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Overview

ID MAG00426
Name CMS2_bin.37
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Alphaproteobacteria
Order Kiloniellales
Family CECT-8803
Genus JARRJC01
Species
Assembly information
Completeness (%) 97.06
Contamination (%) 0.83
GC content (%) 67.0
N50 (bp) 6,295
Genome size (bp) 2,765,331

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2874

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1016668_0 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 2.604e-314 985.0
CMS2_k127_1016668_1 Cystathionine beta-synthase K01697 - 4.2.1.22 7.604e-204 644.0
CMS2_k127_1016668_2 Penicillin amidase K01434 - 3.5.1.11 1.236e-200 651.0
CMS2_k127_1016668_3 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01758 - 4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 578.0
CMS2_k127_1016668_4 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 546.0
CMS2_k127_1016668_5 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000006435 254.0
CMS2_k127_1016668_6 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.000000000000000000000000000000000000000000000000000000000000003604 219.0
CMS2_k127_1016668_7 RDD family - - - 0.000000000000000000000000002173 118.0
CMS2_k127_1016668_8 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000000000000002902 97.0
CMS2_k127_1020356_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 582.0
CMS2_k127_1020356_1 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 485.0
CMS2_k127_1020356_2 helix_turn_helix ASNC type K03719 - - 0.0000000000000000000000000000000000000000000000000000000000000002043 223.0
CMS2_k127_1020356_3 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000002716 227.0
CMS2_k127_1034094_0 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 360.0
CMS2_k127_1034094_1 DREV methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001028 214.0
CMS2_k127_1034094_2 Domain of unknown function DUF108 - - - 0.00000000000000000000000000000000000002003 144.0
CMS2_k127_1036807_0 belongs to the aldehyde dehydrogenase family - - - 3.966e-255 792.0
CMS2_k127_1036807_1 COG1108 ABC-type Mn2 Zn2 transport systems, permease components K02075,K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 323.0
CMS2_k127_1036807_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 302.0
CMS2_k127_1036807_3 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 310.0
CMS2_k127_1036807_4 Zinc-uptake complex component A periplasmic K09815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006793 274.0
CMS2_k127_1036807_5 Belongs to the Fur family K09823 - - 0.0000000000000000000000000000000000000000000000000003956 189.0
CMS2_k127_1037595_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 2.956e-202 643.0
CMS2_k127_1037595_1 Acyl-CoA dehydrogenase, C-terminal domain K19966 - 3.13.1.4 5.17e-202 633.0
CMS2_k127_1037595_2 Protein conserved in bacteria K09914 - - 0.000000000000000000000000000000000000000000000000007414 191.0
CMS2_k127_1092840_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.495e-288 895.0
CMS2_k127_1092840_1 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 334.0
CMS2_k127_1092840_2 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000131 257.0
CMS2_k127_1092840_3 Uncharacterized protein conserved in bacteria (DUF2125) - - - 0.0000000271 60.0
CMS2_k127_1096714_0 Bacterial extracellular solute-binding protein K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 563.0
CMS2_k127_1096714_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023,K20549 - 4.2.1.156,4.2.1.42,5.1.2.2,5.5.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 390.0
CMS2_k127_1096714_2 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 362.0
CMS2_k127_1096714_4 helix_turn_helix, Lux Regulon K14987 - - 0.00000000000006101 76.0
CMS2_k127_1096714_5 Part of the ABC transporter complex TagGH involved in teichoic acids export. Responsible for energy coupling to the transport system K09693 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0015921,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:1901264,GO:1901505 3.6.3.40 0.00000000007741 65.0
CMS2_k127_1101910_0 Permease family K03458 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 598.0
CMS2_k127_1101910_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 470.0
CMS2_k127_1101910_2 Binding-protein-dependent transport system inner membrane component K17323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 422.0
CMS2_k127_1101910_3 small integral membrane protein - - - 0.000000000000000000000000000000000004447 140.0
CMS2_k127_1110863_0 FAD binding domain K00103,K16653 - 1.1.3.8,1.1.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006705 336.0
CMS2_k127_1110863_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000001014 223.0
CMS2_k127_1126186_0 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 392.0
CMS2_k127_1126186_1 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 346.0
CMS2_k127_1126186_2 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 334.0
CMS2_k127_1126186_3 COG3474 Cytochrome c2 K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 313.0
CMS2_k127_1126186_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 292.0
CMS2_k127_1127499_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 347.0
CMS2_k127_1127499_1 proteins of the AP superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002881 273.0
CMS2_k127_1127499_2 ChrR Cupin-like domain K07167 - - 0.00000000000000000000000000000000000000000000000000000000000000002564 232.0
CMS2_k127_1127499_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000663 220.0
CMS2_k127_1127499_4 clavaminate synthase activity K00471 - 1.14.11.1 0.00000000000000000000000000000000000000000009222 168.0
CMS2_k127_1127499_5 Type IV leader peptidase family K02278 - 3.4.23.43 0.00000000000000000516 91.0
CMS2_k127_1174878_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.564e-313 973.0
CMS2_k127_1174878_1 COG1593 TRAP-type C4-dicarboxylate transport system large permease component K11690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 594.0
CMS2_k127_1174878_10 flagellar motor protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004285 282.0
CMS2_k127_1174878_11 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000000001352 219.0
CMS2_k127_1174878_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000003658 186.0
CMS2_k127_1174878_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000002636 156.0
CMS2_k127_1174878_14 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.00000000000000000000000000000000000001204 151.0
CMS2_k127_1174878_15 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000001431 88.0
CMS2_k127_1174878_16 COG2885 outer membrane protein and related peptidoglycan-associated (lipo)proteins - - - 0.00000000002315 75.0
CMS2_k127_1174878_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 520.0
CMS2_k127_1174878_3 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 511.0
CMS2_k127_1174878_4 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 488.0
CMS2_k127_1174878_5 MotA TolQ ExbB proton channel family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 439.0
CMS2_k127_1174878_6 Protein conserved in bacteria K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 402.0
CMS2_k127_1174878_7 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 389.0
CMS2_k127_1174878_8 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 344.0
CMS2_k127_1174878_9 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 306.0
CMS2_k127_1192997_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 1.121e-290 905.0
CMS2_k127_1192997_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 1.102e-213 674.0
CMS2_k127_1192997_2 Serine dehydrogenase proteinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005395 329.0
CMS2_k127_1192997_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 321.0
CMS2_k127_1192997_4 Protein of unknown function (DUF1134) - - - 0.00000000000000000000000000000000000000000000000000000000000008741 227.0
CMS2_k127_1192997_5 helix_turn_helix ASNC type K05800 - - 0.0000000000000000000000000000000000000000000000000000000003594 209.0
CMS2_k127_1192997_6 NADH flavin oxidoreductase NADH oxidase K21833 - - 0.000000000000000000000000000000000000000000413 159.0
CMS2_k127_1192997_7 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000001131 134.0
CMS2_k127_1192997_8 - - - - 0.000000000000000000207 91.0
CMS2_k127_1205958_0 Cytochrome c-type biogenesis protein K02198 - - 2.422e-301 945.0
CMS2_k127_1205958_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 505.0
CMS2_k127_1205958_10 Redoxin K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000001975 226.0
CMS2_k127_1205958_11 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000001413 188.0
CMS2_k127_1205958_12 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000001025 175.0
CMS2_k127_1205958_13 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000000000000000000000000000000000000000006037 168.0
CMS2_k127_1205958_14 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000008229 149.0
CMS2_k127_1205958_15 branched-chain amino acid K01996 - - 0.000000000000000000000000000000009237 127.0
CMS2_k127_1205958_16 phosphorelay sensor kinase activity - - - 0.000000000000000000005942 97.0
CMS2_k127_1205958_17 Protein of unknown function (DUF3108) - - - 0.000000000000001238 87.0
CMS2_k127_1205958_18 His Kinase A (phosphoacceptor) domain - - - 0.000000000000003315 88.0
CMS2_k127_1205958_19 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.00000001208 60.0
CMS2_k127_1205958_2 AAA domain, putative AbiEii toxin, Type IV TA system K02028,K10021,K10025 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 380.0
CMS2_k127_1205958_3 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 363.0
CMS2_k127_1205958_4 Bacterial periplasmic substrate-binding proteins K09997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008778 314.0
CMS2_k127_1205958_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 296.0
CMS2_k127_1205958_6 Stf0 sulphotransferase K21014 - 2.8.2.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 297.0
CMS2_k127_1205958_7 Binding-protein-dependent transport system inner membrane component K02029,K10019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 291.0
CMS2_k127_1205958_8 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001456 273.0
CMS2_k127_1205958_9 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000236 258.0
CMS2_k127_1224730_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 4.041e-294 909.0
CMS2_k127_1224730_1 Resolvase K06400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 593.0
CMS2_k127_1224730_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 497.0
CMS2_k127_1224730_3 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001152 287.0
CMS2_k127_1224730_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000009652 272.0
CMS2_k127_1224730_6 Transglycosylase SLT domain - - - 0.00002366 50.0
CMS2_k127_1235151_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 544.0
CMS2_k127_1235151_1 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000008923 68.0
CMS2_k127_1238613_0 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 419.0
CMS2_k127_1238613_1 Protein of unknown function, DUF393 - - - 0.0000000000000000000000000009612 115.0
CMS2_k127_1240565_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 578.0
CMS2_k127_1240565_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 546.0
CMS2_k127_1240565_10 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.000001563 54.0
CMS2_k127_1240565_11 - - - - 0.0003521 45.0
CMS2_k127_1240565_2 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 344.0
CMS2_k127_1240565_3 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 334.0
CMS2_k127_1240565_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000896 228.0
CMS2_k127_1240565_5 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000003655 228.0
CMS2_k127_1240565_6 Uncharacterised protein family (UPF0262) - - - 0.000000000000000000000000000000000000000000000000000000000000007275 222.0
CMS2_k127_1240565_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000001074 143.0
CMS2_k127_1240565_8 Protein of unknown function (DUF2948) - - - 0.0000000000000000000000000000006177 140.0
CMS2_k127_1240565_9 Ribonuclease E/G family - - - 0.000000000000000000008476 105.0
CMS2_k127_1258909_0 COG0471 Di- and tricarboxylate transporters - - - 1.766e-221 701.0
CMS2_k127_1258909_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 559.0
CMS2_k127_1258909_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 435.0
CMS2_k127_1258909_3 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000001484 196.0
CMS2_k127_1260188_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 435.0
CMS2_k127_1260188_1 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009821 351.0
CMS2_k127_1260188_2 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 319.0
CMS2_k127_1260188_3 serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 304.0
CMS2_k127_1260188_4 transcriptional regulator K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000000163 235.0
CMS2_k127_1260188_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000003564 154.0
CMS2_k127_1279754_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 576.0
CMS2_k127_1279754_1 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000003535 141.0
CMS2_k127_1279754_2 invasion associated locus B - - - 0.000000001873 66.0
CMS2_k127_1332372_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000006625 223.0
CMS2_k127_1332372_1 - - - - 0.00000000000000000000000000000000000000000000184 172.0
CMS2_k127_1332372_2 - - - - 0.00000000000000000000000000000000001198 140.0
CMS2_k127_1335287_0 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 394.0
CMS2_k127_1335287_1 COG2513 PEP phosphonomutase and related enzymes K01841,K03417 - 4.1.3.30,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 294.0
CMS2_k127_1335287_2 PFAM Mandelate racemase muconate lactonizing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 284.0
CMS2_k127_1335287_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000005061 166.0
CMS2_k127_1335287_4 ornithine cyclodeaminase activity K01750,K16182 - 4.3.1.12 0.00000000000000000000000000000000000002453 156.0
CMS2_k127_1337325_0 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.00000000000000000000000000000000000000006075 153.0
CMS2_k127_1337325_1 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000312 127.0
CMS2_k127_1337325_2 EamA-like transporter family - - - 0.00000007717 57.0
CMS2_k127_1351624_0 metal ion transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009929 557.0
CMS2_k127_1351624_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000004377 181.0
CMS2_k127_1351624_2 - - - - 0.000000002036 61.0
CMS2_k127_1355171_0 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009834 568.0
CMS2_k127_1355171_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 317.0
CMS2_k127_1355171_2 ABC transporter transmembrane region K02021 - - 0.000000000000000002819 88.0
CMS2_k127_1363123_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.409e-269 835.0
CMS2_k127_1363123_1 enoyl-CoA hydratase K15513 - 4.1.2.44 1.807e-261 816.0
CMS2_k127_1363123_2 phenylacetic acid degradation protein K02618 - 1.2.1.91,3.3.2.12 3.897e-213 677.0
CMS2_k127_1363123_3 Oxidoreductase FAD-binding domain K15511 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 583.0
CMS2_k127_1363123_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 327.0
CMS2_k127_1363123_5 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001479 277.0
CMS2_k127_1363123_6 Thioesterase - - - 0.0000000000000000000000000000000000001513 151.0
CMS2_k127_1363123_7 Domain of unknown function (DUF309) K09763 - - 0.00000000000002858 83.0
CMS2_k127_1372415_0 Adenylate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 349.0
CMS2_k127_1372415_1 MlrC C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001752 268.0
CMS2_k127_1377160_0 Tripartite tricarboxylate transporter TctA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 473.0
CMS2_k127_1377160_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 456.0
CMS2_k127_1377160_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 408.0
CMS2_k127_1377160_3 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 346.0
CMS2_k127_1377160_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 317.0
CMS2_k127_1377160_5 FCD - - - 0.000000000000000000000000000000000000000000000000000000004436 208.0
CMS2_k127_1377160_6 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000000000007331 151.0
CMS2_k127_1377160_7 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.00000000000000000000000001087 115.0
CMS2_k127_1377804_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.163e-218 681.0
CMS2_k127_1377804_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 320.0
CMS2_k127_1377804_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005759 292.0
CMS2_k127_1377804_3 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 297.0
CMS2_k127_1377804_4 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 284.0
CMS2_k127_1377804_5 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002866 276.0
CMS2_k127_1377804_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000004493 232.0
CMS2_k127_1377804_7 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000001358 216.0
CMS2_k127_1377804_8 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000003626 138.0
CMS2_k127_1377804_9 VanZ like family - - - 0.000000000000000000000000001309 120.0
CMS2_k127_1411631_0 Probable molybdopterin binding domain K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006238 576.0
CMS2_k127_1411631_1 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 511.0
CMS2_k127_1411631_2 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 465.0
CMS2_k127_1411631_3 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 382.0
CMS2_k127_1411631_4 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000769 267.0
CMS2_k127_1411631_5 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000002563 188.0
CMS2_k127_1411631_6 XdhC and CoxI family - - - 0.000000000000000000000000000000000000001575 151.0
CMS2_k127_1416962_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 336.0
CMS2_k127_1416962_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000144 273.0
CMS2_k127_1416962_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000001094 125.0
CMS2_k127_1416962_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000002883 115.0
CMS2_k127_1430113_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08351 - - 2.992e-298 934.0
CMS2_k127_1430113_1 Polyphosphate kinase 2 (PPK2) K22468 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008976,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0044237 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009947 440.0
CMS2_k127_1430113_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 338.0
CMS2_k127_1430113_3 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008907 323.0
CMS2_k127_1430113_4 FCD - - - 0.00000000000000000000000000000000000000000000000000002799 208.0
CMS2_k127_1430113_5 Domain of unknown function (DUF4915) - - - 0.0000000003672 62.0
CMS2_k127_1430113_6 FAD dependent oxidoreductase - - - 0.00004522 49.0
CMS2_k127_1433995_0 PFAM Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 396.0
CMS2_k127_1433995_1 Serine phosphatase RsbU, regulator of sigma subunit - - - 0.0000003057 58.0
CMS2_k127_1443795_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 8.14e-263 829.0
CMS2_k127_1444307_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 436.0
CMS2_k127_1444307_1 COG1177 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.000000000000000000000000000000000000004164 147.0
CMS2_k127_1444307_2 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K00317 - 1.5.8.1,1.5.8.2 0.00000000000000000002426 93.0
CMS2_k127_1451129_0 Sugar (and other) transporter - - - 8.359e-205 643.0
CMS2_k127_1451129_1 Aldehyde-activating protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000006502 232.0
CMS2_k127_1451129_2 NAD binding domain of 6-phosphogluconate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000001994 225.0
CMS2_k127_1451129_3 Membrane - - - 0.00000000000000000000000002582 114.0
CMS2_k127_1479258_0 phosphoenolpyruvate carboxylase activity K01595 - 4.1.1.31 2.554e-218 706.0
CMS2_k127_1479258_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 579.0
CMS2_k127_1479258_2 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029,K21147 - 2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 374.0
CMS2_k127_1479258_3 Methyltransferase domain - - - 0.00000000000000000000000000002192 123.0
CMS2_k127_1488803_0 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000002867 175.0
CMS2_k127_1488803_1 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000000000000000000000001807 172.0
CMS2_k127_1488803_2 oxidoreductase FAD NAD(P)-binding domain protein K14581 - 1.18.1.7 0.000000000000000000000000000000000000000000001211 178.0
CMS2_k127_1488803_3 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000008367 119.0
CMS2_k127_1491185_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 377.0
CMS2_k127_1491185_1 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 285.0
CMS2_k127_1494578_0 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 485.0
CMS2_k127_1494578_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 456.0
CMS2_k127_1494578_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000001352 170.0
CMS2_k127_1500531_0 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 2.241e-252 799.0
CMS2_k127_1500531_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 5.003e-243 754.0
CMS2_k127_1500531_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 477.0
CMS2_k127_1500531_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 329.0
CMS2_k127_1500531_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000001813 160.0
CMS2_k127_1500531_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0001945 46.0
CMS2_k127_150874_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K00317 - 1.5.8.1,1.5.8.2 6.301e-223 730.0
CMS2_k127_150874_1 Flavin containing amine oxidoreductase - - - 3.362e-212 671.0
CMS2_k127_150874_10 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 327.0
CMS2_k127_150874_11 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 297.0
CMS2_k127_150874_12 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072,K11076 - 3.6.3.31 0.000000000000000000000000000000000000000008063 155.0
CMS2_k127_150874_13 Acetyltransferase (GNAT) domain - - - 0.00000000003083 65.0
CMS2_k127_150874_2 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 572.0
CMS2_k127_150874_3 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 524.0
CMS2_k127_150874_4 COG0687 Spermidine putrescine-binding periplasmic protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 517.0
CMS2_k127_150874_5 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 445.0
CMS2_k127_150874_6 COG1176 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 381.0
CMS2_k127_150874_7 COG1177 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 353.0
CMS2_k127_150874_8 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 345.0
CMS2_k127_150874_9 Belongs to the GcvT family K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 362.0
CMS2_k127_1511392_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 3.309e-281 876.0
CMS2_k127_1511392_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 2.033e-232 726.0
CMS2_k127_1511392_2 Chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 354.0
CMS2_k127_1511392_3 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 300.0
CMS2_k127_1511392_4 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000001357 232.0
CMS2_k127_153197_0 synthetase - - - 2.345e-217 685.0
CMS2_k127_153197_1 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 486.0
CMS2_k127_153197_2 HemY protein N-terminus K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 393.0
CMS2_k127_153197_3 Protein of unknown function (DUF1513) K09947 - - 0.000000000000000000000000000000000000000000000000000000000000007278 225.0
CMS2_k127_153197_4 Mitochondrial inner membrane protein - - - 0.0000000000000000008293 97.0
CMS2_k127_153197_5 Iron-regulated protein K07231 - - 0.000000001543 68.0
CMS2_k127_1554340_0 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 1.604e-259 806.0
CMS2_k127_1554340_1 NADH ubiquinone oxidoreductase subunit 5 (chain L) multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.456e-206 649.0
CMS2_k127_1554340_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 605.0
CMS2_k127_1554340_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 327.0
CMS2_k127_1554340_4 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 300.0
CMS2_k127_1554340_5 hydrolase of the metallo-beta-lactamase superfamily K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000005641 246.0
CMS2_k127_1559963_0 membrane - - - 0.000000000000000000000000000000000000000000008762 167.0
CMS2_k127_1559963_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000001365 164.0
CMS2_k127_1559963_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000001204 146.0
CMS2_k127_1559963_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000008483 111.0
CMS2_k127_1575556_0 PFAM Penicillin binding protein transpeptidase domain K05366 - 2.4.1.129,3.4.16.4 0.0 1014.0
CMS2_k127_1575556_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.161e-309 972.0
CMS2_k127_1575556_2 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 6.209e-200 644.0
CMS2_k127_1575556_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 524.0
CMS2_k127_1575556_4 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 389.0
CMS2_k127_1575556_5 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 339.0
CMS2_k127_1575556_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009412 281.0
CMS2_k127_1575556_7 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000002657 265.0
CMS2_k127_1575556_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000005367 195.0
CMS2_k127_1575556_9 Hemimethylated DNA-binding protein YccV like K11940 - - 0.0000000000000000000000000000000000000000000017 172.0
CMS2_k127_1591081_0 Molecular chaperone. Has ATPase activity K04079 - - 2.803e-239 759.0
CMS2_k127_1591081_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000002757 148.0
CMS2_k127_1594476_0 COG0044 Dihydroorotase and related cyclic amidohydrolases K01465 - 3.5.2.3 1.826e-202 640.0
CMS2_k127_1594476_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 1.553e-198 623.0
CMS2_k127_1594476_2 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000159 239.0
CMS2_k127_1594476_3 - - - - 0.000000000000000000000000000000000000008263 149.0
CMS2_k127_1594476_4 Cupin domain - - - 0.0000000000000000000000000001509 119.0
CMS2_k127_1594476_5 Transcriptional - - - 0.00000000000000005709 85.0
CMS2_k127_1594476_6 Belongs to the GcvT family K06980 - - 0.000000000000002017 83.0
CMS2_k127_1634570_0 Oxidoreductase family, NAD-binding Rossmann fold K00035 - 1.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 442.0
CMS2_k127_1634570_1 Belongs to the IlvD Edd family K13875,K22186 - 4.2.1.25,4.2.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 361.0
CMS2_k127_1634570_2 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004626 283.0
CMS2_k127_1634570_3 KDPG and KHG aldolase K01631 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008674,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0019520,GO:0019583,GO:0019584,GO:0019752,GO:0032787,GO:0034192,GO:0034194,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0046176,GO:0046395,GO:0071704,GO:0072329,GO:1901575 4.1.2.21 0.000000000000000000000000000000000000000000000000000000000000000000005522 245.0
CMS2_k127_1634570_4 Converts alpha-aldose to the beta-anomer K01785 GO:0003674,GO:0003824,GO:0004034,GO:0005975,GO:0005996,GO:0006006,GO:0006012,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.1.3.3 0.00000000000000004721 90.0
CMS2_k127_1637254_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1420.0
CMS2_k127_1637254_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004453 443.0
CMS2_k127_1637254_10 Protein of unknown function (DUF3305) - - - 0.0000000000000000000000000000000000000000000000001362 183.0
CMS2_k127_1637254_11 Protein of unknown function (DUF3306) - - - 0.000000000000000000000000002987 123.0
CMS2_k127_1637254_12 lipopolysaccharide metabolic process K19302 - 3.6.1.27 0.0000000000000003659 88.0
CMS2_k127_1637254_13 TIGRFAM formate dehydrogenase region TAT target - - - 0.00000006016 57.0
CMS2_k127_1637254_14 - - - - 0.0004295 47.0
CMS2_k127_1637254_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 411.0
CMS2_k127_1637254_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 405.0
CMS2_k127_1637254_4 Rhamnan synthesis protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003938 282.0
CMS2_k127_1637254_5 Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002532 278.0
CMS2_k127_1637254_6 Nitrate reductase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006787 262.0
CMS2_k127_1637254_7 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000005167 261.0
CMS2_k127_1637254_8 glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000007827 242.0
CMS2_k127_1637254_9 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008831,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016491,GO:0016614,GO:0016616,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0045226,GO:0046379,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000001342 254.0
CMS2_k127_1641949_0 Belongs to the thiolase family K00626 - 2.3.1.9 3.152e-207 649.0
CMS2_k127_1641949_1 N-methylhydantoinase A acetone carboxylase, beta subunit - - - 1.263e-198 640.0
CMS2_k127_1641949_2 alpha/beta hydrolase fold K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 428.0
CMS2_k127_1641949_3 Acetoacetyl-CoA reductase K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 382.0
CMS2_k127_1641949_4 Putative amidoligase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008107 295.0
CMS2_k127_1641949_5 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003112 281.0
CMS2_k127_1641949_6 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007026 278.0
CMS2_k127_1641949_7 Polyhydroxyalkanoate synthesis repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002098 253.0
CMS2_k127_1641949_8 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000000000000000000002703 245.0
CMS2_k127_1641949_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000001492 195.0
CMS2_k127_165679_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 2.873e-240 748.0
CMS2_k127_165679_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 541.0
CMS2_k127_165679_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K00627 - 1.2.4.1,2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 482.0
CMS2_k127_165679_3 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 419.0
CMS2_k127_165679_4 Oligoketide cyclase lipid transport protein K18588 - - 0.00000000000000000000000000000000000000000000000000000000000000335 221.0
CMS2_k127_165679_5 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000009785 204.0
CMS2_k127_165679_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000003302 198.0
CMS2_k127_165679_7 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000005922 185.0
CMS2_k127_165679_8 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000001994 185.0
CMS2_k127_165679_9 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000001911 102.0
CMS2_k127_1671314_0 Belongs to the DapA family K13876 - 4.2.1.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 499.0
CMS2_k127_1671314_1 Converts alpha-aldose to the beta-anomer K01785 GO:0003674,GO:0003824,GO:0004034,GO:0005975,GO:0005996,GO:0006006,GO:0006012,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019318,GO:0019320,GO:0019388,GO:0033499,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 386.0
CMS2_k127_1671314_2 SMP-30/Gluconolaconase/LRE-like region K13874,K22217 - 3.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 340.0
CMS2_k127_1689521_0 COG0513 Superfamily II DNA and RNA helicases K17675 - 3.6.4.13 6.003e-282 891.0
CMS2_k127_1689521_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000001172 178.0
CMS2_k127_1689521_2 S4 domain K04762 - - 0.000000000000000000000000003845 112.0
CMS2_k127_169011_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 543.0
CMS2_k127_169011_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 425.0
CMS2_k127_169011_2 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007364 327.0
CMS2_k127_169011_3 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 308.0
CMS2_k127_169011_4 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004001 258.0
CMS2_k127_169011_5 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000008338 193.0
CMS2_k127_1706659_0 - - - - 0.0000000000000000000000000000000000000000000000000000000002626 210.0
CMS2_k127_1706659_1 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000009777 208.0
CMS2_k127_1706659_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000008885 204.0
CMS2_k127_1706659_3 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000002139 128.0
CMS2_k127_1706659_4 Sel1-like repeats. K07126 - - 0.0000000000000000000000000000000237 138.0
CMS2_k127_1706659_5 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000009434 123.0
CMS2_k127_1706659_6 - - - - 0.00000000000000000000001513 106.0
CMS2_k127_1706659_7 Domain of unknown function (DUF4154) - - - 0.000000008648 64.0
CMS2_k127_1709655_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.781e-197 624.0
CMS2_k127_1709655_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 597.0
CMS2_k127_1709655_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 571.0
CMS2_k127_1709655_3 FAD dependent oxidoreductase K09471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 513.0
CMS2_k127_1709655_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000008861 241.0
CMS2_k127_1714161_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.488e-226 711.0
CMS2_k127_1714161_1 Stimulus-sensing domain K14980 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 552.0
CMS2_k127_1714161_2 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K14981 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 392.0
CMS2_k127_1714161_3 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000000000000000000000006139 151.0
CMS2_k127_1714161_4 COG1493 Serine kinase of the HPr protein, regulates carbohydrate metabolism K06023 - - 0.00000000000000000000000000000000000001868 148.0
CMS2_k127_1720309_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 4.76e-320 1000.0
CMS2_k127_1720309_1 PFAM Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007163 584.0
CMS2_k127_1720309_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 433.0
CMS2_k127_1720309_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 398.0
CMS2_k127_1720309_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 332.0
CMS2_k127_1720309_5 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 317.0
CMS2_k127_1720309_6 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000003519 220.0
CMS2_k127_1720309_7 Belongs to the BI1 family K06890 - - 0.0000000000000000000000000000000000000000000000001402 182.0
CMS2_k127_1722642_0 spermidine putrescine K02054 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 481.0
CMS2_k127_1722642_1 ABC-type spermidine putrescine transport system, permease component II K02053 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 423.0
CMS2_k127_1751584_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 414.0
CMS2_k127_1751584_1 COG2873 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 316.0
CMS2_k127_1751584_2 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000007467 229.0
CMS2_k127_175223_0 Bacterial extracellular solute-binding protein K02027 - - 1.994e-251 779.0
CMS2_k127_175223_1 Belongs to the aldehyde dehydrogenase family - - - 1.292e-240 753.0
CMS2_k127_175223_2 ABC-type dipeptide transport system, periplasmic component - - - 1.448e-196 627.0
CMS2_k127_175223_3 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 569.0
CMS2_k127_175223_4 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 558.0
CMS2_k127_175223_5 ABC-type sugar transport systems permease components K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006631 537.0
CMS2_k127_175223_6 oxidase, subunit K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 528.0
CMS2_k127_175223_7 ABC-type sugar transport system, permease component K02026,K10229 - - 0.00000000000000000000000000000000000000006527 167.0
CMS2_k127_1762941_0 Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 367.0
CMS2_k127_1762941_1 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 306.0
CMS2_k127_1762941_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004215 271.0
CMS2_k127_1765856_0 Domain of unknown function (DUF3390) K18929 - - 6.506e-222 695.0
CMS2_k127_1765856_1 membrane-bound lytic murein transglycosylase K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 407.0
CMS2_k127_1765856_2 (Fe-S) oxidoreductase K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 385.0
CMS2_k127_1765856_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000005583 223.0
CMS2_k127_1782305_0 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00000000000000000000000000000000008228 146.0
CMS2_k127_1782305_2 Serine aminopeptidase, S33 - - - 0.000000000002391 71.0
CMS2_k127_1782305_3 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00001435 50.0
CMS2_k127_1794333_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 2.409e-257 809.0
CMS2_k127_1794333_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 610.0
CMS2_k127_1794333_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 369.0
CMS2_k127_1794333_3 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 323.0
CMS2_k127_1794333_4 PFAM Methyltransferase type - - - 0.00000000000000000000000000000000000000000000000000000000000006195 218.0
CMS2_k127_1794333_5 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000009552 196.0
CMS2_k127_1794333_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000002883 139.0
CMS2_k127_1794333_7 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000009481 126.0
CMS2_k127_1823838_0 Bacterial protein of unknown function (DUF839) K07093 - - 1.113e-272 854.0
CMS2_k127_1823838_1 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 528.0
CMS2_k127_1835608_0 HpcH/HpaI aldolase/citrate lyase family K08691 - 4.1.3.24,4.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 440.0
CMS2_k127_1835608_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 438.0
CMS2_k127_1851248_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 1.838e-283 879.0
CMS2_k127_1851248_1 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 299.0
CMS2_k127_1851248_2 Haemolysin-III related K11068 - - 0.0000000000000000000000000000002053 128.0
CMS2_k127_1853640_0 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 474.0
CMS2_k127_1853640_1 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000003355 267.0
CMS2_k127_1871000_0 Protein of unknown function (DUF3422) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 486.0
CMS2_k127_1871000_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000003081 245.0
CMS2_k127_1881139_0 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000624 304.0
CMS2_k127_1881139_1 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000005173 158.0
CMS2_k127_1881139_2 Protein of unknown function (DUF3095) - - - 0.000000000000000000000000000000000000000003658 159.0
CMS2_k127_1884127_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 466.0
CMS2_k127_1884127_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 319.0
CMS2_k127_1884127_2 Aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000001685 104.0
CMS2_k127_1887249_0 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009904 502.0
CMS2_k127_1887249_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 338.0
CMS2_k127_1887249_2 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.0000000000000000000000000000000000004274 151.0
CMS2_k127_1896931_0 HELICc2 K03722 - 3.6.4.12 0.0 1017.0
CMS2_k127_1896931_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 534.0
CMS2_k127_1896931_2 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 321.0
CMS2_k127_1896931_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 320.0
CMS2_k127_1898097_0 RimK-like ATP-grasp domain - - - 7.321e-226 714.0
CMS2_k127_1898097_1 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 527.0
CMS2_k127_1898097_2 COG0367 Asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000003176 246.0
CMS2_k127_18997_0 Cell division protein FtsI penicillin-binding protein 2 K05515 - 3.4.16.4 1.328e-253 797.0
CMS2_k127_18997_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.462e-212 664.0
CMS2_k127_18997_2 Rod shape-determining protein MreB K03569 - - 7.142e-201 628.0
CMS2_k127_18997_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 514.0
CMS2_k127_18997_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 426.0
CMS2_k127_18997_5 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008364 256.0
CMS2_k127_18997_6 shape-determining protein K03571 - - 0.0000000000000000000000000000000000000000857 168.0
CMS2_k127_1906031_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000005217 264.0
CMS2_k127_1906031_1 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000006105 155.0
CMS2_k127_1906031_2 - - - - 0.0000008644 58.0
CMS2_k127_1906277_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 353.0
CMS2_k127_1906277_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000882 279.0
CMS2_k127_1907940_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 588.0
CMS2_k127_1907940_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 315.0
CMS2_k127_1907940_2 COG2186 Transcriptional regulators K05799,K14348 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008016 293.0
CMS2_k127_1917100_0 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 329.0
CMS2_k127_1917100_1 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001461 261.0
CMS2_k127_1918648_0 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 492.0
CMS2_k127_1918648_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 441.0
CMS2_k127_1918648_2 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K02049,K10831 - 3.6.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 411.0
CMS2_k127_1918648_3 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 388.0
CMS2_k127_1918648_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 379.0
CMS2_k127_1918648_5 Fumarylacetoacetate (FAA) hydrolase family K16165 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0008948,GO:0016787,GO:0016822,GO:0016823,GO:0016829,GO:0016830,GO:0016831,GO:0018773,GO:0031974,GO:0031981,GO:0034545,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0070013 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 364.0
CMS2_k127_1918648_6 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 365.0
CMS2_k127_1918648_7 LVIVD repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 350.0
CMS2_k127_1918648_8 FCD K13637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 286.0
CMS2_k127_1918648_9 membrane transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000006404 242.0
CMS2_k127_1923333_0 Belongs to the IlvD Edd family K22186 - 4.2.1.82 3.672e-299 927.0
CMS2_k127_1923333_1 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K01826 - 5.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 400.0
CMS2_k127_1923333_2 epimerase dehydratase K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 366.0
CMS2_k127_1923333_3 Short-chain dehydrogenase reductase SDR K21883 - 1.1.1.401 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 342.0
CMS2_k127_1923333_4 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000003852 253.0
CMS2_k127_1923333_5 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K22229 - 1.1.1.215 0.000000000004158 66.0
CMS2_k127_1924796_0 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 365.0
CMS2_k127_1924796_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 329.0
CMS2_k127_1924796_2 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000001186 239.0
CMS2_k127_1924796_4 - - - - 0.0000000000000000000000000000000000000000000004843 173.0
CMS2_k127_1930612_0 Transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006848 281.0
CMS2_k127_1930612_1 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009079 278.0
CMS2_k127_1930612_2 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000002197 217.0
CMS2_k127_1931451_0 single-stranded-DNA-specific exonuclease recJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 481.0
CMS2_k127_1931451_1 COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins K11532 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 313.0
CMS2_k127_1942829_0 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007384 270.0
CMS2_k127_1942829_1 Putative 2OG-Fe(II) oxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002237 255.0
CMS2_k127_1942829_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000334 252.0
CMS2_k127_1942829_3 PFAM Transcription elongation factor, GreA GreB - - - 0.000000000000000000000000000000000000000000000000218 182.0
CMS2_k127_1942829_4 Evidence 4 Homologs of previously reported genes of K09700 - - 0.0000000000000000000000000000000006347 133.0
CMS2_k127_1942829_5 cytochrome c - - - 0.000000000003095 73.0
CMS2_k127_1942829_6 Sporulation related domain - - - 0.0000000005706 65.0
CMS2_k127_1977207_0 Trap-type c4-dicarboxylate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 432.0
CMS2_k127_1977207_1 COG0665 Glycine D-amino acid oxidases (deaminating) K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000001293 183.0
CMS2_k127_1977207_2 transport system, small permease component - - - 0.00000000000000000000000000000000000000000003933 164.0
CMS2_k127_1988488_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 558.0
CMS2_k127_1988488_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000002829 134.0
CMS2_k127_1995467_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.255e-229 715.0
CMS2_k127_1995467_1 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 - 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 447.0
CMS2_k127_1995467_2 Modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 424.0
CMS2_k127_1995467_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006325 270.0
CMS2_k127_1995467_4 Cytochrome C1 family K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000152 264.0
CMS2_k127_1995467_5 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000004717 205.0
CMS2_k127_2017956_0 Na H antiporter K03316 - - 1.245e-282 888.0
CMS2_k127_2017956_1 COG0747 ABC-type dipeptide transport system, periplasmic component K02035 - - 1.074e-213 676.0
CMS2_k127_2017956_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 367.0
CMS2_k127_2017956_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 342.0
CMS2_k127_2017956_4 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 320.0
CMS2_k127_2017956_5 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000209 275.0
CMS2_k127_2017956_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000003749 195.0
CMS2_k127_202856_0 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 467.0
CMS2_k127_202856_1 Electron transfer flavoprotein K03522 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 449.0
CMS2_k127_202856_2 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 408.0
CMS2_k127_202856_3 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 400.0
CMS2_k127_202856_4 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000002637 263.0
CMS2_k127_202856_5 Transcriptional regulator - - - 0.000000000000000000000000000000000004593 141.0
CMS2_k127_202856_6 Hypoxia induced protein conserved region - - - 0.0000000001278 65.0
CMS2_k127_202856_7 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.0003006 46.0
CMS2_k127_205083_0 Involved in the TonB-independent uptake of proteins K03641 - - 4.498e-202 654.0
CMS2_k127_205083_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000002409 216.0
CMS2_k127_205083_2 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000001479 200.0
CMS2_k127_205083_3 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000000002667 189.0
CMS2_k127_205083_4 Cell division and transport-associated protein TolA - - - 0.000000000000000000000000000000000000000001317 169.0
CMS2_k127_205083_5 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000001206 130.0
CMS2_k127_2053379_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 558.0
CMS2_k127_2053379_1 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 421.0
CMS2_k127_2053379_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 392.0
CMS2_k127_2053379_3 sugar phosphatases of the HAD superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004635 271.0
CMS2_k127_2053379_4 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000933 258.0
CMS2_k127_2053379_5 Binding-protein-dependent transport system inner membrane component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004408 244.0
CMS2_k127_2053379_6 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000007453 237.0
CMS2_k127_2053379_7 SpoU rRNA Methylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001355 235.0
CMS2_k127_2053379_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000949 209.0
CMS2_k127_2053379_9 invasion associated locus B - - - 0.0000000000000000000000000000000000000000003448 181.0
CMS2_k127_2054707_0 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001913 267.0
CMS2_k127_2054707_1 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000004773 214.0
CMS2_k127_2054707_2 signal transduction histidine kinase K13587 - 2.7.13.3 0.0000000000000000004752 96.0
CMS2_k127_2054707_3 histidine kinase A domain protein domain protein - - - 0.0000868 53.0
CMS2_k127_2068783_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 1.127e-227 712.0
CMS2_k127_2068783_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 484.0
CMS2_k127_2068783_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 424.0
CMS2_k127_2068783_3 Alpha/beta hydrolase family K07020 - - 0.00000000000000000000000000000000000000000000000000000000000000000002542 238.0
CMS2_k127_2068783_4 Stringent starvation protein B K09985 - - 0.000000000000000000000000000000000000000000000000005995 188.0
CMS2_k127_2068783_5 protein involved in outer membrane biogenesis K07289 - - 0.000000000000000000000000000000000000000000000006063 195.0
CMS2_k127_2068783_6 Ribbon-helix-helix domain - - - 0.000000000000009825 78.0
CMS2_k127_2079912_0 Fad dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000008708 181.0
CMS2_k127_2079912_1 Crp-like helix-turn-helix domain K10914 - - 0.000000000000000000000000000000000000000008586 163.0
CMS2_k127_2079912_2 alpha/beta hydrolase fold - - - 0.000000000000000000000000000335 122.0
CMS2_k127_2079912_3 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000005859 103.0
CMS2_k127_2099895_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1870.0
CMS2_k127_2099895_1 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 422.0
CMS2_k127_2099895_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000000000000000000000000000449 181.0
CMS2_k127_2104342_0 Amidase K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 447.0
CMS2_k127_2104342_1 Aspartyl/Asparaginyl beta-hydroxylase K00476 - 1.14.11.16 0.0000000000000000000000000000000000000000000000000000000000000000005985 238.0
CMS2_k127_2104342_2 transcriptional regulator - - - 0.000000000000000000000000001046 121.0
CMS2_k127_2114631_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1054.0
CMS2_k127_2114631_1 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 500.0
CMS2_k127_2114631_2 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 477.0
CMS2_k127_2114631_3 CYTH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 440.0
CMS2_k127_2114631_4 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 391.0
CMS2_k127_2114631_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 353.0
CMS2_k127_2114631_6 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000211 273.0
CMS2_k127_2114631_7 COG0593 ATPase involved in DNA replication initiation - - - 0.0000000000000000000000000000000000000000000000000000000002556 220.0
CMS2_k127_2114631_8 Phosphohistidine phosphatase SixA K08296 - - 0.00000000000000000000000000000000000000000000007296 174.0
CMS2_k127_2114631_9 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000001205 131.0
CMS2_k127_2115464_0 COG1653 ABC-type sugar transport system, periplasmic component K05813 - - 1.17e-245 766.0
CMS2_k127_2115464_1 COG1175 ABC-type sugar transport systems, permease components K05814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 544.0
CMS2_k127_2115464_10 Sulfotransferase family - - - 0.000000008105 67.0
CMS2_k127_2115464_11 phosphocarrier protein hpr K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0044424,GO:0044464,GO:0051179,GO:0051234,GO:0071702 - 0.0003525 44.0
CMS2_k127_2115464_2 Belongs to the ABC transporter superfamily K05816 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015169,GO:0015399,GO:0015405,GO:0015430,GO:0015605,GO:0015711,GO:0015748,GO:0015794,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1901264,GO:1901505 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 516.0
CMS2_k127_2115464_3 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 505.0
CMS2_k127_2115464_4 Dak1 domain K00863,K05878 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0047324 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 439.0
CMS2_k127_2115464_5 PEP-utilising enzyme, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 444.0
CMS2_k127_2115464_6 - - - - 0.00000000000000000000000000000000001972 138.0
CMS2_k127_2115464_7 - - - - 0.000000000000000000000000000000203 128.0
CMS2_k127_2115464_8 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000001536 119.0
CMS2_k127_2115464_9 - - - - 0.000000003289 63.0
CMS2_k127_212307_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1105.0
CMS2_k127_212307_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 2.963e-229 716.0
CMS2_k127_212307_10 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000000000000000001916 160.0
CMS2_k127_212307_11 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000004098 110.0
CMS2_k127_212307_12 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000004331 72.0
CMS2_k127_212307_2 Aminotransferase K00812 - 2.6.1.1 2.694e-209 656.0
CMS2_k127_212307_3 ABC1 family - - - 3.964e-200 635.0
CMS2_k127_212307_4 NAD(P) transhydrogenase, alpha subunit K00324 GO:0000166,GO:0003674,GO:0003824,GO:0003957,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0008746,GO:0008750,GO:0009117,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015672,GO:0016491,GO:0016651,GO:0016652,GO:0019362,GO:0019637,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046496,GO:0046983,GO:0048037,GO:0050662,GO:0051179,GO:0051186,GO:0051234,GO:0051287,GO:0055085,GO:0055086,GO:0055114,GO:0070403,GO:0070404,GO:0071704,GO:0072524,GO:0097159,GO:0098655,GO:0098660,GO:0098662,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1902600 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 499.0
CMS2_k127_212307_5 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 499.0
CMS2_k127_212307_6 CorA-like Mg2+ transporter protein K16074 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 301.0
CMS2_k127_212307_7 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000008258 247.0
CMS2_k127_212307_8 COQ9 K18587 - - 0.000000000000000000000000000000000000000000000000000000000001258 220.0
CMS2_k127_212307_9 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000000000000007933 181.0
CMS2_k127_2138581_0 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 390.0
CMS2_k127_2138581_1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases K00019 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 359.0
CMS2_k127_2149211_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 568.0
CMS2_k127_2149211_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 301.0
CMS2_k127_2150059_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1149.0
CMS2_k127_2150059_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 7.129e-274 864.0
CMS2_k127_2150059_10 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001316 280.0
CMS2_k127_2150059_11 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005488 280.0
CMS2_k127_2150059_12 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001728 274.0
CMS2_k127_2150059_13 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005655 254.0
CMS2_k127_2150059_14 Na H antiporter K03316 - - 0.0000000000000000000000000000000000000000000000000000000000000002812 224.0
CMS2_k127_2150059_15 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000004797 122.0
CMS2_k127_2150059_16 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000001793 92.0
CMS2_k127_2150059_2 III protein, CoA-transferase family K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 587.0
CMS2_k127_2150059_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 559.0
CMS2_k127_2150059_4 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 485.0
CMS2_k127_2150059_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 444.0
CMS2_k127_2150059_6 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 436.0
CMS2_k127_2150059_7 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 412.0
CMS2_k127_2150059_8 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 384.0
CMS2_k127_2150059_9 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 301.0
CMS2_k127_2165194_0 Putative modulator of DNA gyrase K03568 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 5.953e-217 679.0
CMS2_k127_2165194_1 Protein of unknown function (DUF3422) - - - 0.0000000000000000000000000000007633 124.0
CMS2_k127_2170308_0 Domain of unknown function (DUF4070) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 512.0
CMS2_k127_2170308_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002743 261.0
CMS2_k127_2170308_2 - - - - 0.000000000000000000000000000000002402 134.0
CMS2_k127_2170308_3 oxidation-reduction process - - - 0.0000000000000000000000000001415 122.0
CMS2_k127_2170308_4 - - - - 0.00003926 48.0
CMS2_k127_2178669_0 Belongs to the GcvT family K00315 - 1.5.8.4 2.123e-229 713.0
CMS2_k127_2178669_1 PFAM trimethylamine methyltransferase K14083 - 2.1.1.250 7.277e-203 645.0
CMS2_k127_2178669_2 Major Facilitator Superfamily - - - 0.00000000000018 78.0
CMS2_k127_218690_0 Pfam Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008974 564.0
CMS2_k127_218690_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 367.0
CMS2_k127_218690_2 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000006436 220.0
CMS2_k127_218690_3 Phospholipase/Carboxylesterase K06999 - - 0.000000000000893 72.0
CMS2_k127_2193615_0 Sulfate transporter K03321 - - 9.29e-241 756.0
CMS2_k127_2193615_1 ABC transporter C-terminal domain K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 379.0
CMS2_k127_2193615_2 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 370.0
CMS2_k127_2204889_0 Hydrolase CocE NonD family K06978 - - 3.739e-237 752.0
CMS2_k127_2204889_1 alpha/beta hydrolase fold K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002734 282.0
CMS2_k127_2234105_0 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000287 268.0
CMS2_k127_2234105_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003829 248.0
CMS2_k127_2234105_2 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006833 241.0
CMS2_k127_2234105_3 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000003247 233.0
CMS2_k127_2234105_4 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000391 158.0
CMS2_k127_2234105_5 Belongs to the peptidase S1C family - - - 0.00000000000000000000000000003941 122.0
CMS2_k127_2234105_6 Resolvase - - - 0.0000002819 55.0
CMS2_k127_2246101_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 590.0
CMS2_k127_2246101_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007593 320.0
CMS2_k127_2246101_2 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 295.0
CMS2_k127_2246101_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000002026 266.0
CMS2_k127_2246101_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000427 173.0
CMS2_k127_2246101_5 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 0.00000000000000000000001278 101.0
CMS2_k127_2246899_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1190.0
CMS2_k127_2257904_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.112e-292 904.0
CMS2_k127_2257904_1 C-terminal domain of 1-Cys peroxiredoxin - GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046686,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 396.0
CMS2_k127_2257904_2 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 382.0
CMS2_k127_2257904_4 Glycine cleavage T-protein C-terminal barrel domain K06980 - - 0.0005763 44.0
CMS2_k127_2275479_0 Sulfate tungstate uptake family ABC transporter, periplasmic substrate-binding protein K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 398.0
CMS2_k127_2275479_1 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 378.0
CMS2_k127_2275479_2 COG1910, Periplasmic molybdate-binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 366.0
CMS2_k127_2275479_3 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 327.0
CMS2_k127_2275479_4 Bacterial extracellular solute-binding protein K02020 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0030151,GO:0030288,GO:0030313,GO:0030973,GO:0031975,GO:0034220,GO:0042597,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043169,GO:0043225,GO:0043492,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0099133,GO:1901359 - 0.0000000000000000000000000000000000000000000000000000000000000005878 228.0
CMS2_k127_2275479_5 Haemolysin-III related K11068 - - 0.000000000000000000000000000000000000000000000000000000001163 207.0
CMS2_k127_2275479_6 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000001184 112.0
CMS2_k127_2284232_0 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 395.0
CMS2_k127_2284232_1 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.0000000000000000000000000000000000000000000000000000000003121 207.0
CMS2_k127_2284232_2 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000000003323 169.0
CMS2_k127_2284232_3 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000007242 139.0
CMS2_k127_2284232_4 ABC transporter transmembrane region K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000001394 96.0
CMS2_k127_2284517_0 dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 351.0
CMS2_k127_2284517_1 Transcriptional regulator K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 328.0
CMS2_k127_2284517_2 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases K18335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 319.0
CMS2_k127_2284517_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 299.0
CMS2_k127_2284517_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K08319 - 1.1.1.411 0.0000000000000000000000000000000000000000000000000001242 192.0
CMS2_k127_2284517_5 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases - - - 0.00000000000000000000000000000000000000000000000001663 184.0
CMS2_k127_2284517_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000005414 96.0
CMS2_k127_2296573_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.186e-320 989.0
CMS2_k127_2296573_1 Nucleotidyltransferase - - - 0.000000000000000000000007932 107.0
CMS2_k127_2296573_2 - - - - 0.00000000000001733 78.0
CMS2_k127_2296573_3 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000000001827 63.0
CMS2_k127_2306965_0 Berberine and berberine like - - - 8.031e-221 695.0
CMS2_k127_2306965_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 382.0
CMS2_k127_2306965_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 291.0
CMS2_k127_2306965_3 Phytanoyl-CoA dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005196 287.0
CMS2_k127_2306965_4 COG1960 Acyl-CoA dehydrogenases K19966 - 3.13.1.4 0.000000000000000000001581 94.0
CMS2_k127_2316986_0 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 453.0
CMS2_k127_2316986_1 WD domain, G-beta repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009157 364.0
CMS2_k127_2316986_2 ankyrin repeat K21437 GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0006621,GO:0008104,GO:0008150,GO:0009889,GO:0009987,GO:0010556,GO:0010869,GO:0010941,GO:0012505,GO:0019222,GO:0031323,GO:0032507,GO:0033036,GO:0033365,GO:0034613,GO:0035437,GO:0042981,GO:0043067,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045185,GO:0048471,GO:0050789,GO:0050794,GO:0051179,GO:0051235,GO:0051641,GO:0051651,GO:0060255,GO:0065007,GO:0065008,GO:0070727,GO:0070972,GO:0072595,GO:2000209 - 0.00004733 48.0
CMS2_k127_2320000_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 2.368e-295 925.0
CMS2_k127_2320000_1 COG1218 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 313.0
CMS2_k127_2320000_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06952 - - 0.00000000000000000000000000000000000000000000000000000000000000000002219 243.0
CMS2_k127_2320000_3 Squalene/phytoene synthase K21678,K21679 - 2.5.1.103,4.2.3.156 0.000000000000000000000000000000000000000000000000000000000000004522 222.0
CMS2_k127_2321738_0 Fumarate hydratase (Fumerase) K01676 GO:0003674,GO:0003824,GO:0004333,GO:0005488,GO:0005515,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016862,GO:0016999,GO:0017144,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0048037,GO:0050163,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 5.224e-243 762.0
CMS2_k127_2321738_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000486 618.0
CMS2_k127_2321738_2 transport system, permease component K05778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 593.0
CMS2_k127_2321738_3 transport system periplasmic component K05777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 535.0
CMS2_k127_2321738_4 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 388.0
CMS2_k127_2321738_5 Uncharacterised MFS-type transporter YbfB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 368.0
CMS2_k127_2321738_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 306.0
CMS2_k127_2321738_7 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000001574 121.0
CMS2_k127_2321738_8 Staphylococcal nuclease homologue - - - 0.00000000000000004562 88.0
CMS2_k127_2321738_9 S-layer homology domain - - - 0.00000000004813 74.0
CMS2_k127_2323761_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007329 555.0
CMS2_k127_2323761_1 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 426.0
CMS2_k127_2323761_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000001834 116.0
CMS2_k127_2323761_11 Sporulation related domain - - - 0.00000000000000000005136 94.0
CMS2_k127_2323761_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 365.0
CMS2_k127_2323761_3 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 362.0
CMS2_k127_2323761_4 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 338.0
CMS2_k127_2323761_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 301.0
CMS2_k127_2323761_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 287.0
CMS2_k127_2323761_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002021 269.0
CMS2_k127_2323761_8 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000174 127.0
CMS2_k127_2323761_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000000001147 114.0
CMS2_k127_2350950_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 581.0
CMS2_k127_2350950_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 522.0
CMS2_k127_2350950_2 Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 391.0
CMS2_k127_2350950_3 AFG1 family ATPase K06916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0006091,GO:0006119,GO:0006123,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007005,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0017144,GO:0019538,GO:0019637,GO:0019646,GO:0019693,GO:0022900,GO:0022904,GO:0030163,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0035694,GO:0042773,GO:0042775,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0071840,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000001683 182.0
CMS2_k127_2350950_4 GtrA-like protein - - - 0.0000000000002508 81.0
CMS2_k127_2362339_0 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 436.0
CMS2_k127_2362339_1 catalyzes the oxidation of dihydrolipoamide to lipoamide K00382 GO:0000166,GO:0003674,GO:0003824,GO:0004148,GO:0005488,GO:0005507,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005747,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009507,GO:0009536,GO:0010035,GO:0010038,GO:0016020,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0017076,GO:0019866,GO:0030554,GO:0030964,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045271,GO:0046686,GO:0046872,GO:0046914,GO:0048046,GO:0050896,GO:0050897,GO:0055114,GO:0070469,GO:0097159,GO:0097367,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.8.1.4 0.0000000000000000000000000000000009934 131.0
CMS2_k127_2362339_2 - - - - 0.000000000000003716 78.0
CMS2_k127_2367681_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 419.0
CMS2_k127_2367681_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 413.0
CMS2_k127_2367681_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 368.0
CMS2_k127_2367681_3 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 323.0
CMS2_k127_237894_0 ABC transporter K02056 - 3.6.3.17 2.332e-196 625.0
CMS2_k127_237894_1 ABC-type transport system, periplasmic component surface lipoprotein K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 549.0
CMS2_k127_237894_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 479.0
CMS2_k127_237894_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007801 408.0
CMS2_k127_237894_4 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000003095 240.0
CMS2_k127_237894_5 COG0665 Glycine D-amino acid oxidases (deaminating) K00315 - 1.5.8.4 0.0000000000000000000000000000000000000000000000000000000000000004587 222.0
CMS2_k127_238120_0 Aerotolerance regulator N-terminal - - - 2.992e-282 895.0
CMS2_k127_238120_1 glutamate--cysteine ligase K01919 - 6.3.2.2 3.701e-224 701.0
CMS2_k127_238120_10 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002748 246.0
CMS2_k127_238120_11 Protein of unknown function (DUF1285) K09986 - - 0.000000000000000000000000000000000000000000000000000002994 215.0
CMS2_k127_238120_12 Thiol disulfide interchange protein K04084,K08344 - 1.8.1.8 0.00000000000000000000000000000000000003398 146.0
CMS2_k127_238120_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 494.0
CMS2_k127_238120_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 480.0
CMS2_k127_238120_4 poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 410.0
CMS2_k127_238120_5 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 357.0
CMS2_k127_238120_6 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 310.0
CMS2_k127_238120_7 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008532 317.0
CMS2_k127_238120_8 Ribosomal protein L11 methyltransferase (PrmA) - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010565,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018023,GO:0018193,GO:0018205,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031974,GO:0031998,GO:0031999,GO:0032259,GO:0036211,GO:0043086,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0043467,GO:0044092,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045833,GO:0045922,GO:0046320,GO:0046322,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050994,GO:0050995,GO:0051341,GO:0051354,GO:0062012,GO:0062014,GO:0065007,GO:0065009,GO:0070013,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1904732,GO:1904733,GO:1904735,GO:1904736 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002673 274.0
CMS2_k127_238120_9 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008306 259.0
CMS2_k127_2383909_0 COG1520 FOG WD40-like repeat K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 360.0
CMS2_k127_2383909_1 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000003801 151.0
CMS2_k127_2383909_2 Protein of unknown function (DUF2794) - - - 0.00000000000000000000003534 103.0
CMS2_k127_2385197_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 1.257e-286 895.0
CMS2_k127_2385197_1 Branched-chain amino acid transport system / permease component K11960 - - 7.563e-194 619.0
CMS2_k127_2385197_10 carboxylic acid catabolic process - - - 0.000000000000000000000000000000000000000000000003527 177.0
CMS2_k127_2385197_11 in Brucella suis the urease encoded by this operon (one of two urease-encoding operons found in its genome) is involved with urease activity, optimum growth, resistance to low-pH killing in-vitro and persistence in-vivo, while the other operon does not seem to be active K01429 GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009039,GO:0016787,GO:0016810,GO:0016811 3.5.1.5 0.000000000000000000000000000000000000000001818 162.0
CMS2_k127_2385197_2 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 559.0
CMS2_k127_2385197_3 ATPases associated with a variety of cellular activities K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 366.0
CMS2_k127_2385197_4 abc transporter atp-binding protein K11962 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 364.0
CMS2_k127_2385197_5 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 338.0
CMS2_k127_2385197_6 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.000000000000000000000000000000000000000000000000000000000000000000001142 250.0
CMS2_k127_2385197_7 UreF K03188 - - 0.00000000000000000000000000000000000000000000000000000000000000001173 233.0
CMS2_k127_2385197_8 Belongs to the urease gamma subunit family K01430,K14048 - 3.5.1.5 0.000000000000000000000000000000000000000000000000007656 181.0
CMS2_k127_2385197_9 UreE urease accessory protein, N-terminal domain K03187 - - 0.0000000000000000000000000000000000000000000000005453 183.0
CMS2_k127_2396910_0 dioxygenase K00471 - 1.14.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 526.0
CMS2_k127_2396910_1 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.00000000000000000000000000000000000000000000000000000000001321 214.0
CMS2_k127_2400930_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K00317 - 1.5.8.1,1.5.8.2 4.655e-281 879.0
CMS2_k127_2400930_1 protein conserved in bacteria K07793 - - 3.107e-267 829.0
CMS2_k127_2400930_2 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 607.0
CMS2_k127_2400930_3 Tripartite tricarboxylate transporter family receptor K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 524.0
CMS2_k127_2400930_4 BetI-type transcriptional repressor, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000004909 225.0
CMS2_k127_2400930_5 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000000000000000000000000000000000000000000000385 194.0
CMS2_k127_2400930_6 LysE type translocator - - - 0.000000000000000000000000000000003427 130.0
CMS2_k127_241598_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.809e-234 732.0
CMS2_k127_241598_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.068e-231 724.0
CMS2_k127_2432037_0 Belongs to the GcvT family - - - 1.705e-270 839.0
CMS2_k127_2432037_1 Amidohydrolase family K05603 - 3.5.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 508.0
CMS2_k127_2433357_0 Creatinase/Prolidase N-terminal domain K01271,K15783 - 3.4.13.9,3.5.4.44 8.768e-211 659.0
CMS2_k127_2433357_1 Succinylglutamate desuccinylase / Aspartoacylase family K15784 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.1.125 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 487.0
CMS2_k127_2433357_10 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000012 125.0
CMS2_k127_2433357_11 Protein conserved in bacteria - - - 0.000003476 55.0
CMS2_k127_2433357_2 ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 441.0
CMS2_k127_2433357_3 Ectoine utilization K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 432.0
CMS2_k127_2433357_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 419.0
CMS2_k127_2433357_5 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 402.0
CMS2_k127_2433357_6 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 327.0
CMS2_k127_2433357_7 - K07112 - - 0.000000000000000000000000000000000000000000004266 174.0
CMS2_k127_2433357_8 transporter component K07112 - - 0.0000000000000000000000000000000000000000003533 162.0
CMS2_k127_2433357_9 SapC - - - 0.000000000000000000000000000000000000000007492 168.0
CMS2_k127_2438_0 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000001552 221.0
CMS2_k127_2438_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000004613 228.0
CMS2_k127_2448421_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0 1058.0
CMS2_k127_2448421_1 Tellurite resistance protein TerB K05801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 344.0
CMS2_k127_2448421_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily K15268 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 302.0
CMS2_k127_2448421_3 COG3023 Negative regulator of beta-lactamase expression K01447 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000009966 272.0
CMS2_k127_2448421_4 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000001045 167.0
CMS2_k127_2448421_5 TIGRFAM ATP-dependent DNA helicase, RecQ K03654 - 3.6.4.12 0.00000000000000262 78.0
CMS2_k127_2479325_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.59e-223 698.0
CMS2_k127_2479325_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001224 242.0
CMS2_k127_2480810_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1692.0
CMS2_k127_2480810_1 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 606.0
CMS2_k127_2480810_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 535.0
CMS2_k127_2480810_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006266 254.0
CMS2_k127_2480810_4 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000005935 241.0
CMS2_k127_2480810_5 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000001358 190.0
CMS2_k127_2480810_6 Mitochondrial fission ELM1 K07276 - - 0.000000000000000000000001449 106.0
CMS2_k127_2485369_0 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K03430 - 2.6.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 544.0
CMS2_k127_2485369_1 Type I phosphodiesterase / nucleotide pyrophosphatase K19670 - 3.11.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 340.0
CMS2_k127_2485369_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006074 275.0
CMS2_k127_2485369_3 transcriptional regulator K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006586 272.0
CMS2_k127_2485369_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000008303 179.0
CMS2_k127_2485369_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000009225 121.0
CMS2_k127_2485369_6 PFAM Rhomboid family protein - - - 0.0000000000000000000001134 106.0
CMS2_k127_2485369_7 signal transduction histidine kinase K13587 - 2.7.13.3 0.0000000000000000005327 95.0
CMS2_k127_2492041_0 ABC-type oligopeptide transport system periplasmic component K02035,K15580 - - 8.536e-265 823.0
CMS2_k127_2492041_1 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032,K10823,K13896,K15583 - - 4.416e-230 723.0
CMS2_k127_2492041_2 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 547.0
CMS2_k127_2492041_3 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K15582 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 502.0
CMS2_k127_2492041_4 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007823 467.0
CMS2_k127_2492041_5 COG0665 Glycine D-amino acid oxidases (deaminating) K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 437.0
CMS2_k127_2492041_6 racemase activity, acting on amino acids and derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000346 265.0
CMS2_k127_2492041_7 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000001135 56.0
CMS2_k127_249962_0 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 456.0
CMS2_k127_249962_1 COG0685 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009313 449.0
CMS2_k127_249962_2 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000000000827 189.0
CMS2_k127_249962_3 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000003785 142.0
CMS2_k127_249962_4 Virulence factor - - - 0.000000000000000000000000000000005865 135.0
CMS2_k127_2511230_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.548e-290 910.0
CMS2_k127_2511230_1 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000001227 132.0
CMS2_k127_2511230_2 Transition state regulatory protein AbrB K07120 - - 0.0000000000000000000000000001447 119.0
CMS2_k127_2511230_3 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.00000000000000001139 87.0
CMS2_k127_2516418_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 546.0
CMS2_k127_2516418_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 552.0
CMS2_k127_2516418_2 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K00375 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 533.0
CMS2_k127_2516418_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 431.0
CMS2_k127_2516418_4 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006513 430.0
CMS2_k127_2516418_5 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 337.0
CMS2_k127_2516418_6 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009776 262.0
CMS2_k127_2516418_7 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000000000000002833 150.0
CMS2_k127_2516418_8 Putative transmembrane protein (Alph_Pro_TM) - - - 0.0000000000000000000000000000000006729 143.0
CMS2_k127_2516418_9 Protein of unknown function (DUF1674) - - - 0.000000000003756 71.0
CMS2_k127_2516933_0 Diaminopropionate ammonia-lyase K01751 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008838,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575 4.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 411.0
CMS2_k127_2516933_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000011 107.0
CMS2_k127_2516933_2 Condensation domain - - - 0.00000000001584 69.0
CMS2_k127_2541470_0 Flavoprotein involved in K transport K07222 - - 1.323e-205 645.0
CMS2_k127_2541470_1 Aldehyde dehydrogenase family K13877 - 1.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 354.0
CMS2_k127_254280_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 475.0
CMS2_k127_254280_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000005561 78.0
CMS2_k127_254280_2 Lipid A Biosynthesis N-terminal domain - - - 0.000000000002906 70.0
CMS2_k127_2546981_0 COG2217 Cation transport ATPase K17686 - 3.6.3.54 0.0 1200.0
CMS2_k127_2546981_1 transcriptional K19591 - - 0.000000000000000000000000000000000000000000000001952 184.0
CMS2_k127_2546981_2 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000001745 170.0
CMS2_k127_2546981_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000225 139.0
CMS2_k127_2546981_4 - - - - 0.0000000000000000000004188 102.0
CMS2_k127_2546981_5 Short C-terminal domain - - - 0.000000000189 70.0
CMS2_k127_2546981_6 hydroperoxide reductase activity K07486 - - 0.00007875 48.0
CMS2_k127_2568328_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 607.0
CMS2_k127_2568328_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000009672 221.0
CMS2_k127_2568328_2 oxidation-reduction process - - - 0.0000000000000000000000000000000000000008595 152.0
CMS2_k127_2578024_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 312.0
CMS2_k127_2578024_1 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000000000000000007031 202.0
CMS2_k127_2578024_2 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000000000001554 143.0
CMS2_k127_2578024_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000003982 126.0
CMS2_k127_2592540_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000756 522.0
CMS2_k127_2592540_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 483.0
CMS2_k127_2592540_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 404.0
CMS2_k127_2592540_3 COG1961 Site-specific recombinases, DNA invertase Pin homologs K06400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 370.0
CMS2_k127_2592540_4 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000004808 164.0
CMS2_k127_2592540_5 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000003487 132.0
CMS2_k127_2592540_6 receptor - - - 0.000001322 53.0
CMS2_k127_2621957_0 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 325.0
CMS2_k127_2621957_1 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000009984 123.0
CMS2_k127_2621957_2 Pyridoxal-phosphate dependent enzyme K01754 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006520,GO:0006563,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0016853,GO:0016854,GO:0016855,GO:0017144,GO:0018249,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0030378,GO:0030848,GO:0036094,GO:0036211,GO:0036361,GO:0042219,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046416,GO:0046437,GO:0046872,GO:0047661,GO:0048037,GO:0050662,GO:0070178,GO:0070179,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 0.00000000009947 63.0
CMS2_k127_2623047_0 transport system, ATPase component K05779 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 298.0
CMS2_k127_2623047_1 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins - - - 0.0000000000000000000000000000000000000000000000000000000000006346 219.0
CMS2_k127_2623047_2 protein affecting Mg2 Co2 transport K06195 - - 0.000000000000000000000000000000000000000000000000000001364 194.0
CMS2_k127_2623047_3 PFAM OsmC family protein - - - 0.0000000000000000000000000000000000000000000000000001092 191.0
CMS2_k127_2623047_4 cobalamin synthesis protein - - - 0.0000000000000000000000000000000000004086 141.0
CMS2_k127_2623047_5 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000008906 91.0
CMS2_k127_2651981_0 aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 351.0
CMS2_k127_2651981_1 Amidohydrolase - - - 0.000000000000000000000000000000001964 130.0
CMS2_k127_2658843_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 8.977e-302 932.0
CMS2_k127_268060_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 504.0
CMS2_k127_268060_1 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005034 249.0
CMS2_k127_268060_2 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000005388 108.0
CMS2_k127_2689576_0 Pyridoxal-phosphate dependent enzyme K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 550.0
CMS2_k127_2689576_1 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006415 306.0
CMS2_k127_2689576_2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000572 216.0
CMS2_k127_2689576_3 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000003029 156.0
CMS2_k127_2689576_4 OsmC-like protein K06889,K07397 - - 0.000000000007652 66.0
CMS2_k127_2706686_0 FAD dependent oxidoreductase K03153 - 1.4.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 460.0
CMS2_k127_2706686_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 381.0
CMS2_k127_2706686_2 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 310.0
CMS2_k127_2706686_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000006542 214.0
CMS2_k127_2706686_4 Thiamine monophosphate synthase - - - 0.000000000000000000000000000000000000165 149.0
CMS2_k127_2706686_5 thiamine biosynthesis protein ThiS K03154 - - 0.0000000001216 64.0
CMS2_k127_2711191_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 345.0
CMS2_k127_2711191_1 - - - - 0.00000000000000000000000000000000000000000000000004263 194.0
CMS2_k127_2716457_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 353.0
CMS2_k127_2716457_1 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000002485 165.0
CMS2_k127_2716457_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000001268 138.0
CMS2_k127_2717830_0 elongator protein 3 miab nifb - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 541.0
CMS2_k127_2717830_1 ATPase with chaperone activity K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 479.0
CMS2_k127_2717830_2 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005583 252.0
CMS2_k127_2717830_3 elongator protein 3 miab nifb - - - 0.0000000000000000000000000000000000000000000000000000000000005623 216.0
CMS2_k127_2717830_4 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000007701 221.0
CMS2_k127_2717830_5 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000000000000000001052 196.0
CMS2_k127_2720875_0 COG2873 O-acetylhomoserine sulfhydrylase K01738,K01740 - 2.5.1.47,2.5.1.49 8.198e-208 664.0
CMS2_k127_2720875_1 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 358.0
CMS2_k127_2720875_2 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000002477 227.0
CMS2_k127_2720875_3 Major Facilitator Superfamily - - - 0.0000000000000000005667 91.0
CMS2_k127_2720875_4 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000004662 70.0
CMS2_k127_2727185_0 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 399.0
CMS2_k127_2727185_1 deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 359.0
CMS2_k127_2727185_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000006979 199.0
CMS2_k127_2727185_3 Belongs to the HesB IscA family K13628,K15724 - - 0.00000000000000000000000000000000000000000009265 163.0
CMS2_k127_2728535_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 575.0
CMS2_k127_2728535_1 Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 575.0
CMS2_k127_2728535_10 Transcriptional regulator PadR-like family - - - 0.00000000000000000000000000000000000000000000003962 175.0
CMS2_k127_2728535_11 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000607 160.0
CMS2_k127_2728535_2 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 536.0
CMS2_k127_2728535_3 extracellular solute-binding protein, family 7 K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 428.0
CMS2_k127_2728535_4 Belongs to the PdxA family K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 398.0
CMS2_k127_2728535_5 COG1012 NAD-dependent aldehyde dehydrogenases K13877 - 1.2.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 319.0
CMS2_k127_2728535_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001705 284.0
CMS2_k127_2728535_7 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007222 266.0
CMS2_k127_2728535_8 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18989 - - 0.00000000000000000000000000000000000000000000000000000000000000000003543 234.0
CMS2_k127_2728535_9 Bacterial signalling protein N terminal repeat - - - 0.0000000000000000000000000000000000000000000000000009103 196.0
CMS2_k127_2749363_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.565e-199 631.0
CMS2_k127_2749363_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 362.0
CMS2_k127_2749363_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 343.0
CMS2_k127_2749363_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 293.0
CMS2_k127_2749363_4 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 289.0
CMS2_k127_2749363_5 Acetyltransferase (GNAT) family K03829 - - 0.000000000000000000000000000000000000006426 152.0
CMS2_k127_2749363_6 Aminotransferase class I and II - - - 0.000000003673 57.0
CMS2_k127_2750665_0 PFAM SMC domain protein K03546 - - 0.000000000000000000000000000000000000000000000000002349 201.0
CMS2_k127_2760790_0 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 360.0
CMS2_k127_2760790_1 UPF0126 domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002813 275.0
CMS2_k127_2760790_2 TRAP transporter solute receptor TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002242 272.0
CMS2_k127_2760790_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000002743 216.0
CMS2_k127_2760790_4 EamA-like transporter family K15270 - - 0.00000000000000000000000000000000000000000004625 165.0
CMS2_k127_2760790_5 Staphylococcal nuclease homologue - - - 0.00000000000000003236 88.0
CMS2_k127_2764038_0 GTP-binding protein TypA K06207 - - 2.076e-284 884.0
CMS2_k127_2764038_1 COG0524 Sugar kinases, ribokinase family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 446.0
CMS2_k127_2764038_2 Major facilitator superfamily K08218 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015835,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000006819 211.0
CMS2_k127_2764038_3 Etoposide-induced protein 2.4 (EI24) - - - 0.000000000000000000000000000000000000000000000000001128 193.0
CMS2_k127_2764038_4 Polymer-forming cytoskeletal - - - 0.000000000000000000000005575 110.0
CMS2_k127_2764038_5 - - - - 0.000000000000382 77.0
CMS2_k127_2783003_0 4Fe-4S dicluster domain - - - 2.367e-256 809.0
CMS2_k127_2783003_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 559.0
CMS2_k127_2783003_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000008616 260.0
CMS2_k127_2783003_11 - - - - 0.000000000000000000000000000002384 132.0
CMS2_k127_2783003_12 Cytochrome c - - - 0.00000000000000000000288 97.0
CMS2_k127_2783003_13 - - - - 0.000000002665 65.0
CMS2_k127_2783003_14 Domain of unknown function (DUF1127) - - - 0.00000004023 57.0
CMS2_k127_2783003_2 RimK-like ATPgrasp N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004764 556.0
CMS2_k127_2783003_3 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 486.0
CMS2_k127_2783003_4 Required for the activity of the bacterial periplasmic transport system of putrescine K11069,K11073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 411.0
CMS2_k127_2783003_5 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 370.0
CMS2_k127_2783003_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 344.0
CMS2_k127_2783003_7 Transcriptional regulator K03566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006573 336.0
CMS2_k127_2783003_8 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001112 269.0
CMS2_k127_2783003_9 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 265.0
CMS2_k127_2794430_0 Tripartite tricarboxylate transporter TctA family K07793 - - 6.281e-221 694.0
CMS2_k127_2794430_1 L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007203 572.0
CMS2_k127_2794430_2 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 552.0
CMS2_k127_2794430_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 291.0
CMS2_k127_2794430_4 Enoyl-CoA hydratase carnithine racemase K01692,K11264 - 4.1.1.41,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000008714 230.0
CMS2_k127_2794430_5 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000005597 218.0
CMS2_k127_2794430_6 Tripartite tricarboxylate transporter TctB family - - - 0.000000000764 66.0
CMS2_k127_2801479_0 D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 338.0
CMS2_k127_2801479_1 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000005166 154.0
CMS2_k127_2801479_2 Belongs to the ABC transporter superfamily K13896 - - 0.0000000000000000000000000000000000000006014 149.0
CMS2_k127_2805649_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1011.0
CMS2_k127_2805649_1 Belongs to the GcvT family K17486 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0016740,GO:0016741,GO:0032259 2.1.1.269 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 587.0
CMS2_k127_2805649_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001,K19745 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 308.0
CMS2_k127_2805649_3 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002117 264.0
CMS2_k127_2805649_4 - - - - 0.00002368 54.0
CMS2_k127_2811616_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.314e-224 703.0
CMS2_k127_2811616_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000006302 271.0
CMS2_k127_2820494_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 553.0
CMS2_k127_2820494_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 475.0
CMS2_k127_2820494_2 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008726 253.0
CMS2_k127_2820494_3 COG4942 Membrane-bound metallopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001859 250.0
CMS2_k127_2820494_4 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000002271 229.0
CMS2_k127_2823540_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 404.0
CMS2_k127_2823540_1 PFAM Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 288.0
CMS2_k127_2823540_2 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001175 273.0
CMS2_k127_2823922_0 DNA polymerase K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 547.0
CMS2_k127_2823922_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 405.0
CMS2_k127_2823922_2 DNA polymerase K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 396.0
CMS2_k127_2823922_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 387.0
CMS2_k127_2823922_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 370.0
CMS2_k127_2823922_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008069 319.0
CMS2_k127_2823922_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008651 269.0
CMS2_k127_2826756_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 475.0
CMS2_k127_2826756_1 membrane K08973 - - 0.00000000000000000000000000000000000000000000000000003222 190.0
CMS2_k127_2826756_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000006061 59.0
CMS2_k127_2830077_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 439.0
CMS2_k127_2830077_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009579 296.0
CMS2_k127_2830077_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000001803 141.0
CMS2_k127_2830077_3 - - - - 0.000000004248 68.0
CMS2_k127_283223_0 sarcosine oxidase, beta subunit K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 608.0
CMS2_k127_283223_1 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 422.0
CMS2_k127_283223_2 Belongs to the GcvT family K00302,K22086 - 1.5.3.1,1.5.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 404.0
CMS2_k127_283223_3 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006816 305.0
CMS2_k127_283223_4 Helix-turn-helix domain, rpiR family - - - 0.000000000000000000000000000000000000000000007138 174.0
CMS2_k127_283223_5 Sarcosine oxidase delta subunit K00304 - 1.5.3.1 0.000000000000000002046 87.0
CMS2_k127_283223_6 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.00000000000004751 74.0
CMS2_k127_283223_7 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.000004761 53.0
CMS2_k127_2832858_0 COG4166 ABC-type oligopeptide transport system, periplasmic component K13893 - - 1.165e-267 852.0
CMS2_k127_2832858_1 Belongs to the ABC transporter superfamily K13896 - - 2.851e-219 705.0
CMS2_k127_2832858_2 transport system, permease component K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 583.0
CMS2_k127_2832858_3 transport system, permease component K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 548.0
CMS2_k127_2832858_4 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.000000000000000000000000000000000000000000000000000000000000000000004289 244.0
CMS2_k127_2832858_5 cytochrome K08738 - - 0.00000000004718 70.0
CMS2_k127_2840685_0 Thiolase, N-terminal domain K00626,K00632,K07823 - 2.3.1.16,2.3.1.174,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 433.0
CMS2_k127_2840685_1 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 418.0
CMS2_k127_2840685_2 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000002404 246.0
CMS2_k127_2848387_0 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 479.0
CMS2_k127_2848387_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 475.0
CMS2_k127_2848387_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001426 257.0
CMS2_k127_2848387_3 COG1960 Acyl-CoA dehydrogenases K20035 - - 0.0000000000000000000000000000000000000000000000000000004044 199.0
CMS2_k127_2852048_0 PKHD-type hydroxylase K07336 - - 0.000000000000000000000000000000000000000000000000000000000002137 217.0
CMS2_k127_2852048_1 17 kDa outer membrane surface antigen - - - 0.00000000000001908 79.0
CMS2_k127_2853084_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 2.855e-275 868.0
CMS2_k127_2853084_1 Polysaccharide biosynthesis protein - - - 5.616e-194 624.0
CMS2_k127_2853084_2 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 571.0
CMS2_k127_2853084_3 sulfate adenylyltransferase subunit 2 K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 494.0
CMS2_k127_2853084_4 epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 437.0
CMS2_k127_2853084_5 Reductase C-terminal K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 387.0
CMS2_k127_2853084_6 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.0000000000000000000000000000000005625 136.0
CMS2_k127_2853084_7 Acetyltransferase (GNAT) family - - - 0.000000000005627 69.0
CMS2_k127_2853084_8 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.000004785 48.0
CMS2_k127_2862413_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 3.815e-293 908.0
CMS2_k127_2862413_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 602.0
CMS2_k127_2862413_2 Putative beta-barrel porin 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 567.0
CMS2_k127_2862413_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 317.0
CMS2_k127_2862413_4 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000008359 258.0
CMS2_k127_2862413_5 Acetolactate synthase small K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000017 244.0
CMS2_k127_2862413_6 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000007142 76.0
CMS2_k127_2867737_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 419.0
CMS2_k127_2867737_1 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004215 271.0
CMS2_k127_2867737_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000004617 247.0
CMS2_k127_2867737_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000008615 86.0
CMS2_k127_2867737_5 Ca2 -binding protein (EF-Hand superfamily - - - 0.0000000125 61.0
CMS2_k127_2895114_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1241.0
CMS2_k127_2895114_1 Peptidogalycan biosysnthesis/recognition K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004077 481.0
CMS2_k127_2895114_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000000002579 186.0
CMS2_k127_2895114_3 Phasin protein - - - 0.00000000000000000000000000000000000000000000000001423 188.0
CMS2_k127_2895114_4 Belongs to the peptidase S11 family K01286 - 3.4.16.4 0.000000000000000000000000000000000001808 143.0
CMS2_k127_289817_0 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 614.0
CMS2_k127_289817_1 Belongs to the mandelate racemase muconate lactonizing enzyme family K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 419.0
CMS2_k127_289817_2 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000003336 207.0
CMS2_k127_289817_3 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000002809 195.0
CMS2_k127_2900700_0 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 523.0
CMS2_k127_2900700_1 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000002621 168.0
CMS2_k127_2900700_2 Universal stress protein - - - 0.00000000000000000000000000000000000000003323 156.0
CMS2_k127_2903652_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000111 265.0
CMS2_k127_2903652_1 Chaperone SurA K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000001906 272.0
CMS2_k127_2903652_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000001368 147.0
CMS2_k127_2904469_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 6.917e-262 823.0
CMS2_k127_2904469_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 442.0
CMS2_k127_2904469_2 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 299.0
CMS2_k127_2904469_3 Glycosyl Transferase - - - 0.00000000000000000000000000000000000000000000000000000000000002092 223.0
CMS2_k127_2904469_4 - - - - 0.00000000000000000000007562 106.0
CMS2_k127_2904469_5 Phosphoglycerate mutase family - - - 0.00000000000008889 72.0
CMS2_k127_2916873_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 437.0
CMS2_k127_2916873_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006123 297.0
CMS2_k127_2919296_0 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 6.205e-295 915.0
CMS2_k127_2919296_1 Aminotransferase K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 1.69e-198 625.0
CMS2_k127_2919296_10 OmpA family - - - 0.0001629 52.0
CMS2_k127_2919296_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 548.0
CMS2_k127_2919296_3 fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 345.0
CMS2_k127_2919296_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009762 265.0
CMS2_k127_2919296_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003059 244.0
CMS2_k127_2919296_6 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006993 245.0
CMS2_k127_2919296_7 COG1494 Fructose-1,6-bisphosphatase sedoheptulose 1,7-bisphosphatase and related proteins K11532 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000005036 188.0
CMS2_k127_2919296_8 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000003781 178.0
CMS2_k127_2919296_9 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000001072 134.0
CMS2_k127_2921211_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 465.0
CMS2_k127_2921211_1 Protein of unknown function (DUF4011) - - - 0.0000002207 65.0
CMS2_k127_292188_0 Histidine kinase K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008562 480.0
CMS2_k127_292188_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 284.0
CMS2_k127_292188_2 Phenazine biosynthesis protein PhzF K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000001287 241.0
CMS2_k127_292188_3 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000005609 231.0
CMS2_k127_292188_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000007103 143.0
CMS2_k127_2930_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 295.0
CMS2_k127_2930_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000001853 233.0
CMS2_k127_2968669_0 COG1228 Imidazolonepropionase and related amidohydrolases K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 299.0
CMS2_k127_2968669_1 BioY protein K03523 - - 0.0000000000000000000000000000000000000000000000000000000000145 212.0
CMS2_k127_2968669_2 COG2188 Transcriptional regulators K05836 - - 0.00000000000000000000000000000000000000000000000000000001306 210.0
CMS2_k127_2968669_3 Cobalt transport protein K16783 - - 0.000000000000000000000000000000000000000003308 160.0
CMS2_k127_299420_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18989 - - 7.59e-279 873.0
CMS2_k127_3013962_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.126e-319 998.0
CMS2_k127_3013962_1 Participates in both transcription termination and antitermination K02600 - - 1.074e-235 739.0
CMS2_k127_3013962_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 9.985e-205 642.0
CMS2_k127_3013962_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009077 310.0
CMS2_k127_3013962_4 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000008844 258.0
CMS2_k127_3013962_5 nucleic-acid-binding protein implicated in transcription termination K07742 - - 0.0000000000000000000000000000000000000000000000000000002523 201.0
CMS2_k127_3013962_6 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000008162 197.0
CMS2_k127_3013962_7 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000005006 196.0
CMS2_k127_3013962_8 transcriptional - - - 0.0000000000000000000000000000000002769 141.0
CMS2_k127_3013962_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000002152 131.0
CMS2_k127_3030023_0 Aldehyde dehydrogenase family - - - 2.365e-205 646.0
CMS2_k127_3030023_1 Uncharacterized protein conserved in bacteria (DUF2199) - - - 0.00000000000000000000000000000000000001344 152.0
CMS2_k127_3030023_2 Imelysin K07231 - - 0.00000000000000000001342 93.0
CMS2_k127_3033364_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 355.0
CMS2_k127_3033364_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 344.0
CMS2_k127_3033364_2 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000137 296.0
CMS2_k127_3033364_3 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004851 242.0
CMS2_k127_3033364_4 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000000000000000000000000256 199.0
CMS2_k127_3033364_5 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0000000000000000000001949 100.0
CMS2_k127_3034389_0 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 374.0
CMS2_k127_3034389_1 Peptidase S24-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002854 258.0
CMS2_k127_304621_0 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 389.0
CMS2_k127_304621_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 370.0
CMS2_k127_304621_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008408,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016787,GO:0016788,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0045004,GO:0045005,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005991 310.0
CMS2_k127_304621_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 308.0
CMS2_k127_304621_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000284 246.0
CMS2_k127_304621_5 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000001834 243.0
CMS2_k127_304621_6 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000003363 194.0
CMS2_k127_304621_7 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 GO:0002790,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000005676 145.0
CMS2_k127_304621_8 FxsA cytoplasmic membrane protein K07113 - - 0.0000000000000000000000000000008669 126.0
CMS2_k127_3049939_0 AFG1-like ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008745 489.0
CMS2_k127_3049939_1 nitrite reductase [NAD(P)H] activity K15762 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 324.0
CMS2_k127_3049939_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000008534 216.0
CMS2_k127_3054081_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1273.0
CMS2_k127_3054081_1 COG2217 Cation transport ATPase K01533 - 3.6.3.4 8.401e-285 894.0
CMS2_k127_3054081_10 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000002713 165.0
CMS2_k127_3054081_11 bond formation protein, DsbB - - - 0.0000000000000000000000000000000000000000006178 163.0
CMS2_k127_3054081_12 FixH - - - 0.0000000000000000000000000000000008864 135.0
CMS2_k127_3054081_13 cytochrome oxidase maturation protein - - - 0.0000000000002219 72.0
CMS2_k127_3054081_2 Nitrogen fixation protein fixG - - - 2.169e-199 633.0
CMS2_k127_3054081_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 423.0
CMS2_k127_3054081_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 347.0
CMS2_k127_3054081_5 HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 294.0
CMS2_k127_3054081_6 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000236 251.0
CMS2_k127_3054081_7 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003966 245.0
CMS2_k127_3054081_8 COG2030 Acyl dehydratase K17865 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016043,GO:0016829,GO:0016835,GO:0016836,GO:0022607,GO:0042620,GO:0042621,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901576 4.2.1.55 0.00000000000000000000000000000000000000000000000000000000000000003056 228.0
CMS2_k127_3054081_9 ATPases associated with a variety of cellular activities K15555 - - 0.0000000000000000000000000000000000000000000000000000000000000006507 227.0
CMS2_k127_3065352_0 Homospermidine synthase K00808 - 2.5.1.44 6.975e-194 614.0
CMS2_k127_3065352_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000002073 159.0
CMS2_k127_3066380_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 575.0
CMS2_k127_3066380_1 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 377.0
CMS2_k127_3066380_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009563 369.0
CMS2_k127_3066380_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 367.0
CMS2_k127_3066380_4 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000001042 183.0
CMS2_k127_3066380_5 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.00000000002542 65.0
CMS2_k127_306770_0 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 335.0
CMS2_k127_306770_1 Malonyl-CoA decarboxylase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 304.0
CMS2_k127_3072194_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 544.0
CMS2_k127_3072194_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001804 255.0
CMS2_k127_3072194_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000004996 251.0
CMS2_k127_3072194_3 COG0314 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000275 174.0
CMS2_k127_3079877_0 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000002916 244.0
CMS2_k127_3079877_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000007514 157.0
CMS2_k127_3079877_2 Permease MlaE K02066 - - 0.00000000000000009368 86.0
CMS2_k127_3079877_3 peptidyl-tyrosine sulfation - - - 0.0008324 47.0
CMS2_k127_3081320_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 344.0
CMS2_k127_3081320_1 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001466 267.0
CMS2_k127_3081320_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000001019 165.0
CMS2_k127_3081320_3 peptidase M24 K01271 - 3.4.13.9 0.000000000000000000000000000000001412 131.0
CMS2_k127_3081320_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000002245 121.0
CMS2_k127_3093653_0 Proteasome-type protease K07395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 351.0
CMS2_k127_3093653_1 N-terminal domain of unknown function (DUF4140) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001492 269.0
CMS2_k127_3093653_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000002923 153.0
CMS2_k127_3093653_3 surface antigen - - - 0.00000000000000000000000000000000000006776 149.0
CMS2_k127_3093653_4 - - - - 0.00000000000000000000000000000004725 133.0
CMS2_k127_3093653_5 Anti-sigma-K factor rskA - - - 0.000000000000000000000000000001715 133.0
CMS2_k127_3093653_6 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000001244 111.0
CMS2_k127_3099010_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 599.0
CMS2_k127_3099010_1 ATPase with chaperone activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 428.0
CMS2_k127_3099010_2 HD phosphohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 301.0
CMS2_k127_3099010_3 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 295.0
CMS2_k127_3099010_4 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001902 276.0
CMS2_k127_3099010_5 Diguanylate cyclase - - - 0.00000000000000000000000000000000000004003 151.0
CMS2_k127_3107793_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 356.0
CMS2_k127_3107793_1 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000006366 229.0
CMS2_k127_3107793_2 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000003614 98.0
CMS2_k127_3110098_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 346.0
CMS2_k127_3110098_1 Ferredoxin, 2Fe-2S - - - 0.0000000000000000000000000000000000000000000000001347 186.0
CMS2_k127_3110098_2 COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.0000000000000000000000000000000000001554 143.0
CMS2_k127_3110098_3 domain, Protein - - - 0.00000000000000000000000000006829 124.0
CMS2_k127_3110878_0 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 480.0
CMS2_k127_3110878_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 396.0
CMS2_k127_3110878_2 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 333.0
CMS2_k127_3110878_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 317.0
CMS2_k127_3110878_4 Protein conserved in bacteria K09937 - - 0.000000003017 59.0
CMS2_k127_3113590_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.059e-319 983.0
CMS2_k127_3113590_1 MlrC C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 308.0
CMS2_k127_3113590_2 Flavin containing amine oxidoreductase K00274 - 1.4.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002608 280.0
CMS2_k127_3113590_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000002211 179.0
CMS2_k127_3115536_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1021.0
CMS2_k127_3115536_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 462.0
CMS2_k127_3115536_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 325.0
CMS2_k127_3115536_3 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000001469 264.0
CMS2_k127_3115536_4 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000000000000000000000002602 200.0
CMS2_k127_3115536_5 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000000000000000000000000000005746 185.0
CMS2_k127_3115536_6 Succinate dehydrogenase, hydrophobic anchor subunit K00242 - - 0.00000000000000000000000000000000000000006133 154.0
CMS2_k127_3115536_7 - - - - 0.0000000000000002842 82.0
CMS2_k127_3123038_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 401.0
CMS2_k127_3123038_1 Rhomboid family - - - 0.000000000000000000000000000000000000007685 150.0
CMS2_k127_3123038_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000003506 136.0
CMS2_k127_3130753_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 593.0
CMS2_k127_3130753_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 385.0
CMS2_k127_3130753_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004873 297.0
CMS2_k127_3130753_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000003596 241.0
CMS2_k127_3130753_4 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000000000000001378 147.0
CMS2_k127_3134294_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 302.0
CMS2_k127_3134294_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000001448 197.0
CMS2_k127_3134931_0 prephenate dehydrogenase K00220 - 1.3.1.12,1.3.1.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 446.0
CMS2_k127_3134931_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000294 243.0
CMS2_k127_3134931_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000009675 160.0
CMS2_k127_3134931_3 Uncharacterized protein conserved in bacteria (DUF2125) - - - 0.00000000000000000000000000002618 127.0
CMS2_k127_3147622_0 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 354.0
CMS2_k127_3147622_1 COG0530 Ca2 Na antiporter K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001166 276.0
CMS2_k127_3147622_2 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000004502 153.0
CMS2_k127_3147622_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000005771 91.0
CMS2_k127_3159165_0 Hsp70 protein K04043 - - 0.0 1011.0
CMS2_k127_3159165_1 COG0708 Exonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 374.0
CMS2_k127_3159165_2 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 340.0
CMS2_k127_3159165_3 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 304.0
CMS2_k127_3159165_4 2OG-Fe(II) oxygenase superfamily K03919 - 1.14.11.33 0.00000000000000000000000000000000000000000000000000000000000000000003016 243.0
CMS2_k127_3159165_5 DNA segregation ATPase FtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000002347 166.0
CMS2_k127_3159165_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000003709 156.0
CMS2_k127_3159165_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000005781 157.0
CMS2_k127_3165102_0 Single-stranded-DNA-specific exonuclease (RecJ) K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001115 265.0
CMS2_k127_3165102_1 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000001186 239.0
CMS2_k127_3165102_2 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000002138 99.0
CMS2_k127_3165102_3 - - - - 0.000000000000000001344 89.0
CMS2_k127_3165102_4 Polymer-forming cytoskeletal - - - 0.0000001182 59.0
CMS2_k127_3195399_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007088 567.0
CMS2_k127_3195399_1 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005396 511.0
CMS2_k127_3195399_2 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 314.0
CMS2_k127_3195399_3 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 310.0
CMS2_k127_3195399_4 Cysteine dioxygenase type I - - - 0.00000000000000000000000000000000000000000000000000000008697 199.0
CMS2_k127_3195399_5 SNARE associated Golgi protein - - - 0.00000000000000000000000001255 110.0
CMS2_k127_3195399_7 - - - - 0.00005419 53.0
CMS2_k127_3205398_0 argininosuccinate lyase K01755 - 4.3.2.1 4.295e-215 677.0
CMS2_k127_3205398_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 507.0
CMS2_k127_3205398_2 Domain of unknown function (DUF4175) - - - 0.00000000000000000000000000002056 124.0
CMS2_k127_3205398_3 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000001001 114.0
CMS2_k127_3213131_0 integral membrane protein - - - 0.00000000000001148 86.0
CMS2_k127_3213131_1 NMT1-like family K15598 - - 0.000000002142 59.0
CMS2_k127_3233291_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1047.0
CMS2_k127_3233291_1 Cysteine-rich domain - - - 8.011e-221 692.0
CMS2_k127_3233291_2 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 1.522e-202 638.0
CMS2_k127_3233291_3 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 389.0
CMS2_k127_3233291_4 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 288.0
CMS2_k127_3233291_5 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001062 260.0
CMS2_k127_3233291_6 Belongs to the Fur family K09826 - - 0.000000000000000000000000000000000000000000000000000001566 194.0
CMS2_k127_3233291_7 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000002643 190.0
CMS2_k127_3233291_8 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000004014 142.0
CMS2_k127_323496_0 ABC transporter K06158 - - 1.289e-220 698.0
CMS2_k127_323496_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 484.0
CMS2_k127_323496_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 284.0
CMS2_k127_323496_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000002265 248.0
CMS2_k127_323496_4 Uncharacterized protein conserved in bacteria (DUF2066) - - - 0.0000000000000000000000000000000000000517 153.0
CMS2_k127_3252872_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 436.0
CMS2_k127_3252872_1 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 412.0
CMS2_k127_3252872_2 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 400.0
CMS2_k127_3252872_3 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000181 257.0
CMS2_k127_3252872_4 Required for the activity of the bacterial periplasmic transport system of putrescine - - - 0.0000000000002624 70.0
CMS2_k127_3285328_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 7.767e-273 850.0
CMS2_k127_3285328_1 Amidinotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 307.0
CMS2_k127_3285328_2 Thioredoxin-like - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000002452 144.0
CMS2_k127_3286303_0 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 0.0 1431.0
CMS2_k127_3286303_1 PFAM conserved K02069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 332.0
CMS2_k127_3286303_2 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000001784 200.0
CMS2_k127_3286303_3 Autotransporter beta-domain - - - 0.0000000000000000000000000000000000000000000182 167.0
CMS2_k127_3301369_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.88e-321 994.0
CMS2_k127_3311106_0 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000000000000000000000001099 211.0
CMS2_k127_3311106_1 Protein of unknown function (DUF1194) - - - 0.0000000000000000000000000000000000000000000000000000000006802 210.0
CMS2_k127_3311106_2 luxR family - - - 0.000000000000000000000000000103 130.0
CMS2_k127_3314259_0 benzoate-CoA ligase K04105 - 6.2.1.25,6.2.1.27 2.4e-208 661.0
CMS2_k127_3314259_1 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain, 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000005268 251.0
CMS2_k127_3314259_2 Domain of unknown function (DUF4863) - - - 0.00000000000000000000000000000000000000000000000000000000002075 215.0
CMS2_k127_3314259_3 Enoyl-CoA hydratase/isomerase K01692,K15866 - 4.2.1.17,5.3.3.18 0.000000000000000000000000000000000000000000000002911 192.0
CMS2_k127_3322766_0 Type II secretion system (T2SS), protein F - - - 0.0000000000000000000000000000000000000000000000000000000000002798 223.0
CMS2_k127_3322766_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000001489 82.0
CMS2_k127_3322766_2 Flp pilus assembly protein TadB K12510 - - 0.00000000000004976 74.0
CMS2_k127_3322766_3 Type IV pilus biogenesis stability protein PilW - - - 0.0000002172 63.0
CMS2_k127_3322964_0 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 338.0
CMS2_k127_3322964_1 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005387 286.0
CMS2_k127_3322964_2 PFAM Phosphoglycerate mutase K15634 - 5.4.2.12 0.000000000000000000000000000000000001321 146.0
CMS2_k127_3336262_0 Binding-protein-dependent transport system inner membrane component K02001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 602.0
CMS2_k127_3336262_1 Choline kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009316 402.0
CMS2_k127_3350523_0 Signal peptide peptidase K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 443.0
CMS2_k127_3350523_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 416.0
CMS2_k127_3350523_2 rRNA methylase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 383.0
CMS2_k127_3350523_3 Chorismate synthase K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 332.0
CMS2_k127_3350523_4 multidrug K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000001989 242.0
CMS2_k127_3350523_5 Acetyltransferase (GNAT) family - - - 0.00000000000000000129 93.0
CMS2_k127_3350603_0 COG0744 Membrane carboxypeptidase (penicillin-binding protein) K05366 - 2.4.1.129,3.4.16.4 1.142e-196 629.0
CMS2_k127_3350603_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 384.0
CMS2_k127_3350603_2 Predicted membrane protein (DUF2238) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 299.0
CMS2_k127_3350603_3 reductase K00384 - 1.8.1.9 0.0000000000000000000000000000005464 123.0
CMS2_k127_335217_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 399.0
CMS2_k127_335217_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 380.0
CMS2_k127_335217_2 aminotransferase K00812,K12252 - 2.6.1.1,2.6.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000001121 252.0
CMS2_k127_335217_3 tetR family - - - 0.0000000000000000000000000000000000000000000000000000001691 214.0
CMS2_k127_3362013_0 Formate dehydrogenase subunit alpha - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 584.0
CMS2_k127_3362013_1 Ankyrin repeats (many copies) - - - 0.00000000002199 75.0
CMS2_k127_3376620_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 8.873e-264 818.0
CMS2_k127_3376620_1 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 363.0
CMS2_k127_3376620_2 ATPases associated with a variety of cellular activities K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 342.0
CMS2_k127_3376620_3 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001036 245.0
CMS2_k127_3376620_4 transport system auxiliary component K18480 - - 0.00000000000000000000000000000000000000000000005925 178.0
CMS2_k127_3376620_5 MlaD protein K02067,K06192 - - 0.000000000000000000000000000002201 124.0
CMS2_k127_3376620_6 Protein of unknown function (DUF1223) - - - 0.00000000000000000000000000006045 121.0
CMS2_k127_3376620_7 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins - - - 0.000000000000000000001445 99.0
CMS2_k127_3376620_8 Phospholipid N-methyltransferase - - - 0.00000000002488 73.0
CMS2_k127_3376620_9 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067,K06192 - - 0.000000001607 69.0
CMS2_k127_3385990_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 481.0
CMS2_k127_3385990_1 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000001308 213.0
CMS2_k127_3385990_2 zinc metalloprotease K11749 - - 0.00000000000000000000000000000005561 127.0
CMS2_k127_3386549_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.471e-283 887.0
CMS2_k127_3386549_1 TRAP transporter solute receptor TAXI family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004802 475.0
CMS2_k127_3386549_2 ABC transporter C-terminal domain K15738 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010528,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031323,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0070894,GO:0071944,GO:0080090,GO:0097159,GO:1901363 - 0.000000002194 59.0
CMS2_k127_3401494_0 PFAM D-galactarate dehydratase Altronate hydrolase, C terminus K01685 - 4.2.1.7 3.357e-247 770.0
CMS2_k127_3401494_1 Adenylate cyclase K01768 - 4.6.1.1 6.266e-238 751.0
CMS2_k127_3412814_0 Tripartite ATP-independent periplasmic transporter, DctM component K11690 GO:0005575,GO:0016020,GO:0016021,GO:0031224,GO:0044425 - 4.647e-226 709.0
CMS2_k127_3412814_1 Sigma-54 interaction domain K10126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 593.0
CMS2_k127_3412814_2 Bacterial extracellular solute-binding protein, family 7 K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 524.0
CMS2_k127_3412814_3 Histidine kinase K10125 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 357.0
CMS2_k127_3412814_4 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 330.0
CMS2_k127_3412814_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 320.0
CMS2_k127_3412814_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000003394 107.0
CMS2_k127_3412814_7 Sporulation related domain - - - 0.000001097 60.0
CMS2_k127_3426714_0 COG2217 Cation transport ATPase K17686 - 3.6.3.54 4.884e-215 691.0
CMS2_k127_3426714_1 COG0512 Anthranilate para-aminobenzoate synthases component II K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 297.0
CMS2_k127_3426714_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000005761 87.0
CMS2_k127_3429790_0 arylsulfatase A K01130 - 3.1.6.1 2.019e-207 650.0
CMS2_k127_3429790_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 518.0
CMS2_k127_3429790_2 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 398.0
CMS2_k127_3429790_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000002917 246.0
CMS2_k127_3429790_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K03438,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008961,GO:0009249,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000007784 218.0
CMS2_k127_3429790_5 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000001883 196.0
CMS2_k127_3438107_0 efflux pump - - - 0.0 1152.0
CMS2_k127_3438107_1 glucose sorbosone K00117,K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 1.1.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 441.0
CMS2_k127_3438107_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006255 265.0
CMS2_k127_3438107_3 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.0000000000000000000000000000000000000001937 151.0
CMS2_k127_344315_0 COG4584 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 569.0
CMS2_k127_344315_1 IstB-like ATP binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 390.0
CMS2_k127_3445224_0 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00263 - 1.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 426.0
CMS2_k127_3445224_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008832 414.0
CMS2_k127_3445224_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007104 284.0
CMS2_k127_3445224_3 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000003889 211.0
CMS2_k127_3445224_4 GDP-mannose mannosyl hydrolase activity - - - 0.00000000000000000000000000000000000000024 154.0
CMS2_k127_3445224_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000005842 145.0
CMS2_k127_3445224_6 alcohol dehydrogenase K00001,K00043 - 1.1.1.1,1.1.1.61 0.00000000000000002437 82.0
CMS2_k127_3460325_0 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 460.0
CMS2_k127_3460325_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000001292 267.0
CMS2_k127_3464413_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 5.557e-319 987.0
CMS2_k127_3464413_1 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 448.0
CMS2_k127_3464413_2 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 327.0
CMS2_k127_3464413_3 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000006998 259.0
CMS2_k127_3464413_4 GcrA cell cycle regulator K13583 - - 0.000000000000000000000000000000000001347 143.0
CMS2_k127_3464413_5 transcriptional regulators K22042 - - 0.0000000000000000000000000004164 119.0
CMS2_k127_3464413_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000002505 102.0
CMS2_k127_3464413_7 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000007224 93.0
CMS2_k127_3464413_8 small membrane protein - - - 0.000000000000000002401 90.0
CMS2_k127_3464413_9 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000009832 73.0
CMS2_k127_3475017_0 Belongs to the GcvT family K19191 - 1.5.3.19 0.0 1316.0
CMS2_k127_3475017_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 5e-323 998.0
CMS2_k127_3475017_2 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 2.765e-223 704.0
CMS2_k127_3475017_3 Belongs to the GcvT family K00315 - 1.5.8.4 0.0000000000000000007523 87.0
CMS2_k127_3486799_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 6.027e-239 747.0
CMS2_k127_3486799_1 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 556.0
CMS2_k127_3486799_2 4Fe-4S dicluster domain K00184,K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 393.0
CMS2_k127_3486799_3 DMSO reductase anchor subunit K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 299.0
CMS2_k127_3486799_4 Belongs to the MIP aquaporin (TC 1.A.8) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 296.0
CMS2_k127_3486799_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000008726 204.0
CMS2_k127_3486799_6 Protein of unknown function (DUF1491) - - - 0.0000000000000000000000000000002585 126.0
CMS2_k127_3508815_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2402.0
CMS2_k127_3508815_1 COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266 - 1.4.1.13,1.4.1.14 2.563e-239 748.0
CMS2_k127_3508815_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000003392 114.0
CMS2_k127_3518125_0 Bacterial regulatory helix-turn-helix protein, lysR family K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 427.0
CMS2_k127_3518125_1 - - - - 0.00000000000000000000003876 104.0
CMS2_k127_3518125_2 Cysteine dioxygenase type I - - - 0.000000000000001609 90.0
CMS2_k127_3532316_0 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 8.776e-208 658.0
CMS2_k127_3532316_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 595.0
CMS2_k127_3532316_2 Belongs to the peptidase S1C family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 522.0
CMS2_k127_3532316_3 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002357 202.0
CMS2_k127_3532316_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001073 147.0
CMS2_k127_3532316_5 Isochorismatase family - - - 0.00000000000000000003746 94.0
CMS2_k127_3538784_0 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000006282 222.0
CMS2_k127_3538784_1 Belongs to the UPF0260 family K09160 - - 0.00000000000000000000000000000000000000000000000000000000001172 212.0
CMS2_k127_3538784_2 Membrane K15977 - - 0.00000000000000000000000000000000000000000000003067 175.0
CMS2_k127_3540166_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 602.0
CMS2_k127_3540166_1 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 355.0
CMS2_k127_3540166_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 302.0
CMS2_k127_3540166_3 Protein required for attachment to host cells - - - 0.0000000000000000000000000000000008978 136.0
CMS2_k127_3546119_0 Histidine ammonia-lyase K01745 - 4.3.1.3 1.949e-215 689.0
CMS2_k127_3546119_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 609.0
CMS2_k127_3546119_2 N-formylglutamate amidohydrolase K01479 - 3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 337.0
CMS2_k127_3546119_3 imidazolonepropionase activity K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 308.0
CMS2_k127_3591301_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 526.0
CMS2_k127_3591301_1 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 353.0
CMS2_k127_3591301_2 Nitrile hydratase, alpha chain K01721 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 321.0
CMS2_k127_3591301_3 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 315.0
CMS2_k127_3591301_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02113,K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000494 166.0
CMS2_k127_3591301_5 Nitrile hydratase beta subunit - - - 0.00000000000000000000000000000008316 128.0
CMS2_k127_3591301_6 - - - - 0.0000000000009798 74.0
CMS2_k127_3591301_7 Zn_pept K01308 - 3.4.19.11 0.0000000002476 67.0
CMS2_k127_3593039_0 Cell division protein FtsI penicillin-binding protein 2 K03587 - 3.4.16.4 1.335e-200 642.0
CMS2_k127_3593039_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 370.0
CMS2_k127_3593039_2 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000005609 159.0
CMS2_k127_3593039_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000002828 160.0
CMS2_k127_3593039_4 periplasmic protein - - - 0.00000000000000000002014 98.0
CMS2_k127_3616343_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 8.912e-211 664.0
CMS2_k127_3616343_1 Spermidine putrescine-binding periplasmic protein K02055 - - 3.832e-200 627.0
CMS2_k127_3616343_2 5-aminolevulinic acid synthase K00643 - 2.3.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 563.0
CMS2_k127_3616343_3 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 549.0
CMS2_k127_3616343_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 531.0
CMS2_k127_3616343_5 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001935 259.0
CMS2_k127_3616343_6 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000301 244.0
CMS2_k127_3760448_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.858e-211 670.0
CMS2_k127_3760448_1 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 340.0
CMS2_k127_377432_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.517e-215 675.0
CMS2_k127_377432_1 phosphomannomutase K01840 - 5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 595.0
CMS2_k127_377432_2 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 436.0
CMS2_k127_377432_3 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 362.0
CMS2_k127_377432_4 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 289.0
CMS2_k127_377432_5 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000003188 214.0
CMS2_k127_377432_6 DnaJ molecular chaperone homology domain - - - 0.0000000000000000000000000000000000000000000000000000105 197.0
CMS2_k127_377432_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000007068 163.0
CMS2_k127_377432_8 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000003667 103.0
CMS2_k127_377432_9 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000002836 85.0
CMS2_k127_378947_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916 - 6.3.1.5 1.361e-243 763.0
CMS2_k127_378947_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 1.659e-239 746.0
CMS2_k127_378947_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 586.0
CMS2_k127_378947_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 492.0
CMS2_k127_378947_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 474.0
CMS2_k127_378947_5 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000002442 226.0
CMS2_k127_378947_6 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000002432 205.0
CMS2_k127_3842533_0 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 1.13e-213 677.0
CMS2_k127_3842533_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000009877 226.0
CMS2_k127_3842533_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000003316 169.0
CMS2_k127_3844059_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 301.0
CMS2_k127_3844059_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007471 251.0
CMS2_k127_3844059_2 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000008314 154.0
CMS2_k127_3870400_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 376.0
CMS2_k127_3870400_1 Pfam:Pyridox_oxidase K00275 - 1.4.3.5 0.0000000000000000000000000000001844 134.0
CMS2_k127_3870400_2 Protein conserved in bacteria - - - 0.000000000000000000000000009049 111.0
CMS2_k127_3870488_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 464.0
CMS2_k127_3870488_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000004564 214.0
CMS2_k127_3870488_2 Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress K01091 - 3.1.3.18 0.000000000000000000000000000001232 133.0
CMS2_k127_3885865_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 7.623e-229 715.0
CMS2_k127_3885865_1 Creatinase/Prolidase N-terminal domain K01262,K01271,K08688 - 3.4.11.9,3.4.13.9,3.5.3.3 7.776e-195 616.0
CMS2_k127_3885865_10 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000001205 67.0
CMS2_k127_3885865_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 442.0
CMS2_k127_3885865_3 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001295 277.0
CMS2_k127_3885865_4 COG1463 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000009511 190.0
CMS2_k127_3885865_5 NADH ubiquinone oxidoreductase 17.2 kD subunit - - - 0.000000000000000000000000000000000000000007147 160.0
CMS2_k127_3885865_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000004438 142.0
CMS2_k127_3885865_7 protein conserved in bacteria - - - 0.0000000000000000000000000000007701 128.0
CMS2_k127_3885865_8 EamA-like transporter family - - - 0.00000000000000000000000001015 127.0
CMS2_k127_3885865_9 - - - - 0.0000000000000000000000003454 106.0
CMS2_k127_3888402_0 AsmA family K07289,K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 323.0
CMS2_k127_3888402_1 COG5387 Chaperone required for the assembly of the mitochondrial F1-ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000569 224.0
CMS2_k127_390091_0 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 603.0
CMS2_k127_390091_1 Glycoside hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 416.0
CMS2_k127_390091_2 Acetyltransferase (GNAT) family - - - 0.00000001937 55.0
CMS2_k127_3944676_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 407.0
CMS2_k127_3944676_1 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 364.0
CMS2_k127_3944676_2 Lipopolysaccharide-assembly K03643 - - 0.00000000000000000000000001104 118.0
CMS2_k127_3944676_3 Secreted protein - - - 0.00000000000000000000000002487 111.0
CMS2_k127_3982826_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 597.0
CMS2_k127_3982826_1 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 372.0
CMS2_k127_3982826_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 356.0
CMS2_k127_3982826_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 334.0
CMS2_k127_3982826_4 protein conserved in bacteria K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000008789 236.0
CMS2_k127_3982826_5 response to cobalt ion - - - 0.0000000000005724 75.0
CMS2_k127_3996795_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 455.0
CMS2_k127_3996795_1 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 385.0
CMS2_k127_3996795_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 299.0
CMS2_k127_4004338_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 615.0
CMS2_k127_4004338_1 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 538.0
CMS2_k127_4004338_2 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001576 260.0
CMS2_k127_4004338_3 - - - - 0.000000001079 63.0
CMS2_k127_4017704_0 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 2.096e-212 683.0
CMS2_k127_402429_0 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 360.0
CMS2_k127_402429_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 347.0
CMS2_k127_402429_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000000000000771 204.0
CMS2_k127_402429_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000001624 87.0
CMS2_k127_402429_4 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000001581 64.0
CMS2_k127_4024657_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 6.451e-241 752.0
CMS2_k127_4024657_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000008311 236.0
CMS2_k127_4039982_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 4.861e-229 715.0
CMS2_k127_4039982_1 Bacterial extracellular solute-binding protein, family 7 - - - 1.496e-210 658.0
CMS2_k127_4039982_2 DeoR C terminal sensor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009014 263.0
CMS2_k127_4039982_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000001238 223.0
CMS2_k127_4039982_4 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000009148 111.0
CMS2_k127_406623_0 hydrolase of the metallo-beta-lactamase superfamily K12574 - - 5.402e-213 673.0
CMS2_k127_406623_1 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001957 254.0
CMS2_k127_406623_2 Methyladenine glycosylase - - - 0.0000000000000000000000000000006324 123.0
CMS2_k127_406623_3 Protein of unknown function (DUF1467) - - - 0.00000000000000000000000005009 109.0
CMS2_k127_4070131_0 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 373.0
CMS2_k127_4070131_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000002181 177.0
CMS2_k127_4076489_0 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 546.0
CMS2_k127_4076489_1 COG1194 A G-specific DNA glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 459.0
CMS2_k127_4076489_2 COG0475 Kef-type K transport systems, membrane components K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 410.0
CMS2_k127_4076489_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000004494 228.0
CMS2_k127_4076489_4 Protein of unknown function (DUF721) - - - 0.000000000000000000000000001342 118.0
CMS2_k127_4076489_5 - - - - 0.00008035 51.0
CMS2_k127_4080519_0 Protein conserved in bacteria K16514 - 5.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000884 527.0
CMS2_k127_4080519_1 GlcNAc-PI de-N-acetylase K16515 - 4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 436.0
CMS2_k127_4080519_2 Aldolase/RraA K02553,K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 342.0
CMS2_k127_4080519_3 Bacterial extracellular solute-binding protein K22003 - 5.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000001505 244.0
CMS2_k127_4080519_4 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000001526 221.0
CMS2_k127_4080519_5 DoxX K15977 - - 0.00000000000000000000000000000000000000000000000000000003476 198.0
CMS2_k127_4080519_6 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K13796 - - 0.00000000000000000000003818 99.0
CMS2_k127_4080519_7 Domain of unknown function (DUF1932) - - - 0.00000000127 63.0
CMS2_k127_4086849_0 COG1178 ABC-type Fe3 transport system, permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 545.0
CMS2_k127_4086849_1 Iron deficiency-induced protein A K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 449.0
CMS2_k127_4086849_2 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit - - - 0.0000000000000000000000000000000000000000000000000001131 190.0
CMS2_k127_4086849_3 Histidine phosphotransferase C-terminal domain K13588 - - 0.00000000000000000000000000000000003706 142.0
CMS2_k127_4086849_4 Protein of unknown function (DUF3553) - - - 0.000000000000000005796 86.0
CMS2_k127_4094969_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 511.0
CMS2_k127_4094969_1 Phosphomethylpyrimidine kinase K16370 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000001443 270.0
CMS2_k127_4094969_2 Exopolysaccharide synthesis ExoD - - - 0.000000000000000000000000000000000000001308 155.0
CMS2_k127_4094969_3 FAD binding domain - - - 0.000000000000000000000000000000000004056 139.0
CMS2_k127_4094969_4 - - - - 0.000005265 57.0
CMS2_k127_4094969_5 Transglutaminase-like domain - - - 0.0007461 50.0
CMS2_k127_410925_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 546.0
CMS2_k127_410925_1 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000003949 252.0
CMS2_k127_410925_2 Ferredoxin K04755 - - 0.0000000000000000000000000000000000000000000000000003374 186.0
CMS2_k127_410925_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000006283 134.0
CMS2_k127_410925_4 SCP-2 sterol transfer family - - - 0.000000000000000000000000203 115.0
CMS2_k127_410925_5 Phospholipase_D-nuclease N-terminal - - - 0.000000000008008 68.0
CMS2_k127_410925_6 Ribosomal protein L7/L12 C-terminal domain - - - 0.0009344 46.0
CMS2_k127_4116348_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.648e-212 665.0
CMS2_k127_4116348_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 372.0
CMS2_k127_4116348_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 355.0
CMS2_k127_4116348_3 COG0530 Ca2 Na antiporter K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 308.0
CMS2_k127_4116348_4 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000000000000000000001135 219.0
CMS2_k127_4116348_5 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity K03366,K13370 - 1.1.1.239,1.1.1.304,1.1.1.62,1.1.1.76 0.00000000000000000000000000000000000000000000000001924 180.0
CMS2_k127_4116348_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000429 134.0
CMS2_k127_4116348_7 Acetyltransferase (GNAT) family - - - 0.0000000000000000002196 91.0
CMS2_k127_4123591_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 394.0
CMS2_k127_4123591_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000002103 174.0
CMS2_k127_4123591_2 OsmC-like protein - - - 0.00000000000000000000000000000003428 130.0
CMS2_k127_4141625_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 501.0
CMS2_k127_4141625_1 Belongs to the helicase family. UvrD subfamily K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 449.0
CMS2_k127_4142976_0 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 445.0
CMS2_k127_4142976_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 387.0
CMS2_k127_4142976_2 Inner membrane protein PRK11099 K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 371.0
CMS2_k127_4142976_3 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.0000000000000000000000000000000000000000000000000000000000000000000000000000108 267.0
CMS2_k127_4142976_4 Class II Aldolase and Adducin N-terminal domain K22130 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000005009 258.0
CMS2_k127_4142976_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00019,K18335 - 1.1.1.30 0.00000000001324 64.0
CMS2_k127_4146218_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1153.0
CMS2_k127_4146218_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 1.657e-210 665.0
CMS2_k127_4146218_10 pathogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 392.0
CMS2_k127_4146218_11 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 362.0
CMS2_k127_4146218_12 Uracil-DNA glycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 309.0
CMS2_k127_4146218_13 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002426 273.0
CMS2_k127_4146218_14 flagellar motor protein K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002426 246.0
CMS2_k127_4146218_15 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000001937 226.0
CMS2_k127_4146218_16 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000614 223.0
CMS2_k127_4146218_17 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000000000000000000002692 190.0
CMS2_k127_4146218_18 MOSC domain - - - 0.000000000000000000000000000000000000000000000000002772 187.0
CMS2_k127_4146218_19 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000007939 137.0
CMS2_k127_4146218_2 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 568.0
CMS2_k127_4146218_20 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000002701 114.0
CMS2_k127_4146218_21 - - - - 0.00000000000000000000007884 102.0
CMS2_k127_4146218_22 - - - - 0.00000000003291 71.0
CMS2_k127_4146218_23 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0007059 53.0
CMS2_k127_4146218_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 553.0
CMS2_k127_4146218_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 533.0
CMS2_k127_4146218_5 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 472.0
CMS2_k127_4146218_6 Cysteine synthase K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 466.0
CMS2_k127_4146218_7 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 444.0
CMS2_k127_4146218_8 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 406.0
CMS2_k127_4146218_9 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 382.0
CMS2_k127_414973_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 524.0
CMS2_k127_414973_1 Porphyromonas-type peptidyl-arginine deiminase K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 421.0
CMS2_k127_4160551_0 ABC-type dipeptide transport system periplasmic component K02035 - - 2.018e-312 971.0
CMS2_k127_4160551_1 BCCT, betaine/carnitine/choline family transporter K03451 - - 5.238e-293 905.0
CMS2_k127_4160551_2 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 577.0
CMS2_k127_4160551_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 548.0
CMS2_k127_4160551_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 479.0
CMS2_k127_4160551_5 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 428.0
CMS2_k127_4160551_6 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000377 233.0
CMS2_k127_4160551_7 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000003528 194.0
CMS2_k127_4160551_8 Phosphomethylpyrimidine kinase K16370 - 2.7.1.11 0.00000000000000000000002872 103.0
CMS2_k127_4180646_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 4.785e-213 666.0
CMS2_k127_4180646_1 Belongs to the proline racemase family K01777 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0050346 5.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 519.0
CMS2_k127_4180646_10 CoA binding domain - - - 0.000000000007721 69.0
CMS2_k127_4180646_11 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000001946 61.0
CMS2_k127_4180646_2 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 489.0
CMS2_k127_4180646_3 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine K17735 - 1.1.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 464.0
CMS2_k127_4180646_4 MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 451.0
CMS2_k127_4180646_5 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 384.0
CMS2_k127_4180646_6 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001163 274.0
CMS2_k127_4180646_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001214 261.0
CMS2_k127_4180646_8 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000003263 250.0
CMS2_k127_4180646_9 META domain - - - 0.000000000006323 73.0
CMS2_k127_4194869_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 4.256e-210 659.0
CMS2_k127_4194869_1 - - - - 0.000000006635 61.0
CMS2_k127_4210412_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 3.572e-235 732.0
CMS2_k127_4210412_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 9.372e-208 664.0
CMS2_k127_4210412_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 430.0
CMS2_k127_4210412_3 pkhd-type hydroxylase K07336 - - 0.00000000000000000008763 90.0
CMS2_k127_4210427_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 405.0
CMS2_k127_4210427_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000003893 85.0
CMS2_k127_4212941_0 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 479.0
CMS2_k127_4212941_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 392.0
CMS2_k127_4212941_2 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 364.0
CMS2_k127_4212941_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 303.0
CMS2_k127_4212941_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000003884 231.0
CMS2_k127_4212941_5 Competence protein K02238 - - 0.00000000000000000000000001957 116.0
CMS2_k127_4244669_0 COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes K00164 - 1.2.4.2 0.0 1407.0
CMS2_k127_4244669_1 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000005567 241.0
CMS2_k127_4255053_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 0.0 1020.0
CMS2_k127_4255053_1 COG1960 Acyl-CoA dehydrogenases K00248 - 1.3.8.1 9.075e-270 842.0
CMS2_k127_4255053_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 469.0
CMS2_k127_4255053_3 Belongs to the thiolase family K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000005104 222.0
CMS2_k127_4255053_4 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000285 160.0
CMS2_k127_4255053_5 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000002575 141.0
CMS2_k127_4264869_0 Type I secretion membrane fusion protein, HlyD K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 373.0
CMS2_k127_4264869_1 Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000001546 198.0
CMS2_k127_4276434_0 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 560.0
CMS2_k127_4276434_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 483.0
CMS2_k127_4276434_2 protein conserved in bacteria K09796 - - 0.00000000000000000000000000002246 124.0
CMS2_k127_4276434_3 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.0004217 42.0
CMS2_k127_4290865_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.421e-319 981.0
CMS2_k127_4290865_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 1.109e-206 657.0
CMS2_k127_4290865_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003265 230.0
CMS2_k127_4290865_11 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000000000000000000000001741 209.0
CMS2_k127_4290865_12 Protein of unknown function (DUF983) - - - 0.0000000000000000000000000000000000000001513 153.0
CMS2_k127_4290865_13 of membrane protease K07340 - - 0.00000000000000000000000000000000007371 143.0
CMS2_k127_4290865_14 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000004711 117.0
CMS2_k127_4290865_15 Domain of unknown function (DUF4170) - - - 0.00000000000000000000001303 102.0
CMS2_k127_4290865_2 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 599.0
CMS2_k127_4290865_3 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 475.0
CMS2_k127_4290865_4 cytochrome c oxidase K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 446.0
CMS2_k127_4290865_5 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 435.0
CMS2_k127_4290865_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 422.0
CMS2_k127_4290865_7 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000237 282.0
CMS2_k127_4290865_8 Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005812 243.0
CMS2_k127_4290865_9 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000000000000000000000000000000000000006226 242.0
CMS2_k127_4298214_0 Bacterial extracellular solute-binding protein K17321 - - 3.344e-255 789.0
CMS2_k127_4298214_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 9.862e-240 750.0
CMS2_k127_4298214_10 PFAM regulatory protein ArsR - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000005313 122.0
CMS2_k127_4298214_11 - - - - 0.00000000000000000000003104 102.0
CMS2_k127_4298214_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 5.781e-228 716.0
CMS2_k127_4298214_3 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 563.0
CMS2_k127_4298214_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 557.0
CMS2_k127_4298214_5 multicopper oxidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 438.0
CMS2_k127_4298214_6 Transcriptional K02444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 348.0
CMS2_k127_4298214_7 NUDIX domain K00949 - 2.7.6.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001524 291.0
CMS2_k127_4298214_8 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006998 259.0
CMS2_k127_4298214_9 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000002608 235.0
CMS2_k127_4323101_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 432.0
CMS2_k127_4323101_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 346.0
CMS2_k127_4323101_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 291.0
CMS2_k127_4323101_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000904 243.0
CMS2_k127_4323101_4 imidazoleglycerol-phosphate dehydratase K00817,K01089,K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.9,3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000004452 167.0
CMS2_k127_4323101_5 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.00000000000000000000000000000002617 136.0
CMS2_k127_4323904_0 Belongs to the thiolase family K00626,K00632,K07823 - 2.3.1.16,2.3.1.174,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 354.0
CMS2_k127_4323904_1 High-affinity nickel-transport protein K08970 - - 0.0000000000000000000000000000000000000000000000000001054 198.0
CMS2_k127_4323904_2 Protein of unknown function (DUF1007) - - - 0.0000000000000000000000000000000002419 148.0
CMS2_k127_4323904_3 Ankyrin repeat K06867,K21440 - - 0.00004754 45.0
CMS2_k127_432772_0 Bacterial extracellular solute-binding protein K02055 - - 6.504e-208 650.0
CMS2_k127_432772_1 COG2041 Sulfite oxidase and related enzymes K17225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 355.0
CMS2_k127_432772_2 spermidine synthase activity K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 354.0
CMS2_k127_432772_3 cytochrome K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001424 272.0
CMS2_k127_432772_4 Belongs to the ABC transporter superfamily K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008592 253.0
CMS2_k127_4332487_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001775 278.0
CMS2_k127_4332487_1 - - - - 0.000000000000000000000309 100.0
CMS2_k127_4341263_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 5.746e-200 631.0
CMS2_k127_4341263_1 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000001118 268.0
CMS2_k127_4358849_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000718 264.0
CMS2_k127_4358849_1 response to hydrogen peroxide K09914 - - 0.0000000000000000000000000000000005298 141.0
CMS2_k127_4391935_0 Class II aldolase adducin family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 442.0
CMS2_k127_4391935_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007567 276.0
CMS2_k127_4391935_2 FCD - - - 0.0000000000000000000000000000000000000000000000001283 185.0
CMS2_k127_4391935_3 transcriptional regulator K08365 - - 0.0000000000000000000000000000000008615 134.0
CMS2_k127_4406395_0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit K13796 - - 1.487e-203 639.0
CMS2_k127_4406395_1 TIGRFAM CitB domain protein K13795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 433.0
CMS2_k127_4406395_2 Isocitrate/isopropylmalate dehydrogenase K00031,K00052,K07246 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.42,1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 360.0
CMS2_k127_4432350_0 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 488.0
CMS2_k127_4432350_1 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 470.0
CMS2_k127_4432350_2 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 361.0
CMS2_k127_4435378_0 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 583.0
CMS2_k127_4435378_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.0000000000000000000000000000000000000000000000000000000000008992 218.0
CMS2_k127_4435378_2 O-antigen - - - 0.000000000000002318 80.0
CMS2_k127_4439254_0 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 471.0
CMS2_k127_4439254_1 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 369.0
CMS2_k127_4441375_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 8.426e-277 864.0
CMS2_k127_4441375_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 6.881e-274 861.0
CMS2_k127_4441375_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 485.0
CMS2_k127_4441375_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 402.0
CMS2_k127_4441375_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000003504 227.0
CMS2_k127_4441375_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.0000000000000000000000006131 107.0
CMS2_k127_4479860_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1285.0
CMS2_k127_4479860_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 344.0
CMS2_k127_4479860_2 peptidylprolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000002041 237.0
CMS2_k127_4482927_0 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 387.0
CMS2_k127_4482927_1 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000007419 215.0
CMS2_k127_4482927_2 Isochorismatase family - - - 0.000000000000000000000000000000002421 133.0
CMS2_k127_4482927_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000003992 126.0
CMS2_k127_4482927_4 AsmA-like C-terminal region K07290 - - 0.000000000000002177 79.0
CMS2_k127_4486203_0 COG1853 Conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002493 281.0
CMS2_k127_4486203_1 Protein of unknown function (DUF4011) - - - 0.0000000000006666 81.0
CMS2_k127_4519628_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 477.0
CMS2_k127_4519628_1 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 304.0
CMS2_k127_4519628_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000293 242.0
CMS2_k127_4519628_3 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000002676 254.0
CMS2_k127_4519628_4 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000742 243.0
CMS2_k127_4519628_5 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000003829 174.0
CMS2_k127_4519628_6 Aminoacyl-tRNA editing domain - - - 0.000000000000000000000000000000000000000000001813 167.0
CMS2_k127_4519628_7 Phasin protein - - - 0.00000000000000000000000000002547 123.0
CMS2_k127_4524151_0 FAD dependent oxidoreductase central domain - - - 2.628e-217 682.0
CMS2_k127_4524151_1 COG0646 Methionine synthase I (cobalamin-dependent), methyltransferase domain K00544,K00548 - 2.1.1.13,2.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 427.0
CMS2_k127_4540784_0 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 0.0 1116.0
CMS2_k127_4540784_1 COG3901 Regulator of nitric oxide reductase transcription K19339 - - 1.054e-306 950.0
CMS2_k127_4540784_10 homoserine kinase type II (protein kinase fold) - - - 0.0000000000000000000000000000000000000000000000002232 190.0
CMS2_k127_4540784_2 COG3420 Nitrous oxidase accessory protein K07218 - - 4.573e-199 627.0
CMS2_k127_4540784_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 418.0
CMS2_k127_4540784_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 398.0
CMS2_k127_4540784_5 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992,K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 347.0
CMS2_k127_4540784_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002008 287.0
CMS2_k127_4540784_7 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004286 276.0
CMS2_k127_4540784_8 ASCH - - - 0.0000000000000000000000000000000000000000000000000000000003344 204.0
CMS2_k127_4540784_9 NosL K19342 - - 0.00000000000000000000000000000000000000000000000000000002597 208.0
CMS2_k127_4543727_0 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 390.0
CMS2_k127_4543727_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 296.0
CMS2_k127_4543727_2 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 290.0
CMS2_k127_4543727_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000006201 208.0
CMS2_k127_4543727_4 Sulfotransferase family K01014 - 2.8.2.1 0.0000000000000000000000000000000000000000002861 167.0
CMS2_k127_4543727_5 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000001021 152.0
CMS2_k127_4543909_0 NnrS protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 306.0
CMS2_k127_4543909_1 FMN_bind K19339 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001401 258.0
CMS2_k127_4543909_2 Transcriptional regulator K13771 - - 0.0000000000000000000000000000000000000000000002308 172.0
CMS2_k127_4548293_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.203e-250 782.0
CMS2_k127_4548293_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000009536 133.0
CMS2_k127_4548293_2 Acetyltransferase (GNAT) domain - - - 0.000000001124 66.0
CMS2_k127_4565623_0 Surface antigen K07278 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 436.0
CMS2_k127_4565623_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000002606 249.0
CMS2_k127_457259_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 574.0
CMS2_k127_457259_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000001091 214.0
CMS2_k127_457259_2 ammonia monooxygenase K07120 - - 0.00000000000000000000000000000000000000000000000000000000006285 218.0
CMS2_k127_4578160_0 Predicted membrane protein (DUF2142) - - - 0.00000002656 66.0
CMS2_k127_4581995_0 Belongs to the GcvT family K00315 - 1.5.8.4 5e-324 996.0
CMS2_k127_4592998_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1034.0
CMS2_k127_4592998_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 580.0
CMS2_k127_4592998_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 565.0
CMS2_k127_4592998_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003376 243.0
CMS2_k127_4592998_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000001066 185.0
CMS2_k127_4592998_6 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000004703 85.0
CMS2_k127_4592998_7 Excinuclease abc c subunit domain protein K07461 - - 0.00007437 47.0
CMS2_k127_4595407_0 Domain of unknown function (DUF4445) - - - 3.544e-281 872.0
CMS2_k127_4595407_1 Trimethylamine methyltransferase (MTTB) - - - 6.129e-268 833.0
CMS2_k127_4595407_2 Belongs to the GcvT family K00302 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 462.0
CMS2_k127_4595407_3 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00651 - 2.3.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 383.0
CMS2_k127_4595407_4 LysE type translocator - - - 0.0000000000000000000000000000000000000000003128 168.0
CMS2_k127_4595407_5 Sarcosine oxidase, gamma subunit family K00305 - 1.5.3.1 0.0000000000000000000000000000000000000000007425 164.0
CMS2_k127_4595407_6 - - - - 0.0000000000000000003745 98.0
CMS2_k127_4599374_0 OsmC-like protein K06889,K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 511.0
CMS2_k127_4599374_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000006386 166.0
CMS2_k127_4602882_0 Cysteine-rich domain K11473 - - 6.196e-212 665.0
CMS2_k127_4602882_1 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 522.0
CMS2_k127_4602882_10 Protein of unknown function (DUF3052) - - - 0.00000001409 63.0
CMS2_k127_4602882_2 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 459.0
CMS2_k127_4602882_3 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 386.0
CMS2_k127_4602882_4 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 361.0
CMS2_k127_4602882_5 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000025 281.0
CMS2_k127_4602882_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000004397 195.0
CMS2_k127_4602882_7 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000619 183.0
CMS2_k127_4602882_8 COG0457 FOG TPR repeat - - - 0.00000000000000000008496 91.0
CMS2_k127_4602882_9 COG0457 FOG TPR repeat - - - 0.00000000000006548 75.0
CMS2_k127_4607971_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 552.0
CMS2_k127_4607971_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 285.0
CMS2_k127_4631052_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.064e-312 971.0
CMS2_k127_4631052_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 474.0
CMS2_k127_4631052_10 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000002451 124.0
CMS2_k127_4631052_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 424.0
CMS2_k127_4631052_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 404.0
CMS2_k127_4631052_4 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 308.0
CMS2_k127_4631052_5 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 300.0
CMS2_k127_4631052_6 hydrolase (HAD superfamily) K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007373 282.0
CMS2_k127_4631052_7 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000594 233.0
CMS2_k127_4631052_8 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000002558 199.0
CMS2_k127_4631052_9 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K13940 - 2.7.6.3,4.1.2.25 0.000000000000000000000000000000000000000000001627 171.0
CMS2_k127_4640509_0 Na+/Pi-cotransporter K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 556.0
CMS2_k127_4640509_1 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 319.0
CMS2_k127_4640509_2 Domain of unknown function (DUF1476) - - - 0.000000000000000000000000000000000000000001173 158.0
CMS2_k127_4640509_3 DNA helicase - - - 0.00000000000000000000000000000000000000005886 156.0
CMS2_k127_4640509_4 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000000000000000000006594 110.0
CMS2_k127_46428_0 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 344.0
CMS2_k127_46428_1 Dicarboxylate transport - - - 0.000000000000000000000000000000000172 154.0
CMS2_k127_4665462_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 2.502e-196 618.0
CMS2_k127_4665462_1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 317.0
CMS2_k127_4665462_2 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000001601 187.0
CMS2_k127_4665462_3 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000578 165.0
CMS2_k127_4690374_0 Tripartite tricarboxylate transporter TctB family - - - 5.284e-304 944.0
CMS2_k127_4690374_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 535.0
CMS2_k127_4690374_2 Belongs to the TPP enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 432.0
CMS2_k127_4690374_3 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000967 365.0
CMS2_k127_4690374_4 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000002173 158.0
CMS2_k127_4690516_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 483.0
CMS2_k127_4690516_1 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 436.0
CMS2_k127_4690516_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 400.0
CMS2_k127_4690516_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002448 284.0
CMS2_k127_4690516_4 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000009987 244.0
CMS2_k127_4690516_5 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000002326 177.0
CMS2_k127_4690516_6 hydrolase - - - 0.0000000000000000000000000008804 118.0
CMS2_k127_4690516_7 - - - - 0.000000000000001173 85.0
CMS2_k127_4690516_8 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00005736 46.0
CMS2_k127_4710917_0 Biotin carboxylase C-terminal domain K01965,K01968,K13777 - 6.4.1.3,6.4.1.4,6.4.1.5 3.89e-238 756.0
CMS2_k127_4710917_1 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 432.0
CMS2_k127_4710917_2 Ion transport 2 domain protein - - - 0.000000000000000000000000000000000000000000000000000000002229 214.0
CMS2_k127_4710917_3 Enoyl-CoA hydratase K13766 - 4.2.1.18 0.000000000000000000000000000000000002586 141.0
CMS2_k127_4710917_4 Protein of unknown function (DUF1489) - - - 0.000000000000000000000000000000000005415 147.0
CMS2_k127_4753933_0 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 449.0
CMS2_k127_4753933_1 cytochrome c oxidase subunit II K02275 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0042773,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 394.0
CMS2_k127_4753933_2 Adenylosuccinate lyase C-terminus K01756,K01857 - 4.3.2.2,5.5.1.2 0.0000000000000000000000000000000000002057 149.0
CMS2_k127_475919_0 Efflux pump membrane transporter K03296 - - 0.0 1450.0
CMS2_k127_475919_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K19595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 385.0
CMS2_k127_475919_2 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000005886 178.0
CMS2_k127_475919_3 fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000004 111.0
CMS2_k127_4760786_0 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 396.0
CMS2_k127_4760786_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000000007488 149.0
CMS2_k127_4760786_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000001972 141.0
CMS2_k127_4760786_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000001518 102.0
CMS2_k127_4770566_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 310.0
CMS2_k127_4770566_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 325.0
CMS2_k127_4770566_2 protein, possibly involved in utilization of glycolate and propanediol - - - 0.000000000000000000000000000000000000000000000001993 189.0
CMS2_k127_4773645_0 Histidine kinase-like ATPases K14980 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 412.0
CMS2_k127_4773645_1 Transcriptional regulatory protein, C terminal K14981 - - 0.00000000000000000000000000000000000000000000000001552 183.0
CMS2_k127_4775946_0 Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism K00380,K02567 - 1.8.1.2 1.169e-240 749.0
CMS2_k127_4775946_1 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.00000000000000000000000000000000000000000000000957 179.0
CMS2_k127_4775946_2 4Fe-4S dicluster domain K02572 - - 0.00000000000000000000000000000000000000000000002342 179.0
CMS2_k127_4775946_3 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000004667 126.0
CMS2_k127_4775946_4 NapD protein K02570 - - 0.000000001621 64.0
CMS2_k127_4775946_5 nitrate reductase K02571 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000002746 62.0
CMS2_k127_4783286_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 553.0
CMS2_k127_4783286_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 520.0
CMS2_k127_4783286_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 338.0
CMS2_k127_4783286_3 Belongs to the HpcH HpaI aldolase family K00979,K02510 - 2.7.7.38,4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000006963 233.0
CMS2_k127_4783286_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000006171 128.0
CMS2_k127_4783286_6 - - - - 0.0000003517 57.0
CMS2_k127_4785555_0 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 405.0
CMS2_k127_4785555_1 Glucokinase K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000301 286.0
CMS2_k127_4785555_2 COG0363 6-phosphogluconolactonase Glucosamine-6-phosphate isomerase deaminase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000000007176 223.0
CMS2_k127_4785555_3 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.00000000000000000000000000000000002859 141.0
CMS2_k127_4785555_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000137 87.0
CMS2_k127_4790503_0 TRAP transporter, 4TM 12TM fusion protein - - - 0.0 1235.0
CMS2_k127_4790503_1 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 477.0
CMS2_k127_4790503_2 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 327.0
CMS2_k127_4790503_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 320.0
CMS2_k127_4790503_4 Sulfatase-modifying factor enzyme 1 K20333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 316.0
CMS2_k127_4790503_5 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000081 278.0
CMS2_k127_4790503_6 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000000000000000007493 181.0
CMS2_k127_4790503_7 Rhodanese Homology Domain - - - 0.00000000000000000000000000001053 126.0
CMS2_k127_4795646_0 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 555.0
CMS2_k127_4795646_1 ABC-type spermidine putrescine transport system, permease component I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 422.0
CMS2_k127_4795646_2 ABC-type spermidine putrescine transport system, permease component II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 357.0
CMS2_k127_4799693_0 Cytochrome c554 and c-prime - - - 9.567e-214 687.0
CMS2_k127_4799693_1 Arylsulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 436.0
CMS2_k127_4799693_2 Berberine and berberine like - - - 0.000000002856 58.0
CMS2_k127_4810573_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.0 1008.0
CMS2_k127_4810573_1 Adenylate and Guanylate cyclase catalytic domain - - - 2.922e-207 687.0
CMS2_k127_4810573_2 oxidase, subunit K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 390.0
CMS2_k127_4810573_3 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 352.0
CMS2_k127_4810573_4 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000004135 191.0
CMS2_k127_4810573_5 small integral membrane protein - - - 0.00000000000000000000000000000000000000002679 154.0
CMS2_k127_4810573_6 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000006545 126.0
CMS2_k127_4829711_0 reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 418.0
CMS2_k127_4829711_1 Nucleotidyl transferase K00966,K00992 - 2.7.7.13,2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000001753 287.0
CMS2_k127_4829711_2 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000002095 224.0
CMS2_k127_4829711_3 ATPase or kinase K06925,K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000004172 168.0
CMS2_k127_483979_0 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 1.165e-213 666.0
CMS2_k127_483979_1 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 316.0
CMS2_k127_483979_2 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000001342 198.0
CMS2_k127_483979_3 Belongs to the GcvT family - - - 0.0000000000000000000000000000001326 125.0
CMS2_k127_4866619_0 ABC transporter, ATP-binding protein K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 418.0
CMS2_k127_4866619_1 SIS domain K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 411.0
CMS2_k127_4866619_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 357.0
CMS2_k127_4866619_3 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 286.0
CMS2_k127_4866619_4 OstA-like protein K09774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007052 250.0
CMS2_k127_4866619_5 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002182 240.0
CMS2_k127_4866619_6 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000003746 237.0
CMS2_k127_4866619_7 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000000000000000000000000000000808 205.0
CMS2_k127_4866619_8 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.000000000000000000000000000000000000004042 156.0
CMS2_k127_4866619_9 Protein of unknown function (DUF1150) - - - 0.0000000001566 66.0
CMS2_k127_486879_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.272e-282 876.0
CMS2_k127_486879_1 COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K13598 - 2.7.13.3 1.333e-242 770.0
CMS2_k127_486879_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000108 163.0
CMS2_k127_486879_11 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000000009455 151.0
CMS2_k127_486879_2 Potassium transporter peripheral membrane component K03499 - - 2.99e-230 719.0
CMS2_k127_486879_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K13599 - - 1.012e-203 642.0
CMS2_k127_486879_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 535.0
CMS2_k127_486879_5 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 451.0
CMS2_k127_486879_6 Bacterial regulatory helix-turn-helix protein, lysR family K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 288.0
CMS2_k127_486879_7 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009767 285.0
CMS2_k127_486879_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K16066 - 1.1.1.381 0.0000000000000000000000000000000000000000000000000000000000000000000000000002797 258.0
CMS2_k127_486879_9 HAD-superfamily hydrolase subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000001053 220.0
CMS2_k127_4879940_0 Belongs to the HpcH HpaI aldolase family K08691 - 4.1.3.24,4.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 377.0
CMS2_k127_4879940_1 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 357.0
CMS2_k127_4879940_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004815 267.0
CMS2_k127_4884923_0 COG1653 ABC-type sugar transport system, periplasmic component K17321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 527.0
CMS2_k127_4884923_1 Belongs to the ABC transporter superfamily K17325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 501.0
CMS2_k127_4884923_2 COG1175 ABC-type sugar transport systems permease components K17322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 479.0
CMS2_k127_4884923_3 Belongs to the ABC transporter superfamily K17324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 461.0
CMS2_k127_4884923_4 Binding-protein-dependent transport system inner membrane component K17323 - - 0.0000000000000000105 83.0
CMS2_k127_4897484_0 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 451.0
CMS2_k127_4897484_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 443.0
CMS2_k127_4897484_2 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 316.0
CMS2_k127_4897484_3 17 kDa outer membrane surface antigen - - - 0.00000000000000000000000000000000000000000000000000001976 198.0
CMS2_k127_4897484_4 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000001457 90.0
CMS2_k127_490073_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 567.0
CMS2_k127_490073_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01928,K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 477.0
CMS2_k127_490073_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 428.0
CMS2_k127_490073_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 346.0
CMS2_k127_4922840_0 AAA domain, putative AbiEii toxin, Type IV TA system K16784 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008597 265.0
CMS2_k127_4922840_1 Protein of unknown function (DUF3095) - - - 0.0000000000000000000000000000000000000000000000000000000000000005213 226.0
CMS2_k127_4922840_3 Cobalt transport protein K16783 - - 0.0000000008591 62.0
CMS2_k127_4931356_0 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 526.0
CMS2_k127_4931356_1 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 422.0
CMS2_k127_4931356_2 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 294.0
CMS2_k127_4934626_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000006644 260.0
CMS2_k127_4934626_1 Aldehyde dehydrogenase family K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000106 190.0
CMS2_k127_4934626_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000007546 187.0
CMS2_k127_4934626_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000008714 149.0
CMS2_k127_4937395_0 NAD-specific glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1731.0
CMS2_k127_4937395_1 Pfam Glycosyl transferase family 2 K12990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 326.0
CMS2_k127_4937395_2 L,D-transpeptidase catalytic domain K21470 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007099 258.0
CMS2_k127_4937395_3 Methyltransferase domain - - - 0.00000000000000000000000000000000002953 141.0
CMS2_k127_495269_0 AMP-binding enzyme C-terminal domain K00666,K02182 - 6.2.1.48 2.514e-269 837.0
CMS2_k127_495269_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 497.0
CMS2_k127_495269_2 Mitochondrial fission ELM1 K07276 - - 0.00000000000000000000000000000000000000000000001583 177.0
CMS2_k127_495269_3 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0000000000000001322 80.0
CMS2_k127_4969545_0 ammonia monooxygenase K07120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 328.0
CMS2_k127_4969545_1 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000001043 194.0
CMS2_k127_4969545_2 - - - - 0.0000000000000000001125 91.0
CMS2_k127_4982719_0 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 317.0
CMS2_k127_4982719_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006836 265.0
CMS2_k127_4982719_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01487,K11991 - 3.5.4.1,3.5.4.3,3.5.4.33 0.000000000000000000000000000000000000000000000000000000002842 211.0
CMS2_k127_4982719_3 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000001463 68.0
CMS2_k127_4995313_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 590.0
CMS2_k127_4995313_1 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 494.0
CMS2_k127_4995313_2 COG0436 Aspartate tyrosine aromatic aminotransferase K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 419.0
CMS2_k127_4995313_3 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 380.0
CMS2_k127_4995313_4 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 353.0
CMS2_k127_4995313_5 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000009873 184.0
CMS2_k127_5026506_0 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 337.0
CMS2_k127_5026506_1 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000008301 215.0
CMS2_k127_5026506_2 Ankyrin repeat K06867,K21440 - - 0.000009178 50.0
CMS2_k127_5034294_0 COG2873 O-acetylhomoserine sulfhydrylase - - - 6.471e-205 646.0
CMS2_k127_5034294_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 509.0
CMS2_k127_5034294_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 493.0
CMS2_k127_5034294_3 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 427.0
CMS2_k127_5034294_4 Belongs to the iron ascorbate-dependent oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 428.0
CMS2_k127_5034294_5 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 317.0
CMS2_k127_5034294_6 PFAM Dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 303.0
CMS2_k127_5034294_7 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 295.0
CMS2_k127_5034294_8 Glutathione S-Transferase K00799 GO:0003674,GO:0003824,GO:0004364,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016740,GO:0016765,GO:0030611,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114 2.5.1.18 0.0000000000000000000000000000000000000000007856 166.0
CMS2_k127_5034294_9 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000000003404 80.0
CMS2_k127_5045792_0 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 516.0
CMS2_k127_5045792_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.000000000000000000000004898 102.0
CMS2_k127_5045792_2 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000003818 87.0
CMS2_k127_5065210_0 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 321.0
CMS2_k127_5065210_1 to the N-terminal domain of Lon protease K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000001169 234.0
CMS2_k127_5065210_2 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000000000001691 224.0
CMS2_k127_5065210_3 Protein of unknown function (DUF971) - - - 0.0000000000000000000000007776 110.0
CMS2_k127_5065210_4 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000002282 100.0
CMS2_k127_5065210_5 TIGRFAM methyltransferase FkbM family - - - 0.00000000000000000003491 98.0
CMS2_k127_5073833_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 5.653e-234 745.0
CMS2_k127_5073833_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.118e-194 624.0
CMS2_k127_5073833_2 SAF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 612.0
CMS2_k127_5073833_3 Sugar (and other) transporter K07552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 389.0
CMS2_k127_5073833_4 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 366.0
CMS2_k127_5073833_5 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000000000000000000000004259 189.0
CMS2_k127_5073833_6 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000004815 147.0
CMS2_k127_5073833_7 COG1925 Phosphotransferase system, HPr-related proteins K11189 - - 0.00000000000000000000000001136 119.0
CMS2_k127_5073833_8 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000001526 83.0
CMS2_k127_5096095_0 His Kinase A (phosphoacceptor) domain - - - 1.936e-317 1003.0
CMS2_k127_5096095_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008829 571.0
CMS2_k127_5096095_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000003687 135.0
CMS2_k127_5096095_3 Glycosyl transferase, family 2 - - - 0.00000000000000006654 81.0
CMS2_k127_509965_0 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 466.0
CMS2_k127_509965_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 309.0
CMS2_k127_509965_2 KR domain - - - 0.00000000000000004499 86.0
CMS2_k127_5102376_0 hydrolase, TatD family' K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 352.0
CMS2_k127_5102376_1 DNA polymerase III subunit delta K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 344.0
CMS2_k127_5102376_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000111 204.0
CMS2_k127_5102376_3 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.000000000000004472 77.0
CMS2_k127_5105039_0 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 454.0
CMS2_k127_5105039_1 protein conserved in bacteria K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 454.0
CMS2_k127_5105039_2 Taurine catabolism dioxygenase TauD, TfdA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 445.0
CMS2_k127_5105039_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 428.0
CMS2_k127_5105039_4 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 352.0
CMS2_k127_5105039_5 LexA-binding, inner membrane-associated putative hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 337.0
CMS2_k127_5105039_6 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000002448 237.0
CMS2_k127_5105039_7 Dimethlysulfonioproprionate lyase - - - 0.0000000000000000000000119 108.0
CMS2_k127_5105039_8 cyclic nucleotide-binding - - - 0.000001102 55.0
CMS2_k127_5115773_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 4.482e-214 676.0
CMS2_k127_5115773_1 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 401.0
CMS2_k127_5115773_2 COG2059 Chromate transport protein ChrA K07240 - - 0.000000000000000000000000000000000000000000000000001151 193.0
CMS2_k127_5115773_3 Polymer-forming cytoskeletal - - - 0.00000000000000000000003299 109.0
CMS2_k127_5147523_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 311.0
CMS2_k127_5147523_1 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 303.0
CMS2_k127_5147523_2 - - - - 0.0000000000000000000000000000000004518 149.0
CMS2_k127_5150970_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 5.176e-236 735.0
CMS2_k127_5150970_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 402.0
CMS2_k127_5150970_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 325.0
CMS2_k127_5150970_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 308.0
CMS2_k127_5150970_4 Protein conserved in bacteria K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 296.0
CMS2_k127_5150970_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000001968 233.0
CMS2_k127_5150970_6 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000008727 136.0
CMS2_k127_5150970_7 - - - - 0.0000000000000000000000000000005353 130.0
CMS2_k127_5163961_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1123.0
CMS2_k127_5163961_1 Branched-chain amino acid transport system / permease component K01997,K01998,K11960 - - 2.516e-247 777.0
CMS2_k127_5163961_10 Chalcone and stilbene synthases, C-terminal domain K16167 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 355.0
CMS2_k127_5163961_11 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 316.0
CMS2_k127_5163961_12 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 317.0
CMS2_k127_5163961_13 branched-chain amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 330.0
CMS2_k127_5163961_14 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 280.0
CMS2_k127_5163961_15 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004513 299.0
CMS2_k127_5163961_16 Isoprenylcysteine carboxyl methyltransferase (ICMT) family K16168 - - 0.000000000000000000000000000000000000000000000000000000000001356 220.0
CMS2_k127_5163961_17 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000003749 201.0
CMS2_k127_5163961_18 ThiS family K03636 - - 0.00000000000000000004723 91.0
CMS2_k127_5163961_19 protein conserved in bacteria - - - 0.000000000000000001085 91.0
CMS2_k127_5163961_2 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 2.664e-220 695.0
CMS2_k127_5163961_3 ABC transporter K02056 - 3.6.3.17 3.755e-218 687.0
CMS2_k127_5163961_4 ABC-type transport system, periplasmic component surface lipoprotein K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 536.0
CMS2_k127_5163961_5 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 544.0
CMS2_k127_5163961_6 Belongs to the 5'-nucleotidase family K01081,K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 522.0
CMS2_k127_5163961_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 513.0
CMS2_k127_5163961_8 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 485.0
CMS2_k127_5163961_9 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 360.0
CMS2_k127_5187533_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000005208 203.0
CMS2_k127_5187533_1 - - - - 0.000000000000000000001906 104.0
CMS2_k127_5191040_0 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 384.0
CMS2_k127_5191040_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000004146 283.0
CMS2_k127_5191040_2 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000001619 229.0
CMS2_k127_5191040_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000006131 209.0
CMS2_k127_5191040_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000003964 136.0
CMS2_k127_5191630_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.622e-217 681.0
CMS2_k127_5191630_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000002851 232.0
CMS2_k127_5191630_2 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000002027 220.0
CMS2_k127_5191630_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000002592 100.0
CMS2_k127_5212193_0 COG4547 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase) K09883 - 6.6.1.2 2.793e-249 785.0
CMS2_k127_5212193_1 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 383.0
CMS2_k127_5212193_2 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.00000000000000000000000000000000000000000000001795 171.0
CMS2_k127_5212193_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000006926 166.0
CMS2_k127_5212193_4 DinB family - - - 0.0000000000000000000000000000000000000007075 154.0
CMS2_k127_5212193_5 Aminotransferase class I and II - - - 0.0000000000000000000000009532 105.0
CMS2_k127_5225888_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 4.564e-230 723.0
CMS2_k127_5225888_1 COG0744 Membrane carboxypeptidase (penicillin-binding protein) K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000001039 110.0
CMS2_k127_5257471_0 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 527.0
CMS2_k127_5257471_1 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 482.0
CMS2_k127_5257471_2 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 346.0
CMS2_k127_5257471_3 Dak2 K05879 - 2.7.1.121 0.0000000000000000000000000000000000000000000000000001139 195.0
CMS2_k127_5257471_4 PTS system fructose IIA component - - - 0.000000000000000000000000000000000000000000000001582 185.0
CMS2_k127_5257471_5 Phosphotransferase System K11189 - - 0.00000000000000196 85.0
CMS2_k127_5257471_6 - - - - 0.000000000002695 78.0
CMS2_k127_5279334_0 DEAD/H associated K03724 - - 0.0 1157.0
CMS2_k127_5279334_1 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 497.0
CMS2_k127_5279334_2 Calcineurin-like phosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001183 266.0
CMS2_k127_5279334_3 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.0000000000000000000000000000000000000000000000000005284 190.0
CMS2_k127_5279334_4 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.00000000000000000000000000000000000000002349 160.0
CMS2_k127_5279334_5 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000002678 122.0
CMS2_k127_5279334_6 ATP dependent DNA ligase C terminal region K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000126 82.0
CMS2_k127_5281589_0 L,D-transpeptidase catalytic domain K21470 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 373.0
CMS2_k127_5281589_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 301.0
CMS2_k127_5281589_2 Protein of unknown function (DUF1194) - - - 0.00000000000000000000000000000000000000000000000000000000000000005289 247.0
CMS2_k127_5281589_3 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000005776 167.0
CMS2_k127_5281589_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000005507 153.0
CMS2_k127_5311274_0 ABC-type multidrug transport system ATPase and permease K02021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 404.0
CMS2_k127_5311274_1 S-adenosyl-L-methionine methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000002114 212.0
CMS2_k127_5311274_2 cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000003833 185.0
CMS2_k127_5311274_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000003144 175.0
CMS2_k127_53162_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 1.175e-295 923.0
CMS2_k127_53162_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 416.0
CMS2_k127_53162_2 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000000003369 101.0
CMS2_k127_53162_3 Protein of unknown function (DUF502) - - - 0.0002177 44.0
CMS2_k127_5319577_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 7.93e-243 757.0
CMS2_k127_5319577_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003157 264.0
CMS2_k127_5327867_0 ABC-type multidrug transport system, ATPase and permease K06147,K11085 - - 1.171e-219 704.0
CMS2_k127_5327867_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 435.0
CMS2_k127_5327867_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 442.0
CMS2_k127_5327867_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 434.0
CMS2_k127_5327867_4 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01907 - 6.2.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 406.0
CMS2_k127_5327867_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 320.0
CMS2_k127_5327867_6 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000006867 218.0
CMS2_k127_5327867_7 protein conserved in bacteria K09778 - - 0.00000000000000000000000000000000000000000000000000000111 208.0
CMS2_k127_5327867_8 COG1560 Lauroyl myristoyl acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000001715 203.0
CMS2_k127_5327867_9 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.00000000000000000000000001222 109.0
CMS2_k127_534229_0 - - - - 0.00000000000000000000000000000000006945 153.0
CMS2_k127_5357638_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.206e-230 721.0
CMS2_k127_5357638_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 9.915e-208 655.0
CMS2_k127_5357638_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 611.0
CMS2_k127_5357638_3 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 512.0
CMS2_k127_5357638_4 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 427.0
CMS2_k127_5357638_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 387.0
CMS2_k127_5357638_6 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 367.0
CMS2_k127_5357638_7 membrane protein, required for colicin V production K03558 - - 0.000000000000000000000000000000000000000000000000000001795 200.0
CMS2_k127_5357638_8 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000002501 102.0
CMS2_k127_5442799_0 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 329.0
CMS2_k127_5442799_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000002709 243.0
CMS2_k127_544832_0 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 360.0
CMS2_k127_544832_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000006874 207.0
CMS2_k127_544832_2 - - - - 0.0000008307 55.0
CMS2_k127_5459710_0 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 579.0
CMS2_k127_5459710_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000003198 145.0
CMS2_k127_5473871_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1444.0
CMS2_k127_5473871_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.799e-201 637.0
CMS2_k127_5473871_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 327.0
CMS2_k127_5473871_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 310.0
CMS2_k127_5473871_4 EamA-like transporter family K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002184 280.0
CMS2_k127_5473871_5 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000009827 134.0
CMS2_k127_5480357_0 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 488.0
CMS2_k127_5480357_1 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 355.0
CMS2_k127_5480357_2 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000191 265.0
CMS2_k127_5480357_3 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000002527 239.0
CMS2_k127_5480357_4 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000008479 213.0
CMS2_k127_5480357_5 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000000000000601 172.0
CMS2_k127_5480357_6 Aminotransferase class-III K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.000000000000000000000004016 108.0
CMS2_k127_5480357_7 Protein of unknown function (DUF1289) K06938 - - 0.0000000000000000000006154 98.0
CMS2_k127_5481342_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 520.0
CMS2_k127_5481342_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 385.0
CMS2_k127_5481342_2 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895,K01908 - 6.2.1.1,6.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 308.0
CMS2_k127_5481342_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 291.0
CMS2_k127_5481342_4 AIR carboxylase K01587 - 4.1.1.21,6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000004885 243.0
CMS2_k127_5481342_5 - - - - 0.000000000000000000000000000000000000000000009332 171.0
CMS2_k127_5481342_6 PFAM conserved - - - 0.000000000000000000000000000009605 124.0
CMS2_k127_5481342_7 small protein containing a coiled-coil domain - - - 0.0000000000000001959 81.0
CMS2_k127_5482722_0 Belongs to the GcvT family K00315 - 1.5.8.4 3.382e-242 762.0
CMS2_k127_5498093_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1102.0
CMS2_k127_5498093_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.375e-220 696.0
CMS2_k127_5498093_2 Acetyl propionyl-CoA carboxylase alpha subunit K01965 GO:0003674,GO:0003824,GO:0004658,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009374,GO:0009987,GO:0016421,GO:0016874,GO:0016885,GO:0017144,GO:0019752,GO:0019842,GO:0019899,GO:0031406,GO:0031974,GO:0032787,GO:0033218,GO:0033293,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0044237,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0070013,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901681 6.4.1.3 1.519e-212 670.0
CMS2_k127_5498093_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 576.0
CMS2_k127_5498093_4 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.000000000000000000000000000000000000005717 152.0
CMS2_k127_5498093_5 - - - - 0.000000000000000000000000000000005303 134.0
CMS2_k127_5498093_6 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000000000009582 111.0
CMS2_k127_5498093_7 SnoaL-like domain - - - 0.0000000000000719 78.0
CMS2_k127_55089_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 419.0
CMS2_k127_55089_1 Putative AphA-like transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000003478 190.0
CMS2_k127_55089_2 - - - - 0.00000000000000000000000000000000000000000000004923 171.0
CMS2_k127_55089_3 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000008523 140.0
CMS2_k127_55089_4 binds to the 23S rRNA K02939 - - 0.0000000000000000004134 90.0
CMS2_k127_5509463_0 Belongs to the DEAD box helicase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 540.0
CMS2_k127_5509463_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 367.0
CMS2_k127_5509463_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001033 270.0
CMS2_k127_5519889_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 7.303e-210 659.0
CMS2_k127_5519889_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 1.063e-196 619.0
CMS2_k127_5519889_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 591.0
CMS2_k127_5519889_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 467.0
CMS2_k127_5519889_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000001683 272.0
CMS2_k127_5519889_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000001894 265.0
CMS2_k127_5519889_6 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000007439 239.0
CMS2_k127_5519889_7 Domain of unknown function (DUF4115) K15539 - - 0.000000000000000000000000002059 122.0
CMS2_k127_5519889_8 Domain of unknown function (DUF4167) - - - 0.000000000000000000000001748 113.0
CMS2_k127_558119_0 COG2303 Choline dehydrogenase and related flavoproteins K00108 - 1.1.99.1 4.738e-227 729.0
CMS2_k127_558119_1 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 2.309e-199 629.0
CMS2_k127_558119_10 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000009176 162.0
CMS2_k127_558119_11 NnrS protein K07234 - - 0.000000000000000000000000000000001051 134.0
CMS2_k127_558119_12 Taurine catabolism dioxygenase TauD, TfdA family K03119 - 1.14.11.17 0.00000000000000000007857 92.0
CMS2_k127_558119_2 Polyamine ABC trasnporter, periplasmic polyamine-binding protein K02055,K11077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 583.0
CMS2_k127_558119_3 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 565.0
CMS2_k127_558119_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 512.0
CMS2_k127_558119_5 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 475.0
CMS2_k127_558119_6 hmm pf00528 K02053 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 396.0
CMS2_k127_558119_7 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 308.0
CMS2_k127_558119_8 Metal-binding integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002528 243.0
CMS2_k127_558119_9 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000001081 226.0
CMS2_k127_5592507_0 Phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 390.0
CMS2_k127_5592507_1 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000001505 223.0
CMS2_k127_5592507_2 cdp-diacylglycerol--glycerol-3-phosphate - - - 0.00000000000000000000000000000000000000000000000000000000000002787 222.0
CMS2_k127_5604699_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000001306 249.0
CMS2_k127_5604699_1 chorismate mutase - - - 0.0000000000000000000000000000000000000000000000000000000001027 213.0
CMS2_k127_5604699_2 Antibiotic biosynthesis monooxygenase K03824 - - 0.00000000000008637 76.0
CMS2_k127_5604839_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 489.0
CMS2_k127_5604839_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 424.0
CMS2_k127_5604839_2 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 326.0
CMS2_k127_5622445_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1214.0
CMS2_k127_5622445_1 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 434.0
CMS2_k127_5622445_2 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 390.0
CMS2_k127_5622445_3 Lysophospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002374 287.0
CMS2_k127_5622445_4 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000006961 246.0
CMS2_k127_5622445_5 SnoaL-like domain - - - 0.000000000000000000000000000000000000000001259 162.0
CMS2_k127_5622445_6 Zinc-finger domain - - - 0.00000000000002272 77.0
CMS2_k127_566292_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 2.448e-271 846.0
CMS2_k127_566292_1 Conserved region in glutamate synthase K22083 - 2.1.1.21 1.605e-252 782.0
CMS2_k127_566292_10 GXGXG motif K22082 - 2.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 304.0
CMS2_k127_566292_11 Transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003129 265.0
CMS2_k127_566292_12 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000000000000003242 249.0
CMS2_k127_566292_13 COG0655 Multimeric flavodoxin WrbA - - - 0.0000000000000000000000000000000000000000000000000000000000001941 215.0
CMS2_k127_566292_14 Thioesterase K07107 - - 0.0000000000000000000000000000000000000001709 156.0
CMS2_k127_566292_2 Orn/Lys/Arg decarboxylase, C-terminal domain K01584 - 4.1.1.19 3.842e-250 786.0
CMS2_k127_566292_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 3.975e-207 659.0
CMS2_k127_566292_4 Glutamine synthetase, catalytic domain K01915,K01949 - 6.3.1.2,6.3.4.12 1.949e-195 617.0
CMS2_k127_566292_5 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 525.0
CMS2_k127_566292_6 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 437.0
CMS2_k127_566292_7 Glutamine amidotransferase domain K22081 - 2.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 438.0
CMS2_k127_566292_8 Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 401.0
CMS2_k127_566292_9 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 364.0
CMS2_k127_5672935_0 Protein of unknown function - - - 1.504e-199 661.0
CMS2_k127_5672935_1 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 399.0
CMS2_k127_5672935_2 protein, possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000007968 130.0
CMS2_k127_5672935_3 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K14160 - - 0.000000000000000001368 95.0
CMS2_k127_5672935_4 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000179 60.0
CMS2_k127_5683517_0 Belongs to the GcvT family K00302 - 1.5.3.1 0.0 1092.0
CMS2_k127_5683517_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 3.565e-220 689.0
CMS2_k127_5683517_2 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 481.0
CMS2_k127_5683517_3 Sarcosine oxidase, delta subunit K00304 - 1.5.3.1 0.000000000000000000000000000000005262 140.0
CMS2_k127_5693199_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 447.0
CMS2_k127_5693199_1 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009669 270.0
CMS2_k127_5693199_10 Branched-chain amino acid transport - - - 0.000000000000003214 79.0
CMS2_k127_5693199_2 DinB family - - - 0.00000000000000000000000000000000000000000000000000000005224 201.0
CMS2_k127_5693199_3 AzlC protein - - - 0.00000000000000000000000000000000000000000000000000005887 195.0
CMS2_k127_5693199_4 Response regulator receiver - - - 0.000000000000000000000000000000000000000003121 163.0
CMS2_k127_5693199_5 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000005402 152.0
CMS2_k127_5693199_6 YGGT family K02221 - - 0.0000000000000000000000000009785 116.0
CMS2_k127_5693199_7 Histidine kinase - - - 0.00000000000000000000000646 104.0
CMS2_k127_5693199_9 Belongs to the UPF0235 family K09131 - - 0.00000000000000003975 89.0
CMS2_k127_570512_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.803e-200 629.0
CMS2_k127_570512_1 Protein conserved in bacteria K09991 - - 0.0004093 49.0
CMS2_k127_5724518_0 Permease MlaE K02066 - - 0.00000000000000000000000000000000008814 143.0
CMS2_k127_5724518_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000533 99.0
CMS2_k127_5728272_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 1.715e-204 641.0
CMS2_k127_5743765_0 NADH:flavin oxidoreductase / NADH oxidase family K00317 - 1.5.8.1,1.5.8.2 0.0 1177.0
CMS2_k127_5743765_1 Catalytic subunit of the nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC. Essential function for nitrate assimilation and may have a role in anaerobic metabolism K00380,K02567 - 1.8.1.2 0.0 1139.0
CMS2_k127_5743765_2 NapC/NirT cytochrome c family, N-terminal region K02569 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 345.0
CMS2_k127_5743765_3 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 317.0
CMS2_k127_5743765_4 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000000000000000000000000000000000232 189.0
CMS2_k127_5743765_5 - - - - 0.000000000000000000000000000000000000000000000000004032 186.0
CMS2_k127_5743765_6 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000007896 102.0
CMS2_k127_574855_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02034 - - 4.044e-288 911.0
CMS2_k127_574855_1 Amino acid kinase family K00928 - 2.7.2.4 1.617e-200 642.0
CMS2_k127_574855_10 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.000000000000000000000000000000000000000000000000000000000005134 210.0
CMS2_k127_574855_11 - - - - 0.0000000000000000000000000000000000000000000000000000005433 194.0
CMS2_k127_574855_13 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.00000000000000001528 82.0
CMS2_k127_574855_14 - - - - 0.0000000001333 68.0
CMS2_k127_574855_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 584.0
CMS2_k127_574855_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 518.0
CMS2_k127_574855_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 507.0
CMS2_k127_574855_5 Putative nucleotidyltransferase substrate binding domain K02342,K07182 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 503.0
CMS2_k127_574855_6 ATPases associated with a variety of cellular activities K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 409.0
CMS2_k127_574855_7 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005884 268.0
CMS2_k127_574855_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001482 238.0
CMS2_k127_574855_9 Acetyltransferase (GNAT) family K06718 - 2.3.1.178 0.0000000000000000000000000000000000000000000000000000000000002489 216.0
CMS2_k127_5754770_0 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 379.0
CMS2_k127_5754770_1 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000009406 255.0
CMS2_k127_5754770_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000168 216.0
CMS2_k127_5756867_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858,K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 548.0
CMS2_k127_5756867_1 Riboflavin synthase alpha chain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006983 277.0
CMS2_k127_5756867_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000001571 123.0
CMS2_k127_5756867_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000001136 85.0
CMS2_k127_5763801_0 malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 414.0
CMS2_k127_5763801_1 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000003057 185.0
CMS2_k127_5763801_2 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000004505 180.0
CMS2_k127_5763801_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000001745 171.0
CMS2_k127_5763801_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000001672 147.0
CMS2_k127_5764029_0 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 354.0
CMS2_k127_5764029_1 thioesterase' K07107 - - 0.0000000000000000000000000000000000775 138.0
CMS2_k127_5764029_2 Holliday junction DNA helicase ruvB C-terminus K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.0000000000000000000001775 97.0
CMS2_k127_5764029_3 Biopolymer transport protein K03559,K03560 - - 0.000000000000000003822 86.0
CMS2_k127_578257_0 - - - - 0.0000000000000000000000000000000000000000000000000001367 198.0
CMS2_k127_578257_1 acetyltransferase K03824 - - 0.00000000000000000000000000000005369 131.0
CMS2_k127_578794_0 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 554.0
CMS2_k127_578794_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 493.0
CMS2_k127_578794_2 FGGY family of carbohydrate kinases, C-terminal domain K00864 - 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000003456 262.0
CMS2_k127_579619_0 Domain of unknown function (DUF4175) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 415.0
CMS2_k127_579619_1 cell division K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 305.0
CMS2_k127_579619_2 Cell division protein K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002312 255.0
CMS2_k127_579619_3 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001515 228.0
CMS2_k127_579619_4 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000375 138.0
CMS2_k127_579619_5 Protein of unknown function (DUF3426) - - - 0.0000000000000000009418 97.0
CMS2_k127_5799980_0 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 312.0
CMS2_k127_5799980_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 302.0
CMS2_k127_5799980_2 Formate nitrite K06212 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001364 287.0
CMS2_k127_5799980_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000003876 182.0
CMS2_k127_5799980_4 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.00000000000000000000000000000004863 128.0
CMS2_k127_5820707_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001285 263.0
CMS2_k127_5820707_1 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000005083 253.0
CMS2_k127_5820707_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000001487 56.0
CMS2_k127_5824732_0 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000007976 116.0
CMS2_k127_5824732_1 protein conserved in bacteria - - - 0.000000000000009395 75.0
CMS2_k127_5830526_0 Branched-chain amino acid transport system / permease component K01998 - - 3.891e-214 676.0
CMS2_k127_5830526_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 567.0
CMS2_k127_5830526_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 546.0
CMS2_k127_5830526_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 425.0
CMS2_k127_5830526_4 Branched-chain amino acid ABC transporter ATPase K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 386.0
CMS2_k127_5868965_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006928 574.0
CMS2_k127_5868965_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000006574 132.0
CMS2_k127_5880476_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 526.0
CMS2_k127_5880476_1 N-formylglutamate amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001187 287.0
CMS2_k127_593407_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006489 527.0
CMS2_k127_593407_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 361.0
CMS2_k127_593407_2 AzlC protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001882 258.0
CMS2_k127_593407_3 Branched-chain amino acid transport protein (AzlD) - - - 0.0000000000000000000001218 111.0
CMS2_k127_5935076_0 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 1.397e-201 649.0
CMS2_k127_5935076_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 477.0
CMS2_k127_5935076_10 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000003418 229.0
CMS2_k127_5935076_11 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000006281 198.0
CMS2_k127_5935076_12 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000003362 186.0
CMS2_k127_5935076_13 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000001227 176.0
CMS2_k127_5935076_14 DNA repair protein MmcB-like - - - 0.000000000000000000000000000000000000000000001562 170.0
CMS2_k127_5935076_15 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000002307 164.0
CMS2_k127_5935076_16 Usg-like family - - - 0.00000000000000000000000000000001591 128.0
CMS2_k127_5935076_2 cobalamin synthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 411.0
CMS2_k127_5935076_3 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 413.0
CMS2_k127_5935076_4 His Kinase A (phosphoacceptor) domain K15011 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 383.0
CMS2_k127_5935076_5 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 331.0
CMS2_k127_5935076_6 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 317.0
CMS2_k127_5935076_7 Bacterial regulatory protein, Fis family K15012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002003 260.0
CMS2_k127_5935076_8 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006502 249.0
CMS2_k127_5935076_9 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000347 248.0
CMS2_k127_5944693_0 TIGRFAM ATP-dependent DNA helicase, RecQ K03654 - 3.6.4.12 3.469e-232 730.0
CMS2_k127_5944693_1 COG5265 ABC-type transport system involved in Fe-S cluster assembly permease and ATPase components K06147 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0006996,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009507,GO:0009526,GO:0009536,GO:0009555,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0010288,GO:0010380,GO:0016020,GO:0016043,GO:0018130,GO:0019222,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0019866,GO:0022622,GO:0030003,GO:0031090,GO:0031323,GO:0031326,GO:0031966,GO:0031967,GO:0031975,GO:0032501,GO:0032502,GO:0042221,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044429,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046686,GO:0046916,GO:0048229,GO:0048364,GO:0048731,GO:0048856,GO:0048878,GO:0050789,GO:0050790,GO:0050794,GO:0050801,GO:0050896,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051193,GO:0051276,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0065009,GO:0071704,GO:0071840,GO:0090056,GO:0090407,GO:0098771,GO:0099402,GO:1901360,GO:1901362,GO:1901401,GO:1901463,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000381 308.0
CMS2_k127_5956634_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.069e-197 628.0
CMS2_k127_5956634_1 ATPase (AAA K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 439.0
CMS2_k127_5956634_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 385.0
CMS2_k127_5956634_3 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003602 282.0
CMS2_k127_5956634_4 Preprotein translocase subunit YajC K03210 - - 0.0000000000000000000000000000000000006983 142.0
CMS2_k127_5956634_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000156 138.0
CMS2_k127_5956634_6 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000003221 116.0
CMS2_k127_5960583_0 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005738 267.0
CMS2_k127_5960583_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000005303 267.0
CMS2_k127_5960583_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000000000000000000000000000000000006674 162.0
CMS2_k127_5965359_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1252.0
CMS2_k127_5965359_1 Required for chromosome condensation and partitioning K03529 - - 0.0 1127.0
CMS2_k127_5965359_10 Protein of unknown function (DUF721) - - - 0.000000000003366 69.0
CMS2_k127_5965359_11 - - - - 0.00003771 48.0
CMS2_k127_5965359_2 Glycine cleavage T-protein C-terminal barrel domain K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 435.0
CMS2_k127_5965359_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 344.0
CMS2_k127_5965359_4 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000002829 214.0
CMS2_k127_5965359_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000002637 173.0
CMS2_k127_5965359_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000516 142.0
CMS2_k127_5965359_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000001181 135.0
CMS2_k127_5965359_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000007971 119.0
CMS2_k127_5965359_9 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000000000000000008093 90.0
CMS2_k127_5970960_0 Glycosyl hydrolases family 15 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 524.0
CMS2_k127_5970960_1 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000000000000000000003778 240.0
CMS2_k127_5973304_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 3.959e-291 904.0
CMS2_k127_5973304_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 557.0
CMS2_k127_5973304_2 Ornithine cyclodeaminase/mu-crystallin family K01750,K19743 - 1.5.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 322.0
CMS2_k127_5973304_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 315.0
CMS2_k127_5973304_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000001151 243.0
CMS2_k127_5973304_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000000513 166.0
CMS2_k127_5973304_6 Lipopolysaccharide assembly protein A domain - - - 0.0000000000000000305 86.0
CMS2_k127_5973304_7 Protein of unknown function (FYDLN_acid) - - - 0.00000000000005972 77.0
CMS2_k127_5987399_0 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 533.0
CMS2_k127_5987399_1 DNA helicase K03657 - 3.6.4.12 0.00000000000009496 72.0
CMS2_k127_5990290_0 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 314.0
CMS2_k127_5990290_1 Cytochrome c biogenesis protein K06196 - - 0.00000000000000000000000000000000000000000000000000000004458 200.0
CMS2_k127_5990290_2 Haem-degrading - - - 0.000000000000000000000000000000000000000000008172 175.0
CMS2_k127_5990290_3 - K09004 - - 0.0000000000000000000000000000000000000000001632 163.0
CMS2_k127_5990290_4 Regulatory protein SoxS - - - 0.00000000000000000000000000000000003353 139.0
CMS2_k127_5990290_5 Bacterial regulatory protein, arsR family - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000004446 125.0
CMS2_k127_6_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 432.0
CMS2_k127_6_1 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 302.0
CMS2_k127_6_2 Predicted membrane protein (DUF2142) - - - 0.00000000000864 78.0
CMS2_k127_6011965_0 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 346.0
CMS2_k127_6011965_1 Phytoene synthase K21678 - 2.5.1.103 0.00000000000000000000000000000000000000000000000000000000000000000001294 245.0
CMS2_k127_6011965_2 Squalene/phytoene synthase K21678,K21679 - 2.5.1.103,4.2.3.156 0.0000000000000000000000000000001192 127.0
CMS2_k127_6011965_3 protein conserved in bacteria K09796 - - 0.000000000000000000001119 97.0
CMS2_k127_6018112_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.341e-283 876.0
CMS2_k127_6018112_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000004927 49.0
CMS2_k127_6036414_0 cation transport ATPase - - - 5.672e-195 629.0
CMS2_k127_6065150_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate K00108 - 1.1.99.1 3.699e-290 899.0
CMS2_k127_6065150_1 Phosphoenolpyruvate carboxylase K01595 - 4.1.1.31 0.0000003194 55.0
CMS2_k127_6081355_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.065e-196 618.0
CMS2_k127_6081355_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 342.0
CMS2_k127_6081355_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 305.0
CMS2_k127_6081355_3 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000001029 221.0
CMS2_k127_6081355_4 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.00000000000000000000000000005347 133.0
CMS2_k127_608772_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K22209 - 4.2.1.81 2.987e-235 729.0
CMS2_k127_608772_1 TRAP-type C4-dicarboxylate transport system, large permease component - - - 5.561e-205 644.0
CMS2_k127_608772_10 - - - - 0.0000000000001108 77.0
CMS2_k127_608772_2 Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 500.0
CMS2_k127_608772_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 470.0
CMS2_k127_608772_4 Belongs to the LDH2 MDH2 oxidoreductase family K00073 GO:0000255,GO:0000256,GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009040,GO:0009056,GO:0009442,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0034641,GO:0042737,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0046483,GO:0046700,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.1.1.350 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 380.0
CMS2_k127_608772_5 C-terminal domain of 1-Cys peroxiredoxin - GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0010035,GO:0010038,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0046686,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 367.0
CMS2_k127_608772_6 Transcriptional regulator, LysR family K21645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 290.0
CMS2_k127_608772_7 Acts on guanine, xanthine and to a lesser extent hypoxanthine K00769 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000000000000002051 248.0
CMS2_k127_608772_8 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.000000000000000000000000000000000000000000000000001033 189.0
CMS2_k127_608772_9 PFAM D-galactarate dehydratase Altronate hydrolase, C terminus K01685 - 4.2.1.7 0.00000000000000003556 81.0
CMS2_k127_6107574_0 Thioredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001765 243.0
CMS2_k127_6107574_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000006742 174.0
CMS2_k127_6107574_2 oxidation protein K17227 - - 0.00000000000000000000000000000000000000000000003795 171.0
CMS2_k127_6107574_3 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000001427 171.0
CMS2_k127_6107574_4 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000002157 164.0
CMS2_k127_6107574_5 - - - - 0.000000000001013 78.0
CMS2_k127_6119759_0 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 353.0
CMS2_k127_6119759_1 CHASE2 K01768 - 4.6.1.1 0.000000000006074 68.0
CMS2_k127_6122403_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 342.0
CMS2_k127_6122403_1 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 313.0
CMS2_k127_6122403_2 Cupin superfamily K09705 - - 0.0000000000000000000000000000000000000000000000000009529 191.0
CMS2_k127_6122403_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000002097 57.0
CMS2_k127_6124500_0 ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000284 255.0
CMS2_k127_6124500_1 Adenylosuccinate lyase C-terminus K01756,K01857 - 4.3.2.2,5.5.1.2 0.0000000000000000000000000000000000000000000000007619 179.0
CMS2_k127_6124500_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000001391 101.0
CMS2_k127_6150501_0 bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.087e-227 717.0
CMS2_k127_6150501_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 481.0
CMS2_k127_6150501_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 372.0
CMS2_k127_6150501_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004261 279.0
CMS2_k127_6150501_4 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006418 276.0
CMS2_k127_6150501_5 COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase UDP-N-acetylglucosamine-1-phosphate transferase K02851,K13007 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007009 277.0
CMS2_k127_6150501_6 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000419 278.0
CMS2_k127_6150501_7 periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000000000000000000001426 192.0
CMS2_k127_6150501_8 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000006919 128.0
CMS2_k127_6150501_9 Major facilitator superfamily K06902 - - 0.0000000000000000000000000000005829 124.0
CMS2_k127_6165598_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 4.496e-244 771.0
CMS2_k127_6165598_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 549.0
CMS2_k127_6165598_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 416.0
CMS2_k127_6165598_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000000000000000000000001066 237.0
CMS2_k127_6165598_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000001292 149.0
CMS2_k127_6165598_5 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000002249 146.0
CMS2_k127_6165598_6 - - - - 0.00000000000000000000000000000000006531 142.0
CMS2_k127_6168969_0 ATP dependent DNA ligase C terminal region K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.403e-242 758.0
CMS2_k127_6168969_1 ATPases associated with a variety of cellular activities K02000 GO:0000166,GO:0003674,GO:0004888,GO:0005034,GO:0005215,GO:0005275,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006950,GO:0006970,GO:0006972,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0009628,GO:0009987,GO:0015695,GO:0015696,GO:0015697,GO:0015837,GO:0015838,GO:0016020,GO:0016021,GO:0017076,GO:0022857,GO:0023052,GO:0030554,GO:0031224,GO:0031460,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0038023,GO:0043167,GO:0043168,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0060089,GO:0065007,GO:0071702,GO:0071705,GO:0071944,GO:0072337,GO:0097159,GO:0097367,GO:0098533,GO:0098796,GO:0098797,GO:1901265,GO:1901363,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005007 465.0
CMS2_k127_6168969_2 Choline ABC transporter periplasmic binding protein K02002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 423.0
CMS2_k127_6168969_3 Binding-protein-dependent transport system inner membrane component K02001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 415.0
CMS2_k127_6168969_4 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 310.0
CMS2_k127_6168969_5 dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000007021 222.0
CMS2_k127_6168969_6 Subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000002195 185.0
CMS2_k127_6168969_7 dioxygenase activity - - - 0.0000000001101 64.0
CMS2_k127_6171158_0 ABC-type branched-chain amino acid transport systems periplasmic component K01999,K11959 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 421.0
CMS2_k127_6171158_1 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 390.0
CMS2_k127_6171158_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 308.0
CMS2_k127_6171158_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002555 288.0
CMS2_k127_6171158_4 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002337 264.0
CMS2_k127_6171158_5 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001988 256.0
CMS2_k127_6171158_6 Belongs to the enoyl-CoA hydratase isomerase family K01715,K16880 - 4.2.1.17 0.000000000000000000000000000000007673 137.0
CMS2_k127_6180514_0 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 522.0
CMS2_k127_6180514_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 366.0
CMS2_k127_6180514_10 - - - - 0.0000000000000000003745 98.0
CMS2_k127_6180514_11 Aminoacyl-tRNA editing domain - - - 0.0000000000000106 79.0
CMS2_k127_6180514_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 362.0
CMS2_k127_6180514_3 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 336.0
CMS2_k127_6180514_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 320.0
CMS2_k127_6180514_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000001474 234.0
CMS2_k127_6180514_6 Putative bacterial sensory transduction regulator - - - 0.000000000000000000000000000000000000000000000000000000000001409 213.0
CMS2_k127_6180514_7 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000003613 142.0
CMS2_k127_6180514_8 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000283 131.0
CMS2_k127_6180514_9 Membrane fusogenic activity K09806 - - 0.0000000000000000000004301 106.0
CMS2_k127_620126_0 Zn-dependent proteases and their inactivated homologs K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 516.0
CMS2_k127_620126_1 Belongs to the UbiD family K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 421.0
CMS2_k127_6205509_0 Protein of unknown function (DUF521) K09123 - - 4.796e-250 783.0
CMS2_k127_6205509_1 Dihydrodipicolinate synthetase family K21062 - 3.5.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 511.0
CMS2_k127_6205509_2 Amino acid ABC transporter substrate-binding protein K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 469.0
CMS2_k127_6205509_3 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 411.0
CMS2_k127_6205509_4 ABC-type amino acid transport system permease component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 363.0
CMS2_k127_6205509_5 ABC-type amino acid transport system permease component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 357.0
CMS2_k127_6205509_6 Transcriptional regulator, gntR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 305.0
CMS2_k127_6213430_0 glutamine synthetase K01915 - 6.3.1.2 4.304e-226 707.0
CMS2_k127_6213430_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 476.0
CMS2_k127_6213430_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 356.0
CMS2_k127_6213430_3 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000111 224.0
CMS2_k127_6213430_4 PFAM ABC-2 type transporter K01992,K09690 - - 0.000000000000000000000000000000655 132.0
CMS2_k127_6213430_5 ABC-type polysaccharide polyol phosphate transport system ATPase - - - 0.000000000000000113 91.0
CMS2_k127_621712_0 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 422.0
CMS2_k127_621712_1 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 319.0
CMS2_k127_621712_2 Belongs to the SfsA family K06206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002571 281.0
CMS2_k127_621712_3 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.000000000000000000000000000000000000000000000000000000000000000131 225.0
CMS2_k127_621712_4 membrane protein involved in D-alanine export - - - 0.000000000000000005534 86.0
CMS2_k127_6227060_0 Formate dehydrogenase subunit alpha - - - 0.0 1090.0
CMS2_k127_6227060_1 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 431.0
CMS2_k127_628406_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 8.658e-252 782.0
CMS2_k127_628406_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007406 284.0
CMS2_k127_628406_2 transcription regulator, contains HTH domain (MarR family) - - - 0.00000000000000000000000000000000000000000000000000000005605 213.0
CMS2_k127_6287072_0 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 497.0
CMS2_k127_6287072_1 COG0534 Na -driven multidrug efflux pump K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 462.0
CMS2_k127_6287072_2 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000003995 200.0
CMS2_k127_6287072_3 - - - - 0.0000000000000004536 85.0
CMS2_k127_6287072_4 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000001371 77.0
CMS2_k127_6308117_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.065e-198 627.0
CMS2_k127_6308117_1 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 346.0
CMS2_k127_6316267_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 5.367e-198 627.0
CMS2_k127_6316267_1 TonB-dependent Receptor Plug Domain K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 550.0
CMS2_k127_6316267_10 COG2346, Truncated hemoglobins K03406,K06886 GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008941,GO:0009056,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016491,GO:0016705,GO:0016708,GO:0017144,GO:0019825,GO:0020012,GO:0020037,GO:0030682,GO:0034641,GO:0036094,GO:0042133,GO:0042135,GO:0042221,GO:0042737,GO:0043207,GO:0044237,GO:0044248,GO:0044270,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046209,GO:0046210,GO:0046906,GO:0048037,GO:0050896,GO:0051213,GO:0051410,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0072593,GO:0075136,GO:0097159,GO:0098754,GO:1901363,GO:1901698,GO:2001057 - 0.0000000000000000000000000000001401 128.0
CMS2_k127_6316267_11 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000001534 105.0
CMS2_k127_6316267_2 Peptidase family M20/M25/M40 K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 496.0
CMS2_k127_6316267_3 Amidinotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 402.0
CMS2_k127_6316267_4 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 376.0
CMS2_k127_6316267_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 359.0
CMS2_k127_6316267_6 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 284.0
CMS2_k127_6316267_7 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006701 276.0
CMS2_k127_6316267_8 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000119 264.0
CMS2_k127_6316267_9 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000000000000000000009864 222.0
CMS2_k127_6317434_0 Bacterial protein of unknown function (DUF853) K06915 - - 4.262e-201 638.0
CMS2_k127_6317434_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 483.0
CMS2_k127_6317434_10 Methyltransferase domain - - - 0.00000000001245 66.0
CMS2_k127_6317434_2 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 294.0
CMS2_k127_6317434_3 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004682 252.0
CMS2_k127_6317434_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000000000001181 218.0
CMS2_k127_6317434_5 protein conserved in bacteria K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000001303 213.0
CMS2_k127_6317434_6 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000001273 207.0
CMS2_k127_6317434_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000000001254 197.0
CMS2_k127_6317434_8 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.000000000000000000000000000000000000000000000000002767 188.0
CMS2_k127_6317434_9 PQ loop repeat K15383 - - 0.00000000000000000000026 100.0
CMS2_k127_6321874_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.433e-224 703.0
CMS2_k127_6321874_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 478.0
CMS2_k127_6321874_10 - - - - 0.0000000000000000000000000001805 117.0
CMS2_k127_6321874_11 Uncharacterized ACR, COG1399 - - - 0.000000000000000000000000000388 121.0
CMS2_k127_6321874_12 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000007549 101.0
CMS2_k127_6321874_13 - - - - 0.000000343 53.0
CMS2_k127_6321874_2 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 480.0
CMS2_k127_6321874_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 466.0
CMS2_k127_6321874_4 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 469.0
CMS2_k127_6321874_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001262 274.0
CMS2_k127_6321874_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000000001295 164.0
CMS2_k127_6321874_7 Ubiquinol-cytochrome C chaperone K17662 - - 0.00000000000000000000000000000000000000000003404 167.0
CMS2_k127_6321874_8 transcriptional regulator, MerR - - - 0.00000000000000000000000000000000000001271 149.0
CMS2_k127_6321874_9 Small protein A (tmRNA-binding) - - - 0.000000000000000000000000000000004024 136.0
CMS2_k127_6325066_0 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000518 262.0
CMS2_k127_6326936_0 COG1702 Phosphate starvation-inducible protein PhoH K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 440.0
CMS2_k127_6326936_1 COG1253 Hemolysins and related proteins containing CBS domains K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 356.0
CMS2_k127_6326936_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000004217 220.0
CMS2_k127_6326936_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000006372 173.0
CMS2_k127_6326936_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000006141 157.0
CMS2_k127_6331532_0 peptidase M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 435.0
CMS2_k127_6331532_2 Methyltransferase FkbM domain - - - 0.0009174 44.0
CMS2_k127_6349171_0 COG0303 Molybdopterin biosynthesis enzyme K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007119 495.0
CMS2_k127_6349171_1 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005809 249.0
CMS2_k127_6349171_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000001705 186.0
CMS2_k127_6349171_3 COG0314 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.00000000000000000000000000000466 120.0
CMS2_k127_6349171_4 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000000000000000000354 119.0
CMS2_k127_6349171_5 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000003659 90.0
CMS2_k127_6383901_0 FtsX-like permease family K02004 - - 6.623e-284 904.0
CMS2_k127_6383901_1 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 463.0
CMS2_k127_6383901_2 HlyD family secretion protein K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 456.0
CMS2_k127_6383901_3 ATPases associated with a variety of cellular activities K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 359.0
CMS2_k127_6383901_4 Ankyrin repeats (3 copies) K06867,K21440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009989 254.0
CMS2_k127_6391851_0 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 382.0
CMS2_k127_6391851_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000002989 206.0
CMS2_k127_6391851_2 transcriptional regulator - - - 0.0000000000000001237 80.0
CMS2_k127_6393091_0 sugar phosphatases of the HAD superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 301.0
CMS2_k127_6393091_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000001592 134.0
CMS2_k127_6393091_2 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01847 - 5.4.99.2 0.00000000000000000000000000000001347 127.0
CMS2_k127_6402462_0 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 482.0
CMS2_k127_6402462_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 471.0
CMS2_k127_6402462_2 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009778 422.0
CMS2_k127_6402462_3 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 351.0
CMS2_k127_6402462_4 COG2771 DNA-binding HTH domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000000000002984 216.0
CMS2_k127_6402462_5 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000001112 166.0
CMS2_k127_6402462_6 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000001405 169.0
CMS2_k127_6402638_0 NADH:flavin oxidoreductase / NADH oxidase family K21833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 407.0
CMS2_k127_6402638_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000009002 121.0
CMS2_k127_6402638_2 - - - - 0.000000000000000000001394 97.0
CMS2_k127_6402638_3 Predicted membrane protein (DUF2061) - - - 0.00000000000000000001614 93.0
CMS2_k127_6422223_0 oligoendopeptidase F K08602 - - 2.662e-272 850.0
CMS2_k127_6422223_1 AMP-binding enzyme K01897 - 6.2.1.3 4.674e-235 743.0
CMS2_k127_6422223_2 Rieske 2Fe-2S domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 410.0
CMS2_k127_6422223_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 327.0
CMS2_k127_6422223_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001334 270.0
CMS2_k127_6422223_5 Protein of unknown function (DUF3137) - - - 0.00000000000000000000000000000000000000000001188 174.0
CMS2_k127_6422223_6 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000000001033 138.0
CMS2_k127_6422223_7 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000001285 138.0
CMS2_k127_6422223_8 Protein of unknown function (DUF3429) - - - 0.000000000000000000000002673 109.0
CMS2_k127_6422223_9 LemA family K03744 - - 0.000000000000000000001995 94.0
CMS2_k127_6450296_0 COG2873 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 2.22e-227 711.0
CMS2_k127_6450296_1 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 584.0
CMS2_k127_6450296_2 Enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 404.0
CMS2_k127_6450296_3 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 377.0
CMS2_k127_6450296_4 effector of murein hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 333.0
CMS2_k127_6450296_5 COG1846 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000006033 171.0
CMS2_k127_6450296_6 effector of murein hydrolase LrgA K06518 - - 0.0000000000000000000000000000000000000009193 151.0
CMS2_k127_6450296_7 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 0.0000000000000000000000003384 104.0
CMS2_k127_6450296_8 Helix-turn-helix domain - - - 0.0000000000000000000000007207 108.0
CMS2_k127_6451836_0 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002006 283.0
CMS2_k127_6451836_1 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006128 295.0
CMS2_k127_6451836_2 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008912 254.0
CMS2_k127_6451836_3 Peptidase propeptide and YPEB domain - - - 0.00000000000000000000102 103.0
CMS2_k127_6451836_4 PFAM GGDEF domain containing protein - - - 0.000000000000005166 83.0
CMS2_k127_6456491_0 Pyrimidine nucleoside phosphorylase C-terminal domain K00758 - 2.4.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 510.0
CMS2_k127_6456491_1 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 312.0
CMS2_k127_6456491_2 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001806 289.0
CMS2_k127_6456491_3 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000885 201.0
CMS2_k127_6456491_4 Cytochrome P460 - - - 0.0000000000000000000000000000000000000000000001572 181.0
CMS2_k127_6456491_5 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000000000004961 154.0
CMS2_k127_6456491_6 Belongs to the DEAD box helicase family - - - 0.0004295 47.0
CMS2_k127_6469601_0 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 559.0
CMS2_k127_6469601_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 461.0
CMS2_k127_6490443_0 Arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 518.0
CMS2_k127_6490443_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000006818 198.0
CMS2_k127_6490443_2 Glutathione S-transferase, N-terminal domain - - - 0.000000000000000000000000000000000000000007407 162.0
CMS2_k127_6490443_3 - - - - 0.000000000000000000000000000000002947 138.0
CMS2_k127_6490443_4 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000009829 131.0
CMS2_k127_6499474_0 Catalyzes the formation of succinate from succinate semialdehyde K00135 GO:0000166,GO:0001505,GO:0003674,GO:0003824,GO:0004777,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006105,GO:0006520,GO:0006536,GO:0006538,GO:0006540,GO:0006807,GO:0008150,GO:0008152,GO:0009013,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009448,GO:0009450,GO:0009987,GO:0016054,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0019752,GO:0032787,GO:0036094,GO:0042133,GO:0042135,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.2.1.16,1.2.1.20,1.2.1.79 2.397e-254 790.0
CMS2_k127_6499474_1 FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 524.0
CMS2_k127_6499474_2 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 474.0
CMS2_k127_6499474_3 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 450.0
CMS2_k127_6499474_4 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000009157 218.0
CMS2_k127_6499474_5 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000003785 144.0
CMS2_k127_6499474_6 Glycosyltransferase family 17 K00737 - 2.4.1.144 0.00000000000002512 86.0
CMS2_k127_6499474_7 glycosyl transferase family 2 K20444 - - 0.000009967 58.0
CMS2_k127_6502060_0 This protein is involved in the repair of mismatches in DNA K03555 - - 0.0 1168.0
CMS2_k127_6502060_1 malic enzyme K00029 - 1.1.1.40 0.0 1122.0
CMS2_k127_6502060_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0006355,GO:0006464,GO:0006807,GO:0006808,GO:0007154,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009719,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0018175,GO:0018177,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060255,GO:0065007,GO:0070887,GO:0071310,GO:0071417,GO:0071495,GO:0071496,GO:0071704,GO:0080090,GO:0090293,GO:1901564,GO:1901698,GO:1901699,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 2.7.7.59 0.0 1030.0
CMS2_k127_6502060_3 signal transduction histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 433.0
CMS2_k127_6502060_4 COG0226 ABC-type phosphate transport system, periplasmic component K02040 - - 0.00000000000000000000000000000000000004221 147.0
CMS2_k127_654999_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.285e-292 904.0
CMS2_k127_654999_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 2.27e-231 724.0
CMS2_k127_654999_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 568.0
CMS2_k127_654999_3 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 442.0
CMS2_k127_654999_4 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 366.0
CMS2_k127_654999_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 307.0
CMS2_k127_654999_6 Preprotein translocase SecG subunit K03075 - - 0.000000000000000007667 87.0
CMS2_k127_6554763_0 Aconitase family (aconitate hydratase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 582.0
CMS2_k127_6554763_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001477 249.0
CMS2_k127_6554763_2 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000004167 227.0
CMS2_k127_6554763_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000007951 215.0
CMS2_k127_6554763_4 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000002234 165.0
CMS2_k127_6554763_5 Acetyltransferase (GNAT) domain - - - 0.0000000000000006306 82.0
CMS2_k127_6564625_0 COG0480 Translation elongation factors (GTPases) K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 500.0
CMS2_k127_6564625_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 485.0
CMS2_k127_6564625_2 2-keto-4-pentenoate hydratase K02554 - 4.2.1.80 0.00000000000000000000000000000000000000000000000242 183.0
CMS2_k127_6564625_3 Pentapeptide repeats (9 copies) - - - 0.0000000000000000000000000000000000000000006795 166.0
CMS2_k127_6564625_4 - - - - 0.000000000000000001448 96.0
CMS2_k127_6565690_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 9.214e-219 693.0
CMS2_k127_6565690_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 463.0
CMS2_k127_6565690_2 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009535 389.0
CMS2_k127_6565690_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003882 276.0
CMS2_k127_6565690_4 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004664 264.0
CMS2_k127_6565690_5 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000008733 201.0
CMS2_k127_6565690_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000009383 178.0
CMS2_k127_6565690_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000000000000000348 133.0
CMS2_k127_6565690_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000004407 113.0
CMS2_k127_6565690_9 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000007679 76.0
CMS2_k127_6567808_0 PFAM Citrate transporter - - - 2.419e-212 672.0
CMS2_k127_6567808_1 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 507.0
CMS2_k127_6567808_2 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 317.0
CMS2_k127_6567808_3 Binding-protein-dependent transport system inner membrane component K02050,K15554,K15599 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 305.0
CMS2_k127_6567808_4 ABC transporter K15600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001631 274.0
CMS2_k127_6567808_5 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000008385 262.0
CMS2_k127_6567808_6 Carbon monoxide dehydrogenase subunit G (CoxG) K09386 - - 0.0000000000000000000000000000000000000000000000000000000000000000001536 243.0
CMS2_k127_6567808_7 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000241 172.0
CMS2_k127_6567808_8 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0000000000000000000000000006105 114.0
CMS2_k127_6570737_0 Long-chain fatty acid--CoA ligase K01897 - 6.2.1.3 4.659e-296 920.0
CMS2_k127_6570737_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 2.324e-200 634.0
CMS2_k127_6570737_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 562.0
CMS2_k127_6570737_3 ABC transporter ATP-binding protein K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 468.0
CMS2_k127_6570737_4 Branched-chain amino acid ABC transporter, ATP-binding protein K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 433.0
CMS2_k127_6570737_5 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 424.0
CMS2_k127_6570737_6 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000001454 150.0
CMS2_k127_6570737_8 AntiSigma factor - - - 0.0005209 50.0
CMS2_k127_6573019_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 396.0
CMS2_k127_6573019_1 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000006302 263.0
CMS2_k127_6573019_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000195 238.0
CMS2_k127_6573019_3 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000002921 184.0
CMS2_k127_659625_0 His Kinase A (phosphoacceptor) domain - - - 4.881e-302 955.0
CMS2_k127_659625_1 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002953 275.0
CMS2_k127_659625_3 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000008758 48.0
CMS2_k127_6601662_0 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 392.0
CMS2_k127_6601662_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000006347 222.0
CMS2_k127_6601662_2 Protein of unknown function (DUF952) - - - 0.0000000000000000000000000000000000000000000004334 171.0
CMS2_k127_6611118_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1585.0
CMS2_k127_6611118_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1244.0
CMS2_k127_6611118_2 Adenylate cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000007812 272.0
CMS2_k127_6611118_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000441 247.0
CMS2_k127_6611118_4 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000007659 236.0
CMS2_k127_6611118_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000000000000003236 227.0
CMS2_k127_6611118_6 Acetyltransferase (GNAT) domain K02348 - - 0.0000000000000000000000000000008555 126.0
CMS2_k127_6627840_0 Rieske 2Fe-2S K00479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 452.0
CMS2_k127_6627840_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 342.0
CMS2_k127_6627840_2 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000001348 220.0
CMS2_k127_6627840_3 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000006454 209.0
CMS2_k127_6628029_0 DNA polymerase K02337 - 2.7.7.7 6.805e-265 827.0
CMS2_k127_6628029_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 7.955e-224 700.0
CMS2_k127_6628029_2 COG4591 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 497.0
CMS2_k127_6628029_3 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006177 283.0
CMS2_k127_6638445_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.302e-218 683.0
CMS2_k127_6638445_1 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 438.0
CMS2_k127_6638445_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 308.0
CMS2_k127_6638445_3 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 309.0
CMS2_k127_6638481_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1350.0
CMS2_k127_6638481_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.497e-283 886.0
CMS2_k127_6638481_10 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000007278 165.0
CMS2_k127_6638481_11 Protein of unknown function (DUF3035) - - - 0.00000000000000000000000000000000000000000009673 167.0
CMS2_k127_6638481_12 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000002837 154.0
CMS2_k127_6638481_13 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000002989 101.0
CMS2_k127_6638481_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 6.568e-271 845.0
CMS2_k127_6638481_3 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 526.0
CMS2_k127_6638481_4 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 518.0
CMS2_k127_6638481_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 441.0
CMS2_k127_6638481_6 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 395.0
CMS2_k127_6638481_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 336.0
CMS2_k127_6638481_8 Glycosyl transferase group 2 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001786 232.0
CMS2_k127_6638481_9 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000001162 204.0
CMS2_k127_6657730_0 Belongs to the isocitrate and isopropylmalate dehydrogenases family K00031 - 1.1.1.42 8.772e-234 733.0
CMS2_k127_6657730_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 297.0
CMS2_k127_6657730_2 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002719 244.0
CMS2_k127_6657730_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K09565 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000184 231.0
CMS2_k127_6657730_4 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000002993 219.0
CMS2_k127_6669377_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.162e-216 692.0
CMS2_k127_6669377_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000002109 241.0
CMS2_k127_6669377_2 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000002074 196.0
CMS2_k127_6671_0 Uncharacterized protein family (UPF0051) K09014 - - 4.261e-284 876.0
CMS2_k127_6671_1 Cysteine desulfurase K11717 GO:0001887,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009000,GO:0009507,GO:0009536,GO:0009987,GO:0010035,GO:0010269,GO:0016043,GO:0016226,GO:0016740,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018282,GO:0018283,GO:0019538,GO:0022607,GO:0031071,GO:0031163,GO:0036211,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071704,GO:0071840,GO:1901564 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 508.0
CMS2_k127_6671_2 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 401.0
CMS2_k127_6671_3 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 343.0
CMS2_k127_6671_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000002947 171.0
CMS2_k127_6671_5 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000001731 161.0
CMS2_k127_6671_6 Cytochrome c2 K08738 - - 0.0000000000000000000000000000000006663 134.0
CMS2_k127_6693180_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 391.0
CMS2_k127_6693180_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 362.0
CMS2_k127_6693180_2 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000003176 246.0
CMS2_k127_6693180_3 Cell division protein FtsQ K03589 - - 0.000000000000000000000000000000000000000000000000000000000001688 232.0
CMS2_k127_6726501_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 342.0
CMS2_k127_6726501_1 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000002775 231.0
CMS2_k127_6726501_2 Belongs to the universal stress protein A family - - - 0.00000000000000000000000642 108.0
CMS2_k127_6727246_0 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 380.0
CMS2_k127_6727246_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008674 286.0
CMS2_k127_673140_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 501.0
CMS2_k127_673140_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 338.0
CMS2_k127_673140_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 305.0
CMS2_k127_673140_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000003439 84.0
CMS2_k127_6735265_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 1.642e-220 692.0
CMS2_k127_6735265_1 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000002219 201.0
CMS2_k127_6758876_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 498.0
CMS2_k127_6758876_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 347.0
CMS2_k127_6758876_10 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000001231 95.0
CMS2_k127_6758876_2 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 333.0
CMS2_k127_6758876_3 COG0694 Thioredoxin-like proteins and domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 282.0
CMS2_k127_6758876_4 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001057 248.0
CMS2_k127_6758876_5 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000001398 220.0
CMS2_k127_6758876_6 ROS/MUCR transcriptional regulator protein - - - 0.0000000000000000000000000000000000000000000000000000000002857 205.0
CMS2_k127_6758876_7 COG1214 Inactive homolog of metal-dependent proteases K14742 - - 0.0000000000000000000000000000000000000000000000000000000003021 209.0
CMS2_k127_6758876_8 universal stress protein UspA and related nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000005298 200.0
CMS2_k127_6758876_9 Putative transmembrane protein (Alph_Pro_TM) - - - 0.0000000000000000000000000000000002059 135.0
CMS2_k127_6785993_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 515.0
CMS2_k127_6785993_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 457.0
CMS2_k127_6785993_2 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 320.0
CMS2_k127_6785993_3 Staphylococcal nuclease homologue - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001292 275.0
CMS2_k127_6785993_4 transcriptional regulator K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001428 250.0
CMS2_k127_6785993_5 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000001118 211.0
CMS2_k127_6785993_6 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000000000000000000000000001808 139.0
CMS2_k127_6785993_7 Tellurite resistance protein TerB - - - 0.0000000000000000000000000141 110.0
CMS2_k127_6794580_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 6.064e-285 881.0
CMS2_k127_6794580_1 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 591.0
CMS2_k127_6794580_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 368.0
CMS2_k127_6794580_3 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain K21826 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 369.0
CMS2_k127_6794580_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002786 273.0
CMS2_k127_6794580_5 COG1145 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002986 270.0
CMS2_k127_6794580_6 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000006083 224.0
CMS2_k127_6794580_7 2-hydroxychromene-2-carboxylate isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000002223 219.0
CMS2_k127_6806179_0 Thiol disulfide interchange protein K04084,K08344 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 430.0
CMS2_k127_6806179_1 Redoxin K03386 - 1.11.1.15 0.0000000000000000000002408 106.0
CMS2_k127_681078_0 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 459.0
CMS2_k127_681078_1 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000001681 131.0
CMS2_k127_6820828_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 6.827e-222 694.0
CMS2_k127_6820828_1 RNA polymerase sigma factor K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 472.0
CMS2_k127_6820828_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 383.0
CMS2_k127_6820828_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 374.0
CMS2_k127_6820828_4 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 373.0
CMS2_k127_6820828_5 Paraquat-inducible protein A K03808 - - 0.0000000000000000000000000000005864 129.0
CMS2_k127_6835918_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1150.0
CMS2_k127_6835918_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 539.0
CMS2_k127_6835918_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 338.0
CMS2_k127_6835918_3 5'-nucleotidase, C-terminal domain K01081,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 313.0
CMS2_k127_6835918_4 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007084 286.0
CMS2_k127_6835918_5 3-oxoadipate enol-lactonase - - - 0.0000000000000000000000000000000000000000000000000000001538 204.0
CMS2_k127_6835918_6 - - - - 0.000000000000001447 91.0
CMS2_k127_6835918_7 PFAM transglutaminase family protein cysteine peptidase BTLCP - - - 0.0000000000009229 76.0
CMS2_k127_6835918_8 Sporulation related domain - - - 0.000000000002598 80.0
CMS2_k127_6835918_9 Outer membrane autotransporter - - - 0.00000397 49.0
CMS2_k127_6886615_0 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 4.529e-219 688.0
CMS2_k127_6886615_1 Cell Wall Hydrolase - - - 0.0000000000000000000000000000000000000000000000000009837 187.0
CMS2_k127_6886615_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000147 174.0
CMS2_k127_690751_0 UDP-glucoronosyl and UDP-glucosyl transferase - - - 1.091e-212 670.0
CMS2_k127_690751_1 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 509.0
CMS2_k127_690751_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 436.0
CMS2_k127_690751_3 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 416.0
CMS2_k127_690751_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 365.0
CMS2_k127_690751_5 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000005852 243.0
CMS2_k127_690751_6 Protein of unknown function (DUF861) K06995 - - 0.00000000000000000000000000000000000000000000000000000000000001316 216.0
CMS2_k127_690751_7 Aldehyde dehydrogenase family - - - 0.0000000000000000008849 89.0
CMS2_k127_6909292_0 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 417.0
CMS2_k127_6909292_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 298.0
CMS2_k127_6909292_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000423 176.0
CMS2_k127_6910836_0 COG1960 Acyl-CoA dehydrogenases K14448 - 1.3.8.12 1.952e-267 832.0
CMS2_k127_6910836_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001,K14446 - 1.1.1.1,1.3.1.85 2.7e-205 640.0
CMS2_k127_6915739_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 594.0
CMS2_k127_6915739_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008338 302.0
CMS2_k127_6915739_2 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000002514 205.0
CMS2_k127_6915739_3 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000001382 153.0
CMS2_k127_6915739_4 protein conserved in bacteria - - - 0.000000000000000000000000000000001567 140.0
CMS2_k127_6921684_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 436.0
CMS2_k127_6921684_1 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 311.0
CMS2_k127_6946666_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 471.0
CMS2_k127_6946666_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 342.0
CMS2_k127_6946666_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000478 214.0
CMS2_k127_6946666_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000001525 184.0
CMS2_k127_6981186_0 ABC-type multidrug transport system, ATPase and permease K06147 - - 1.473e-223 711.0
CMS2_k127_6981186_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K01847 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000008236 229.0
CMS2_k127_6981186_2 50S ribosomal protein L31 K02909 - - 0.00000000000000000000000000000000000008416 142.0
CMS2_k127_6995396_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 481.0
CMS2_k127_6995396_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000088 203.0
CMS2_k127_7016113_0 Trimethylamine methyltransferase (MTTB) - - - 3.247e-217 685.0
CMS2_k127_7016113_1 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000000000000000001569 226.0
CMS2_k127_7016113_2 Lysine exporter protein LysE YggA - - - 0.000000000000000000000000000000000000000000000001403 182.0
CMS2_k127_7016113_3 dioxygenase activity - - - 0.000001371 58.0
CMS2_k127_7029477_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 6.499e-260 812.0
CMS2_k127_7029477_1 deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 - 3.1.5.1 0.000000000000000000000000000000000000000006952 158.0
CMS2_k127_7042175_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 4.633e-219 685.0
CMS2_k127_7042175_1 acyl-CoA transferases carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 525.0
CMS2_k127_7042175_2 transport system, small permease component - - - 0.000000000000000000000000000000000000000000000000000000000007056 212.0
CMS2_k127_7042175_3 cation transport ATPase - - - 0.00000000000000000004149 92.0
CMS2_k127_7044209_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 2.265e-218 687.0
CMS2_k127_7044209_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 3.516e-208 659.0
CMS2_k127_7044209_2 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 476.0
CMS2_k127_7044209_3 COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000001895 237.0
CMS2_k127_7044209_4 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000001084 229.0
CMS2_k127_7047566_0 glutamine synthetase K01915 - 6.3.1.2 1.069e-273 849.0
CMS2_k127_7047566_1 PFAM Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 365.0
CMS2_k127_7047566_2 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000000000000563 93.0
CMS2_k127_7073610_0 Bacterial periplasmic substrate-binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000073 221.0
CMS2_k127_7073610_1 LysE type translocator - - - 0.00000000000000000000000000000000000000000000001165 173.0
CMS2_k127_7073610_2 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000001735 161.0
CMS2_k127_7073610_3 relative of glutathione S-transferase, MAPEG superfamily K07136 - - 0.000000000000000000002447 102.0
CMS2_k127_7079586_0 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 9.745e-230 722.0
CMS2_k127_7079586_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 3.024e-197 620.0
CMS2_k127_7079586_2 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 296.0
CMS2_k127_7079586_3 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003498 283.0
CMS2_k127_724737_0 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 370.0
CMS2_k127_724737_1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 368.0
CMS2_k127_724737_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 329.0
CMS2_k127_724737_3 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000004625 243.0
CMS2_k127_724737_4 Sulfotransferase domain - - - 0.000003583 49.0
CMS2_k127_742189_0 COG0625 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000535 280.0
CMS2_k127_742189_1 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000745 192.0
CMS2_k127_742189_2 - - - - 0.000000000008246 75.0
CMS2_k127_796944_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 493.0
CMS2_k127_796944_1 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 314.0
CMS2_k127_796944_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006451 290.0
CMS2_k127_807090_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 537.0
CMS2_k127_807090_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 440.0
CMS2_k127_807090_2 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000001284 224.0
CMS2_k127_807090_3 - - - - 0.00000000000000000000000000000000000000000000000009377 185.0
CMS2_k127_807090_4 Domain of unknown function (DUF1849) - - - 0.0000000000000000000000000000000000000003637 159.0
CMS2_k127_819095_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15785 - 2.6.1.76 3.866e-240 764.0
CMS2_k127_819095_1 Aldehyde dehydrogenase family K15786 - - 3.953e-202 642.0
CMS2_k127_819095_2 helix_turn_helix ASNC type K15782 - - 0.000000000000000000000000000000000000000000000000000000000000000006387 228.0
CMS2_k127_822338_0 COG0277 FAD FMN-containing dehydrogenases K00102 - 1.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 590.0
CMS2_k127_822338_1 COG1960 Acyl-CoA dehydrogenases K20035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 551.0
CMS2_k127_822338_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 357.0
CMS2_k127_822338_3 VirC1 protein K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 316.0
CMS2_k127_822338_4 YHS domain protein - - - 0.0000000000000000000000000000000000000000000000000005036 188.0
CMS2_k127_822338_5 Uncharacterized protein conserved in bacteria (DUF2312) - - - 0.0000000000000000000000000000001503 126.0
CMS2_k127_822338_6 Domain of unknown function (DUF4169) - - - 0.0004488 47.0
CMS2_k127_828621_0 SnoaL-like polyketide cyclase K07255 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000654 244.0
CMS2_k127_828621_1 protein conserved in bacteria K09987 - - 0.00000000000000000000000000000000000000000000000000000001104 201.0
CMS2_k127_828621_2 Lipocalin / cytosolic fatty-acid binding protein family K03098 - - 0.000000000000000000000000000000000000001137 155.0
CMS2_k127_828621_3 aminotransferase class V - - - 0.00000000000000000000000000000000002158 138.0
CMS2_k127_8306_0 Mg2 and Co2 transporter CorB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 548.0
CMS2_k127_8306_1 Cobaltochelatase CobS subunit N terminal K09882 - 6.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 470.0
CMS2_k127_8306_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 459.0
CMS2_k127_8306_3 Protein of unknown function (DUF2889) - - - 0.000000000000000000000000000000000000000000000000000000000000000001043 232.0
CMS2_k127_8306_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000001182 225.0
CMS2_k127_8306_5 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000001387 196.0
CMS2_k127_8306_6 Belongs to the BolA IbaG family K05527,K22066 - - 0.00000000000000000000000000000005581 130.0
CMS2_k127_8306_7 Ribbon-helix-helix domain - - - 0.0000000000000000000000001487 109.0
CMS2_k127_8306_8 - - - - 0.000007923 49.0
CMS2_k127_852275_0 COG2030 Acyl dehydratase K14449 - 4.2.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 492.0
CMS2_k127_852275_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 400.0
CMS2_k127_852275_2 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 348.0
CMS2_k127_852275_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 316.0
CMS2_k127_852275_4 Belongs to the pyridoxine kinase family K00868 - 2.7.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001319 288.0
CMS2_k127_880978_0 DNA helicase K03657 - 3.6.4.12 0.0 1041.0
CMS2_k127_880978_1 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 2.336e-292 908.0
CMS2_k127_880978_10 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000000000000000000000000001909 171.0
CMS2_k127_880978_11 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000102 151.0
CMS2_k127_880978_12 SnoaL-like polyketide cyclase - - - 0.0000000000000000000000000000000000001907 146.0
CMS2_k127_880978_13 COG2854 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.000000000000000000000000000000002155 137.0
CMS2_k127_880978_14 Staphylococcal nuclease homologue - - - 0.0000007594 58.0
CMS2_k127_880978_15 sh3 domain protein - - - 0.0000203 55.0
CMS2_k127_880978_2 Voltage gated chloride channel K03281 - - 4.209e-200 640.0
CMS2_k127_880978_3 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 582.0
CMS2_k127_880978_4 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 364.0
CMS2_k127_880978_5 ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 303.0
CMS2_k127_880978_6 Sodium Bile acid symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005877 284.0
CMS2_k127_880978_7 (Lipo)protein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000919 226.0
CMS2_k127_880978_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000006727 179.0
CMS2_k127_880978_9 Flavin containing amine oxidoreductase K06955 - - 0.00000000000000000000000000000000000000000000001386 181.0
CMS2_k127_895113_0 Heparinase II/III-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 514.0
CMS2_k127_895113_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 351.0
CMS2_k127_895113_2 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002345 266.0
CMS2_k127_895113_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000183 225.0
CMS2_k127_895113_4 Adenylate cyclase - - - 0.0000000000000000000000000000003843 134.0
CMS2_k127_895113_5 Protein of unknown function (DUF4242) - - - 0.00000000000000000000003443 114.0
CMS2_k127_895113_6 OsmC-like protein - - - 0.0000000000000000000001874 111.0
CMS2_k127_922093_0 Acetyl-coenzyme A transporter 1 K08218 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015835,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000001523 234.0
CMS2_k127_922093_1 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000006854 214.0
CMS2_k127_922093_2 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000001764 160.0
CMS2_k127_939901_0 PFAM SNF2-related protein K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 366.0
CMS2_k127_967101_0 malic enzyme K00029 - 1.1.1.40 0.0 1081.0
CMS2_k127_967101_1 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 568.0
CMS2_k127_967101_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 481.0
CMS2_k127_967101_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 329.0
CMS2_k127_967101_4 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 305.0
CMS2_k127_967101_5 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000004904 237.0
CMS2_k127_967101_6 protein, possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000000000001904 175.0
CMS2_k127_967101_7 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000000000000001738 166.0
CMS2_k127_967101_8 protein conserved in bacteria K09794 - - 0.00000000000000000000001106 102.0
CMS2_k127_969495_0 Transcriptional regulator K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 323.0
CMS2_k127_969495_1 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 297.0
CMS2_k127_969495_2 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000005233 190.0
CMS2_k127_969495_3 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 0.000000000000000000000000000000000000000003329 156.0
CMS2_k127_969495_4 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000005859 51.0
CMS2_k127_986317_0 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008211 355.0
CMS2_k127_986317_1 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 336.0
CMS2_k127_986317_2 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 336.0
CMS2_k127_986317_3 Glutathione S-transferase K07393 - 1.8.5.7 0.00000000000001995 81.0
CMS2_k127_995565_0 Biotin carboxylase - - - 6.658e-235 743.0
CMS2_k127_995565_1 COG1982 Arginine lysine ornithine decarboxylases K01584 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 411.0
CMS2_k127_995565_2 choloylglycine hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 387.0
CMS2_k127_995565_3 PFAM type III effector Hrp-dependent outers K21948 - 2.7.1.217 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 346.0
CMS2_k127_995565_4 Xylose isomerase-like TIM barrel K01816,K22131 - 5.3.1.22,5.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 325.0