS2_k127_5260329_3 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000000000000000000000000000000000001511 214.0
CMS2_k127_527071_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 542.0
CMS2_k127_527071_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 476.0
CMS2_k127_527071_10 Phospholipid-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 293.0
CMS2_k127_527071_11 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001027 279.0
CMS2_k127_527071_12 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000001197 211.0
CMS2_k127_527071_13 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000002918 136.0
CMS2_k127_527071_14 Endoribonuclease L-PSP - - - 0.0000000000000000000001573 112.0
CMS2_k127_527071_15 EamA-like transporter family - - - 0.0005671 49.0
CMS2_k127_527071_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 480.0
CMS2_k127_527071_3 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005761 434.0
CMS2_k127_527071_4 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 413.0
CMS2_k127_527071_5 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 432.0
CMS2_k127_527071_6 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 369.0
CMS2_k127_527071_7 7TM diverse intracellular signalling - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007488 361.0
CMS2_k127_527071_8 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 311.0
CMS2_k127_527071_9 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 312.0
CMS2_k127_5295019_0 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 2.237e-201 635.0
CMS2_k127_5295019_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 456.0
CMS2_k127_5341877_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1712.0
CMS2_k127_5341877_1 Activates fatty acids by binding to coenzyme A K00666,K01897 - 6.2.1.3 2.064e-216 689.0
CMS2_k127_5341877_10 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 441.0
CMS2_k127_5341877_11 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 383.0
CMS2_k127_5341877_12 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 370.0
CMS2_k127_5341877_13 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 347.0
CMS2_k127_5341877_14 KR domain K00076,K08081 - 1.1.1.159,1.1.1.206 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 311.0
CMS2_k127_5341877_15 Nucleoside-diphosphate-sugar epimerases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 307.0
CMS2_k127_5341877_16 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 298.0
CMS2_k127_5341877_17 phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002019 273.0
CMS2_k127_5341877_18 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000692 274.0
CMS2_k127_5341877_19 Enoyl-CoA hydratase carnithine racemase K01692,K11264 - 4.1.1.41,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000002696 237.0
CMS2_k127_5341877_2 D-galactarate dehydratase Altronate hydrolase K01685,K01708,K16846 - 4.2.1.42,4.2.1.7,4.4.1.24 1.761e-207 650.0
CMS2_k127_5341877_20 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000001496 227.0
CMS2_k127_5341877_21 Acetyltransferase K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000001681 220.0
CMS2_k127_5341877_22 Aconitase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000008592 222.0
CMS2_k127_5341877_23 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000006402 192.0
CMS2_k127_5341877_24 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000001788 176.0
CMS2_k127_5341877_25 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000008755 171.0
CMS2_k127_5341877_26 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000002603 156.0
CMS2_k127_5341877_27 ABC transporter transmembrane region K06148 - - 0.00000000000000000000000000000001592 132.0
CMS2_k127_5341877_28 membrane transporter protein K07090 - - 0.0000000000000000000000000000000336 136.0
CMS2_k127_5341877_29 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000002404 143.0
CMS2_k127_5341877_3 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 600.0
CMS2_k127_5341877_30 Protein conserved in bacteria K09796 - - 0.00000000000000000000000000004861 132.0
CMS2_k127_5341877_31 Extracellular ligand-binding receptor K01999 - - 0.0000000000006282 77.0
CMS2_k127_5341877_32 Extracellular ligand-binding receptor K01999 - - 0.000000002332 64.0
CMS2_k127_5341877_33 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 0.000000004109 68.0
CMS2_k127_5341877_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 595.0
CMS2_k127_5341877_5 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 508.0
CMS2_k127_5341877_6 PFAM L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 503.0
CMS2_k127_5341877_7 Phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 509.0
CMS2_k127_5341877_8 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 447.0
CMS2_k127_5341877_9 MltA-interacting MipA family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 438.0
CMS2_k127_5362776_0 4Fe-4S dicluster domain - - - 0.0 1200.0
CMS2_k127_5362776_1 transport system fused permease components - - - 0.0 1084.0
CMS2_k127_5362776_10 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 546.0
CMS2_k127_5362776_11 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 538.0
CMS2_k127_5362776_12 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 529.0
CMS2_k127_5362776_13 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 526.0
CMS2_k127_5362776_14 PFAM MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 541.0
CMS2_k127_5362776_15 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 498.0
CMS2_k127_5362776_16 Oligopeptide/dipeptide transporter, C-terminal region K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 485.0
CMS2_k127_5362776_17 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 459.0
CMS2_k127_5362776_18 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 451.0
CMS2_k127_5362776_19 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 435.0
CMS2_k127_5362776_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 4.808e-313 968.0
CMS2_k127_5362776_20 Binding-protein-dependent transport system inner membrane component K02033,K15585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 421.0
CMS2_k127_5362776_21 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 433.0
CMS2_k127_5362776_22 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 417.0
CMS2_k127_5362776_23 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 399.0
CMS2_k127_5362776_24 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 378.0
CMS2_k127_5362776_25 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 380.0
CMS2_k127_5362776_26 Histidine kinase K07641 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 380.0
CMS2_k127_5362776_27 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 366.0
CMS2_k127_5362776_28 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 333.0
CMS2_k127_5362776_29 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 318.0
CMS2_k127_5362776_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 8.698e-276 854.0
CMS2_k127_5362776_30 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 313.0
CMS2_k127_5362776_31 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 313.0
CMS2_k127_5362776_32 hydrolases of the HAD superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 299.0
CMS2_k127_5362776_33 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008842 273.0
CMS2_k127_5362776_34 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008029 276.0
CMS2_k127_5362776_35 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009887 269.0
CMS2_k127_5362776_36 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000002626 214.0
CMS2_k127_5362776_37 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000003499 186.0
CMS2_k127_5362776_38 PFAM Bacterial protein of - - - 0.000000000000000000000000000000000000000000000000435 181.0
CMS2_k127_5362776_39 Protein of unknown function, DUF - - - 0.000000000000000000000000000000000000000000000001855 175.0
CMS2_k127_5362776_4 Belongs to the IlvD Edd family - - - 1.543e-271 855.0
CMS2_k127_5362776_40 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000003043 181.0
CMS2_k127_5362776_41 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000003099 169.0
CMS2_k127_5362776_42 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000003543 186.0
CMS2_k127_5362776_43 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000002358 164.0
CMS2_k127_5362776_44 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000004681 161.0
CMS2_k127_5362776_45 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000002579 149.0
CMS2_k127_5362776_46 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000004449 149.0
CMS2_k127_5362776_47 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000006665 142.0
CMS2_k127_5362776_48 Thioredoxin-like domain - - - 0.00000000000000000000000000000000002653 143.0
CMS2_k127_5362776_49 - - - - 0.0000000000000000000000002129 109.0
CMS2_k127_5362776_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.103e-260 811.0
CMS2_k127_5362776_50 Sterol carrier protein - - - 0.00000000000000000000003718 104.0
CMS2_k127_5362776_51 ATP synthase I chain K02116 - - 0.0000000000000000003296 92.0
CMS2_k127_5362776_52 Histidine kinase - - - 0.000001127 62.0
CMS2_k127_5362776_53 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0001004 54.0
CMS2_k127_5362776_6 Protein of unknown function, DUF255 K06888 - - 2.475e-249 789.0
CMS2_k127_5362776_7 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 5.578e-195 620.0
CMS2_k127_5362776_8 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 609.0
CMS2_k127_5362776_9 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 563.0
CMS2_k127_5473926_0 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 364.0
CMS2_k127_5473926_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 298.0
CMS2_k127_549560_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 2.283e-226 724.0
CMS2_k127_549560_1 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 385.0
CMS2_k127_549560_2 Sel1-like repeats. - - - 0.00000000000001038 78.0
CMS2_k127_5553800_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.228e-290 902.0
CMS2_k127_5553800_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 609.0
CMS2_k127_5553800_10 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 451.0
CMS2_k127_5553800_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 417.0
CMS2_k127_5553800_12 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 403.0
CMS2_k127_5553800_13 HD domain K07814,K13815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 407.0
CMS2_k127_5553800_14 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 395.0
CMS2_k127_5553800_15 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 381.0
CMS2_k127_5553800_16 ATPase (AAA superfamily) K06923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 382.0
CMS2_k127_5553800_17 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 349.0
CMS2_k127_5553800_18 Pfam Enoyl-CoA hydratase isomerase K13816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 339.0
CMS2_k127_5553800_19 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 330.0
CMS2_k127_5553800_2 type II secretion system protein K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 603.0
CMS2_k127_5553800_20 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 293.0
CMS2_k127_5553800_21 Uracil DNA glycosylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009516 272.0
CMS2_k127_5553800_22 COG3000 Sterol desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001925 279.0
CMS2_k127_5553800_23 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001486 265.0
CMS2_k127_5553800_24 Iron-containing redox enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000003915 239.0
CMS2_k127_5553800_25 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000001847 236.0
CMS2_k127_5553800_26 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000002002 226.0
CMS2_k127_5553800_27 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000003175 222.0
CMS2_k127_5553800_28 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000001754 183.0
CMS2_k127_5553800_29 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000001065 177.0
CMS2_k127_5553800_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 587.0
CMS2_k127_5553800_30 preprotein translocase subunit YajC K03210 - - 0.00000000000000000000000000000000000000007592 153.0
CMS2_k127_5553800_31 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000005233 86.0
CMS2_k127_5553800_32 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0000000000002127 70.0
CMS2_k127_5553800_4 Histidine Phosphotransfer domain K10715 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 564.0
CMS2_k127_5553800_5 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 536.0
CMS2_k127_5553800_6 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 548.0
CMS2_k127_5553800_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 511.0
CMS2_k127_5553800_8 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 500.0
CMS2_k127_5553800_9 Mediates influx of magnesium ions K03284,K16074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 445.0
CMS2_k127_555477_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.231e-246 769.0
CMS2_k127_555477_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.869e-212 686.0
CMS2_k127_555477_10 colicin v production K03558 - - 0.00000000000000000000000000000004752 130.0
CMS2_k127_555477_11 Sporulation related domain K03749 - - 0.00000000000000000000952 99.0
CMS2_k127_555477_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 519.0
CMS2_k127_555477_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 455.0
CMS2_k127_555477_4 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 296.0
CMS2_k127_555477_5 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000567 244.0
CMS2_k127_555477_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000323 233.0
CMS2_k127_555477_7 PKHD-type hydroxylase K07336 - - 0.0000000000000000000000000000000000000000000000000000000001698 213.0
CMS2_k127_555477_8 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.0000000000000000000000000000000000000000000000000000000461 213.0
CMS2_k127_555477_9 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000002597 199.0
CMS2_k127_5567593_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1520.0
CMS2_k127_5567593_1 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.0 1126.0
CMS2_k127_5567593_10 MerT mercuric transport protein K08363 - - 0.000000000000000000001971 97.0
CMS2_k127_5567593_11 Transcriptional K19591 - - 0.00000000000000000005683 93.0
CMS2_k127_5567593_12 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0000000000000000000981 89.0
CMS2_k127_5567593_14 Belongs to the BI1 family K19416 - - 0.000000000000007081 75.0
CMS2_k127_5567593_15 Mercury scavenger that specifically binds to one mercury ion and which passes it to the mercuric reductase (MerA) via the MerT protein K08364 - - 0.000000001727 67.0
CMS2_k127_5567593_16 - - - - 0.0000003297 63.0
CMS2_k127_5567593_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 415.0
CMS2_k127_5567593_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 425.0
CMS2_k127_5567593_4 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001868 248.0
CMS2_k127_5567593_5 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000008879 220.0
CMS2_k127_5567593_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000002551 185.0
CMS2_k127_5567593_7 methyltransferase activity - - - 0.00000000000000000000000000000000000564 149.0
CMS2_k127_5567593_8 methyltransferase - - - 0.0000000000000000000000000000000003425 139.0
CMS2_k127_5567593_9 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000004121 107.0
CMS2_k127_564277_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01577,K01652,K03852 - 2.2.1.6,2.3.3.15,4.1.1.8 2.271e-313 967.0
CMS2_k127_564277_1 AcrB/AcrD/AcrF family - - - 3.182e-307 992.0
CMS2_k127_564277_10 - - - - 0.0000000000000000000000000000000000000000000000000000005326 201.0
CMS2_k127_564277_11 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000001 195.0
CMS2_k127_564277_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000001781 184.0
CMS2_k127_564277_13 lactoylglutathione lyase activity - - - 0.000000000000000000000001799 108.0
CMS2_k127_564277_14 2OG-Fe(II) oxygenase superfamily - - - 0.0000000000000000004316 90.0
CMS2_k127_564277_15 Rdx family K07401 - - 0.0000000002249 63.0
CMS2_k127_564277_2 FAD dependent oxidoreductase - - - 4.314e-245 764.0
CMS2_k127_564277_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652,K12673 - 2.2.1.6,2.5.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 590.0
CMS2_k127_564277_4 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 579.0
CMS2_k127_564277_5 Amidohydrolase K10220,K14333 - 4.1.1.46,4.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 516.0
CMS2_k127_564277_6 Glycosyltransferase family 9 (heptosyltransferase) K12982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 356.0
CMS2_k127_564277_7 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 340.0
CMS2_k127_564277_8 Domain of unknown function (DUF1932) - - - 0.0000000000000000000000000000000000000000000000000000000000000000008811 238.0
CMS2_k127_564277_9 4,5-dihydroxyphthalate decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000005743 220.0
CMS2_k127_5660714_0 LysR substrate binding domain K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 540.0
CMS2_k127_5660714_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0042802,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 313.0
CMS2_k127_5660714_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 291.0
CMS2_k127_5660714_3 Domain of unknown function (DUF202) - - - 0.0000000000000000000000000000000000000000000000000000000001752 204.0
CMS2_k127_5661382_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 510.0
CMS2_k127_5661382_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 509.0
CMS2_k127_5661382_2 Acyl-CoA dehydrogenase, C-terminal domain K16047 - 1.14.14.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 413.0
CMS2_k127_5661382_3 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 418.0
CMS2_k127_5661382_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002852 267.0
CMS2_k127_5661382_5 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000004629 250.0
CMS2_k127_5661382_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000007292 175.0
CMS2_k127_5661382_7 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000001251 122.0
CMS2_k127_5661382_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000002117 100.0
CMS2_k127_5663070_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.109e-209 684.0
CMS2_k127_5663070_1 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 585.0
CMS2_k127_5663070_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 532.0
CMS2_k127_5663070_3 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 469.0
CMS2_k127_5663070_4 enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006424 242.0
CMS2_k127_5663070_5 Universal stress protein family - - - 0.00000000000000000000000000000000000000002355 162.0
CMS2_k127_5664919_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1086.0
CMS2_k127_5664919_1 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 4.648e-235 735.0
CMS2_k127_5664919_10 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 401.0
CMS2_k127_5664919_11 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 396.0
CMS2_k127_5664919_12 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 379.0
CMS2_k127_5664919_13 RNA polymerase sigma K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 375.0
CMS2_k127_5664919_14 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 380.0
CMS2_k127_5664919_15 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 361.0
CMS2_k127_5664919_16 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 339.0
CMS2_k127_5664919_17 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008455 344.0
CMS2_k127_5664919_18 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 318.0
CMS2_k127_5664919_19 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 312.0
CMS2_k127_5664919_2 Bacterial protein of unknown function (DUF853) K06915 - - 1.137e-210 677.0
CMS2_k127_5664919_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 292.0
CMS2_k127_5664919_21 Cell division ATP-binding protein ftsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001967 275.0
CMS2_k127_5664919_22 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000288 257.0
CMS2_k127_5664919_23 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000295 249.0
CMS2_k127_5664919_24 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000001919 243.0
CMS2_k127_5664919_25 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000002095 236.0
CMS2_k127_5664919_26 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000007044 231.0
CMS2_k127_5664919_27 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000004734 234.0
CMS2_k127_5664919_28 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000265 250.0
CMS2_k127_5664919_29 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000002046 226.0
CMS2_k127_5664919_3 Belongs to the aldehyde dehydrogenase family K00141 - 1.2.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 594.0
CMS2_k127_5664919_30 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000002605 188.0
CMS2_k127_5664919_31 signal sequence binding - - - 0.000000000000000000000000000000000000000008776 162.0
CMS2_k127_5664919_32 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000002442 160.0
CMS2_k127_5664919_33 Outer membrane lipoprotein LolB - - - 0.0000000000000000000000000002318 133.0
CMS2_k127_5664919_34 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000008597 128.0
CMS2_k127_5664919_35 MerR HTH family regulatory protein K18997 - - 0.00000000000000005312 83.0
CMS2_k127_5664919_36 OmpA family - - - 0.00000000000001841 81.0
CMS2_k127_5664919_37 Protein of unknown function (DUF2909) - - - 0.000000001255 63.0
CMS2_k127_5664919_38 - - - - 0.0002962 43.0
CMS2_k127_5664919_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 555.0
CMS2_k127_5664919_5 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 518.0
CMS2_k127_5664919_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 501.0
CMS2_k127_5664919_7 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 492.0
CMS2_k127_5664919_8 heat shock protein DnaJ K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 437.0
CMS2_k127_5664919_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 410.0
CMS2_k127_5717690_0 TonB-dependent Receptor Plug Domain K02014 - - 3.86e-198 644.0
CMS2_k127_5717690_1 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007625 586.0
CMS2_k127_5717690_10 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007774 282.0
CMS2_k127_5717690_11 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000003776 218.0
CMS2_k127_5717690_12 Glycosyltransferase family 17 K00737 - 2.4.1.144 0.0000000000000000000000000001784 132.0
CMS2_k127_5717690_13 cytochrome - - - 0.000000000000009979 83.0
CMS2_k127_5717690_2 dehydratase K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 560.0
CMS2_k127_5717690_3 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 507.0
CMS2_k127_5717690_4 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 418.0
CMS2_k127_5717690_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 400.0
CMS2_k127_5717690_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 323.0
CMS2_k127_5717690_7 Ketopantoate reductase K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 309.0
CMS2_k127_5717690_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 303.0
CMS2_k127_5717690_9 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002709 283.0
CMS2_k127_5757482_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1386.0
CMS2_k127_5757482_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 8.733e-240 749.0
CMS2_k127_5757482_10 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000002429 136.0
CMS2_k127_5757482_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000001141 121.0
CMS2_k127_5757482_12 Protein of unknown function (DUF1161) - - - 0.0000000000000001374 85.0
CMS2_k127_5757482_13 - - - - 0.000000001584 62.0
CMS2_k127_5757482_2 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 397.0
CMS2_k127_5757482_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 350.0
CMS2_k127_5757482_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 348.0
CMS2_k127_5757482_5 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004388 284.0
CMS2_k127_5757482_6 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000149 254.0
CMS2_k127_5757482_7 spore germination - GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:1901682,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000006902 232.0
CMS2_k127_5757482_8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000008227 217.0
CMS2_k127_5757482_9 transcriptional regulator K07734 - - 0.0000000000000000000000000000000000000000000000004599 182.0
CMS2_k127_5759108_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.229e-272 863.0
CMS2_k127_5759108_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 489.0
CMS2_k127_5759108_2 heptosyltransferase II K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 359.0
CMS2_k127_5759108_3 Protein of unknown function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 314.0
CMS2_k127_5759108_4 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000009649 190.0
CMS2_k127_5759108_5 SnoaL-like domain - - - 0.00000000000000000000000000002707 119.0
CMS2_k127_5759108_6 Transcriptional regulator - - - 0.000000000000000000000209 100.0
CMS2_k127_5759108_7 Zinc-finger domain - - - 0.000000000000000000004332 106.0
CMS2_k127_5794918_0 Fumarate reductase flavoprotein C-term - - - 1.298e-251 788.0
CMS2_k127_5794918_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.456e-211 662.0
CMS2_k127_5794918_10 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 329.0
CMS2_k127_5794918_11 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000005479 243.0
CMS2_k127_5794918_12 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000003548 197.0
CMS2_k127_5794918_13 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000000000000000002834 139.0
CMS2_k127_5794918_14 Preprotein translocase subunit SecG K03075 - - 0.00000000000000000000000000001688 121.0
CMS2_k127_5794918_15 Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane K00246 - - 0.0000000000000000000000004829 116.0
CMS2_k127_5794918_16 Fumarate reductase subunit D - - - 0.00000000000000007088 89.0
CMS2_k127_5794918_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.014e-197 631.0
CMS2_k127_5794918_3 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 518.0
CMS2_k127_5794918_4 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 478.0
CMS2_k127_5794918_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 477.0
CMS2_k127_5794918_6 phosphate transport system K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 488.0
CMS2_k127_5794918_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 447.0
CMS2_k127_5794918_8 dihydropteroate synthase K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 328.0
CMS2_k127_5794918_9 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 314.0
CMS2_k127_5855236_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.471e-280 880.0
CMS2_k127_5855236_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.786e-209 658.0
CMS2_k127_5855236_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000002463 228.0
CMS2_k127_5855236_11 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000001825 193.0
CMS2_k127_5855236_12 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000001704 188.0
CMS2_k127_5855236_13 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.000000000000000000000000000000000000000000000000001036 184.0
CMS2_k127_5855236_14 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000007614 188.0
CMS2_k127_5855236_15 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.000000000000000000000000000000000000000000000002605 177.0
CMS2_k127_5855236_16 Protein of unknown function, DUF481 K07283 - - 0.0000000000000000000000000000000005218 144.0
CMS2_k127_5855236_17 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000002264 102.0
CMS2_k127_5855236_18 Iron-sulphur cluster assembly - - - 0.00000000000000000000321 110.0
CMS2_k127_5855236_19 Transglutaminase/protease-like homologues - - - 0.0000000004683 62.0
CMS2_k127_5855236_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007669 581.0
CMS2_k127_5855236_20 ubiE/COQ5 methyltransferase family - - - 0.0000004819 59.0
CMS2_k127_5855236_3 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 365.0
CMS2_k127_5855236_4 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 340.0
CMS2_k127_5855236_5 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 292.0
CMS2_k127_5855236_6 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000007906 263.0
CMS2_k127_5855236_7 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007317 251.0
CMS2_k127_5855236_8 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000009778 235.0
CMS2_k127_5855236_9 Rrf2 family transcriptional regulator, iron-sulfur cluster assembly K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000001057 231.0
CMS2_k127_5892_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 3.514e-205 646.0
CMS2_k127_5892_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 3.577e-205 653.0
CMS2_k127_5892_10 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001714 281.0
CMS2_k127_5892_11 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003591 277.0
CMS2_k127_5892_12 synthesis repressor, PhaR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004646 254.0
CMS2_k127_5892_13 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000009317 231.0
CMS2_k127_5892_14 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000007108 220.0
CMS2_k127_5892_15 - - - - 0.0000000000000000000000000000000000000000000000000000000953 206.0
CMS2_k127_5892_16 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000001699 194.0
CMS2_k127_5892_17 Glycine zipper 2TM domain - - - 0.000000000000000001296 87.0
CMS2_k127_5892_18 PFAM 17 kDa surface antigen - - - 0.0003797 46.0
CMS2_k127_5892_2 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 3.523e-200 647.0
CMS2_k127_5892_3 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009374 607.0
CMS2_k127_5892_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 529.0
CMS2_k127_5892_5 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 542.0
CMS2_k127_5892_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 394.0
CMS2_k127_5892_7 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 330.0
CMS2_k127_5892_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 325.0
CMS2_k127_5892_9 Zinc iron permease K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 298.0
CMS2_k127_5928926_0 SNARE associated Golgi protein - - - 0.0 1032.0
CMS2_k127_5928926_1 Tripartite tricarboxylate transporter TctA family - - - 6.683e-221 695.0
CMS2_k127_5928926_10 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000000003754 197.0
CMS2_k127_5928926_11 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000003535 188.0
CMS2_k127_5928926_12 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000008701 173.0
CMS2_k127_5928926_13 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000006782 139.0
CMS2_k127_5928926_14 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000006283 134.0
CMS2_k127_5928926_15 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000007318 132.0
CMS2_k127_5928926_16 4Fe-4S binding domain - - - 0.000000000000000000000000000002352 129.0
CMS2_k127_5928926_17 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000195 89.0
CMS2_k127_5928926_2 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 310.0
CMS2_k127_5928926_3 haloacid dehalogenase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 308.0
CMS2_k127_5928926_4 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001346 280.0
CMS2_k127_5928926_5 Dolichyl-phosphate-mannose-protein mannosyltransferase K00786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003806 272.0
CMS2_k127_5928926_6 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000002021 241.0
CMS2_k127_5928926_7 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000008494 224.0
CMS2_k127_5928926_8 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000002343 215.0
CMS2_k127_5928926_9 glycosyl transferase family 8 - - - 0.0000000000000000000000000000000000000000000000000000004919 201.0
CMS2_k127_5972949_0 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 311.0
CMS2_k127_5972949_1 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000165 229.0
CMS2_k127_5972949_2 - - - - 0.00000000000000000000001785 115.0
CMS2_k127_5972949_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000001451 57.0
CMS2_k127_5984948_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 428.0
CMS2_k127_5984948_1 PFAM ATP-binding region, ATPase-like histidine kinase A-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 363.0
CMS2_k127_5984948_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 334.0
CMS2_k127_5984948_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000001344 234.0
CMS2_k127_5984948_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000001411 169.0
CMS2_k127_6064856_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1373.0
CMS2_k127_6064856_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.763e-236 741.0
CMS2_k127_6064856_10 - - - - 0.00000000000000000000000000000001402 128.0
CMS2_k127_6064856_11 Adenylylsulfate kinase K00860 - 2.7.1.25 0.00000000000000000000000000001756 132.0
CMS2_k127_6064856_12 PFAM Cold-shock protein, DNA-binding - - - 0.00000000000000000000000001606 113.0
CMS2_k127_6064856_13 Host attachment protein - - - 0.00000000000000000000000002412 125.0
CMS2_k127_6064856_14 dksA traR - - - 0.0000000000000000000004226 100.0
CMS2_k127_6064856_15 PFAM PspC domain K03973 - - 0.00000000000000002647 87.0
CMS2_k127_6064856_16 COGs COG1196 Chromosome segregation ATPase - - - 0.000000000001864 76.0
CMS2_k127_6064856_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000003988 61.0
CMS2_k127_6064856_19 Phasin protein - - - 0.00001065 52.0
CMS2_k127_6064856_2 Belongs to the TPP enzyme family K01576 - 4.1.1.7 7.404e-200 638.0
CMS2_k127_6064856_3 DNA polymerase X family K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 616.0
CMS2_k127_6064856_4 PFAM Glycoside hydrolase family 65, central catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 577.0
CMS2_k127_6064856_5 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 522.0
CMS2_k127_6064856_6 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 512.0
CMS2_k127_6064856_7 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 376.0
CMS2_k127_6064856_8 Type ii and iii secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004443 274.0
CMS2_k127_6064856_9 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001535 246.0
CMS2_k127_6093009_0 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 3.075e-196 623.0
CMS2_k127_6093009_1 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 437.0
CMS2_k127_6093009_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 418.0
CMS2_k127_6093009_3 membrane-bound metal-dependent K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 319.0
CMS2_k127_6093009_4 Protein of unknown function (DUF3750) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001903 296.0
CMS2_k127_6093009_5 MarC family integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000007586 229.0
CMS2_k127_6093009_6 alginic acid biosynthetic process K12287 - - 0.000000000000000000000000000000000000000000000000000000000000016 246.0
CMS2_k127_6093009_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000002421 214.0
CMS2_k127_6093009_8 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000004646 219.0
CMS2_k127_6093009_9 OmpA-like transmembrane domain - - - 0.0000000004688 68.0
CMS2_k127_6096343_0 Domain of unknown function (DUF3362) - - - 0.0 1419.0
CMS2_k127_6096343_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.883e-255 795.0
CMS2_k127_6096343_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 333.0
CMS2_k127_6096343_3 GDSL-like Lipase/Acylhydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 322.0
CMS2_k127_6096343_4 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 308.0
CMS2_k127_6096343_5 FKBP-type peptidyl-prolyl cis-trans isomerase K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000005965 209.0
CMS2_k127_6125605_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000849 486.0
CMS2_k127_6125605_1 Preprotein translocase subunit TatD K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002226 298.0
CMS2_k127_6125605_2 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000275 210.0
CMS2_k127_6128363_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 570.0
CMS2_k127_6128363_1 ERAP1-like C-terminal domain K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 594.0
CMS2_k127_6128363_10 CBS domain - - - 0.000000000000000000000000000000000000000000000004346 176.0
CMS2_k127_6128363_11 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000009601 139.0
CMS2_k127_6128363_12 Resistance to Hg(2 ) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0) K00520,K21739 - 1.16.1.1 0.000000000000000000000000000000000001338 145.0
CMS2_k127_6128363_13 protein conserved in bacteria K09937 - - 0.0000000000000000005584 87.0
CMS2_k127_6128363_14 Acetyltransferase (GNAT) domain - - - 0.00000003408 57.0
CMS2_k127_6128363_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 558.0
CMS2_k127_6128363_3 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 501.0
CMS2_k127_6128363_4 Amidohydrolase K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 483.0
CMS2_k127_6128363_5 Divalent cation transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 468.0
CMS2_k127_6128363_6 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 427.0
CMS2_k127_6128363_7 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006824 397.0
CMS2_k127_6128363_8 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 404.0
CMS2_k127_6128363_9 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 384.0
CMS2_k127_6132997_0 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 471.0
CMS2_k127_6132997_1 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 432.0
CMS2_k127_6132997_2 GIY-YIG catalytic domain - - - 0.00000000000000000000000007414 107.0
CMS2_k127_6134790_0 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000001675 243.0
CMS2_k127_6134790_1 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000588 236.0
CMS2_k127_6134790_2 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000009494 166.0
CMS2_k127_6134790_3 Acetamidase/Formamidase family - - - 0.0000000000000000006072 93.0
CMS2_k127_6160862_0 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000001261 214.0
CMS2_k127_6160862_1 Alanine acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000005154 205.0
CMS2_k127_6160862_2 - - - - 0.00000000000000000000000000000000000001128 153.0
CMS2_k127_6160862_3 PFAM transglutaminase domain protein - - - 0.00000000001257 78.0
CMS2_k127_6169911_0 Periplasmic binding protein K01999 - - 4.526e-199 628.0
CMS2_k127_6169911_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 327.0
CMS2_k127_6169911_2 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000007992 229.0
CMS2_k127_6169911_3 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000001696 222.0
CMS2_k127_6176677_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 612.0
CMS2_k127_6176677_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 574.0
CMS2_k127_6176677_10 beta-keto acid cleavage enzyme - - - 0.0004125 51.0
CMS2_k127_6176677_2 glycolate oxidase subunit GlcD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 409.0
CMS2_k127_6176677_3 Aminotransferase class I and II K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 396.0
CMS2_k127_6176677_4 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005043 270.0
CMS2_k127_6176677_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000001084 235.0
CMS2_k127_6176677_6 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.0000000000000000000000000000000000000000000000000001295 191.0
CMS2_k127_6176677_7 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000000000009288 182.0
CMS2_k127_6176677_8 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000000000000000000000000000000299 180.0
CMS2_k127_6176677_9 Thioredoxin - - - 0.000000001123 68.0
CMS2_k127_6218505_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 2447.0
CMS2_k127_6218505_1 TspO/MBR family K05770 - - 0.0000000000000000001845 90.0
CMS2_k127_6220067_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1364.0
CMS2_k127_6220067_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 1.176e-260 816.0
CMS2_k127_6220067_10 Succinate dehydrogenase hydrophobic membrane anchor protein K00242 - - 0.0000000000000000000000000000000004989 140.0
CMS2_k127_6220067_11 TonB-dependent receptor plug K02014 - - 0.0000000000000000000000000003396 117.0
CMS2_k127_6220067_12 Flavinator of succinate dehydrogenase K09159 - - 0.000000000284 70.0
CMS2_k127_6220067_13 Protein of unknown function (DUF3460) - - - 0.00002718 56.0
CMS2_k127_6220067_2 MmgE/PrpD family K01720 - 4.2.1.79 6.561e-245 766.0
CMS2_k127_6220067_3 E1 component K00164 - 1.2.4.2 1.894e-230 724.0
CMS2_k127_6220067_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.58e-229 716.0
CMS2_k127_6220067_5 also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity K01659 - 2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 591.0
CMS2_k127_6220067_6 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 479.0
CMS2_k127_6220067_7 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 442.0
CMS2_k127_6220067_8 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 421.0
CMS2_k127_6220067_9 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.000000000000000000000000000000000003569 144.0
CMS2_k127_6223459_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1230.0
CMS2_k127_6223459_1 DNA helicase K03657 - 3.6.4.12 3.514e-298 930.0
CMS2_k127_6223459_10 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000003 233.0
CMS2_k127_6223459_11 Bacterial transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000001164 222.0
CMS2_k127_6223459_12 Domain of unknown function (DUF4398) - - - 0.0000000000000000000000000000000000000000000000000000008012 204.0
CMS2_k127_6223459_13 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.0000000000000000000000000000000000000000000000000304 196.0
CMS2_k127_6223459_14 - - - - 0.000000000000000000000000000000000000000000000003327 180.0
CMS2_k127_6223459_15 epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000001742 173.0
CMS2_k127_6223459_16 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000004066 168.0
CMS2_k127_6223459_17 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000009739 156.0
CMS2_k127_6223459_18 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000000000003685 153.0
CMS2_k127_6223459_19 membrane - - - 0.0000000000000000000000000000005454 128.0
CMS2_k127_6223459_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 2.866e-232 727.0
CMS2_k127_6223459_20 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000001509 107.0
CMS2_k127_6223459_21 Domain of unknown function (DUF4398) - - - 0.0000000008023 65.0
CMS2_k127_6223459_3 ribonuclease, Rne Rng family K08301 - - 2.841e-227 716.0
CMS2_k127_6223459_4 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 1.734e-214 686.0
CMS2_k127_6223459_5 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 597.0
CMS2_k127_6223459_6 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 565.0
CMS2_k127_6223459_7 Soluble lytic murein transglycosylase L domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 494.0
CMS2_k127_6223459_8 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 316.0
CMS2_k127_6223459_9 Sporulation related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005239 254.0
CMS2_k127_6231117_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1442.0
CMS2_k127_6231117_1 Malic enzyme K00029 - 1.1.1.40 0.0 1071.0
CMS2_k127_6231117_10 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 475.0
CMS2_k127_6231117_11 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 436.0
CMS2_k127_6231117_12 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 430.0
CMS2_k127_6231117_13 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 426.0
CMS2_k127_6231117_14 PFAM aminotransferase, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 418.0
CMS2_k127_6231117_15 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 438.0
CMS2_k127_6231117_16 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 417.0
CMS2_k127_6231117_17 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 404.0
CMS2_k127_6231117_18 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 368.0
CMS2_k127_6231117_19 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 389.0
CMS2_k127_6231117_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.167e-259 811.0
CMS2_k127_6231117_20 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 354.0
CMS2_k127_6231117_21 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 315.0
CMS2_k127_6231117_22 Transglycosylase SLT domain K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005735 307.0
CMS2_k127_6231117_23 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009635 282.0
CMS2_k127_6231117_24 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002434 272.0
CMS2_k127_6231117_25 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001816 289.0
CMS2_k127_6231117_26 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002077 259.0
CMS2_k127_6231117_27 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000001077 258.0
CMS2_k127_6231117_28 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001436 251.0
CMS2_k127_6231117_29 Lysin motif K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000002102 252.0
CMS2_k127_6231117_3 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 1.659e-206 649.0
CMS2_k127_6231117_30 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000000000000000000000000000000003668 250.0
CMS2_k127_6231117_31 Negative regulator of K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000002751 228.0
CMS2_k127_6231117_32 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000007274 222.0
CMS2_k127_6231117_33 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.000000000000000000000000000000000000000000000000000009554 210.0
CMS2_k127_6231117_34 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000003729 157.0
CMS2_k127_6231117_35 diol metabolic process K01724 - 4.2.1.96 0.000000000000000000000000000000000000003681 160.0
CMS2_k127_6231117_36 CNP1-like family - - - 0.000000000000000000000000000000000000007047 156.0
CMS2_k127_6231117_37 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000000008272 149.0
CMS2_k127_6231117_38 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000626 126.0
CMS2_k127_6231117_39 - - - - 0.00000000000000000000000000867 113.0
CMS2_k127_6231117_4 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 603.0
CMS2_k127_6231117_40 Ribosomal protein L31 K02909 - - 0.00000000000000000000000001377 111.0
CMS2_k127_6231117_41 Putative prokaryotic signal transducing protein - - - 0.0000000000000000000001027 103.0
CMS2_k127_6231117_42 - - - - 0.000000000000000009443 97.0
CMS2_k127_6231117_44 Glcg protein - - - 0.000000000002317 70.0
CMS2_k127_6231117_45 - K06950 - - 0.00000000000269 69.0
CMS2_k127_6231117_46 Protein of unknown function (DUF2442) - - - 0.00000004184 66.0
CMS2_k127_6231117_47 Histone H1-like nucleoprotein HC2 K11275 - - 0.0001938 48.0
CMS2_k127_6231117_48 - - - - 0.0009133 46.0
CMS2_k127_6231117_5 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 571.0
CMS2_k127_6231117_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 516.0
CMS2_k127_6231117_7 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 541.0
CMS2_k127_6231117_8 PFAM Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 504.0
CMS2_k127_6231117_9 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 476.0
CMS2_k127_6248043_0 PFAM Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 566.0
CMS2_k127_6248043_1 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004512 586.0
CMS2_k127_6248043_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 361.0
CMS2_k127_6248043_11 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 352.0
CMS2_k127_6248043_12 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 345.0
CMS2_k127_6248043_13 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 290.0
CMS2_k127_6248043_14 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000002045 273.0
CMS2_k127_6248043_15 Alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000502 232.0
CMS2_k127_6248043_16 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000000000000000000000000000000000000002952 190.0
CMS2_k127_6248043_17 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000002379 155.0
CMS2_k127_6248043_18 COG0457 FOG TPR repeat - - - 0.00000000000000000000000002143 117.0
CMS2_k127_6248043_19 - - - - 0.000000000000000000006824 107.0
CMS2_k127_6248043_2 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 534.0
CMS2_k127_6248043_20 Domain of unknown function (DUF1992) - - - 0.00000000006405 64.0
CMS2_k127_6248043_3 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 444.0
CMS2_k127_6248043_4 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 424.0
CMS2_k127_6248043_5 Putative nucleotide-binding of sugar-metabolising enzyme K21948 - 2.7.1.217 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 394.0
CMS2_k127_6248043_6 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 377.0
CMS2_k127_6248043_7 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 396.0
CMS2_k127_6248043_8 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 374.0
CMS2_k127_6248043_9 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 356.0
CMS2_k127_6254827_0 DNA polymerase K02337 - 2.7.7.7 0.0 1375.0
CMS2_k127_6254827_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.399e-280 877.0
CMS2_k127_6254827_10 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000004287 158.0
CMS2_k127_6254827_11 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000004361 104.0
CMS2_k127_6254827_12 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000445 93.0
CMS2_k127_6254827_13 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000006673 91.0
CMS2_k127_6254827_14 FAD binding domain K09828 - 1.3.1.72 0.000000001009 70.0
CMS2_k127_6254827_2 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 483.0
CMS2_k127_6254827_3 permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 374.0
CMS2_k127_6254827_4 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 351.0
CMS2_k127_6254827_5 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 308.0
CMS2_k127_6254827_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003337 262.0
CMS2_k127_6254827_7 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006355 267.0
CMS2_k127_6254827_8 Helix-turn-helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002179 216.0
CMS2_k127_6254827_9 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000000000000000002811 182.0
CMS2_k127_6305946_0 Mandelate Racemase Muconate Lactonizing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009435 500.0
CMS2_k127_6305946_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 289.0
CMS2_k127_6305946_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000703 42.0
CMS2_k127_6338552_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 589.0
CMS2_k127_6338552_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 513.0
CMS2_k127_6338552_10 - - - - 0.000000000000000000000000000000000003175 144.0
CMS2_k127_6338552_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 512.0
CMS2_k127_6338552_3 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 503.0
CMS2_k127_6338552_4 oxidoreductase FAD NAD(P)-binding domain protein K00523,K18248 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 467.0
CMS2_k127_6338552_5 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 401.0
CMS2_k127_6338552_6 branched-chain amino acid K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 349.0
CMS2_k127_6338552_7 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007618 290.0
CMS2_k127_6338552_8 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000000000006749 210.0
CMS2_k127_6338552_9 protein involved in tolerance to divalent cations K03926 - - 0.000000000000000000000000000000000002051 148.0
CMS2_k127_6346785_0 TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA K03694 - - 0.0 1188.0
CMS2_k127_6346785_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1160.0
CMS2_k127_6346785_10 COG0765 ABC-type amino acid transport system, permease component K09971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 499.0
CMS2_k127_6346785_11 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 475.0
CMS2_k127_6346785_12 dehydrogenase K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 447.0
CMS2_k127_6346785_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 450.0
CMS2_k127_6346785_14 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 449.0
CMS2_k127_6346785_15 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004262 434.0
CMS2_k127_6346785_16 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 446.0
CMS2_k127_6346785_17 acid transport K09972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008928 396.0
CMS2_k127_6346785_18 amino acid ABC transporter K09970 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 343.0
CMS2_k127_6346785_19 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 335.0
CMS2_k127_6346785_2 Amidohydrolase family - - - 1.511e-272 846.0
CMS2_k127_6346785_20 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 328.0
CMS2_k127_6346785_21 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 344.0
CMS2_k127_6346785_22 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 308.0
CMS2_k127_6346785_23 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 299.0
CMS2_k127_6346785_24 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 289.0
CMS2_k127_6346785_25 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 293.0
CMS2_k127_6346785_26 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000006389 256.0
CMS2_k127_6346785_27 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000866 262.0
CMS2_k127_6346785_28 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000029 249.0
CMS2_k127_6346785_29 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001577 254.0
CMS2_k127_6346785_3 Isocitrate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 2.829e-228 729.0
CMS2_k127_6346785_30 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000003754 263.0
CMS2_k127_6346785_31 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000002959 219.0
CMS2_k127_6346785_32 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000001496 194.0
CMS2_k127_6346785_33 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000001818 203.0
CMS2_k127_6346785_34 Phasin protein - - - 0.0000000000000000000000000000000000000000000000000001701 192.0
CMS2_k127_6346785_35 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000007698 182.0
CMS2_k127_6346785_36 TraB family K09973 - - 0.000000000000000000000000000000000000000000000024 191.0
CMS2_k127_6346785_37 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000004084 171.0
CMS2_k127_6346785_38 Protein of unknown function (DUF1643) - - - 0.000000000000000000000000000000000000000000006991 183.0
CMS2_k127_6346785_39 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000147 163.0
CMS2_k127_6346785_4 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.602e-212 683.0
CMS2_k127_6346785_40 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000002302 163.0
CMS2_k127_6346785_41 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000000000000000001095 148.0
CMS2_k127_6346785_42 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000002583 135.0
CMS2_k127_6346785_43 Cold shock K03704 - - 0.000000000000000000000000000000003953 130.0
CMS2_k127_6346785_44 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000003313 121.0
CMS2_k127_6346785_45 - - - - 0.0000000000000000000000000002914 121.0
CMS2_k127_6346785_46 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000005473 96.0
CMS2_k127_6346785_47 cytochrome - - - 0.00000000000000000009725 94.0
CMS2_k127_6346785_48 Protein of unknown function (DUF3108) - - - 0.00000000000345 75.0
CMS2_k127_6346785_49 - - - - 0.0005888 46.0
CMS2_k127_6346785_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 2.419e-203 640.0
CMS2_k127_6346785_6 Tripartite ATP-independent periplasmic transporter, DctM component - - - 5.893e-203 640.0
CMS2_k127_6346785_7 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 5.196e-196 625.0
CMS2_k127_6346785_8 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 550.0
CMS2_k127_6346785_9 sulfide dehydrogenase K05301 - 1.8.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 503.0
CMS2_k127_6350105_0 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 366.0
CMS2_k127_6350105_1 Nitrile hydratase K01721,K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000008301 218.0
CMS2_k127_6350105_2 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000001554 209.0
CMS2_k127_6350105_3 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.0000000000000000000000000000000000000004609 151.0
CMS2_k127_6350105_4 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.00000000000000000000002867 102.0
CMS2_k127_6380234_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 484.0
CMS2_k127_6380234_1 Cellulose synthase K00694,K20541 - 2.4.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 445.0
CMS2_k127_6380234_10 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000000006341 152.0
CMS2_k127_6380234_11 Sulfurtransferase TusA K04085 - - 0.00000000000000000000000000000001985 126.0
CMS2_k127_6380234_12 - - - - 0.0000000000000000000000000002806 117.0
CMS2_k127_6380234_13 - - - - 0.000000000000000000000000001885 121.0
CMS2_k127_6380234_14 Sulfurtransferase TusA - - - 0.0000000000000000000001779 98.0
CMS2_k127_6380234_15 - - - - 0.000000000000000004221 86.0
CMS2_k127_6380234_16 6-phosphogluconolactonase activity - - - 0.000000000000001986 85.0
CMS2_k127_6380234_17 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000004677 75.0
CMS2_k127_6380234_18 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.000000002238 69.0
CMS2_k127_6380234_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 332.0
CMS2_k127_6380234_20 response regulator - - - 0.00000009861 63.0
CMS2_k127_6380234_21 zinc-ribbon domain - - - 0.0000002296 59.0
CMS2_k127_6380234_22 peptidyl-tyrosine sulfation - - - 0.0003492 51.0
CMS2_k127_6380234_3 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002507 265.0
CMS2_k127_6380234_4 PKHD-type hydroxylase K07336 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002191 253.0
CMS2_k127_6380234_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003332 251.0
CMS2_k127_6380234_6 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005003 244.0
CMS2_k127_6380234_7 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.00000000000000000000000000000000000000000000000000001991 199.0
CMS2_k127_6380234_8 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000006604 176.0
CMS2_k127_6380234_9 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000000000000007908 163.0
CMS2_k127_6386402_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 334.0
CMS2_k127_6386402_1 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000269 277.0
CMS2_k127_6386402_10 Copper binding periplasmic protein CusF - - - 0.0000000000000000000001362 101.0
CMS2_k127_6386402_11 Short C-terminal domain K08982 - - 0.000000000000006313 78.0
CMS2_k127_6386402_12 Protein of unknown function (DUF1573) - - - 0.00003632 53.0
CMS2_k127_6386402_2 periplasmic protein thiol disulfide K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000003666 232.0
CMS2_k127_6386402_3 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000376 215.0
CMS2_k127_6386402_4 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000000000000000000000000000000001067 178.0
CMS2_k127_6386402_5 - - - - 0.00000000000000000000000000000000000000000171 160.0
CMS2_k127_6386402_6 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.000000000000000000000000000000000000238 150.0
CMS2_k127_6386402_7 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000002888 142.0
CMS2_k127_6386402_8 - - - - 0.000000000000000000000000006335 117.0
CMS2_k127_6386402_9 ATP-independent chaperone mediated protein folding - - - 0.000000000000000000000002018 108.0
CMS2_k127_6389779_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 561.0
CMS2_k127_6389779_1 PFAM peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008746 389.0
CMS2_k127_6389779_10 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000000003517 170.0
CMS2_k127_6389779_11 - - - - 0.0000000000000000000000000000000000002566 145.0
CMS2_k127_6389779_12 Gram-negative porin - - - 0.000000000000000000000000000000003432 141.0
CMS2_k127_6389779_2 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 403.0
CMS2_k127_6389779_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 367.0
CMS2_k127_6389779_4 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000001179 244.0
CMS2_k127_6389779_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000005887 231.0
CMS2_k127_6389779_6 regulator of disulfide bond formation K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000006837 227.0
CMS2_k127_6389779_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000001345 215.0
CMS2_k127_6389779_8 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000003644 212.0
CMS2_k127_6389779_9 - - - - 0.00000000000000000000000000000000000000000000004713 179.0
CMS2_k127_6393249_0 Domain of unknown function (DUF4139) - - - 2.758e-195 621.0
CMS2_k127_6393249_1 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 593.0
CMS2_k127_6393249_10 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000000001192 205.0
CMS2_k127_6393249_11 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000008579 178.0
CMS2_k127_6393249_12 - - - - 0.000000000000000000000000000000000000000000000003 186.0
CMS2_k127_6393249_13 Ureidoglycolate lyase - - - 0.00000000000000000000000000000000000000000000000332 194.0
CMS2_k127_6393249_14 Hydantoinase B/oxoprolinase - - - 0.000000000000000000000000000000000000000000000008161 174.0
CMS2_k127_6393249_15 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000003686 133.0
CMS2_k127_6393249_16 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000048 132.0
CMS2_k127_6393249_17 LTXXQ motif family protein - - - 0.000000000000358 78.0
CMS2_k127_6393249_18 - - - - 0.000006659 57.0
CMS2_k127_6393249_2 Belongs to the glutamine synthetase family K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 571.0
CMS2_k127_6393249_3 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 497.0
CMS2_k127_6393249_4 L-seryl-tRNA selenium transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 459.0
CMS2_k127_6393249_5 Histidine kinase K05962 - 2.7.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 439.0
CMS2_k127_6393249_6 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 396.0
CMS2_k127_6393249_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 344.0
CMS2_k127_6393249_8 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006267 278.0
CMS2_k127_6393249_9 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000002917 230.0
CMS2_k127_6492128_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 509.0
CMS2_k127_6492128_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 502.0
CMS2_k127_6492128_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 338.0
CMS2_k127_6492128_3 - - - - 0.00000000000000000000000005671 112.0
CMS2_k127_6492128_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000002648 72.0
CMS2_k127_6507585_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1707.0
CMS2_k127_6507585_1 Histidine kinase-like ATPases K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 582.0
CMS2_k127_6507585_10 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000001011 236.0
CMS2_k127_6507585_11 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000008507 225.0
CMS2_k127_6507585_12 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000001221 212.0
CMS2_k127_6507585_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000007048 128.0
CMS2_k127_6507585_14 CRS1_YhbY K07574 - - 0.0000000000000000000001334 101.0
CMS2_k127_6507585_2 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 557.0
CMS2_k127_6507585_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 525.0
CMS2_k127_6507585_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 499.0
CMS2_k127_6507585_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 452.0
CMS2_k127_6507585_6 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 413.0
CMS2_k127_6507585_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 342.0
CMS2_k127_6507585_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 318.0
CMS2_k127_6507585_9 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 310.0
CMS2_k127_6524293_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.744e-260 816.0
CMS2_k127_6524293_1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002155 280.0
CMS2_k127_6524293_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000008161 221.0
CMS2_k127_6524293_3 PIN domain K07063 - - 0.000000000000000000000005181 106.0
CMS2_k127_6524293_4 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000003206 83.0
CMS2_k127_6536684_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2437.0
CMS2_k127_6536684_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 2.051e-317 991.0
CMS2_k127_6536684_2 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005059 530.0
CMS2_k127_6536684_3 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 511.0
CMS2_k127_6536684_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001399 259.0
CMS2_k127_6536684_5 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.00000006996 62.0
CMS2_k127_6576308_0 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 531.0
CMS2_k127_6576308_1 Benzoate membrane transport protein K05782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 490.0
CMS2_k127_6576308_10 Cupin domain - - - 0.000000000000000009766 86.0
CMS2_k127_6576308_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 387.0
CMS2_k127_6576308_3 thiamine-containing compound biosynthetic process K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 358.0
CMS2_k127_6576308_4 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 349.0
CMS2_k127_6576308_5 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 340.0
CMS2_k127_6576308_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000004077 219.0
CMS2_k127_6576308_7 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000000000000000002816 203.0
CMS2_k127_6576308_8 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000002174 190.0
CMS2_k127_6576308_9 Alkylmercury lyase - - - 0.000000000000000000000003115 104.0
CMS2_k127_65817_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 490.0
CMS2_k127_65817_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000008605 242.0
CMS2_k127_65817_2 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000001349 109.0
CMS2_k127_65817_3 Nitrile hydratase K01721,K20807 - 4.2.1.84 0.00000000000000000000001626 101.0
CMS2_k127_6604285_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 2.849e-243 763.0
CMS2_k127_6604285_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 7.852e-208 652.0
CMS2_k127_6604285_10 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 384.0
CMS2_k127_6604285_11 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 372.0
CMS2_k127_6604285_12 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 397.0
CMS2_k127_6604285_13 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 371.0
CMS2_k127_6604285_14 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 356.0
CMS2_k127_6604285_15 ATP-binding protein K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 356.0
CMS2_k127_6604285_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 335.0
CMS2_k127_6604285_17 Glutaredoxin K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005183 324.0
CMS2_k127_6604285_18 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 326.0
CMS2_k127_6604285_19 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 306.0
CMS2_k127_6604285_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 575.0
CMS2_k127_6604285_20 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 286.0
CMS2_k127_6604285_21 Cytochrome C1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003594 285.0
CMS2_k127_6604285_22 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000006408 259.0
CMS2_k127_6604285_23 ATPase activity, coupled to transmembrane movement of substances - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004653 251.0
CMS2_k127_6604285_24 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005558 256.0
CMS2_k127_6604285_25 VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000782 235.0
CMS2_k127_6604285_26 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000003651 218.0
CMS2_k127_6604285_27 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.0000000000000000000000000000000000000000000000000000001076 201.0
CMS2_k127_6604285_28 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000001987 203.0
CMS2_k127_6604285_29 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000007901 189.0
CMS2_k127_6604285_3 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 533.0
CMS2_k127_6604285_30 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000000000000000004415 177.0
CMS2_k127_6604285_31 Psort location Cytoplasmic, score K01523 - 3.6.1.31 0.00000000000000000000000000000000000004456 146.0
CMS2_k127_6604285_32 stringent starvation protein b K03600 - - 0.0000000000000000000000000000000000002687 153.0
CMS2_k127_6604285_33 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000155 115.0
CMS2_k127_6604285_34 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000001163 108.0
CMS2_k127_6604285_35 Belongs to the BolA IbaG family - - - 0.00000000000000000000002921 113.0
CMS2_k127_6604285_36 - - - - 0.0000000000000000007247 95.0
CMS2_k127_6604285_37 - - - - 0.00000000000000003729 93.0
CMS2_k127_6604285_38 STAS domain K07122 - - 0.0000000000001203 76.0
CMS2_k127_6604285_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 509.0
CMS2_k127_6604285_5 type II secretion system protein K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005003 487.0
CMS2_k127_6604285_6 Belongs to the peptidase S1C family K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 483.0
CMS2_k127_6604285_7 Type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 447.0
CMS2_k127_6604285_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 411.0
CMS2_k127_6604285_9 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 409.0
CMS2_k127_6612924_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 1.684e-264 854.0
CMS2_k127_6612924_1 4Fe-4S dicluster domain - - - 1.724e-262 814.0
CMS2_k127_6612924_2 reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 9.141e-200 627.0
CMS2_k127_6612924_3 reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 366.0
CMS2_k127_6612924_4 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 353.0
CMS2_k127_6612924_5 TIGRFAM sulfur relay protein TusD DsrE K07235 GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0019417,GO:0044237,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000527 223.0
CMS2_k127_6612924_6 DsrC like protein - - - 0.00000000000000000000000000000000000000000000000000000007958 198.0
CMS2_k127_6612924_7 Belongs to the DsrF TusC family K07236 - - 0.0000000000000000000000000000000000000000000000000005016 186.0
CMS2_k127_6612924_8 sulfur relay protein TusB DsrH K07237 - - 0.000000000000000000000000000000001634 138.0
CMS2_k127_6654132_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1814.0
CMS2_k127_6654132_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.029e-208 672.0
CMS2_k127_6654132_10 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000008157 237.0
CMS2_k127_6654132_11 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000008849 211.0
CMS2_k127_6654132_12 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000001412 163.0
CMS2_k127_6654132_13 protein conserved in bacteria K09780 - - 0.0000000000000000000000000008781 115.0
CMS2_k127_6654132_2 in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence K06020 GO:0003674,GO:0003824,GO:0005488,GO:0006417,GO:0006448,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0044877,GO:0045900,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 3.6.3.25 2.663e-204 677.0
CMS2_k127_6654132_3 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 567.0
CMS2_k127_6654132_4 Tripartite tricarboxylate transporter TctA family K07793 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 547.0
CMS2_k127_6654132_5 Glucose sorbosone K21430 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 539.0
CMS2_k127_6654132_6 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 499.0
CMS2_k127_6654132_7 serine protease K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 467.0
CMS2_k127_6654132_8 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 368.0
CMS2_k127_6654132_9 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 327.0
CMS2_k127_6660475_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002684 285.0
CMS2_k127_6661967_0 GTP-binding protein K06207 - - 1.642e-308 954.0
CMS2_k127_6661967_1 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000003066 285.0
CMS2_k127_6661967_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000015 268.0
CMS2_k127_6661967_3 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000001145 259.0
CMS2_k127_6661967_4 Predicted membrane protein (DUF2069) - - - 0.0000000000000000000000000000000331 138.0
CMS2_k127_6661967_5 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.00000000000000007318 83.0
CMS2_k127_6707531_0 extracellular solute-binding protein - - - 6.923e-284 887.0
CMS2_k127_6707531_1 PFAM AMP-dependent synthetase K01895 - 6.2.1.1 6.914e-246 779.0
CMS2_k127_6707531_10 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 364.0
CMS2_k127_6707531_11 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 334.0
CMS2_k127_6707531_12 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003278 289.0
CMS2_k127_6707531_13 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001252 272.0
CMS2_k127_6707531_14 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003163 260.0
CMS2_k127_6707531_15 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000001865 231.0
CMS2_k127_6707531_16 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000001158 170.0
CMS2_k127_6707531_17 - - - - 0.00000000000000008728 84.0
CMS2_k127_6707531_18 Phosphopantetheine attachment site K02078 - - 0.0000000001328 64.0
CMS2_k127_6707531_19 - - - - 0.0003245 49.0
CMS2_k127_6707531_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 4.118e-233 751.0
CMS2_k127_6707531_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 537.0
CMS2_k127_6707531_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 526.0
CMS2_k127_6707531_5 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008317 443.0
CMS2_k127_6707531_6 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 421.0
CMS2_k127_6707531_7 L-Asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 441.0
CMS2_k127_6707531_8 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 408.0
CMS2_k127_6707531_9 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 381.0
CMS2_k127_67149_0 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 349.0
CMS2_k127_67149_1 haloacid dehalogenase-like hydrolase K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000006315 255.0
CMS2_k127_67149_2 Conserved TM helix - - - 0.0001254 46.0
CMS2_k127_6730854_0 Methyltransferase - - - 1.117e-225 714.0
CMS2_k127_6730854_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 2.661e-202 639.0
CMS2_k127_6730854_10 Pyrimidine 5''-nucleotidase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001535 248.0
CMS2_k127_6730854_11 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000002505 242.0
CMS2_k127_6730854_12 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000001644 224.0
CMS2_k127_6730854_13 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000003292 225.0
CMS2_k127_6730854_14 Bacterial regulatory proteins, tetR family K05501 - - 0.000000000000000000000000000000000000000000000000000000000001459 214.0
CMS2_k127_6730854_15 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000003256 213.0
CMS2_k127_6730854_16 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000001261 192.0
CMS2_k127_6730854_17 Bacterial SH3 domain - - - 0.000000000000000000000000000000001147 136.0
CMS2_k127_6730854_18 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000003637 117.0
CMS2_k127_6730854_19 Rhodanese Homology Domain - - - 0.000000000000000000000000002201 129.0
CMS2_k127_6730854_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 621.0
CMS2_k127_6730854_20 Integral membrane protein (DUF2244) - - - 0.0000000000000000001381 96.0
CMS2_k127_6730854_3 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 444.0
CMS2_k127_6730854_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 437.0
CMS2_k127_6730854_5 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 390.0
CMS2_k127_6730854_6 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 372.0
CMS2_k127_6730854_7 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 312.0
CMS2_k127_6730854_8 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 316.0
CMS2_k127_6730854_9 peptidase, M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008507 274.0
CMS2_k127_6797475_0 histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 428.0
CMS2_k127_6797475_1 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 424.0
CMS2_k127_6797475_2 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 376.0
CMS2_k127_6797475_3 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 339.0
CMS2_k127_6797475_4 binding-protein-dependent transport systems inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 311.0
CMS2_k127_6797475_5 Binding-protein-dependent transport system inner membrane component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008322 282.0
CMS2_k127_6797475_6 GTP-binding protein TypA K06207 - - 0.0000000000000000000000002819 105.0
CMS2_k127_691588_0 AMP-binding enzyme C-terminal domain K12507 - - 2.733e-227 715.0
CMS2_k127_691588_1 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 615.0
CMS2_k127_691588_2 Belongs to the enoyl-CoA hydratase isomerase family. MenB subfamily K01661,K07536 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 445.0
CMS2_k127_691588_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001512 267.0
CMS2_k127_691588_4 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000006051 190.0
CMS2_k127_6941624_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1176.0
CMS2_k127_6941624_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1116.0
CMS2_k127_6941624_10 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009582 383.0
CMS2_k127_6941624_11 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 314.0
CMS2_k127_6941624_12 protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001425 276.0
CMS2_k127_6941624_13 Glycosyl transferase, family 4 K13007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003303 261.0
CMS2_k127_6941624_14 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000001531 220.0
CMS2_k127_6941624_15 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000003899 218.0
CMS2_k127_6941624_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000002983 209.0
CMS2_k127_6941624_17 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000001687 177.0
CMS2_k127_6941624_18 rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000003593 150.0
CMS2_k127_6941624_19 Domain of unknown function (DUF4124) - - - 0.00000000000000000000008683 105.0
CMS2_k127_6941624_2 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 3.564e-249 777.0
CMS2_k127_6941624_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 2.407e-218 688.0
CMS2_k127_6941624_4 CoA-binding domain - - - 1.029e-217 707.0
CMS2_k127_6941624_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 528.0
CMS2_k127_6941624_6 Belongs to the malate synthase family K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 490.0
CMS2_k127_6941624_7 RmlD substrate binding domain K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 449.0
CMS2_k127_6941624_8 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 418.0
CMS2_k127_6941624_9 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 404.0
CMS2_k127_6944956_0 2Fe-2S iron-sulfur cluster binding domain K03863 - - 0.0 1337.0
CMS2_k127_6944956_1 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding - - - 4.979e-252 800.0
CMS2_k127_6944956_10 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000003473 234.0
CMS2_k127_6944956_2 Bacterial protein of unknown function (DUF853) K06915 - - 1.818e-216 682.0
CMS2_k127_6944956_3 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 384.0
CMS2_k127_6944956_4 chemotaxis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 393.0
CMS2_k127_6944956_5 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 371.0
CMS2_k127_6944956_6 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 326.0
CMS2_k127_6944956_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 301.0
CMS2_k127_6944956_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000004105 249.0
CMS2_k127_6944956_9 [2Fe-2S] binding domain K00256,K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000001002 229.0
CMS2_k127_6956474_0 B12 binding domain K00548 - 2.1.1.13 0.0 1715.0
CMS2_k127_6956474_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 8.653e-197 631.0
CMS2_k127_6956474_10 protocatechuate 3,4-dioxygenase, alpha K00448 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000679 242.0
CMS2_k127_6956474_11 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000000007831 229.0
CMS2_k127_6956474_12 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000001561 208.0
CMS2_k127_6956474_13 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000002714 195.0
CMS2_k127_6956474_14 Small membrane protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000003338 133.0
CMS2_k127_6956474_15 Thioesterase superfamily - - - 0.00000000000000000003443 108.0
CMS2_k127_6956474_2 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 614.0
CMS2_k127_6956474_3 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 570.0
CMS2_k127_6956474_4 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 429.0
CMS2_k127_6956474_5 protocatechuate 3,4-dioxygenase, beta subunit' K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 358.0
CMS2_k127_6956474_6 AMP-binding enzyme C-terminal domain K04110,K20458 - 6.2.1.25,6.2.1.27,6.2.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 353.0
CMS2_k127_6956474_7 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 334.0
CMS2_k127_6956474_8 PFAM fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004223 284.0
CMS2_k127_6956474_9 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001023 273.0
CMS2_k127_737969_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1418.0
CMS2_k127_737969_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 1.699e-288 897.0
CMS2_k127_737969_10 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000006705 228.0
CMS2_k127_737969_11 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000001235 220.0
CMS2_k127_737969_12 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000008499 219.0
CMS2_k127_737969_13 OsmC-like protein K04063 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006970,GO:0006972,GO:0006979,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 - 0.000000000000000000000000000000000000000000000001339 178.0
CMS2_k127_737969_14 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.00000000000000000000000000000000000000000001271 165.0
CMS2_k127_737969_15 PAS fold - - - 0.00000000000000000000000000000000000000000008168 174.0
CMS2_k127_737969_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000003296 166.0
CMS2_k127_737969_17 Ankyrin repeat - - - 0.000002495 58.0
CMS2_k127_737969_2 Insulinase (Peptidase family M16) K07263 - - 5.729e-269 859.0
CMS2_k127_737969_3 chain 5 L K00341 - 1.6.5.3 6.089e-266 839.0
CMS2_k127_737969_4 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 2.624e-241 754.0
CMS2_k127_737969_5 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 565.0
CMS2_k127_737969_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009435 550.0
CMS2_k127_737969_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 339.0
CMS2_k127_737969_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002518 289.0
CMS2_k127_737969_9 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000001633 249.0
CMS2_k127_765856_0 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 461.0
CMS2_k127_765856_1 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 454.0
CMS2_k127_765856_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 359.0
CMS2_k127_765856_3 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 312.0
CMS2_k127_765856_4 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009064 242.0
CMS2_k127_765856_5 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000003686 207.0
CMS2_k127_765856_6 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000008077 173.0
CMS2_k127_765856_7 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000000001968 158.0
CMS2_k127_765856_8 Putative zinc-finger - - - 0.00000000003684 66.0
CMS2_k127_78293_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 6.052e-289 900.0
CMS2_k127_78293_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.631e-212 669.0
CMS2_k127_78293_10 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003787 262.0
CMS2_k127_78293_11 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000002375 211.0
CMS2_k127_78293_12 ChrR Cupin-like domain - - - 0.0000000000000000000000000000000000000000000005535 171.0
CMS2_k127_78293_13 Ankyrin repeat and kinase domain containing 1 K16289 - 2.7.11.1 0.00003671 55.0
CMS2_k127_78293_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 2.384e-196 621.0
CMS2_k127_78293_3 TIGRFAM amidase, hydantoinase carbamoylase family K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 520.0
CMS2_k127_78293_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 525.0
CMS2_k127_78293_5 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 476.0
CMS2_k127_78293_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 432.0
CMS2_k127_78293_7 PFAM fumarylacetoacetate (FAA) hydrolase K18336 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 411.0
CMS2_k127_78293_8 KR domain K00065 - 1.1.1.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 308.0
CMS2_k127_78293_9 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 299.0
CMS2_k127_792022_0 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 594.0
CMS2_k127_792022_1 amidohydrolase K03392,K07045 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 422.0
CMS2_k127_792022_2 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000176 242.0
CMS2_k127_792022_3 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000000000000000004443 131.0
CMS2_k127_807507_0 His Kinase A (phospho-acceptor) domain - - - 0.0 1200.0
CMS2_k127_807507_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1048.0
CMS2_k127_807507_10 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004954 287.0
CMS2_k127_807507_11 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002132 281.0
CMS2_k127_807507_12 LuxR family transcriptional regulator K13041 - - 0.0000000000000000000000000000000000000000000000000000000000009982 217.0
CMS2_k127_807507_13 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000007302 199.0
CMS2_k127_807507_14 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000004087 157.0
CMS2_k127_807507_15 E3 component of 2-oxoglutarate dehydrogenase complex K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.000000000000000001918 85.0
CMS2_k127_807507_16 - - - - 0.0000000001112 74.0
CMS2_k127_807507_2 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 8.556e-287 913.0
CMS2_k127_807507_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 4.861e-260 819.0
CMS2_k127_807507_4 dna polymerase iii K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 574.0
CMS2_k127_807507_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 495.0
CMS2_k127_807507_6 PFAM AFG1-family ATPase K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 441.0
CMS2_k127_807507_7 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008596 401.0
CMS2_k127_807507_8 Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 381.0
CMS2_k127_807507_9 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 383.0
CMS2_k127_859265_0 AMP binding - - - 7.627e-212 679.0
CMS2_k127_859265_1 general secretion pathway protein D K02453 - - 1.211e-203 662.0
CMS2_k127_859265_10 phosphorelay signal transduction system - - - 0.0000000000000000000000000003623 127.0
CMS2_k127_859265_12 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000004763 104.0
CMS2_k127_859265_13 general secretion pathway protein K02457 - - 0.0000000002508 72.0
CMS2_k127_859265_14 type II secretion system protein I J K02458 - - 0.000002392 58.0
CMS2_k127_859265_15 Type II secretion system protein C K02452 - - 0.0002847 51.0
CMS2_k127_859265_2 type II secretion system protein E K02454,K02652,K12276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 623.0
CMS2_k127_859265_3 Pyrroloquinoline quinone biosynthesis protein E - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 469.0
CMS2_k127_859265_4 General secretion pathway protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 364.0
CMS2_k127_859265_5 general secretion pathway protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000116 245.0
CMS2_k127_859265_6 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000000009051 220.0
CMS2_k127_859265_7 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000001016 185.0
CMS2_k127_859265_8 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.00000000000000000000000000000000004225 142.0
CMS2_k127_859265_9 PFAM General secretion pathway L K02461 - - 0.000000000000000000000000000007379 134.0
CMS2_k127_91612_0 FtsX-like permease family K02004 - - 3.638e-211 677.0
CMS2_k127_91612_1 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 439.0
CMS2_k127_95548_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 581.0
CMS2_k127_95548_1 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 477.0
CMS2_k127_95548_2 Permeases of the drug metabolite transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 308.0