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Overview

ID MAG00427
Name CMS2_bin.39
Sample SMP0011
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Nitrososphaeria
Order Nitrososphaerales
Family Nitrosopumilaceae
Genus Nitrosomaritimum
Species
Assembly information
Completeness (%) 78.83
Contamination (%) 0.22
GC content (%) 34.0
N50 (bp) 11,806
Genome size (bp) 1,090,213

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1300

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_114492_0 Domain of unknown function (DUF1297) K06863 - 6.3.4.23 1.099e-212 663.0
CMS2_k127_114492_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 487.0
CMS2_k127_114492_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 418.0
CMS2_k127_114492_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 338.0
CMS2_k127_114492_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000105 238.0
CMS2_k127_114492_5 - - - - 0.0000000000000000000000000000000000004745 140.0
CMS2_k127_114492_6 - - - - 0.0000000000000000000000000000000000005045 143.0
CMS2_k127_114492_7 HD domain K00951 - 2.7.6.5 0.0000000000000000000000000000006647 125.0
CMS2_k127_114492_8 mttA/Hcf106 family K03116 - - 0.00000000000000000000004012 100.0
CMS2_k127_1160953_0 resistance protein K14166 - - 0.0 1262.0
CMS2_k127_1160953_1 - - - - 9.549e-273 848.0
CMS2_k127_1160953_2 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 364.0
CMS2_k127_1160953_3 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008168 321.0
CMS2_k127_1160953_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003765 246.0
CMS2_k127_1160953_5 - - - - 0.000000000000000000000000000000000004316 137.0
CMS2_k127_1160953_6 - - - - 0.00000000000000000000000000000000002565 137.0
CMS2_k127_127253_0 Succinyl-CoA ligase like flavodoxin domain K18594 - - 0.0 1305.0
CMS2_k127_127253_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.178e-239 743.0
CMS2_k127_127253_10 Belongs to the enoyl-CoA hydratase isomerase family K15019 - 4.2.1.116 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000787 481.0
CMS2_k127_127253_11 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 467.0
CMS2_k127_127253_12 TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 447.0
CMS2_k127_127253_13 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 439.0
CMS2_k127_127253_14 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 422.0
CMS2_k127_127253_15 Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis) K05828 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 374.0
CMS2_k127_127253_16 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 346.0
CMS2_k127_127253_17 glutamine amidotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 308.0
CMS2_k127_127253_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 288.0
CMS2_k127_127253_19 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 293.0
CMS2_k127_127253_2 HMGL-like K01649 - 2.3.3.13 5.812e-236 733.0
CMS2_k127_127253_20 Cytidylyltransferase-like K00980,K14656 - 2.7.7.2,2.7.7.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006568 268.0
CMS2_k127_127253_21 Iron-sulfur cluster assembly accessory protein K13628 - - 0.0000000000000000000000000000000000000000000000000000000000000001067 222.0
CMS2_k127_127253_22 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000003209 166.0
CMS2_k127_127253_23 CBS domain - - - 0.0000000000000000000000000000000002459 135.0
CMS2_k127_127253_24 Multicopper - - - 0.000000000000000000000000000000001001 133.0
CMS2_k127_127253_25 lysine biosynthesis protein LysW K05826 - - 0.000000000000000000000000000003111 119.0
CMS2_k127_127253_26 lysine biosynthesis protein LysW K05826 - - 0.000000000000000000000000003162 111.0
CMS2_k127_127253_27 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000001259 102.0
CMS2_k127_127253_28 - - - - 0.00000000000000222 77.0
CMS2_k127_127253_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 - - 3.097e-233 724.0
CMS2_k127_127253_4 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily K05829 - - 1.415e-224 697.0
CMS2_k127_127253_5 DNA primase K02316 - - 4.567e-209 653.0
CMS2_k127_127253_6 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K05831 - - 5.947e-209 653.0
CMS2_k127_127253_7 diphthine synthase K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 593.0
CMS2_k127_127253_8 Lysine biosynthesis K05827 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 523.0
CMS2_k127_127253_9 Lysine biosynthesis K05827 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 497.0
CMS2_k127_1340597_0 synthetase (class II) K01880 - 6.1.1.14 1.209e-284 877.0
CMS2_k127_1340597_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 488.0
CMS2_k127_1340597_2 conserved protein implicated in secretion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 384.0
CMS2_k127_1340597_3 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000002735 189.0
CMS2_k127_1340597_4 Asp/Glu/Hydantoin racemase K01776 - 5.1.1.3 0.00000000000000000000000000000000000000003414 155.0
CMS2_k127_1426710_0 Multicopper - - - 0.0 1041.0
CMS2_k127_1426710_1 Major facilitator superfamily K08153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 569.0
CMS2_k127_1426710_2 homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 286.0
CMS2_k127_1430313_0 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002273 278.0
CMS2_k127_1430313_1 Glyoxalase-like domain K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000141 248.0
CMS2_k127_1430313_10 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000003204 81.0
CMS2_k127_1430313_12 - - - - 0.0000000000005482 72.0
CMS2_k127_1430313_13 Radical SAM K04069 - 1.97.1.4 0.000000000001046 68.0
CMS2_k127_1430313_2 CBS domain K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000998 249.0
CMS2_k127_1430313_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000000000000000000000000000008215 183.0
CMS2_k127_1430313_5 - - - - 0.000000000000000000000000000000000000000000000006229 175.0
CMS2_k127_1430313_6 - - - - 0.000000000000000000000000000000000000000000001064 168.0
CMS2_k127_1430313_7 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000001064 141.0
CMS2_k127_1430313_8 - - - - 0.00000000000000000000000000000006005 126.0
CMS2_k127_1430313_9 zinc finger - - - 0.0000000000000000001446 92.0
CMS2_k127_1534687_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 7.122e-261 808.0
CMS2_k127_1534687_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.245e-257 798.0
CMS2_k127_1534687_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 321.0
CMS2_k127_1534687_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000007458 143.0
CMS2_k127_1534687_4 - - - - 0.0000000000000000000000000004537 115.0
CMS2_k127_1535265_0 Hydroxymethylglutaryl-coenzyme A synthase N terminal K01641 - 2.3.3.10 4.744e-266 823.0
CMS2_k127_1535265_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 5.925e-231 720.0
CMS2_k127_1535265_2 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 340.0
CMS2_k127_1535265_3 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 340.0
CMS2_k127_1535265_4 - - - - 0.0000000000000000000000000000000000000000000000000000002444 198.0
CMS2_k127_1535265_5 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000001011 190.0
CMS2_k127_1535265_6 response regulator, receiver K03413 - - 0.0000000000005436 79.0
CMS2_k127_1545596_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 4.095e-264 818.0
CMS2_k127_1545596_1 Transporter associated domain - - - 3.058e-213 668.0
CMS2_k127_1545596_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 2.086e-198 621.0
CMS2_k127_1545596_3 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 296.0
CMS2_k127_1545596_4 - - - - 0.0000000000000000000000000000000000000000003817 159.0
CMS2_k127_1545596_5 xylanase chitin deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000001718 177.0
CMS2_k127_1545596_6 - - - - 0.0000000000000000000000000000586 120.0
CMS2_k127_1545596_7 - - - - 0.00000000000000000000000006578 124.0
CMS2_k127_1545596_8 - - - - 0.00000000000001747 72.0
CMS2_k127_1707044_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.0 1261.0
CMS2_k127_1707044_1 RNase L inhibitor, RLI K06174 - - 0.0 1079.0
CMS2_k127_1707044_10 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 415.0
CMS2_k127_1707044_11 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 355.0
CMS2_k127_1707044_12 4Fe-4S binding domain K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 339.0
CMS2_k127_1707044_13 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 320.0
CMS2_k127_1707044_14 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009238 300.0
CMS2_k127_1707044_15 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005831 289.0
CMS2_k127_1707044_16 NADH ubiquinone oxidoreductase subunit 11 or 4L (chain K) K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000000008036 172.0
CMS2_k127_1707044_17 - - - - 0.00000000000000000000000000000000000001051 147.0
CMS2_k127_1707044_18 HTH DNA binding domain - - - 0.0000000000000000000000000000007313 123.0
CMS2_k127_1707044_19 NADH dehydrogenase K00337 - 1.6.5.3 0.00000000000000002334 81.0
CMS2_k127_1707044_2 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0 1012.0
CMS2_k127_1707044_3 plastoquinone (complex I) K00342,K12137,K12141 - 1.6.5.3 4.007e-310 953.0
CMS2_k127_1707044_4 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K22169 - 1.5.98.3 9.778e-280 864.0
CMS2_k127_1707044_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 5.727e-242 755.0
CMS2_k127_1707044_6 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 583.0
CMS2_k127_1707044_7 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 575.0
CMS2_k127_1707044_8 Met-10+ like-protein K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 470.0
CMS2_k127_1707044_9 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 439.0
CMS2_k127_1774550_0 Sulfite reductase K00392 - 1.8.7.1 0.0 1023.0
CMS2_k127_1774550_1 Cysteine synthase K12339 - 2.5.1.47 1.463e-198 622.0
CMS2_k127_1774550_10 - - - - 0.000000000000000000000000000000000149 137.0
CMS2_k127_1774550_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 606.0
CMS2_k127_1774550_3 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 527.0
CMS2_k127_1774550_4 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 457.0
CMS2_k127_1774550_5 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 380.0
CMS2_k127_1774550_6 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 342.0
CMS2_k127_1774550_7 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 333.0
CMS2_k127_1774550_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 293.0
CMS2_k127_1774550_9 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000003435 149.0
CMS2_k127_1896241_0 von Willebrand factor (vWF) type A domain - - - 3.449e-278 861.0
CMS2_k127_1896241_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 344.0
CMS2_k127_1896241_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 283.0
CMS2_k127_1896241_3 ATPase family associated with various cellular activities (AAA) K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001661 263.0
CMS2_k127_1896241_4 ASCH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002354 231.0
CMS2_k127_1896241_5 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004514 243.0
CMS2_k127_1896241_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000003396 184.0
CMS2_k127_1896241_7 - - - - 0.0000000000000000000000000001519 116.0
CMS2_k127_1907123_0 COG1914 Mn2 and Fe2 transporters of the NRAMP family - - - 1.123e-202 637.0
CMS2_k127_1907123_1 Major Intrinsic Protein K06188,K09866 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 417.0
CMS2_k127_1907123_10 - - - - 0.0000000000000000001457 102.0
CMS2_k127_1907123_11 SnoaL-like domain - - - 0.00000000000004318 84.0
CMS2_k127_1907123_12 AhpC/TSA antioxidant enzyme K03564 - 1.11.1.15 0.0000000000006153 68.0
CMS2_k127_1907123_13 Protein of unknown function (DUF1059) - - - 0.00000003031 56.0
CMS2_k127_1907123_2 transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007481 366.0
CMS2_k127_1907123_3 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 319.0
CMS2_k127_1907123_4 PFAM Ferritin, Dps family protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 297.0
CMS2_k127_1907123_5 - - - - 0.00000000000000000000000000000000000000000000000000004417 190.0
CMS2_k127_1907123_7 - - - - 0.000000000000000000000000000000000002188 152.0
CMS2_k127_1907123_8 - - - - 0.0000000000000000000000000000001885 139.0
CMS2_k127_1907123_9 - - - - 0.0000000000000000000006218 110.0
CMS2_k127_1931913_0 DEAD DEAH box helicase K06877 - - 0.0 1439.0
CMS2_k127_1931913_1 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 5.224e-307 946.0
CMS2_k127_1931913_10 major facilitator superfamily K08153,K08221 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008086 379.0
CMS2_k127_1931913_11 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 377.0
CMS2_k127_1931913_12 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 346.0
CMS2_k127_1931913_13 Isocitrate isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 285.0
CMS2_k127_1931913_14 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000739 217.0
CMS2_k127_1931913_15 - - - - 0.00000000000000000000000000000000000000000000000000000002003 198.0
CMS2_k127_1931913_16 mttA/Hcf106 family K03116 - - 0.00000000000000000000000000000000000001201 147.0
CMS2_k127_1931913_17 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000002032 137.0
CMS2_k127_1931913_19 response regulator, receiver K03413,K07662,K07667 - - 0.00000000000000000000000000000125 124.0
CMS2_k127_1931913_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 543.0
CMS2_k127_1931913_20 - - - - 0.0000000000000000000000000001415 119.0
CMS2_k127_1931913_21 - - - - 0.0000000000000000000000000173 108.0
CMS2_k127_1931913_22 - - - - 0.00000000000000000000001222 100.0
CMS2_k127_1931913_23 CBS domain - - - 0.0000000000000000000002882 101.0
CMS2_k127_1931913_24 - - - - 0.000009161 49.0
CMS2_k127_1931913_3 Sodium hydrogen exchanger K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008428 500.0
CMS2_k127_1931913_4 DNA methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 477.0
CMS2_k127_1931913_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 454.0
CMS2_k127_1931913_6 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007752 450.0
CMS2_k127_1931913_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 452.0
CMS2_k127_1931913_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 441.0
CMS2_k127_1931913_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002427 427.0
CMS2_k127_198456_0 Radical SAM - - - 0.0 1136.0
CMS2_k127_198456_1 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 607.0
CMS2_k127_198456_10 Ribosomal protein S30 K02983 - - 0.00000000000000000000000000001303 117.0
CMS2_k127_198456_11 Pfam:Methyltransf_26 K02493 - 2.1.1.297 0.000000000000000000007134 99.0
CMS2_k127_198456_12 - - - - 0.000000000000008413 81.0
CMS2_k127_198456_2 Catalyzes the conversion of dihydroorotate to orotate K00226,K00254,K17723,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.1,1.3.1.14,1.3.5.2,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 533.0
CMS2_k127_198456_3 Isocitrate isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 422.0
CMS2_k127_198456_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 414.0
CMS2_k127_198456_5 RNA methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 368.0
CMS2_k127_198456_6 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 321.0
CMS2_k127_198456_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 306.0
CMS2_k127_198456_8 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000007253 190.0
CMS2_k127_198456_9 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.0000000000000000000000000000000000000000000000000005143 184.0
CMS2_k127_2015115_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 455.0
CMS2_k127_2015115_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 283.0
CMS2_k127_2015115_2 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 284.0
CMS2_k127_2015115_3 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003357 274.0
CMS2_k127_2015115_4 helix_turn_helix ASNC type K03718 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005815 254.0
CMS2_k127_2015115_5 UPF0126 domain - - - 0.0000000000000000000000000000000000000000000000000022 184.0
CMS2_k127_2015115_6 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000007536 140.0
CMS2_k127_2015115_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000000000000000000385 113.0
CMS2_k127_2027948_0 Radical SAM - - - 0.0 1047.0
CMS2_k127_2027948_1 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 552.0
CMS2_k127_2027948_2 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 529.0
CMS2_k127_2027948_3 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 410.0
CMS2_k127_2027948_4 tRNA methyl transferase K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 333.0
CMS2_k127_2027948_5 Cysteine desulfurase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000043 216.0
CMS2_k127_2027948_6 - - - - 0.0000000000000000000000000000000000000000000000003819 177.0
CMS2_k127_2027948_7 serine-type endopeptidase activity - - - 0.0000000000009922 68.0
CMS2_k127_2060214_0 UbiD family decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 574.0
CMS2_k127_2060214_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002088 270.0
CMS2_k127_2060214_2 - - - - 0.00000000000000000000000000000000000000000000000000000000003541 207.0
CMS2_k127_2060214_3 - - - - 0.00000000000000000000000000000000000000000000000000000000007936 206.0
CMS2_k127_2060214_4 - - - - 0.000000000000000000814 91.0
CMS2_k127_2060994_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01870 - 6.1.1.5 9.186e-300 925.0
CMS2_k127_2060994_1 ATP-grasp domain K01903 - 6.2.1.5 3.364e-205 642.0
CMS2_k127_2060994_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 366.0
CMS2_k127_2060994_3 Ferritin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 306.0
CMS2_k127_2060994_4 - - - - 0.0000000000000000000000000000000000000000000000003471 177.0
CMS2_k127_2060994_5 - - - - 0.0000000000000007307 77.0
CMS2_k127_2092632_0 Heme copper-type cytochrome quinol K02274 - 1.9.3.1 1.649e-254 786.0
CMS2_k127_2092632_1 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 376.0
CMS2_k127_2092632_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 355.0
CMS2_k127_2092632_3 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 344.0
CMS2_k127_2092632_4 Heme copper-type cytochrome quinol oxidases, subunit 2 K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005051 276.0
CMS2_k127_2092632_5 Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000000000000000000000000000008316 206.0
CMS2_k127_2092632_6 - - - - 0.000000000000000000000000000000000001543 140.0
CMS2_k127_2110478_0 PFAM aminotransferase class-III K01845 - 5.4.3.8 3.785e-232 722.0
CMS2_k127_2110478_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 386.0
CMS2_k127_2110478_2 Major Intrinsic Protein K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 341.0
CMS2_k127_2110478_3 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 293.0
CMS2_k127_2110478_4 regulatory protein, arsR K03892,K21903 - - 0.00000000000000000000000000000000000000000000000000662 181.0
CMS2_k127_2110478_5 Nitrogen regulatory protein P-II - - - 0.00000000000000000000000000000000000000000000001039 173.0
CMS2_k127_2110478_6 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000004536 172.0
CMS2_k127_2118927_0 - - - - 1.654e-207 653.0
CMS2_k127_2118927_1 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 595.0
CMS2_k127_2118927_2 geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 440.0
CMS2_k127_2118927_3 Protein of unknown function (DUF1698) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 325.0
CMS2_k127_2118927_4 Guanylyl transferase CofC like K14941 - 2.7.7.68 0.00000000000000000000000000000000000000000000000004759 181.0
CMS2_k127_2118927_6 - - - - 0.0000005439 53.0
CMS2_k127_2143302_0 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 460.0
CMS2_k127_2143302_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 382.0
CMS2_k127_2143302_2 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000000000000000000000000000000000000000000000003204 221.0
CMS2_k127_2143302_3 - - - - 0.00000000000000000000000000000000000000000000000000000000008887 208.0
CMS2_k127_2143302_4 Methyltransferase type 11 K03183 - 2.1.1.163,2.1.1.201 0.0000001161 53.0
CMS2_k127_2274465_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.973e-279 861.0
CMS2_k127_2274465_1 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 467.0
CMS2_k127_2274465_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 381.0
CMS2_k127_2274465_3 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003295 261.0
CMS2_k127_2274465_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000004698 237.0
CMS2_k127_2274465_5 Domain of unknown function (DUF427) - - - 0.0000000000000000000000000000000000000000000000000000009011 192.0
CMS2_k127_2274465_6 - - - - 0.0000000000000000000000000000000000000000000000001119 179.0
CMS2_k127_2274465_7 Pyridoxamine 5'-phosphate - - - 0.000000000000000000002172 94.0
CMS2_k127_2282696_0 Amino acid kinase family K00928 - 2.7.2.4 1.569e-229 718.0
CMS2_k127_2282696_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 575.0
CMS2_k127_2282696_2 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009844 474.0
CMS2_k127_2282696_3 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000008738 146.0
CMS2_k127_2282696_4 - - - - 0.00000000000000000000000000001042 120.0
CMS2_k127_2282696_5 - - - - 0.00000000000000000000000000002192 117.0
CMS2_k127_2282696_6 - - - - 0.000000000000000000000005309 102.0
CMS2_k127_2284682_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 550.0
CMS2_k127_2284682_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 371.0
CMS2_k127_2284682_10 - - - - 0.000000000000000000000000001926 117.0
CMS2_k127_2284682_11 Histidine kinase - - - 0.00000000000000000000000003959 126.0
CMS2_k127_2284682_12 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000006961 97.0
CMS2_k127_2284682_13 response regulator, receiver K02485,K02490,K03413 - - 0.0000000000000000003989 92.0
CMS2_k127_2284682_14 - - - - 0.0000000000533 70.0
CMS2_k127_2284682_15 Metallo-beta-lactamase superfamily - - - 0.000004427 54.0
CMS2_k127_2284682_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 369.0
CMS2_k127_2284682_3 PBS lyase HEAT-like repeat K06072 - 1.14.99.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 289.0
CMS2_k127_2284682_4 copper ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 288.0
CMS2_k127_2284682_5 Ribosomal protein L15E K02877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008185 271.0
CMS2_k127_2284682_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001316 265.0
CMS2_k127_2284682_7 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000003052 209.0
CMS2_k127_2284682_8 - - - - 0.000000000000000000000000000000000000000000000000000000001925 206.0
CMS2_k127_2284682_9 gluconolactonase activity K01179,K07004,K14274 - 3.2.1.4 0.000000000000000000000000000000000003964 155.0
CMS2_k127_2309256_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000373 239.0
CMS2_k127_2309256_1 COG0607 Rhodanese-related sulfurtransferase K03406,K21028 - 2.8.1.11 0.000000000000000000000000003196 118.0
CMS2_k127_2309256_2 response regulator, receiver K03413,K07662,K07667 - - 0.00000000000000000000000002692 111.0
CMS2_k127_2309256_3 - - - - 0.0000000006316 66.0
CMS2_k127_2323310_0 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 604.0
CMS2_k127_2323310_1 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006481 256.0
CMS2_k127_2323310_2 PFAM Integral membrane protein TerC K05794 - - 0.0000000000001731 74.0
CMS2_k127_2352439_0 Radical SAM K18285 - 2.5.1.120 2.981e-202 633.0
CMS2_k127_2352439_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004918 308.0
CMS2_k127_2352439_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K07646,K20989 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000001521 211.0
CMS2_k127_2352439_3 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000005163 205.0
CMS2_k127_2352439_4 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000215 196.0
CMS2_k127_2352439_5 Thiamine-binding protein - - - 0.00000000000000000000000000000000104 132.0
CMS2_k127_2418753_0 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 4.028e-224 699.0
CMS2_k127_2418753_1 Tubulin/FtsZ family, GTPase domain K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 472.0
CMS2_k127_2418753_2 Belongs to the ribosomal protein L31e family K02910 - - 0.0000000000000000000000000000000000000000001378 161.0
CMS2_k127_2418753_3 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.000000000004075 65.0
CMS2_k127_2423320_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 0.0 1304.0
CMS2_k127_2423320_1 antibiotic catabolic process K18235 - - 9.692e-224 704.0
CMS2_k127_2423320_10 Domain of unknown function (DUF2024) - - - 0.0000000000000000000000000000000000000000000000003749 175.0
CMS2_k127_2423320_11 metal-dependent protease of the PAD1 JAB1 superfamily K21140 - 3.13.1.6 0.0000000000000000000000000000000000000000009221 162.0
CMS2_k127_2423320_12 - - - - 0.000000000000000000000000000000000000001919 148.0
CMS2_k127_2423320_13 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000000000000000000000000000001722 139.0
CMS2_k127_2423320_14 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.000000000000000000000000000000000004003 136.0
CMS2_k127_2423320_15 - - - - 0.00000000000000000000000000512 110.0
CMS2_k127_2423320_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.611e-204 638.0
CMS2_k127_2423320_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 596.0
CMS2_k127_2423320_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 494.0
CMS2_k127_2423320_5 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 467.0
CMS2_k127_2423320_6 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004014 272.0
CMS2_k127_2423320_7 tRNA pseudouridine synthase K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000018 251.0
CMS2_k127_2423320_8 Peptidyl-tRNA hydrolase PTH2 K04794 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000001195 232.0
CMS2_k127_2423320_9 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000000000000002219 179.0
CMS2_k127_2428180_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.265e-217 678.0
CMS2_k127_2428180_1 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 565.0
CMS2_k127_2428180_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 335.0
CMS2_k127_2428180_3 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 314.0
CMS2_k127_2428180_4 Alba K03622 - - 0.000000000000000000000000000000000000000000000000002547 184.0
CMS2_k127_2428180_5 - - - - 0.00000000000003459 74.0
CMS2_k127_2473018_0 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 472.0
CMS2_k127_2473018_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 375.0
CMS2_k127_2473018_2 Cobalamin B12-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 371.0
CMS2_k127_2473018_3 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 312.0
CMS2_k127_2473018_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003569 247.0
CMS2_k127_2501166_0 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 2.009e-268 828.0
CMS2_k127_2501166_1 phosphoglycerate mutase K15635 - 5.4.2.12 5.652e-231 720.0
CMS2_k127_2501166_10 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 441.0
CMS2_k127_2501166_11 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 439.0
CMS2_k127_2501166_12 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 365.0
CMS2_k127_2501166_13 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 339.0
CMS2_k127_2501166_14 Acetyltransferase (GNAT) domain K00621 - 2.3.1.4 0.00000000000000000000000000000000000000000000000000000000311 202.0
CMS2_k127_2501166_15 - - - - 0.00000000000000000000000000000000000000003873 156.0
CMS2_k127_2501166_16 Shikimate kinase K00891 - 2.7.1.71 0.0000000000000000000000000000000000002096 152.0
CMS2_k127_2501166_17 Mut7-C RNAse domain K09122 - - 0.000000000000001616 78.0
CMS2_k127_2501166_18 Domain of unknown function (DUF309) - - - 0.000000000005048 73.0
CMS2_k127_2501166_19 NUDIX domain K08310 - 3.6.1.67 0.00000007387 59.0
CMS2_k127_2501166_2 Chorismate mutase type II K00812 - 2.6.1.1 3.126e-230 719.0
CMS2_k127_2501166_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 2.021e-204 639.0
CMS2_k127_2501166_4 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 7.366e-204 637.0
CMS2_k127_2501166_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 9.517e-200 629.0
CMS2_k127_2501166_6 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 603.0
CMS2_k127_2501166_7 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 531.0
CMS2_k127_2501166_8 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 510.0
CMS2_k127_2501166_9 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 479.0
CMS2_k127_2555277_0 small GTP-binding protein K06944 - - 3.319e-216 673.0
CMS2_k127_2555277_1 Phosphoglycolate phosphatase K22223 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 362.0
CMS2_k127_2555277_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000001024 250.0
CMS2_k127_2579901_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 2.138e-298 921.0
CMS2_k127_2579901_1 Histone acetyltransferase K07739 - 2.3.1.48 4.546e-288 890.0
CMS2_k127_2579901_2 Sodium hydrogen exchanger - - - 8.358e-210 657.0
CMS2_k127_2579901_3 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000006399 198.0
CMS2_k127_2579901_4 - - - - 0.000000000000000000000000000000000000000000000001113 184.0
CMS2_k127_2579901_5 - - - - 0.0000000000000000000000000008756 113.0
CMS2_k127_2579901_6 - - - - 0.00000000000000003081 82.0
CMS2_k127_2591084_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 2151.0
CMS2_k127_2591084_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1394.0
CMS2_k127_2591084_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 321.0
CMS2_k127_2591084_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 318.0
CMS2_k127_2591084_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.000000000000000000000000000000000000000000000128 168.0
CMS2_k127_2591084_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000004438 137.0
CMS2_k127_26893_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 3.634e-243 754.0
CMS2_k127_26893_1 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 399.0
CMS2_k127_26893_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002308 241.0
CMS2_k127_26893_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000005912 124.0
CMS2_k127_2793312_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1294.0
CMS2_k127_2793312_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 6.436e-274 846.0
CMS2_k127_2793312_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002161 261.0
CMS2_k127_2793312_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000004449 232.0
CMS2_k127_2793312_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001355 232.0
CMS2_k127_2793312_13 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000001285 213.0
CMS2_k127_2793312_14 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000000000000000000003155 201.0
CMS2_k127_2793312_15 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000000000000004537 173.0
CMS2_k127_2793312_16 CBS domain - - - 0.0000000000000000000000000000000000000000000002301 170.0
CMS2_k127_2793312_17 - - - - 0.00000000000000000000000000000000002 135.0
CMS2_k127_2793312_18 carbon-nitrogen ligase activity, with glutamine as amido-N-donor - - - 0.00000000000000000000000000118 116.0
CMS2_k127_2793312_19 small metal-binding protein - - - 0.00000000000000000000009411 98.0
CMS2_k127_2793312_2 COG1252 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 6.126e-225 704.0
CMS2_k127_2793312_20 AbrB family - - - 0.0000000000000000974 79.0
CMS2_k127_2793312_3 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 1.171e-203 645.0
CMS2_k127_2793312_4 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006839 499.0
CMS2_k127_2793312_5 TIGRFAM precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 414.0
CMS2_k127_2793312_6 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 394.0
CMS2_k127_2793312_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 353.0
CMS2_k127_2793312_8 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 304.0
CMS2_k127_2793312_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001017 263.0
CMS2_k127_2868439_0 nucleotidyltransferase activity K07076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 444.0
CMS2_k127_2868439_1 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004658 272.0
CMS2_k127_2868439_2 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000000000000000000000002103 214.0
CMS2_k127_2982776_0 DEAD DEAH box helicase domain protein K03703,K10896 - - 3.158e-250 778.0
CMS2_k127_2982776_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 511.0
CMS2_k127_2982776_2 Restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 290.0
CMS2_k127_2982776_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000007632 210.0
CMS2_k127_2982776_4 PPIC-type PPIASE domain K07533 - 5.2.1.8 0.000000000000000000000000000000000000000000002162 166.0
CMS2_k127_2982776_5 - - - - 0.0000000000000009243 79.0
CMS2_k127_3039244_0 RNA-metabolising metallo-beta-lactamase K07041 - - 0.0 1225.0
CMS2_k127_3039244_1 ABC1 family - - - 1.7e-247 772.0
CMS2_k127_3039244_10 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 584.0
CMS2_k127_3039244_11 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 575.0
CMS2_k127_3039244_12 ATP synthase (C/AC39) subunit K02119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 539.0
CMS2_k127_3039244_13 Phosphate uptake regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 529.0
CMS2_k127_3039244_14 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 523.0
CMS2_k127_3039244_15 Tetrapyrrole (Corrin/Porphyrin) Methylases K05934 - 2.1.1.131 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 488.0
CMS2_k127_3039244_16 AsnC-type helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 434.0
CMS2_k127_3039244_17 Cob(II)yrinic acid a,c-diamide reductase K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008547 425.0
CMS2_k127_3039244_18 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 417.0
CMS2_k127_3039244_19 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 419.0
CMS2_k127_3039244_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 7.331e-226 704.0
CMS2_k127_3039244_20 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 409.0
CMS2_k127_3039244_21 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 404.0
CMS2_k127_3039244_22 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 406.0
CMS2_k127_3039244_23 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 402.0
CMS2_k127_3039244_24 Pfam:DUF137 K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 367.0
CMS2_k127_3039244_25 ABC-type antimicrobial peptide transport system, ATPase component K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 347.0
CMS2_k127_3039244_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 330.0
CMS2_k127_3039244_27 CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 326.0
CMS2_k127_3039244_28 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 315.0
CMS2_k127_3039244_29 thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 307.0
CMS2_k127_3039244_3 FtsX-like permease family K09808 - - 4.325e-223 695.0
CMS2_k127_3039244_30 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 299.0
CMS2_k127_3039244_31 peptidyl-prolyl cis-trans isomerase K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 286.0
CMS2_k127_3039244_32 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002166 251.0
CMS2_k127_3039244_33 Cytidylyltransferase-like K00952 - 2.7.7.1 0.000000000000000000000000000000000000000000000000000000000000000000004132 237.0
CMS2_k127_3039244_34 - - - - 0.000000000000000000000000000000000000000000000000000000000002771 212.0
CMS2_k127_3039244_35 dUTPase - - - 0.000000000000000000000000000000000000000000000000000000000005425 209.0
CMS2_k127_3039244_36 Tetrahydromethanopterin S-methyltransferase, subunit A K00577 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000002284 203.0
CMS2_k127_3039244_37 - - - - 0.000000000000000000000000000000000000000000000000000000003421 203.0
CMS2_k127_3039244_38 - - - - 0.0000000000000000000000000000000000000000000000000000002232 196.0
CMS2_k127_3039244_39 - - - - 0.000000000000000000000000000000000000000000000000000006622 194.0
CMS2_k127_3039244_4 - - - - 1.921e-210 663.0
CMS2_k127_3039244_40 - - - - 0.0000000000000000000000000000000000000000000000001226 181.0
CMS2_k127_3039244_41 - - - - 0.000000000000000000000000000000000000000000000001049 176.0
CMS2_k127_3039244_42 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000000000000000001331 168.0
CMS2_k127_3039244_43 - - - - 0.000000000000000000000000000000000000000000324 164.0
CMS2_k127_3039244_44 - - - - 0.00000000000000000000000000000000000000002131 157.0
CMS2_k127_3039244_45 - - - - 0.0000000000000000000000000000000000000777 143.0
CMS2_k127_3039244_46 - - - - 0.0000000000000000000000000000000004018 131.0
CMS2_k127_3039244_47 IMP dehydrogenase activity - - - 0.0000000000000000000000000002685 113.0
CMS2_k127_3039244_48 - - - - 0.000000000000000000000000001285 112.0
CMS2_k127_3039244_49 zinc finger - - - 0.000000000000000000000000003271 111.0
CMS2_k127_3039244_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 5.778e-204 641.0
CMS2_k127_3039244_50 - - - - 0.0000000000000000001024 92.0
CMS2_k127_3039244_53 - - - - 0.000006086 52.0
CMS2_k127_3039244_54 Domain of unknown function (DUF4149) - - - 0.0001163 51.0
CMS2_k127_3039244_6 extracellular matrix structural constituent - - - 7.425e-203 639.0
CMS2_k127_3039244_7 Aminotransferase class-V - - - 4.292e-196 616.0
CMS2_k127_3039244_8 Tyrosine--tRNA ligase K01866 - 6.1.1.1 1.865e-194 610.0
CMS2_k127_3039244_9 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 3.313e-194 609.0
CMS2_k127_3056142_0 Anticodon-binding domain of tRNA K01873 - 6.1.1.9 0.0 1111.0
CMS2_k127_3056142_1 aconitate hydratase K01681 - 4.2.1.3 0.0 1007.0
CMS2_k127_3056142_2 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 567.0
CMS2_k127_3056142_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 282.0
CMS2_k127_3056142_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001627 248.0
CMS2_k127_3108908_0 TIGRFAM glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 - 2.6.1.16 5.225e-293 907.0
CMS2_k127_3108908_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 3.518e-219 684.0
CMS2_k127_3108908_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000003079 51.0
CMS2_k127_3108908_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 379.0
CMS2_k127_3108908_3 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX K17759 - 5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 370.0
CMS2_k127_3108908_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 344.0
CMS2_k127_3108908_5 Translin family K07477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 298.0
CMS2_k127_3108908_6 Belongs to the UPF0284 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006014 304.0
CMS2_k127_3108908_7 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000001484 183.0
CMS2_k127_3108908_8 - - - - 0.00000000000000000000000000000000000000000000000003301 190.0
CMS2_k127_3108908_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.000000000000000000000000000000000000000000000003266 173.0
CMS2_k127_3173320_0 Sodium:sulfate symporter transmembrane region K14445 - - 1.724e-243 758.0
CMS2_k127_3173320_1 PFAM Alcohol dehydrogenase GroES-like domain - - - 6.338e-232 718.0
CMS2_k127_3173320_10 - - - - 0.000000000000000000000000000000000000000000000000001557 186.0
CMS2_k127_3173320_11 - - - - 0.000000000000000000000000000000000000000000000000001589 187.0
CMS2_k127_3173320_12 - - - - 0.000000000000000000000000000000000000000000000000006874 183.0
CMS2_k127_3173320_13 - - - - 0.00000000000000000000000000000000000000001054 156.0
CMS2_k127_3173320_14 Universal stress protein family - - - 0.00000000000000000000000000000000000000116 152.0
CMS2_k127_3173320_15 - - - - 0.00000000000000000000000000000000000000181 150.0
CMS2_k127_3173320_16 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K07646,K20989 - 2.7.13.3 0.0000000000000000000000000000000000007328 144.0
CMS2_k127_3173320_17 Universal stress protein - - - 0.000000000000000000000000000000003131 133.0
CMS2_k127_3173320_18 - - - - 0.00000000000000000000000000000008318 126.0
CMS2_k127_3173320_19 Universal stress protein family - - - 0.000000000000000000000000000003072 125.0
CMS2_k127_3173320_2 NAD-dependent epimerase dehydratase K01710 - 4.2.1.46 3.76e-221 692.0
CMS2_k127_3173320_21 - - - - 0.00000000000000000001308 96.0
CMS2_k127_3173320_23 - - - - 0.000000000000000216 86.0
CMS2_k127_3173320_24 - - - - 0.0000000000000007711 79.0
CMS2_k127_3173320_25 protoporphyrinogen oxidase activity K00231 - 1.3.3.15,1.3.3.4 0.000000000000004763 88.0
CMS2_k127_3173320_27 Lysylphosphatidylglycerol synthase TM region - - - 0.0000000001926 72.0
CMS2_k127_3173320_28 - - - - 0.000004329 51.0
CMS2_k127_3173320_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 571.0
CMS2_k127_3173320_4 Cobalamin B12-binding domain protein K16955,K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 387.0
CMS2_k127_3173320_5 Sensory domain in DIguanylate Cyclases and Two-component system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 322.0
CMS2_k127_3173320_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 292.0
CMS2_k127_3173320_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002152 265.0
CMS2_k127_3173320_8 PFAM DNA photolyase FAD-binding K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002756 262.0
CMS2_k127_3173320_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009754 237.0
CMS2_k127_3237446_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 598.0
CMS2_k127_3237446_1 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 462.0
CMS2_k127_3237446_10 THUMP domain K06963 - - 0.00000000000000000000000000000000000000000000001125 177.0
CMS2_k127_3237446_11 - - - - 0.000000000000000000000000000000000000000008782 161.0
CMS2_k127_3237446_12 - - - - 0.000000000000000000000000000000004603 132.0
CMS2_k127_3237446_13 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000001752 131.0
CMS2_k127_3237446_14 - - - - 0.00000000000000000000000000000002469 126.0
CMS2_k127_3237446_15 ribosomal protein K02962 - - 0.000000000000000000127 93.0
CMS2_k127_3237446_2 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 422.0
CMS2_k127_3237446_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 370.0
CMS2_k127_3237446_4 Kinase binding protein CGI-121 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 329.0
CMS2_k127_3237446_5 Sua5 YciO YrdC YwlC family K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004383 268.0
CMS2_k127_3237446_6 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000002225 228.0
CMS2_k127_3237446_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000005022 217.0
CMS2_k127_3237446_8 Bacterial Fe(2+) trafficking - - - 0.000000000000000000000000000000000000000000000004173 173.0
CMS2_k127_3237446_9 Winged helix-turn-helix - - - 0.000000000000000000000000000000000000000000000004173 173.0
CMS2_k127_3259796_0 - - - - 1.178e-195 618.0
CMS2_k127_3259796_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 373.0
CMS2_k127_3259796_10 - - - - 0.000003566 55.0
CMS2_k127_3259796_2 NAD(P)H-dependent FMN reductase K00299 - 1.5.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000006 244.0
CMS2_k127_3259796_3 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000000000000000000000000001015 199.0
CMS2_k127_3259796_4 - - - - 0.0000000000000000000000000000000000000004069 149.0
CMS2_k127_3259796_5 - - - - 0.0000000000000000000004504 96.0
CMS2_k127_3259796_6 - - - - 0.0000000000000000000004725 95.0
CMS2_k127_3259796_7 Belongs to the universal stress protein A family - - - 0.0000000000002336 75.0
CMS2_k127_3259796_9 small metal-binding protein - - - 0.00000000001261 65.0
CMS2_k127_3262648_0 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 350.0
CMS2_k127_3262648_1 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000000000000000000000000000001919 170.0
CMS2_k127_3262648_2 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) - - - 0.00000000000000000000000000000000000000000008929 167.0
CMS2_k127_3262648_3 transcription factor (CBF NF-Y) - - - 0.000000000000000000000000000003005 120.0
CMS2_k127_3284628_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.0 1067.0
CMS2_k127_3284628_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 1.506e-285 883.0
CMS2_k127_3284628_10 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000002087 233.0
CMS2_k127_3284628_11 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000000000000000000000000000000000006356 176.0
CMS2_k127_3284628_12 - - - - 0.00000000000000000000000000000000006194 141.0
CMS2_k127_3284628_13 - - - - 0.0000000000000000000005179 100.0
CMS2_k127_3284628_14 - - - - 0.00000000000000000002488 91.0
CMS2_k127_3284628_15 - - - - 0.00000000000000001782 84.0
CMS2_k127_3284628_16 - - - - 0.000000000003384 70.0
CMS2_k127_3284628_17 - - - - 0.0000002162 63.0
CMS2_k127_3284628_18 - - - - 0.000001881 60.0
CMS2_k127_3284628_19 - - - - 0.00009106 46.0
CMS2_k127_3284628_2 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 4.294e-199 644.0
CMS2_k127_3284628_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 593.0
CMS2_k127_3284628_4 transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 329.0
CMS2_k127_3284628_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 302.0
CMS2_k127_3284628_6 PUA domain K07575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001751 260.0
CMS2_k127_3284628_7 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006133 261.0
CMS2_k127_3284628_8 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000811 266.0
CMS2_k127_3284628_9 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008598 244.0
CMS2_k127_3317060_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 7.596e-255 789.0
CMS2_k127_3317060_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 477.0
CMS2_k127_3317060_10 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000000000000000000000000000000000000001337 176.0
CMS2_k127_3317060_11 DoxX family K15977,K16937 - 1.8.5.2 0.0000000000000000000000000000000000000000000005419 169.0
CMS2_k127_3317060_12 Universal stress protein - - - 0.0000000000000000000000000000000000007883 143.0
CMS2_k127_3317060_13 protein secretion by the type IV secretion system - - - 0.00000000000000000000000000000000004757 147.0
CMS2_k127_3317060_14 - - - - 0.0000000000000000000000000000000001801 135.0
CMS2_k127_3317060_15 Universal stress protein - - - 0.000000000000000000000000000002294 125.0
CMS2_k127_3317060_16 - - - - 0.00000000000000000000000000001171 119.0
CMS2_k127_3317060_17 - - - - 0.00000000000000000000000000001433 121.0
CMS2_k127_3317060_18 CBS domain - - - 0.0000000000000000000000001457 111.0
CMS2_k127_3317060_19 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000000000007202 98.0
CMS2_k127_3317060_2 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 440.0
CMS2_k127_3317060_20 - - - - 0.000000000000000000001093 98.0
CMS2_k127_3317060_21 Uncharacterized conserved protein (DUF2196) - - - 0.0000000000000000007456 90.0
CMS2_k127_3317060_22 - - - - 0.00000000000003877 74.0
CMS2_k127_3317060_23 - - - - 0.00000000000141 72.0
CMS2_k127_3317060_26 Domain of unknown function (DUF309) K09763 - - 0.00000839 48.0
CMS2_k127_3317060_3 Chlorophyllase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 407.0
CMS2_k127_3317060_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 396.0
CMS2_k127_3317060_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 304.0
CMS2_k127_3317060_6 Functions by promoting the formation of the first peptide bond K03263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001591 258.0
CMS2_k127_3317060_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006565 254.0
CMS2_k127_3317060_8 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000000001186 220.0
CMS2_k127_3317060_9 Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.0000000000000000000000000000000000000000000000000004816 188.0
CMS2_k127_336873_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0 1096.0
CMS2_k127_336873_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 552.0
CMS2_k127_336873_2 oxidoreductase FAD NAD(P)-binding K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009337 535.0
CMS2_k127_336873_3 glycosyl transferase family K01001 - 2.7.8.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 472.0
CMS2_k127_336873_4 Nicotinamide-nucleotide adenylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 306.0
CMS2_k127_336873_5 Oxidoreductase family, NAD-binding Rossmann fold K18855 - 1.1.1.374 0.000000000000000000000000000000000000000000000000000000001055 211.0
CMS2_k127_336873_6 HEAT repeats - - - 0.00000000000000000000000000000000000000000000000000000000244 205.0
CMS2_k127_336873_7 Trm112p-like protein - - - 0.0000000000000000000000000000000000008465 140.0
CMS2_k127_336873_8 - - - - 0.000000000000000003782 87.0
CMS2_k127_336873_9 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000001861 58.0
CMS2_k127_3415840_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0 1140.0
CMS2_k127_3415840_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0 1101.0
CMS2_k127_3415840_10 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 289.0
CMS2_k127_3415840_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002155 255.0
CMS2_k127_3415840_12 Ribbon-helix-helix protein, copG family K07722 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001829 239.0
CMS2_k127_3415840_13 Periplasmic solute binding protein K09815 - - 0.000000000000000000000000000000000000000000000000000000000000000000003371 245.0
CMS2_k127_3415840_14 ATP synthase subunit C K02124 - - 0.000000000000000000000000000000004007 130.0
CMS2_k127_3415840_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 4.426e-285 878.0
CMS2_k127_3415840_3 copper ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 612.0
CMS2_k127_3415840_4 aspartate carbamoyltransferase K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 528.0
CMS2_k127_3415840_5 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 442.0
CMS2_k127_3415840_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 418.0
CMS2_k127_3415840_7 PFAM ABC transporter K09817 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 413.0
CMS2_k127_3415840_8 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 374.0
CMS2_k127_3415840_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 370.0
CMS2_k127_3468672_0 TCP-1/cpn60 chaperonin family K22447 - - 1.618e-308 949.0
CMS2_k127_3468672_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 1.127e-297 921.0
CMS2_k127_3468672_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001734 238.0
CMS2_k127_3468672_11 Lrp/AsnC ligand binding domain K03718 - - 0.00000000000000000000000000000000000000000000000000000000000000000294 228.0
CMS2_k127_3468672_12 - - - - 0.0000000000000000000000000000000000000000000000000000002392 195.0
CMS2_k127_3468672_13 Binds to the 23S rRNA K02929 - - 0.00000000000000000000000000000000000000000000000001587 180.0
CMS2_k127_3468672_14 Domain of unknown function (DUF2024) - - - 0.0000000000000000000000000000000000000000007825 157.0
CMS2_k127_3468672_15 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000001098 109.0
CMS2_k127_3468672_16 - - - - 0.00000000000000000000008356 98.0
CMS2_k127_3468672_17 PFAM ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000001555 66.0
CMS2_k127_3468672_18 - - - - 0.000002725 49.0
CMS2_k127_3468672_19 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000259 53.0
CMS2_k127_3468672_2 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 1.977e-214 668.0
CMS2_k127_3468672_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 554.0
CMS2_k127_3468672_4 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 531.0
CMS2_k127_3468672_5 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 452.0
CMS2_k127_3468672_6 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 444.0
CMS2_k127_3468672_7 ROK family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 438.0
CMS2_k127_3468672_8 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 400.0
CMS2_k127_3468672_9 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.000000000000000000000000000000000000000000000000000000000000000000001296 242.0
CMS2_k127_3504136_0 phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 1.026e-269 838.0
CMS2_k127_3504136_1 aconitate hydratase K01681 - 4.2.1.3 3.036e-235 730.0
CMS2_k127_3504136_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 398.0
CMS2_k127_3504136_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 324.0
CMS2_k127_3504136_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 327.0
CMS2_k127_3504136_5 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000129 243.0
CMS2_k127_3504136_6 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000000000000004047 158.0
CMS2_k127_3504136_7 - - - - 0.000000000000000000000002957 103.0
CMS2_k127_3542662_0 DEAD DEAH box helicase K05592 - 3.6.4.13 5.609e-240 746.0
CMS2_k127_3542662_1 Belongs to the Pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004174 385.0
CMS2_k127_3542662_2 - - - - 0.0000000000000000000000000000000000000000000000000000007215 193.0
CMS2_k127_3542662_3 - - - - 0.0000000000000000000000000000000000000000000000000002472 190.0
CMS2_k127_3542662_4 - - - - 0.0000000000000000000000000000000000007694 140.0
CMS2_k127_3542662_5 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000001599 133.0
CMS2_k127_3578332_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 498.0
CMS2_k127_3578332_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 500.0
CMS2_k127_3578332_2 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 452.0
CMS2_k127_3578332_3 Pterin binding enzyme K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 411.0
CMS2_k127_3578332_4 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 336.0
CMS2_k127_3578332_5 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000465 235.0
CMS2_k127_3578332_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002043 228.0
CMS2_k127_3578332_7 - - - - 0.000000000000000000000000000000000000000000000002968 177.0
CMS2_k127_3580170_0 Sodium hydrogen exchanger K11105 - - 5.571e-220 689.0
CMS2_k127_3580170_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 510.0
CMS2_k127_3580170_10 GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 326.0
CMS2_k127_3580170_11 CBS domain K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 322.0
CMS2_k127_3580170_12 conserved protein implicated in secretion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 298.0
CMS2_k127_3580170_13 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 290.0
CMS2_k127_3580170_14 COG1938 Archaeal enzymes of ATP-grasp superfamily K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001107 282.0
CMS2_k127_3580170_15 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000008994 208.0
CMS2_k127_3580170_16 - - - - 0.0000000000000000000000000000000000000000000000000000000002068 205.0
CMS2_k127_3580170_17 - - - - 0.0000000000000000000000000000000000000000000000000000002255 198.0
CMS2_k127_3580170_18 Winged helix-turn-helix - - - 0.00000000000000000000000000000000000000000000009394 169.0
CMS2_k127_3580170_19 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.0000000000000000000000000000000000000000000001753 171.0
CMS2_k127_3580170_2 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 470.0
CMS2_k127_3580170_20 - - - - 0.000000000000000000000000000000000000000000006771 164.0
CMS2_k127_3580170_21 - - - - 0.000000000000000000000000000000000000000001259 160.0
CMS2_k127_3580170_22 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000004776 153.0
CMS2_k127_3580170_23 - - - - 0.00000000000000000000000000000000000003251 144.0
CMS2_k127_3580170_24 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000001118 147.0
CMS2_k127_3580170_25 - - - - 0.000000000000000000000000000000000005925 136.0
CMS2_k127_3580170_26 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000000005449 135.0
CMS2_k127_3580170_27 - - - - 0.00000000000000000000000000000000306 130.0
CMS2_k127_3580170_28 - - - - 0.000000000000000000000000000000379 123.0
CMS2_k127_3580170_29 - - - - 0.00000000000000000000000000001042 119.0
CMS2_k127_3580170_3 Inositol monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000854 453.0
CMS2_k127_3580170_30 - - - - 0.000000000000000000000000003867 111.0
CMS2_k127_3580170_31 - - - - 0.0000000000000000000000002435 118.0
CMS2_k127_3580170_32 - - - - 0.0000000000000000000001744 99.0
CMS2_k127_3580170_33 AMP binding - - - 0.000000000000001068 83.0
CMS2_k127_3580170_34 CBS domain - - - 0.00000000355 68.0
CMS2_k127_3580170_35 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000007642 61.0
CMS2_k127_3580170_4 Conserved hypothetical ATP binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 421.0
CMS2_k127_3580170_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 405.0
CMS2_k127_3580170_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 398.0
CMS2_k127_3580170_7 membrane-associated protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 392.0
CMS2_k127_3580170_8 Queuosine biosynthesis protein QueC K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 386.0
CMS2_k127_3580170_9 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 387.0
CMS2_k127_360962_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 8.428e-208 649.0
CMS2_k127_360962_1 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 584.0
CMS2_k127_36361_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.931e-204 639.0
CMS2_k127_36361_1 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 381.0
CMS2_k127_36361_2 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 327.0
CMS2_k127_36361_3 - - - - 0.0000000000000000000000000000000000000000000000000000001333 196.0
CMS2_k127_36361_4 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000001993 145.0
CMS2_k127_36361_5 - - - - 0.00000000000000000000000000000000007324 134.0
CMS2_k127_3647166_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 2.249e-221 689.0
CMS2_k127_3647166_1 Protein of unknown function (DUF521) K09123 - - 1.57e-205 643.0
CMS2_k127_3647166_2 Glycosyl transferase family 1 - - - 3.685e-194 611.0
CMS2_k127_3647166_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 498.0
CMS2_k127_3647166_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 366.0
CMS2_k127_3647166_5 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 362.0
CMS2_k127_3647166_6 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000002007 211.0
CMS2_k127_3647166_7 Protein of unknown function DUF126 K09128 - - 0.00000000000000000000000000000000000000000000000000002768 190.0
CMS2_k127_3658031_0 Peptidase family M3 K08602 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 493.0
CMS2_k127_3658031_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 461.0
CMS2_k127_3658031_2 COG1651 Protein-disulfide isomerase K21990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008511 365.0
CMS2_k127_3658031_3 Belongs to the PdaD family K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 341.0
CMS2_k127_3658031_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002085 257.0
CMS2_k127_384792_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.0 1048.0
CMS2_k127_384792_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 1.339e-226 704.0
CMS2_k127_384792_10 - - - - 0.000000000000000000000003462 101.0
CMS2_k127_384792_11 - - - - 0.00000000000000008583 81.0
CMS2_k127_384792_12 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000002178 49.0
CMS2_k127_384792_13 - - - - 0.0007318 42.0
CMS2_k127_384792_2 Domain of unknown function (DUF373) K08975 - - 3.741e-196 616.0
CMS2_k127_384792_3 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005412 415.0
CMS2_k127_384792_4 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001431 277.0
CMS2_k127_384792_5 Translation initiation factor K03238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008371 269.0
CMS2_k127_384792_6 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000000000000000000000001223 221.0
CMS2_k127_384792_7 K homology RNA-binding domain K06961 - - 0.00000000000000000000000000000000000000000000000000000003452 201.0
CMS2_k127_384792_8 - - - - 0.0000000000000000000000000000000000000000000000000002269 190.0
CMS2_k127_384792_9 Protein of unknown function (DUF424) K09148 - - 0.00000000000000000000000000000000000002559 145.0
CMS2_k127_3897856_0 Lamin Tail Domain - - - 8.37e-202 644.0
CMS2_k127_3897856_1 Ribosome biogenesis protein, C-terminal K09140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000126 259.0
CMS2_k127_3897856_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000002964 207.0
CMS2_k127_3901126_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 383.0
CMS2_k127_3901126_1 - - - - 0.000000000000000000000893 97.0
CMS2_k127_3901126_2 - - - - 0.00000008472 55.0
CMS2_k127_3931113_0 Subtilase family - - - 0.0 1401.0
CMS2_k127_3931113_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 539.0
CMS2_k127_3931113_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 409.0
CMS2_k127_3931818_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 5.577e-284 875.0
CMS2_k127_3931818_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 422.0
CMS2_k127_3931818_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000004198 187.0
CMS2_k127_3931818_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000009687 151.0
CMS2_k127_3931818_5 - - - - 0.000004111 50.0
CMS2_k127_4027942_0 Methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 366.0
CMS2_k127_4027942_1 cytochrome-c peroxidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 358.0
CMS2_k127_4027942_2 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003728 258.0
CMS2_k127_4088365_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 7.208e-275 852.0
CMS2_k127_4088365_1 ATP-grasp domain K01295,K01439,K01921,K16181 - 3.4.17.11,3.5.1.18,6.3.2.4 3.353e-254 803.0
CMS2_k127_4088365_10 Ser thr protein kinase K07176 - - 0.00000000000000000000000000000000000000002715 162.0
CMS2_k127_4088365_11 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.00000000000000000000000000000000000002114 156.0
CMS2_k127_4088365_12 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000001095 114.0
CMS2_k127_4088365_13 - K00960 - 2.7.7.6 0.000000000000000000000114 96.0
CMS2_k127_4088365_14 - - - - 0.000000000000000000008002 93.0
CMS2_k127_4088365_15 AAA domain - - - 0.0000000000001251 71.0
CMS2_k127_4088365_2 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 595.0
CMS2_k127_4088365_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 593.0
CMS2_k127_4088365_4 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 524.0
CMS2_k127_4088365_5 COG1253 Hemolysins and related proteins containing CBS domains K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 427.0
CMS2_k127_4088365_6 N-formylglutamate amidohydrolase K01479 - 3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 391.0
CMS2_k127_4088365_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000004633 224.0
CMS2_k127_4088365_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000000000000004235 216.0
CMS2_k127_4088365_9 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000002502 195.0
CMS2_k127_4153530_0 NADH dehydrogenase K00337 - 1.6.5.3 7.188e-244 756.0
CMS2_k127_4153530_1 Belongs to the complex I 49 kDa subunit family K00333 - 1.6.5.3 6.093e-229 711.0
CMS2_k127_4153530_2 Belongs to the complex I 20 kDa subunit family K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 365.0
CMS2_k127_4153530_3 NADH ubiquinone oxidoreductase 27 kD subunit K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004615 271.0
CMS2_k127_4153530_4 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000008333 200.0
CMS2_k127_4190726_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K18604 - 2.1.3.15,6.4.1.2,6.4.1.3 1.507e-317 974.0
CMS2_k127_4190726_1 Carbamoyl-phosphate synthase L chain K18603 - 6.4.1.2,6.4.1.3 1.396e-284 878.0
CMS2_k127_4190726_10 4Fe-4S binding domain K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 336.0
CMS2_k127_4190726_11 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 289.0
CMS2_k127_4190726_12 NADH ubiquinone oxidoreductase 27 kD subunit K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000121 282.0
CMS2_k127_4190726_13 Biotin-requiring enzyme K18605 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001751 270.0
CMS2_k127_4190726_14 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 3 K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000004101 205.0
CMS2_k127_4190726_15 - - - - 0.000000000000000000000000000000000000000000000006263 173.0
CMS2_k127_4190726_16 NADH ubiquinone oxidoreductase subunit 11 or 4L (chain K) K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000000008036 172.0
CMS2_k127_4190726_17 - K03646 - - 0.0000000000000000000000000000000000000000584 160.0
CMS2_k127_4190726_18 acid phosphatase activity - - - 0.0000000000000000000000000000542 128.0
CMS2_k127_4190726_19 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000002306 99.0
CMS2_k127_4190726_2 NADH dehydrogenase K00337 - 1.6.5.3 6.059e-245 760.0
CMS2_k127_4190726_20 Protein of unknown function (DUF1059) - - - 0.000000000000000000003651 93.0
CMS2_k127_4190726_21 protein secretion by the type IV secretion system - - - 0.0000003 62.0
CMS2_k127_4190726_3 Belongs to the complex I 49 kDa subunit family K00333 - 1.6.5.3 1.469e-226 704.0
CMS2_k127_4190726_4 ATPase family associated with various cellular activities (AAA) K04800 - - 5.777e-210 656.0
CMS2_k127_4190726_5 - - - - 1.704e-199 625.0
CMS2_k127_4190726_6 oxidoreductase FAD NAD(P)-binding K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 462.0
CMS2_k127_4190726_7 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 459.0
CMS2_k127_4190726_8 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 449.0
CMS2_k127_4190726_9 Belongs to the complex I 20 kDa subunit family K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 364.0
CMS2_k127_4193659_0 COG1061 DNA or RNA helicases of superfamily II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 363.0
CMS2_k127_4193659_1 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 314.0
CMS2_k127_4193659_2 ribosomal protein K02866 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 289.0
CMS2_k127_4193659_3 - - - - 0.0000000000000000000000000000000000000000000000000002561 188.0
CMS2_k127_4193659_4 - - - - 0.00000000000000000000000000000000000000000001757 162.0
CMS2_k127_4193659_5 Sodium hydrogen exchanger K03455 - - 0.000000000000000006412 84.0
CMS2_k127_4193659_6 - - - - 0.0000000000003992 72.0
CMS2_k127_422434_0 Archaeal Nre, N-terminal - - - 3.878e-200 628.0
CMS2_k127_422434_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 517.0
CMS2_k127_422434_10 - - - - 0.00000000000000000000000000000000000000000000000000000000001919 207.0
CMS2_k127_422434_11 zinc finger - - - 0.000000000000000000000000000000000000000000000001818 175.0
CMS2_k127_422434_12 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000008584 113.0
CMS2_k127_422434_14 - - - - 0.00000000000006306 76.0
CMS2_k127_422434_2 geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 460.0
CMS2_k127_422434_3 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 443.0
CMS2_k127_422434_4 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 422.0
CMS2_k127_422434_5 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 401.0
CMS2_k127_422434_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009209 392.0
CMS2_k127_422434_7 DSBA oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 345.0
CMS2_k127_422434_8 Protein of unknown function DUF99 K09120 - - 0.00000000000000000000000000000000000000000000000000000000000000000004624 237.0
CMS2_k127_422434_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001568 224.0
CMS2_k127_4312769_0 PFAM Aldehyde dehydrogenase K00135,K18601 - 1.2.1.16,1.2.1.20,1.2.1.79 7.479e-210 655.0
CMS2_k127_4312769_1 Phosphate uptake regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 593.0
CMS2_k127_4312769_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 550.0
CMS2_k127_4312769_3 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006774 328.0
CMS2_k127_4312769_4 Patch-forming domain C2 of tRNA-guanine transglycosylase K07398 - - 0.000000000000000000000000000000000000000000000000000000000000000001007 230.0
CMS2_k127_4312769_5 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000004317 212.0
CMS2_k127_4312769_6 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000000000000000000000000000000000000002049 192.0
CMS2_k127_4312769_7 H subunit K02107 - - 0.000000000000000000000000000000000000000006055 156.0
CMS2_k127_4312769_8 - - - - 0.000000000000000000000000009597 110.0
CMS2_k127_4316467_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1324.0
CMS2_k127_4316467_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 509.0
CMS2_k127_4316467_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 380.0
CMS2_k127_4316467_3 - - - - 0.0000000000000000000000000000000000000000000000002145 177.0
CMS2_k127_4316467_4 - - - - 0.000000000000000000000000000000003518 130.0
CMS2_k127_4316467_5 Multicopper oxidase K00368 - 1.7.2.1 0.0000000000000000000000000002791 126.0
CMS2_k127_4316467_6 - - - - 0.000000000000000002529 89.0
CMS2_k127_4397019_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 6.398e-285 878.0
CMS2_k127_4397019_1 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 596.0
CMS2_k127_4397019_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 316.0
CMS2_k127_4397019_3 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 299.0
CMS2_k127_4397019_4 ribosomal protein K02907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001205 267.0
CMS2_k127_4397019_5 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000000000000000000005715 235.0
CMS2_k127_4397019_6 - - - - 0.000000000000000000000000000000000000000000000000000000583 196.0
CMS2_k127_4397019_7 Belongs to the archaeal adenylate kinase family K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000004054 173.0
CMS2_k127_4403803_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.5e-323 993.0
CMS2_k127_4403803_1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 - 3.3.1.1 4.101e-249 771.0
CMS2_k127_4403803_10 domain protein K20276 - - 0.0002224 51.0
CMS2_k127_4403803_2 PFAM tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 1.72e-238 743.0
CMS2_k127_4403803_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 406.0
CMS2_k127_4403803_4 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 380.0
CMS2_k127_4403803_5 Protein of unknown function (DUF726) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 336.0
CMS2_k127_4403803_6 Protein of unknown function (DUF432) K09149 - - 0.00000000000000000000000000000000000000000000000000000000000008914 221.0
CMS2_k127_4403803_7 Rieske-like [2Fe-2S] domain K05710 - - 0.00000000000000000000000000000000000000000000000000000005499 196.0
CMS2_k127_4403803_8 - - - - 0.00000000000000000000000000000000000000000005365 161.0
CMS2_k127_4403803_9 - - - - 0.00000000008688 73.0
CMS2_k127_4474894_0 MGS-like domain K01955 - 6.3.5.5 0.0 1862.0
CMS2_k127_4474894_1 carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 1.046e-215 673.0
CMS2_k127_4474894_2 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 380.0
CMS2_k127_4474894_3 ATP synthase (F/14-kDa) subunit K02122 - - 0.000000000000000000000000000000000000000000008673 163.0
CMS2_k127_4474894_4 - - - - 0.000000000000000000000000000000000000000000301 159.0
CMS2_k127_4474894_5 - - - - 0.000000000000000000000000000000000000000005877 155.0
CMS2_k127_4474894_6 - - - - 0.00000000000000000004951 91.0
CMS2_k127_4474894_7 MGS-like domain K01955 - 6.3.5.5 0.000002057 49.0
CMS2_k127_4484166_0 Zinc-binding dehydrogenase - - - 1.105e-213 666.0
CMS2_k127_4484166_1 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 1.814e-210 660.0
CMS2_k127_4484166_2 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 1.86e-204 644.0
CMS2_k127_4484166_3 ATP phosphoribosyltransferase K00765 - 2.4.2.17 1.792e-194 608.0
CMS2_k127_4484166_4 Glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 579.0
CMS2_k127_4484166_5 Diphthamide biosynthesis K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009467 566.0
CMS2_k127_4484166_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 564.0
CMS2_k127_4484166_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001506 275.0
CMS2_k127_4484166_8 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000000000000000000000000003122 156.0
CMS2_k127_4514331_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1636.0
CMS2_k127_4514331_1 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1161.0
CMS2_k127_4514331_10 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000000000000006378 119.0
CMS2_k127_4514331_11 - - - - 0.000000000000000000000000001764 111.0
CMS2_k127_4514331_12 - - - - 0.00000006238 55.0
CMS2_k127_4514331_2 Thiolase, N-terminal domain K00626 - 2.3.1.9 7.901e-233 722.0
CMS2_k127_4514331_3 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 458.0
CMS2_k127_4514331_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 416.0
CMS2_k127_4514331_5 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 404.0
CMS2_k127_4514331_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002414 263.0
CMS2_k127_4514331_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001974 235.0
CMS2_k127_4514331_8 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000000000000000000000000000000000000004279 161.0
CMS2_k127_4569801_0 adenylosuccinate lyase K01756 - 4.3.2.2 2.083e-250 777.0
CMS2_k127_4569801_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 546.0
CMS2_k127_4569801_2 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000007452 220.0
CMS2_k127_4569801_3 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000002158 135.0
CMS2_k127_4569801_4 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000000000000000337 129.0
CMS2_k127_4569801_5 serine-type endopeptidase activity - - - 0.0000000000000000000000000000003965 137.0
CMS2_k127_4569801_6 - - - - 0.00000000000000000000000006 121.0
CMS2_k127_4569801_7 sister chromatid segregation - - - 0.0000000000000225 85.0
CMS2_k127_4569801_8 - - - - 0.00000000000005291 84.0
CMS2_k127_4628365_0 membrane - - - 5.275e-204 641.0
CMS2_k127_4628365_1 serine-type endopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000008525 206.0
CMS2_k127_4628365_2 - - - - 0.000000000003169 76.0
CMS2_k127_4628365_3 microtubule nucleation K10389 GO:0000003,GO:0000070,GO:0000086,GO:0000166,GO:0000212,GO:0000226,GO:0000228,GO:0000242,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0000922,GO:0000930,GO:0000931,GO:0001882,GO:0001883,GO:0003002,GO:0003006,GO:0003674,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005768,GO:0005813,GO:0005814,GO:0005815,GO:0005819,GO:0005827,GO:0005829,GO:0005856,GO:0005874,GO:0005876,GO:0005881,GO:0005929,GO:0006810,GO:0006996,GO:0007010,GO:0007017,GO:0007020,GO:0007049,GO:0007051,GO:0007052,GO:0007056,GO:0007057,GO:0007059,GO:0007088,GO:0007097,GO:0007098,GO:0007127,GO:0007143,GO:0007144,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007308,GO:0007309,GO:0007310,GO:0007312,GO:0007346,GO:0007389,GO:0008150,GO:0008274,GO:0008275,GO:0008608,GO:0009266,GO:0009581,GO:0009582,GO:0009605,GO:0009628,GO:0009794,GO:0009798,GO:0009950,GO:0009953,GO:0009987,GO:0009994,GO:0010389,GO:0010457,GO:0010564,GO:0012505,GO:0015630,GO:0016043,GO:0016048,GO:0017076,GO:0019001,GO:0019953,GO:0021700,GO:0022402,GO:0022406,GO:0022412,GO:0022414,GO:0022607,GO:0030030,GO:0030031,GO:0030154,GO:0031023,GO:0031109,GO:0031252,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0032465,GO:0032501,GO:0032502,GO:0032504,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032954,GO:0032991,GO:0033043,GO:0034622,GO:0035639,GO:0036064,GO:0036094,GO:0042802,GO:0042995,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044441,GO:0044444,GO:0044446,GO:0044450,GO:0044463,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044782,GO:0044839,GO:0045132,GO:0045177,GO:0045995,GO:0046785,GO:0046907,GO:0048285,GO:0048468,GO:0048469,GO:0048477,GO:0048599,GO:0048609,GO:0048856,GO:0048869,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0051179,GO:0051225,GO:0051234,GO:0051235,GO:0051239,GO:0051258,GO:0051276,GO:0051302,GO:0051304,GO:0051306,GO:0051316,GO:0051321,GO:0051606,GO:0051640,GO:0051641,GO:0051642,GO:0051647,GO:0051649,GO:0051651,GO:0051656,GO:0051657,GO:0051661,GO:0051663,GO:0051704,GO:0051726,GO:0051783,GO:0055037,GO:0060271,GO:0061842,GO:0061982,GO:0065003,GO:0065007,GO:0065008,GO:0070013,GO:0070925,GO:0071840,GO:0072687,GO:0090306,GO:0097159,GO:0097367,GO:0097435,GO:0097708,GO:0097711,GO:0097730,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0099513,GO:0120025,GO:0120031,GO:0120036,GO:0120038,GO:0140013,GO:0140014,GO:0140056,GO:1901265,GO:1901363,GO:1901987,GO:1901990,GO:1902412,GO:1902749,GO:1902850,GO:1903046,GO:1903047,GO:1903436,GO:2000026 - 0.000000000003335 79.0
CMS2_k127_4628365_4 - - - - 0.00000000001885 74.0
CMS2_k127_4628365_5 - - - - 0.00000001546 64.0
CMS2_k127_4663528_0 TIGRFAM poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 - - 1.469e-218 679.0
CMS2_k127_4663528_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 540.0
CMS2_k127_4663528_10 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000001815 208.0
CMS2_k127_4663528_11 CoA binding domain K06929 - - 0.0000000000000000000000000000000000000000000000000000000002467 205.0
CMS2_k127_4663528_12 - - - - 0.00000000000000000000000000000000000000000000000000000003019 198.0
CMS2_k127_4663528_13 phosphoribosyltransferase K07101 - - 0.0000000000000000000000000000000000000000000000000004026 188.0
CMS2_k127_4663528_14 - - - - 0.000000000000000000000000000000000001112 139.0
CMS2_k127_4663528_15 - - - - 0.00000000000000000000000000000001711 128.0
CMS2_k127_4663528_16 Male sterility protein K00091,K19997 - 1.1.1.219,5.1.3.26 0.0000000000000000000000000085 121.0
CMS2_k127_4663528_17 - - - - 0.0000000000000000000005813 99.0
CMS2_k127_4663528_2 biotin-(Acetyl-CoA-carboxylase) ligase K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 489.0
CMS2_k127_4663528_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 384.0
CMS2_k127_4663528_4 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 315.0
CMS2_k127_4663528_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002787 269.0
CMS2_k127_4663528_6 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000004749 238.0
CMS2_k127_4663528_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001172 223.0
CMS2_k127_4663528_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001791 224.0
CMS2_k127_4663528_9 COG2002 Regulators of stationary sporulation gene expression - - - 0.0000000000000000000000000000000000000000000000000000000000000002419 222.0
CMS2_k127_514056_0 DEAD/H associated K03724 - - 0.0 1089.0
CMS2_k127_514056_1 S-adenosylmethionine synthetase K00789 - 2.5.1.6 6.589e-232 720.0
CMS2_k127_514056_2 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 574.0
CMS2_k127_514056_3 Cobalamin synthesis G C-terminus K02189 - 3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007468 515.0
CMS2_k127_514056_4 Cobalt chelatase (CbiK) K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 414.0
CMS2_k127_514056_5 RecA RadA K04482,K04483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 296.0
CMS2_k127_514056_6 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.00000000000000000000000000000000000000000000000000001432 195.0
CMS2_k127_514056_7 snRNP Sm proteins K04796 - - 0.00000000000000000000000000000000000001086 145.0
CMS2_k127_514056_8 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000001701 126.0
CMS2_k127_5185429_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 2.544e-198 624.0
CMS2_k127_5185429_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 377.0
CMS2_k127_5185429_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000004843 93.0
CMS2_k127_5212894_0 Glycosyl transferase family group 2 - - - 0.0 1159.0
CMS2_k127_5212894_1 3-isopropylmalate dehydratase, large subunit K01703 - 4.2.1.33,4.2.1.35 1.482e-276 854.0
CMS2_k127_5212894_10 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 449.0
CMS2_k127_5212894_11 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 418.0
CMS2_k127_5212894_12 ERCC4 domain K10848 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 394.0
CMS2_k127_5212894_13 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 387.0
CMS2_k127_5212894_14 F420-0:Gamma-glutamyl ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 383.0
CMS2_k127_5212894_15 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 383.0
CMS2_k127_5212894_16 PFAM Nucleotidyl transferase K00966,K03430 - 2.6.1.37,2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 377.0
CMS2_k127_5212894_17 DNA-directed RNA polymerase, alpha subunit 40 kD subunit K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 363.0
CMS2_k127_5212894_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 340.0
CMS2_k127_5212894_19 3-isopropylmalate dehydratase, small subunit K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 307.0
CMS2_k127_5212894_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 7.607e-251 777.0
CMS2_k127_5212894_20 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001181 278.0
CMS2_k127_5212894_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008539 266.0
CMS2_k127_5212894_22 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000471 262.0
CMS2_k127_5212894_23 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000006438 235.0
CMS2_k127_5212894_24 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000007255 222.0
CMS2_k127_5212894_25 TIGRFAM CRISPR-associated protein Cas4 K03466,K07464,K15342,K19465 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000000000000008484 222.0
CMS2_k127_5212894_26 - - - - 0.0000000000000000000000000000000000000000000000000002534 186.0
CMS2_k127_5212894_27 - - - - 0.0000000000000000000000000000000000000000000000001676 177.0
CMS2_k127_5212894_28 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000000000000000000000000000000001156 156.0
CMS2_k127_5212894_29 Ribosomal L37ae protein family K02921 - - 0.000000000000000000000000000000001575 130.0
CMS2_k127_5212894_3 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 9.337e-241 750.0
CMS2_k127_5212894_30 PIN domain of ribonuclease K07060 - - 0.0000000000000000000000000000148 123.0
CMS2_k127_5212894_31 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000002354 89.0
CMS2_k127_5212894_4 Sodium hydrogen exchanger K03455 - - 8.858e-221 691.0
CMS2_k127_5212894_5 Required for chromosome condensation and partitioning - - - 1.103e-218 689.0
CMS2_k127_5212894_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 568.0
CMS2_k127_5212894_7 ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 553.0
CMS2_k127_5212894_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009284 467.0
CMS2_k127_5212894_9 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 454.0
CMS2_k127_5215076_0 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 529.0
CMS2_k127_5215076_1 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 352.0
CMS2_k127_5215076_2 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 282.0
CMS2_k127_5219355_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 3.159e-278 861.0
CMS2_k127_5219355_1 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 305.0
CMS2_k127_5219355_2 Binds to the 23S rRNA K02885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001402 258.0
CMS2_k127_5219355_3 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000006102 175.0
CMS2_k127_5219355_4 ribosomal protein K02912 - - 0.00000000000000000000000000000000000008195 146.0
CMS2_k127_5219355_5 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000001803 97.0
CMS2_k127_5219355_6 Belongs to the peptidase S8 family K14647 - - 0.00000000004075 66.0
CMS2_k127_5233011_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0 1048.0
CMS2_k127_5233011_1 Beta propeller domain - - - 0.0 1043.0
CMS2_k127_5233011_10 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 362.0
CMS2_k127_5233011_11 Uracil-DNA glycosylase K21929 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 356.0
CMS2_k127_5233011_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 358.0
CMS2_k127_5233011_13 Ribose 5-phosphate isomerase K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 347.0
CMS2_k127_5233011_14 Signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 294.0
CMS2_k127_5233011_15 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 287.0
CMS2_k127_5233011_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002657 270.0
CMS2_k127_5233011_17 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000001169 246.0
CMS2_k127_5233011_18 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001435 242.0
CMS2_k127_5233011_19 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000000000000000000000000334 236.0
CMS2_k127_5233011_2 Amidohydrolase family K01464 - 3.5.2.2 4.795e-247 767.0
CMS2_k127_5233011_20 regulatory protein, arsR - - - 0.00000000000000000000000000000000000000000000000000000000000000000007213 240.0
CMS2_k127_5233011_21 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000008851 230.0
CMS2_k127_5233011_22 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000000000000000000000000000000000002417 225.0
CMS2_k127_5233011_23 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000002722 233.0
CMS2_k127_5233011_24 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000386 227.0
CMS2_k127_5233011_25 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000000000000000000000000000944 213.0
CMS2_k127_5233011_26 zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000006119 211.0
CMS2_k127_5233011_27 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001103 214.0
CMS2_k127_5233011_28 snRNP Sm proteins K04796 - - 0.0000000000000000000000000000000000001539 141.0
CMS2_k127_5233011_29 Binds to the 23S rRNA K02896 - - 0.0000000000000000000000000000000001041 132.0
CMS2_k127_5233011_3 Belongs to the phosphohexose mutase family K15778 - 5.4.2.2,5.4.2.8 3.847e-228 713.0
CMS2_k127_5233011_30 Binds to the 23S rRNA K02922 - - 0.00000000000000000000000000000003358 124.0
CMS2_k127_5233011_31 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000000000001682 123.0
CMS2_k127_5233011_32 cheY-homologous receiver domain - - - 0.000000000000000000000004867 105.0
CMS2_k127_5233011_4 Glucose sorbosone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 558.0
CMS2_k127_5233011_5 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 492.0
CMS2_k127_5233011_6 Formyl transferase K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 485.0
CMS2_k127_5233011_7 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 473.0
CMS2_k127_5233011_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 391.0
CMS2_k127_5233011_9 Zinc finger domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 365.0
CMS2_k127_5245332_0 AIPR protein - - - 0.0 1027.0
CMS2_k127_5245332_1 Belongs to the RtcB family K14415 - 6.5.1.3 1.974e-287 886.0
CMS2_k127_5245332_10 - - - - 0.0000000000000000000000000000000000365 136.0
CMS2_k127_5245332_11 zinc finger - - - 0.000000000000000000002817 98.0
CMS2_k127_5245332_12 - - - - 0.00000000000000000001161 96.0
CMS2_k127_5245332_13 - - - - 0.0000000000000000403 82.0
CMS2_k127_5245332_14 - - - - 0.000000000000002055 78.0
CMS2_k127_5245332_15 - - - - 0.00000000000000278 81.0
CMS2_k127_5245332_16 - - - - 0.00000001519 59.0
CMS2_k127_5245332_17 - - - - 0.000004436 49.0
CMS2_k127_5245332_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - - 2.114e-214 674.0
CMS2_k127_5245332_3 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 371.0
CMS2_k127_5245332_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 317.0
CMS2_k127_5245332_5 Located on the platform of the 30S subunit K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001922 270.0
CMS2_k127_5245332_6 PFAM Chromatin associated protein KTI12 K00860,K10837 - 2.7.1.164,2.7.1.25 0.000000000000000000000000000000000000000000000002528 177.0
CMS2_k127_5245332_7 - - - - 0.0000000000000000000000000000000000000000000007408 168.0
CMS2_k127_5245332_8 Winged helix-turn-helix - - - 0.000000000000000000000000000000000000000000008192 164.0
CMS2_k127_5245332_9 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006725,GO:0006732,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.0000000000000000000000000000000000000001036 162.0
CMS2_k127_5246686_0 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis K07332 - - 7.186e-194 617.0
CMS2_k127_5246686_1 ATPase associated with various cellular activities, AAA_5 K03924,K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 462.0
CMS2_k127_5246686_10 - - - - 0.0000000000002637 77.0
CMS2_k127_5246686_2 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 289.0
CMS2_k127_5246686_3 von Willebrand factor, type A K04043,K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006607 286.0
CMS2_k127_5246686_4 TIGRFAM archaeal flagellin N-terminal-like domain - - - 0.000000000000000000000000000000000000000000000000000000002014 207.0
CMS2_k127_5246686_5 TIGRFAM archaeal flagellin N-terminal-like domain - - - 0.0000000000000000000000001437 124.0
CMS2_k127_5246686_6 Archaeal flagellar protein F K07329 - - 0.0000000000000000000000002845 110.0
CMS2_k127_5246686_8 Histidine kinase - - - 0.000000000000000000001103 105.0
CMS2_k127_5304971_0 AAA domain (Cdc48 subfamily) - - - 1.379e-227 707.0
CMS2_k127_5304971_1 - - - - 0.00000000000000000000000000000000002163 141.0
CMS2_k127_5304971_2 conserved protein implicated in secretion - - - 0.000000000000000000000000000000004556 130.0
CMS2_k127_5304971_3 carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000001177 62.0
CMS2_k127_5305054_0 Belongs to the MCM family K10726 - - 0.0 1262.0
CMS2_k127_5305054_1 histidyl-tRNA synthetase K01892 - 6.1.1.21 2.672e-213 668.0
CMS2_k127_5305054_10 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.00000000000000000000000000000003234 126.0
CMS2_k127_5305054_12 - - - - 0.0000000000002775 80.0
CMS2_k127_5305054_13 - - - - 0.00000000171 64.0
CMS2_k127_5305054_2 Replication factor C K04801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 531.0
CMS2_k127_5305054_3 PFAM 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 303.0
CMS2_k127_5305054_4 PFAM 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 281.0
CMS2_k127_5305054_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000009362 185.0
CMS2_k127_5305054_6 GINS complex protein K09723 - - 0.00000000000000000000000000000000000000000001859 167.0
CMS2_k127_5305054_7 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 GO:0000460,GO:0000470,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030684,GO:0030687,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042273,GO:0043021,GO:0043023,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1902626,GO:1990904 - 0.0000000000000000000000000000000000000000004589 166.0
CMS2_k127_5305054_9 COG1525 Micrococcal nuclease (thermonuclease) homologs K01174 - 3.1.31.1 0.0000000000000000000000000000000000008347 146.0
CMS2_k127_5346914_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 5.129e-315 974.0
CMS2_k127_5346914_1 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 281.0
CMS2_k127_5346914_2 ribosomal small subunit binding - - - 0.00000000000000000000000000000000000000000000000000000000001535 210.0
CMS2_k127_5346914_3 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000001761 160.0
CMS2_k127_5354315_0 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000562 558.0
CMS2_k127_5354315_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 460.0
CMS2_k127_5354315_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005157 258.0
CMS2_k127_5354315_3 Belongs to the glycosyl hydrolase 18 family - - - 0.000000000000000000000000000000000000000000000008018 193.0
CMS2_k127_5354315_4 Pfam:DUF385 - - - 0.0000000000000000000000000000000008315 132.0
CMS2_k127_5354315_5 COG3291 FOG PKD repeat - - - 0.000000000000006235 89.0
CMS2_k127_5354315_6 Exonuclease - - - 0.0000351 54.0
CMS2_k127_5383701_0 Binds the lower part of the 30S subunit head K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 417.0
CMS2_k127_5383701_1 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 391.0
CMS2_k127_5383701_2 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 282.0
CMS2_k127_5383701_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009127 261.0
CMS2_k127_5383701_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000000000000000000000001207 228.0
CMS2_k127_5383701_5 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000000000000000000001233 192.0
CMS2_k127_5383701_6 Located at the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000000000000009947 190.0
CMS2_k127_5383701_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000002925 186.0
CMS2_k127_5383701_8 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000000000001763 109.0
CMS2_k127_5383701_9 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.0000000000000000000000003048 109.0
CMS2_k127_562085_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1362.0
CMS2_k127_562085_1 Heat shock 70 kDa protein K04043 - - 0.0 1024.0
CMS2_k127_562085_10 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 453.0
CMS2_k127_562085_11 Archaeal transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 377.0
CMS2_k127_562085_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 350.0
CMS2_k127_562085_13 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007365 279.0
CMS2_k127_562085_14 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001414 246.0
CMS2_k127_562085_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004938 237.0
CMS2_k127_562085_16 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000000000000000000000003482 225.0
CMS2_k127_562085_17 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000000000000000002715 160.0
CMS2_k127_562085_18 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000000000000000000000001712 148.0
CMS2_k127_562085_19 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000002028 141.0
CMS2_k127_562085_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 1.294e-280 874.0
CMS2_k127_562085_20 - - - - 0.0000000000000000000000001438 107.0
CMS2_k127_562085_21 - - - - 0.000000000000000003103 84.0
CMS2_k127_562085_22 - - - - 0.00000000000001463 83.0
CMS2_k127_562085_23 - - - - 0.00000000001041 75.0
CMS2_k127_562085_24 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000002465 49.0
CMS2_k127_562085_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - - 4.145e-219 683.0
CMS2_k127_562085_4 Peptidase family M50 - - - 2.895e-217 679.0
CMS2_k127_562085_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 6.509e-212 664.0
CMS2_k127_562085_6 DnaJ central domain K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 580.0
CMS2_k127_562085_7 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 552.0
CMS2_k127_562085_8 PP-loop family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006943 520.0
CMS2_k127_562085_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 502.0
CMS2_k127_5646616_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.272e-256 807.0
CMS2_k127_5646616_1 Mg2 transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006794 544.0
CMS2_k127_5646616_2 RNA methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 375.0
CMS2_k127_5646616_3 Methyltransferase type 11 K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 319.0
CMS2_k127_5646616_4 Rieske 2Fe-2S K05710 - - 0.00000000000000000000000000000000000000000000000000001978 188.0
CMS2_k127_5646616_5 - - - - 0.0000000000000000000000000000000000000000000000000001881 186.0
CMS2_k127_5646616_6 copper ion binding - - - 0.000000000000000000000000000000000000000000000000003665 185.0
CMS2_k127_5646616_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000001779 175.0
CMS2_k127_5646616_8 Belongs to the UPF0147 family K09721 - - 0.0000000000000000000000000000000000000003788 149.0
CMS2_k127_5646616_9 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000003319 132.0
CMS2_k127_5670360_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 571.0
CMS2_k127_5670360_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005078 273.0
CMS2_k127_5670360_2 Protein of unknown function (DUF354) K09726 - - 0.00000000000000000000000000000000000000000000000000000000000000000005543 239.0
CMS2_k127_5758486_0 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 287.0
CMS2_k127_5758486_1 conserved protein (DUF2299) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001099 233.0
CMS2_k127_5758486_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000003269 220.0
CMS2_k127_5758486_3 - - - - 0.000000000000000000000000000000000000000000001124 166.0
CMS2_k127_5758486_4 - - - - 0.000000000000000000000000000000000000000001583 156.0
CMS2_k127_5758486_5 ribosomal protein S14 K02954 - - 0.00000000000000000000000000000003082 126.0
CMS2_k127_5758486_6 - - - - 0.0000000000000000000000000007058 114.0
CMS2_k127_5771139_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 586.0
CMS2_k127_5771139_1 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009538 344.0
CMS2_k127_5771139_2 Belongs to the SUI1 family K03113 - - 0.00000000000000000000000000000000000000000000000000000003914 196.0
CMS2_k127_5771139_3 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) K07143 - - 0.000000000000000000000000000000000000000002208 157.0
CMS2_k127_5771139_4 Sec61beta family - - - 0.00000000000000000000104 94.0
CMS2_k127_5771139_5 Guanylyl transferase CofC like K14941 - 2.7.7.68 0.0000000000000000000575 90.0
CMS2_k127_5867308_0 Radical SAM K11781 - 2.5.1.77 5.947e-227 707.0
CMS2_k127_5867308_1 Radical SAM K11780 - 2.5.1.77 1.163e-201 632.0
CMS2_k127_5867308_10 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000001255 130.0
CMS2_k127_5867308_12 - - - - 0.0000000000000000000000001335 107.0
CMS2_k127_5867308_13 metalloendopeptidase activity - - - 0.000000000000000003202 86.0
CMS2_k127_5867308_2 PFAM Glycosyl transferase family 2 K07011,K11936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 602.0
CMS2_k127_5867308_3 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009556 597.0
CMS2_k127_5867308_4 Lamin Tail Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 571.0
CMS2_k127_5867308_5 Protein of unknown function (DUF1512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 560.0
CMS2_k127_5867308_6 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 533.0
CMS2_k127_5867308_7 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 345.0
CMS2_k127_5867308_8 Putative tRNA binding domain K06878 - - 0.000000000000000000000000000000000000000000000000000000009069 199.0
CMS2_k127_5867308_9 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000003068 201.0
CMS2_k127_5889568_0 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 403.0
CMS2_k127_5889568_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 350.0
CMS2_k127_5889568_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000001092 220.0
CMS2_k127_5889568_3 tRNA pseudouridine synthase K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000002479 192.0
CMS2_k127_5889568_4 - - - - 0.0000000000000000000000000000001972 126.0
CMS2_k127_5889568_5 - - - - 0.0000000000000000000000000013 113.0
CMS2_k127_5889568_6 - - - - 0.000000000000000648 78.0
CMS2_k127_5898018_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1897.0
CMS2_k127_5898018_1 PFAM TCP-1 cpn60 chaperonin family K22447 - - 5e-324 998.0
CMS2_k127_5898018_10 - - - - 0.00000000000000000000000001856 112.0
CMS2_k127_5898018_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000005983 72.0
CMS2_k127_5898018_2 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 2.442e-315 966.0
CMS2_k127_5898018_3 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.466e-271 839.0
CMS2_k127_5898018_4 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 437.0
CMS2_k127_5898018_5 protein conserved in archaea K09723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002756 262.0
CMS2_k127_5898018_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005562 257.0
CMS2_k127_5898018_7 - - - - 0.000000000000000000000000000000000000000000000000000000001027 202.0
CMS2_k127_5898018_8 - - - - 0.000000000000000000000000000000000000000000000000006451 181.0
CMS2_k127_5898018_9 zinc finger - - - 0.000000000000000000000000000000007675 128.0
CMS2_k127_5912908_0 TIGRFAM 2-methylcitrate synthase citrate synthase II K01647 - 2.3.3.1 3.634e-219 683.0
CMS2_k127_5912908_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 5.418e-199 633.0
CMS2_k127_5912908_2 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 580.0
CMS2_k127_5912908_3 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001014 254.0
CMS2_k127_5912908_4 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000001167 168.0
CMS2_k127_5912908_5 - - - - 0.0000000000000000000000000000000000005814 142.0
CMS2_k127_5912908_6 - - - - 0.0000000000000000000000000000002693 126.0
CMS2_k127_5912908_8 Predicted membrane protein (DUF2061) - - - 0.000009181 51.0
CMS2_k127_5917831_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0 1035.0
CMS2_k127_5917831_1 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 585.0
CMS2_k127_5917831_2 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 469.0
CMS2_k127_5917831_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 336.0
CMS2_k127_5917831_4 acetolactate synthase, small K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 292.0
CMS2_k127_5917831_5 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000004172 216.0
CMS2_k127_5926581_0 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 - 2.1.1.260 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 310.0
CMS2_k127_5926581_1 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 280.0
CMS2_k127_5926581_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004804 246.0
CMS2_k127_5926581_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.000000000000000000000000000000000000000000002271 165.0
CMS2_k127_5926581_4 PFAM Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000002123 147.0
CMS2_k127_5926581_5 Belongs to the PDCD5 family K06875 - - 0.000000000000000000000000000000401 124.0
CMS2_k127_6031782_0 Cytochrome b subunit of the bc complex K00412 - - 1.747e-278 861.0
CMS2_k127_6031782_1 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 2.099e-237 737.0
CMS2_k127_6031782_2 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 386.0
CMS2_k127_6031782_3 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002416 239.0
CMS2_k127_6031782_4 NADH ubiquinone oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000286 226.0
CMS2_k127_6031782_5 - - - - 0.0000000000000000000000000000000000000000000000000000000006362 203.0
CMS2_k127_6031782_6 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 0.00000000000000000000000000000000001786 136.0
CMS2_k127_6031782_7 - - - - 0.000000000000000000000000000000001292 130.0
CMS2_k127_6199813_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 0.0 1046.0
CMS2_k127_6199813_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.24e-322 990.0
CMS2_k127_6199813_10 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000001592 162.0
CMS2_k127_6199813_11 - - - - 0.0000000000000000000000000000000000000008171 149.0
CMS2_k127_6199813_13 - - - - 0.0001843 46.0
CMS2_k127_6199813_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 4.464e-238 738.0
CMS2_k127_6199813_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 555.0
CMS2_k127_6199813_4 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 496.0
CMS2_k127_6199813_5 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 437.0
CMS2_k127_6199813_6 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 426.0
CMS2_k127_6199813_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 310.0
CMS2_k127_6199813_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000003013 220.0
CMS2_k127_6199813_9 ribosomal protein K02976 - - 0.000000000000000000000000000000000000000000000000000002216 191.0
CMS2_k127_6200430_0 Uncharacterised protein family (UPF0182) K09118 - - 0.0 1619.0
CMS2_k127_6200430_1 Initiation factor K03242 - - 5.644e-243 753.0
CMS2_k127_6200430_10 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.00000000000000000000000000000000000000000000000000000000000001784 216.0
CMS2_k127_6200430_11 - - - - 0.00000000000000000000000002631 108.0
CMS2_k127_6200430_12 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000000000000000005707 102.0
CMS2_k127_6200430_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 1.783e-201 636.0
CMS2_k127_6200430_3 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 593.0
CMS2_k127_6200430_4 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 440.0
CMS2_k127_6200430_5 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009453 445.0
CMS2_k127_6200430_6 Translation initiation factor 2, alpha subunit K03237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 433.0
CMS2_k127_6200430_7 ATP corrinoid adenosyltransferase K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 291.0
CMS2_k127_6200430_8 glutamine amidotransferase K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000004029 247.0
CMS2_k127_6200430_9 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000001412 223.0
CMS2_k127_6241042_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) - - - 9.336e-260 802.0
CMS2_k127_6241042_1 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 582.0
CMS2_k127_6241042_2 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 517.0
CMS2_k127_6241042_3 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 327.0
CMS2_k127_6241042_4 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 296.0
CMS2_k127_6241042_5 Transcription elongation factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002614 293.0
CMS2_k127_6241042_6 - - - - 0.000000000000000000000000000000000000000000000000000000000006344 209.0
CMS2_k127_6241042_7 - - - - 0.000000000000000000000000000000000000000002856 158.0
CMS2_k127_6241042_8 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.000000000000000000000000000000000006184 143.0
CMS2_k127_6241042_9 - - - - 0.00000000000000000000007063 100.0
CMS2_k127_6280888_0 Succinyl-CoA ligase like flavodoxin domain K18593 - - 0.0 1266.0
CMS2_k127_6280888_1 Vinylacetyl-CoA Delta-isomerase K14534 - 4.2.1.120,5.3.3.3 2.175e-318 977.0
CMS2_k127_6280888_10 - - - - 0.00000000000000000000000000000000000000046 149.0
CMS2_k127_6280888_11 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000002479 150.0
CMS2_k127_6280888_12 - - - - 0.00000000000000000000000000000000003801 135.0
CMS2_k127_6280888_13 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000002585 126.0
CMS2_k127_6280888_14 TIGRFAM Glutaredoxin-like domain protein - - - 0.000000000000000000000000002168 112.0
CMS2_k127_6280888_15 - - - - 0.0000000000000000002697 92.0
CMS2_k127_6280888_16 YHS domain - - - 0.000000000000001614 76.0
CMS2_k127_6280888_17 - - - - 0.000000001274 60.0
CMS2_k127_6280888_18 PFAM Protein kinase domain - - - 0.0000001403 58.0
CMS2_k127_6280888_19 Reverse transcriptase-like K03469 - 3.1.26.4 0.000003599 53.0
CMS2_k127_6280888_2 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 521.0
CMS2_k127_6280888_3 cytochrome c biogenesis protein K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 420.0
CMS2_k127_6280888_4 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000115 221.0
CMS2_k127_6280888_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000001335 214.0
CMS2_k127_6280888_6 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000003258 207.0
CMS2_k127_6280888_7 - - - - 0.000000000000000000000000000000000000000000000000000001505 195.0
CMS2_k127_6280888_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000003818 194.0
CMS2_k127_6280888_9 Bacterial regulatory protein, arsR family - - - 0.0000000000000000000000000000000000000000000004242 167.0
CMS2_k127_6314695_0 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 381.0
CMS2_k127_6314695_1 COG0607 Rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000866 262.0
CMS2_k127_6314695_2 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000002387 237.0
CMS2_k127_6314695_3 COG1525 Micrococcal nuclease (thermonuclease) homologs K01174 - 3.1.31.1 0.000000000000000000000000000000000000000000000000000000000000001063 226.0
CMS2_k127_6339416_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 1.073e-207 655.0
CMS2_k127_6339416_1 Belongs to the peptidase S8 family K14647 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 529.0
CMS2_k127_6339416_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006413 398.0
CMS2_k127_6339416_3 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000004755 200.0
CMS2_k127_6339416_4 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000000000000000000000000000000000000000000001693 182.0
CMS2_k127_6373135_0 PFAM Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 4.229e-195 612.0
CMS2_k127_6373135_1 factor TFIIB K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 570.0
CMS2_k127_6373135_10 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000002542 238.0
CMS2_k127_6373135_11 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004922 233.0
CMS2_k127_6373135_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000003654 217.0
CMS2_k127_6373135_13 Ribosomal protein S8e K02995 - - 0.00000000000000000000000000000000000000000000000000000000000007273 214.0
CMS2_k127_6373135_14 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000000000000000000000000000000004845 207.0
CMS2_k127_6373135_15 SRP19 protein K03105 - - 0.0000000000000000000000000000000000000000000003405 168.0
CMS2_k127_6373135_16 - - - - 0.000000000000000000000000000000000000000000003658 165.0
CMS2_k127_6373135_17 RNA-binding protein involved in rRNA processing K07569 - - 0.000000000000000000000000000000003525 129.0
CMS2_k127_6373135_18 Cold shock protein domain K03704 - - 0.0000000000000000000000000000002629 123.0
CMS2_k127_6373135_19 DUF167 K09131 - - 0.000000000000000002371 86.0
CMS2_k127_6373135_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 566.0
CMS2_k127_6373135_20 - - - - 0.00000002794 56.0
CMS2_k127_6373135_21 response regulator, receiver K03413 - - 0.00000003625 54.0
CMS2_k127_6373135_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 548.0
CMS2_k127_6373135_4 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 516.0
CMS2_k127_6373135_5 FeS assembly ATPase SufC K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 480.0
CMS2_k127_6373135_6 chromosome segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 363.0
CMS2_k127_6373135_7 Chlorite dismutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 361.0
CMS2_k127_6373135_8 segregation and condensation protein K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003486 312.0
CMS2_k127_6373135_9 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 298.0
CMS2_k127_642390_0 Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 556.0
CMS2_k127_642390_1 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000008133 263.0
CMS2_k127_642390_2 HD domain K07023 - - 0.00000000000000000000000000000000000000000000002609 174.0
CMS2_k127_6459481_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 1.189e-246 764.0
CMS2_k127_6459481_1 Phosphoglycerate kinase K00927 - 2.7.2.3 7.125e-233 724.0
CMS2_k127_6459481_2 FeS assembly protein SufD K09014,K09015 - - 4.058e-201 630.0
CMS2_k127_6459481_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 331.0
CMS2_k127_6459481_4 SUF system FeS assembly protein K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008978 264.0
CMS2_k127_6459481_5 of nitrite reductase and ring-hydroxylating K05710 - - 0.00000000000000000000000000000000000000000000006688 171.0
CMS2_k127_6459481_6 - - - - 0.00000000000000000000000000000000000000000003851 162.0
CMS2_k127_6459481_7 - - - - 0.00000000000000000000000000000005079 128.0
CMS2_k127_6486979_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 4.368e-266 824.0
CMS2_k127_6486979_1 GTPase of unknown function C-terminal K06942 - - 3.96e-212 664.0
CMS2_k127_6486979_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 580.0
CMS2_k127_6486979_3 Mn2 -dependent serine threonine protein kinase K08851 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 309.0
CMS2_k127_6486979_4 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000001926 196.0
CMS2_k127_6486979_5 - - - - 0.0000000000000000000000000000000000000000000000004466 177.0
CMS2_k127_6500050_0 fumarate reductase flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.0 1057.0
CMS2_k127_6500050_1 argininosuccinate lyase K01755 - 4.3.2.1 3.594e-240 749.0
CMS2_k127_6500050_10 COG4618 ABC-type protease lipase transport system, ATPase and permease components - - - 0.00000001747 56.0
CMS2_k127_6500050_2 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 539.0
CMS2_k127_6500050_3 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 468.0
CMS2_k127_6500050_4 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007642 283.0
CMS2_k127_6500050_5 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006675 258.0
CMS2_k127_6500050_6 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000808 228.0
CMS2_k127_6500050_7 ester cyclase K06893 - - 0.0000000000000000000000000000000000000000000000000000000000000005529 220.0
CMS2_k127_6500050_8 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000000000000000000000000000000000000000000000004442 203.0
CMS2_k127_6500050_9 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000000000000000000000000001118 184.0
CMS2_k127_6595749_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 380.0
CMS2_k127_6595749_1 riboflavin synthase, alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 342.0
CMS2_k127_6595749_2 Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity K08096 - 3.5.4.29 0.0000000000000000000000000000000000000000000000000000000000000000002354 231.0
CMS2_k127_6595749_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000003917 216.0
CMS2_k127_6595749_4 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000000000000000002822 128.0
CMS2_k127_6847136_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 304.0
CMS2_k127_6847136_1 Participates in transcription termination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 285.0
CMS2_k127_6847136_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000006399 224.0
CMS2_k127_6847136_3 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.000000000000000000000000000000000000000000000009283 172.0
CMS2_k127_6847136_4 Belongs to the universal ribosomal protein uS12 family K02973 GO:0000462,GO:0001666,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006355,GO:0006357,GO:0006364,GO:0006396,GO:0006412,GO:0006450,GO:0006518,GO:0006606,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0006950,GO:0008104,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0015031,GO:0015833,GO:0015935,GO:0016070,GO:0016072,GO:0017038,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0023051,GO:0023056,GO:0030490,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0033036,GO:0033365,GO:0033554,GO:0034470,GO:0034504,GO:0034613,GO:0034641,GO:0034645,GO:0034660,GO:0036293,GO:0036294,GO:0042221,GO:0042254,GO:0042274,GO:0042886,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045184,GO:0045893,GO:0045935,GO:0045944,GO:0046483,GO:0046907,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051169,GO:0051170,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051252,GO:0051254,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0065008,GO:0070482,GO:0070727,GO:0070887,GO:0071453,GO:0071456,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990904,GO:2000112,GO:2000638,GO:2000640,GO:2001141 - 0.00000000000000000000000000000000000001978 149.0
CMS2_k127_6968212_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 - - 1.64e-269 832.0
CMS2_k127_6968212_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 1.206e-205 641.0
CMS2_k127_6968212_2 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000000000001862 211.0
CMS2_k127_6968212_3 - - - - 0.0000000000000000000000000000000000000002477 149.0
CMS2_k127_6968212_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.0000000000000000000000000000001354 124.0
CMS2_k127_6968212_5 Zinc finger, C2H2 type - - - 0.00000000000000000000000268 103.0
CMS2_k127_7010624_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 6.547e-285 879.0
CMS2_k127_7010624_1 DHHA1 domain K07463 - - 6.655e-268 829.0
CMS2_k127_7010624_10 - - - - 0.00000000000000000000000000000000000000000000000000000009582 194.0
CMS2_k127_7010624_11 - - - - 0.0000000000000000000000000000000000000000000000000000001535 196.0
CMS2_k127_7010624_12 RNA binding K07581 - - 0.0000000000000000000000000000000000000000000001462 171.0
CMS2_k127_7010624_13 - - - - 0.0000000000000000000000000000000000000000000002367 169.0
CMS2_k127_7010624_14 - - - - 0.000000000000000000000000000000000000000000004417 165.0
CMS2_k127_7010624_15 PFAM D12 class N6 adenine-specific DNA methyltransferase K06223 - 2.1.1.72 0.000000000000000000000000009055 109.0
CMS2_k127_7010624_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.526e-222 694.0
CMS2_k127_7010624_3 Archaeal ammonia monooxygenase subunit A (AmoA) K10944 - 1.14.18.3,1.14.99.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 436.0
CMS2_k127_7010624_4 PFAM Ammonia monooxygenase methane monooxygenase, subunit C K10946 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 380.0
CMS2_k127_7010624_5 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 374.0
CMS2_k127_7010624_6 Monooxygenase subunit B protein K10945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004057 349.0
CMS2_k127_7010624_7 ATPase family associated with various cellular activities (AAA) K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 289.0
CMS2_k127_7010624_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003479 270.0
CMS2_k127_7010624_9 ribosomal protein K02956 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004064 269.0
CMS2_k127_7042189_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 7.428e-265 820.0
CMS2_k127_7042189_1 DinB superfamily - - - 8.227e-243 754.0
CMS2_k127_7042189_2 Radical SAM domain protein K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 550.0
CMS2_k127_7042189_3 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 496.0
CMS2_k127_7042189_4 - - - - 0.00000000000000000000000000000000000000004231 153.0
CMS2_k127_7042189_5 cheY-homologous receiver domain K03413 - - 0.0000000000000006226 83.0
CMS2_k127_7050581_0 Amino acid kinase family K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 432.0
CMS2_k127_7050581_1 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000637 425.0
CMS2_k127_7050581_2 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 357.0
CMS2_k127_7050581_3 NUDIX domain K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 338.0
CMS2_k127_7050581_4 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 334.0
CMS2_k127_73189_0 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 472.0
CMS2_k127_73189_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 396.0
CMS2_k127_73189_2 Winged helix-turn-helix - - - 0.00000000000000000000000000000000000000001073 155.0
CMS2_k127_73189_3 COG1522 Transcriptional regulators - - - 0.000000000000000000000000984 111.0
CMS2_k127_73189_4 - - - - 0.00000152 50.0
CMS2_k127_73189_5 - - - - 0.0001062 51.0
CMS2_k127_82211_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 367.0
CMS2_k127_82211_1 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000006848 244.0
CMS2_k127_82211_2 MafB19-like deaminase K01485 - 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000002654 225.0
CMS2_k127_82211_3 MgtC family K07507 - - 0.00000000000000000000000000000000000000001306 157.0
CMS2_k127_82211_4 glucosylceramidase activity - - - 0.00000000000000000000000000000668 121.0
CMS2_k127_88247_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 1.06e-249 775.0
CMS2_k127_88247_1 - - - - 0.00000000000007911 78.0
CMS2_k127_88247_2 - - - - 0.0000005419 54.0
CMS2_k127_937880_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.002e-290 897.0
CMS2_k127_937880_1 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 492.0
CMS2_k127_937880_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002773 276.0
CMS2_k127_979905_0 Peptidase family M1 domain K01256,K13722 - 3.4.11.2 0.0 1379.0
CMS2_k127_979905_1 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 9.835e-309 949.0
CMS2_k127_979905_2 LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 523.0
CMS2_k127_979905_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 376.0
CMS2_k127_979905_4 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002382 265.0