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Overview

ID MAG00422
Name CMS2_bin.32
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Thiomicrospirales
Family Thiomicrospiraceae
Genus Thiomicrorhabdus
Species
Assembly information
Completeness (%) 85.37
Contamination (%) 3.78
GC content (%) 43.0
N50 (bp) 8,814
Genome size (bp) 2,290,167

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2124

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1040346_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0 1183.0
CMS2_k127_1040346_1 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 526.0
CMS2_k127_1040346_2 - - - - 0.0001873 50.0
CMS2_k127_1062934_0 Major Facilitator Superfamily K02575 - - 8.073e-301 924.0
CMS2_k127_1062934_1 Pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 397.0
CMS2_k127_1063753_0 MafB19-like deaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 444.0
CMS2_k127_1063753_1 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000003046 117.0
CMS2_k127_1063753_2 - - - - 0.00000000000000000001118 94.0
CMS2_k127_1077392_0 Putative diguanylate phosphodiesterase - - - 0.0 1077.0
CMS2_k127_1077392_1 Putative diguanylate phosphodiesterase - - - 2e-323 1007.0
CMS2_k127_1077392_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.361e-249 771.0
CMS2_k127_1077392_3 TIGRFAM 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 562.0
CMS2_k127_1077392_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 426.0
CMS2_k127_1077392_5 organic phosphonate transport K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 376.0
CMS2_k127_1077392_6 glutamate--cysteine ligase K01919 - 6.3.2.2 0.00000000000000000000000000001298 119.0
CMS2_k127_1089328_1 peptidoglycan biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 403.0
CMS2_k127_1089328_2 Protein conserved in bacteria K09860 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 296.0
CMS2_k127_1136174_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1485.0
CMS2_k127_1136174_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1299.0
CMS2_k127_1136174_10 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000000000000002969 220.0
CMS2_k127_1136174_11 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000000000000155 160.0
CMS2_k127_1136174_12 Ribosomal protein L35 K02916 - - 0.000000000000000000000000000000004005 128.0
CMS2_k127_1136174_13 YKOF-related Family - - - 0.0000000000000000000000002949 107.0
CMS2_k127_1136174_14 hydrolase K01048 - 3.1.1.5 0.000007976 48.0
CMS2_k127_1136174_2 TonB-dependent Receptor Plug Domain - - - 5.069e-261 821.0
CMS2_k127_1136174_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 1.581e-212 661.0
CMS2_k127_1136174_4 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 514.0
CMS2_k127_1136174_5 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 473.0
CMS2_k127_1136174_6 O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 386.0
CMS2_k127_1136174_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 371.0
CMS2_k127_1136174_8 nicotinamide mononucleotide transporter K03811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 342.0
CMS2_k127_1136174_9 PFAM MerR family regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001991 248.0
CMS2_k127_1156696_0 ribonuclease, Rne Rng family K08301 - - 1.73e-311 955.0
CMS2_k127_1156696_1 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009186 348.0
CMS2_k127_1156696_2 TIGRFAM TIGR02099 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 281.0
CMS2_k127_1156696_3 bis(5'-adenosyl)-triphosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004454 215.0
CMS2_k127_1195317_0 PFAM MoeZ MoeB domain K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008685 479.0
CMS2_k127_1195317_1 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 418.0
CMS2_k127_1195317_2 With MotB forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 358.0
CMS2_k127_1195317_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000009889 258.0
CMS2_k127_1205441_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1544.0
CMS2_k127_1205441_1 TIGRFAM molybdenum cofactor synthesis K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 373.0
CMS2_k127_1205441_2 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000002521 102.0
CMS2_k127_121158_0 inner membrane component K02034,K15582 - - 7.822e-262 810.0
CMS2_k127_121158_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005065 570.0
CMS2_k127_121158_2 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 368.0
CMS2_k127_1213609_0 FeS assembly protein SufB K09014 - - 0.0 996.0
CMS2_k127_1213609_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 3.521e-284 875.0
CMS2_k127_1213609_10 ABC-type Zn2 transport system, periplasmic component surface adhesin K09815 - - 0.00000000000000000000000000000000000000000000000000000006515 196.0
CMS2_k127_1213609_11 Protein of unknown function (DUF721) - - - 0.0000000000000000000000000000000001338 132.0
CMS2_k127_1213609_2 FeS assembly protein SufD K09015 - - 1.466e-268 829.0
CMS2_k127_1213609_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 1.805e-263 813.0
CMS2_k127_1213609_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.55e-260 804.0
CMS2_k127_1213609_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 3.035e-215 669.0
CMS2_k127_1213609_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 570.0
CMS2_k127_1213609_7 FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 498.0
CMS2_k127_1213609_8 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 413.0
CMS2_k127_1213609_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 409.0
CMS2_k127_1230908_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 9.671e-254 784.0
CMS2_k127_1230908_1 Belongs to the GARS family K01945,K13713 - 6.3.2.6,6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 477.0
CMS2_k127_1230908_2 Late competence development protein ComFB - - - 0.0000000000000000000000000000000000000000000000001601 177.0
CMS2_k127_1248263_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 3.782e-232 720.0
CMS2_k127_1248263_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 462.0
CMS2_k127_1248263_2 riboflavin synthase, alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 384.0
CMS2_k127_1248263_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000005533 69.0
CMS2_k127_1264563_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 3.526e-302 927.0
CMS2_k127_1264563_1 Cupin superfamily protein K18850 - 1.14.11.47 1.519e-253 782.0
CMS2_k127_1264563_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000004775 157.0
CMS2_k127_1281958_0 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 552.0
CMS2_k127_1281958_1 Pfam:DUF955 - - - 0.000000000000000000000000000000000000000000000000000000000000000001446 231.0
CMS2_k127_1281958_2 - - - - 0.000000000000000000000000000000000000000000000000000004785 192.0
CMS2_k127_1281958_3 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000002588 152.0
CMS2_k127_1281958_4 Multiubiquitin - - - 0.0000000000000000000000000000000001446 134.0
CMS2_k127_1281958_5 Uncharacterized protein conserved in bacteria (DUF2188) - - - 0.00000000000000000000000000001016 119.0
CMS2_k127_1281958_6 May be involved in recombination K03554 GO:0000018,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009295,GO:0019219,GO:0019222,GO:0031323,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363 - 0.00000000000000000000001044 102.0
CMS2_k127_1293156_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 2.417e-313 963.0
CMS2_k127_1293156_1 PFAM TonB-dependent Receptor K02014 - - 1.627e-291 909.0
CMS2_k127_1293156_10 Belongs to the dCTP deaminase family K01494 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009314,GO:0009394,GO:0009628,GO:0009987,GO:0015949,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 405.0
CMS2_k127_1293156_11 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 399.0
CMS2_k127_1293156_12 Dienelactone hydrolase family K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 389.0
CMS2_k127_1293156_13 PFAM Copper chaperone SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 346.0
CMS2_k127_1293156_14 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 323.0
CMS2_k127_1293156_15 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 313.0
CMS2_k127_1293156_17 Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008856 307.0
CMS2_k127_1293156_18 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 293.0
CMS2_k127_1293156_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000275 264.0
CMS2_k127_1293156_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 6.981e-223 691.0
CMS2_k127_1293156_20 RF-1 domain K15034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001467 241.0
CMS2_k127_1293156_21 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000333 244.0
CMS2_k127_1293156_22 - - - - 0.00000000000000000000000000000000000000000000000000009611 186.0
CMS2_k127_1293156_24 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000007411 49.0
CMS2_k127_1293156_3 outer membrane efflux protein - - - 3.822e-220 691.0
CMS2_k127_1293156_4 Uncharacterized protein conserved in bacteria (DUF2066) K09938 - - 7.757e-197 620.0
CMS2_k127_1293156_6 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 482.0
CMS2_k127_1293156_7 Domain of unknown function (DUF4395) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 470.0
CMS2_k127_1293156_8 Belongs to the DnaA family. HdA subfamily K10763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 451.0
CMS2_k127_1299244_0 P22 coat protein - gene protein 5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 352.0
CMS2_k127_1299244_1 - - - - 0.0000000000001338 74.0
CMS2_k127_1299244_2 phage protein Ypo2111 SWALL Q8ZEP9 (EMBL AJ414151) (176 aa) fasta scores E() 4.1, 26.94 id in 167 aa - - - 0.0001668 44.0
CMS2_k127_1347282_0 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0 1192.0
CMS2_k127_1347282_1 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 3.268e-226 705.0
CMS2_k127_1347282_2 Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) K00557 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0019843,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.35 1.777e-217 677.0
CMS2_k127_1347282_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 557.0
CMS2_k127_1347282_4 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 412.0
CMS2_k127_1351908_0 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 584.0
CMS2_k127_1351908_1 Eukaryotic-type carbonic anhydrase K01674 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 545.0
CMS2_k127_135234_0 PFAM Transglycosylase SLT domain K08309 - - 0.0 1192.0
CMS2_k127_135234_1 PFAM Transglycosylase SLT domain K08307 - - 6.011e-316 974.0
CMS2_k127_135234_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 5.797e-288 887.0
CMS2_k127_135234_3 ATP-dependent helicase K03578 - 3.6.4.13 4.952e-206 643.0
CMS2_k127_135234_4 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 498.0
CMS2_k127_135234_5 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 477.0
CMS2_k127_135234_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 457.0
CMS2_k127_135234_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 450.0
CMS2_k127_135234_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007281 400.0
CMS2_k127_135234_9 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005067 271.0
CMS2_k127_1353599_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 9.678e-225 698.0
CMS2_k127_1353599_1 PFAM Haloacid dehalogenase-like hydrolase K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 446.0
CMS2_k127_1353599_2 short-chain dehydrogenase reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 402.0
CMS2_k127_1353599_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 301.0
CMS2_k127_1353599_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000001167 132.0
CMS2_k127_1364434_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 4.796e-279 860.0
CMS2_k127_1364434_1 PFAM CBS domain - - - 7.828e-237 737.0
CMS2_k127_1364434_2 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 469.0
CMS2_k127_1364434_3 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 467.0
CMS2_k127_1382775_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1560.0
CMS2_k127_1382775_1 Histidine kinase - - - 0.0 1367.0
CMS2_k127_1382775_10 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 434.0
CMS2_k127_1382775_11 Sporulation related domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 401.0
CMS2_k127_1382775_12 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 366.0
CMS2_k127_1382775_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002174 333.0
CMS2_k127_1382775_14 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 323.0
CMS2_k127_1382775_15 diguanylate cyclase K13590 - 2.7.7.65 0.0000000000000005045 78.0
CMS2_k127_1382775_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0 1133.0
CMS2_k127_1382775_3 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 2.027e-292 900.0
CMS2_k127_1382775_4 TrkA-N domain K03499 - - 2.545e-289 890.0
CMS2_k127_1382775_5 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 2.867e-274 845.0
CMS2_k127_1382775_6 response regulator receiver - - - 2.709e-272 839.0
CMS2_k127_1382775_7 TIGRFAM DNA protecting protein DprA K04096 - - 2.644e-214 668.0
CMS2_k127_1382775_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 577.0
CMS2_k127_1382775_9 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 518.0
CMS2_k127_1387721_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.789e-293 903.0
CMS2_k127_1387721_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 2.977e-248 768.0
CMS2_k127_1387721_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000016 185.0
CMS2_k127_1387721_3 cell division K03586 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.00000000000000000000000000000000000001493 146.0
CMS2_k127_1395572_0 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.5e-323 990.0
CMS2_k127_1395572_1 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 487.0
CMS2_k127_1395572_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 431.0
CMS2_k127_1395572_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 351.0
CMS2_k127_1395572_4 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009409 260.0
CMS2_k127_1395572_5 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000000000239 162.0
CMS2_k127_1401199_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1868.0
CMS2_k127_1401199_1 major facilitator superfamily - - - 3.64e-270 836.0
CMS2_k127_1401199_2 Protein of unknown function (DUF2927) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 434.0
CMS2_k127_1401199_3 ThiF family K22132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 391.0
CMS2_k127_1401199_4 periplasmic secreted protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 364.0
CMS2_k127_1401199_5 TatD family K03424 - - 0.000000000000000000000000000000000000000000002271 165.0
CMS2_k127_1426486_0 Flagellar hook protein FlgE K02390 - - 1.536e-278 862.0
CMS2_k127_1426486_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 2.811e-224 696.0
CMS2_k127_1426486_2 flagellar basal-body rod protein FlgG K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 512.0
CMS2_k127_1426486_3 TIGRFAM flagellar basal-body rod protein FlgF K02391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 464.0
CMS2_k127_1426486_4 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 438.0
CMS2_k127_1426486_5 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008177 410.0
CMS2_k127_1426486_6 curli production assembly transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 334.0
CMS2_k127_1426486_7 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002943 256.0
CMS2_k127_1426486_8 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001418 243.0
CMS2_k127_1428305_0 TIGRFAM TIGR02099 family protein - - - 0.0 2039.0
CMS2_k127_1428305_1 ribonuclease, Rne Rng family K08301 - - 0.00000000000000001698 81.0
CMS2_k127_1468774_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 300.0
CMS2_k127_1468774_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000004268 249.0
CMS2_k127_1468774_2 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000008781 186.0
CMS2_k127_1505683_0 fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 438.0
CMS2_k127_1505683_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 392.0
CMS2_k127_1505683_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006951 294.0
CMS2_k127_1505683_3 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000001292 177.0
CMS2_k127_1527793_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 9.4e-323 990.0
CMS2_k127_1527793_1 Belongs to the GARS family K01945,K13713 - 6.3.2.6,6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 447.0
CMS2_k127_1527793_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 411.0
CMS2_k127_1527793_3 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 - - 0.00000000000000000000000000000000000000001991 153.0
CMS2_k127_1537165_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1304.0
CMS2_k127_1537165_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1231.0
CMS2_k127_1537165_10 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 7.939e-259 799.0
CMS2_k127_1537165_11 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 3.877e-245 758.0
CMS2_k127_1537165_12 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 4.581e-237 739.0
CMS2_k127_1537165_13 Diguanylate cyclase - - - 1.046e-226 726.0
CMS2_k127_1537165_14 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 2.117e-221 689.0
CMS2_k127_1537165_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 5.353e-215 669.0
CMS2_k127_1537165_16 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 1.587e-213 664.0
CMS2_k127_1537165_17 Peptidase family M23 - - - 1.516e-194 609.0
CMS2_k127_1537165_18 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 559.0
CMS2_k127_1537165_19 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 537.0
CMS2_k127_1537165_2 Proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.0 1209.0
CMS2_k127_1537165_20 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 522.0
CMS2_k127_1537165_21 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 496.0
CMS2_k127_1537165_22 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 442.0
CMS2_k127_1537165_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006327 430.0
CMS2_k127_1537165_24 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 426.0
CMS2_k127_1537165_25 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000894 409.0
CMS2_k127_1537165_26 ChrR Cupin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 387.0
CMS2_k127_1537165_27 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 382.0
CMS2_k127_1537165_28 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 375.0
CMS2_k127_1537165_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 342.0
CMS2_k127_1537165_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0 1002.0
CMS2_k127_1537165_30 NADH dehydrogenase K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 342.0
CMS2_k127_1537165_31 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 337.0
CMS2_k127_1537165_32 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 291.0
CMS2_k127_1537165_33 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000000891 211.0
CMS2_k127_1537165_34 RNA-binding protein K07574 - - 0.00000000000000000000000000000000000000000000000000000000006698 204.0
CMS2_k127_1537165_35 - - - - 0.00000000000000000000000000000000000000000000000000000001974 199.0
CMS2_k127_1537165_36 Protein of unknown function (DUF2818) - - - 0.0000000000000000000000000000000000000000000000000009679 184.0
CMS2_k127_1537165_37 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000000000000000000001072 181.0
CMS2_k127_1537165_38 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000000000000000000000002987 179.0
CMS2_k127_1537165_39 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000147 139.0
CMS2_k127_1537165_4 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 3.601e-315 967.0
CMS2_k127_1537165_40 peptidoglycan binding K01286,K02450,K20074 - 3.1.3.16,3.4.16.4 0.000000000000000000000001774 109.0
CMS2_k127_1537165_42 - - - - 0.000000001611 61.0
CMS2_k127_1537165_43 COG0226 ABC-type phosphate transport system, periplasmic component - - - 0.00000002064 57.0
CMS2_k127_1537165_46 Belongs to the 'phage' integrase family - - - 0.00008326 45.0
CMS2_k127_1537165_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 6.882e-304 933.0
CMS2_k127_1537165_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 9.848e-293 900.0
CMS2_k127_1537165_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 3.707e-288 884.0
CMS2_k127_1537165_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.172e-280 862.0
CMS2_k127_1537165_9 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 4.416e-277 853.0
CMS2_k127_1546017_0 PFAM Retinal pigment epithelial membrane protein - - - 0.000000000000000000000000000000000000000000000000000000003683 222.0
CMS2_k127_1546017_1 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 GO:0005575,GO:0005576 1.3.3.11 0.000000000000000004195 91.0
CMS2_k127_1546017_2 CAAX protease self-immunity K07052 - - 0.0000000000000002151 82.0
CMS2_k127_1556143_0 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 388.0
CMS2_k127_1556143_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000009262 162.0
CMS2_k127_1599167_0 Nacht domain - - - 0.0000000000000000000000000000000000000000000007053 177.0
CMS2_k127_1599167_1 HEPN domain - - - 0.000000000000000000000000000004136 123.0
CMS2_k127_1599167_2 - - - - 0.000000000000000000309 91.0
CMS2_k127_1599167_4 - - - - 0.000229 51.0
CMS2_k127_1610339_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 426.0
CMS2_k127_1610339_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 289.0
CMS2_k127_1610339_2 homoserine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 248.0
CMS2_k127_1610339_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003165 249.0
CMS2_k127_1610339_4 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000000000000000000001462 171.0
CMS2_k127_1610339_5 LTXXQ motif family protein - - - 0.0000000000000000000000000000000000000004439 156.0
CMS2_k127_1650897_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1251.0
CMS2_k127_1650897_1 Participates in both transcription termination and antitermination K02600 - - 1.07e-306 942.0
CMS2_k127_1650897_2 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 2.708e-206 645.0
CMS2_k127_1650897_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 1.479e-199 623.0
CMS2_k127_1650897_4 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 510.0
CMS2_k127_1650897_5 dna polymerase iii K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 379.0
CMS2_k127_1650897_6 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 319.0
CMS2_k127_1650897_7 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 293.0
CMS2_k127_1650897_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008953 237.0
CMS2_k127_1687105_0 phosphate transporter K03306 - - 5.209e-309 950.0
CMS2_k127_1687105_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 3.829e-267 824.0
CMS2_k127_1687105_10 - - - - 0.000000000000000005013 83.0
CMS2_k127_1687105_2 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 601.0
CMS2_k127_1687105_3 PFAM Ion transport protein K08714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 505.0
CMS2_k127_1687105_4 TIGRFAM phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 456.0
CMS2_k127_1687105_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 438.0
CMS2_k127_1687105_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 430.0
CMS2_k127_1687105_7 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001785 274.0
CMS2_k127_1687105_8 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000000000000000000000000000000601 172.0
CMS2_k127_1687105_9 nitric oxide dioxygenase activity - - - 0.0000000000000000000000000000000000000000000002038 167.0
CMS2_k127_1710374_0 phosphonate metabolism protein PhnM K06162 - 3.6.1.63 3.855e-238 738.0
CMS2_k127_1710374_1 phosphonate C-P lyase system protein PhnK K05781 GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0071704,GO:1901575,GO:1902494,GO:1904176 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 552.0
CMS2_k127_1710374_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 549.0
CMS2_k127_1710374_3 Carbon-phosphorus lyase complex accessory protein K06167 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016787,GO:0016788,GO:0019634,GO:0019637,GO:0019700,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046434,GO:0046872,GO:0046914,GO:0071704,GO:1901575 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 511.0
CMS2_k127_1710374_4 phosphonate C-P lyase system protein PhnL K05780 GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0061694,GO:0061695,GO:0071704,GO:1901575,GO:1902494,GO:1990234 2.7.8.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 481.0
CMS2_k127_1710374_5 Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP) K05774 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006015,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019634,GO:0019637,GO:0019674,GO:0019693,GO:0033863,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046496,GO:0046835,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 285.0
CMS2_k127_1710374_6 Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose K06163 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016829,GO:0018835,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0098848,GO:1901575,GO:1902494,GO:1904176 4.7.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007369 273.0
CMS2_k127_1711475_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1362.0
CMS2_k127_1711475_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1011.0
CMS2_k127_1711475_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 500.0
CMS2_k127_1711475_3 Succinate dehydrogenase hydrophobic membrane anchor K00242 - - 0.00000000000000000000000000000000000000000000000000000000000001668 217.0
CMS2_k127_1711475_4 succinate dehydrogenase K00241 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000003077 207.0
CMS2_k127_1715323_0 Diguanylate cyclase - - - 0.0 1332.0
CMS2_k127_1715323_1 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.0 1146.0
CMS2_k127_1715323_2 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 588.0
CMS2_k127_1715323_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 307.0
CMS2_k127_1715323_4 Possibly involved in utilization of glycolate and propanediol - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 293.0
CMS2_k127_1715323_5 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000000000000000000000000000000000008372 184.0
CMS2_k127_1715323_6 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000001413 102.0
CMS2_k127_179059_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.0 1438.0
CMS2_k127_179059_1 PFAM Peptidase family U32 K08303 - - 0.0 1002.0
CMS2_k127_179059_10 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000002033 176.0
CMS2_k127_179059_11 PFAM L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000001052 162.0
CMS2_k127_179059_2 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.592e-296 913.0
CMS2_k127_179059_3 type I secretion outer membrane protein, TolC K12340,K12538 - - 6.549e-242 752.0
CMS2_k127_179059_4 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006785 548.0
CMS2_k127_179059_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 467.0
CMS2_k127_179059_6 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 388.0
CMS2_k127_179059_7 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 310.0
CMS2_k127_179059_8 DNA glycosylase K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002131 269.0
CMS2_k127_179059_9 CYTH K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000073 203.0
CMS2_k127_1791642_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 552.0
CMS2_k127_1791642_1 PFAM PepSY-associated TM helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 411.0
CMS2_k127_1791642_2 Peptidyl-prolyl cis-trans isomerase K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 396.0
CMS2_k127_1791642_3 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 370.0
CMS2_k127_1791642_4 Uncharacterized protein conserved in bacteria (DUF2058) K09912 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 300.0
CMS2_k127_1791642_5 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000002254 237.0
CMS2_k127_1791642_6 Protein with unknown function (DUF469) K09923 - - 0.000000000000000000000000000000000000000000000000000000000000002461 218.0
CMS2_k127_1791642_7 FMN_bind - - - 0.0000000000000000000000000000000000000000003938 159.0
CMS2_k127_1791642_8 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000001983 121.0
CMS2_k127_179850_0 sucrose phosphate synthase, sucrose phosphatase-like domain, bacterial K00696 - 2.4.1.14 0.0 1318.0
CMS2_k127_179850_1 DNA polymerase K03502 - - 4.051e-274 846.0
CMS2_k127_179850_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 1.469e-257 795.0
CMS2_k127_179850_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 472.0
CMS2_k127_179850_4 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 465.0
CMS2_k127_179850_5 Belongs to the peptidase S24 family K03503 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 365.0
CMS2_k127_179850_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007565 258.0
CMS2_k127_179850_7 Belongs to the carbohydrate kinase PfkB family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000004171 218.0
CMS2_k127_1829083_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 5.972e-288 890.0
CMS2_k127_1829083_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 2.826e-270 834.0
CMS2_k127_1829083_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.482e-224 697.0
CMS2_k127_1829083_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 2.599e-209 653.0
CMS2_k127_1829083_4 Peptidoglycan polymerase that is essential for cell division K03588 - - 1.102e-205 644.0
CMS2_k127_1829083_5 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 342.0
CMS2_k127_1829083_6 KR domain K00034 - 1.1.1.47 0.00003744 48.0
CMS2_k127_1946358_0 Phage terminase, large subunit K06909 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 415.0
CMS2_k127_2038387_0 chemotaxis, protein K03406,K03776 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0009453,GO:0009454,GO:0009605,GO:0009987,GO:0016020,GO:0023052,GO:0040011,GO:0042221,GO:0042330,GO:0042802,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0050918,GO:0051716,GO:0052128,GO:0052131,GO:0065007,GO:0071944 - 0.0 1230.0
CMS2_k127_2038387_2 Belongs to the UPF0061 (SELO) family K08997 - - 0.0000000000000000000000000000000000000000000000000193 179.0
CMS2_k127_2050402_0 TIGRFAM aminopeptidase N, Escherichia coli type K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 537.0
CMS2_k127_2050402_1 peptidoglycan biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 467.0
CMS2_k127_2063313_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.35e-259 802.0
CMS2_k127_2063313_1 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 2.004e-257 796.0
CMS2_k127_2063313_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 601.0
CMS2_k127_2063313_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 526.0
CMS2_k127_2063313_4 Protein of unknown function, DUF484 K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 443.0
CMS2_k127_2063313_5 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 353.0
CMS2_k127_2063313_6 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 332.0
CMS2_k127_2063313_7 Protein of unknown function (DUF971) - - - 0.0000000000000000009219 85.0
CMS2_k127_2076201_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1015.0
CMS2_k127_2076201_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.446e-271 838.0
CMS2_k127_2076201_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 6.927e-195 612.0
CMS2_k127_2076201_3 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 565.0
CMS2_k127_2076201_4 PFAM Response regulator receiver domain K07689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 396.0
CMS2_k127_2076201_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 393.0
CMS2_k127_2093097_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 9.161e-253 780.0
CMS2_k127_2093097_1 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 324.0
CMS2_k127_209653_0 GtrA-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 412.0
CMS2_k127_209653_1 PFAM DTW domain containing protein K05812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 289.0
CMS2_k127_209653_2 -acetyltransferase - - - 0.0000000000000000000000000000000283 131.0
CMS2_k127_2105858_0 FAD linked oxidases, C-terminal domain - - - 1.03e-306 942.0
CMS2_k127_2105858_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 3.164e-240 743.0
CMS2_k127_2105858_2 FAD binding domain - - - 8.819e-213 662.0
CMS2_k127_2105858_3 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000002184 100.0
CMS2_k127_2105858_4 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000009183 68.0
CMS2_k127_2128779_0 Bacteriophage Lambda NinG protein - - - 0.00000000000000000000000000000000003453 140.0
CMS2_k127_2128779_1 - - - - 0.0002577 53.0
CMS2_k127_2129311_0 RNA pseudouridylate synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007617 414.0
CMS2_k127_2129311_1 FAD-dependent dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 376.0
CMS2_k127_2129311_2 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 368.0
CMS2_k127_2129311_3 CRISPR-associated protein, APE2256 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 278.0
CMS2_k127_2129311_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006814 265.0
CMS2_k127_2129311_5 LPP20 lipoprotein - - - 0.00000000000000000000000000000000000000000000000002234 192.0
CMS2_k127_2159933_0 NMT1-like family K02051 - - 1.076e-205 640.0
CMS2_k127_2159933_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 516.0
CMS2_k127_2159933_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 496.0
CMS2_k127_2159933_3 Xylose isomerase - - - 0.000000000000000000000000000002465 120.0
CMS2_k127_2159933_4 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.0000000000000000000000000002664 113.0
CMS2_k127_2161033_0 synthase K01641,K15311 - 2.3.3.10 1.04e-243 754.0
CMS2_k127_2161033_1 GHMP kinases N terminal domain K00869 - 2.7.1.36 1.795e-209 653.0
CMS2_k127_2161033_2 GHMP kinases N terminal domain K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 555.0
CMS2_k127_2161033_3 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 404.0
CMS2_k127_2161033_4 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 331.0
CMS2_k127_2161281_0 Putative diguanylate phosphodiesterase - - - 0.0 1279.0
CMS2_k127_2161281_1 DUF1704 - - - 0.0 1223.0
CMS2_k127_2161281_10 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K03796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 378.0
CMS2_k127_2161281_11 Putative ATP-dependant zinc protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001162 255.0
CMS2_k127_2161281_12 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000002208 144.0
CMS2_k127_2161281_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000001468 103.0
CMS2_k127_2161281_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0008703 43.0
CMS2_k127_2161281_2 Domain of unknown function DUF21 - - - 5.583e-274 846.0
CMS2_k127_2161281_3 Acts as a magnesium transporter K06213 - - 8.924e-262 810.0
CMS2_k127_2161281_4 Succinylglutamate desuccinylase aspartoacylase K06987 - - 3.427e-209 653.0
CMS2_k127_2161281_5 mechanosensitive ion channel - - - 3.677e-199 625.0
CMS2_k127_2161281_6 Belongs to the RimK family K05844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 587.0
CMS2_k127_2161281_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 551.0
CMS2_k127_2161281_8 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008408 452.0
CMS2_k127_2161281_9 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 452.0
CMS2_k127_2186957_0 Diguanylate cyclase K21023 - 2.7.7.65 0.0 1056.0
CMS2_k127_2186957_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 447.0
CMS2_k127_2189794_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1348.0
CMS2_k127_2189794_1 Thioredoxin-like - - - 5.628e-197 621.0
CMS2_k127_2189794_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 484.0
CMS2_k127_2198812_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1169.0
CMS2_k127_2198812_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 2.051e-301 925.0
CMS2_k127_2198812_2 C4-dicarboxylate transporter malic acid transport protein K03304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 297.0
CMS2_k127_2198812_3 Voltage-dependent anion channel - - - 0.0000000000000000000000000000000000000000000000000009051 187.0
CMS2_k127_2198812_4 - - - - 0.0000000005986 61.0
CMS2_k127_2198812_5 - - - - 0.000000005986 59.0
CMS2_k127_2239260_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 6.737e-289 890.0
CMS2_k127_2239260_1 Permease YjgP YjgQ K07091 - - 5.452e-203 636.0
CMS2_k127_2239260_2 Permease YjgP YjgQ K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 589.0
CMS2_k127_2244933_0 NMT1-like family K15576 - - 3.878e-297 912.0
CMS2_k127_2244933_1 Glycosyl transferases group 1 - - - 1.892e-250 776.0
CMS2_k127_2244933_10 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000003504 223.0
CMS2_k127_2244933_11 - - - - 0.0000000000000000000000000000000000000000000000000000009235 192.0
CMS2_k127_2244933_12 NMT1-like family K22067 - - 0.0000000000000000000000000000000000000000000000000002803 185.0
CMS2_k127_2244933_13 DNA-binding protein VF530 - - - 0.0000000000000000000000000000000000000000000004056 168.0
CMS2_k127_2244933_2 TIGRFAM Diguanylate cyclase - - - 3.298e-237 737.0
CMS2_k127_2244933_3 transporter, permease K15577 - - 1.026e-202 632.0
CMS2_k127_2244933_4 TIGRFAM Nitrate transport ATP-binding K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 520.0
CMS2_k127_2244933_5 NMT1-like family K22067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 502.0
CMS2_k127_2244933_6 General glycosylation pathway protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 495.0
CMS2_k127_2244933_7 PFAM response regulator receiver K07183 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 351.0
CMS2_k127_2244933_8 response regulator K07183 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000419 343.0
CMS2_k127_2249688_0 diguanylate cyclase - - - 3.35e-266 827.0
CMS2_k127_2249688_1 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 600.0
CMS2_k127_2270180_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000002985 223.0
CMS2_k127_2270180_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000004101 203.0
CMS2_k127_2277486_0 ABC transporter K06158 - - 1.197e-317 974.0
CMS2_k127_2277486_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.299e-259 803.0
CMS2_k127_2277486_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 481.0
CMS2_k127_2277486_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 396.0
CMS2_k127_2277486_4 COG0607 Rhodanese-related sulfurtransferase - - - 0.00000000000000000000000000000003082 126.0
CMS2_k127_2279118_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 1.986e-262 811.0
CMS2_k127_2279118_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 379.0
CMS2_k127_2279118_2 Belongs to the Orn Lys Arg decarboxylase class-II family K01581,K01586 - 4.1.1.17,4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000836 299.0
CMS2_k127_2279118_3 PFAM OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004843 265.0
CMS2_k127_2279118_4 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000004449 232.0
CMS2_k127_2279118_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000505 87.0
CMS2_k127_2279118_6 - - - - 0.00000000004998 64.0
CMS2_k127_2299058_0 Mechanosensitive ion channel K05802 - - 0.0 1067.0
CMS2_k127_2299058_1 Sodium:alanine symporter family K03310 - - 3.749e-267 825.0
CMS2_k127_2299058_2 Serine dehydratase beta chain K01752 - 4.3.1.17 7.586e-262 812.0
CMS2_k127_2299058_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 2.499e-221 691.0
CMS2_k127_2299058_4 member of the haloacid dehalogenase-like hydrolases superfamily and Cof family of proteins - GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050308 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 469.0
CMS2_k127_2299058_5 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 464.0
CMS2_k127_2299058_6 Cytochrome B561 K12262 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000925 336.0
CMS2_k127_2299058_7 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 305.0
CMS2_k127_2305963_0 ABC transporter transmembrane region K06148 - - 0.0 1143.0
CMS2_k127_2305963_1 Fatty acid desaturase - - - 6.732e-194 607.0
CMS2_k127_2305963_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 559.0
CMS2_k127_2305963_3 Metallo-beta-lactamase superfamily K13075 - 3.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 506.0
CMS2_k127_2305963_4 Hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008116 505.0
CMS2_k127_2305963_5 PFAM Glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 405.0
CMS2_k127_2305963_6 Xylose isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 347.0
CMS2_k127_2305963_7 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000002313 203.0
CMS2_k127_2305963_8 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 0.00000000000000000000000001494 108.0
CMS2_k127_2305963_9 - - - - 0.00000000000000000000000004205 111.0
CMS2_k127_2311794_0 Terminase RNaseH-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003201 288.0
CMS2_k127_2311794_1 - - - - 0.00000000000000000000000000001147 121.0
CMS2_k127_2311794_2 AIG2-like family - - - 0.0000000000000000000000005708 109.0
CMS2_k127_2311794_3 Putative amidoligase enzyme - - - 0.0000000000000001323 92.0
CMS2_k127_2311794_4 - - - - 0.00000004773 59.0
CMS2_k127_2311794_5 RTX toxin acyltransferase family K07389 - - 0.0000003718 58.0
CMS2_k127_2311794_6 Sigma-54 interaction domain - - - 0.0008077 46.0
CMS2_k127_2327854_0 His Kinase A (phosphoacceptor) domain - - - 2.959e-296 913.0
CMS2_k127_2327854_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 2.354e-290 896.0
CMS2_k127_2327854_2 Gentisate 1,2-dioxygenase - - - 1.027e-202 631.0
CMS2_k127_2327854_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 568.0
CMS2_k127_2327854_4 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 466.0
CMS2_k127_2327854_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004302 237.0
CMS2_k127_2327854_6 arsenate reductase K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000006061 205.0
CMS2_k127_2327854_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000000000001135 105.0
CMS2_k127_2327854_8 domain, Protein K03112 - - 0.00000000009848 61.0
CMS2_k127_2369126_0 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 591.0
CMS2_k127_2369126_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 398.0
CMS2_k127_2369126_2 cell adhesion involved in biofilm formation K12287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 320.0
CMS2_k127_2369126_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001814 235.0
CMS2_k127_2369126_4 - - - - 0.000004367 48.0
CMS2_k127_2369126_5 - - - - 0.00001591 47.0
CMS2_k127_2381954_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 5.376e-215 668.0
CMS2_k127_2381954_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 397.0
CMS2_k127_2381954_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000001714 97.0
CMS2_k127_2391263_0 PFAM FAD dependent oxidoreductase K00116 - 1.1.5.4 8.524e-283 869.0
CMS2_k127_2391263_1 Major Facilitator Superfamily - - - 1.794e-226 704.0
CMS2_k127_2391263_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 2.834e-212 660.0
CMS2_k127_2391263_3 Sulphur transport K07112 - - 3.835e-207 646.0
CMS2_k127_2391263_4 FolM Alternative dihydrofolate reductase 1 K13938 - 1.5.1.3,1.5.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 428.0
CMS2_k127_2391263_5 PFAM Bacterial regulatory protein, arsR family K03892 - - 0.0000000000000000000000000000000000000000000000000003267 186.0
CMS2_k127_2393795_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1637.0
CMS2_k127_2393795_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1146.0
CMS2_k127_2393795_2 LVIVD repeat - - - 5.149e-261 836.0
CMS2_k127_2393795_3 Belongs to the aspartokinase family K00928 - 2.7.2.4 8.345e-254 784.0
CMS2_k127_2393795_4 cell adhesion involved in biofilm formation K12287 - - 4.794e-247 790.0
CMS2_k127_2393795_5 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 1.546e-209 652.0
CMS2_k127_2393795_6 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 343.0
CMS2_k127_2393795_7 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 286.0
CMS2_k127_2429446_0 twitching motility protein PilT K02669 - - 5.64e-206 642.0
CMS2_k127_2429446_1 Chain length determinant protein K05789 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 323.0
CMS2_k127_2429446_2 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006692 256.0
CMS2_k127_2445946_0 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 3.542e-267 827.0
CMS2_k127_2445946_1 Cell wall formation K00075 - 1.3.1.98 1.413e-220 685.0
CMS2_k127_2445946_2 Mechanosensitive ion channel K16052 - - 3.449e-219 683.0
CMS2_k127_2445946_3 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.00000000000000000000000000000000000000003707 151.0
CMS2_k127_2485445_0 cell division protein K03466 - - 8.281e-199 625.0
CMS2_k127_2485445_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 405.0
CMS2_k127_2531959_0 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 561.0
CMS2_k127_2531959_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 364.0
CMS2_k127_2630149_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0 1536.0
CMS2_k127_2630149_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 9.358e-266 820.0
CMS2_k127_2630149_10 haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K01091 - 3.1.3.18 0.00000000000000000000000000000002416 126.0
CMS2_k127_2630149_2 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 5.316e-205 638.0
CMS2_k127_2630149_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 463.0
CMS2_k127_2630149_5 RNA pseudouridylate synthase K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 411.0
CMS2_k127_2630149_6 Low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 322.0
CMS2_k127_2630149_7 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 319.0
CMS2_k127_2630149_8 ACT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 312.0
CMS2_k127_2630149_9 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000001087 204.0
CMS2_k127_2687987_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 1.114e-240 745.0
CMS2_k127_2687987_1 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 602.0
CMS2_k127_2687987_2 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 284.0
CMS2_k127_2692172_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 2494.0
CMS2_k127_2692172_1 Belongs to the 5'-nucleotidase family K17224 - - 0.0 1249.0
CMS2_k127_2692172_2 PFAM PhoH-like protein K07175 - - 6.032e-300 921.0
CMS2_k127_2692172_3 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K18800 - - 1.234e-256 796.0
CMS2_k127_2692172_4 NlpB/DapX lipoprotein - - - 3.271e-219 682.0
CMS2_k127_2692172_5 LysR substrate binding domain - - - 8.185e-201 626.0
CMS2_k127_2692172_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 557.0
CMS2_k127_2692172_7 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 425.0
CMS2_k127_2692172_8 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 306.0
CMS2_k127_2692172_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000001217 265.0
CMS2_k127_2703517_0 regulator of chromosome condensation, RCC1 - - - 0.0 1037.0
CMS2_k127_2703517_1 ABC transporter transmembrane region K12541 - - 3.766e-251 794.0
CMS2_k127_2703517_2 Sulfotransferase domain - - - 6.268e-238 746.0
CMS2_k127_2703517_3 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 602.0
CMS2_k127_2703517_4 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 474.0
CMS2_k127_2703517_5 Biotin-lipoyl like K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 477.0
CMS2_k127_2703517_6 Outer membrane efflux protein K12543 - - 0.00000000000000000000000000000000000000000000000000000000000000000003473 248.0
CMS2_k127_2703517_7 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000859 191.0
CMS2_k127_2703719_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1512.0
CMS2_k127_2703719_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000001151 222.0
CMS2_k127_2703719_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000000000000171 171.0
CMS2_k127_270688_0 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0 1050.0
CMS2_k127_270688_1 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 601.0
CMS2_k127_270688_2 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 499.0
CMS2_k127_270688_3 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000002782 217.0
CMS2_k127_2753640_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1324.0
CMS2_k127_2753640_1 Peptidase M16C associated K06972 - - 0.0 1094.0
CMS2_k127_2753640_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000000000000007497 163.0
CMS2_k127_2775291_0 Major Facilitator Superfamily - - - 1.395e-258 799.0
CMS2_k127_2775291_1 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 476.0
CMS2_k127_2775291_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 398.0
CMS2_k127_2775291_3 Sulphur transport - - - 0.000000000000000000000003435 102.0
CMS2_k127_2792799_0 Amino acid kinase family K00928 - 2.7.2.4 1.997e-305 938.0
CMS2_k127_2792799_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 2.655e-266 821.0
CMS2_k127_2792799_2 DnaJ molecular chaperone homology domain K05801 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 472.0
CMS2_k127_2792799_3 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 406.0
CMS2_k127_2792799_4 L-2,4-diaminobutyric acid acetyltransferase K06718 - 2.3.1.178 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 364.0
CMS2_k127_2792799_5 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006584 269.0
CMS2_k127_2792799_6 Low affinity iron permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001773 240.0
CMS2_k127_2792799_7 - - - - 0.00000000000000000000000000000000000000003567 155.0
CMS2_k127_280390_0 Zn-dependent protease with chaperone function - - - 1.627e-212 678.0
CMS2_k127_284827_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1374.0
CMS2_k127_284827_1 dihydroorotase K01465 - 3.5.2.3 5.494e-293 899.0
CMS2_k127_284827_2 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000009481 231.0
CMS2_k127_284827_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000000000000000001778 154.0
CMS2_k127_2869518_0 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 2.355e-304 938.0
CMS2_k127_2869518_1 His Kinase A (phosphoacceptor) domain - - - 5.486e-256 796.0
CMS2_k127_2869518_2 Protein of unknown function (DUF3616) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 535.0
CMS2_k127_2869518_3 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000471 400.0
CMS2_k127_2869518_4 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 289.0
CMS2_k127_2912428_0 D-isomer specific 2-hydroxyacid dehydrogenase K03778 - 1.1.1.28 1.027e-196 615.0
CMS2_k127_2912428_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000001532 135.0
CMS2_k127_2912428_2 Iron-regulated protein - - - 0.00000000000001759 73.0
CMS2_k127_294768_0 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 7.971e-313 960.0
CMS2_k127_294768_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.83e-264 815.0
CMS2_k127_294768_2 Oxidoreductase NAD-binding domain K00380 - 1.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 600.0
CMS2_k127_3051783_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 3.359e-305 936.0
CMS2_k127_3051783_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 3.065e-201 629.0
CMS2_k127_3051783_10 MatE K03327 - - 0.0000000000000000000000000000000000000007295 148.0
CMS2_k127_3051783_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001792 128.0
CMS2_k127_3051783_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 551.0
CMS2_k127_3051783_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 437.0
CMS2_k127_3051783_4 TIGRFAM nudix-type nucleoside diphosphatase, YffH AdpP family K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 392.0
CMS2_k127_3051783_5 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001782 278.0
CMS2_k127_3051783_6 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004029 273.0
CMS2_k127_3051783_7 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001218 251.0
CMS2_k127_3051783_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000000000000000003551 196.0
CMS2_k127_3051783_9 Lipopolysaccharide assembly protein A domain K08992 - - 0.0000000000000000000000000000000000000000000000008489 177.0
CMS2_k127_3065159_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0 1235.0
CMS2_k127_3065159_1 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 535.0
CMS2_k127_3065159_2 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 389.0
CMS2_k127_3065159_3 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 381.0
CMS2_k127_3065159_4 Peptidase S24-like K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 302.0
CMS2_k127_3065159_5 Asparaginase, N-terminal K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009292 286.0
CMS2_k127_3065159_6 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000001236 245.0
CMS2_k127_3065159_7 PFAM YCII-related K09780 - - 0.00000000000000000000000000000000000000000000000000002909 188.0
CMS2_k127_3065159_8 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000001007 110.0
CMS2_k127_308652_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003188 290.0
CMS2_k127_308652_1 Predicted membrane protein (DUF2238) - - - 0.0000000000000000000000000000000000000000000000000000006361 199.0
CMS2_k127_308652_2 Protein of unknown function (DUF3185) - - - 0.00000000000000000000000000000005782 125.0
CMS2_k127_308652_3 Transglycosylase associated protein - - - 0.00000000000000000002347 92.0
CMS2_k127_30889_0 Elongation factor P (EF-P) OB domain K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 361.0
CMS2_k127_30889_1 (GGDEF) domain K20966 GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007 3.1.4.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 304.0
CMS2_k127_30889_2 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000003652 137.0
CMS2_k127_309673_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0 1028.0
CMS2_k127_309673_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 2.124e-200 627.0
CMS2_k127_309673_2 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 559.0
CMS2_k127_309673_3 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 328.0
CMS2_k127_309673_4 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 297.0
CMS2_k127_309673_5 PFAM Rhodanese-like K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005154 267.0
CMS2_k127_309673_6 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000003018 131.0
CMS2_k127_309673_7 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0033218,GO:0042277,GO:0043167,GO:0043168,GO:0043295,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0055114,GO:0072341,GO:1900750,GO:1901681 - 0.000000000000000000000000000000002564 131.0
CMS2_k127_309673_8 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.00002073 48.0
CMS2_k127_3126653_0 Restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 509.0
CMS2_k127_3126653_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 492.0
CMS2_k127_3126653_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family K00558 - 2.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 447.0
CMS2_k127_3126653_3 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 409.0
CMS2_k127_3126653_4 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008407 247.0
CMS2_k127_3126653_5 May nick specific sequences that contain T G mispairs resulting from m5C-deamination - - - 0.00000000000000000000000000000001254 129.0
CMS2_k127_3126653_6 Virulence protein RhuM family - - - 0.00000000000838 68.0
CMS2_k127_3126653_7 - - - - 0.000000008027 68.0
CMS2_k127_3126653_8 May nick specific sequences that contain T G mispairs resulting from m5C-deamination K07458 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0043170,GO:0043765,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0005948 42.0
CMS2_k127_3139706_0 DHH family K07462 - - 0.0 1132.0
CMS2_k127_3139706_1 AAA domain K07028 - - 3.563e-286 884.0
CMS2_k127_3139706_2 PFAM Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 481.0
CMS2_k127_3139706_3 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 475.0
CMS2_k127_3139706_4 Carbohydrate kinase, FGGY K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 362.0
CMS2_k127_3139706_6 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 354.0
CMS2_k127_3139706_7 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002732 272.0
CMS2_k127_3139706_8 type III effector - - - 0.00000000000000000000000000000000000000000000000000001857 190.0
CMS2_k127_3158430_0 PFAM Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 3.18e-289 889.0
CMS2_k127_3158430_1 Domain of unknown function (DUF4478) K06966 - 3.2.2.10 1.522e-288 887.0
CMS2_k127_3158430_2 Belongs to the DEAD box helicase family K05590 - 3.6.4.13 3.83e-252 779.0
CMS2_k127_3158430_3 HDOD domain - - - 2.327e-230 716.0
CMS2_k127_3158430_4 AI-2E family transporter - - - 2.078e-202 633.0
CMS2_k127_3158430_5 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 5.122e-201 627.0
CMS2_k127_3158430_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 586.0
CMS2_k127_3158430_7 Etoposide-induced protein 2.4 (EI24) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 459.0
CMS2_k127_3158430_8 PFAM CobW HypB UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000007564 160.0
CMS2_k127_3170450_0 PFAM polysaccharide export protein K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 535.0
CMS2_k127_3170450_1 G-rich domain on putative tyrosine kinase - - - 0.000000000000000000000000000000000000000001063 170.0
CMS2_k127_3178713_0 Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007532 278.0
CMS2_k127_3178713_1 Ankyrin repeats (3 copies) K06867 - - 0.000000000002064 79.0
CMS2_k127_3178713_2 transcriptional regulator - - - 0.0003245 43.0
CMS2_k127_3240285_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1978.0
CMS2_k127_3240285_1 Large exoproteins involved in heme utilization or adhesion - - - 0.0 1217.0
CMS2_k127_3240285_2 PFAM Surface antigen K07278 - - 0.0 1027.0
CMS2_k127_3240285_3 Belongs to the UPF0176 family K07146 - - 3.898e-200 625.0
CMS2_k127_3240285_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 421.0
CMS2_k127_3240285_5 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 370.0
CMS2_k127_3240285_6 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000001339 79.0
CMS2_k127_3241849_0 Mechanosensitive ion channel K05802 - - 5.138e-245 761.0
CMS2_k127_3241849_1 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 291.0
CMS2_k127_3241849_2 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000001277 171.0
CMS2_k127_3265401_0 PFAM Formylglycine-generating sulfatase enzyme - - - 5.879e-320 981.0
CMS2_k127_3265401_1 PFAM Aminotransferase class I and II K14155 - 4.4.1.8 5.048e-194 611.0
CMS2_k127_3265401_2 Putative 2OG-Fe(II) oxygenase - - - 0.0000000000000000009908 90.0
CMS2_k127_3277332_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 4.407e-233 723.0
CMS2_k127_3277332_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 416.0
CMS2_k127_3277332_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 313.0
CMS2_k127_329490_0 Glutamine amidotransferase domain K22081 - 2.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 522.0
CMS2_k127_329490_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 375.0
CMS2_k127_329490_2 Glutamate synthase K22082 - 2.1.1.21 0.000000000003538 66.0
CMS2_k127_3304045_0 Mo-co oxidoreductase dimerisation domain K17225 - - 1.089e-304 935.0
CMS2_k127_3304045_1 Belongs to the ALAD family K01698 - 4.2.1.24 5.385e-206 642.0
CMS2_k127_3304045_11 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000005253 151.0
CMS2_k127_3304045_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 606.0
CMS2_k127_3304045_3 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 557.0
CMS2_k127_3304045_4 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 546.0
CMS2_k127_3304045_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 536.0
CMS2_k127_3304045_6 Bacterial transferase hexapeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 338.0
CMS2_k127_3304045_7 Molybdenum cofactor biosynthesis protein MoaE K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 312.0
CMS2_k127_3304045_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000002911 215.0
CMS2_k127_3340632_0 FAD-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 319.0
CMS2_k127_3340632_1 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000000000161 222.0
CMS2_k127_3340632_2 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000000000000000000005106 175.0
CMS2_k127_3343078_0 Sulfotransferase domain K13472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009947 440.0
CMS2_k127_3343078_1 outer membrane autotransporter barrel domain - - - 0.00000000000000000000000000000000000000000000000000000006633 208.0
CMS2_k127_3358860_0 7TM diverse intracellular signalling - - - 3.059e-233 732.0
CMS2_k127_3358860_1 - - - - 2.361e-227 707.0
CMS2_k127_3358860_10 Belongs to the 'phage' integrase family - - - 0.000001866 52.0
CMS2_k127_3358860_11 metallopeptidase activity K01179 - 3.2.1.4 0.000005071 50.0
CMS2_k127_3358860_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007515 368.0
CMS2_k127_3358860_3 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000755 277.0
CMS2_k127_3358860_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009241 243.0
CMS2_k127_3358860_5 Diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000001471 237.0
CMS2_k127_3358860_6 - - - - 0.00000000000000000000000000000000000000006092 152.0
CMS2_k127_3358860_7 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000001533 159.0
CMS2_k127_3358860_8 Diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000003042 150.0
CMS2_k127_3358860_9 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000007956 130.0
CMS2_k127_3371601_0 ABC transporter K15738 - - 0.0 1251.0
CMS2_k127_3371601_1 NADPH quinone reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 416.0
CMS2_k127_3371601_2 Spermidine synthase K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 387.0
CMS2_k127_3371601_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005339 253.0
CMS2_k127_3371601_4 Mitomycin resistance protein - - - 0.000000000000000000000000000000000000000000000004381 173.0
CMS2_k127_3387157_0 Carbohydrate kinase, FGGY K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 485.0
CMS2_k127_3387157_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006019 368.0
CMS2_k127_3409011_0 PhoH-like protein K06217 - - 9.246e-217 674.0
CMS2_k127_3409011_1 CBS domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 534.0
CMS2_k127_3409011_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007866 436.0
CMS2_k127_3409011_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 362.0
CMS2_k127_3409011_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 290.0
CMS2_k127_3410631_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.352e-259 799.0
CMS2_k127_3410631_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 7.295e-241 747.0
CMS2_k127_3410631_2 nitrogen regulation protein NR(I) K07712 - - 5.2e-219 680.0
CMS2_k127_3410631_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 586.0
CMS2_k127_3410631_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 485.0
CMS2_k127_3410631_5 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 455.0
CMS2_k127_3410631_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 320.0
CMS2_k127_3410631_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 317.0
CMS2_k127_3410631_8 nitrogen regulatory protein P-II K04752 - - 0.00000000000000000000000000000000000000000000000000000000000000001038 224.0
CMS2_k127_3410631_9 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000008181 201.0
CMS2_k127_3411271_0 class II (D, K and N) K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 578.0
CMS2_k127_3411271_1 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 361.0
CMS2_k127_3411271_2 TIGRFAM KamA family protein K19810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008007 267.0
CMS2_k127_3425425_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 6.64e-232 720.0
CMS2_k127_3425425_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 576.0
CMS2_k127_3425425_2 Peptidyl-prolyl cis-trans isomerase K03774 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007898 269.0
CMS2_k127_3425425_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 - 6.3.1.5,6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000009227 244.0
CMS2_k127_3451122_0 MMPL family - - - 0.0 1163.0
CMS2_k127_3451122_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000003904 221.0
CMS2_k127_3452150_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07708 - 2.7.13.3 5.837e-222 689.0
CMS2_k127_3452150_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 456.0
CMS2_k127_3452150_2 iron ion homeostasis K03709,K04758,K09819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 339.0
CMS2_k127_3452150_3 nitrogen regulation protein NR(I) K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 318.0
CMS2_k127_3452150_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000106 250.0
CMS2_k127_3452150_5 - - - - 0.000000000000000000000000000000000000000001834 156.0
CMS2_k127_3459464_0 Alpha amylase, catalytic domain K00690 - 2.4.1.7 0.0 1132.0
CMS2_k127_3459464_1 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 1.208e-253 784.0
CMS2_k127_3459464_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 1.583e-200 630.0
CMS2_k127_3459464_3 COG1030 Membrane-bound serine protease (ClpP class) K07403 - - 4.058e-196 621.0
CMS2_k127_3459464_4 HAD-superfamily hydrolase, subfamily IIB K07026,K15918 - 2.7.1.31,3.1.3.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 488.0
CMS2_k127_3459464_5 PFAM SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 413.0
CMS2_k127_3459464_6 Fe-S-cluster oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000001309 189.0
CMS2_k127_3459464_7 - K06910 - - 0.0000000000000000000000000000000000000000131 155.0
CMS2_k127_3482253_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0 1108.0
CMS2_k127_3482253_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0 1056.0
CMS2_k127_3482253_10 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 506.0
CMS2_k127_3482253_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 460.0
CMS2_k127_3482253_12 Peptidase family M23 K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008719 407.0
CMS2_k127_3482253_13 - K07283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 405.0
CMS2_k127_3482253_14 Smr protein MutS2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000839 327.0
CMS2_k127_3482253_15 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 326.0
CMS2_k127_3482253_16 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002136 250.0
CMS2_k127_3482253_17 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000000000000000000007247 162.0
CMS2_k127_3482253_2 homoserine dehydrogenase K00003 - 1.1.1.3 1.226e-269 831.0
CMS2_k127_3482253_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.333e-269 831.0
CMS2_k127_3482253_4 PFAM Aminotransferase class I and II K14261 - - 2.606e-257 794.0
CMS2_k127_3482253_5 Threonine synthase K01733 - 4.2.3.1 1.399e-245 760.0
CMS2_k127_3482253_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 8.066e-240 748.0
CMS2_k127_3482253_7 Protein conserved in bacteria - - - 9.498e-210 656.0
CMS2_k127_3482253_8 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 1.018e-196 615.0
CMS2_k127_3482253_9 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 559.0
CMS2_k127_351098_0 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.0 1220.0
CMS2_k127_351098_1 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 524.0
CMS2_k127_351098_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 350.0
CMS2_k127_3514849_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 1.092e-220 685.0
CMS2_k127_3514849_1 Polysaccharide biosynthesis protein K15894,K17716 - 4.2.1.115,5.1.3.2 3.02e-210 654.0
CMS2_k127_3514849_2 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division K08306 - - 7.942e-195 614.0
CMS2_k127_3514849_3 Belongs to the bacterial flagellin family K02397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 559.0
CMS2_k127_3525397_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1667.0
CMS2_k127_3525397_1 PFAM Binding-protein-dependent transport system inner membrane component K02037 - - 0.0 1428.0
CMS2_k127_3525397_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 2.749e-304 933.0
CMS2_k127_3525397_3 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 599.0
CMS2_k127_3525397_4 tRNA (guanine-N7-)-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 452.0
CMS2_k127_3525397_5 nitrogen regulatory protein P-II K04752 - - 0.00000000000000000000000000000000000000000000000000000000000000008388 222.0
CMS2_k127_3525397_6 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000002764 129.0
CMS2_k127_3573923_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 2085.0
CMS2_k127_3573923_1 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 453.0
CMS2_k127_3573923_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007773 339.0
CMS2_k127_3575856_0 Aminotransferase K00812 - 2.6.1.1 5.716e-244 756.0
CMS2_k127_3575856_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004898 274.0
CMS2_k127_3575856_2 Exopolysaccharide biosynthesis protein YbjH - GO:0000271,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0071704,GO:1901576 - 0.00000000000000000000000000000002057 128.0
CMS2_k127_3579326_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 9.11e-255 786.0
CMS2_k127_3579326_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 6.655e-214 666.0
CMS2_k127_3579326_2 Iron--sulfur cluster insertion protein erpA K15724 - - 0.0000000000000000000000000000000000000000000000000000000000000001267 222.0
CMS2_k127_3614483_0 Leucine-rich repeat (LRR) protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 578.0
CMS2_k127_3614483_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 462.0
CMS2_k127_3614483_2 - - - - 0.00000000000000000000000000000000000000000000000000000000282 200.0
CMS2_k127_3614483_3 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000039 178.0
CMS2_k127_363514_0 Peptidase family M23 - - - 0.00000000000000000000000000000000000335 141.0
CMS2_k127_3641288_0 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 8.465e-210 654.0
CMS2_k127_3641288_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 1.356e-194 608.0
CMS2_k127_3641288_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 606.0
CMS2_k127_3641288_3 TIGRFAM dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 526.0
CMS2_k127_3641288_4 Belongs to the UPF0301 (AlgH) family K07735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 370.0
CMS2_k127_3641288_5 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 321.0
CMS2_k127_3641288_6 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003828 265.0
CMS2_k127_3641288_7 protein involved in response to NO K07234 - - 0.0000000000000000000000000000165 118.0
CMS2_k127_3644390_0 PFAM AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 423.0
CMS2_k127_3644390_1 protein conserved in bacteria K09978 - - 0.000000000000000000000000000000000000000000000000001586 184.0
CMS2_k127_3644390_2 protein secretion K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000001539 174.0
CMS2_k127_3644390_3 (Lipo)protein - - - 0.00000000000000000000000000002424 117.0
CMS2_k127_3647761_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0 1334.0
CMS2_k127_3647761_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 3.129e-230 718.0
CMS2_k127_3647761_2 PFAM Phosphotransferase enzyme family K07102 - 2.7.1.221 1.274e-211 659.0
CMS2_k127_3647761_3 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 3.289e-197 619.0
CMS2_k127_3647761_4 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 570.0
CMS2_k127_3647761_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 531.0
CMS2_k127_3647761_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 334.0
CMS2_k127_3647761_7 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 281.0
CMS2_k127_3665255_0 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 4.614e-217 688.0
CMS2_k127_3665255_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 8.318e-199 619.0
CMS2_k127_3665255_2 HPP family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 595.0
CMS2_k127_3665255_3 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 536.0
CMS2_k127_3665255_4 Belongs to the pseudouridine synthase RsuA family K06182,K06183 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.19,5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 488.0
CMS2_k127_3665255_5 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 444.0
CMS2_k127_3665255_6 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 408.0
CMS2_k127_3665255_7 2OG-Fe(II) oxygenase K07394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 400.0
CMS2_k127_3702742_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 562.0
CMS2_k127_3702742_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 416.0
CMS2_k127_3702742_2 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 324.0
CMS2_k127_3702742_4 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004371 243.0
CMS2_k127_3724990_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0 1139.0
CMS2_k127_3724990_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0 1016.0
CMS2_k127_3724990_10 Sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000000000000000000000000000000001864 212.0
CMS2_k127_3724990_11 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.00000000000000000000000000000006249 125.0
CMS2_k127_3724990_2 Acts as a magnesium transporter K06213 - - 4.999e-273 842.0
CMS2_k127_3724990_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 1.139e-248 767.0
CMS2_k127_3724990_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 2.518e-200 626.0
CMS2_k127_3724990_5 ABC transporter, ATP-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 478.0
CMS2_k127_3724990_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 473.0
CMS2_k127_3724990_7 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 389.0
CMS2_k127_3724990_8 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 321.0
CMS2_k127_3724990_9 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000000000000000000000000000000000007131 219.0
CMS2_k127_373458_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.125e-283 873.0
CMS2_k127_373458_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 1.922e-270 833.0
CMS2_k127_373458_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.452e-266 821.0
CMS2_k127_373458_3 Long-chain fatty acid transport protein K06076 - - 5.161e-241 749.0
CMS2_k127_373458_4 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 526.0
CMS2_k127_373458_5 NGG1p interacting factor 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 458.0
CMS2_k127_373458_6 PFAM Cytochrome C1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 411.0
CMS2_k127_373458_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009065 389.0
CMS2_k127_373458_8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 373.0
CMS2_k127_373458_9 Conserved region in glutamate synthase - - - 0.00003453 46.0
CMS2_k127_3748959_0 zinc metalloprotease K11749 - - 2.479e-258 801.0
CMS2_k127_3748959_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 462.0
CMS2_k127_3748959_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009982 457.0
CMS2_k127_3748959_3 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 429.0
CMS2_k127_3748959_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 342.0
CMS2_k127_3748959_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000002321 233.0
CMS2_k127_3803433_0 FtsX-like permease family K02004 - - 0.0 1414.0
CMS2_k127_3803433_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 426.0
CMS2_k127_3803433_2 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000002909 242.0
CMS2_k127_3803739_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1367.0
CMS2_k127_3803739_1 Part of a membrane complex involved in electron transport K03615 - - 0.0 1092.0
CMS2_k127_3803739_10 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 321.0
CMS2_k127_3803739_11 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000000003105 190.0
CMS2_k127_3803739_12 Part of a membrane complex involved in electron transport K03612 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0009279,GO:0016020,GO:0016491,GO:0016651,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000002686 183.0
CMS2_k127_3803739_13 antisigma factor binding K04749,K20978 - - 0.000000000000000000000000000000000000000002504 156.0
CMS2_k127_3803739_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 2.7e-310 954.0
CMS2_k127_3803739_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 2.504e-231 717.0
CMS2_k127_3803739_4 Part of a membrane complex involved in electron transport K03614 - - 9.839e-221 685.0
CMS2_k127_3803739_5 CorA-like Mg2+ transporter protein K16074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 553.0
CMS2_k127_3803739_6 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 461.0
CMS2_k127_3803739_7 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 422.0
CMS2_k127_3803739_8 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 377.0
CMS2_k127_3803739_9 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 348.0
CMS2_k127_3830548_0 S4 domain K14761 - - 0.00000000000000000001393 93.0
CMS2_k127_3830548_1 protein conserved in bacteria - - - 0.00000000005586 67.0
CMS2_k127_383206_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 2.322e-198 625.0
CMS2_k127_383206_1 TonB-dependent Receptor Plug K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 518.0
CMS2_k127_383206_2 Leucine-rich repeat (LRR) protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 384.0
CMS2_k127_383206_3 Pentapeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001122 244.0
CMS2_k127_3857127_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0 1136.0
CMS2_k127_3857127_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1118.0
CMS2_k127_3857127_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 2.125e-220 684.0
CMS2_k127_3857127_3 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002106 263.0
CMS2_k127_3857127_4 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000000000006995 139.0
CMS2_k127_3859197_0 Outer membrane protein beta-barrel family K02014 - - 0.0 1228.0
CMS2_k127_3859197_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain III K01835 - 5.4.2.2 0.0 1029.0
CMS2_k127_3859197_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 1.092e-224 698.0
CMS2_k127_3859197_3 molecular chaperone K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 561.0
CMS2_k127_3859197_4 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 532.0
CMS2_k127_3861633_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008036 547.0
CMS2_k127_3875588_0 His Kinase A (phosphoacceptor) domain - - - 4.563e-232 723.0
CMS2_k127_3875588_1 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 407.0
CMS2_k127_3875588_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 374.0
CMS2_k127_3875588_3 Glycosyl transferase - GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 298.0
CMS2_k127_3893199_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0 1283.0
CMS2_k127_3893199_1 CRISPR-associated protein, APE2256 family - - - 1.327e-244 761.0
CMS2_k127_3893199_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 581.0
CMS2_k127_3893199_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 499.0
CMS2_k127_3893199_4 (ABC) transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 410.0
CMS2_k127_3893199_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 351.0
CMS2_k127_3893199_6 RNA pseudouridylate synthase - - - 0.00000000000000000000000000000000000000000009175 160.0
CMS2_k127_3897329_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 3.098e-269 832.0
CMS2_k127_3897329_1 Belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 534.0
CMS2_k127_3897329_2 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 527.0
CMS2_k127_3897329_4 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 327.0
CMS2_k127_3897329_5 protein conserved in bacteria K09929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 303.0
CMS2_k127_3897329_6 SprA-related family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001832 284.0
CMS2_k127_3897329_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002621 235.0
CMS2_k127_3897329_8 regulatory protein, arsR - - - 0.0000000000000000000000000000000000000000000000000000000000001911 212.0
CMS2_k127_3897329_9 - K01179 - 3.2.1.4 0.000000000000000000000000000000000006985 139.0
CMS2_k127_3899941_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 469.0
CMS2_k127_3899941_1 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000001332 228.0
CMS2_k127_3905395_0 protein conserved in bacteria K21470 - - 7.934e-317 976.0
CMS2_k127_3905395_1 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001406 251.0
CMS2_k127_3962358_0 Terminase RNAseH like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 578.0
CMS2_k127_3962358_1 Protein of unknown function (DUF3383) - - - 0.0000000000000000000000000000000000000000000000251 188.0
CMS2_k127_3962358_3 Phage-associated protein, HI1409 family K09961 - - 0.0000000001561 73.0
CMS2_k127_3962358_4 Phage Mu protein F like protein - - - 0.000000000204 72.0
CMS2_k127_3962358_5 Uncharacterized protein conserved in bacteria (DUF2213) K09960 - - 0.000000001895 70.0
CMS2_k127_3962358_6 - - - - 0.0000005349 58.0
CMS2_k127_4052800_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0 1182.0
CMS2_k127_4052800_1 PFAM aminotransferase class-III K00819,K00821 - 2.6.1.11,2.6.1.13,2.6.1.17 1.736e-234 727.0
CMS2_k127_4052800_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 2.644e-202 630.0
CMS2_k127_4052800_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 1.739e-195 610.0
CMS2_k127_4052800_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 383.0
CMS2_k127_4052800_5 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000002087 262.0
CMS2_k127_4052800_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000000000000000001369 198.0
CMS2_k127_4052800_7 Zinc-finger domain - - - 0.00000000000000000000000000000000003125 135.0
CMS2_k127_4053966_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 533.0
CMS2_k127_4053966_1 - - - - 0.00000000000000001946 89.0
CMS2_k127_4071385_0 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 566.0
CMS2_k127_4071385_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007932 544.0
CMS2_k127_4071385_2 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 416.0
CMS2_k127_4071385_3 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000000000000000000000000000006717 192.0
CMS2_k127_4081985_0 Cysteine-rich CWC - - - 0.00000000000000005082 83.0
CMS2_k127_4091829_0 signal-transduction protein containing cAMP-binding and CBS domains K07238 - - 2.347e-291 904.0
CMS2_k127_4091829_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 581.0
CMS2_k127_4091829_10 PFAM Uncharacterised protein family (UPF0093) K08973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001279 250.0
CMS2_k127_4091829_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001062 234.0
CMS2_k127_4091829_2 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006485 575.0
CMS2_k127_4091829_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 480.0
CMS2_k127_4091829_4 pseudouridine synthase Rlu family protein K06177 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 417.0
CMS2_k127_4091829_5 Peptidoglycan-binding protein, CsiV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 409.0
CMS2_k127_4091829_6 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 305.0
CMS2_k127_4091829_7 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008934 303.0
CMS2_k127_4091829_8 Belongs to the UPF0260 family K09160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 286.0
CMS2_k127_4091829_9 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 283.0
CMS2_k127_4092012_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1692.0
CMS2_k127_4092012_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0 1211.0
CMS2_k127_4092012_12 - - - - 0.00000000001094 67.0
CMS2_k127_4092012_2 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 593.0
CMS2_k127_4092012_3 COG2200 FOG EAL domain K21973 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 421.0
CMS2_k127_4092012_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 362.0
CMS2_k127_4092012_6 Uncharacterized protein conserved in bacteria (DUF2141) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001215 236.0
CMS2_k127_4092012_7 - - - - 0.0000000000000000000000000000000000000001255 155.0
CMS2_k127_4092012_8 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - 0.000000000000000000000000000000000000002909 161.0
CMS2_k127_4092012_9 Transglycosylase associated protein - - - 0.0000000000000000000000000000165 118.0
CMS2_k127_4095562_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0 1010.0
CMS2_k127_4095562_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 3.185e-227 706.0
CMS2_k127_4095562_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.00000000000000000000000000000000000000000000000005494 178.0
CMS2_k127_4095562_11 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000000000000000000000000000000005306 172.0
CMS2_k127_4095562_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 2.795e-225 699.0
CMS2_k127_4095562_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 604.0
CMS2_k127_4095562_4 Glutathione S-transferase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 403.0
CMS2_k127_4095562_5 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000372 385.0
CMS2_k127_4095562_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008829 366.0
CMS2_k127_4095562_7 Sulphur transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005178 262.0
CMS2_k127_4095562_8 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006688 235.0
CMS2_k127_4095562_9 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000000000000000001354 204.0
CMS2_k127_4119966_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18303 - - 0.0 1846.0
CMS2_k127_4119966_1 Diguanylate cyclase - - - 0.0 1098.0
CMS2_k127_4119966_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 8.931e-279 859.0
CMS2_k127_4119966_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K18302 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 561.0
CMS2_k127_4119966_4 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 396.0
CMS2_k127_4119966_5 Domain of unknown function (DUF1949) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003806 274.0
CMS2_k127_4130139_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0 1148.0
CMS2_k127_4130139_1 Belongs to the peptidase S11 family K07258 - 3.4.16.4 3.501e-240 745.0
CMS2_k127_4130139_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 2.165e-218 680.0
CMS2_k127_4130139_3 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 544.0
CMS2_k127_4130139_4 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 503.0
CMS2_k127_4130139_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 359.0
CMS2_k127_4130139_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 329.0
CMS2_k127_4130139_7 Protein of unknown function (DUF493) K09158 - - 0.000000000000000000000000000000000000000000000000000004162 191.0
CMS2_k127_4130139_8 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0000000000000000000000000002905 120.0
CMS2_k127_4177272_0 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 0.0 1487.0
CMS2_k127_4177272_1 Beta-Casp domain K07576 - - 5.045e-289 889.0
CMS2_k127_4177272_2 AsmA family K07289 - - 2.322e-265 822.0
CMS2_k127_4177272_3 Involved in the biosynthesis of porphyrin-containing compound - - - 1.152e-232 722.0
CMS2_k127_4177272_4 PFAM Fructosamine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 552.0
CMS2_k127_4177272_5 PFAM YicC-like family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 495.0
CMS2_k127_4177272_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 398.0
CMS2_k127_4177272_7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000001046 243.0
CMS2_k127_422760_0 Outer membrane efflux protein - - - 7.058e-245 761.0
CMS2_k127_422760_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 424.0
CMS2_k127_4233662_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 1.715e-280 869.0
CMS2_k127_4233662_1 energy transducer activity K03832,K07261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 316.0
CMS2_k127_4233662_2 Fe-S metabolism associated domain K02426 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 279.0
CMS2_k127_4233662_3 biopolymer transport protein K03559 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000007947 74.0
CMS2_k127_4237872_0 chemotaxis, protein K03406 - - 0.0 1167.0
CMS2_k127_4237872_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 502.0
CMS2_k127_4237872_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 352.0
CMS2_k127_4238869_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 6.778e-204 635.0
CMS2_k127_4238869_1 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 436.0
CMS2_k127_4238869_2 Lipopolysaccharide-assembly - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 357.0
CMS2_k127_4247604_0 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 546.0
CMS2_k127_4247604_1 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 515.0
CMS2_k127_4247604_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 477.0
CMS2_k127_4247604_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 366.0
CMS2_k127_4247604_4 Transcriptional regulator K13643 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 282.0
CMS2_k127_4247604_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001078 266.0
CMS2_k127_4247604_6 Is able to transfer iron-sulfur clusters to apo- ferredoxin. Multiple cycles of 2Fe2S cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system K13628 - - 0.000000000000000000000000000000000000000000000000000000000000112 213.0
CMS2_k127_427054_0 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 449.0
CMS2_k127_427054_1 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001148 256.0
CMS2_k127_427054_2 Tryptophan-rich protein (DUF2389) - - - 0.000000000000000000003122 96.0
CMS2_k127_427054_3 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region K00275 - 1.4.3.5 0.00000000000001068 76.0
CMS2_k127_4281823_0 PFAM aminotransferase class-III K01845 - 5.4.3.8 3.799e-271 835.0
CMS2_k127_4281823_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 424.0
CMS2_k127_4281823_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 368.0
CMS2_k127_4281823_3 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 311.0
CMS2_k127_4281823_4 protein conserved in bacteria K09906 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0017185,GO:0018126,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0055114,GO:0071704,GO:0072580,GO:1901260,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000004464 229.0
CMS2_k127_4288241_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1533.0
CMS2_k127_4288241_1 TIGRFAM aminopeptidase N, Escherichia coli type K01256 - 3.4.11.2 0.0 1360.0
CMS2_k127_4288241_10 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 367.0
CMS2_k127_4288241_11 OmpA family K03640 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 313.0
CMS2_k127_4288241_2 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1270.0
CMS2_k127_4288241_3 THUMP - - - 1.711e-300 923.0
CMS2_k127_4288241_4 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 1.117e-282 875.0
CMS2_k127_4288241_5 PFAM pfkB family carbohydrate kinase K00846 - 2.7.1.3 8.838e-238 738.0
CMS2_k127_4288241_6 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 4.806e-219 687.0
CMS2_k127_4288241_7 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 4.657e-207 645.0
CMS2_k127_4288241_8 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 492.0
CMS2_k127_4288241_9 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 443.0
CMS2_k127_4290211_0 heavy metal translocating P-type ATPase K01533 - 3.6.3.4 0.0 1509.0
CMS2_k127_4290211_1 Putative diguanylate phosphodiesterase - - - 0.0 1227.0
CMS2_k127_4290211_10 imidazoleglycerol-phosphate dehydratase K01089,K01693 - 3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 395.0
CMS2_k127_4290211_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 389.0
CMS2_k127_4290211_13 FixH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 328.0
CMS2_k127_4290211_14 - K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 319.0
CMS2_k127_4290211_15 - K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 298.0
CMS2_k127_4290211_16 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000000000000000001009 233.0
CMS2_k127_4290211_17 cytochrome oxidase maturation protein cbb3-type - - - 0.00000000000000000000000000001287 119.0
CMS2_k127_4290211_2 GTP-binding protein TypA K06207 - - 0.0 1182.0
CMS2_k127_4290211_3 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 3.194e-315 966.0
CMS2_k127_4290211_4 TIGRFAM cytochrome c oxidase accessory protein FixG - - - 6.387e-311 953.0
CMS2_k127_4290211_5 Belongs to the peptidase S33 family K01259 - 3.4.11.5 2.1e-199 622.0
CMS2_k127_4290211_6 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 5.944e-196 611.0
CMS2_k127_4290211_7 TIGRFAM cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 572.0
CMS2_k127_4290211_8 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 419.0
CMS2_k127_4290211_9 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 405.0
CMS2_k127_4290467_0 Bacterial extracellular solute-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 328.0
CMS2_k127_4290467_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 303.0
CMS2_k127_4290467_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000126 228.0
CMS2_k127_4290467_3 Protein of unknown function (DUF2789) - - - 0.000000000000000000000000000000000209 132.0
CMS2_k127_4290467_4 Binding-protein-dependent transport system inner membrane component K02018 - - 0.000004367 48.0
CMS2_k127_4297533_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001039 270.0
CMS2_k127_4297533_1 - - - - 0.00000000000000000000000000000000000001233 152.0
CMS2_k127_4297533_2 - - - - 0.000000000000000000000000000000000001097 142.0
CMS2_k127_4298178_0 4-Oxalocrotonate decarboxylase K01617 - 4.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000002358 250.0
CMS2_k127_4298178_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000003055 235.0
CMS2_k127_4310330_0 CoA binding domain - - - 0.0 1251.0
CMS2_k127_4310330_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0 1114.0
CMS2_k127_4310330_10 Bacterial protein of unknown function (DUF924) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 323.0
CMS2_k127_4310330_11 Protein of unknown function (DUF938) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007711 279.0
CMS2_k127_4310330_12 Nucleoside 2-deoxyribosyltransferase YtoQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004767 268.0
CMS2_k127_4310330_13 Domain of unknown function (DUF4156) - - - 0.0000000000000000000000000000000000000000000000001552 178.0
CMS2_k127_4310330_14 Transglycosylase associated protein - - - 0.0000000000000000000000000000000000006513 140.0
CMS2_k127_4310330_2 PFAM AsmA family K07289 - - 3.492e-302 933.0
CMS2_k127_4310330_3 PFAM NADH flavin oxidoreductase NADH oxidase family K10680 - - 4.245e-219 681.0
CMS2_k127_4310330_4 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 2.386e-211 661.0
CMS2_k127_4310330_5 Amino Acid - - - 5.146e-206 646.0
CMS2_k127_4310330_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 464.0
CMS2_k127_4310330_7 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 405.0
CMS2_k127_4310330_8 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 391.0
CMS2_k127_4310330_9 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 342.0
CMS2_k127_431197_0 FecCD transport family K11708 - - 6.682e-266 821.0
CMS2_k127_431197_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 9.142e-251 777.0
CMS2_k127_431197_2 COG1108 ABC-type Mn2 Zn2 transport systems permease components K09819,K11606,K11709 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 527.0
CMS2_k127_431197_3 Belongs to the bacterial solute-binding protein 9 family K11707 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 499.0
CMS2_k127_431197_4 ABC transporter K11710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 488.0
CMS2_k127_431197_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000008435 242.0
CMS2_k127_431197_7 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K22405 - 1.6.3.4 0.0000000001914 63.0
CMS2_k127_431345_0 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 549.0
CMS2_k127_431345_2 Protein of unknown function DUF45 K07043 - - 0.000000001281 59.0
CMS2_k127_4315111_0 Methyl-accepting chemotaxis protein K03406 - - 0.0 1118.0
CMS2_k127_4315111_1 ABC 3 transport family K02075,K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 464.0
CMS2_k127_4315111_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 354.0
CMS2_k127_4315111_3 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 346.0
CMS2_k127_4315111_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 303.0
CMS2_k127_4319458_0 Diguanylate cyclase K21021,K21023 - 2.7.7.65 1.304e-295 911.0
CMS2_k127_4319458_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 5.101e-250 773.0
CMS2_k127_4319458_2 flagellar protein fliS K02422 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001365 275.0
CMS2_k127_4320906_0 Chemotaxis protein K03415 - - 1.086e-194 608.0
CMS2_k127_4320906_1 curli production assembly transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 571.0
CMS2_k127_4320906_2 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007914 391.0
CMS2_k127_4320906_3 PilZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 358.0
CMS2_k127_4320906_5 COG2747 Negative regulator of flagellin synthesis (anti-sigma28 factor) K02398 - - 0.000000000000000000000000000000000000000002626 156.0
CMS2_k127_4325655_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 471.0
CMS2_k127_4325655_1 Peptidyl-prolyl cis-trans isomerase K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 420.0
CMS2_k127_4325655_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 291.0
CMS2_k127_4325655_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000002176 195.0
CMS2_k127_4367183_0 Belongs to the beta-ketoacyl-ACP synthases family K00647,K09458 - 2.3.1.179,2.3.1.41 1.93e-258 797.0
CMS2_k127_4367183_1 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 405.0
CMS2_k127_4367183_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 378.0
CMS2_k127_4367183_3 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 358.0
CMS2_k127_4375158_0 Pilus formation protein N terminal region K02280 - - 5.325e-267 829.0
CMS2_k127_4375158_1 AAA domain K02282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 603.0
CMS2_k127_4375158_2 Flp pilus assembly protein CpaB K02279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 444.0
CMS2_k127_4423556_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1369.0
CMS2_k127_4423556_1 Belongs to the DegT DnrJ EryC1 family K19715 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 1.823e-252 779.0
CMS2_k127_4423556_10 Rhodanese-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 319.0
CMS2_k127_4423556_11 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 314.0
CMS2_k127_4423556_12 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000000001252 153.0
CMS2_k127_4423556_2 PFAM Iron-containing alcohol dehydrogenase K19714 GO:0003674,GO:0003824,GO:0004022,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.3.48 1.022e-234 726.0
CMS2_k127_4423556_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 3.788e-227 708.0
CMS2_k127_4423556_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 4.285e-221 687.0
CMS2_k127_4423556_5 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 565.0
CMS2_k127_4423556_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 494.0
CMS2_k127_4423556_7 Protein of unknown function (DUF1275) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 415.0
CMS2_k127_4423556_8 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 374.0
CMS2_k127_4423556_9 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003332 333.0
CMS2_k127_4440708_0 flagellar hook-associated protein K02396 - - 0.0 1087.0
CMS2_k127_4440708_1 Rod binding protein K02395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002431 256.0
CMS2_k127_4440708_2 Belongs to the bacterial flagellin family K02397 - - 0.0000000000000000000000000000000000000000000000000000000001196 204.0
CMS2_k127_4460960_0 PFAM multicopper oxidase, type 1 multicopper oxidase, type 2 multicopper oxidase, type 3 K08100 - 1.3.3.5 2.2e-253 784.0
CMS2_k127_4460960_1 Copper resistance protein B precursor (CopB) K07233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 439.0
CMS2_k127_4460960_2 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 398.0
CMS2_k127_4460960_3 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 284.0
CMS2_k127_447015_0 M61 glycyl aminopeptidase - - - 0.0 1180.0
CMS2_k127_447015_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 604.0
CMS2_k127_447015_2 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 417.0
CMS2_k127_447015_3 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 413.0
CMS2_k127_447015_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 342.0
CMS2_k127_447015_5 Voltage-dependent anion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 328.0
CMS2_k127_447015_6 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000004954 169.0
CMS2_k127_447015_7 Belongs to the SlyX family K03745 - - 0.000000000000000000000000000000000001139 139.0
CMS2_k127_4491646_0 Putative diguanylate phosphodiesterase - - - 0.0 1582.0
CMS2_k127_4494957_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 1.598e-232 723.0
CMS2_k127_4494957_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 462.0
CMS2_k127_4494957_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 437.0
CMS2_k127_4494957_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 377.0
CMS2_k127_4494957_4 FliG C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 286.0
CMS2_k127_4494957_5 FliG C-terminal domain K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008377 259.0
CMS2_k127_4494957_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000000000000000000003218 210.0
CMS2_k127_4494957_7 - - - - 0.00000000003503 70.0
CMS2_k127_4500148_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 1.249e-225 700.0
CMS2_k127_4500148_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004069 602.0
CMS2_k127_4500148_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 303.0
CMS2_k127_4500148_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 295.0
CMS2_k127_4508247_0 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 333.0
CMS2_k127_4508247_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 316.0
CMS2_k127_4508247_2 Protein of unknown function (DUF3465) - - - 0.00000000000000000000000000000000000000000000000000000000000001944 219.0
CMS2_k127_4508247_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000001515 100.0
CMS2_k127_4508247_4 - K01179 - 3.2.1.4 0.0000000000007804 73.0
CMS2_k127_4508247_5 Belongs to the Dps family K04047 - - 0.000000003721 57.0
CMS2_k127_4557046_0 Inositol monophosphatase family K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 527.0
CMS2_k127_4557046_1 Haloacid dehalogenase-like hydrolase K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 434.0
CMS2_k127_4557046_2 NUDIX domain K08312 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 337.0
CMS2_k127_4557046_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001456 281.0
CMS2_k127_4557046_4 HDOD domain - - - 0.000000000000000000000000000000000000000003659 165.0
CMS2_k127_4566906_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 2.578e-251 776.0
CMS2_k127_4566906_1 protein conserved in bacteria K03690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 368.0
CMS2_k127_4581298_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 321.0
CMS2_k127_4581298_1 response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 332.0
CMS2_k127_4581298_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 278.0
CMS2_k127_4581298_3 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001348 260.0
CMS2_k127_4588324_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 1.036e-289 891.0
CMS2_k127_4588324_1 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 470.0
CMS2_k127_4588324_2 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 449.0
CMS2_k127_4588324_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005829 281.0
CMS2_k127_4592479_0 domain, Protein K03112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 540.0
CMS2_k127_4592479_1 Belongs to the UPF0225 family K09858 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000305 250.0
CMS2_k127_4592479_2 MatE K03327 - - 0.000000000000000000000000000000001412 131.0
CMS2_k127_4598497_0 Cadherin repeats. - - - 0.0000000000000000000000000000004786 141.0
CMS2_k127_4598497_1 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000002583 139.0
CMS2_k127_4644098_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.0 1642.0
CMS2_k127_4644098_1 Cytochrome c-type biogenesis protein Ccs1 ResB K07399 - - 0.0 1267.0
CMS2_k127_4644098_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1209.0
CMS2_k127_4644098_3 TIGRFAM ATP-dependent DNA helicase, RecQ K03654 - 3.6.4.12 0.0 1179.0
CMS2_k127_4644098_4 Diguanylate cyclase phosphodiesterase - - - 4.636e-318 983.0
CMS2_k127_4644098_5 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 449.0
CMS2_k127_4644098_6 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 425.0
CMS2_k127_4653152_0 ABC transporter transmembrane region K12541 - - 0.0 1364.0
CMS2_k127_4653152_1 LapD/MoxY periplasmic domain - - - 0.0 1173.0
CMS2_k127_4653152_10 long-chain fatty acid transporting porin activity K09806 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000008877 148.0
CMS2_k127_4653152_2 magnesium chelatase K07391 - - 2.25e-306 942.0
CMS2_k127_4653152_3 TIGRFAM type I secretion membrane fusion protein, HlyD family K12542 - - 6.304e-264 816.0
CMS2_k127_4653152_4 TIGRFAM type I secretion outer membrane protein, TolC family K12543 - - 1.251e-233 728.0
CMS2_k127_4653152_5 diguanylate cyclase K13590 - 2.7.7.65 4.762e-200 626.0
CMS2_k127_4653152_6 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 432.0
CMS2_k127_4653152_7 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 382.0
CMS2_k127_4653152_8 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 349.0
CMS2_k127_4653152_9 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000003957 173.0
CMS2_k127_4665971_0 Glucose / Sorbosone dehydrogenase K21430 - - 3.764e-221 687.0
CMS2_k127_4665971_1 deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000001764 224.0
CMS2_k127_4677333_0 Isocitrate dehydrogenase NADP-dependent, monomeric type K00031 - 1.1.1.42 0.0 1324.0
CMS2_k127_4677333_1 Peptidylprolyl isomerase K03770 - 5.2.1.8 6.308e-312 961.0
CMS2_k127_4677333_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 3.159e-243 752.0
CMS2_k127_4677333_3 High frequency lysogenization protein hflD homolog K07153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 438.0
CMS2_k127_4677333_4 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 363.0
CMS2_k127_4677333_5 DNA-J related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 364.0
CMS2_k127_4763505_0 CHASE - - - 0.0 1262.0
CMS2_k127_4763505_1 response regulator K20977 - - 1.449e-206 646.0
CMS2_k127_4763505_2 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 396.0
CMS2_k127_4763505_3 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 295.0
CMS2_k127_4763505_4 RNA-DNA hybrid ribonuclease activity K02343,K03469 - 2.7.7.7,3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 289.0
CMS2_k127_4763505_5 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 280.0
CMS2_k127_4856508_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 1.441e-298 918.0
CMS2_k127_4856508_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 1.296e-279 865.0
CMS2_k127_4856508_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 9.905e-248 769.0
CMS2_k127_4856508_3 protein secretion K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 4.324e-206 652.0
CMS2_k127_4856508_4 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 307.0
CMS2_k127_4856508_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002158 275.0
CMS2_k127_4857708_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0 1025.0
CMS2_k127_4857708_1 Belongs to the GcvT family K06980 - - 7.857e-222 690.0
CMS2_k127_4857708_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 509.0
CMS2_k127_4857708_3 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 344.0
CMS2_k127_4857708_4 PFAM Positive regulator of sigma(E), RseC MucC K03803 - - 0.000000000000000000000000000000000000000000000000000001669 193.0
CMS2_k127_4864014_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.0 1129.0
CMS2_k127_4864014_1 PFAM Peptidase family M48 K06013 - 3.4.24.84 2.085e-264 816.0
CMS2_k127_4864014_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1.778e-213 664.0
CMS2_k127_4864014_3 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 342.0
CMS2_k127_4864014_4 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009777 317.0
CMS2_k127_4864014_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008168 264.0
CMS2_k127_4864014_6 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.0000000000000000000000000000000000000000000000000000000000000005178 220.0
CMS2_k127_4865200_0 Belongs to the UPF0061 (SELO) family K08997 - - 2.95e-305 937.0
CMS2_k127_4865200_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 5.801e-305 936.0
CMS2_k127_4865200_2 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000000000000000006112 116.0
CMS2_k127_4879060_0 peptidase K01414 - 3.4.24.70 0.0 1283.0
CMS2_k127_4879060_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0 1039.0
CMS2_k127_4879060_10 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001583 278.0
CMS2_k127_4879060_11 - K09004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001552 272.0
CMS2_k127_4879060_12 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003969 272.0
CMS2_k127_4879060_13 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008568 264.0
CMS2_k127_4879060_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001076 242.0
CMS2_k127_4879060_15 Secondary thiamine-phosphate synthase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000594 227.0
CMS2_k127_4879060_17 Putative ATP-dependant zinc protease - - - 0.00000000000000000000000000008425 123.0
CMS2_k127_4879060_18 Uncharacterized ArCR, COG1888 K09732 - - 0.00000000000000000000000006052 109.0
CMS2_k127_4879060_19 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000003431 79.0
CMS2_k127_4879060_2 Na+/Pi-cotransporter K03324 - - 6.97e-322 991.0
CMS2_k127_4879060_3 phosphate-selective porin O and P - - - 6.443e-257 795.0
CMS2_k127_4879060_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 535.0
CMS2_k127_4879060_5 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 362.0
CMS2_k127_4879060_6 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 345.0
CMS2_k127_4879060_7 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 340.0
CMS2_k127_4879060_8 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004849 339.0
CMS2_k127_4879060_9 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 295.0
CMS2_k127_4903608_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 9.091e-308 945.0
CMS2_k127_4903608_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 604.0
CMS2_k127_4903608_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 550.0
CMS2_k127_4903608_3 Belongs to the Orn Lys Arg decarboxylase class-II family K01581,K01586 - 4.1.1.17,4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 550.0
CMS2_k127_4903608_4 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 508.0
CMS2_k127_4903608_5 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 390.0
CMS2_k127_4903608_6 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 324.0
CMS2_k127_4903608_7 Protein of unknown function (DUF454) K09790 - - 0.000000000000000000000000000000000000000000000009791 174.0
CMS2_k127_4903608_8 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000239 95.0
CMS2_k127_4944591_0 AMP-binding enzyme - - - 1.219e-196 618.0
CMS2_k127_4944591_1 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000002647 219.0
CMS2_k127_4944591_2 Phosphopantetheine attachment site K02078 - - 0.00000000000000000000000000000000000000000006864 160.0
CMS2_k127_4961829_0 Tetratricopeptide repeat - - - 4.646e-304 940.0
CMS2_k127_4961829_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 9.64e-223 693.0
CMS2_k127_4961829_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 4.94e-197 616.0
CMS2_k127_4961829_3 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 386.0
CMS2_k127_4961829_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 368.0
CMS2_k127_4961829_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003422 295.0
CMS2_k127_5052313_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 2094.0
CMS2_k127_5052313_1 Belongs to the CarA family K01956 - 6.3.5.5 4.904e-242 749.0
CMS2_k127_5052313_2 Protein of unknown function (DUF455) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 505.0
CMS2_k127_5052313_3 Pfam Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 428.0
CMS2_k127_5052313_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 302.0
CMS2_k127_5075672_0 Secretion system protein K02454,K02652 - - 0.0 1096.0
CMS2_k127_5075672_2 type II secretion K02653 - - 5.744e-242 749.0
CMS2_k127_5075672_3 Type II and III secretion system protein K02453 - - 5.919e-217 677.0
CMS2_k127_5075672_4 Tetratricopeptide repeats - - - 1.258e-209 666.0
CMS2_k127_5075672_5 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 420.0
CMS2_k127_5080635_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1080.0
CMS2_k127_5084641_0 Binding-protein-dependent transport system inner membrane component K02050 - - 1.428e-206 643.0
CMS2_k127_5084641_1 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 591.0
CMS2_k127_5084641_2 Uncharacterised protein family (UPF0160) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 534.0
CMS2_k127_5084641_3 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 484.0
CMS2_k127_5084641_4 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 319.0
CMS2_k127_5084641_5 NikR C terminal nickel binding domain K07722 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 286.0
CMS2_k127_5084641_6 Thioredoxin K03671 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003127 253.0
CMS2_k127_5084641_7 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family - - - 0.000000000000000000000000000000000000000004493 156.0
CMS2_k127_509158_0 Domain of unknown function (DUF4055) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 332.0
CMS2_k127_509158_1 Head morphogenesis protein - - - 0.0000000000000008728 84.0
CMS2_k127_509957_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 1.751e-308 946.0
CMS2_k127_509957_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007557 527.0
CMS2_k127_509957_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 485.0
CMS2_k127_509957_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 482.0
CMS2_k127_509957_4 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005499 275.0
CMS2_k127_509957_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000001518 258.0
CMS2_k127_509957_6 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001326 241.0
CMS2_k127_509957_7 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.00000000000000000000000000005185 115.0
CMS2_k127_5114569_0 DNA photolyase K01669 - 4.1.99.3 3.854e-302 929.0
CMS2_k127_5114569_1 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 496.0
CMS2_k127_5114569_3 - - - - 0.000000000000000000000000000000000000000000000000000000001455 201.0
CMS2_k127_5114569_4 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000001327 191.0
CMS2_k127_5120804_0 von Willebrand factor (vWF) type A domain K07114 - - 0.0 1198.0
CMS2_k127_5120804_1 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 557.0
CMS2_k127_5120804_2 COG2931, RTX toxins and related Ca2 -binding proteins K12549 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 458.0
CMS2_k127_5120804_3 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 319.0
CMS2_k127_5120804_4 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 291.0
CMS2_k127_5120804_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001365 272.0
CMS2_k127_5144989_0 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 482.0
CMS2_k127_5144989_1 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 325.0
CMS2_k127_5144989_2 ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 293.0
CMS2_k127_5144989_3 transaminase activity K00375,K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000782 235.0
CMS2_k127_5144989_4 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0004874 46.0
CMS2_k127_5145465_0 acetamidase formamidase K01455 - 3.5.1.49 3.98e-245 759.0
CMS2_k127_5145465_1 Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates K01426 - 3.5.1.4 1.642e-223 693.0
CMS2_k127_5145465_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 377.0
CMS2_k127_5145465_11 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 359.0
CMS2_k127_5145465_12 ABC transporter ATP-binding protein K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 349.0
CMS2_k127_5145465_13 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 319.0
CMS2_k127_5145465_14 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 296.0
CMS2_k127_5145465_15 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000153 285.0
CMS2_k127_5145465_16 SEC-C Motif Domain Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000115 270.0
CMS2_k127_5145465_17 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002642 270.0
CMS2_k127_5145465_18 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006217 246.0
CMS2_k127_5145465_19 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.0000000000000000000000000000000000000000000000000000000000001068 215.0
CMS2_k127_5145465_2 Periplasmic binding protein domain K01999,K11959 - - 5.476e-223 696.0
CMS2_k127_5145465_20 Putative regulatory protein - - - 0.0000000000000000000000000000000000000002599 152.0
CMS2_k127_5145465_21 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.000000000000000000008725 91.0
CMS2_k127_5145465_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 598.0
CMS2_k127_5145465_4 Branched-chain amino acid transport system / permease component K01998,K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 561.0
CMS2_k127_5145465_5 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 486.0
CMS2_k127_5145465_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 463.0
CMS2_k127_5145465_7 ABC transporter ATP-binding K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 429.0
CMS2_k127_5145465_8 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 432.0
CMS2_k127_5145465_9 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 396.0
CMS2_k127_5157551_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.0 1514.0
CMS2_k127_5157551_1 Belongs to the BCCT transporter (TC 2.A.15) family K02168 - - 0.0 1203.0
CMS2_k127_5157551_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007751 333.0
CMS2_k127_5157551_11 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 315.0
CMS2_k127_5157551_12 Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008615 278.0
CMS2_k127_5157551_13 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002826 272.0
CMS2_k127_5157551_14 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004412 261.0
CMS2_k127_5157551_15 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001109 255.0
CMS2_k127_5157551_16 - - - - 0.000000000000000000000000000000000000000000000000000000001011 202.0
CMS2_k127_5157551_17 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000000000000000000000001931 145.0
CMS2_k127_5157551_18 ChrR Cupin-like domain - - - 0.0000000000008296 67.0
CMS2_k127_5157551_2 Heat shock 70 kDa protein K04043 - - 0.0 1182.0
CMS2_k127_5157551_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.0 1009.0
CMS2_k127_5157551_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 - 1.4.1.4 3.217e-229 714.0
CMS2_k127_5157551_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 5.07e-205 639.0
CMS2_k127_5157551_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 577.0
CMS2_k127_5157551_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0000988,GO:0000989,GO:0003674,GO:0003756,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010556,GO:0015035,GO:0015036,GO:0016020,GO:0016032,GO:0016043,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0016989,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031326,GO:0032991,GO:0034641,GO:0034645,GO:0042026,GO:0043167,GO:0043169,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051704,GO:0055114,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0140096,GO:0140110,GO:1901360,GO:1901576,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 473.0
CMS2_k127_5157551_9 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 404.0
CMS2_k127_5192063_0 - - - - 0.000000000000000000001009 102.0
CMS2_k127_5192063_2 repressor protein - - - 0.0000000000036 72.0
CMS2_k127_5192063_3 - - - - 0.00000000003845 66.0
CMS2_k127_5198886_0 ABC transporter - - - 0.0 1075.0
CMS2_k127_5198886_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.479e-277 854.0
CMS2_k127_5198886_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 303.0
CMS2_k127_5198886_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 282.0
CMS2_k127_5198886_4 periplasmic ligand-binding sensor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 280.0
CMS2_k127_5199899_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.457e-309 949.0
CMS2_k127_5199899_1 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 6.806e-221 687.0
CMS2_k127_5199899_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 564.0
CMS2_k127_5199899_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000572 181.0
CMS2_k127_5215595_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0 1070.0
CMS2_k127_5215595_1 LysR substrate binding domain K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 586.0
CMS2_k127_5215595_2 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 434.0
CMS2_k127_5215595_3 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 389.0
CMS2_k127_5215595_4 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 339.0
CMS2_k127_5215595_5 tryptophan synthase subunit beta - - - 0.000000000000000000000000000000000000000000000000000000003254 200.0
CMS2_k127_5226324_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0 1202.0
CMS2_k127_5226324_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000001495 224.0
CMS2_k127_5229444_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 1.486e-269 832.0
CMS2_k127_5229444_1 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 456.0
CMS2_k127_5229444_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 408.0
CMS2_k127_5232471_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1913.0
CMS2_k127_5232471_1 PFAM von Willebrand factor type A - - - 0.0 1532.0
CMS2_k127_5232471_10 Efflux transporter, RND family, MFP subunit - - - 1.118e-216 678.0
CMS2_k127_5232471_11 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 7.456e-215 668.0
CMS2_k127_5232471_12 Transcriptional regulator, LysR family K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009393 586.0
CMS2_k127_5232471_13 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 578.0
CMS2_k127_5232471_14 PFAM AAA domain (dynein-related subfamily) K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009156 555.0
CMS2_k127_5232471_15 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 549.0
CMS2_k127_5232471_16 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 532.0
CMS2_k127_5232471_17 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 521.0
CMS2_k127_5232471_18 belongs to the thioredoxin family K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 469.0
CMS2_k127_5232471_19 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 447.0
CMS2_k127_5232471_2 von Willebrand factor type A domain - - - 0.0 1478.0
CMS2_k127_5232471_20 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 416.0
CMS2_k127_5232471_21 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 378.0
CMS2_k127_5232471_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 355.0
CMS2_k127_5232471_23 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 286.0
CMS2_k127_5232471_25 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000006417 245.0
CMS2_k127_5232471_26 YcgL domain-containing protein K09902 - - 0.0000000000000000000000000000000000000004264 151.0
CMS2_k127_5232471_27 - - - - 0.0000000000000000000000000001083 115.0
CMS2_k127_5232471_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1280.0
CMS2_k127_5232471_4 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.0 1003.0
CMS2_k127_5232471_5 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 2.833e-311 953.0
CMS2_k127_5232471_6 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.108e-298 919.0
CMS2_k127_5232471_7 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K00974 - 2.7.7.72 2.109e-243 755.0
CMS2_k127_5232471_8 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.781e-240 746.0
CMS2_k127_5232471_9 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 3.102e-228 707.0
CMS2_k127_5239549_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1301.0
CMS2_k127_5239549_1 ATP-dependent helicase K03578 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 589.0
CMS2_k127_5239549_2 Protein of unknown function (DUF3087) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 311.0
CMS2_k127_5239549_3 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000001905 162.0
CMS2_k127_5250641_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1195.0
CMS2_k127_5250641_1 ABC transporter, ATP-binding protein - - - 0.0 1024.0
CMS2_k127_5250641_2 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 548.0
CMS2_k127_5250641_3 Carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 452.0
CMS2_k127_5250641_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 317.0
CMS2_k127_5274203_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 5.674e-309 949.0
CMS2_k127_5274203_1 Thioredoxin K03671,K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 551.0
CMS2_k127_5274203_2 Prokaryotic cytochrome b561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 341.0
CMS2_k127_5274203_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000003807 215.0
CMS2_k127_5319347_0 Ammonium Transporter Family K03320 - - 6.963e-289 898.0
CMS2_k127_5319347_1 HI0933-like protein K07007 - - 4.404e-240 745.0
CMS2_k127_5319347_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 9.331e-211 657.0
CMS2_k127_5319347_3 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002306 245.0
CMS2_k127_5338675_0 Bacterial periplasmic substrate-binding proteins - - - 5.468e-283 895.0
CMS2_k127_5338675_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000009768 263.0
CMS2_k127_5338675_2 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000000000002387 156.0
CMS2_k127_5338675_3 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001408 102.0
CMS2_k127_5338675_4 Cytochrome c - - - 0.0000000000003569 68.0
CMS2_k127_5340074_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1723.0
CMS2_k127_5340074_1 PFAM Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 2.013e-283 872.0
CMS2_k127_5340074_2 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 3.418e-248 768.0
CMS2_k127_5340074_3 UPF0126 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 405.0
CMS2_k127_5340074_4 growth of symbiont in host cell K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 405.0
CMS2_k127_5340074_5 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 320.0
CMS2_k127_5340074_6 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 323.0
CMS2_k127_5345998_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.42e-293 901.0
CMS2_k127_5345998_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 8.313e-272 838.0
CMS2_k127_5345998_2 HflC and HflK could encode or regulate a protease K04088 - - 8.54e-240 743.0
CMS2_k127_5345998_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 5.245e-231 717.0
CMS2_k127_5345998_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 594.0
CMS2_k127_5345998_5 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 534.0
CMS2_k127_5345998_6 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000000000006801 163.0
CMS2_k127_5345998_7 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.0000000000000000000000003374 106.0
CMS2_k127_5347746_0 Domain of unknown function (DUF3400) - - - 0.0 1064.0
CMS2_k127_5347746_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.081e-299 920.0
CMS2_k127_5347746_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 4.236e-248 767.0
CMS2_k127_5347746_3 histidyl-tRNA synthetase K01892 - 6.1.1.21 3.211e-211 657.0
CMS2_k127_5347746_4 Tetratricopeptide repeat-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 373.0
CMS2_k127_5352203_0 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0 1325.0
CMS2_k127_5352203_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1130.0
CMS2_k127_5352203_10 Domain of unknown function (DUF4381) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 311.0
CMS2_k127_5352203_11 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008073 285.0
CMS2_k127_5352203_12 FAD binding domain - - - 0.000000000000000000000001656 102.0
CMS2_k127_5352203_2 von Willebrand factor, type A K07114 - - 1.059e-320 994.0
CMS2_k127_5352203_3 Oxygen tolerance - - - 4.801e-307 947.0
CMS2_k127_5352203_4 Cysteine-rich domain K11473 - - 1.613e-263 812.0
CMS2_k127_5352203_5 PFAM ATPase associated with various cellular activities K03924 - - 1.023e-204 638.0
CMS2_k127_5352203_6 von Willebrand factor, type A K07114 - - 8.092e-194 607.0
CMS2_k127_5352203_7 Major Facilitator Superfamily K05939 - 2.3.1.40,6.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 608.0
CMS2_k127_5352203_8 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 589.0
CMS2_k127_5352203_9 - K09004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 364.0
CMS2_k127_536669_0 GAF domain K02584 - - 0.0 1041.0
CMS2_k127_536669_1 Rubredoxin K05297 - 1.18.1.1 5.853e-271 836.0
CMS2_k127_536669_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 7.471e-227 704.0
CMS2_k127_536669_3 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001076 230.0
CMS2_k127_5373112_0 phosphate-selective porin O and P - - - 6.544e-235 729.0
CMS2_k127_5373112_1 FMN_bind - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 356.0
CMS2_k127_5373112_2 PFAM PepSY-associated TM helix domain protein - - - 0.0000122 48.0
CMS2_k127_5375894_0 COG1943 Transposase and inactivated derivatives - - - 0.00000000000000000000000001412 113.0
CMS2_k127_5375894_1 COG1943 Transposase and inactivated derivatives - - - 0.00000000009461 62.0
CMS2_k127_5387461_0 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 339.0
CMS2_k127_5387461_1 beta-lactamase activity K07126,K13582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 312.0
CMS2_k127_5395983_0 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 6.352e-240 745.0
CMS2_k127_5395983_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 7.654e-202 629.0
CMS2_k127_5395983_2 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 411.0
CMS2_k127_5401257_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.27e-322 987.0
CMS2_k127_5401257_1 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 5.245e-256 795.0
CMS2_k127_5401257_10 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000009395 237.0
CMS2_k127_5401257_11 Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000000000000000000000000001068 192.0
CMS2_k127_5401257_2 C-type monoheme cytochrome, which is part of the SoxAX cytochrome complex involved in sulfur oxidation. The SoxAX complex catalyzes the formation of a heterodisulfide bond between the conserved cysteine residue on a sulfur carrier SoxYZ complex subunit SoxY and thiosulfate or other inorganic sulfur substrates. This leads to the intermediary formation of conspicuous sulfur globules inside of the cells K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 535.0
CMS2_k127_5401257_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 517.0
CMS2_k127_5401257_4 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 337.0
CMS2_k127_5401257_6 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008197 285.0
CMS2_k127_5401257_7 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002158 275.0
CMS2_k127_5401257_8 PFAM Mo-dependent nitrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004779 258.0
CMS2_k127_5401257_9 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000258 243.0
CMS2_k127_5412739_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1519.0
CMS2_k127_5412739_1 Permease for cytosine/purines, uracil, thiamine, allantoin - - - 1.306e-257 799.0
CMS2_k127_5412739_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 3.024e-214 666.0
CMS2_k127_5412739_3 Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates K01455 GO:0003674,GO:0003824,GO:0004040,GO:0016787,GO:0016810,GO:0016811 3.5.1.49 6.226e-210 653.0
CMS2_k127_5412739_4 Diguanylate cyclase K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 382.0
CMS2_k127_5412739_5 diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000004173 199.0
CMS2_k127_5420108_0 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000002403 178.0
CMS2_k127_5437092_0 Diguanylate cyclase - - - 0.0 1424.0
CMS2_k127_5437092_1 Acetyltransferase (GNAT) domain - - - 0.0 1097.0
CMS2_k127_5437092_10 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 300.0
CMS2_k127_5437092_11 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 282.0
CMS2_k127_5437092_12 Protein of unknown function (DUF2789) - - - 0.00000000000000000000000035 105.0
CMS2_k127_5437092_2 diguanylate cyclase - - - 2.589e-310 968.0
CMS2_k127_5437092_3 Belongs to the peptidase M16 family K07263 - - 1.343e-270 837.0
CMS2_k127_5437092_4 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 - 3.6.4.13 1.588e-265 821.0
CMS2_k127_5437092_5 Peptidase M16 K07263 - - 1.381e-250 777.0
CMS2_k127_5437092_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 1.485e-203 638.0
CMS2_k127_5437092_7 S1 domain K00243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 534.0
CMS2_k127_5437092_8 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 456.0
CMS2_k127_5437092_9 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 379.0
CMS2_k127_5444793_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 441.0
CMS2_k127_5444793_1 Deoxynucleoside kinase - - - 0.0000000000000000000004595 102.0
CMS2_k127_5458816_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1294.0
CMS2_k127_5458816_1 peptidase - - - 1.316e-224 701.0
CMS2_k127_5458816_2 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 7.439e-208 646.0
CMS2_k127_5458816_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 2.439e-204 640.0
CMS2_k127_5458816_4 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 452.0
CMS2_k127_5458816_5 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 361.0
CMS2_k127_5458816_6 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 329.0
CMS2_k127_5458816_7 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000007967 136.0
CMS2_k127_5462974_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 482.0
CMS2_k127_5462974_1 PFAM GDSL-like Lipase Acylhydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000002497 222.0
CMS2_k127_5463018_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 4.176e-258 799.0
CMS2_k127_5463018_1 Domain of unknown function (DUF1949) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008794 353.0
CMS2_k127_5463018_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000001069 71.0
CMS2_k127_5465133_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 493.0
CMS2_k127_5465133_1 cell redox homeostasis K03671 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000014 268.0
CMS2_k127_5465133_2 Carbon-nitrogen hydrolase K13566 - 3.5.1.3 0.00000000001198 64.0
CMS2_k127_5466636_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1100.0
CMS2_k127_5466636_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 1.147e-196 614.0
CMS2_k127_5469738_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1187.0
CMS2_k127_5469738_1 Involved in the TonB-independent uptake of proteins K03641 - - 1.362e-257 798.0
CMS2_k127_5469738_10 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 415.0
CMS2_k127_5469738_11 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 400.0
CMS2_k127_5469738_12 MotA/TolQ/ExbB proton channel family K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 387.0
CMS2_k127_5469738_13 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 386.0
CMS2_k127_5469738_14 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006238 352.0
CMS2_k127_5469738_15 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 348.0
CMS2_k127_5469738_16 YaeQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 343.0
CMS2_k127_5469738_17 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 331.0
CMS2_k127_5469738_18 Protein of unknown function (DUF1456) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 308.0
CMS2_k127_5469738_19 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008662 321.0
CMS2_k127_5469738_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 3.832e-217 676.0
CMS2_k127_5469738_20 Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004452 277.0
CMS2_k127_5469738_21 queuosine biosynthesis protein QueD K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001823 256.0
CMS2_k127_5469738_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 6.834e-210 653.0
CMS2_k127_5469738_4 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 531.0
CMS2_k127_5469738_5 TonB C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 517.0
CMS2_k127_5469738_6 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 475.0
CMS2_k127_5469738_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 464.0
CMS2_k127_5469738_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 455.0
CMS2_k127_5469738_9 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009615 439.0
CMS2_k127_5481683_0 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 2.943e-194 612.0
CMS2_k127_5481683_2 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000004457 155.0
CMS2_k127_5481683_3 Type II secretion system (T2SS), protein M K02462 - - 0.0000000000000000000000000007527 118.0
CMS2_k127_5483558_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1795.0
CMS2_k127_5483558_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0 1185.0
CMS2_k127_5483558_10 NUDIX domain K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 352.0
CMS2_k127_5483558_11 Low-potential electron donor to a number of redox enzymes K03839,K03840 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 349.0
CMS2_k127_5483558_12 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000005946 240.0
CMS2_k127_5483558_13 - - - - 0.000000000000000000000000001016 113.0
CMS2_k127_5483558_2 PFAM CheW domain protein - - - 0.0 1178.0
CMS2_k127_5483558_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 - 6.3.1.5,6.3.5.1 3.786e-278 857.0
CMS2_k127_5483558_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 1.665e-221 688.0
CMS2_k127_5483558_5 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 524.0
CMS2_k127_5483558_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 515.0
CMS2_k127_5483558_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 454.0
CMS2_k127_5483558_8 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 409.0
CMS2_k127_5483558_9 N-acetylmuramoyl-L-alanine amidase K03806 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 364.0
CMS2_k127_5494167_0 Type II IV secretion system protein K02454,K02652 - - 1.101e-261 809.0
CMS2_k127_5494167_1 TIGRFAM general secretion pathway protein F K02455 - - 3.867e-235 731.0
CMS2_k127_5494167_2 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 362.0
CMS2_k127_5494167_3 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003656 275.0
CMS2_k127_5494167_4 cell adhesion K02650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000391 256.0
CMS2_k127_5494167_5 Prokaryotic N-terminal methylation motif K02456,K02458,K02655,K12285 - - 0.000000000000000000000000000000000000000000000000000000006302 200.0
CMS2_k127_5499917_0 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 443.0
CMS2_k127_5499917_1 Alkyl hydroperoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 353.0
CMS2_k127_5499917_2 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006677 353.0
CMS2_k127_5499917_3 Sensory box GGDEF EAL domain-containing protein - - - 0.0000000000000000000000000000000002213 143.0
CMS2_k127_5504838_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0 1213.0
CMS2_k127_5504838_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1071.0
CMS2_k127_5504838_2 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 1.007e-255 792.0
CMS2_k127_5504838_3 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 421.0
CMS2_k127_5504838_4 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 420.0
CMS2_k127_5504838_5 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 408.0
CMS2_k127_5504838_6 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000000000000000000002543 235.0
CMS2_k127_5505279_0 protein involved in response to NO K07234 - - 3.78e-197 621.0
CMS2_k127_5505279_1 glutamate--cysteine ligase K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002606 271.0
CMS2_k127_5532737_0 ABC-type Zn2 transport system, periplasmic component surface adhesin K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 503.0
CMS2_k127_5532737_1 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 289.0
CMS2_k127_5532737_2 - - - - 0.0000000000000000000000000000000000000000001259 160.0
CMS2_k127_55421_0 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 342.0
CMS2_k127_55421_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 315.0
CMS2_k127_55421_2 Domain of unknown function (DUF3817) - - - 0.0000000000000000000000000000000000000000116 154.0
CMS2_k127_55421_3 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000008057 134.0
CMS2_k127_5548286_0 lysozyme K01185 - 3.2.1.17 0.000000000000000000000000000000001466 134.0
CMS2_k127_5548286_1 - - - - 0.00000000001369 66.0
CMS2_k127_5564517_0 Acetyltransferase (GNAT) family - - - 0.000000000000002692 77.0
CMS2_k127_5564517_1 Molydopterin dinucleotide binding domain - - - 0.0000000007293 61.0
CMS2_k127_5606381_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1247.0
CMS2_k127_5606381_1 chemotaxis, protein K03406 - - 1.069e-319 984.0
CMS2_k127_5606381_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526,K03676 - 1.17.4.1 1.183e-237 736.0
CMS2_k127_5606381_3 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 422.0
CMS2_k127_5606381_4 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 420.0
CMS2_k127_5606381_5 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 372.0
CMS2_k127_5606381_7 OmpA family K02557 - - 0.00000000000000000000008098 98.0
CMS2_k127_5647967_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1683.0
CMS2_k127_5647967_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 1.423e-233 724.0
CMS2_k127_5647967_2 Tetrahydrodipicolinate N-succinyltransferase middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 577.0
CMS2_k127_5647967_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 493.0
CMS2_k127_5647967_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 469.0
CMS2_k127_5647967_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004135 244.0
CMS2_k127_5647967_6 Belongs to the ArsC family - - - 0.000000000000000000000000000000000000000000000000000001567 192.0
CMS2_k127_5647967_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000001197 186.0
CMS2_k127_5703745_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1297.0
CMS2_k127_5703745_1 Putative diguanylate phosphodiesterase - - - 6.833e-246 765.0
CMS2_k127_5703745_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 8.843e-245 758.0
CMS2_k127_5703745_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 2.255e-216 675.0
CMS2_k127_5703745_4 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 529.0
CMS2_k127_5703745_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 291.0
CMS2_k127_5706230_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 585.0
CMS2_k127_5706230_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 539.0
CMS2_k127_5706230_10 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001611 246.0
CMS2_k127_5706230_12 2 iron, 2 sulfur cluster binding K07390 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.000000000000000000000000000000004074 129.0
CMS2_k127_5706230_2 PFAM sodium calcium exchanger K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 531.0
CMS2_k127_5706230_3 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009408 476.0
CMS2_k127_5706230_4 ABC transporter permease K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 474.0
CMS2_k127_5706230_5 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 369.0
CMS2_k127_5706230_6 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 363.0
CMS2_k127_5706230_7 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 349.0
CMS2_k127_5706230_8 toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 350.0
CMS2_k127_5706230_9 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004668 277.0
CMS2_k127_5710055_0 malic enzyme K00027 - 1.1.1.38 4.945e-242 751.0
CMS2_k127_5710055_1 HDOD domain - - - 3.135e-222 692.0
CMS2_k127_5710055_2 Iron-regulated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 426.0
CMS2_k127_5732871_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1465.0
CMS2_k127_5732871_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 291.0
CMS2_k127_57775_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 5.134e-271 837.0
CMS2_k127_57775_1 protein conserved in bacteria K09906 GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0017185,GO:0018126,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0055114,GO:0071704,GO:0072580,GO:1901260,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007879 263.0
CMS2_k127_5789607_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 5.996e-298 922.0
CMS2_k127_5789607_1 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 516.0
CMS2_k127_5789607_2 protein affecting phage T7 exclusion by the F plasmid K07113 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006188 269.0
CMS2_k127_5789607_3 aromatic hydrocarbon degradation K06076 - - 0.000000000008746 65.0
CMS2_k127_5942672_0 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 298.0
CMS2_k127_5942672_1 - - - - 0.0000000000000000000000000000000000000000000000000008836 185.0
CMS2_k127_5942672_2 - - - - 0.0007585 46.0
CMS2_k127_5965466_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 8.942e-240 743.0
CMS2_k127_5978987_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009711 344.0
CMS2_k127_5978987_1 O-Antigen ligase K13009 - - 0.000000000000000000000000000000000000000000000000000000000006551 228.0
CMS2_k127_5978987_2 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000001878 103.0
CMS2_k127_6034795_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0 1072.0
CMS2_k127_6034795_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 556.0
CMS2_k127_6034795_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007932 238.0
CMS2_k127_6047409_0 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 9.354e-227 707.0
CMS2_k127_6047409_1 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 292.0
CMS2_k127_6047409_2 - - - - 0.000000000000000005993 87.0
CMS2_k127_60607_0 Belongs to the peptidase S16 family K04770 - - 0.0 1478.0
CMS2_k127_60607_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0 1448.0
CMS2_k127_60607_2 Ammonium Transporter Family K03320 - - 2.946e-259 800.0
CMS2_k127_60607_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 3.514e-211 659.0
CMS2_k127_60607_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 495.0
CMS2_k127_60607_5 Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC K02016,K06858 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0008144,GO:0008150,GO:0015889,GO:0015893,GO:0019842,GO:0030288,GO:0030313,GO:0031419,GO:0031975,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000007508 187.0
CMS2_k127_60607_6 protein conserved in bacteria K09928 - - 0.000000000000000000000000000000000000000000000003328 178.0
CMS2_k127_60607_7 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000000000001982 143.0
CMS2_k127_60607_8 Belongs to the UPF0434 family K09791 - - 0.00000000000000000000000000000001423 126.0
CMS2_k127_60607_9 - - - - 0.000000000000000000000000002816 111.0
CMS2_k127_6078287_0 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243,K18284 - 3.2.2.30,3.2.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 440.0
CMS2_k127_6078287_1 Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) K07173 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0007154,GO:0007267,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009116,GO:0009119,GO:0009372,GO:0009987,GO:0010699,GO:0016053,GO:0016829,GO:0016846,GO:0017144,GO:0019284,GO:0019752,GO:0023052,GO:0033353,GO:0034641,GO:0042278,GO:0043094,GO:0043102,GO:0043436,GO:0043768,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046128,GO:0046394,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0051704,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657 4.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 340.0
CMS2_k127_6078287_2 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 335.0
CMS2_k127_6078287_3 RDD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 289.0
CMS2_k127_61282_0 The M ring may be actively involved in energy transduction K02409 - - 0.0 1027.0
CMS2_k127_61282_1 PFAM response regulator receiver K10943 - - 5.466e-276 852.0
CMS2_k127_61282_10 flagellar export protein FliJ K02413 - - 0.0000000000000000000000000000000000000000000000000000000000000007507 221.0
CMS2_k127_61282_11 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000000000000000000000000000000000000008695 190.0
CMS2_k127_61282_2 TIGRFAM ATPase, FliI YscN family K02412 - 3.6.3.14 1.929e-273 843.0
CMS2_k127_61282_3 PAS domain K10942 - 2.7.13.3 8.989e-227 704.0
CMS2_k127_61282_4 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 1.915e-207 646.0
CMS2_k127_61282_5 Sigma-54 interaction domain K10941 - - 2.089e-202 634.0
CMS2_k127_61282_6 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 528.0
CMS2_k127_61282_7 Flagellar hook-length control protein K02414 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005572 528.0
CMS2_k127_61282_8 Flagellar assembly protein FliH K02411 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 425.0
CMS2_k127_61282_9 flagellar protein FliS K02422 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005405 267.0
CMS2_k127_6133237_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1177.0
CMS2_k127_6133237_1 Diguanylate cyclase - - - 1.507e-234 742.0
CMS2_k127_6133237_10 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 380.0
CMS2_k127_6133237_11 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 342.0
CMS2_k127_6133237_12 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 312.0
CMS2_k127_6133237_13 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004808 301.0
CMS2_k127_6133237_14 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000002739 224.0
CMS2_k127_6133237_2 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 4.9e-234 726.0
CMS2_k127_6133237_3 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 1.736e-226 701.0
CMS2_k127_6133237_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 1.155e-224 698.0
CMS2_k127_6133237_5 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division K08306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 594.0
CMS2_k127_6133237_6 DNA RNA non-specific endonuclease K01173 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 476.0
CMS2_k127_6133237_7 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 472.0
CMS2_k127_6133237_8 Glucose-regulated metallo-peptidase M90 K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 452.0
CMS2_k127_6133237_9 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 459.0
CMS2_k127_6142752_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 3.52e-248 767.0
CMS2_k127_6142752_1 FolM Alternative dihydrofolate reductase 1 K13938 - 1.5.1.3,1.5.1.50 0.00000000000000000005573 89.0
CMS2_k127_6155356_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1573.0
CMS2_k127_6155356_1 Domain of unknown function (DUF389) - - - 0.0 1079.0
CMS2_k127_6155356_10 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 537.0
CMS2_k127_6155356_11 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009522 507.0
CMS2_k127_6155356_12 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 486.0
CMS2_k127_6155356_13 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 482.0
CMS2_k127_6155356_14 Protein of unknown function (DUF3581) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 470.0
CMS2_k127_6155356_15 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 414.0
CMS2_k127_6155356_16 pathogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 359.0
CMS2_k127_6155356_17 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 318.0
CMS2_k127_6155356_18 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004253 274.0
CMS2_k127_6155356_19 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001691 266.0
CMS2_k127_6155356_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0 1029.0
CMS2_k127_6155356_20 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006793 256.0
CMS2_k127_6155356_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006607 249.0
CMS2_k127_6155356_22 Belongs to the HSP15 family K04762 - - 0.000000000000000000000000000000000000000000000000000000000000000000003324 235.0
CMS2_k127_6155356_23 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000887 218.0
CMS2_k127_6155356_24 Alcohol dehydrogenase GroES-like domain K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000002524 215.0
CMS2_k127_6155356_26 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000009583 196.0
CMS2_k127_6155356_27 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000000003518 93.0
CMS2_k127_6155356_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 1.088e-288 889.0
CMS2_k127_6155356_4 Belongs to the peptidase S16 family - - - 2.339e-281 886.0
CMS2_k127_6155356_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 3.333e-231 718.0
CMS2_k127_6155356_6 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 2.621e-215 670.0
CMS2_k127_6155356_7 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 1.383e-211 657.0
CMS2_k127_6155356_8 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 599.0
CMS2_k127_6155356_9 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 554.0
CMS2_k127_6156278_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 2.387e-219 683.0
CMS2_k127_6156278_1 Flagellar hook-length control protein FliK - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 578.0
CMS2_k127_6156278_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006479,GO:0006807,GO:0006935,GO:0008022,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0008983,GO:0009605,GO:0009987,GO:0010340,GO:0016020,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0032991,GO:0036211,GO:0040011,GO:0042221,GO:0042330,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051998,GO:0071704,GO:0071944,GO:0098561,GO:0140096,GO:1901564 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 535.0
CMS2_k127_6156278_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000953 101.0
CMS2_k127_6171120_0 MotA/TolQ/ExbB proton channel family K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 561.0
CMS2_k127_6171120_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 540.0
CMS2_k127_6171120_2 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006324 442.0
CMS2_k127_6171120_3 Flagellar hook-length control protein K02414 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 286.0
CMS2_k127_6182797_0 RIO1 family K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 532.0
CMS2_k127_6182797_1 Serine/threonine phosphatases, family 2C, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 445.0
CMS2_k127_6182797_10 RIO1 family K07178 - 2.7.11.1 0.00009277 45.0
CMS2_k127_6182797_2 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 415.0
CMS2_k127_6182797_3 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 381.0
CMS2_k127_6182797_4 Methylamine dehydrogenase, L chain K15228 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.4.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002185 280.0
CMS2_k127_6182797_5 AhpC/TSA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008773 276.0
CMS2_k127_6182797_6 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000003958 158.0
CMS2_k127_6182797_7 Cytochrome c - - - 0.000000000000000000000000000000000000000001436 160.0
CMS2_k127_6182797_8 Methylamine utilisation protein MauE - - - 0.00000000000000000000000000009144 122.0
CMS2_k127_6182797_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000002958 116.0
CMS2_k127_6207675_0 GHMP kinases N terminal domain K01597 - 4.1.1.33 6.474e-194 608.0
CMS2_k127_6207675_1 Stringent starvation protein A K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 409.0
CMS2_k127_6207675_2 stringent starvation protein b K03600 GO:0000502,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0009376,GO:0009893,GO:0009894,GO:0009896,GO:0010604,GO:0019222,GO:0019899,GO:0031597,GO:0032781,GO:0032991,GO:0042176,GO:0042802,GO:0042803,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045732,GO:0046983,GO:0048518,GO:0050789,GO:0050790,GO:0051117,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:1901363,GO:1902494,GO:1904949,GO:1905368,GO:1905369,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 284.0
CMS2_k127_6207675_3 class II (D, K and N) K04568 - - 0.000000000007704 64.0
CMS2_k127_6217324_0 Putative diguanylate phosphodiesterase - - - 0.0 1480.0
CMS2_k127_6217324_1 LppC putative lipoprotein K07121 - - 2.665e-279 865.0
CMS2_k127_6217324_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 531.0
CMS2_k127_6217324_3 Specifically methylates the guanosine in position 1516 of 16S rRNA K15984 - 2.1.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 412.0
CMS2_k127_6217324_4 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000000000000000000000000000000000000004464 229.0
CMS2_k127_6240434_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.388e-296 910.0
CMS2_k127_6240434_1 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 393.0
CMS2_k127_6240434_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007379 271.0
CMS2_k127_6240434_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006335 265.0
CMS2_k127_6240434_4 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006762 241.0
CMS2_k127_6269971_0 COG2801 Transposase and inactivated derivatives K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006622 332.0
CMS2_k127_6269971_1 COG2801 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009302 258.0
CMS2_k127_6269971_2 Transposase K07483 - - 0.000000000000000000000000000000000000003906 147.0
CMS2_k127_6271841_0 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0 1132.0
CMS2_k127_6271841_1 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 412.0
CMS2_k127_6271841_2 Protein of unknown function (DUF3010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009815 302.0
CMS2_k127_6275435_0 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 604.0
CMS2_k127_6275435_1 MltA-interacting protein MipA K07274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 533.0
CMS2_k127_6275435_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007639 302.0
CMS2_k127_6275435_3 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001928 265.0
CMS2_k127_6279119_0 Sodium Bile acid symporter family K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 495.0
CMS2_k127_6279119_1 Belongs to the UPF0246 family K09861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 488.0
CMS2_k127_6279119_2 WLM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009177 317.0
CMS2_k127_6279119_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000000000000000000000000001287 177.0
CMS2_k127_6305215_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 3.988e-279 860.0
CMS2_k127_6305215_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 2.357e-220 685.0
CMS2_k127_6315945_0 Phage P22-like portal protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 436.0
CMS2_k127_6315945_1 Phage terminase, large subunit K06909 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 299.0
CMS2_k127_6320588_0 Type II and III secretion system protein K02453 - - 0.0 1145.0
CMS2_k127_6320588_1 - - - - 1.99e-226 722.0
CMS2_k127_6320588_2 protein transport across the cell outer membrane K02452 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 444.0
CMS2_k127_6320588_3 Uncharacterized protein domain (DUF2202) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 299.0
CMS2_k127_6320588_4 Uncharacterized protein domain (DUF2202) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 285.0
CMS2_k127_6347265_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 2.263e-266 822.0
CMS2_k127_6347265_1 Belongs to the UPF0149 family K09895 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 391.0
CMS2_k127_6347265_2 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 296.0
CMS2_k127_6347265_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000000000000000000006915 162.0
CMS2_k127_6347265_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000008318 126.0
CMS2_k127_6369717_0 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 565.0
CMS2_k127_6369717_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 314.0
CMS2_k127_6369717_2 thiamine biosynthesis protein ThiS K03154 - - 0.00000000000000000001436 92.0
CMS2_k127_6372557_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1194.0
CMS2_k127_6372557_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 4.17e-295 909.0
CMS2_k127_6372557_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.000000000000000000000000000000001006 130.0
CMS2_k127_6382627_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.0 1467.0
CMS2_k127_6382627_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 7.534e-300 921.0
CMS2_k127_6382627_10 Thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006019 229.0
CMS2_k127_6382627_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 1.538e-294 907.0
CMS2_k127_6382627_3 TIGRFAM lytic murein transglycosylase K08305 - - 6.518e-244 756.0
CMS2_k127_6382627_4 Patatin-like phospholipase K07001 - - 1.568e-233 728.0
CMS2_k127_6382627_5 Predicted permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 434.0
CMS2_k127_6382627_6 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 419.0
CMS2_k127_6382627_7 paraquat-inducible protein A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 336.0
CMS2_k127_6382627_8 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 330.0
CMS2_k127_6382627_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003613 269.0
CMS2_k127_6401491_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 596.0
CMS2_k127_6401491_1 Bacterial flagellin C-terminal helical region K02406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 412.0
CMS2_k127_6401491_3 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001093 254.0
CMS2_k127_6401491_4 Ammonium Transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002643 250.0
CMS2_k127_644740_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1591.0
CMS2_k127_644740_1 Outer membrane efflux protein - - - 9.439e-202 637.0
CMS2_k127_644740_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 530.0
CMS2_k127_644740_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000003408 194.0
CMS2_k127_6451315_0 P22 coat protein - gene protein 5 - - - 0.0000000000000000000000000000000000000000000001303 184.0
CMS2_k127_6451315_1 Phage stabilisation protein - - - 0.0000000000000000000000000000000000000000007994 174.0
CMS2_k127_6451315_2 - - - - 0.000000000000002366 86.0
CMS2_k127_6451315_3 DNA/protein translocase of phage P22 injectosome - - - 0.0000000000003065 81.0
CMS2_k127_6451315_4 Packaged DNA stabilization protein gp4 - - - 0.0000007086 59.0
CMS2_k127_6452598_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1191.0
CMS2_k127_6452598_1 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1113.0
CMS2_k127_6452598_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0 1021.0
CMS2_k127_6452598_3 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 494.0
CMS2_k127_6452598_4 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 417.0
CMS2_k127_6452598_5 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000000000000004013 184.0
CMS2_k127_6452598_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000002326 172.0
CMS2_k127_6481091_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 6.3e-322 990.0
CMS2_k127_6481091_1 Molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 475.0
CMS2_k127_6481091_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 456.0
CMS2_k127_6481091_3 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 430.0
CMS2_k127_6498998_0 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 441.0
CMS2_k127_6498998_1 Uncharacterised protein family (UPF0014) K02069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 431.0
CMS2_k127_6498998_2 Spermidine putrescine-binding periplasmic protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 309.0
CMS2_k127_6498998_3 abc transporter atp-binding protein K02068 GO:0005575,GO:0005623,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0016020,GO:0019725,GO:0030003,GO:0042592,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 289.0
CMS2_k127_6498998_4 (GGDEF) domain K20966 GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0023052,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007 3.1.4.52 0.00000000000000000000000000000000000000000000000000000005426 212.0
CMS2_k127_6505892_0 Hydroxymethylglutaryl-coenzyme A reductase K00021 - 1.1.1.34 8.731e-223 693.0
CMS2_k127_6505892_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 567.0
CMS2_k127_6505892_2 Peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000005306 172.0
CMS2_k127_6523446_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.328e-319 980.0
CMS2_k127_6523446_1 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 1.008e-196 614.0
CMS2_k127_6523446_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 407.0
CMS2_k127_6533709_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1680.0
CMS2_k127_6533709_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1012.0
CMS2_k127_6533709_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 1.818e-276 852.0
CMS2_k127_6533709_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 4.441e-223 694.0
CMS2_k127_6533709_4 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 3.907e-215 670.0
CMS2_k127_6533709_5 Prephenate dehydrogenase K00210,K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 525.0
CMS2_k127_6533709_6 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 410.0
CMS2_k127_6533709_7 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 394.0
CMS2_k127_6533709_8 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 313.0
CMS2_k127_6538277_0 Domain of unknown function (DUF3400) - - - 0.0 1531.0
CMS2_k127_6538277_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 441.0
CMS2_k127_6538277_2 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000003134 179.0
CMS2_k127_6538277_3 cytochrome - - - 0.0000000000000000000000000000000000000000000000005239 176.0
CMS2_k127_6542127_0 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 577.0
CMS2_k127_6542127_1 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000937 451.0
CMS2_k127_6542127_2 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 448.0
CMS2_k127_6542127_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 377.0
CMS2_k127_6542127_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009805 249.0
CMS2_k127_6542127_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000004707 243.0
CMS2_k127_6542127_7 Belongs to the PsiE family K13256 - - 0.0000000000000000000000000000000000000000000000591 174.0
CMS2_k127_6570319_0 Protein of unknown function (DUF3379) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 441.0
CMS2_k127_6570319_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 400.0
CMS2_k127_6570319_2 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 322.0
CMS2_k127_6577794_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 314.0
CMS2_k127_6577794_1 Transposase IS116 IS110 IS902 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009382 256.0
CMS2_k127_6577794_2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.000000000003484 67.0
CMS2_k127_6577794_3 Transposase K07486 - - 0.000000009175 56.0
CMS2_k127_6583945_0 Phage Terminase - - - 7.036e-248 775.0
CMS2_k127_6583945_1 PFAM phage major capsid protein, HK97 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 470.0
CMS2_k127_6583945_10 - - - - 0.000000000000000009947 88.0
CMS2_k127_6583945_11 - - - - 0.0000000000000002661 83.0
CMS2_k127_6583945_12 - - - - 0.00000000000001491 79.0
CMS2_k127_6583945_13 Bacteriophage HK97-gp10, putative tail-component - - - 0.000000000001177 74.0
CMS2_k127_6583945_14 Phage head-tail adaptor - - - 0.000000000005692 70.0
CMS2_k127_6583945_15 Protein of unknown function (DUF3168) - - - 0.000000004898 63.0
CMS2_k127_6583945_2 TIGRFAM phage portal protein, HK97 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 415.0
CMS2_k127_6583945_3 Clp protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000001003 245.0
CMS2_k127_6583945_4 nuclear chromosome segregation - - - 0.00000000000000000000000000000000000000000000000000002977 209.0
CMS2_k127_6583945_5 HNH nucleases K07451 - - 0.000000000000000000000000000000000000001572 149.0
CMS2_k127_6583945_6 Phage gp6-like head-tail connector protein - - - 0.000000000000000000000000000000000000006176 152.0
CMS2_k127_6583945_7 - - - - 0.00000000000000000000000000000000007616 141.0
CMS2_k127_6583945_8 Phage terminase, small subunit - - - 0.0000000000000000000000000000000221 131.0
CMS2_k127_6594579_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 524.0
CMS2_k127_6594579_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 325.0
CMS2_k127_6594579_2 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004624 249.0
CMS2_k127_6598812_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 364.0
CMS2_k127_6598812_1 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 315.0
CMS2_k127_6598812_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000000000000000000000000004273 220.0
CMS2_k127_6598812_3 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000284 152.0
CMS2_k127_6634369_0 Belongs to the GPI family K01810 - 5.3.1.9 0.0 1000.0
CMS2_k127_6634369_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 549.0
CMS2_k127_6653847_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 505.0
CMS2_k127_6653847_1 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002374 269.0
CMS2_k127_668915_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 0.0 1415.0
CMS2_k127_668915_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 501.0
CMS2_k127_668915_2 heat shock protein binding K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000927 482.0
CMS2_k127_668915_3 PhnA Zinc-Ribbon K06193 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 356.0
CMS2_k127_668915_4 Protein required for attachment to host cells - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002199 269.0
CMS2_k127_668915_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000000000000000000002827 220.0
CMS2_k127_6697920_0 haemagglutination activity domain - - - 8.642e-312 1048.0
CMS2_k127_670460_0 Anthranilate synthase component I K01657,K01665 - 2.6.1.85,4.1.3.27 1.806e-279 862.0
CMS2_k127_670460_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.299e-254 786.0
CMS2_k127_670460_10 haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 394.0
CMS2_k127_670460_11 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 370.0
CMS2_k127_670460_12 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 339.0
CMS2_k127_670460_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000000001816 144.0
CMS2_k127_670460_14 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000000000000002011 123.0
CMS2_k127_670460_15 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000009062 111.0
CMS2_k127_670460_16 Hydrolase, TatD family K03424 - - 0.00000000000000002212 81.0
CMS2_k127_670460_2 TIGRFAM DNA polymerase III, delta K02341 - 2.7.7.7 6.036e-223 693.0
CMS2_k127_670460_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 2.812e-210 655.0
CMS2_k127_670460_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 1.984e-203 634.0
CMS2_k127_670460_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 1.846e-195 612.0
CMS2_k127_670460_6 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 571.0
CMS2_k127_670460_7 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 541.0
CMS2_k127_670460_8 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 459.0
CMS2_k127_670460_9 Maf-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008449 399.0
CMS2_k127_6750722_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 7.46e-320 1013.0
CMS2_k127_6750722_1 efflux transmembrane transporter activity K12340,K12538 - - 7.714e-221 692.0
CMS2_k127_6750722_2 Acetyltransferase (GNAT) domain - - - 2.251e-200 639.0
CMS2_k127_6750722_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 509.0
CMS2_k127_6750722_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000001526 179.0
CMS2_k127_6758807_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 0.0 1240.0
CMS2_k127_6758807_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006528 510.0
CMS2_k127_6758807_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 384.0
CMS2_k127_6758807_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 326.0
CMS2_k127_6758807_4 - - - - 0.0000000000000000000004222 96.0
CMS2_k127_6763520_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 7.473e-297 913.0
CMS2_k127_6763520_1 Metallo-beta-lactamase superfamily - - - 5.03e-199 621.0
CMS2_k127_6763520_2 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 518.0
CMS2_k127_6763520_3 Cobalt uptake substrate-specific transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 357.0
CMS2_k127_6763520_4 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 308.0
CMS2_k127_6763520_5 membrane protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000543 255.0
CMS2_k127_6763520_6 Biopolymer transport K03561 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000004389 164.0
CMS2_k127_6768280_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 574.0
CMS2_k127_6768280_1 mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 482.0
CMS2_k127_6768280_2 membrane transporter protein K07090,K11312 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 448.0
CMS2_k127_6768280_3 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 296.0
CMS2_k127_6768280_4 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000005012 137.0
CMS2_k127_6787982_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1449.0
CMS2_k127_6787982_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 8.641e-263 811.0
CMS2_k127_6787982_10 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 391.0
CMS2_k127_6787982_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 361.0
CMS2_k127_6787982_12 YGGT family K02221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 354.0
CMS2_k127_6787982_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005405 267.0
CMS2_k127_6787982_14 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008437 265.0
CMS2_k127_6787982_15 coenzyme F420 binding K07226 - - 0.000000000000000000000000000000000000000000000000000000000000000001446 231.0
CMS2_k127_6787982_16 FeoC like transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000621 169.0
CMS2_k127_6787982_19 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000002334 81.0
CMS2_k127_6787982_2 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.189e-250 774.0
CMS2_k127_6787982_3 Large extracellular alpha-helical protein - - - 1.366e-246 781.0
CMS2_k127_6787982_4 - - - - 8.638e-196 611.0
CMS2_k127_6787982_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 510.0
CMS2_k127_6787982_6 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 508.0
CMS2_k127_6787982_8 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 422.0
CMS2_k127_6787982_9 Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 396.0
CMS2_k127_6791156_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.321e-247 765.0
CMS2_k127_6791156_1 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 382.0
CMS2_k127_6791156_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 327.0
CMS2_k127_6798324_0 Glycosyl transferase family group 2 - - - 0.0 1666.0
CMS2_k127_6798324_1 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000001769 175.0
CMS2_k127_6825004_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1336.0
CMS2_k127_6825004_1 Iron-containing alcohol dehydrogenase K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 526.0
CMS2_k127_6825004_2 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 384.0
CMS2_k127_6825004_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000001885 148.0
CMS2_k127_6866098_0 monooxygenase - - - 2.338e-242 755.0
CMS2_k127_6866098_1 - - - - 0.00000000000000000000003717 107.0
CMS2_k127_6884443_0 Aminotransferase, class I K10907 - - 0.00000000000000000000000000000000009997 138.0
CMS2_k127_6884443_1 Tetratricopeptide repeat - - - 0.000000004132 68.0
CMS2_k127_6885411_0 AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 525.0
CMS2_k127_6885411_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 401.0
CMS2_k127_6907775_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1300.0
CMS2_k127_6907775_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 0.0 1221.0
CMS2_k127_6907775_10 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 344.0
CMS2_k127_6907775_11 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 324.0
CMS2_k127_6907775_12 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 322.0
CMS2_k127_6907775_13 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006105 270.0
CMS2_k127_6907775_14 response regulator receiver K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000000004938 231.0
CMS2_k127_6907775_15 FlhB HrpN YscU SpaS Family K04061 - - 0.00000000000000000000000000000000000000000000008151 171.0
CMS2_k127_6907775_16 Role in flagellar biosynthesis K02420 - - 0.000000000000000000000000000000000000000000001238 166.0
CMS2_k127_6907775_17 FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02417 - - 0.000000000000000000000000000000000000000007922 158.0
CMS2_k127_6907775_18 STAS domain - - - 0.00000000000000000000000000000000000000001658 156.0
CMS2_k127_6907775_19 PFAM flagellar biosynthesis protein, FliO K02418 - - 0.0000000000000000000000000000000000005923 144.0
CMS2_k127_6907775_2 SRP54-type protein, GTPase domain K02404 - - 2.327e-230 716.0
CMS2_k127_6907775_20 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.0000000000000000000000000000008323 121.0
CMS2_k127_6907775_3 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 9.411e-215 668.0
CMS2_k127_6907775_4 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 4.447e-212 662.0
CMS2_k127_6907775_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 453.0
CMS2_k127_6907775_6 Role in flagellar biosynthesis K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 453.0
CMS2_k127_6907775_7 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 449.0
CMS2_k127_6907775_8 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 365.0
CMS2_k127_6907775_9 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 364.0
CMS2_k127_6917106_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1680.0
CMS2_k127_6917106_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.739e-223 695.0
CMS2_k127_6917106_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 577.0
CMS2_k127_6943373_1 Protein of unknown function (DUF3373) - - - 0.0000000007452 70.0
CMS2_k127_6948160_0 Histidine kinase K07717,K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 597.0
CMS2_k127_6948160_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000001087 169.0
CMS2_k127_6948160_2 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000001942 143.0
CMS2_k127_6976086_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 571.0
CMS2_k127_6976086_1 UTRA K02043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 443.0
CMS2_k127_6979509_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.295e-267 825.0
CMS2_k127_6979509_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 1.311e-232 720.0
CMS2_k127_6979509_2 Staphylococcal nuclease homologue - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 492.0
CMS2_k127_6979509_3 TIGRFAM A G-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 363.0
CMS2_k127_6979509_4 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000000000000000000000000000009142 216.0
CMS2_k127_6979509_5 rRNA binding K02909 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0031667,GO:0031668,GO:0031669,GO:0032991,GO:0033554,GO:0034224,GO:0034641,GO:0034645,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0120127,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000006104 166.0
CMS2_k127_6979509_6 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - 0.00000000000000000000000000000000000000000001029 163.0
CMS2_k127_6980847_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 1.58e-281 867.0
CMS2_k127_6980847_1 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 457.0
CMS2_k127_6980847_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000002275 64.0
CMS2_k127_6986785_0 diguanylate cyclase K13590 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 456.0
CMS2_k127_6986785_1 UreD urease accessory protein K03190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 311.0
CMS2_k127_6986785_2 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000000000000000000000000000000000000000000002201 225.0
CMS2_k127_6986785_3 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000001042 167.0
CMS2_k127_6986785_4 Protein of unknown function (DUF2892) - - - 0.000000000000000000000002101 104.0
CMS2_k127_6988630_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 338.0
CMS2_k127_6988630_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 321.0
CMS2_k127_6988630_3 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000002628 171.0
CMS2_k127_6989331_0 Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) K06957 - 2.3.1.193 0.0 1317.0
CMS2_k127_6989331_1 Putative diguanylate phosphodiesterase - - - 1.098e-318 977.0
CMS2_k127_6989331_10 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 428.0
CMS2_k127_6989331_2 HemY protein N-terminus K02498 - - 7.392e-228 709.0
CMS2_k127_6989331_3 argininosuccinate lyase K01755 - 4.3.2.1 5.071e-208 647.0
CMS2_k127_6989331_4 phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 5.372e-195 610.0
CMS2_k127_6989331_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 603.0
CMS2_k127_6989331_7 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009289 558.0
CMS2_k127_6989331_8 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 549.0
CMS2_k127_6989331_9 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 455.0
CMS2_k127_6993917_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1368.0
CMS2_k127_6993917_1 Helicase K03722 - 3.6.4.12 0.0 1275.0
CMS2_k127_6993917_10 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000001309 264.0
CMS2_k127_6993917_11 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000000001773 82.0
CMS2_k127_6993917_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 1.977e-238 739.0
CMS2_k127_6993917_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 3.742e-198 620.0
CMS2_k127_6993917_4 Two component signalling adaptor domain K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 602.0
CMS2_k127_6993917_5 Glycoprotease family K14742 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 424.0
CMS2_k127_6993917_6 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 326.0
CMS2_k127_6993917_7 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 304.0
CMS2_k127_6993917_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 301.0
CMS2_k127_6993917_9 universal stress protein K06149 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003656 263.0
CMS2_k127_7010163_0 Cation transporter/ATPase, N-terminus K01539 - 3.6.3.9 0.0 1602.0
CMS2_k127_7010163_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1462.0
CMS2_k127_7010163_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 585.0
CMS2_k127_7010163_11 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 602.0
CMS2_k127_7010163_12 PFAM SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 544.0
CMS2_k127_7010163_13 Thioesterase domain K02170 - 3.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 501.0
CMS2_k127_7010163_14 FmdE, Molybdenum formylmethanofuran dehydrogenase operon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 499.0
CMS2_k127_7010163_15 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 489.0
CMS2_k127_7010163_16 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 491.0
CMS2_k127_7010163_17 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 472.0
CMS2_k127_7010163_18 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 450.0
CMS2_k127_7010163_19 effector of murein hydrolase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 437.0
CMS2_k127_7010163_2 Protein of unknown function, DUF255 K06888 - - 1.343e-300 935.0
CMS2_k127_7010163_20 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 431.0
CMS2_k127_7010163_22 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 407.0
CMS2_k127_7010163_23 Competence protein - GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007643 374.0
CMS2_k127_7010163_25 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 342.0
CMS2_k127_7010163_26 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 341.0
CMS2_k127_7010163_27 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 312.0
CMS2_k127_7010163_28 cellular response to DNA damage stimulus K07340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008445 261.0
CMS2_k127_7010163_29 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001665 262.0
CMS2_k127_7010163_3 His Kinase A (phosphoacceptor) domain - - - 2.103e-274 848.0
CMS2_k127_7010163_30 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019478,GO:0019752,GO:0043436,GO:0043530,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055130,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 - 0.0000000000000000000000000000000000000000000000000000000000005558 211.0
CMS2_k127_7010163_31 PFAM phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000000000000000000000000000000000000001134 207.0
CMS2_k127_7010163_32 effector of murein hydrolase LrgA K06518 - - 0.00000000000000000000000000000000000000000000000000000000002176 207.0
CMS2_k127_7010163_33 PFAM Small Multidrug Resistance protein K03297 - - 0.0000000000000000000000000000000000000000000000000000001851 195.0
CMS2_k127_7010163_34 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000000000000000000149 140.0
CMS2_k127_7010163_4 transporter, dctM subunit - - - 6.017e-263 813.0
CMS2_k127_7010163_5 Amino acid permease - - - 8.386e-244 758.0
CMS2_k127_7010163_6 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 4.86e-226 704.0
CMS2_k127_7010163_7 Diguanylate cyclase - - - 9.248e-222 691.0
CMS2_k127_7010163_8 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 7.195e-215 668.0
CMS2_k127_7010163_9 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 6.621e-194 606.0
CMS2_k127_7011445_0 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 7.029e-297 915.0
CMS2_k127_7011445_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000001474 251.0
CMS2_k127_7029745_0 Phosphonate K06164 GO:0003674,GO:0003824,GO:0005575,GO:0006793,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019634,GO:0019637,GO:0019700,GO:0032991,GO:0044237,GO:0046434,GO:0061693,GO:0061694,GO:0061695,GO:0071704,GO:1901575,GO:1902494,GO:1904176,GO:1990234 2.7.8.37 2.131e-238 738.0
CMS2_k127_7029745_1 Phosphonate ABC transporter K02042 - - 2.03e-210 655.0
CMS2_k127_7029745_2 ABC transporter K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 522.0
CMS2_k127_7029745_3 Catalyzes the breakage of the C-P bond in alpha-D-ribose 1-methylphosphonate 5-phosphate (PRPn) forming alpha-D-ribose K06163 - 4.7.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 443.0
CMS2_k127_7029745_4 PFAM phosphonate metabolism K06165 - 2.7.8.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 406.0
CMS2_k127_7029745_5 Phosphonate metabolism protein PhnG K06166 - 2.7.8.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005817 278.0
CMS2_k127_7067551_0 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 576.0
CMS2_k127_7067551_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 457.0
CMS2_k127_7067551_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 419.0
CMS2_k127_7067551_3 SH3 domain protein K07184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 414.0
CMS2_k127_7067551_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000005406 223.0
CMS2_k127_7067551_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000000000001027 217.0
CMS2_k127_7067551_6 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000000000000000612 158.0
CMS2_k127_7067551_7 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000638 124.0
CMS2_k127_7078452_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 3.608e-284 877.0
CMS2_k127_7078452_1 Protein of unknown function DUF58 - - - 7.479e-201 628.0
CMS2_k127_7078452_2 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 5.29e-200 624.0
CMS2_k127_7078452_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 560.0
CMS2_k127_7078452_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009668 497.0
CMS2_k127_7078452_5 transcriptional regulator, ArsR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 406.0
CMS2_k127_7088453_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 8.864e-241 744.0
CMS2_k127_7088453_1 short chain amide porin - - - 1.87e-224 697.0
CMS2_k127_7088453_2 transporter, dctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 568.0
CMS2_k127_7088453_3 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 301.0
CMS2_k127_7093979_0 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 496.0
CMS2_k127_7093979_1 Permease YjgP YjgQ K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 381.0
CMS2_k127_720306_0 Diguanylate cyclase - - - 0.0 1524.0
CMS2_k127_720306_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1292.0
CMS2_k127_720306_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 417.0
CMS2_k127_761161_0 TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 0.0 1892.0
CMS2_k127_761161_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.116e-239 741.0
CMS2_k127_761161_11 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001665 234.0
CMS2_k127_761161_12 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002938 226.0
CMS2_k127_761161_13 PFAM Cold-shock protein, DNA-binding - - - 0.000000000000000000000000000000000000000000000000000000000000006188 223.0
CMS2_k127_761161_14 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000987 204.0
CMS2_k127_761161_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000007202 155.0
CMS2_k127_761161_18 Protein of unknown function (DUF2798) - - - 0.000000000000000000000000000001444 121.0
CMS2_k127_761161_19 Bacterial extracellular solute-binding proteins, family 3 - - - 0.00000000000000000002229 100.0
CMS2_k127_761161_2 major facilitator superfamily K05820 - - 6.809e-231 717.0
CMS2_k127_761161_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 1.166e-201 633.0
CMS2_k127_761161_4 Sulfate permease family K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 382.0
CMS2_k127_761161_5 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 368.0
CMS2_k127_761161_6 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 377.0
CMS2_k127_761161_8 Acyl-ACP thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003574 266.0
CMS2_k127_761161_9 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001252 260.0
CMS2_k127_788450_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.995e-212 661.0
CMS2_k127_788450_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 1.239e-207 647.0
CMS2_k127_838880_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.351e-301 924.0
CMS2_k127_838880_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 2.435e-205 640.0
CMS2_k127_838880_11 Succinate dehydrogenase fumarate reductase K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000002401 196.0
CMS2_k127_838880_13 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000004828 149.0
CMS2_k127_838880_2 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006194 531.0
CMS2_k127_838880_3 Sodium Bile acid symporter family K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007442 516.0
CMS2_k127_838880_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 512.0
CMS2_k127_838880_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 494.0
CMS2_k127_838880_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 471.0
CMS2_k127_838880_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006618 454.0
CMS2_k127_838880_8 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 424.0
CMS2_k127_838880_9 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000003269 241.0
CMS2_k127_870114_0 Penicillin-binding protein OB-like domain K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 0.0 1138.0
CMS2_k127_889272_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 536.0
CMS2_k127_889272_1 Pas domain K02488 - 2.7.7.65 0.0000000000000000000000000000008725 141.0
CMS2_k127_896476_0 Diguanylate cyclase - - - 7.743e-198 620.0
CMS2_k127_896476_1 peptidyl-prolyl cis-trans isomerase activity K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000001024 190.0
CMS2_k127_901790_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1217.0
CMS2_k127_901790_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.5e-322 989.0
CMS2_k127_901790_10 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 381.0
CMS2_k127_901790_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 315.0
CMS2_k127_901790_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001063 269.0
CMS2_k127_901790_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 265.0
CMS2_k127_901790_14 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002039 255.0
CMS2_k127_901790_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002028 248.0
CMS2_k127_901790_16 ATP synthase I chain K02116 - - 0.000000000000000000000000000000000000000000000000000000000000002115 218.0
CMS2_k127_901790_17 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000000000000000000006769 181.0
CMS2_k127_901790_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.653e-290 894.0
CMS2_k127_901790_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 3.021e-267 826.0
CMS2_k127_901790_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 549.0
CMS2_k127_901790_5 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 521.0
CMS2_k127_901790_6 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 516.0
CMS2_k127_901790_7 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009678 505.0
CMS2_k127_901790_8 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 480.0
CMS2_k127_901790_9 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 442.0
CMS2_k127_958982_0 DNA helicase K03657 - 3.6.4.12 0.0 1481.0
CMS2_k127_958982_1 abc transporter atp-binding protein K02068 GO:0005575,GO:0005623,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0009987,GO:0016020,GO:0019725,GO:0030003,GO:0042592,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071944,GO:0098771 - 0.0000000000001196 72.0
CMS2_k127_981158_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000001059 213.0
CMS2_k127_9963_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1449.0
CMS2_k127_9963_1 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.0 1233.0
CMS2_k127_9963_2 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 6.999e-232 721.0
CMS2_k127_9963_3 ligase activity - - - 2.55e-229 711.0
CMS2_k127_9963_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02335,K02342,K03654,K03722,K10906 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005515,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008309,GO:0008409,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0035312,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051908,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 2.7.7.7,3.6.4.12 8.466e-222 689.0
CMS2_k127_9963_5 Protein of unknown function (DUF3419) K13622 - - 2.962e-205 640.0
CMS2_k127_9963_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 576.0
CMS2_k127_9963_7 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 424.0
CMS2_k127_9963_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 299.0
CMS2_k127_9963_9 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 282.0
CMS2_k127_996881_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 408.0
CMS2_k127_996881_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000355 46.0