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Overview

ID MAG00421
Name CMS2_bin.31
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order Anaerolineales
Family UBA11579
Genus UBA11579
Species UBA11579 sp035458505
Assembly information
Completeness (%) 68.65
Contamination (%) 1.65
GC content (%) 53.0
N50 (bp) 32,762
Genome size (bp) 2,412,305

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2036

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1072629_0 Heat shock 70 kDa protein K04043 - - 2.047e-301 935.0
CMS2_k127_1072629_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.208e-231 728.0
CMS2_k127_1072629_10 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 326.0
CMS2_k127_1072629_11 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 311.0
CMS2_k127_1072629_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 309.0
CMS2_k127_1072629_13 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 297.0
CMS2_k127_1072629_14 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003092 274.0
CMS2_k127_1072629_15 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000002182 222.0
CMS2_k127_1072629_16 ATPase-coupled phosphate ion transmembrane transporter activity K02036,K06857 - 3.6.3.27,3.6.3.55 0.00000000000000000000000000000000000000000000000000001484 193.0
CMS2_k127_1072629_17 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000001656 190.0
CMS2_k127_1072629_18 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000002452 195.0
CMS2_k127_1072629_19 LysM domain K02020 - - 0.000000000000000000000000000000000000000000004294 172.0
CMS2_k127_1072629_2 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 472.0
CMS2_k127_1072629_20 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000004167 161.0
CMS2_k127_1072629_21 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000003812 147.0
CMS2_k127_1072629_22 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.000000000000000000000000000000004809 132.0
CMS2_k127_1072629_23 - - - - 0.0000000000000000001202 97.0
CMS2_k127_1072629_24 - - - - 0.000000000001581 76.0
CMS2_k127_1072629_3 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 421.0
CMS2_k127_1072629_4 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 399.0
CMS2_k127_1072629_5 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 398.0
CMS2_k127_1072629_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 389.0
CMS2_k127_1072629_7 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 381.0
CMS2_k127_1072629_8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 380.0
CMS2_k127_1072629_9 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 347.0
CMS2_k127_1111292_0 CoA-ligase K02381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 590.0
CMS2_k127_1111292_1 Permease family K02824 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 533.0
CMS2_k127_1111292_10 PFAM PBS lyase HEAT-like repeat K02288,K02631 - 4.4.1.31,4.4.1.32 0.0002028 49.0
CMS2_k127_1111292_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 449.0
CMS2_k127_1111292_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433,K19837 - 3.5.1.84,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 429.0
CMS2_k127_1111292_4 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K11618 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 284.0
CMS2_k127_1111292_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001078 245.0
CMS2_k127_1111292_6 PFAM NmrA family protein - - - 0.0000000000000000000000000000000000000000000000008055 179.0
CMS2_k127_1111292_7 Domain of unknown function (DUF4332) - - - 0.000000000000000000000000000000000000005326 149.0
CMS2_k127_1111292_8 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000003447 150.0
CMS2_k127_113252_0 PFAM type II secretion system protein E K02283 - - 2.191e-217 682.0
CMS2_k127_113252_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 7.165e-198 623.0
CMS2_k127_113252_10 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000005157 234.0
CMS2_k127_113252_11 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000000000000000000002687 211.0
CMS2_k127_113252_12 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000005037 212.0
CMS2_k127_113252_14 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000002074 192.0
CMS2_k127_113252_15 Flp pilus assembly protein CpaB K02279 - - 0.000000000000000000000000000000000000000000000000008617 195.0
CMS2_k127_113252_16 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000002843 153.0
CMS2_k127_113252_17 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000004157 159.0
CMS2_k127_113252_18 competence protein - - - 0.0000000000000000000000000000000000000004419 157.0
CMS2_k127_113252_19 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000009649 132.0
CMS2_k127_113252_2 PFAM response regulator receiver K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 430.0
CMS2_k127_113252_20 TPR repeat - - - 0.0000000000000000000000000008741 117.0
CMS2_k127_113252_21 PFAM cyclic nucleotide-binding - - - 0.00000000000000000000000001713 115.0
CMS2_k127_113252_22 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633,K07589 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0008719,GO:0009987,GO:0016853,GO:0019752,GO:0034641,GO:0042558,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0071704,GO:1901360,GO:1901564 1.13.11.81,4.1.2.25,5.1.99.7,5.1.99.8 0.000000000000000000000005015 107.0
CMS2_k127_113252_23 SnoaL-like polyketide cyclase - - - 0.000000000000007162 78.0
CMS2_k127_113252_24 LysM domain K02020 - - 0.00000000001269 76.0
CMS2_k127_113252_26 Hypothetical glycosyl hydrolase family 13 K11931 - - 0.00000002748 65.0
CMS2_k127_113252_3 ATP hydrolysis coupled proton transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 416.0
CMS2_k127_113252_5 histidine kinase, dimerisation and phosphoacceptor region K07777 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 348.0
CMS2_k127_113252_6 PFAM type II secretion system protein K12510 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 336.0
CMS2_k127_113252_7 PFAM type II secretion system protein K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 329.0
CMS2_k127_113252_8 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001129 253.0
CMS2_k127_113252_9 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004926 250.0
CMS2_k127_1139631_0 membrane protein, required for spore maturation in B.subtilis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 303.0
CMS2_k127_1139631_1 Thioredoxin-like domain K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000001717 195.0
CMS2_k127_1139631_2 Domain of unknown function DUF123 - - - 0.0000000000000000001782 89.0
CMS2_k127_1140021_0 Bacterial type II and III secretion system protein K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 535.0
CMS2_k127_1153166_0 Short-chain dehydrogenase reductase SDR - - - 2.587e-228 723.0
CMS2_k127_1153166_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 507.0
CMS2_k127_1153166_10 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000004388 232.0
CMS2_k127_1153166_11 Ntpase (Nacht family) K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000005179 186.0
CMS2_k127_1153166_12 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000001569 156.0
CMS2_k127_1153166_13 Psort location CytoplasmicMembrane, score 9.46 - - - 0.00000000000000000000000000000000000008559 148.0
CMS2_k127_1153166_14 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000005102 138.0
CMS2_k127_1153166_15 Lysophospholipase L1 and related esterases - GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0044238,GO:0071704,GO:1901575 - 0.00000000000000007083 90.0
CMS2_k127_1153166_2 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 463.0
CMS2_k127_1153166_3 PFAM Methicillin resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 391.0
CMS2_k127_1153166_4 PFAM Methicillin resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 396.0
CMS2_k127_1153166_5 Pyridoxal-phosphate dependent enzyme K17950 - 4.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 364.0
CMS2_k127_1153166_6 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 353.0
CMS2_k127_1153166_7 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 335.0
CMS2_k127_1153166_8 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 337.0
CMS2_k127_1153166_9 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 286.0
CMS2_k127_1292488_0 SMART Polyketide synthase, beta-ketoacyl synthase region-containing protein, Polyketide synthase, phosphopantetheine-binding protein - - - 2.224e-223 709.0
CMS2_k127_1350979_0 DEAD DEAH box helicase domain protein K06877 - - 1.701e-298 939.0
CMS2_k127_1350979_1 elongation factor Tu domain 2 protein K06207 - - 1.726e-277 865.0
CMS2_k127_1350979_10 PhoQ Sensor K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007465 354.0
CMS2_k127_1350979_11 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 333.0
CMS2_k127_1350979_12 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 323.0
CMS2_k127_1350979_13 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 321.0
CMS2_k127_1350979_14 TOBE domain K02062,K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 308.0
CMS2_k127_1350979_15 FES K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 288.0
CMS2_k127_1350979_16 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 291.0
CMS2_k127_1350979_17 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000491 277.0
CMS2_k127_1350979_18 Protein of unknown function (DUF3048) C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007526 258.0
CMS2_k127_1350979_19 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004144 249.0
CMS2_k127_1350979_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 4.055e-267 840.0
CMS2_k127_1350979_20 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000001338 243.0
CMS2_k127_1350979_21 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000000000000002568 231.0
CMS2_k127_1350979_22 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000007916 233.0
CMS2_k127_1350979_23 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000001266 220.0
CMS2_k127_1350979_24 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000000000000000000000000000000001102 202.0
CMS2_k127_1350979_25 Domain of unknown function (DUF1989) K09967 - - 0.00000000000000000000000000000000000000000000000000009794 196.0
CMS2_k127_1350979_26 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000000000000005 191.0
CMS2_k127_1350979_27 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000005457 192.0
CMS2_k127_1350979_28 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000000000000000001028 187.0
CMS2_k127_1350979_29 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000256 189.0
CMS2_k127_1350979_3 Aminotransferase class-V K01556 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019441,GO:0019752,GO:0030429,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 590.0
CMS2_k127_1350979_30 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000005258 193.0
CMS2_k127_1350979_31 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000001408 177.0
CMS2_k127_1350979_32 Thiamin pyrophosphokinase, vitamin B1 binding domain K00949 - 2.7.6.2 0.000000000000000000000000000000000000000000008848 171.0
CMS2_k127_1350979_33 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000001789 168.0
CMS2_k127_1350979_34 mRNA catabolic process - - - 0.000000000000000000000000000000000000003419 153.0
CMS2_k127_1350979_35 Protein of unknown function (DUF402) K07586 - - 0.0000000000000000000000000000000002037 138.0
CMS2_k127_1350979_36 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000007637 131.0
CMS2_k127_1350979_37 Citrate transporter - - - 0.00000000000000000000000000001148 121.0
CMS2_k127_1350979_38 KR domain - - - 0.00000000000000000000000000006855 125.0
CMS2_k127_1350979_39 Thioesterase-like superfamily K07107 - - 0.000000000000000000000001301 109.0
CMS2_k127_1350979_4 thiamine transport K02063 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006855,GO:0008150,GO:0015234,GO:0015238,GO:0015893,GO:0016020,GO:0022857,GO:0035461,GO:0042221,GO:0042493,GO:0044464,GO:0045117,GO:0050896,GO:0051179,GO:0051180,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071934,GO:0071944,GO:0072348,GO:0072531,GO:0090482,GO:1901474,GO:1901682 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 578.0
CMS2_k127_1350979_40 - - - - 0.0000000000000000000002835 100.0
CMS2_k127_1350979_41 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.000000005999 66.0
CMS2_k127_1350979_42 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00005708 57.0
CMS2_k127_1350979_43 diguanylate cyclase - - - 0.0001151 55.0
CMS2_k127_1350979_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 460.0
CMS2_k127_1350979_6 L-asparaginase II K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006666 393.0
CMS2_k127_1350979_7 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008031 392.0
CMS2_k127_1350979_8 Bacterial extracellular solute-binding protein K02064 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 383.0
CMS2_k127_1350979_9 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 385.0
CMS2_k127_137381_0 PFAM Transposase K07491 - - 0.0000000000000000000000000000000000000000000000000000000004294 205.0
CMS2_k127_137381_1 - - - - 0.0000000000607 66.0
CMS2_k127_137381_2 - - - - 0.0001344 46.0
CMS2_k127_1454250_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.195e-230 729.0
CMS2_k127_1454250_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 6.945e-201 659.0
CMS2_k127_1454250_10 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 343.0
CMS2_k127_1454250_11 PFAM Haloacid dehalogenase domain protein hydrolase K02566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 316.0
CMS2_k127_1454250_12 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 308.0
CMS2_k127_1454250_13 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 296.0
CMS2_k127_1454250_14 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005278 271.0
CMS2_k127_1454250_15 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008707 280.0
CMS2_k127_1454250_16 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000006545 265.0
CMS2_k127_1454250_17 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000004079 210.0
CMS2_k127_1454250_18 dipeptide transport K02035 - - 0.000000000000000000000000000000000000000000000000000000003203 220.0
CMS2_k127_1454250_19 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000001621 183.0
CMS2_k127_1454250_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 535.0
CMS2_k127_1454250_20 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000002406 178.0
CMS2_k127_1454250_21 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000000003658 161.0
CMS2_k127_1454250_22 AsnC family K03718 - - 0.0000000000000000000000000000002035 130.0
CMS2_k127_1454250_23 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000001124 107.0
CMS2_k127_1454250_24 competence protein COMEC K02238 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000002137 103.0
CMS2_k127_1454250_25 YacP-like NYN domain K06962 - - 0.000000000000000000002119 99.0
CMS2_k127_1454250_26 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000000009541 81.0
CMS2_k127_1454250_27 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000003338 76.0
CMS2_k127_1454250_28 Golgi vesicle prefusion complex stabilization K19373 GO:0000301,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0006810,GO:0006890,GO:0006891,GO:0006996,GO:0007030,GO:0008150,GO:0009987,GO:0010256,GO:0012505,GO:0016043,GO:0016192,GO:0017119,GO:0022607,GO:0032991,GO:0034622,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0048193,GO:0048213,GO:0051179,GO:0051234,GO:0065003,GO:0071840,GO:0099023 - 0.0000000000008754 74.0
CMS2_k127_1454250_29 Mut7-C ubiquitin - - - 0.0000000007546 63.0
CMS2_k127_1454250_3 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 522.0
CMS2_k127_1454250_30 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000003472 57.0
CMS2_k127_1454250_31 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.0000004367 57.0
CMS2_k127_1454250_32 PFAM Thioredoxin K03671 - - 0.00003433 48.0
CMS2_k127_1454250_33 ABC transporter permease K02033 - - 0.0005401 43.0
CMS2_k127_1454250_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 498.0
CMS2_k127_1454250_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03851,K15372 - 2.6.1.55,2.6.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 437.0
CMS2_k127_1454250_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 409.0
CMS2_k127_1454250_7 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 395.0
CMS2_k127_1454250_8 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 379.0
CMS2_k127_1454250_9 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 372.0
CMS2_k127_1486108_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 3.672e-319 992.0
CMS2_k127_1486108_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 3.438e-291 913.0
CMS2_k127_1486108_10 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 288.0
CMS2_k127_1486108_11 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002881 273.0
CMS2_k127_1486108_12 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001317 266.0
CMS2_k127_1486108_13 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005282 258.0
CMS2_k127_1486108_14 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000001082 246.0
CMS2_k127_1486108_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004674 249.0
CMS2_k127_1486108_16 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000001096 232.0
CMS2_k127_1486108_17 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000662 212.0
CMS2_k127_1486108_18 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000008208 189.0
CMS2_k127_1486108_19 - - - - 0.0000000000000000000000000000000000000000000526 169.0
CMS2_k127_1486108_2 - Catabolite gene activator and regulatory subunit of cAMP-dependent protein - - - 4.413e-206 655.0
CMS2_k127_1486108_20 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000001504 129.0
CMS2_k127_1486108_21 Cold shock protein K03704 - - 0.00000000000000000000002731 101.0
CMS2_k127_1486108_22 GGDEF domain containing protein - - - 0.0000000000000000007525 91.0
CMS2_k127_1486108_24 Voltage gated chloride channel K03281 - - 0.00000161 56.0
CMS2_k127_1486108_3 CO dehydrogenase flavoprotein C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 568.0
CMS2_k127_1486108_4 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004774 421.0
CMS2_k127_1486108_5 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 407.0
CMS2_k127_1486108_6 TIGRFAM Competence protein ComEA, helix-hairpin-helix K17717 - 3.1.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 358.0
CMS2_k127_1486108_7 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 359.0
CMS2_k127_1486108_8 inorganic diphosphatase activity K15986 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 325.0
CMS2_k127_1486108_9 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 318.0
CMS2_k127_1501649_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 1.274e-206 649.0
CMS2_k127_1501649_1 NUDIX domain - - - 0.00000002354 55.0
CMS2_k127_1528512_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 5.731e-296 934.0
CMS2_k127_1528512_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 570.0
CMS2_k127_1528512_10 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005035 340.0
CMS2_k127_1528512_11 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002358 284.0
CMS2_k127_1528512_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000001021 220.0
CMS2_k127_1528512_14 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000006552 214.0
CMS2_k127_1528512_15 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000002065 201.0
CMS2_k127_1528512_16 PFAM major facilitator superfamily MFS_1 K08223 - - 0.00000000000000000000000000000000000000000000000000002359 202.0
CMS2_k127_1528512_17 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000000000000000000006843 190.0
CMS2_k127_1528512_18 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000000000000000005431 175.0
CMS2_k127_1528512_19 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000009966 182.0
CMS2_k127_1528512_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 562.0
CMS2_k127_1528512_20 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000006356 182.0
CMS2_k127_1528512_21 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07716 - 2.7.13.3 0.000000000000000000000000000000000000000005082 178.0
CMS2_k127_1528512_22 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000000000000000000000000001417 149.0
CMS2_k127_1528512_23 Uncharacterized conserved protein (DUF2294) - - - 0.00000000000000000000000000003992 120.0
CMS2_k127_1528512_24 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000005648 120.0
CMS2_k127_1528512_25 - - - - 0.000000000000000000000000001669 119.0
CMS2_k127_1528512_26 MazG nucleotide pyrophosphohydrolase domain - - - 0.00000000000000000000002754 103.0
CMS2_k127_1528512_27 - - - - 0.0000000000000000002486 92.0
CMS2_k127_1528512_28 ACT domain K09964 - - 0.0000003388 51.0
CMS2_k127_1528512_29 HWE histidine kinase - - - 0.00004719 55.0
CMS2_k127_1528512_3 Binding-protein-dependent transport systems inner membrane component K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 529.0
CMS2_k127_1528512_4 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 472.0
CMS2_k127_1528512_5 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 464.0
CMS2_k127_1528512_6 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 444.0
CMS2_k127_1528512_7 Bacterial extracellular solute-binding protein K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 399.0
CMS2_k127_1528512_8 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 399.0
CMS2_k127_1528512_9 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 392.0
CMS2_k127_1536239_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1335.0
CMS2_k127_1536239_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.655e-257 817.0
CMS2_k127_1536239_10 Peptidase family S41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 476.0
CMS2_k127_1536239_11 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 445.0
CMS2_k127_1536239_12 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 438.0
CMS2_k127_1536239_13 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 436.0
CMS2_k127_1536239_14 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 425.0
CMS2_k127_1536239_15 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 383.0
CMS2_k127_1536239_16 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 347.0
CMS2_k127_1536239_17 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 334.0
CMS2_k127_1536239_18 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 330.0
CMS2_k127_1536239_19 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 305.0
CMS2_k127_1536239_2 Penicillin amidase K01434 - 3.5.1.11 1.77e-213 687.0
CMS2_k127_1536239_20 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 292.0
CMS2_k127_1536239_21 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001998 304.0
CMS2_k127_1536239_22 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000472 273.0
CMS2_k127_1536239_23 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007164 276.0
CMS2_k127_1536239_24 spore germination K03298 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001001 261.0
CMS2_k127_1536239_25 Chloramphenicol acetyltransferase K19271 - 2.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000002572 247.0
CMS2_k127_1536239_26 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000001295 244.0
CMS2_k127_1536239_27 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000001897 241.0
CMS2_k127_1536239_28 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000004244 226.0
CMS2_k127_1536239_29 PFAM Vitamin K epoxide reductase - - - 0.00000000000000000000000000000000000000000000000000000000002817 221.0
CMS2_k127_1536239_3 BNR/Asp-box repeat - - - 1.47e-209 654.0
CMS2_k127_1536239_30 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000000000000000000000000000000000000005025 184.0
CMS2_k127_1536239_31 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000002531 181.0
CMS2_k127_1536239_32 - - - - 0.00000000000000000000000000000000000000000000000006871 181.0
CMS2_k127_1536239_33 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000009528 178.0
CMS2_k127_1536239_34 galactose-6-phosphate isomerase activity K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000001788 176.0
CMS2_k127_1536239_35 LysE type translocator - - - 0.000000000000000000000000000000000007215 144.0
CMS2_k127_1536239_36 Mo-molybdopterin cofactor metabolic process K03636,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000367 138.0
CMS2_k127_1536239_37 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000001813 130.0
CMS2_k127_1536239_38 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000000000000000001349 119.0
CMS2_k127_1536239_39 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.000000000000000000000000002702 112.0
CMS2_k127_1536239_4 PFAM fumarate lyase K01679 - 4.2.1.2 2.131e-200 634.0
CMS2_k127_1536239_40 PFAM zinc finger, SWIM domain protein - - - 0.000000000000000000000002377 104.0
CMS2_k127_1536239_41 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000000000001068 98.0
CMS2_k127_1536239_42 PFAM ferredoxin - - - 0.000000000000000000004182 102.0
CMS2_k127_1536239_43 - - - - 0.00000000000000000004538 95.0
CMS2_k127_1536239_44 Nodulation protein S (NodS) - - - 0.000000000000000009943 92.0
CMS2_k127_1536239_45 PspC domain K03973 - - 0.0000000000000002601 81.0
CMS2_k127_1536239_46 cytochrome complex assembly K02200,K04018 - - 0.000000000000002088 89.0
CMS2_k127_1536239_47 PFAM HD domain - - - 0.000000000000006162 81.0
CMS2_k127_1536239_5 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 558.0
CMS2_k127_1536239_50 domain, Protein - - - 0.0000000924 61.0
CMS2_k127_1536239_52 - - - - 0.000002436 52.0
CMS2_k127_1536239_53 domain, Protein - - - 0.000004605 53.0
CMS2_k127_1536239_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 537.0
CMS2_k127_1536239_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 497.0
CMS2_k127_1536239_8 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 487.0
CMS2_k127_1536239_9 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 468.0
CMS2_k127_1542368_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 2.346e-248 775.0
CMS2_k127_1542368_1 PFAM amidohydrolase K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 535.0
CMS2_k127_1542368_10 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 307.0
CMS2_k127_1542368_11 4-vinyl reductase, 4VR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 300.0
CMS2_k127_1542368_12 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 302.0
CMS2_k127_1542368_13 PFAM LmbE family protein K18455 - 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 296.0
CMS2_k127_1542368_14 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003972 264.0
CMS2_k127_1542368_15 Response regulator, receiver K02487,K03407,K03413,K06596,K11526,K13490 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004342 252.0
CMS2_k127_1542368_16 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009272 252.0
CMS2_k127_1542368_17 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000004009 251.0
CMS2_k127_1542368_18 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000000001877 238.0
CMS2_k127_1542368_19 PFAM glutamine amidotransferase class-I K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000008334 232.0
CMS2_k127_1542368_2 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 539.0
CMS2_k127_1542368_20 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000002036 233.0
CMS2_k127_1542368_21 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000003288 227.0
CMS2_k127_1542368_22 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000001221 224.0
CMS2_k127_1542368_23 CYTH domain K05873 - 4.6.1.1 0.000000000000000000000000000000000000000000000000003949 188.0
CMS2_k127_1542368_24 Domain of unknown function (DUF4395) - - - 0.00000000000000000000000000000000000000000000002238 175.0
CMS2_k127_1542368_25 PFAM Roadblock LC7 family protein K07131 - - 0.0000000000000000000000000000000000000000000002513 172.0
CMS2_k127_1542368_26 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000002588 152.0
CMS2_k127_1542368_27 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000001081 143.0
CMS2_k127_1542368_28 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000003275 146.0
CMS2_k127_1542368_29 JAB/MPN domain - - - 0.00000000000000000000000000000000008997 138.0
CMS2_k127_1542368_3 ThiF family K03148,K21029,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 475.0
CMS2_k127_1542368_30 Domain of unknown function DUF123 - - - 0.0000000000000000000000000000001528 130.0
CMS2_k127_1542368_31 Cell envelope-related transcriptional attenuator domain - - - 0.00000000000000000000000000005111 131.0
CMS2_k127_1542368_32 COG0526, thiol-disulfide isomerase and thioredoxins K03671 - - 0.0000000000000000000000002801 113.0
CMS2_k127_1542368_33 ThiS family K21029,K21147 - 2.7.7.80,2.8.1.11 0.00000000000000000000001747 102.0
CMS2_k127_1542368_34 Biotin-requiring enzyme - - - 0.00000000000000000000002959 109.0
CMS2_k127_1542368_35 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000002861 106.0
CMS2_k127_1542368_36 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000003236 105.0
CMS2_k127_1542368_37 Protein of unknown function (DUF1706) - - - 0.000000001413 66.0
CMS2_k127_1542368_38 Thioredoxin-like - - - 0.00002792 49.0
CMS2_k127_1542368_4 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 375.0
CMS2_k127_1542368_40 Belongs to the 'phage' integrase family K04763 - - 0.0002688 44.0
CMS2_k127_1542368_41 Belongs to the 'phage' integrase family K04763 - - 0.0008195 42.0
CMS2_k127_1542368_5 Belongs to the cysteine synthase cystathionine beta- synthase family K12339,K21148 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0033847,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.113,2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 366.0
CMS2_k127_1542368_6 Domain of unknown function (DUF348) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 345.0
CMS2_k127_1542368_7 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 321.0
CMS2_k127_1542368_8 PFAM Alcohol dehydrogenase, zinc-binding K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 323.0
CMS2_k127_1542368_9 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 317.0
CMS2_k127_154521_0 histidine kinase A domain protein - - - 0.0 1308.0
CMS2_k127_154521_1 Dienelactone hydrolase family - - - 5.261e-263 823.0
CMS2_k127_154521_10 PFAM ABC-3 protein K09816,K09819 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 319.0
CMS2_k127_154521_11 transferase activity, transferring glycosyl groups K21011,K21012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001333 283.0
CMS2_k127_154521_12 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006097 274.0
CMS2_k127_154521_13 PFAM ABC transporter related K09820,K11710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009904 276.0
CMS2_k127_154521_14 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001412 252.0
CMS2_k127_154521_15 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000005168 250.0
CMS2_k127_154521_16 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000002963 248.0
CMS2_k127_154521_17 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000137 239.0
CMS2_k127_154521_18 PFAM Acetyltransferase (GNAT) family K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000001364 228.0
CMS2_k127_154521_19 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000002389 169.0
CMS2_k127_154521_2 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 591.0
CMS2_k127_154521_20 - - - - 0.000000000000000000000000000000000000000001092 169.0
CMS2_k127_154521_21 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000000000000000000001718 154.0
CMS2_k127_154521_22 RNHCP domain - - - 0.00000000000000000000000000000004422 128.0
CMS2_k127_154521_23 - - - - 0.00000000000000000000001268 103.0
CMS2_k127_154521_24 Shikimate quinate 5-dehydrogenase - - - 0.0000000000000000000002297 99.0
CMS2_k127_154521_25 3-demethylubiquinone-9 3-O-methyltransferase activity K03428 - 2.1.1.11 0.00000000000000000001553 100.0
CMS2_k127_154521_26 Bacterial regulatory proteins, tetR family - - - 0.000000000000001612 84.0
CMS2_k127_154521_27 PFAM Forkhead-associated protein - - - 0.00000000000001438 79.0
CMS2_k127_154521_28 Helix-turn-helix domain - - - 0.00000000000001627 82.0
CMS2_k127_154521_29 AAA domain - - - 0.0000000000001786 78.0
CMS2_k127_154521_3 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007772 450.0
CMS2_k127_154521_30 Psort location Cytoplasmic, score 8.87 - - - 0.000000002417 68.0
CMS2_k127_154521_4 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 397.0
CMS2_k127_154521_5 HhH-GPD family K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 394.0
CMS2_k127_154521_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K18916 - 1.1.1.26,1.20.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 392.0
CMS2_k127_154521_7 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 377.0
CMS2_k127_154521_8 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 359.0
CMS2_k127_154521_9 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 329.0
CMS2_k127_1566158_0 elongation factor Tu domain 2 protein K02355 - - 1.18e-278 873.0
CMS2_k127_1566158_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 586.0
CMS2_k127_1566158_10 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006078 286.0
CMS2_k127_1566158_11 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001297 287.0
CMS2_k127_1566158_12 peptidase M24 K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005027 280.0
CMS2_k127_1566158_13 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009084 275.0
CMS2_k127_1566158_14 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002225 269.0
CMS2_k127_1566158_15 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003561 267.0
CMS2_k127_1566158_16 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000006512 257.0
CMS2_k127_1566158_17 homoserine kinase type II (protein kinase fold) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000294 250.0
CMS2_k127_1566158_18 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000002819 205.0
CMS2_k127_1566158_19 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000003614 187.0
CMS2_k127_1566158_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007711 527.0
CMS2_k127_1566158_20 methyltransferase activity K00569 - 2.1.1.67 0.00000000000000000000000000000000000000000000005894 175.0
CMS2_k127_1566158_21 Metallo-peptidase family M12B Reprolysin-like - - - 0.00000000000000000000000000000000000000000511 175.0
CMS2_k127_1566158_22 COG2335, Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000000000000000007785 163.0
CMS2_k127_1566158_23 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000001302 146.0
CMS2_k127_1566158_24 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000006853 137.0
CMS2_k127_1566158_25 - - - - 0.000000000000000000000000000000005369 139.0
CMS2_k127_1566158_27 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025,K20866 - 3.1.3.10 0.00000000000000000000000000003663 128.0
CMS2_k127_1566158_28 AntiSigma factor - - - 0.000000000000000000000001618 112.0
CMS2_k127_1566158_29 LysM domain K12204 - - 0.0000000000000000000009478 109.0
CMS2_k127_1566158_3 N-4 methylation of cytosine K00590 - 2.1.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 501.0
CMS2_k127_1566158_30 TIGRFAM phosphodiesterase, MJ0936 family K07095 - - 0.0000000000000000002035 90.0
CMS2_k127_1566158_31 ATP hydrolysis coupled proton transport - - - 0.000000000001752 80.0
CMS2_k127_1566158_32 PFAM blue (type 1) copper domain protein - - - 0.0000000001215 73.0
CMS2_k127_1566158_33 PFAM regulatory protein AsnC Lrp family - - - 0.000000313 55.0
CMS2_k127_1566158_4 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 432.0
CMS2_k127_1566158_5 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 396.0
CMS2_k127_1566158_6 Formate/nitrite transporter K06212 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 327.0
CMS2_k127_1566158_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 317.0
CMS2_k127_1566158_8 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 305.0
CMS2_k127_1566158_9 Fasciclin - GO:0005575,GO:0005576,GO:0005615,GO:0005623,GO:0005886,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043207,GO:0044403,GO:0044419,GO:0044421,GO:0044464,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071944,GO:0075136 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000298 288.0
CMS2_k127_1720080_0 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000000000000000000001306 226.0
CMS2_k127_1720080_1 Rieske [2Fe-2S] domain K03886 - - 0.00000000000000000000008225 102.0
CMS2_k127_172020_0 Pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 3.496e-210 661.0
CMS2_k127_172020_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 460.0
CMS2_k127_172020_2 e3 binding domain K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 314.0
CMS2_k127_172020_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000001246 188.0
CMS2_k127_172020_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000004598 160.0
CMS2_k127_172020_5 Methyltransferase domain K06987 - - 0.0000000000000000000000000000000000000002093 165.0
CMS2_k127_1733840_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 460.0
CMS2_k127_1733840_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 311.0
CMS2_k127_1733840_2 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008039 259.0
CMS2_k127_1733840_3 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000006674 187.0
CMS2_k127_1733840_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000004494 164.0
CMS2_k127_1733840_5 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000002356 116.0
CMS2_k127_1733840_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000007423 92.0
CMS2_k127_1899066_0 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 586.0
CMS2_k127_1899066_1 transporter - - - 0.00000000000000000000000000000000000000000000000000000000003459 216.0
CMS2_k127_1983818_0 - - - - 0.0000000000000000000007892 108.0
CMS2_k127_1983818_1 - - - - 0.000006514 53.0
CMS2_k127_1989715_0 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 577.0
CMS2_k127_1989715_1 PFAM conserved K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 449.0
CMS2_k127_1989715_10 Protein of unknown function (DUF3090) - - - 0.000000000000000000000000000000000000000000000000000000000000007185 220.0
CMS2_k127_1989715_11 transferase activity, transferring acyl groups - - - 0.000000000000000000000000000000000000000000000000000000003705 215.0
CMS2_k127_1989715_12 alpha-ribazole phosphatase activity K02226,K15634,K22305 - 3.1.3.3,3.1.3.73,5.4.2.12 0.000000000000000000000000000000000000000000000000005636 187.0
CMS2_k127_1989715_13 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000005865 107.0
CMS2_k127_1989715_15 Belongs to the 'phage' integrase family - - - 0.00000000000000002656 82.0
CMS2_k127_1989715_16 Protein of unknown function (DUF2812) - - - 0.0000000000000004684 85.0
CMS2_k127_1989715_17 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000005507 72.0
CMS2_k127_1989715_18 Belongs to the 'phage' integrase family - - - 0.00005571 47.0
CMS2_k127_1989715_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 421.0
CMS2_k127_1989715_20 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00005664 47.0
CMS2_k127_1989715_3 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 377.0
CMS2_k127_1989715_4 protein methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 325.0
CMS2_k127_1989715_5 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 301.0
CMS2_k127_1989715_6 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 299.0
CMS2_k127_1989715_7 TIGRFAM small GTP-binding protein K06945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 285.0
CMS2_k127_1989715_8 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003153 293.0
CMS2_k127_1989715_9 phosphatidylinositol kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005863 276.0
CMS2_k127_1998649_0 ATPase AAA-2 domain protein K03696 - - 9.146e-306 957.0
CMS2_k127_1998649_1 flavoprotein involved in K transport - GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 565.0
CMS2_k127_1998649_10 - - - - 0.000000000000000000000000000000000000000000000000000000006524 206.0
CMS2_k127_1998649_11 FMN reductase (NADPH) activity - - - 0.000000000000000000000000000000000000000000000000001351 190.0
CMS2_k127_1998649_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000648 173.0
CMS2_k127_1998649_13 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000141 184.0
CMS2_k127_1998649_14 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000001693 171.0
CMS2_k127_1998649_15 Cold shock protein domain K03704 - - 0.00000000000000000000000003491 108.0
CMS2_k127_1998649_16 iron-sulfur cluster assembly - - - 0.0000000000000000000000002064 109.0
CMS2_k127_1998649_17 Domain of unknown function (DUF4282) - - - 0.000000000005175 69.0
CMS2_k127_1998649_2 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 496.0
CMS2_k127_1998649_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 496.0
CMS2_k127_1998649_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 462.0
CMS2_k127_1998649_5 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 384.0
CMS2_k127_1998649_6 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 357.0
CMS2_k127_1998649_7 Heat shock protein DnaJ domain protein K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 324.0
CMS2_k127_1998649_8 Ribosomal protein S1 K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008846 328.0
CMS2_k127_1998649_9 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 303.0
CMS2_k127_2004235_0 GMC oxidoreductase - - - 4.393e-204 648.0
CMS2_k127_2004235_1 B3/4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001048 254.0
CMS2_k127_2004235_10 Belongs to the acetyltransferase family. ArgA subfamily K00537,K00619,K07755 - 1.20.4.1,2.1.1.137,2.3.1.1 0.000000000000000002148 90.0
CMS2_k127_2004235_11 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000002477 81.0
CMS2_k127_2004235_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000008541 77.0
CMS2_k127_2004235_13 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000006679 78.0
CMS2_k127_2004235_2 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000001702 216.0
CMS2_k127_2004235_3 Protein of unknown function (DUF4230) - - - 0.00000000000000000000000000000000000004365 152.0
CMS2_k127_2004235_4 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000004431 140.0
CMS2_k127_2004235_5 YjbR - - - 0.0000000000000000000000000000000000808 138.0
CMS2_k127_2004235_6 TIGRFAM Diguanylate cyclase - - - 0.000000000000000000000000000000000225 140.0
CMS2_k127_2004235_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000332 130.0
CMS2_k127_2004235_8 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000003154 98.0
CMS2_k127_2004235_9 Transcription factor zinc-finger - - - 0.0000000000000000000005596 103.0
CMS2_k127_2052691_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656,K03657 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0032392,GO:0032508,GO:0034641,GO:0034645,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044786,GO:0044787,GO:0046483,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000007881 268.0
CMS2_k127_2052691_1 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000001175 240.0
CMS2_k127_2077605_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 2.278e-279 878.0
CMS2_k127_2077605_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 2.398e-259 821.0
CMS2_k127_2077605_10 nodulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000909 237.0
CMS2_k127_2077605_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001676 233.0
CMS2_k127_2077605_12 pseudouridine synthase activity K06178,K06181,K06183 - 5.4.99.19,5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000002777 228.0
CMS2_k127_2077605_13 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000004245 214.0
CMS2_k127_2077605_14 IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000001302 208.0
CMS2_k127_2077605_15 - - - - 0.0000000000000000000000000000000000000000000000000000193 198.0
CMS2_k127_2077605_16 methyltransferase activity K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000002778 194.0
CMS2_k127_2077605_17 FR47-like protein K06976 - - 0.00000000000000000000000000000000000000000000008536 179.0
CMS2_k127_2077605_18 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000006683 149.0
CMS2_k127_2077605_19 - - - - 0.00000000000000000000000000000002696 135.0
CMS2_k127_2077605_2 Radical_SAM C-terminal domain K07739 - 2.3.1.48 4.056e-228 718.0
CMS2_k127_2077605_20 PFAM Stage V sporulation protein S K06416 - - 0.000000000000000000000000000001422 123.0
CMS2_k127_2077605_21 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000000005569 121.0
CMS2_k127_2077605_22 - - - - 0.0000000000000000000008496 104.0
CMS2_k127_2077605_23 WD-40 repeat - - - 0.0000000000000000005274 102.0
CMS2_k127_2077605_24 EamA-like transporter family - - - 0.000000000000007863 85.0
CMS2_k127_2077605_27 PFAM IS1 transposase K07480 - - 0.000002746 49.0
CMS2_k127_2077605_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 1.87e-205 649.0
CMS2_k127_2077605_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 499.0
CMS2_k127_2077605_5 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 454.0
CMS2_k127_2077605_6 Carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 402.0
CMS2_k127_2077605_7 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005144 278.0
CMS2_k127_2077605_8 PFAM deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002441 273.0
CMS2_k127_2077605_9 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000001999 249.0
CMS2_k127_2116265_0 PFAM Thioredoxin - GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000004553 60.0
CMS2_k127_2116265_1 Transcriptional regulator - - - 0.0008582 48.0
CMS2_k127_2121796_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008266 293.0
CMS2_k127_2121796_1 PFAM Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000003283 263.0
CMS2_k127_2122972_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043436,GO:0043937,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0045333,GO:0046459,GO:0047456,GO:0048037,GO:0050789,GO:0050793,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.0 1177.0
CMS2_k127_2122972_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008025 314.0
CMS2_k127_2122972_10 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.0000000000000000000968 99.0
CMS2_k127_2122972_11 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000004917 101.0
CMS2_k127_2122972_12 translation initiation factor activity - - - 0.00000000000000005934 85.0
CMS2_k127_2122972_13 - - - - 0.0000000000003255 82.0
CMS2_k127_2122972_14 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000003233 63.0
CMS2_k127_2122972_2 Domain of unknown function DUF87 K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 293.0
CMS2_k127_2122972_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001708 278.0
CMS2_k127_2122972_5 NurA - - - 0.00000000000000000000000000000000000000000000000000000000005025 219.0
CMS2_k127_2122972_6 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000005806 190.0
CMS2_k127_2122972_7 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000002585 126.0
CMS2_k127_2122972_8 Domain of unknown function (DUF4259) - - - 0.00000000000000000000000000003312 121.0
CMS2_k127_2122972_9 PFAM AAA ATPase central domain protein K07478 - - 0.000000000000000000000000007609 113.0
CMS2_k127_2140077_0 PFAM alpha-2-macroglobulin domain protein K06894 - - 0.0 1198.0
CMS2_k127_2140077_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 1.439e-219 687.0
CMS2_k127_2140077_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009031 259.0
CMS2_k127_2140077_11 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003235 248.0
CMS2_k127_2140077_12 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000022 211.0
CMS2_k127_2140077_13 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.00000000000000000000000000000000000003073 152.0
CMS2_k127_2140077_14 Trypsin-like peptidase domain K08372 - - 0.0000000000000000000000000000177 134.0
CMS2_k127_2140077_15 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000002709 127.0
CMS2_k127_2140077_16 Protein of unknown function (DUF1232) - - - 0.00000000000000000000003584 104.0
CMS2_k127_2140077_17 PFAM UspA domain protein - - - 0.0000000000378 73.0
CMS2_k127_2140077_18 - - - - 0.00000000003953 72.0
CMS2_k127_2140077_19 Heat shock protein DnaJ domain protein - - - 0.00000000746 66.0
CMS2_k127_2140077_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 582.0
CMS2_k127_2140077_20 PFAM Abortive infection protein - - - 0.0007727 50.0
CMS2_k127_2140077_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 506.0
CMS2_k127_2140077_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 354.0
CMS2_k127_2140077_5 SMART Nucleotide binding protein, PINc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 323.0
CMS2_k127_2140077_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 295.0
CMS2_k127_2140077_7 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K11618 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001062 286.0
CMS2_k127_2140077_8 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005313 278.0
CMS2_k127_2140077_9 PFAM Thioredoxin domain K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007898 261.0
CMS2_k127_2160604_0 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000007007 182.0
CMS2_k127_2160604_1 Part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000000000000001676 169.0
CMS2_k127_2160604_2 - - - - 0.000000000000000000000000000000000000002597 154.0
CMS2_k127_2204027_0 transposase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005436 286.0
CMS2_k127_2204027_1 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000002321 160.0
CMS2_k127_2213154_0 PFAM short-chain dehydrogenase reductase SDR K15314 - - 2.011e-254 818.0
CMS2_k127_2213154_1 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0000000000001745 75.0
CMS2_k127_2228336_0 histidine kinase A domain protein - - - 0.0 1120.0
CMS2_k127_2228336_1 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.0 1018.0
CMS2_k127_2228336_10 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009812 447.0
CMS2_k127_2228336_11 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 415.0
CMS2_k127_2228336_12 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 362.0
CMS2_k127_2228336_13 Uncharacterised ACR (DUF711) K09157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 335.0
CMS2_k127_2228336_14 4-phosphoerythronate dehydrogenase activity K00058,K00122 - 1.1.1.399,1.1.1.95,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 308.0
CMS2_k127_2228336_15 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009438 308.0
CMS2_k127_2228336_16 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 289.0
CMS2_k127_2228336_17 PFAM metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007911 282.0
CMS2_k127_2228336_18 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001747 261.0
CMS2_k127_2228336_19 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001955 283.0
CMS2_k127_2228336_2 PFAM cell divisionFtsK SpoIIIE K03466 - - 1.083e-226 727.0
CMS2_k127_2228336_20 CBS domain containing protein K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000338 263.0
CMS2_k127_2228336_21 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001287 243.0
CMS2_k127_2228336_22 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000000348 235.0
CMS2_k127_2228336_23 FIST N domain - - - 0.000000000000000000000000000000000000000000000000000000000000001379 232.0
CMS2_k127_2228336_24 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000000000000000000000000000000001351 225.0
CMS2_k127_2228336_25 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000002746 224.0
CMS2_k127_2228336_26 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000001303 220.0
CMS2_k127_2228336_27 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000001082 231.0
CMS2_k127_2228336_28 PFAM Haloacid dehalogenase domain protein hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000286 203.0
CMS2_k127_2228336_29 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000009945 210.0
CMS2_k127_2228336_3 PFAM ABC transporter transmembrane region - - - 1.062e-210 670.0
CMS2_k127_2228336_30 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000002807 195.0
CMS2_k127_2228336_32 COGs COG0317 Guanosine polyphosphate pyrophosphohydrolase synthetase - - - 0.00000000000000000000000000000000000000000000000003742 184.0
CMS2_k127_2228336_33 Cupin domain - - - 0.00000000000000000000000000000000000000000000000219 175.0
CMS2_k127_2228336_34 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000001008 168.0
CMS2_k127_2228336_35 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000003449 177.0
CMS2_k127_2228336_37 - - - - 0.0000000000000000000000000000000000000003644 158.0
CMS2_k127_2228336_38 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000000001131 147.0
CMS2_k127_2228336_39 Protein of unknown function (DUF2089) - - - 0.00000000000000000000000000000001873 130.0
CMS2_k127_2228336_4 ABC transporter, transmembrane region K06147 - - 1.385e-201 643.0
CMS2_k127_2228336_40 phosphorelay signal transduction system - - - 0.000000000000000000000000000000161 137.0
CMS2_k127_2228336_41 - - - - 0.00000000000000000000000000005136 121.0
CMS2_k127_2228336_42 Gcn5-related n-acetyltransferase - - - 0.0000000000000000000000000001317 122.0
CMS2_k127_2228336_43 - - - - 0.00000000000000000000001822 108.0
CMS2_k127_2228336_44 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.0000000000000000000004069 107.0
CMS2_k127_2228336_45 Acyl-ACP thioesterase K07107 - - 0.000000000000000000001012 106.0
CMS2_k127_2228336_46 phosphatase activity K07025 - - 0.00000000000000000001846 100.0
CMS2_k127_2228336_47 Putative regulatory protein - - - 0.000000000000000002189 88.0
CMS2_k127_2228336_48 - - - - 0.000000000000000004566 92.0
CMS2_k127_2228336_49 Gaf domain - - - 0.000000000000001595 85.0
CMS2_k127_2228336_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 557.0
CMS2_k127_2228336_51 trisaccharide binding - - - 0.000000006281 70.0
CMS2_k127_2228336_53 PFAM HlyD family secretion protein K02022 - - 0.00007782 53.0
CMS2_k127_2228336_54 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K10912 GO:0000156,GO:0000160,GO:0003674,GO:0003700,GO:0006355,GO:0007154,GO:0007165,GO:0008150,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0023052,GO:0031323,GO:0031326,GO:0035556,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.0003061 48.0
CMS2_k127_2228336_55 CAAX protease self-immunity K07052 - - 0.0004763 51.0
CMS2_k127_2228336_6 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 549.0
CMS2_k127_2228336_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 555.0
CMS2_k127_2228336_8 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 545.0
CMS2_k127_2228336_9 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 452.0
CMS2_k127_2232752_0 - - - - 0.00001184 51.0
CMS2_k127_225399_0 peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 418.0
CMS2_k127_225399_1 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.0000000000000000002255 98.0
CMS2_k127_2259248_0 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 567.0
CMS2_k127_2259248_1 channel protein, hemolysin III family K11068 - - 0.0000000000000000000000000000000000000000000000000000000005029 208.0
CMS2_k127_2259248_2 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.0000000000000003914 79.0
CMS2_k127_2259248_3 cytochrome P450 K09837 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009507,GO:0009526,GO:0009536,GO:0009941,GO:0009974,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016491,GO:0016705,GO:0031967,GO:0031975,GO:0042440,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046148,GO:0055114,GO:0071704,GO:0072374,GO:1901576 1.14.99.45 0.00000000003329 65.0
CMS2_k127_2298489_0 Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 420.0
CMS2_k127_2298489_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 389.0
CMS2_k127_2298489_10 PFAM Cupin 2 conserved barrel domain protein - - - 0.00000000000000000000000003693 111.0
CMS2_k127_2298489_11 Pfam:DUF162 K00782 - - 0.0000000000000000000000005318 113.0
CMS2_k127_2298489_12 - - - - 0.0000000000000000000000006639 121.0
CMS2_k127_2298489_14 serine-type endopeptidase activity - - - 0.00000000000001085 81.0
CMS2_k127_2298489_15 Domain of unknown function - - - 0.0002699 44.0
CMS2_k127_2298489_16 - - - - 0.0009541 50.0
CMS2_k127_2298489_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 378.0
CMS2_k127_2298489_3 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 389.0
CMS2_k127_2298489_4 periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 334.0
CMS2_k127_2298489_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009232 283.0
CMS2_k127_2298489_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003379 247.0
CMS2_k127_2298489_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003064 254.0
CMS2_k127_2298489_8 Cysteine-rich domain K18928 - - 0.00000000000000000000000000000000000000000000000000000000000007634 222.0
CMS2_k127_2298489_9 PFAM ABC transporter related K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000002406 217.0
CMS2_k127_2330898_0 Glycyl-tRNA synthetase alpha subunit K14164 - 6.1.1.14 0.0 1198.0
CMS2_k127_2330898_1 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 596.0
CMS2_k127_2330898_10 acetyltransferase - - - 0.000000000000000000000000000000000000000000002903 174.0
CMS2_k127_2330898_11 COGs COG1653 ABC-type sugar transport system periplasmic component K02027 - - 0.000000000000000000000000000000000000000000176 177.0
CMS2_k127_2330898_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000006578 140.0
CMS2_k127_2330898_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.000000000000000000000000000002156 123.0
CMS2_k127_2330898_14 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000004489 87.0
CMS2_k127_2330898_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 400.0
CMS2_k127_2330898_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 385.0
CMS2_k127_2330898_4 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000001333 240.0
CMS2_k127_2330898_5 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001427 229.0
CMS2_k127_2330898_6 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000001273 218.0
CMS2_k127_2330898_7 - - - - 0.00000000000000000000000000000000000000000000000000006938 190.0
CMS2_k127_2330898_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000003018 173.0
CMS2_k127_2330898_9 LysM domain - - - 0.000000000000000000000000000000000000000000001612 176.0
CMS2_k127_2340850_0 PFAM Transposase DDE domain K07495 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 479.0
CMS2_k127_2340850_1 NADPH quinone reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 311.0
CMS2_k127_2341886_0 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009815 402.0
CMS2_k127_2341886_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000008685 223.0
CMS2_k127_2341886_2 Shikimate kinase - - - 0.00000000000000000000000000000000000000000001248 168.0
CMS2_k127_2341886_3 Methionine biosynthesis protein MetW K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000312 162.0
CMS2_k127_237001_0 Oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 559.0
CMS2_k127_237001_1 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000004153 66.0
CMS2_k127_237001_2 Creatinase/Prolidase N-terminal domain K01262,K01271 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0030145,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.9,3.4.13.9 0.00041 49.0
CMS2_k127_2387980_0 Conserved TM helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008209 274.0
CMS2_k127_2387980_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000007125 117.0
CMS2_k127_2387980_2 Transcriptional regulator - - - 0.000000000000001822 78.0
CMS2_k127_2387980_3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0002039 47.0
CMS2_k127_2453687_0 peptidase M29 aminopeptidase II K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001159 259.0
CMS2_k127_2453687_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000005255 184.0
CMS2_k127_2479417_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 2.19e-270 845.0
CMS2_k127_2479417_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001328 282.0
CMS2_k127_2479417_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000009226 91.0
CMS2_k127_2479417_11 PFAM Peptidase family M20 M25 M40 - - - 0.00000000000391 67.0
CMS2_k127_2479417_12 Domain of unknown function (DU1801) - - - 0.0001358 49.0
CMS2_k127_2479417_2 energy transducer activity K03531,K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001246 290.0
CMS2_k127_2479417_3 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001212 257.0
CMS2_k127_2479417_4 glucan 1,4-alpha-glucosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002587 257.0
CMS2_k127_2479417_5 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000001587 160.0
CMS2_k127_2479417_6 Smr domain - - - 0.00000000000000000000000000000000000008005 143.0
CMS2_k127_2479417_7 DinB family - - - 0.0000000000000000000000000001626 120.0
CMS2_k127_2479417_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000449 94.0
CMS2_k127_2479417_9 - - - - 0.000000000000000002288 94.0
CMS2_k127_2492832_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000007521 252.0
CMS2_k127_2492832_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000177 206.0
CMS2_k127_2509696_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 510.0
CMS2_k127_2509696_1 amino acid activation for nonribosomal peptide biosynthetic process K14379 - 3.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 313.0
CMS2_k127_2509696_2 PFAM peptidase M1, membrane alanine aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000001748 223.0
CMS2_k127_2509696_3 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000005541 187.0
CMS2_k127_2509696_4 Domain of unknown function (DUF4349) - - - 0.000000000000000000000008065 114.0
CMS2_k127_2608745_0 Belongs to the peptidase S8 family - - - 0.000000003569 70.0
CMS2_k127_2627190_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 347.0
CMS2_k127_2627190_1 Dodecin K09165 - - 0.0000000000000000000000003725 107.0
CMS2_k127_2665037_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 4.541e-232 722.0
CMS2_k127_2665037_1 uridine kinase K00876 - 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 531.0
CMS2_k127_2665037_10 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000002909 161.0
CMS2_k127_2665037_12 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000004372 119.0
CMS2_k127_2665037_14 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000121 57.0
CMS2_k127_2665037_15 EthD domain - - - 0.0004444 48.0
CMS2_k127_2665037_2 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 352.0
CMS2_k127_2665037_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 321.0
CMS2_k127_2665037_4 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 319.0
CMS2_k127_2665037_5 aminoglycoside 3-N-acetyltransferase activity K00662 - 2.3.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000142 277.0
CMS2_k127_2665037_6 heme binding K21472 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007416 256.0
CMS2_k127_2665037_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003286 254.0
CMS2_k127_2665037_8 Hydrophobic domain - - - 0.00000000000000000000000000000000000000000005299 179.0
CMS2_k127_2665037_9 enterobactin catabolic process K07214 - - 0.0000000000000000000000000000000000000002231 161.0
CMS2_k127_279198_0 ABC transporter K06147 - - 4.294e-281 876.0
CMS2_k127_279198_1 ABC transporter K06147 - - 6.446e-271 852.0
CMS2_k127_279198_2 CAAX protease self-immunity K07052 - - 0.00000000000000000001215 101.0
CMS2_k127_279198_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000003586 64.0
CMS2_k127_279198_4 PFAM TadE family protein - - - 0.000000004874 66.0
CMS2_k127_279198_5 short-chain dehydrogenase K00034 - 1.1.1.47 0.0001172 44.0
CMS2_k127_2910604_0 COGs COG1132 ABC-type multidrug transport system ATPase and permease components K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 571.0
CMS2_k127_2910604_1 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 566.0
CMS2_k127_2910604_10 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.00000008711 64.0
CMS2_k127_2910604_11 function. Source PGD - - - 0.000009105 56.0
CMS2_k127_2910604_12 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000009178 50.0
CMS2_k127_2910604_2 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 473.0
CMS2_k127_2910604_3 Reductive dehalogenase subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 369.0
CMS2_k127_2910604_4 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008589 319.0
CMS2_k127_2910604_5 glycosyl transferase group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000000000000000004123 249.0
CMS2_k127_2910604_6 Bacterial PH domain - - - 0.0000000000000000000000000000000000000000000000000000000000348 211.0
CMS2_k127_2910604_7 LacY proton/sugar symporter - - - 0.00000000000000000000000000000000000000000000000001076 195.0
CMS2_k127_2910604_8 Magnesium chelatase, subunit ChlI C-terminal K06400,K07391 - - 0.000000000000000000000000000000000000000000000001124 177.0
CMS2_k127_2940131_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000002403 171.0
CMS2_k127_2948961_0 AAA ATPase domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 413.0
CMS2_k127_3006632_0 PFAM Transketolase central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 564.0
CMS2_k127_3006632_1 FAD linked oxidase domain protein K00103,K16653 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576 1.1.3.8,1.1.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 501.0
CMS2_k127_3006632_11 histone H2A K63-linked ubiquitination - - - 0.0000000000000000000000000004019 121.0
CMS2_k127_3006632_12 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.0000000000000003548 86.0
CMS2_k127_3006632_2 Heparinase II/III-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 508.0
CMS2_k127_3006632_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 486.0
CMS2_k127_3006632_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 466.0
CMS2_k127_3006632_5 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 402.0
CMS2_k127_3006632_6 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00162,K00627 - 1.2.4.1,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 356.0
CMS2_k127_3006632_7 Trypsin-like serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000001355 222.0
CMS2_k127_3006632_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K16652 - 1.1.1.333 0.000000000000000000000000000000000000000000000000000000000001013 218.0
CMS2_k127_3006632_9 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000018 143.0
CMS2_k127_3094797_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001833 289.0
CMS2_k127_3106212_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 1.055e-293 914.0
CMS2_k127_3106212_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.91e-276 873.0
CMS2_k127_3106212_10 PFAM molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 396.0
CMS2_k127_3106212_11 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 387.0
CMS2_k127_3106212_12 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 380.0
CMS2_k127_3106212_13 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 381.0
CMS2_k127_3106212_14 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 365.0
CMS2_k127_3106212_15 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 340.0
CMS2_k127_3106212_16 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 323.0
CMS2_k127_3106212_17 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 310.0
CMS2_k127_3106212_18 protein (ATP-grasp superfamily) K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005712 266.0
CMS2_k127_3106212_19 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001551 259.0
CMS2_k127_3106212_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.036e-254 800.0
CMS2_k127_3106212_20 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000003551 244.0
CMS2_k127_3106212_21 regulatory protein LysR K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000004099 241.0
CMS2_k127_3106212_22 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000936 224.0
CMS2_k127_3106212_23 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000000000000000000181 201.0
CMS2_k127_3106212_24 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.00000000000000000000000000000000000000000000000000000239 196.0
CMS2_k127_3106212_25 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000001393 183.0
CMS2_k127_3106212_26 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000000000002747 170.0
CMS2_k127_3106212_27 response to abiotic stimulus - - - 0.0000000000000000000000000000000000000000004122 165.0
CMS2_k127_3106212_28 Inorganic pyrophosphatase - - - 0.00000000000000000000000000000000000000001716 155.0
CMS2_k127_3106212_29 GGDEF domain K13069 - 2.7.7.65 0.00000000000000000000000000000000000002962 157.0
CMS2_k127_3106212_3 Serine threonine protein kinase K12132 - 2.7.11.1 1.217e-244 770.0
CMS2_k127_3106212_30 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000003554 154.0
CMS2_k127_3106212_31 Asp23 family, cell envelope-related function - - - 0.0000000000000000000000000000000000001973 143.0
CMS2_k127_3106212_32 PFAM Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000894 137.0
CMS2_k127_3106212_33 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000001327 126.0
CMS2_k127_3106212_34 integral membrane protein - - - 0.000000000000000000000000000001975 135.0
CMS2_k127_3106212_35 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000002461 117.0
CMS2_k127_3106212_36 - - - - 0.00000000000000000000000659 102.0
CMS2_k127_3106212_37 Belongs to the peptidase S8 family - - - 0.0000000000000000000001949 107.0
CMS2_k127_3106212_38 - - - - 0.0000000000000000003134 93.0
CMS2_k127_3106212_39 ribosomal protein L28 K02902 - - 0.0000000000000000003676 87.0
CMS2_k127_3106212_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 1.465e-216 685.0
CMS2_k127_3106212_40 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000001396 81.0
CMS2_k127_3106212_41 COG1404 Subtilisin-like serine proteases K12685,K20754 - 3.4.21.111 0.00000000001446 74.0
CMS2_k127_3106212_42 Putative regulatory protein - - - 0.000000005706 59.0
CMS2_k127_3106212_43 DinB family - - - 0.0000355 51.0
CMS2_k127_3106212_5 PFAM Dak phosphatase K07030 - - 5.766e-202 644.0
CMS2_k127_3106212_6 PFAM peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 601.0
CMS2_k127_3106212_7 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 535.0
CMS2_k127_3106212_8 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 516.0
CMS2_k127_3106212_9 isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 451.0
CMS2_k127_3112724_0 Phytoene dehydrogenase K09835 - 5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 530.0
CMS2_k127_3112724_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 344.0
CMS2_k127_3112724_2 light absorption K06893 - - 0.00000000000000000000000000000000000000000000000000000000001223 209.0
CMS2_k127_3112724_3 sequence-specific DNA binding - - - 0.00000000000008247 77.0
CMS2_k127_3112724_4 CAAX amino terminal protease family K07052 - - 0.0000002698 61.0
CMS2_k127_313191_0 PFAM single-stranded nucleic acid binding R3H domain protein - - - 1.072e-217 687.0
CMS2_k127_313191_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 323.0
CMS2_k127_313191_10 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000265 148.0
CMS2_k127_313191_11 - - - - 0.0000000000000000000000001364 120.0
CMS2_k127_313191_12 Tellurite resistance protein TehB K16868 - 2.1.1.265 0.0000000000000000000416 97.0
CMS2_k127_313191_13 - - - - 0.00000000000000000004934 101.0
CMS2_k127_313191_14 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000007552 59.0
CMS2_k127_313191_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 289.0
CMS2_k127_313191_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000002442 240.0
CMS2_k127_313191_4 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000008093 239.0
CMS2_k127_313191_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004776 235.0
CMS2_k127_313191_6 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000000000000007816 201.0
CMS2_k127_313191_7 Guanylate kinase homologues. K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000003737 194.0
CMS2_k127_313191_8 Putative regulatory protein - - - 0.00000000000000000000000000000000000000000009659 162.0
CMS2_k127_313191_9 translation initiation factor activity K06996 - - 0.000000000000000000000000000000000000001893 150.0
CMS2_k127_3174298_0 COG2366 Protein related to penicillin acylase K01434,K07116 - 3.5.1.11,3.5.1.97 1.487e-218 700.0
CMS2_k127_3174298_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 436.0
CMS2_k127_3174298_10 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004959 258.0
CMS2_k127_3174298_11 Lipid kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008208 249.0
CMS2_k127_3174298_12 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003379 247.0
CMS2_k127_3174298_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001057 235.0
CMS2_k127_3174298_14 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000002135 228.0
CMS2_k127_3174298_15 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000005149 225.0
CMS2_k127_3174298_16 PFAM Cytochrome bd ubiquinol oxidase, subunit I K00425 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000002042 217.0
CMS2_k127_3174298_17 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000006473 224.0
CMS2_k127_3174298_18 B12 binding domain K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000003932 216.0
CMS2_k127_3174298_19 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000000000000000000000000001536 203.0
CMS2_k127_3174298_2 PFAM aminotransferase class V K04127 - 5.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 431.0
CMS2_k127_3174298_20 Domain of unknown function (DUF4386) - - - 0.000000000000000000000000000000000000000000000000008366 190.0
CMS2_k127_3174298_21 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000889 188.0
CMS2_k127_3174298_22 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.00000000000000000000000000000000000000000000000002304 188.0
CMS2_k127_3174298_23 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000000000000000000007375 150.0
CMS2_k127_3174298_24 PFAM peptidase M14, carboxypeptidase A - - - 0.0000000000000000000000000057 123.0
CMS2_k127_3174298_25 PFAM Forkhead-associated protein - - - 0.0000000000000000000000002298 120.0
CMS2_k127_3174298_26 transcriptional regulator K07729 - - 0.000000000000000000003204 97.0
CMS2_k127_3174298_27 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000005145 104.0
CMS2_k127_3174298_28 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000004056 99.0
CMS2_k127_3174298_29 Acetyltransferase (GNAT) domain - - - 0.00000000000000007851 91.0
CMS2_k127_3174298_3 PFAM Cytochrome bd ubiquinol oxidase, subunit II K00426 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 428.0
CMS2_k127_3174298_30 PFAM Cytochrome b5-like Heme Steroid binding domain - - - 0.000000000000004721 77.0
CMS2_k127_3174298_32 - - - - 0.000000000009346 68.0
CMS2_k127_3174298_33 AI-2E family transporter - - - 0.0000000006382 71.0
CMS2_k127_3174298_35 FecR protein - - - 0.000001324 58.0
CMS2_k127_3174298_36 Polymer-forming cytoskeletal - - - 0.00001611 57.0
CMS2_k127_3174298_37 - - - - 0.0004584 47.0
CMS2_k127_3174298_38 - - - - 0.0008015 48.0
CMS2_k127_3174298_4 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 382.0
CMS2_k127_3174298_5 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 371.0
CMS2_k127_3174298_6 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 368.0
CMS2_k127_3174298_7 CPA2 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 326.0
CMS2_k127_3174298_8 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005877 269.0
CMS2_k127_3174298_9 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000007181 267.0
CMS2_k127_321098_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 327.0
CMS2_k127_321098_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000004618 221.0
CMS2_k127_3229372_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.029e-234 735.0
CMS2_k127_3229372_1 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 293.0
CMS2_k127_3229372_2 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008232 267.0
CMS2_k127_3229372_3 - - - - 0.0000000000000000000000000000000000000000000000000000000003706 209.0
CMS2_k127_3229372_4 - - - - 0.00000000000000000000000000000000000000000000000000000001306 210.0
CMS2_k127_3229372_5 domain, Protein - - - 0.0000000000000000000000000000000000000000009682 169.0
CMS2_k127_3229372_6 - - - - 0.0000000000000000000000000000166 122.0
CMS2_k127_3229372_7 Belongs to the universal stress protein A family - - - 0.000000000000000003075 100.0
CMS2_k127_3229372_8 Amino acid permease - - - 0.0000000000000001964 94.0
CMS2_k127_3229372_9 - - - - 0.00000005936 60.0
CMS2_k127_3237217_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 464.0
CMS2_k127_3237217_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 443.0
CMS2_k127_3237217_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000001502 164.0
CMS2_k127_3237217_11 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000003708 163.0
CMS2_k127_3237217_12 Flavodoxin domain - - - 0.0000000000000000000002736 102.0
CMS2_k127_3237217_15 transcriptional regulator - - - 0.0000000004379 68.0
CMS2_k127_3237217_16 alpha/beta hydrolase fold K01259 - 3.4.11.5 0.0000001312 63.0
CMS2_k127_3237217_2 protein histidine kinase activity K10819 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 376.0
CMS2_k127_3237217_3 PFAM response regulator receiver K07658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 317.0
CMS2_k127_3237217_4 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 291.0
CMS2_k127_3237217_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001956 246.0
CMS2_k127_3237217_6 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000003175 222.0
CMS2_k127_3237217_7 metallopeptidase activity K20276 - - 0.0000000000000000000000000000000000000000000000004576 200.0
CMS2_k127_3237217_8 NUDIX hydrolase - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.000000000000000000000000000000000000000000000001399 181.0
CMS2_k127_3237217_9 domain protein - - - 0.00000000000000000000000000000000000000000000001893 195.0
CMS2_k127_3240111_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1237.0
CMS2_k127_3240111_1 - - - - 2.753e-254 807.0
CMS2_k127_3240111_10 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 520.0
CMS2_k127_3240111_11 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 511.0
CMS2_k127_3240111_12 PFAM major facilitator superfamily MFS_1 K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 496.0
CMS2_k127_3240111_13 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 445.0
CMS2_k127_3240111_14 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 421.0
CMS2_k127_3240111_15 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 411.0
CMS2_k127_3240111_16 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 377.0
CMS2_k127_3240111_17 V-type ATPase 116kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 386.0
CMS2_k127_3240111_18 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 361.0
CMS2_k127_3240111_19 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 344.0
CMS2_k127_3240111_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 1.657e-218 696.0
CMS2_k127_3240111_20 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 336.0
CMS2_k127_3240111_21 PFAM ABC transporter related K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 325.0
CMS2_k127_3240111_22 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 340.0
CMS2_k127_3240111_23 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 291.0
CMS2_k127_3240111_24 epimerase dehydratase K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 292.0
CMS2_k127_3240111_25 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001338 285.0
CMS2_k127_3240111_26 PFAM GHMP kinase K01597 - 4.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002517 279.0
CMS2_k127_3240111_27 response regulator, receiver K02479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001235 266.0
CMS2_k127_3240111_28 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002347 267.0
CMS2_k127_3240111_29 Esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.00000000000000000000000000000000000000000000000000000000000000000000004222 256.0
CMS2_k127_3240111_3 Aldehyde dehydrogenase family K00128 - 1.2.1.3 4.736e-203 644.0
CMS2_k127_3240111_30 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006054 247.0
CMS2_k127_3240111_31 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000006686 228.0
CMS2_k127_3240111_32 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000002322 222.0
CMS2_k127_3240111_33 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000001691 219.0
CMS2_k127_3240111_34 - - - - 0.0000000000000000000000000000000000000000000000000000000004219 211.0
CMS2_k127_3240111_35 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.00000000000000000000000000000000000000000000000009231 189.0
CMS2_k127_3240111_36 PFAM GCN5-related N-acetyltransferase K03824 - - 0.000000000000000000000000000000000000000000000006708 176.0
CMS2_k127_3240111_37 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000000006904 174.0
CMS2_k127_3240111_38 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000005191 165.0
CMS2_k127_3240111_39 PFAM Formylglycine-generating sulfatase enzyme K18912,K20333 - 1.14.99.50 0.0000000000000000000000000000000000000106 160.0
CMS2_k127_3240111_4 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 612.0
CMS2_k127_3240111_40 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000002441 146.0
CMS2_k127_3240111_41 Ntpase (Nacht family) K12132 - 2.7.11.1 0.00000000000000000000000000000000004223 156.0
CMS2_k127_3240111_42 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000006459 147.0
CMS2_k127_3240111_43 regulation of response to stimulus - - - 0.00000000000000000000000008844 119.0
CMS2_k127_3240111_44 PFAM Protein kinase domain - - - 0.00000000000000000000443 110.0
CMS2_k127_3240111_45 sequence-specific DNA binding K15539 - - 0.00000000000000000001396 100.0
CMS2_k127_3240111_46 - - - - 0.00000000000000000003104 95.0
CMS2_k127_3240111_48 methylated DNA-protein cysteine methyltransferase K07443 - - 0.0000000000000000305 86.0
CMS2_k127_3240111_49 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000005557 78.0
CMS2_k127_3240111_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 597.0
CMS2_k127_3240111_50 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000358 75.0
CMS2_k127_3240111_53 deoxyhypusine monooxygenase activity - - - 0.00000007353 64.0
CMS2_k127_3240111_54 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000001268 55.0
CMS2_k127_3240111_6 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 593.0
CMS2_k127_3240111_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 595.0
CMS2_k127_3240111_8 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 580.0
CMS2_k127_3240111_9 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 525.0
CMS2_k127_3309755_0 Stage II sporulation K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000732 350.0
CMS2_k127_3309755_1 TIGRFAM DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000006439 200.0
CMS2_k127_3309755_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000005004 147.0
CMS2_k127_3343397_0 Required for chromosome condensation and partitioning K03529 - - 5.918e-291 933.0
CMS2_k127_3343397_1 beta-galactosidase activity K01190 - 3.2.1.23 1.409e-255 823.0
CMS2_k127_3343397_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 383.0
CMS2_k127_3343397_11 ROK family K00845,K00847 - 2.7.1.2,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 372.0
CMS2_k127_3343397_12 Belongs to the peptidase S51 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 364.0
CMS2_k127_3343397_13 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 316.0
CMS2_k127_3343397_14 Threonyl alanyl tRNA synthetase SAD K01872,K07050 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 303.0
CMS2_k127_3343397_15 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 298.0
CMS2_k127_3343397_16 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003849 282.0
CMS2_k127_3343397_17 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001532 256.0
CMS2_k127_3343397_18 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000007946 222.0
CMS2_k127_3343397_19 TIGRFAM threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000009641 218.0
CMS2_k127_3343397_2 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.522e-226 709.0
CMS2_k127_3343397_20 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000007936 189.0
CMS2_k127_3343397_21 Domain of unknown function - - - 0.000000000000000000000000000000000000000000000004162 181.0
CMS2_k127_3343397_22 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000004129 180.0
CMS2_k127_3343397_23 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000000000000001585 175.0
CMS2_k127_3343397_24 F420H(2)-dependent quinone reductase - - - 0.000000000000000000000000000000000000000008406 160.0
CMS2_k127_3343397_25 Thrombospondin type 3 repeat - - - 0.000000000000000000000000000000000000042 166.0
CMS2_k127_3343397_26 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000046 121.0
CMS2_k127_3343397_27 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.0000000000000000000000000009493 124.0
CMS2_k127_3343397_28 AAA domain K02282 - - 0.000000000000000000000000005856 114.0
CMS2_k127_3343397_29 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000222 105.0
CMS2_k127_3343397_3 Hydantoinase/oxoprolinase N-terminal region K01469,K01473 - 3.5.2.14,3.5.2.9 1.999e-220 702.0
CMS2_k127_3343397_30 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) K07069 - - 0.00000000000000000001582 93.0
CMS2_k127_3343397_31 Nucleic-acid-binding protein containing Zn-ribbon domain (DUF2082) K07069 - - 0.00000000000000000002984 92.0
CMS2_k127_3343397_32 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000007143 92.0
CMS2_k127_3343397_33 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000178 90.0
CMS2_k127_3343397_34 COG2010 Cytochrome c, mono- and diheme variants K02305 - - 0.000000000000001183 81.0
CMS2_k127_3343397_35 PspC domain - - - 0.00000000003725 65.0
CMS2_k127_3343397_36 Peptidase of plants and bacteria - - - 0.000000001642 70.0
CMS2_k127_3343397_37 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.00000294 52.0
CMS2_k127_3343397_38 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.000003167 60.0
CMS2_k127_3343397_39 Alpha/beta hydrolase family - - - 0.00001071 58.0
CMS2_k127_3343397_4 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.268e-197 628.0
CMS2_k127_3343397_40 Peptidase C39 family K06021,K13409,K20344 - 3.6.3.27 0.0004837 51.0
CMS2_k127_3343397_5 CoA binding domain K01905,K22224 - 6.2.1.13 1.959e-196 634.0
CMS2_k127_3343397_6 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 529.0
CMS2_k127_3343397_7 Belongs to the glycosyl hydrolase 31 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 505.0
CMS2_k127_3343397_8 DNA methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 397.0
CMS2_k127_3343397_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 391.0
CMS2_k127_3361802_0 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 2.362e-282 895.0
CMS2_k127_3361802_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.992e-237 748.0
CMS2_k127_3361802_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000001377 233.0
CMS2_k127_3361802_11 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000001929 208.0
CMS2_k127_3361802_12 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000004639 196.0
CMS2_k127_3361802_13 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000001049 171.0
CMS2_k127_3361802_14 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000005702 173.0
CMS2_k127_3361802_15 acetyltransferase - - - 0.0000000000000000000000000000000000000002677 156.0
CMS2_k127_3361802_16 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000005566 137.0
CMS2_k127_3361802_17 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000002691 140.0
CMS2_k127_3361802_18 Protein of unknown function (DUF448) K07742 - - 0.000000000000000000000000000002472 123.0
CMS2_k127_3361802_19 - - - - 0.00000000000000000000000000001446 127.0
CMS2_k127_3361802_2 Participates in both transcription termination and antitermination K02600 - - 8.176e-195 626.0
CMS2_k127_3361802_20 PFAM membrane protein of K08972 - - 0.0000000000000000000000000004197 117.0
CMS2_k127_3361802_21 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000155 115.0
CMS2_k127_3361802_22 - - - - 0.000000000000000001244 88.0
CMS2_k127_3361802_23 Scp-like extracellular - - - 0.00000000111 69.0
CMS2_k127_3361802_24 Rdx family K07401 - - 0.000000007235 59.0
CMS2_k127_3361802_25 BlaR1 peptidase M56 - - - 0.00000002656 66.0
CMS2_k127_3361802_26 peptidase inhibitor activity K01406 - 3.4.24.40 0.000003369 60.0
CMS2_k127_3361802_27 - - - - 0.000928 50.0
CMS2_k127_3361802_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 484.0
CMS2_k127_3361802_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 449.0
CMS2_k127_3361802_5 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 297.0
CMS2_k127_3361802_6 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 295.0
CMS2_k127_3361802_7 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008489 274.0
CMS2_k127_3361802_8 phosphatidylinositol metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002334 256.0
CMS2_k127_3361802_9 Trypsin-like peptidase domain K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000008563 251.0
CMS2_k127_3391571_0 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 434.0
CMS2_k127_3391571_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 371.0
CMS2_k127_3391571_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000009064 219.0
CMS2_k127_3504358_0 PFAM NADH flavin oxidoreductase NADH oxidase K00317 - 1.5.8.1,1.5.8.2 9.694e-299 930.0
CMS2_k127_3504358_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 475.0
CMS2_k127_3504358_2 ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 426.0
CMS2_k127_3504358_3 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 427.0
CMS2_k127_3504358_4 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 407.0
CMS2_k127_3504358_5 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000586 224.0
CMS2_k127_3504358_6 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000004623 211.0
CMS2_k127_3504358_7 integrase family - - - 0.000222 48.0
CMS2_k127_3548934_0 Belongs to the formate--tetrahydrofolate ligase family K00288,K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 4.557e-304 942.0
CMS2_k127_3548934_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 566.0
CMS2_k127_3548934_2 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 441.0
CMS2_k127_3548934_3 serine-type peptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001091 254.0
CMS2_k127_3548934_4 - - - - 0.00000000000000000000000000000000001549 146.0
CMS2_k127_3553915_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 316.0
CMS2_k127_3553915_1 Homeodomain-like domain - - - 0.00000000000000000000000000000000000000000000006842 175.0
CMS2_k127_3553915_2 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986,K07451 - 2.7.7.49 0.0000000000000000000000002987 108.0
CMS2_k127_3553915_3 transposition, DNA-mediated K02342,K07480 - 2.7.7.7 0.000000000000000008798 87.0
CMS2_k127_3620488_0 COG1472 Beta-glucosidase-related glycosidases K05349 - 3.2.1.21 5.827e-200 642.0
CMS2_k127_3620488_1 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 318.0
CMS2_k127_3620488_2 CoA-transferase activity K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000818 178.0
CMS2_k127_3652773_0 Multicopper oxidase - - - 0.0 1317.0
CMS2_k127_3728990_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009558 366.0
CMS2_k127_3728990_1 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 331.0
CMS2_k127_3728990_2 PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000002478 239.0
CMS2_k127_3728990_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000003424 179.0
CMS2_k127_3728990_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0001171 48.0
CMS2_k127_3733199_0 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.0 1279.0
CMS2_k127_3733199_1 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 5.271e-262 823.0
CMS2_k127_3733199_10 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000001605 111.0
CMS2_k127_3733199_11 META domain - - - 0.000000000000001044 82.0
CMS2_k127_3733199_12 Response regulator receiver domain - - - 0.00005853 54.0
CMS2_k127_3733199_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 459.0
CMS2_k127_3733199_3 Thermophilic metalloprotease (M29) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 417.0
CMS2_k127_3733199_4 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 368.0
CMS2_k127_3733199_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000004701 232.0
CMS2_k127_3733199_6 PFAM DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000000000002651 182.0
CMS2_k127_3733199_7 dihydroorotate dehydrogenase activity K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000552 165.0
CMS2_k127_3733199_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000005356 154.0
CMS2_k127_3733199_9 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000004206 109.0
CMS2_k127_374346_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1288.0
CMS2_k127_374346_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1189.0
CMS2_k127_374346_10 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 1.163e-221 702.0
CMS2_k127_374346_100 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000002576 140.0
CMS2_k127_374346_101 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000002766 137.0
CMS2_k127_374346_102 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000002993 140.0
CMS2_k127_374346_103 Methyltransferase type 11 - - - 0.00000000000000000000000000003789 126.0
CMS2_k127_374346_105 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 2.1.1.63 0.000000000000000000000000001725 119.0
CMS2_k127_374346_106 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000001144 111.0
CMS2_k127_374346_107 chromosome segregation K03497 - - 0.00000000000000000000000003196 118.0
CMS2_k127_374346_108 protein possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000007154 113.0
CMS2_k127_374346_109 sh3 domain protein K01227,K03642 - 3.2.1.96 0.00000000000000000000000007617 123.0
CMS2_k127_374346_11 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.748e-221 691.0
CMS2_k127_374346_110 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001212 107.0
CMS2_k127_374346_113 arsR family K21903 - - 0.000000000000000000001608 96.0
CMS2_k127_374346_114 PFAM helix-turn-helix- domain containing protein, AraC type K13653 - - 0.00000000000000000000204 99.0
CMS2_k127_374346_115 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.000000000000000000002649 99.0
CMS2_k127_374346_116 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000002805 94.0
CMS2_k127_374346_117 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000001275 94.0
CMS2_k127_374346_118 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000002705 96.0
CMS2_k127_374346_119 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000002122 86.0
CMS2_k127_374346_12 Endoribonuclease that initiates mRNA decay K18682 - - 7.409e-210 663.0
CMS2_k127_374346_120 PFAM Forkhead-associated protein - - - 0.00000000000000002618 89.0
CMS2_k127_374346_121 Ribosomal protein L30 K02907 - - 0.0000000000000003562 80.0
CMS2_k127_374346_122 PFAM DinB family protein - - - 0.000000000000001112 84.0
CMS2_k127_374346_123 Domain of unknown function (DUF333) K14475 - - 0.00000000000005178 82.0
CMS2_k127_374346_126 4Fe-4S binding domain - - - 0.0000000000181 67.0
CMS2_k127_374346_127 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000002951 63.0
CMS2_k127_374346_128 Protein of unknown function (DUF3592) - - - 0.00000000005968 71.0
CMS2_k127_374346_129 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000003967 63.0
CMS2_k127_374346_13 Beta-eliminating lyase - - - 3.474e-205 647.0
CMS2_k127_374346_130 transcriptional regulator K07736 - - 0.0000000004903 67.0
CMS2_k127_374346_131 DinB superfamily - - - 0.000000007313 64.0
CMS2_k127_374346_132 Protein of unknown function (DUF1572) - - - 0.000000007842 63.0
CMS2_k127_374346_133 gluconokinase activity - - - 0.000000008022 64.0
CMS2_k127_374346_134 COG1575 1,4-dihydroxy-2-naphthoate octaprenyltransferase K02548 - 2.5.1.74 0.00000007757 63.0
CMS2_k127_374346_135 spore coat K01790 - 5.1.3.13 0.0000002742 57.0
CMS2_k127_374346_137 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.0002535 50.0
CMS2_k127_374346_138 - - - - 0.0003225 49.0
CMS2_k127_374346_14 nitronate monooxygenase activity - - - 2.501e-200 638.0
CMS2_k127_374346_15 Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 627.0
CMS2_k127_374346_16 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 610.0
CMS2_k127_374346_17 TIGRFAM MazG family protein K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 560.0
CMS2_k127_374346_18 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 538.0
CMS2_k127_374346_19 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008399 550.0
CMS2_k127_374346_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1172.0
CMS2_k127_374346_20 PFAM ABC transporter related K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 535.0
CMS2_k127_374346_21 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 535.0
CMS2_k127_374346_22 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 544.0
CMS2_k127_374346_23 PFAM ABC transporter transmembrane region K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 540.0
CMS2_k127_374346_24 Beta-lactamase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 494.0
CMS2_k127_374346_25 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 490.0
CMS2_k127_374346_26 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 484.0
CMS2_k127_374346_27 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 473.0
CMS2_k127_374346_28 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 452.0
CMS2_k127_374346_29 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 428.0
CMS2_k127_374346_3 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.606e-314 975.0
CMS2_k127_374346_30 PFAM PfkB domain protein K00856 - 2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 411.0
CMS2_k127_374346_31 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 400.0
CMS2_k127_374346_32 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 395.0
CMS2_k127_374346_33 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 388.0
CMS2_k127_374346_34 dimethylargininase activity K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 388.0
CMS2_k127_374346_35 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 385.0
CMS2_k127_374346_36 TIGRFAM phosphate binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 376.0
CMS2_k127_374346_37 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 366.0
CMS2_k127_374346_38 WD40 domain protein beta Propeller K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 373.0
CMS2_k127_374346_39 Mechanosensitive ion channel K16053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 349.0
CMS2_k127_374346_4 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 4.224e-293 917.0
CMS2_k127_374346_40 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 338.0
CMS2_k127_374346_41 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 331.0
CMS2_k127_374346_42 heme binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 334.0
CMS2_k127_374346_43 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007666 339.0
CMS2_k127_374346_44 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 327.0
CMS2_k127_374346_45 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 321.0
CMS2_k127_374346_46 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 308.0
CMS2_k127_374346_47 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 309.0
CMS2_k127_374346_48 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 312.0
CMS2_k127_374346_49 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 308.0
CMS2_k127_374346_5 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 5.993e-290 907.0
CMS2_k127_374346_50 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 300.0
CMS2_k127_374346_51 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 291.0
CMS2_k127_374346_52 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 295.0
CMS2_k127_374346_53 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000354 274.0
CMS2_k127_374346_54 Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003973 289.0
CMS2_k127_374346_55 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000186 280.0
CMS2_k127_374346_56 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000008444 265.0
CMS2_k127_374346_57 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006219 261.0
CMS2_k127_374346_58 Baseplate J-like protein K01218 - 3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000001191 264.0
CMS2_k127_374346_59 DNA binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000001499 241.0
CMS2_k127_374346_6 PBP superfamily domain K03750,K07219 - 2.10.1.1 6.784e-275 859.0
CMS2_k127_374346_60 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000005955 235.0
CMS2_k127_374346_61 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000001253 225.0
CMS2_k127_374346_62 Domain of unknown function (DUF4380) - - - 0.000000000000000000000000000000000000000000000000000000000000009075 226.0
CMS2_k127_374346_63 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000004656 224.0
CMS2_k127_374346_64 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000005426 215.0
CMS2_k127_374346_65 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000168 212.0
CMS2_k127_374346_66 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000002967 210.0
CMS2_k127_374346_67 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000009335 210.0
CMS2_k127_374346_68 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000001764 229.0
CMS2_k127_374346_69 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000000000009915 211.0
CMS2_k127_374346_7 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 2.622e-252 806.0
CMS2_k127_374346_70 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000003679 201.0
CMS2_k127_374346_71 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000000000000000000004272 203.0
CMS2_k127_374346_72 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000001015 206.0
CMS2_k127_374346_73 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000103 199.0
CMS2_k127_374346_74 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000000000000000000001102 213.0
CMS2_k127_374346_75 DNA mismatch repair protein MutT - - - 0.00000000000000000000000000000000000000000000000000000001143 204.0
CMS2_k127_374346_76 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001256 202.0
CMS2_k127_374346_77 metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000004609 198.0
CMS2_k127_374346_78 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000008801 199.0
CMS2_k127_374346_79 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000000000000000000000000000000000009939 198.0
CMS2_k127_374346_8 cyclic 2,3-diphosphoglycerate synthetase activity - - - 2.909e-237 738.0
CMS2_k127_374346_80 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000001705 192.0
CMS2_k127_374346_81 Inner membrane component domain - - - 0.000000000000000000000000000000000000000000000000000777 185.0
CMS2_k127_374346_82 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.000000000000000000000000000000000000000000000000001889 189.0
CMS2_k127_374346_83 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000000000000000000003094 190.0
CMS2_k127_374346_84 Aminoacyl-tRNA editing domain K03976 - - 0.00000000000000000000000000000000000000000000000006061 184.0
CMS2_k127_374346_85 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000008292 191.0
CMS2_k127_374346_86 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000006494 181.0
CMS2_k127_374346_87 Protein of unknown function (DUF1461) - - - 0.000000000000000000000000000000000000000000000524 174.0
CMS2_k127_374346_88 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000001824 168.0
CMS2_k127_374346_89 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000004301 167.0
CMS2_k127_374346_9 cadmium-exporting ATPase K01534 - 3.6.3.3,3.6.3.5 6.939e-222 707.0
CMS2_k127_374346_90 - - - - 0.00000000000000000000000000000000000000000004662 166.0
CMS2_k127_374346_91 PFAM Diacylglycerol kinase catalytic - - - 0.000000000000000000000000000000000000000002032 168.0
CMS2_k127_374346_92 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000003101 157.0
CMS2_k127_374346_93 PFAM Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000001255 165.0
CMS2_k127_374346_94 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000002834 155.0
CMS2_k127_374346_95 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000002478 147.0
CMS2_k127_374346_96 Glycosyl hydrolases family 25 K07273 - - 0.00000000000000000000000000000000000005427 164.0
CMS2_k127_374346_97 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008176,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0034708,GO:0036265,GO:0040007,GO:0043170,GO:0043412,GO:0043414,GO:0043527,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0106004,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1990234 2.1.1.33 0.000000000000000000000000000000000001248 147.0
CMS2_k127_374346_98 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000001635 140.0
CMS2_k127_374346_99 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000001898 147.0
CMS2_k127_3801160_0 Large extracellular alpha-helical protein - - - 0.0000000000000000000001974 109.0
CMS2_k127_3832465_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000003115 263.0
CMS2_k127_3832465_1 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000001874 124.0
CMS2_k127_3832465_2 HupE / UreJ protein K03192 - - 0.000000000002877 68.0
CMS2_k127_396256_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 5.378e-315 979.0
CMS2_k127_396256_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 2.158e-282 884.0
CMS2_k127_396256_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000005303 223.0
CMS2_k127_396256_11 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.0000000000000000000000000000000000000000000000001013 185.0
CMS2_k127_396256_12 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000000000000000000000005021 165.0
CMS2_k127_396256_13 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000001073 144.0
CMS2_k127_396256_14 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000005654 138.0
CMS2_k127_396256_15 UPF0316 protein - - - 0.000000000000000000000000001202 121.0
CMS2_k127_396256_16 Histidine kinase K01768,K12132 - 2.7.11.1,4.6.1.1 0.00000000000000001587 86.0
CMS2_k127_396256_19 TIGRFAM Lysine biosynthesis protein LysW K05826 - - 0.00009953 48.0
CMS2_k127_396256_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 3.944e-199 639.0
CMS2_k127_396256_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 583.0
CMS2_k127_396256_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 505.0
CMS2_k127_396256_5 peptidase M29 aminopeptidase II K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 423.0
CMS2_k127_396256_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 327.0
CMS2_k127_396256_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 298.0
CMS2_k127_396256_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002756 280.0
CMS2_k127_396256_9 PFAM Translin K07477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000163 241.0
CMS2_k127_4075982_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1059.0
CMS2_k127_4075982_1 Pyridoxal-phosphate dependent enzyme - - - 5.182e-250 777.0
CMS2_k127_4075982_10 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 475.0
CMS2_k127_4075982_11 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 436.0
CMS2_k127_4075982_12 Amidohydrolase family K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 424.0
CMS2_k127_4075982_13 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 416.0
CMS2_k127_4075982_14 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 412.0
CMS2_k127_4075982_15 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 376.0
CMS2_k127_4075982_16 Nucleotidyl transferase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 351.0
CMS2_k127_4075982_17 PFAM UbiA prenyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 342.0
CMS2_k127_4075982_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 326.0
CMS2_k127_4075982_19 TIGRFAM mevalonate kinase K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 296.0
CMS2_k127_4075982_2 Selenocysteine-specific translation elongation factor K03833 - - 1.853e-228 723.0
CMS2_k127_4075982_20 Proton-conducting membrane transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003727 283.0
CMS2_k127_4075982_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005689 277.0
CMS2_k127_4075982_22 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000236 244.0
CMS2_k127_4075982_23 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000005143 238.0
CMS2_k127_4075982_24 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006222 238.0
CMS2_k127_4075982_26 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000242 232.0
CMS2_k127_4075982_27 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000004418 198.0
CMS2_k127_4075982_28 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000002644 188.0
CMS2_k127_4075982_29 Transcription elongation factor, N-terminal K03624 - - 0.000000000000000000000000000000000000000007585 158.0
CMS2_k127_4075982_3 Amidohydrolase family - - - 9.89e-219 686.0
CMS2_k127_4075982_30 PFAM CoA-binding domain protein K06929 - - 0.000000000000000000000000000000000002137 144.0
CMS2_k127_4075982_31 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000001439 136.0
CMS2_k127_4075982_32 integral membrane protein - - - 0.00000000000000000000000000000004479 140.0
CMS2_k127_4075982_33 Protein of unknown function (DUF952) - - - 0.0000000000000000000000000007329 115.0
CMS2_k127_4075982_35 Helix-turn-helix K07729 - - 0.0000000000000000001343 90.0
CMS2_k127_4075982_36 Belongs to the UPF0109 family K06960 - - 0.0000000000000000002748 89.0
CMS2_k127_4075982_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 580.0
CMS2_k127_4075982_5 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 573.0
CMS2_k127_4075982_6 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 564.0
CMS2_k127_4075982_7 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 516.0
CMS2_k127_4075982_8 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 487.0
CMS2_k127_4075982_9 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 466.0
CMS2_k127_4077512_0 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000003782 175.0
CMS2_k127_4077512_1 TfoX N-terminal domain - - - 0.0000000000000000000000009309 108.0
CMS2_k127_4077512_2 PFAM Transglycosylase SLT domain K08309 - - 0.00000000000002116 82.0
CMS2_k127_4101897_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 1.351e-196 621.0
CMS2_k127_4101897_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 501.0
CMS2_k127_4101897_10 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000001634 220.0
CMS2_k127_4101897_11 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000001438 184.0
CMS2_k127_4101897_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000001657 100.0
CMS2_k127_4101897_13 SMART PAS domain containing protein - - - 0.0000000000000000008096 94.0
CMS2_k127_4101897_16 Zinc finger domain - - - 0.00000000000009874 83.0
CMS2_k127_4101897_17 ubiE/COQ5 methyltransferase family - - - 0.0000000001521 70.0
CMS2_k127_4101897_18 Endonuclease exonuclease phosphatase. Source PGD - - - 0.00004065 55.0
CMS2_k127_4101897_19 - - - - 0.00006513 47.0
CMS2_k127_4101897_2 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 415.0
CMS2_k127_4101897_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 380.0
CMS2_k127_4101897_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 336.0
CMS2_k127_4101897_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 331.0
CMS2_k127_4101897_6 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006617 283.0
CMS2_k127_4101897_7 TRANSCRIPTIONal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005316 277.0
CMS2_k127_4101897_8 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005561 262.0
CMS2_k127_4101897_9 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003176 278.0
CMS2_k127_4142023_0 Elongator protein 3, MiaB family, Radical SAM - - - 9.84e-260 816.0
CMS2_k127_4142023_1 PFAM SMC domain protein K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 617.0
CMS2_k127_4142023_10 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000001739 257.0
CMS2_k127_4142023_11 helix_turn _helix lactose operon repressor K02529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001203 257.0
CMS2_k127_4142023_12 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.000000000000000000000000000000000000000000000000000000000000000005652 236.0
CMS2_k127_4142023_13 OsmC-like protein K09136 - - 0.000000000000000000000000000000000000000000000000000000004642 201.0
CMS2_k127_4142023_14 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000001137 212.0
CMS2_k127_4142023_15 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000001855 182.0
CMS2_k127_4142023_16 glyoxalase III activity K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000002449 176.0
CMS2_k127_4142023_17 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000001045 166.0
CMS2_k127_4142023_18 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K06019 - 3.6.1.1 0.0000000000000000000000000000000000000000006835 165.0
CMS2_k127_4142023_19 Bacterial regulatory protein, arsR family - - - 0.0000000000000000000000000000000000001719 143.0
CMS2_k127_4142023_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 454.0
CMS2_k127_4142023_20 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000005347 144.0
CMS2_k127_4142023_21 Zn peptidase - - - 0.000000000000000000000000000000000006157 158.0
CMS2_k127_4142023_22 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000001265 138.0
CMS2_k127_4142023_23 PFAM Rhodanese domain protein - - - 0.0000000000000000000000000000000003999 136.0
CMS2_k127_4142023_24 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000004969 131.0
CMS2_k127_4142023_25 menaquinone-dependent protoporphyrinogen oxidase activity K00230 - 1.3.5.3 0.000000000000000000000000002976 117.0
CMS2_k127_4142023_26 - - - - 0.00000000000000000000000003736 110.0
CMS2_k127_4142023_27 Putative Fe-S cluster - - - 0.0000000000000000000000008071 110.0
CMS2_k127_4142023_28 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase K07777 - 2.7.13.3 0.00000000000000001956 97.0
CMS2_k127_4142023_29 Transcriptional regulator K07693 - - 0.0000000000001871 80.0
CMS2_k127_4142023_3 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 422.0
CMS2_k127_4142023_30 Domain of unknown function (DUF4332) - - - 0.00000000001417 74.0
CMS2_k127_4142023_31 N-terminal 7TM region of histidine kinase - - - 0.0000001049 65.0
CMS2_k127_4142023_32 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000002783 63.0
CMS2_k127_4142023_33 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000001084 56.0
CMS2_k127_4142023_34 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000166 55.0
CMS2_k127_4142023_35 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088 - - 0.0003691 48.0
CMS2_k127_4142023_4 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 421.0
CMS2_k127_4142023_5 PFAM major facilitator superfamily MFS_1 K08161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 404.0
CMS2_k127_4142023_6 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 387.0
CMS2_k127_4142023_7 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 343.0
CMS2_k127_4142023_8 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 333.0
CMS2_k127_4142023_9 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008154 285.0
CMS2_k127_4149039_0 ATP synthesis coupled electron transport K00336 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 1.973e-298 938.0
CMS2_k127_4149039_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 2.709e-208 658.0
CMS2_k127_4149039_10 negative regulation of transcription, DNA-templated K10947 - - 0.00000000000000000000000000000001172 131.0
CMS2_k127_4149039_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000003863 124.0
CMS2_k127_4149039_12 - - - - 0.00000000000000000000000000005172 124.0
CMS2_k127_4149039_13 Yip1 domain - - - 0.0000000000000000001349 97.0
CMS2_k127_4149039_14 alcohol dehydrogenase - - - 0.00000001874 66.0
CMS2_k127_4149039_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 583.0
CMS2_k127_4149039_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 522.0
CMS2_k127_4149039_4 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K12137 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015672,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0030964,GO:0031224,GO:0031226,GO:0032991,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0051179,GO:0051234,GO:0055085,GO:0070469,GO:0070470,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1902600,GO:1990204 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 514.0
CMS2_k127_4149039_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 424.0
CMS2_k127_4149039_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 344.0
CMS2_k127_4149039_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002169 256.0
CMS2_k127_4149039_8 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.0000000000000000000000000000000000000000000000000000000000000005918 226.0
CMS2_k127_4149039_9 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000001797 153.0
CMS2_k127_4151602_0 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000008152 213.0
CMS2_k127_4151602_1 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.0000000000000000000000000000000000001961 143.0
CMS2_k127_4151602_2 PFAM Protein kinase domain K08884 - 2.7.11.1 0.000243 52.0
CMS2_k127_4160961_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 376.0
CMS2_k127_4160961_1 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000003001 174.0
CMS2_k127_4160961_2 MazG nucleotide pyrophosphohydrolase domain - - - 0.0000000000000000004316 90.0
CMS2_k127_4170461_0 Glycosyltransferase family 28 N-terminal domain K05841 - 2.4.1.173 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 526.0
CMS2_k127_4170461_2 Cyclic nucleotide-monophosphate binding domain K21564 - - 0.000000000000000000000000000000000000000000000005629 182.0
CMS2_k127_4170461_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000000009838 171.0
CMS2_k127_4170461_4 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000000000000171 160.0
CMS2_k127_4170461_5 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000000000002939 150.0
CMS2_k127_4170461_6 Thioesterase superfamily - - - 0.00000000000000000000000000000000000007935 146.0
CMS2_k127_4170461_7 efflux transmembrane transporter activity K02004 - - 0.0000021 59.0
CMS2_k127_4209878_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1112.0
CMS2_k127_4209878_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 1.553e-232 730.0
CMS2_k127_4209878_10 Biotin-requiring enzyme - - - 0.000000000000000000001502 99.0
CMS2_k127_4209878_11 Protein of unknown function (DUF2877) - - - 0.000000000000000006714 95.0
CMS2_k127_4209878_12 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000005143 84.0
CMS2_k127_4209878_2 Protein of unknown function (DUF1116) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 576.0
CMS2_k127_4209878_3 oxaloacetate decarboxylase activity K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 511.0
CMS2_k127_4209878_4 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 464.0
CMS2_k127_4209878_5 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 338.0
CMS2_k127_4209878_6 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 304.0
CMS2_k127_4209878_7 xanthine dehydrogenase activity K03519,K19818 - 1.2.5.3,1.5.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 294.0
CMS2_k127_4209878_8 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000001611 232.0
CMS2_k127_4209878_9 PFAM NmrA family protein - - - 0.000000000000000000000000000000000000000003276 163.0
CMS2_k127_4219263_0 intracellular signal transduction - - - 3.027e-296 943.0
CMS2_k127_4219263_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 355.0
CMS2_k127_4219263_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 307.0
CMS2_k127_4219263_3 TIGRFAM conserved repeat domain - - - 0.000000000000000000000000000000000000000000000000000000000000001003 249.0
CMS2_k127_4219263_4 Domain of unknown function DUF11 - - - 0.00000000000000000000000000000000000000000000003393 196.0
CMS2_k127_4256466_0 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 449.0
CMS2_k127_4256466_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 414.0
CMS2_k127_4256466_10 PFAM ABC-2 type transporter K01992 - - 0.00000000001338 76.0
CMS2_k127_4256466_11 PFAM ABC-2 type transporter K01992 - - 0.00000001083 67.0
CMS2_k127_4256466_2 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006648 396.0
CMS2_k127_4256466_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001376 273.0
CMS2_k127_4256466_4 PFAM ABC transporter related K01990,K16907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002008 269.0
CMS2_k127_4256466_5 Peptidase S9 prolyl oligopeptidase active site - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006144 277.0
CMS2_k127_4256466_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006867 263.0
CMS2_k127_4256466_7 tungstate ion transport K01990,K07705,K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000001397 236.0
CMS2_k127_4256466_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000003042 202.0
CMS2_k127_4256466_9 - - - - 0.00000000000000000000000000000000000001303 151.0
CMS2_k127_4305129_0 Binding-protein-dependent transport system inner membrane component K17316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 501.0
CMS2_k127_4305129_1 Binding-protein-dependent transport system inner membrane component K17317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 437.0
CMS2_k127_4305129_2 PFAM extracellular solute-binding protein family 1 K10117,K17315 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 323.0
CMS2_k127_4305129_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006798 293.0
CMS2_k127_4305129_4 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000001916 237.0
CMS2_k127_4305129_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000004628 232.0
CMS2_k127_4305129_6 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000000000000000000002275 121.0
CMS2_k127_4305129_7 - - - - 0.00000001079 64.0
CMS2_k127_4322967_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000009136 102.0
CMS2_k127_4322967_1 META domain K03668 - - 0.0000000000000002098 88.0
CMS2_k127_432665_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000003173 150.0
CMS2_k127_4328943_0 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 336.0
CMS2_k127_4329751_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1171.0
CMS2_k127_433783_0 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 332.0
CMS2_k127_433783_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 312.0
CMS2_k127_433783_2 rRNA (adenine-N6,N6-)-dimethyltransferase activity K00561,K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182,2.1.1.184 0.000000000000000000000000000000000000000000000000000000000000000001469 237.0
CMS2_k127_433783_3 Ferric reductase like transmembrane component - - - 0.000000000000000000000000000000000000000000000000000000000000009402 232.0
CMS2_k127_433783_4 Acyl-transferase - - - 0.0000000000000000000000000000000000000000000000000002734 195.0
CMS2_k127_433783_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000004406 181.0
CMS2_k127_433783_6 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000002991 166.0
CMS2_k127_433783_7 Phage tail sheath protein K06907 - - 0.0000000000526 64.0
CMS2_k127_4353732_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1244.0
CMS2_k127_4353732_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000004061 172.0
CMS2_k127_4353732_2 - - - - 0.0000000000000000002093 99.0
CMS2_k127_4353732_3 peroxiredoxin activity - - - 0.000000000005588 72.0
CMS2_k127_4353732_4 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000000008054 63.0
CMS2_k127_4400567_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 2.079e-237 748.0
CMS2_k127_4400567_1 Belongs to the N(4) N(6)-methyltransferase family K00571,K13581 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 504.0
CMS2_k127_4400567_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004473 237.0
CMS2_k127_4400567_11 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000002834 212.0
CMS2_k127_4400567_12 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000007129 214.0
CMS2_k127_4400567_13 Protein of unknown function (DUF3159) - - - 0.0000000000000000000000000000000000000000000000000000004542 201.0
CMS2_k127_4400567_14 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000006971 195.0
CMS2_k127_4400567_15 Phytanoyl-CoA dioxygenase - - - 0.000000000000000000000000000000000000000000000000001421 198.0
CMS2_k127_4400567_16 Putative membrane peptidase family (DUF2324) - - - 0.000000000000000000000000000000000000000000000000003896 194.0
CMS2_k127_4400567_18 ABC-2 family transporter protein - - - 0.0000000000000000000000000000000000000000001497 170.0
CMS2_k127_4400567_19 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000008362 164.0
CMS2_k127_4400567_2 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000955 444.0
CMS2_k127_4400567_20 Protein of unknown function (DUF1475) - - - 0.0000000000000000000000000000000000001437 145.0
CMS2_k127_4400567_21 TIGRFAM conserved - - - 0.000000000000000000000000000000000005289 143.0
CMS2_k127_4400567_22 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000008761 143.0
CMS2_k127_4400567_23 PFAM regulatory protein GntR HTH K07979 - - 0.000000000000000000000000007063 115.0
CMS2_k127_4400567_24 - - - - 0.00000000000000000000009556 104.0
CMS2_k127_4400567_25 Polysaccharide deacetylase - - - 0.000000000000000000009485 106.0
CMS2_k127_4400567_26 - - - - 0.0000000000000000005079 93.0
CMS2_k127_4400567_27 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07715 - - 0.0000000000000000431 91.0
CMS2_k127_4400567_28 - - - - 0.000000000000002219 83.0
CMS2_k127_4400567_29 - - - - 0.00000000000002042 84.0
CMS2_k127_4400567_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 423.0
CMS2_k127_4400567_31 Redoxin - - - 0.00000001402 57.0
CMS2_k127_4400567_4 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 369.0
CMS2_k127_4400567_5 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 361.0
CMS2_k127_4400567_6 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 349.0
CMS2_k127_4400567_7 PFAM Shikimate quinate 5-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 336.0
CMS2_k127_4400567_8 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000005143 256.0
CMS2_k127_4400567_9 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005382 242.0
CMS2_k127_445361_0 Aldo/keto reductase family K05882 - 1.1.1.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 462.0
CMS2_k127_445361_1 Restriction endonuclease K07448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 364.0
CMS2_k127_445361_2 PFAM oxidoreductase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 355.0
CMS2_k127_445361_3 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 337.0
CMS2_k127_445361_4 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 317.0
CMS2_k127_445361_5 Exopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001194 239.0
CMS2_k127_445361_6 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000003115 220.0
CMS2_k127_445361_7 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000001768 142.0
CMS2_k127_445361_8 Endonuclease containing a URI domain K07461 - - 0.0000000000000000000000000001983 119.0
CMS2_k127_445361_9 Involved in the tonB-independent uptake of proteins - - - 0.00000000008645 75.0
CMS2_k127_4454827_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 558.0
CMS2_k127_4454827_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 460.0
CMS2_k127_4454827_2 Fe-S oxidoreductases K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009496 413.0
CMS2_k127_4454827_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 397.0
CMS2_k127_4454827_4 protoporphyrinogen oxidase activity K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 376.0
CMS2_k127_4454827_5 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 334.0
CMS2_k127_4454827_6 glutamyl-tRNA reductase activity K02407,K02492 GO:0005575,GO:0005623,GO:0009288,GO:0042597,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0055040 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 304.0
CMS2_k127_4454827_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 297.0
CMS2_k127_4454827_8 Uroporphyrinogen-III synthase HemD K01719,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000003171 207.0
CMS2_k127_445569_0 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000156 194.0
CMS2_k127_445569_1 Transcriptional Coactivator p15 (PC4) - - - 0.000000000000000000000000001068 113.0
CMS2_k127_445569_2 - - - - 0.0000000000009037 73.0
CMS2_k127_4504147_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 9.378e-227 712.0
CMS2_k127_4504147_1 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 GO:0003674,GO:0003824,GO:0004335,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008108,GO:0008150,GO:0008152,GO:0008198,GO:0008270,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019200,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046835,GO:0046872,GO:0046914,GO:0070569,GO:0071704,GO:1901575 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 493.0
CMS2_k127_4504147_2 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 326.0
CMS2_k127_4504147_3 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000000000000000000000000000000001953 169.0
CMS2_k127_4504147_4 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.000000000000000000000001468 103.0
CMS2_k127_4504147_5 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000001986 78.0
CMS2_k127_4504147_6 HTH-like domain - - - 0.000009263 48.0
CMS2_k127_4517778_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1134.0
CMS2_k127_4517778_1 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 557.0
CMS2_k127_4517778_10 Rieske [2Fe-2S] domain K03886 - - 0.00000000000000000000000000112 119.0
CMS2_k127_4517778_11 Cytochrome b(C-terminal)/b6/petD K00412 - - 0.000000000000000000000004994 119.0
CMS2_k127_4517778_12 TIGRFAM phosphodiesterase, MJ0936 family K07095 - - 0.00000000000002646 78.0
CMS2_k127_4517778_13 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000001673 74.0
CMS2_k127_4517778_14 Protein of unknown function (DUF1549) - - - 0.00000001408 68.0
CMS2_k127_4517778_2 Helicase conserved C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 439.0
CMS2_k127_4517778_3 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 316.0
CMS2_k127_4517778_4 PFAM diacylglycerol kinase catalytic region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 295.0
CMS2_k127_4517778_5 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001243 289.0
CMS2_k127_4517778_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006435 253.0
CMS2_k127_4517778_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000002361 243.0
CMS2_k127_4517778_8 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000000000000000000000000000002016 233.0
CMS2_k127_4517778_9 DinB superfamily - - - 0.000000000000000000000000000000000000000000000009209 179.0
CMS2_k127_4529191_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 339.0
CMS2_k127_4529191_1 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 324.0
CMS2_k127_4529191_2 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000003022 227.0
CMS2_k127_4529191_3 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000001463 228.0
CMS2_k127_4529191_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000002203 136.0
CMS2_k127_4529191_5 ATPase-coupled phosphate ion transmembrane transporter activity K02036,K06857 - 3.6.3.27,3.6.3.55 0.000000000000000000000000000003286 124.0
CMS2_k127_454774_0 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 550.0
CMS2_k127_454774_1 PFAM Radical SAM domain protein K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 380.0
CMS2_k127_454774_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000007221 222.0
CMS2_k127_454774_3 PFAM Isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000002259 211.0
CMS2_k127_4551853_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 566.0
CMS2_k127_4551853_1 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 498.0
CMS2_k127_4551853_10 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000002834 207.0
CMS2_k127_4551853_11 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000002147 180.0
CMS2_k127_4551853_12 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.00000000000000000000000000000000000000008416 159.0
CMS2_k127_4551853_13 Nitroreductase family - - - 0.0000000000000000000000000000000000000004612 156.0
CMS2_k127_4551853_14 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000001313 139.0
CMS2_k127_4551853_15 2'-5' RNA ligase superfamily - - - 0.000000000000000000000000000004134 126.0
CMS2_k127_4551853_16 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000000000000000000003992 120.0
CMS2_k127_4551853_17 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000005314 79.0
CMS2_k127_4551853_2 SMART alpha amylase, catalytic sub domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 462.0
CMS2_k127_4551853_3 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 374.0
CMS2_k127_4551853_4 COG0477 Permeases of the major facilitator superfamily K08153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 338.0
CMS2_k127_4551853_5 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 324.0
CMS2_k127_4551853_6 Protein of unknown function (DUF1385) K09153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 310.0
CMS2_k127_4551853_7 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 306.0
CMS2_k127_4551853_8 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 293.0
CMS2_k127_4551853_9 PFAM NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000001713 220.0
CMS2_k127_4616445_0 Reverse transcriptase K00986 - 2.7.7.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 494.0
CMS2_k127_4616445_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000025 209.0
CMS2_k127_4676252_0 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 568.0
CMS2_k127_4676252_1 trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 524.0
CMS2_k127_4676252_2 Hydantoinaseoxoprolinase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 400.0
CMS2_k127_4676252_3 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000003445 280.0
CMS2_k127_4676252_4 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000002573 191.0
CMS2_k127_4676252_5 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000005934 107.0
CMS2_k127_4860636_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 4.171e-215 676.0
CMS2_k127_4860636_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004964 271.0
CMS2_k127_4860636_2 Transport permease protein K01992 - - 0.000000000000000000002295 107.0
CMS2_k127_4860636_3 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000008938 93.0
CMS2_k127_4956214_0 COG2801 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000002117 221.0
CMS2_k127_4956214_1 Transposase K07483 - - 0.0000000000000000000000000000006122 126.0
CMS2_k127_511038_0 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.00000000000000000000000000000000000000000000029 174.0
CMS2_k127_511038_1 chromosome segregation K03497 - - 0.00000000000000000000002811 109.0
CMS2_k127_5115891_0 guanyl-nucleotide exchange factor activity K06978,K12287,K21105 - 3.1.1.102 0.000000000000000000000000000000000000000000005453 180.0
CMS2_k127_5115891_1 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000004243 119.0
CMS2_k127_5115891_2 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000007445 97.0
CMS2_k127_5130463_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01668 - 4.1.99.2 4.464e-258 801.0
CMS2_k127_5130463_1 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 599.0
CMS2_k127_5130463_2 Glycoside hydrolase family 16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009071 455.0
CMS2_k127_5130463_3 Aldo Keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 335.0
CMS2_k127_5130463_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 334.0
CMS2_k127_5130463_5 PFAM Maf family protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002604 253.0
CMS2_k127_5130463_6 AI-2E family transporter - - - 0.0000000000000000000000004069 119.0
CMS2_k127_5130463_7 - - - - 0.000000000000000000001535 102.0
CMS2_k127_5137061_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 9.102e-215 677.0
CMS2_k127_5137061_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 5.604e-196 617.0
CMS2_k127_5137061_10 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000004945 223.0
CMS2_k127_5137061_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000001558 193.0
CMS2_k127_5137061_12 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000005677 182.0
CMS2_k127_5137061_13 PFAM phospholipid glycerol acyltransferase - - - 0.000000000000000000000000000000000000000000002547 177.0
CMS2_k127_5137061_14 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000002157 153.0
CMS2_k127_5137061_15 Acyl-transferase - - - 0.00000000000000000000000000000004719 137.0
CMS2_k127_5137061_16 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.0000000000000000000000000001829 120.0
CMS2_k127_5137061_17 Protein of unknown function (DUF3105) - - - 0.0000000000000000008032 94.0
CMS2_k127_5137061_19 protein secretion K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000001109 67.0
CMS2_k127_5137061_2 beta-galactosidase activity K01190,K17624 - 3.2.1.23,3.2.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 482.0
CMS2_k127_5137061_20 - - - - 0.000000001562 63.0
CMS2_k127_5137061_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 474.0
CMS2_k127_5137061_4 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 463.0
CMS2_k127_5137061_5 transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 385.0
CMS2_k127_5137061_6 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 361.0
CMS2_k127_5137061_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 353.0
CMS2_k127_5137061_8 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 313.0
CMS2_k127_5137061_9 PFAM YbbR family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000177 289.0
CMS2_k127_5148656_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K02574 - - 0.000000000000000000000002893 112.0
CMS2_k127_5166891_0 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 376.0
CMS2_k127_5173734_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 8.821e-222 710.0
CMS2_k127_5173734_1 PFAM glycosyl transferase, family 51 - - - 4.664e-202 664.0
CMS2_k127_5173734_10 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000235 291.0
CMS2_k127_5173734_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.000000000000000000000000000000000000000000000000000000000461 209.0
CMS2_k127_5173734_13 Mazg nucleotide pyrophosphohydrolase - - - 0.0000000000000000000000000009612 115.0
CMS2_k127_5173734_14 TIGRFAM C_GCAxxG_C_C family protein - - - 0.0000000000000000000001176 101.0
CMS2_k127_5173734_15 PFAM beta-lactamase domain protein - - - 0.00000000000000000003806 100.0
CMS2_k127_5173734_16 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000007111 97.0
CMS2_k127_5173734_17 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000003649 86.0
CMS2_k127_5173734_18 FtsZ-dependent cytokinesis K03975,K18292,K19302 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0051301,GO:0071944 3.6.1.27,4.1.3.25 0.00000000000001365 82.0
CMS2_k127_5173734_2 Serine dehydratase K01752 - 4.3.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 608.0
CMS2_k127_5173734_20 COG0456 Acetyltransferases K03789 - 2.3.1.128 0.0000000000001464 77.0
CMS2_k127_5173734_21 Alpha beta hydrolase - - - 0.0000002378 55.0
CMS2_k127_5173734_3 PFAM ABC transporter related K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006774 615.0
CMS2_k127_5173734_4 PFAM Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 417.0
CMS2_k127_5173734_5 NAD synthase K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 409.0
CMS2_k127_5173734_6 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 402.0
CMS2_k127_5173734_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 393.0
CMS2_k127_5173734_8 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 353.0
CMS2_k127_5173734_9 Radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 341.0
CMS2_k127_5215395_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 419.0
CMS2_k127_5225108_0 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 2.484e-269 838.0
CMS2_k127_5225108_1 Immune inhibitor A peptidase M6 - - - 4.583e-229 727.0
CMS2_k127_5225108_10 inositol 2-dehydrogenase activity K18431 - 2.7.7.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 419.0
CMS2_k127_5225108_11 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 396.0
CMS2_k127_5225108_12 Glycosyl transferase, family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 378.0
CMS2_k127_5225108_13 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 372.0
CMS2_k127_5225108_14 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 337.0
CMS2_k127_5225108_15 Enoyl-(Acyl carrier protein) reductase K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 336.0
CMS2_k127_5225108_16 Protein of unknown function DUF115 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 333.0
CMS2_k127_5225108_17 Glycosyl transferase, family 2 K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 324.0
CMS2_k127_5225108_18 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 332.0
CMS2_k127_5225108_19 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 306.0
CMS2_k127_5225108_2 teichoic acid transport K01990,K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 576.0
CMS2_k127_5225108_20 cytidylyl-transferase K00983 - 2.7.7.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 293.0
CMS2_k127_5225108_21 PFAM NAD-dependent epimerase dehydratase K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 295.0
CMS2_k127_5225108_22 3-deoxy-manno-octulosonate-8-phosphatase activity K00983,K03270 - 2.7.7.43,3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 286.0
CMS2_k127_5225108_23 Cytidylyltransferase K07257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000168 264.0
CMS2_k127_5225108_24 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004984 234.0
CMS2_k127_5225108_25 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000008373 205.0
CMS2_k127_5225108_26 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000001698 202.0
CMS2_k127_5225108_27 DNA-binding transcription factor activity K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000003189 178.0
CMS2_k127_5225108_29 -O-antigen - - - 0.0000000000000000000000000000000000325 151.0
CMS2_k127_5225108_3 PFAM Xylose isomerase domain protein TIM barrel K01654,K15898 - 2.5.1.56,2.5.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 561.0
CMS2_k127_5225108_30 Sulfotransferase domain - - - 0.000000000000000000000000000000002304 141.0
CMS2_k127_5225108_31 carbohydrate metabolic process - - - 0.000000000000000000000000005002 124.0
CMS2_k127_5225108_32 Protein of unknown function (DUF2726) - - - 0.000000006939 58.0
CMS2_k127_5225108_33 gas vesicle protein - - - 0.0003248 47.0
CMS2_k127_5225108_4 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 522.0
CMS2_k127_5225108_5 UDP-N-acetylglucosamine 2-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 523.0
CMS2_k127_5225108_6 SAF K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 498.0
CMS2_k127_5225108_7 4-phosphoerythronate dehydrogenase activity K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006651 492.0
CMS2_k127_5225108_8 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 473.0
CMS2_k127_5225108_9 lipid-A-disaccharide synthase activity K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 470.0
CMS2_k127_5241824_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.54e-302 937.0
CMS2_k127_5241824_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.342e-267 849.0
CMS2_k127_5241824_10 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 542.0
CMS2_k127_5241824_11 TIGRFAM cysteine desulfurase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 520.0
CMS2_k127_5241824_12 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 529.0
CMS2_k127_5241824_13 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 500.0
CMS2_k127_5241824_14 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 475.0
CMS2_k127_5241824_15 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 475.0
CMS2_k127_5241824_16 TIGRFAM tRNA-guanine transglycosylase, various specificities K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 469.0
CMS2_k127_5241824_17 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 447.0
CMS2_k127_5241824_18 Short-chain dehydrogenase reductase SDR K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 436.0
CMS2_k127_5241824_19 Aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 441.0
CMS2_k127_5241824_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.077e-246 769.0
CMS2_k127_5241824_20 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 421.0
CMS2_k127_5241824_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 421.0
CMS2_k127_5241824_22 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 416.0
CMS2_k127_5241824_23 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008354 409.0
CMS2_k127_5241824_24 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 384.0
CMS2_k127_5241824_25 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 348.0
CMS2_k127_5241824_26 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 355.0
CMS2_k127_5241824_27 carbohydrate binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 349.0
CMS2_k127_5241824_28 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 343.0
CMS2_k127_5241824_29 Alpha/beta hydrolase of unknown function (DUF1100) K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 346.0
CMS2_k127_5241824_3 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 7.004e-233 730.0
CMS2_k127_5241824_30 COG0477 Permeases of the major facilitator superfamily K08153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 333.0
CMS2_k127_5241824_31 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 308.0
CMS2_k127_5241824_32 PFAM glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 301.0
CMS2_k127_5241824_33 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 299.0
CMS2_k127_5241824_34 polysaccharide biosynthetic process K16694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 295.0
CMS2_k127_5241824_35 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000687 270.0
CMS2_k127_5241824_36 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009628 265.0
CMS2_k127_5241824_37 Chlorophyllase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000433 270.0
CMS2_k127_5241824_39 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000005843 243.0
CMS2_k127_5241824_4 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 2.857e-203 658.0
CMS2_k127_5241824_40 PFAM ribosomal RNA methyltransferase K18845 - 2.1.1.179 0.00000000000000000000000000000000000000000000000000000000000000000007146 239.0
CMS2_k127_5241824_41 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008854 240.0
CMS2_k127_5241824_42 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004459 228.0
CMS2_k127_5241824_43 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000006461 222.0
CMS2_k127_5241824_44 Class ii aldolase K01628,K03077,K18847 - 2.2.1.8,4.1.2.17,5.1.3.4 0.00000000000000000000000000000000000000000000000000000000001737 213.0
CMS2_k127_5241824_45 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000002631 228.0
CMS2_k127_5241824_46 PFAM peptidase M22 glycoprotease K14742 - - 0.0000000000000000000000000000000000000000000000000000000007536 209.0
CMS2_k127_5241824_47 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000000000000000104 207.0
CMS2_k127_5241824_48 Putative sensor - - - 0.00000000000000000000000000000000000000000000000000000059 203.0
CMS2_k127_5241824_49 Mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000002241 190.0
CMS2_k127_5241824_5 PFAM UDP-glucose GDP-mannose dehydrogenase K13015 - 1.1.1.136 2.65e-199 629.0
CMS2_k127_5241824_50 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000009304 177.0
CMS2_k127_5241824_51 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000000000003856 174.0
CMS2_k127_5241824_52 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000001431 179.0
CMS2_k127_5241824_53 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000007061 159.0
CMS2_k127_5241824_54 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000007531 150.0
CMS2_k127_5241824_55 NUDIX domain K08310 - 3.6.1.67 0.0000000000000000000000000000000000001366 146.0
CMS2_k127_5241824_56 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000007373 139.0
CMS2_k127_5241824_57 Thioesterase superfamily - - - 0.000000000000000000000000000000001974 134.0
CMS2_k127_5241824_58 PadR family transcriptional regulator K10947 - - 0.00000000000000000000000000000001333 132.0
CMS2_k127_5241824_59 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000002563 123.0
CMS2_k127_5241824_6 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 599.0
CMS2_k127_5241824_60 metal-dependent membrane protease K07052 - - 0.0000000000000000000000002314 116.0
CMS2_k127_5241824_61 CAAX protease self-immunity - - - 0.000000000000000000000003018 111.0
CMS2_k127_5241824_63 Isochorismatase family - - - 0.0000000000000000000002919 105.0
CMS2_k127_5241824_64 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000006787 98.0
CMS2_k127_5241824_68 TIGRFAM C_GCAxxG_C_C family - - - 0.00000000001533 72.0
CMS2_k127_5241824_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 608.0
CMS2_k127_5241824_70 - - - - 0.00001565 51.0
CMS2_k127_5241824_71 - - - - 0.00004451 51.0
CMS2_k127_5241824_72 Belongs to the AAA ATPase family K12196 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005768,GO:0006629,GO:0006810,GO:0006900,GO:0006914,GO:0006996,GO:0007032,GO:0007034,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0008202,GO:0009056,GO:0009987,GO:0010008,GO:0010256,GO:0012505,GO:0016020,GO:0016043,GO:0016050,GO:0016125,GO:0016192,GO:0016197,GO:0016236,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022607,GO:0030554,GO:0031090,GO:0031410,GO:0031982,GO:0032507,GO:0032509,GO:0032511,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033365,GO:0034067,GO:0034613,GO:0035639,GO:0036094,GO:0036452,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044440,GO:0044444,GO:0044446,GO:0044464,GO:0045053,GO:0045185,GO:0045324,GO:0046907,GO:0046983,GO:0051179,GO:0051234,GO:0051235,GO:0051259,GO:0051260,GO:0051641,GO:0051649,GO:0051651,GO:0061024,GO:0061919,GO:0065003,GO:0065007,GO:0065008,GO:0070676,GO:0070727,GO:0071704,GO:0071840,GO:0071985,GO:0097159,GO:0097367,GO:0097708,GO:0098588,GO:0098796,GO:0098805,GO:1901265,GO:1901360,GO:1901363,GO:1901615,GO:1902494,GO:1904949,GO:1990621 - 0.0002845 44.0
CMS2_k127_5241824_8 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 552.0
CMS2_k127_5241824_9 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 557.0
CMS2_k127_5257589_0 metal-dependent phosphohydrolase, HD sub domain K07037 - - 1.362e-198 641.0
CMS2_k127_5257589_1 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 559.0
CMS2_k127_5257589_10 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 356.0
CMS2_k127_5257589_11 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 347.0
CMS2_k127_5257589_12 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 335.0
CMS2_k127_5257589_13 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 315.0
CMS2_k127_5257589_14 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 306.0
CMS2_k127_5257589_15 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006228 270.0
CMS2_k127_5257589_16 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000006094 219.0
CMS2_k127_5257589_17 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000000000000000000000000000000005707 204.0
CMS2_k127_5257589_18 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000009743 173.0
CMS2_k127_5257589_19 deaminated base DNA N-glycosylase activity K03648,K21929 - 3.2.2.27 0.000000000000000000000000000000000000000009396 162.0
CMS2_k127_5257589_2 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 526.0
CMS2_k127_5257589_20 PFAM diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000000001644 141.0
CMS2_k127_5257589_21 PFAM Histidine triad (HIT) protein K02503 - - 0.000000000000000000000000000000000007491 140.0
CMS2_k127_5257589_22 transcriptional regulator - - - 0.0000000000000000000000000000000000933 141.0
CMS2_k127_5257589_23 GatB Yqey domain protein K09117 - - 0.00000000000000000000000000000003157 130.0
CMS2_k127_5257589_24 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000001216 124.0
CMS2_k127_5257589_25 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000000000002482 126.0
CMS2_k127_5257589_26 Cupin 2, conserved barrel domain protein - - - 0.0000000000000003893 84.0
CMS2_k127_5257589_27 LysM domain - - - 0.0000001718 64.0
CMS2_k127_5257589_28 Protein tyrosine kinase - - - 0.000003665 57.0
CMS2_k127_5257589_29 PFAM Tetratricopeptide repeat - - - 0.0001546 53.0
CMS2_k127_5257589_3 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 489.0
CMS2_k127_5257589_4 modification enzyme, MiaB family K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 474.0
CMS2_k127_5257589_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 467.0
CMS2_k127_5257589_6 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 459.0
CMS2_k127_5257589_7 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 407.0
CMS2_k127_5257589_8 PFAM AAA-4 family protein K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 409.0
CMS2_k127_5257589_9 deoxyribonuclease IV (phage-T4-induced) activity K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 377.0
CMS2_k127_5271680_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 545.0
CMS2_k127_5318329_0 Amino acid permease - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 4.285e-253 795.0
CMS2_k127_5318329_1 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 575.0
CMS2_k127_5318329_10 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000004557 162.0
CMS2_k127_5318329_11 peptidase C60 sortase A and B K07284 - 3.4.22.70 0.0000000000000000000000000000000002728 141.0
CMS2_k127_5318329_12 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000994 133.0
CMS2_k127_5318329_14 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000002895 144.0
CMS2_k127_5318329_15 phosphorelay signal transduction system - - - 0.000000000000000000000000001301 121.0
CMS2_k127_5318329_16 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000002343 118.0
CMS2_k127_5318329_17 serine-type endopeptidase activity K04043 - - 0.00000000106 62.0
CMS2_k127_5318329_2 ABC transporter transmembrane region K06147,K06148 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 565.0
CMS2_k127_5318329_3 ABC transporter transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 484.0
CMS2_k127_5318329_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 401.0
CMS2_k127_5318329_5 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 385.0
CMS2_k127_5318329_6 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 340.0
CMS2_k127_5318329_7 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008326 313.0
CMS2_k127_5318329_8 serine-type endopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 302.0
CMS2_k127_5318329_9 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000005927 222.0
CMS2_k127_5333941_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.279e-320 994.0
CMS2_k127_5333941_1 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 591.0
CMS2_k127_5333941_10 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000000000000000000000000000000831 155.0
CMS2_k127_5333941_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000002264 117.0
CMS2_k127_5333941_12 MazG-like family - - - 0.00000000000000000000000001853 118.0
CMS2_k127_5333941_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000004719 101.0
CMS2_k127_5333941_14 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000005316 108.0
CMS2_k127_5333941_17 Protein of unknown function (DUF1679) - - - 0.0000000169 66.0
CMS2_k127_5333941_18 PFAM Methyltransferase type 11 K00568 - 2.1.1.222,2.1.1.64 0.00000002052 66.0
CMS2_k127_5333941_2 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 324.0
CMS2_k127_5333941_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002995 288.0
CMS2_k127_5333941_4 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002113 266.0
CMS2_k127_5333941_5 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004552 275.0
CMS2_k127_5333941_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000659 255.0
CMS2_k127_5333941_7 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000008734 228.0
CMS2_k127_5333941_8 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000003748 211.0
CMS2_k127_5333941_9 cytokinin biosynthetic process K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000005068 190.0
CMS2_k127_5430888_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0 1472.0
CMS2_k127_5430888_1 Peptidase M16C associated K06972 - - 0.0 1075.0
CMS2_k127_5430888_10 - - - - 0.000000000001633 72.0
CMS2_k127_5430888_11 Aminoglycoside phosphotransferase - - - 0.00003261 55.0
CMS2_k127_5430888_2 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 596.0
CMS2_k127_5430888_3 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 407.0
CMS2_k127_5430888_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008048 268.0
CMS2_k127_5430888_5 FAD binding domain in molybdopterin dehydrogenase K03519,K12529 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000008299 207.0
CMS2_k127_5430888_6 Ferrous iron transport protein B C terminus K04759 - - 0.0000000000000000000000000000000000000000000000005325 180.0
CMS2_k127_5430888_7 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000002153 158.0
CMS2_k127_5430888_8 Thioesterase superfamily protein - - - 0.00000000000000000000000000000002563 130.0
CMS2_k127_5430888_9 iron ion homeostasis K04758 - - 0.0000000000003125 73.0
CMS2_k127_5452926_0 Transposase IS66 family K07484 - - 8.25e-216 682.0
CMS2_k127_5452926_1 Domain of unknown function (DUF4338) - - - 0.0000000000000000000000000000000000000000000000000000000002002 207.0
CMS2_k127_5519536_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1138.0
CMS2_k127_5519536_1 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 1.29e-217 681.0
CMS2_k127_5519536_10 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000001848 225.0
CMS2_k127_5519536_11 signal transduction histidine kinase K11623 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000002224 233.0
CMS2_k127_5519536_12 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000002631 221.0
CMS2_k127_5519536_13 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000001646 135.0
CMS2_k127_5519536_14 CAAX protease self-immunity - - - 0.0000000000000000000000000001024 124.0
CMS2_k127_5519536_15 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000003669 123.0
CMS2_k127_5519536_16 PFAM regulatory protein, MerR - - - 0.0000000000000000000000004407 113.0
CMS2_k127_5519536_18 Winged helix DNA-binding domain - - - 0.0000000000000000002311 92.0
CMS2_k127_5519536_19 - - - - 0.0000000000000001119 84.0
CMS2_k127_5519536_2 Peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 499.0
CMS2_k127_5519536_20 Phage integrase family - - - 0.0000000000001682 75.0
CMS2_k127_5519536_21 ABC-type multidrug transport system, permease component K01992 - - 0.000000002425 69.0
CMS2_k127_5519536_22 - - - - 0.000000009717 64.0
CMS2_k127_5519536_23 - - - - 0.000004022 58.0
CMS2_k127_5519536_24 CAAX protease self-immunity K07052 - - 0.00002803 55.0
CMS2_k127_5519536_3 PFAM PUCC protein K08226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 443.0
CMS2_k127_5519536_4 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 434.0
CMS2_k127_5519536_5 nitrite reductase, copper-containing K00368 - 1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 429.0
CMS2_k127_5519536_6 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 390.0
CMS2_k127_5519536_7 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 346.0
CMS2_k127_5519536_8 Zinc-uptake complex component A periplasmic K09818 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008019 271.0
CMS2_k127_5519536_9 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K11624 - - 0.0000000000000000000000000000000000000000000000000000000000000000789 228.0
CMS2_k127_5522027_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 419.0
CMS2_k127_5522027_1 Protein of unknown function DUF116 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 294.0
CMS2_k127_5522027_2 Binding-protein-dependent transport system inner membrane component K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004539 255.0
CMS2_k127_5522027_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000001507 230.0
CMS2_k127_5522027_4 DinB family - - - 0.000000000000000000000000000000000000000000000002239 179.0
CMS2_k127_5570688_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 432.0
CMS2_k127_5570688_1 Major facilitator Superfamily K08217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 386.0
CMS2_k127_5570688_10 Bacterial regulatory proteins, tetR family - - - 0.0000000000008761 76.0
CMS2_k127_5570688_2 Beta-lactamase K01453 - 3.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 327.0
CMS2_k127_5570688_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000003012 196.0
CMS2_k127_5570688_4 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000004248 168.0
CMS2_k127_5570688_5 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000000000000000000000000000003135 177.0
CMS2_k127_5570688_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000001971 142.0
CMS2_k127_5570688_7 Helix-turn-helix domain - - - 0.0000000000000000000000000005773 120.0
CMS2_k127_5570688_8 Virulence factor BrkB K07058 - - 0.000000000000000000000002583 116.0
CMS2_k127_5570688_9 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.000000000000001562 88.0
CMS2_k127_5927002_0 ABC transporter K06147 - - 1.871e-211 674.0
CMS2_k127_5927002_1 TrkA-C domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 509.0
CMS2_k127_5927002_2 - - - - 0.00000000000000000000000000000000001403 154.0
CMS2_k127_5927002_3 - - - - 0.0000000000000000000006325 100.0
CMS2_k127_6117956_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001619 240.0
CMS2_k127_6117956_1 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000001382 216.0
CMS2_k127_6117956_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.000000000000000000006691 92.0
CMS2_k127_6163448_0 Belongs to the GcvT family - - - 5.965e-317 990.0
CMS2_k127_6163448_1 FAD dependent oxidoreductase central domain - - - 2.117e-307 962.0
CMS2_k127_6163448_10 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 423.0
CMS2_k127_6163448_11 COG4175 ABC-type proline glycine betaine transport system ATPase component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 409.0
CMS2_k127_6163448_12 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 404.0
CMS2_k127_6163448_13 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 397.0
CMS2_k127_6163448_14 ABC-type proline glycine betaine transport system permease component K02001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 410.0
CMS2_k127_6163448_15 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 376.0
CMS2_k127_6163448_16 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 355.0
CMS2_k127_6163448_17 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 329.0
CMS2_k127_6163448_18 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 293.0
CMS2_k127_6163448_19 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 291.0
CMS2_k127_6163448_2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 2.488e-277 861.0
CMS2_k127_6163448_20 Acetylornithine deacetylase K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 293.0
CMS2_k127_6163448_21 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001259 287.0
CMS2_k127_6163448_22 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007439 267.0
CMS2_k127_6163448_23 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000569 265.0
CMS2_k127_6163448_24 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005786 265.0
CMS2_k127_6163448_25 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001381 260.0
CMS2_k127_6163448_26 glycine betaine transport K02002 - - 0.00000000000000000000000000000000000000000000000000000000000000025 231.0
CMS2_k127_6163448_27 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000001498 239.0
CMS2_k127_6163448_28 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000004734 227.0
CMS2_k127_6163448_29 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000008381 216.0
CMS2_k127_6163448_3 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 573.0
CMS2_k127_6163448_30 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000001049 221.0
CMS2_k127_6163448_31 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000004309 205.0
CMS2_k127_6163448_32 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000005715 180.0
CMS2_k127_6163448_33 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000002861 167.0
CMS2_k127_6163448_34 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000006769 165.0
CMS2_k127_6163448_35 helix_turn_helix ASNC type K03718 - - 0.0000000000000000000000000000000000001486 146.0
CMS2_k127_6163448_37 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000009488 122.0
CMS2_k127_6163448_38 - - - - 0.0000000000000000000000000003172 126.0
CMS2_k127_6163448_39 PFAM Acetyltransferase (GNAT) family - - - 0.000000000009475 72.0
CMS2_k127_6163448_4 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 565.0
CMS2_k127_6163448_40 Zinc-binding dehydrogenase - - - 0.000000003253 59.0
CMS2_k127_6163448_41 alpha beta hydrolase - - - 0.000002578 49.0
CMS2_k127_6163448_5 PFAM ABC transporter related K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 555.0
CMS2_k127_6163448_6 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 465.0
CMS2_k127_6163448_7 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 452.0
CMS2_k127_6163448_8 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 432.0
CMS2_k127_6163448_9 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 422.0
CMS2_k127_6231006_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 432.0
CMS2_k127_6231006_1 Domain of unknown function DUF87 K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 413.0
CMS2_k127_6231006_2 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 297.0
CMS2_k127_6253046_0 SMART AAA ATPase - - - 1.559e-218 684.0
CMS2_k127_6253046_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 637.0
CMS2_k127_6253046_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 410.0
CMS2_k127_6253046_11 Serine threonine protein kinase K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 405.0
CMS2_k127_6253046_12 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009603 391.0
CMS2_k127_6253046_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 334.0
CMS2_k127_6253046_14 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 332.0
CMS2_k127_6253046_15 aminoglycoside K00662 - 2.3.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 334.0
CMS2_k127_6253046_16 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 333.0
CMS2_k127_6253046_17 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 333.0
CMS2_k127_6253046_18 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 299.0
CMS2_k127_6253046_19 PFAM DegV family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 291.0
CMS2_k127_6253046_2 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 599.0
CMS2_k127_6253046_20 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002661 271.0
CMS2_k127_6253046_21 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004234 267.0
CMS2_k127_6253046_22 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004483 255.0
CMS2_k127_6253046_23 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000103 250.0
CMS2_k127_6253046_24 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000000000000000000000000006608 233.0
CMS2_k127_6253046_25 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000005201 231.0
CMS2_k127_6253046_26 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.0000000000000000000000000000000000000000000000000000000000000001875 231.0
CMS2_k127_6253046_28 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000003034 199.0
CMS2_k127_6253046_29 GrpB protein - - - 0.0000000000000000000000000000000000000000000000005028 180.0
CMS2_k127_6253046_3 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 556.0
CMS2_k127_6253046_30 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000001151 177.0
CMS2_k127_6253046_31 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000009163 161.0
CMS2_k127_6253046_32 - - - - 0.0000000000000000000000000000000000000003776 158.0
CMS2_k127_6253046_33 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000014 141.0
CMS2_k127_6253046_34 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000000001085 129.0
CMS2_k127_6253046_35 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000414 132.0
CMS2_k127_6253046_36 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000003337 112.0
CMS2_k127_6253046_37 Protein of unknown function (DUF1706) - - - 0.00000000000000000000000006816 113.0
CMS2_k127_6253046_38 DNA-binding transcription factor activity K03892 - - 0.00000000000000000000002925 105.0
CMS2_k127_6253046_39 PFAM Pyrrolo-quinoline quinone - - - 0.000000000000000000000128 111.0
CMS2_k127_6253046_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 532.0
CMS2_k127_6253046_40 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000537 93.0
CMS2_k127_6253046_41 Protein of unknown function (DUF2905) - - - 0.0000000002199 63.0
CMS2_k127_6253046_42 CarD family K07736 - - 0.00000003648 61.0
CMS2_k127_6253046_43 Ribosomal protein S21 K02970 - - 0.00000009385 57.0
CMS2_k127_6253046_5 PFAM Amidohydrolase 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 534.0
CMS2_k127_6253046_6 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 516.0
CMS2_k127_6253046_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 493.0
CMS2_k127_6253046_8 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 450.0
CMS2_k127_6253046_9 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 436.0
CMS2_k127_6309104_0 synthase K13612,K13614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 389.0
CMS2_k127_6362409_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 337.0
CMS2_k127_6362409_1 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000001771 186.0
CMS2_k127_6362409_3 PFAM Glycosyl transferase, group 1 - - - 0.00000000007072 65.0
CMS2_k127_6362409_4 Glycosyltransferase Family 4 - - - 0.0000003362 56.0
CMS2_k127_6397588_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 527.0
CMS2_k127_6397588_1 Peptidase family S41 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 497.0
CMS2_k127_6397588_10 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000006366 110.0
CMS2_k127_6397588_11 - - - - 0.0000000000000005305 93.0
CMS2_k127_6397588_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000006096 66.0
CMS2_k127_6397588_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 430.0
CMS2_k127_6397588_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005584 301.0
CMS2_k127_6397588_4 PFAM secretion protein HlyD family protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 308.0
CMS2_k127_6397588_5 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 296.0
CMS2_k127_6397588_6 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000000000679 177.0
CMS2_k127_6397588_7 galactose-6-phosphate isomerase activity K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000002189 174.0
CMS2_k127_6397588_8 metal cluster binding K06940,K18475 - - 0.00000000000000000000000000000000000008765 145.0
CMS2_k127_6397588_9 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000005215 128.0
CMS2_k127_6438841_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 437.0
CMS2_k127_6438841_1 - - - - 0.00000000000000000000000000003002 123.0
CMS2_k127_6438841_2 COG1278 Cold shock proteins K03704 - - 0.00000000000000000000000005035 108.0
CMS2_k127_6438841_3 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000703 83.0
CMS2_k127_6438841_4 YwiC-like protein - - - 0.0000000000001653 81.0
CMS2_k127_6438841_6 Phage integrase family - - - 0.0008038 46.0
CMS2_k127_6440501_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 3.382e-308 952.0
CMS2_k127_6440501_1 Heat shock 70 kDa protein K04043 - - 2.742e-292 909.0
CMS2_k127_6440501_10 ThiS family K03636 - - 0.00006997 49.0
CMS2_k127_6440501_2 PFAM magnesium chelatase ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 591.0
CMS2_k127_6440501_3 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 587.0
CMS2_k127_6440501_4 ferrous iron transmembrane transporter activity K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 353.0
CMS2_k127_6440501_5 iron ion homeostasis K03322,K03709,K04758 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001042 289.0
CMS2_k127_6440501_6 - - - - 0.0000000000000000000000000000003443 130.0
CMS2_k127_6440501_7 TIGRFAM MoaD family protein K03636 - - 0.0000000000000000000000000008018 115.0
CMS2_k127_6440501_8 DNA-binding transcription factor activity K03892 - - 0.00000000000000001009 87.0
CMS2_k127_6440501_9 transporter of a GTP-driven Fe(2 ) uptake system - - - 0.00000004199 57.0
CMS2_k127_6466866_0 amine dehydrogenase activity K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 393.0
CMS2_k127_6494476_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1965.0
CMS2_k127_6494476_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.254e-274 869.0
CMS2_k127_6494476_10 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000003353 224.0
CMS2_k127_6494476_11 organic phosphonate transmembrane transporter activity K02042 - - 0.000000000000000000000000000000000000000000000003859 194.0
CMS2_k127_6494476_12 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000003815 150.0
CMS2_k127_6494476_13 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000001217 159.0
CMS2_k127_6494476_14 DUF218 domain - - - 0.0000000000000000000000000000000001006 143.0
CMS2_k127_6494476_15 Protein of unknown function (DUF559) - - - 0.000000000000000000000000002701 114.0
CMS2_k127_6494476_16 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000001543 117.0
CMS2_k127_6494476_17 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00004496 56.0
CMS2_k127_6494476_2 protein histidine kinase activity K02484,K07636,K07642 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016036,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0035556,GO:0036211,GO:0042578,GO:0042594,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 2.866e-223 731.0
CMS2_k127_6494476_3 Tetratricopeptide TPR_2 repeat protein - - - 1.977e-200 644.0
CMS2_k127_6494476_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 518.0
CMS2_k127_6494476_5 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 434.0
CMS2_k127_6494476_6 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 342.0
CMS2_k127_6494476_7 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 329.0
CMS2_k127_6494476_8 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001787 262.0
CMS2_k127_6494476_9 TIGRFAM metal dependent phophohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004975 256.0
CMS2_k127_65045_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 2.014e-222 700.0
CMS2_k127_65045_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 2.7.7.7 2.005e-211 689.0
CMS2_k127_65045_10 PFAM Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 301.0
CMS2_k127_65045_11 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 300.0
CMS2_k127_65045_12 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 299.0
CMS2_k127_65045_13 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 313.0
CMS2_k127_65045_14 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 290.0
CMS2_k127_65045_15 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004493 274.0
CMS2_k127_65045_16 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000001915 260.0
CMS2_k127_65045_17 sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005497 251.0
CMS2_k127_65045_18 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000000000003126 247.0
CMS2_k127_65045_19 signal-transduction protein containing cAMP-binding and CBS domains - - - 0.0000000000000000000000000000000000000000000000000000000000000033 238.0
CMS2_k127_65045_2 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 582.0
CMS2_k127_65045_20 PFAM basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000001004 234.0
CMS2_k127_65045_21 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000001837 210.0
CMS2_k127_65045_22 glycolate biosynthetic process K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000001901 205.0
CMS2_k127_65045_23 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000002495 196.0
CMS2_k127_65045_24 - - - - 0.0000000000000000000000000000000000000000000000006393 196.0
CMS2_k127_65045_25 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000011 181.0
CMS2_k127_65045_26 Rubrerythrin K22336 - 1.16.3.1 0.000000000000000000000000000000000000000000000009136 177.0
CMS2_k127_65045_27 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000003476 166.0
CMS2_k127_65045_28 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.0000000000000000000000000000000000003255 147.0
CMS2_k127_65045_29 2 iron, 2 sulfur cluster binding K02823,K05368 - 1.16.1.3,1.5.1.41 0.0000000000000000000000000009404 121.0
CMS2_k127_65045_3 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 542.0
CMS2_k127_65045_30 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K01185,K02395,K19223 - 3.2.1.17 0.00000000000000000000000005324 124.0
CMS2_k127_65045_31 zinc-ribbon domain - - - 0.000000000000000000000001133 110.0
CMS2_k127_65045_32 L,D-transpeptidase catalytic domain - - - 0.0000000000000000001344 100.0
CMS2_k127_65045_34 - - - - 0.000000000000000009756 84.0
CMS2_k127_65045_35 - - - - 0.00000002823 64.0
CMS2_k127_65045_36 AntiSigma factor - - - 0.000001061 60.0
CMS2_k127_65045_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 446.0
CMS2_k127_65045_5 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 444.0
CMS2_k127_65045_6 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 349.0
CMS2_k127_65045_7 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 327.0
CMS2_k127_65045_8 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 324.0
CMS2_k127_65045_9 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 320.0
CMS2_k127_6534164_0 PFAM glycosyl transferase, family 51 - - - 0.0 1098.0
CMS2_k127_6534164_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 463.0
CMS2_k127_6534164_10 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000005018 244.0
CMS2_k127_6534164_11 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000001199 224.0
CMS2_k127_6534164_12 PFAM histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000002593 201.0
CMS2_k127_6534164_13 Dimerisation domain of Zinc Transporter - - - 0.00000000000000000000000000000000000000000000000000000006687 213.0
CMS2_k127_6534164_14 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000000000000000000000003665 185.0
CMS2_k127_6534164_15 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000000000000000000000000967 169.0
CMS2_k127_6534164_16 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000004458 156.0
CMS2_k127_6534164_17 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000001586 151.0
CMS2_k127_6534164_18 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000007383 126.0
CMS2_k127_6534164_19 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000002568 118.0
CMS2_k127_6534164_20 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000001637 68.0
CMS2_k127_6534164_21 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000002147 69.0
CMS2_k127_6534164_22 Cyclic-di-AMP receptor - - - 0.0000000001151 65.0
CMS2_k127_6534164_23 Heat shock protein K03668 - - 0.00000000131 66.0
CMS2_k127_6534164_24 Protein kinase domain K12132 - 2.7.11.1 0.00002642 56.0
CMS2_k127_6534164_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 411.0
CMS2_k127_6534164_4 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 355.0
CMS2_k127_6534164_5 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 365.0
CMS2_k127_6534164_6 Alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 317.0
CMS2_k127_6534164_7 Sodium/hydrogen exchanger family K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 314.0
CMS2_k127_6534164_8 CHASE2 K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000104 295.0
CMS2_k127_6534164_9 PFAM thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000002615 267.0
CMS2_k127_6600125_0 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 5e-284 898.0
CMS2_k127_6600125_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.639e-238 751.0
CMS2_k127_6600125_10 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 296.0
CMS2_k127_6600125_11 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001078 270.0
CMS2_k127_6600125_12 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001461 260.0
CMS2_k127_6600125_13 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000005067 249.0
CMS2_k127_6600125_14 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000008947 239.0
CMS2_k127_6600125_15 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000001303 215.0
CMS2_k127_6600125_16 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000008721 195.0
CMS2_k127_6600125_17 - - - - 0.0000000000000000000000000000000000000000000000001419 183.0
CMS2_k127_6600125_18 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000000000000000000000001446 165.0
CMS2_k127_6600125_19 acetyltransferase - - - 0.000000000000000000000000000000000000002411 153.0
CMS2_k127_6600125_2 His Kinase A (phosphoacceptor) domain - - - 7.175e-203 644.0
CMS2_k127_6600125_20 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000007293 166.0
CMS2_k127_6600125_21 addiction module antidote protein, CC2985 family - - - 0.0000000000000000000000000000000000002964 143.0
CMS2_k127_6600125_22 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000001573 138.0
CMS2_k127_6600125_23 Transcriptional regulator - - - 0.00000000000000000000000000000002951 129.0
CMS2_k127_6600125_24 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000000000008012 118.0
CMS2_k127_6600125_25 Psort location Cytoplasmic, score - - - 0.00000000000000000000000001413 113.0
CMS2_k127_6600125_26 BlaR1 peptidase M56 - - - 0.00000000000000000000000002457 124.0
CMS2_k127_6600125_27 PFAM membrane protein of K08972 - - 0.00000000000000000000000005552 111.0
CMS2_k127_6600125_28 Rdx family K07401 - - 0.0000000004122 62.0
CMS2_k127_6600125_29 Acetyltransferase (GNAT) domain - - - 0.0000000006687 70.0
CMS2_k127_6600125_3 Participates in both transcription termination and antitermination K02600 - - 4.751e-194 623.0
CMS2_k127_6600125_30 protein with SCP PR1 domains - - - 0.000000001591 69.0
CMS2_k127_6600125_31 - - - - 0.0004168 51.0
CMS2_k127_6600125_4 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 517.0
CMS2_k127_6600125_5 Aminotransferase class-III K00821,K03918,K07250,K13524,K20428 - 2.6.1.11,2.6.1.17,2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 496.0
CMS2_k127_6600125_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 488.0
CMS2_k127_6600125_7 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 395.0
CMS2_k127_6600125_8 COG2309 Leucyl aminopeptidase (aminopeptidase T) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 391.0
CMS2_k127_6600125_9 CpXC protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 341.0
CMS2_k127_6622537_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 1.164e-248 777.0
CMS2_k127_6622537_1 PFAM deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 296.0
CMS2_k127_6622537_2 homoserine kinase type II (protein kinase fold) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004418 255.0
CMS2_k127_6622537_3 metal cluster binding K06940,K18475 - - 0.0000000000000000000000000000000000000000000000000000000000003444 216.0
CMS2_k127_6622537_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000009731 197.0
CMS2_k127_6622537_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000000000000000000228 158.0
CMS2_k127_6677065_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 364.0
CMS2_k127_6677065_1 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 283.0
CMS2_k127_6677065_2 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000007509 190.0
CMS2_k127_6677065_3 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.000000000000000000000000000000001881 138.0
CMS2_k127_6677065_4 4-vinyl reductase, 4VR K07013,K17763 - - 0.000000000000000000000000000001841 129.0
CMS2_k127_6979132_0 Tex-like protein N-terminal domain K06959 - - 8.942e-284 887.0
CMS2_k127_6979132_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 9.159e-226 710.0
CMS2_k127_6979132_11 stress-induced mitochondrial fusion K04066,K07037,K17266 - - 0.0000000000000000000007087 111.0
CMS2_k127_6979132_12 Cytochrome c, class I - - - 0.000000000000001626 83.0
CMS2_k127_6979132_13 Glycosyl hydrolases family 25 - - - 0.00000001923 65.0
CMS2_k127_6979132_14 Rubrerythrin - - - 0.0002323 49.0
CMS2_k127_6979132_15 Represses a number of genes involved in the response to DNA damage (SOS response) - - - 0.0002899 53.0
CMS2_k127_6979132_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 570.0
CMS2_k127_6979132_3 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 531.0
CMS2_k127_6979132_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 458.0
CMS2_k127_6979132_5 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 315.0
CMS2_k127_6979132_6 Domain of unknown function(DUF2779) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002051 285.0
CMS2_k127_6979132_7 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.0000000000000000000000000000000000000000000000002595 184.0
CMS2_k127_6979132_8 PFAM thioesterase superfamily protein K07107 - - 0.00000000000000000000000000000001177 132.0
CMS2_k127_6979132_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000002838 117.0
CMS2_k127_7032688_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.118e-297 922.0
CMS2_k127_7032688_1 Tetratricopeptide TPR_2 repeat protein - - - 1.296e-289 925.0
CMS2_k127_7032688_2 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 482.0
CMS2_k127_7032688_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 460.0
CMS2_k127_7032688_4 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 317.0
CMS2_k127_7032688_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001335 289.0
CMS2_k127_7032688_6 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000001392 148.0
CMS2_k127_7032688_7 lysyltransferase activity K07027 - - 0.0000000000000000000000000000003113 135.0
CMS2_k127_751610_0 Aldehyde dehydrogenase 16 family member A1 K00128 - 1.2.1.3 0.0 1030.0
CMS2_k127_751610_1 Protein of unknown function, DUF255 K06888 - - 2.389e-227 723.0
CMS2_k127_751610_10 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000000000000000000000107 208.0
CMS2_k127_751610_11 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000002466 198.0
CMS2_k127_751610_12 conserved repeat domain protein - - - 0.0000000000000000000000002007 124.0
CMS2_k127_751610_13 ABC transporter substrate-binding protein PnrA-like K02058,K05519,K07335 - - 0.0000000000000000000000002592 118.0
CMS2_k127_751610_14 - - - - 0.000002383 59.0
CMS2_k127_751610_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.688e-204 642.0
CMS2_k127_751610_3 PFAM ABC transporter related K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 602.0
CMS2_k127_751610_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 448.0
CMS2_k127_751610_5 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 431.0
CMS2_k127_751610_6 PFAM basic membrane lipoprotein K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 431.0
CMS2_k127_751610_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 409.0
CMS2_k127_751610_8 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000002496 241.0
CMS2_k127_751610_9 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000000000000000000000000000000000000000000000000000000004749 246.0
CMS2_k127_776283_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1065.0
CMS2_k127_776283_1 Nacht domain K13730 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 362.0
CMS2_k127_776283_10 Glucose / Sorbosone dehydrogenase K00428,K01728 - 1.11.1.5,4.2.2.2 0.000002418 58.0
CMS2_k127_776283_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009712 287.0
CMS2_k127_776283_3 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.00000000000000000000000000000000000000544 154.0
CMS2_k127_776283_4 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000000000000000000004154 118.0
CMS2_k127_776283_5 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000002608 98.0
CMS2_k127_776283_6 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000000009233 89.0
CMS2_k127_776283_7 Ribosomal protein S21 K02970 - - 0.0000000000000002691 80.0
CMS2_k127_776283_8 Family of unknown function (DUF5309) - - - 0.00000000007904 74.0
CMS2_k127_776283_9 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000005297 70.0
CMS2_k127_902547_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 2.178e-296 924.0
CMS2_k127_902547_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.975e-242 758.0
CMS2_k127_902547_10 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 436.0
CMS2_k127_902547_11 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 426.0
CMS2_k127_902547_12 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 431.0
CMS2_k127_902547_13 trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 427.0
CMS2_k127_902547_14 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 393.0
CMS2_k127_902547_15 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 310.0
CMS2_k127_902547_16 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 300.0
CMS2_k127_902547_17 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 296.0
CMS2_k127_902547_18 PFAM ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002297 282.0
CMS2_k127_902547_19 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000003059 252.0
CMS2_k127_902547_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 550.0
CMS2_k127_902547_20 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000006143 248.0
CMS2_k127_902547_21 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000001188 237.0
CMS2_k127_902547_22 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000001461 163.0
CMS2_k127_902547_23 gntR family - - - 0.000000000000000000000000000000000000009012 153.0
CMS2_k127_902547_24 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000002005 154.0
CMS2_k127_902547_25 CBS domain K04767 - - 0.00000000000000000000000000000000000007652 150.0
CMS2_k127_902547_26 gntR family - - - 0.0000000000000000000000000000006976 131.0
CMS2_k127_902547_27 Hydantoinaseoxoprolinase domain protein - - - 0.000000000000000000000000000001627 124.0
CMS2_k127_902547_28 - - - - 0.000000000000007218 80.0
CMS2_k127_902547_3 Hydantoinaseoxoprolinase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 505.0
CMS2_k127_902547_4 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 482.0
CMS2_k127_902547_5 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K20447 - 1.17.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 481.0
CMS2_k127_902547_6 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 457.0
CMS2_k127_902547_7 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 456.0
CMS2_k127_902547_8 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 447.0
CMS2_k127_902547_9 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 435.0