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Overview

ID MAG00433
Name CMS2_bin.45
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Dehalococcoidia
Order RBG-13-53-26
Family RBG-13-53-26
Genus RBG-13-53-26
Species
Assembly information
Completeness (%) 77.06
Contamination (%) 1.89
GC content (%) 61.0
N50 (bp) 3,938
Genome size (bp) 1,655,330

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1685

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1017981_0 DNA polymerase X family K02347 - - 2.04e-226 714.0
CMS2_k127_1017981_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 345.0
CMS2_k127_1017981_2 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000001422 222.0
CMS2_k127_1017981_3 Protein of unknown function (DUF2851) - - - 0.000000000000000000000000000000000000000003711 174.0
CMS2_k127_1017981_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000001265 156.0
CMS2_k127_1017981_5 helix-turn-helix domain protein - - - 0.0000000000000005323 81.0
CMS2_k127_1034955_0 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000157 278.0
CMS2_k127_1034955_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000002863 259.0
CMS2_k127_1036110_0 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 327.0
CMS2_k127_1036110_1 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002705 250.0
CMS2_k127_1036110_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000004669 257.0
CMS2_k127_1036110_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000007477 238.0
CMS2_k127_1036110_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000001606 212.0
CMS2_k127_1036110_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000008867 182.0
CMS2_k127_1036110_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000009589 90.0
CMS2_k127_1046872_0 PFAM Cytochrome C assembly protein K02198 - - 6.344e-203 650.0
CMS2_k127_1046872_1 Bacterial Ig-like domain 2 - - - 0.0000000000000000000000000000000000000000000005769 179.0
CMS2_k127_1046872_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000001446 113.0
CMS2_k127_1046872_4 Cytochrome c - - - 0.000000000000000008327 92.0
CMS2_k127_1057013_0 FAD dependent oxidoreductase K05898 - 1.3.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000001444 254.0
CMS2_k127_1057013_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000001491 190.0
CMS2_k127_1057013_2 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000004571 167.0
CMS2_k127_1057013_3 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000003528 165.0
CMS2_k127_1061775_0 Phosphofructokinase K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 451.0
CMS2_k127_1061775_1 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 384.0
CMS2_k127_1061775_2 DnaJ molecular chaperone homology domain K05516 - - 0.00000000000000000000000000000000000000000000002748 174.0
CMS2_k127_1077391_0 GXGXG motif - - - 0.0 1018.0
CMS2_k127_1077391_1 Glutamate synthase - - - 9.22e-211 675.0
CMS2_k127_1077391_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 356.0
CMS2_k127_1077391_3 glutamate synthase activity - - - 0.00000000000000000000000000000000000000000000003186 176.0
CMS2_k127_1077391_4 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000007838 165.0
CMS2_k127_1077391_5 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000006051 79.0
CMS2_k127_1104469_0 Phage capsid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 338.0
CMS2_k127_1104469_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 292.0
CMS2_k127_1104469_2 - - - - 0.00000000001029 73.0
CMS2_k127_1104469_3 - - - - 0.000000004258 59.0
CMS2_k127_1121535_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 593.0
CMS2_k127_1121535_1 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 575.0
CMS2_k127_1121535_2 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 451.0
CMS2_k127_1121535_3 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 297.0
CMS2_k127_1121535_4 Acyl-CoA dehydrogenase, middle domain K16173 - 1.3.99.32 0.000000005254 61.0
CMS2_k127_1122389_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 305.0
CMS2_k127_1122389_1 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002065 286.0
CMS2_k127_1122389_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002918 253.0
CMS2_k127_1148222_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008883 291.0
CMS2_k127_1164467_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 424.0
CMS2_k127_1164467_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 368.0
CMS2_k127_1164467_2 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000000000000000000000000000000000000000002071 213.0
CMS2_k127_1164467_3 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.0000000000001105 75.0
CMS2_k127_1164467_4 - - - - 0.00000000001618 68.0
CMS2_k127_1170064_0 transferase activity, transferring glycosyl groups K00754,K19422 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000001 195.0
CMS2_k127_1170064_1 dTDP biosynthetic process K00560,K00943 - 2.1.1.45,2.7.4.9 0.00000000009463 70.0
CMS2_k127_1170064_2 - - - - 0.0000007376 54.0
CMS2_k127_1185488_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005667 506.0
CMS2_k127_1219330_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 454.0
CMS2_k127_1219330_1 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000009161 195.0
CMS2_k127_1219330_2 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.0000000000000000000000000000002911 128.0
CMS2_k127_1223688_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 7.535e-206 653.0
CMS2_k127_1223688_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 333.0
CMS2_k127_1223688_2 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 316.0
CMS2_k127_1223688_3 Biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 309.0
CMS2_k127_1223688_4 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000002938 141.0
CMS2_k127_1223688_5 - - - - 0.000000001123 61.0
CMS2_k127_1223688_6 Predicted RNA-binding protein - - - 0.0000001994 54.0
CMS2_k127_123863_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007012 293.0
CMS2_k127_123863_1 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000647 264.0
CMS2_k127_123863_2 KR domain - - - 0.00000000000274 68.0
CMS2_k127_1239883_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 421.0
CMS2_k127_1239883_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003974 260.0
CMS2_k127_1239883_2 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000001339 220.0
CMS2_k127_1239883_3 Transcriptional regulator, Crp Fnr family K10914,K21563 - - 0.00000000000000000000000000000000000000000000000000000000002019 213.0
CMS2_k127_1239883_4 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000001336 209.0
CMS2_k127_1239883_5 CoA-binding domain protein K06929 - - 0.000000000000000000000000000000000000000004216 159.0
CMS2_k127_1239883_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000001023 102.0
CMS2_k127_1239883_7 NIL - - - 0.00000000000002406 76.0
CMS2_k127_1239883_8 Threonine synthase K01733 - 4.2.3.1 0.00000000001561 74.0
CMS2_k127_1239883_9 nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.00000009385 57.0
CMS2_k127_1240095_0 ATPase activity K02010,K02017,K02019,K02049,K02068,K02071,K06857,K10112 - 3.6.3.29,3.6.3.30,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 347.0
CMS2_k127_1240095_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001743 259.0
CMS2_k127_1240095_2 Flavodoxin - - - 0.0000000000000000000000000000000000000001593 156.0
CMS2_k127_1240095_3 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000008314 143.0
CMS2_k127_124132_0 Carboxylesterase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 385.0
CMS2_k127_124132_1 ATPase activity K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 332.0
CMS2_k127_124132_2 Secondary thiamine-phosphate synthase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000467 270.0
CMS2_k127_124132_3 PFAM Silent information regulator protein Sir2 K12410 - - 0.0000000000000000000000000000000000000000000000000000000000005831 220.0
CMS2_k127_124132_4 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000002232 183.0
CMS2_k127_124132_5 PFAM Transglutaminase-like - - - 0.000000000000000000000000000000000000132 148.0
CMS2_k127_124132_6 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000000001377 138.0
CMS2_k127_124132_7 amino acid activation for nonribosomal peptide biosynthetic process K17713 - - 0.000000000000000000000000000000419 135.0
CMS2_k127_124132_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000385 76.0
CMS2_k127_124132_9 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000008585 54.0
CMS2_k127_1294627_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 434.0
CMS2_k127_1294627_1 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002389 280.0
CMS2_k127_1294627_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000172 251.0
CMS2_k127_1294627_3 electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000409 186.0
CMS2_k127_1294627_4 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.0000000000000000000000000000000000002343 146.0
CMS2_k127_1307556_0 PFAM short-chain dehydrogenase reductase SDR K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000002617 217.0
CMS2_k127_1307556_1 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000343 201.0
CMS2_k127_1307556_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000004426 163.0
CMS2_k127_1307556_3 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.00000000000000000000000000000000000000001651 160.0
CMS2_k127_1320374_0 TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 432.0
CMS2_k127_1320374_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000002677 241.0
CMS2_k127_1334083_0 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 564.0
CMS2_k127_1334083_1 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 375.0
CMS2_k127_1334083_2 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000001178 231.0
CMS2_k127_1334083_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000002522 210.0
CMS2_k127_1373427_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000001346 105.0
CMS2_k127_137754_0 transposase activity - - - 0.00000000000000000000000000000000000000000000000000000000002957 214.0
CMS2_k127_137754_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000006028 180.0
CMS2_k127_137754_2 C-terminal domain of CHU protein family K20276 - - 0.0001015 53.0
CMS2_k127_1394091_0 PFAM Cys Met metabolism, pyridoxal phosphate-dependent enzyme K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 515.0
CMS2_k127_1394091_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 435.0
CMS2_k127_1394091_2 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 351.0
CMS2_k127_1446759_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 432.0
CMS2_k127_1446759_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 303.0
CMS2_k127_1446759_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000009509 93.0
CMS2_k127_1451184_0 RibD C-terminal domain K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000000000000007751 240.0
CMS2_k127_1451184_1 ATPase activity K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000009244 242.0
CMS2_k127_1451184_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000485 194.0
CMS2_k127_1459477_0 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 308.0
CMS2_k127_1459477_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 315.0
CMS2_k127_1459477_2 FAD binding domain K05898 - 1.3.99.4 0.0000000000000000000000000000001213 128.0
CMS2_k127_1467597_0 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 456.0
CMS2_k127_1467597_1 Formate dehydrogenase alpha subunit K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 364.0
CMS2_k127_1467597_2 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000002745 180.0
CMS2_k127_1472543_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 311.0
CMS2_k127_1472543_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000007509 220.0
CMS2_k127_1472543_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000004958 184.0
CMS2_k127_1477211_0 FAD dependent oxidoreductase K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 422.0
CMS2_k127_1477211_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 406.0
CMS2_k127_1477211_2 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 391.0
CMS2_k127_1477211_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000005273 241.0
CMS2_k127_1477211_4 Cl- channel, voltage-gated family protein K03281 - - 0.0000000000000000000000000000000000000000000000000000000000000000443 233.0
CMS2_k127_1477211_5 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.000000000000000000000002571 108.0
CMS2_k127_1477211_6 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 GO:0003674,GO:0003824,GO:0004553,GO:0004805,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009628,GO:0009651,GO:0009987,GO:0015927,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0019203,GO:0042578,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896 3.1.3.12 0.0000000000000000000008665 100.0
CMS2_k127_1477697_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 466.0
CMS2_k127_1477697_1 Isochorismatase family - - - 0.00000000000000000000000000004209 123.0
CMS2_k127_1477697_2 acetyl-CoA hydrolase - - - 0.0001024 46.0
CMS2_k127_1505531_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 356.0
CMS2_k127_1505531_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000134 190.0
CMS2_k127_1505531_2 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00001832 55.0
CMS2_k127_1505531_3 dUTP diphosphatase activity. It is involved in the biological process described with dUTP metabolic process K01520 GO:0000166,GO:0000287,GO:0001889,GO:0003674,GO:0003824,GO:0004170,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006259,GO:0006260,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010469,GO:0010646,GO:0010648,GO:0014070,GO:0015949,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019103,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0023051,GO:0023057,GO:0030545,GO:0030547,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032552,GO:0032556,GO:0034404,GO:0034641,GO:0034645,GO:0034654,GO:0034655,GO:0036094,GO:0042221,GO:0042975,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043393,GO:0043497,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048732,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051098,GO:0051259,GO:0051260,GO:0055086,GO:0061008,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0098772,GO:1901135,GO:1901136,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:2000272 3.6.1.23 0.00005738 49.0
CMS2_k127_1506309_0 PFAM Transketolase K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 368.0
CMS2_k127_1506309_1 Transketolase, central region K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 351.0
CMS2_k127_1506309_2 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000000000002794 155.0
CMS2_k127_1506309_3 membrane transporter protein K07090 - - 0.000945 43.0
CMS2_k127_1507_0 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 381.0
CMS2_k127_1507_1 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000003279 249.0
CMS2_k127_1507_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000225 207.0
CMS2_k127_1507_3 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000006552 128.0
CMS2_k127_1513822_0 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000003638 213.0
CMS2_k127_1513822_1 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000686 118.0
CMS2_k127_1513822_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000005537 103.0
CMS2_k127_153021_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 347.0
CMS2_k127_153021_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000263 198.0
CMS2_k127_1537750_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 4.175e-254 801.0
CMS2_k127_1537750_1 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 439.0
CMS2_k127_1537750_2 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002785 284.0
CMS2_k127_1537750_3 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006929 275.0
CMS2_k127_1537750_4 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002578 270.0
CMS2_k127_1537750_5 Dihydroxyacetone kinase family - - - 0.000000000000000000000000000000000000000000000000007249 193.0
CMS2_k127_1537750_6 ERG2 and Sigma1 receptor like protein K20719 - - 0.000000000000000000000000000000000000000000000004668 178.0
CMS2_k127_153811_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 349.0
CMS2_k127_153811_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000002511 208.0
CMS2_k127_1547715_0 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha- epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl- CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00192,K00193 - 1.2.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 302.0
CMS2_k127_1547715_1 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.000000000000000000000000000000000000000000000003622 189.0
CMS2_k127_1547715_2 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.0000000002389 66.0
CMS2_k127_1574925_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 464.0
CMS2_k127_1574925_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000004249 186.0
CMS2_k127_1574925_2 PKD domain - - - 0.000000002111 70.0
CMS2_k127_1575718_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 455.0
CMS2_k127_1575718_1 SCO1/SenC - - - 0.00000000000000000000000004343 108.0
CMS2_k127_1575718_2 alginic acid biosynthetic process - - - 0.00002852 48.0
CMS2_k127_159326_0 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 316.0
CMS2_k127_159326_1 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.000000000000000000000000000000000000000000000007533 177.0
CMS2_k127_159326_2 Pterin binding enzyme K00796 - 2.5.1.15 0.00000000000000000000000000000000000000001492 155.0
CMS2_k127_159326_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000005845 149.0
CMS2_k127_159326_4 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000001064 141.0
CMS2_k127_159326_5 Belongs to the UPF0434 family - - - 0.000000000000000000001602 95.0
CMS2_k127_164999_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 406.0
CMS2_k127_164999_2 ABC transporter K02003 - - 0.0000000000002116 70.0
CMS2_k127_1657759_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 583.0
CMS2_k127_1657759_1 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005289 250.0
CMS2_k127_1660452_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 551.0
CMS2_k127_1660452_1 lysyl-tRNA aminoacylation K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 557.0
CMS2_k127_1660452_2 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000004367 214.0
CMS2_k127_1660452_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000001352 203.0
CMS2_k127_1660452_4 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000002684 163.0
CMS2_k127_1660452_5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.00000000005126 66.0
CMS2_k127_1683587_0 IMP dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 354.0
CMS2_k127_1683587_1 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002694 286.0
CMS2_k127_1697713_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.851e-200 649.0
CMS2_k127_1697713_1 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 393.0
CMS2_k127_1697713_2 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002517 239.0
CMS2_k127_1702398_0 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 548.0
CMS2_k127_1702398_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 463.0
CMS2_k127_1702398_2 secreted hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001052 255.0
CMS2_k127_1702398_3 R3H domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009172 242.0
CMS2_k127_1702916_0 Periplasmic Protein - - - 0.000000000000000000000000000000000000000000000008072 185.0
CMS2_k127_1702916_1 - - - - 0.0000000000000000000000004823 114.0
CMS2_k127_1702916_2 - - - - 0.0000000000000000002513 98.0
CMS2_k127_1702916_3 Sigma-70 region 2 K03088 - - 0.0000000000000008517 81.0
CMS2_k127_1727920_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 337.0
CMS2_k127_1727920_1 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000762 334.0
CMS2_k127_1727920_2 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 316.0
CMS2_k127_1727920_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001288 272.0
CMS2_k127_1727920_4 4-phosphoerythronate dehydrogenase activity K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000003585 229.0
CMS2_k127_1727920_5 Domain of unknown function (DUF296) - - - 0.0000000000000000000000000000000000000000000000000000000001055 208.0
CMS2_k127_1727920_6 L-ribulose-5-phosphate 4-epimerase K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000458 199.0
CMS2_k127_1727920_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000001723 62.0
CMS2_k127_1737561_1 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000000000000163 240.0
CMS2_k127_1737561_2 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0000000001763 67.0
CMS2_k127_1737561_3 Belongs to the glycosyl hydrolase 18 family - - - 0.0004299 52.0
CMS2_k127_1752639_0 Pyridine nucleotide-disulphide oxidoreductase - - - 8.772e-223 704.0
CMS2_k127_1752639_1 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000284 238.0
CMS2_k127_1752639_2 KR domain - - - 0.0000000000000000000000000007319 123.0
CMS2_k127_1759068_0 PFAM Glycosyl hydrolase family 3 C terminal domain K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 444.0
CMS2_k127_1759068_1 Pkd domain containing protein - - - 0.0000000000000000000006281 102.0
CMS2_k127_177622_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03605 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 357.0
CMS2_k127_177622_1 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 301.0
CMS2_k127_177622_2 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.000000000000000000000000000000000000006371 154.0
CMS2_k127_177622_3 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000001049 150.0
CMS2_k127_177622_4 Dinitrogenase iron-molybdenum cofactor - - - 0.0000000000000000000000000000006947 125.0
CMS2_k127_177622_5 NAD(P)H-binding - - - 0.00000000000000000000000000007075 120.0
CMS2_k127_1782439_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.916e-239 753.0
CMS2_k127_1782439_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002035 263.0
CMS2_k127_1782439_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000002816 180.0
CMS2_k127_1782439_3 Reverse transcriptase-like K03469 - 3.1.26.4 0.000000000000000000000000000000000008808 142.0
CMS2_k127_1782439_4 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.0000000000000000000000000000008356 135.0
CMS2_k127_1782439_5 - - - - 0.00000003535 57.0
CMS2_k127_1782439_6 - - - - 0.0001477 46.0
CMS2_k127_1830787_0 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 587.0
CMS2_k127_1830787_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 441.0
CMS2_k127_1830787_2 Type II/IV secretion system protein K02652,K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 433.0
CMS2_k127_1830787_3 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000321 93.0
CMS2_k127_1830787_4 gas vesicle protein - - - 0.00000000003832 69.0
CMS2_k127_1838979_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 301.0
CMS2_k127_1841474_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 313.0
CMS2_k127_1841474_1 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000001277 198.0
CMS2_k127_1843148_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 464.0
CMS2_k127_1843148_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 337.0
CMS2_k127_1843148_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001983 286.0
CMS2_k127_1849083_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.185e-232 734.0
CMS2_k127_1849083_1 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000004994 92.0
CMS2_k127_1866732_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 469.0
CMS2_k127_1866732_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 442.0
CMS2_k127_1866732_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 307.0
CMS2_k127_1877099_0 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000000000000001021 167.0
CMS2_k127_1877099_1 Integrase core domain - - - 0.0000000000000000000000000000285 122.0
CMS2_k127_1938772_0 Methylene-tetrahydrofolate reductase C terminal K00297 - 1.5.1.20 3.012e-196 632.0
CMS2_k127_1938772_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 341.0
CMS2_k127_1938772_2 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000002331 262.0
CMS2_k127_1938772_3 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000000000131 155.0
CMS2_k127_1938772_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000002438 97.0
CMS2_k127_1943336_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001844 265.0
CMS2_k127_1943336_1 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000009923 223.0
CMS2_k127_1943336_2 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000069 224.0
CMS2_k127_1943336_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000003109 170.0
CMS2_k127_1943336_4 Domain of unknown function (DUF3786) - - - 0.0000792 51.0
CMS2_k127_1960874_0 ferredoxin iron-sulfur binding - - - 0.000000000000000000000000000000000000000000004875 176.0
CMS2_k127_1960874_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000003905 131.0
CMS2_k127_1965209_0 Ferrous iron transport protein B K04759 - - 2.783e-214 679.0
CMS2_k127_1965209_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 304.0
CMS2_k127_1965209_2 DNA-binding protein K06933 - - 0.000000000000000000000000000000000000001964 152.0
CMS2_k127_1965209_3 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.0000000000000000000000000006275 117.0
CMS2_k127_1965209_4 FeoA K04758 - - 0.00000000000000121 79.0
CMS2_k127_1971008_0 Integrase catalytic - - - 0.0000000000008517 79.0
CMS2_k127_1976500_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 1.046e-202 654.0
CMS2_k127_1976500_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 385.0
CMS2_k127_1976500_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 320.0
CMS2_k127_1976500_3 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 288.0
CMS2_k127_1976500_4 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000302 273.0
CMS2_k127_1976500_5 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000001294 158.0
CMS2_k127_1976500_6 Dodecin K09165 - - 0.000000000000000000000001506 105.0
CMS2_k127_1976500_7 - - - - 0.00000000000001747 74.0
CMS2_k127_1976500_8 Peptidase family M28 - - - 0.000000000001207 75.0
CMS2_k127_1976500_9 - - - - 0.000000003029 62.0
CMS2_k127_1982452_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 343.0
CMS2_k127_1982452_1 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 306.0
CMS2_k127_1982452_2 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000002354 231.0
CMS2_k127_1982452_3 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000002056 143.0
CMS2_k127_1982452_4 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000001177 119.0
CMS2_k127_1982452_5 peptidase U32 - - - 0.0000000000000000004237 91.0
CMS2_k127_2021283_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.033e-204 650.0
CMS2_k127_2021283_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0009163 43.0
CMS2_k127_2026655_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 576.0
CMS2_k127_2026655_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 433.0
CMS2_k127_2026655_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 398.0
CMS2_k127_2026655_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 295.0
CMS2_k127_2026655_4 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000003659 244.0
CMS2_k127_2026655_5 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000001402 81.0
CMS2_k127_2046763_0 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000006169 241.0
CMS2_k127_2046763_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000001914 112.0
CMS2_k127_2055417_0 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000001519 223.0
CMS2_k127_2055417_1 MgtC family K07507 - - 0.0000000000000000000000000000000001043 138.0
CMS2_k127_2055417_2 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000002084 132.0
CMS2_k127_2058671_0 Elongation factor G, domain IV K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 329.0
CMS2_k127_2058671_1 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000002087 259.0
CMS2_k127_2068160_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005588 585.0
CMS2_k127_2068160_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 310.0
CMS2_k127_2068160_2 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001275 285.0
CMS2_k127_2068160_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000001632 233.0
CMS2_k127_2068160_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000006124 209.0
CMS2_k127_2068160_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000004218 84.0
CMS2_k127_2068160_6 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000003458 67.0
CMS2_k127_2069109_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 317.0
CMS2_k127_2069109_1 Molybdenum cofactor synthesis domain - - - 0.00000000000000000000000000000000000000000000000000000000000003201 218.0
CMS2_k127_2069109_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000003071 151.0
CMS2_k127_2069109_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000376 123.0
CMS2_k127_2069109_4 FAD-dependent K07137 - - 0.00000000000000000000000000124 123.0
CMS2_k127_2076203_0 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001738 269.0
CMS2_k127_2076203_1 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000000000001666 187.0
CMS2_k127_2076203_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000003511 154.0
CMS2_k127_2076203_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000664 102.0
CMS2_k127_2076203_4 SNARE associated Golgi protein - - - 0.000000000000000001535 93.0
CMS2_k127_2082243_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000003138 237.0
CMS2_k127_2082243_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000001574 103.0
CMS2_k127_2093470_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 304.0
CMS2_k127_2093470_1 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004343 271.0
CMS2_k127_2110008_0 Pfam:Cache_2 K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003177 293.0
CMS2_k127_2111685_0 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 563.0
CMS2_k127_2111685_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 525.0
CMS2_k127_2111685_2 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 463.0
CMS2_k127_2111685_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000007016 232.0
CMS2_k127_2111685_4 - K07018 - - 0.00000000000000000000000000000000000000000000002358 178.0
CMS2_k127_2111685_5 LemA family K03744 - - 0.00000000000000000000000001624 109.0
CMS2_k127_2111685_6 Transglutaminase-like superfamily - - - 0.000000006526 65.0
CMS2_k127_211287_0 Binding-protein-dependent transport system inner membrane component K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 313.0
CMS2_k127_211287_1 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007462 283.0
CMS2_k127_2144827_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.611e-212 679.0
CMS2_k127_2144827_1 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001267 273.0
CMS2_k127_2144827_2 PAC2 family - - - 0.00000000000000000000000000000000000000004507 162.0
CMS2_k127_2144827_3 TM2 domain - - - 0.00000348 53.0
CMS2_k127_2151639_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 354.0
CMS2_k127_2151639_1 CheR methyltransferase, SAM binding domain protein K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000001056 228.0
CMS2_k127_2151639_2 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K03413 - - 0.0000000000000000000000000000000006907 132.0
CMS2_k127_2151639_3 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0004156 47.0
CMS2_k127_2153606_0 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 421.0
CMS2_k127_2153606_1 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005196 287.0
CMS2_k127_2153606_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004588 274.0
CMS2_k127_2153606_3 CoA-transferase activity K01039,K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000003768 255.0
CMS2_k127_2153606_4 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000009142 186.0
CMS2_k127_2153606_5 MaoC like domain - - - 0.0000000000000000000000000000000000000000001578 163.0
CMS2_k127_2153606_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000006111 145.0
CMS2_k127_2153606_7 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000762 140.0
CMS2_k127_216709_0 Conserved carboxylase domain K01960 - 6.4.1.1 1.881e-232 732.0
CMS2_k127_216709_1 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 552.0
CMS2_k127_216709_2 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 431.0
CMS2_k127_216709_3 TFIIE alpha subunit - - - 0.00000000000000000000000000000567 123.0
CMS2_k127_216709_4 Short C-terminal domain - - - 0.000000001067 66.0
CMS2_k127_2177783_0 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006981 278.0
CMS2_k127_2177783_1 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000002911 128.0
CMS2_k127_2177783_2 Nuclear transport factor 2 (NTF2) domain - - - 0.0000000000000000000000000000743 128.0
CMS2_k127_2190589_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 341.0
CMS2_k127_2190589_1 CoA-transferase family III K07543 - 2.8.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004898 278.0
CMS2_k127_2191264_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 533.0
CMS2_k127_2191264_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 441.0
CMS2_k127_2191264_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000006695 243.0
CMS2_k127_2191264_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000001039 124.0
CMS2_k127_2191264_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000001525 110.0
CMS2_k127_2193274_0 PFAM Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 285.0
CMS2_k127_2193274_1 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002157 247.0
CMS2_k127_2193274_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000009572 238.0
CMS2_k127_2195797_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 360.0
CMS2_k127_2195797_1 Peptidase dimerisation domain - - - 0.0000000000000001734 87.0
CMS2_k127_2195797_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000003746 66.0
CMS2_k127_2212571_0 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000228 134.0
CMS2_k127_2212571_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000004333 136.0
CMS2_k127_2229535_0 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 300.0
CMS2_k127_2229535_1 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000008381 216.0
CMS2_k127_2229535_2 Alpha/beta hydrolase family K06889,K07397 - - 0.00000000000000000000000000000000000001464 151.0
CMS2_k127_2257869_0 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000689 179.0
CMS2_k127_2257869_1 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000006802 156.0
CMS2_k127_2257869_2 leucyl-tRNA aminoacylation K01869 - 6.1.1.4 0.0000000000002975 75.0
CMS2_k127_2263158_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 302.0
CMS2_k127_2263158_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007391 271.0
CMS2_k127_2263158_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001354 272.0
CMS2_k127_2263158_3 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000004686 177.0
CMS2_k127_2263158_4 Abc transporter K01996 - - 0.000000000000000000000000001806 114.0
CMS2_k127_227741_0 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 385.0
CMS2_k127_227741_1 PFAM 2-nitropropane dioxygenase NPD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 307.0
CMS2_k127_227741_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000177 139.0
CMS2_k127_227741_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000009626 135.0
CMS2_k127_227741_4 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000004649 83.0
CMS2_k127_227741_5 nucleic-acid-binding protein containing a Zn-ribbon - - - 0.000000000000002217 83.0
CMS2_k127_2283222_0 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000005707 138.0
CMS2_k127_2283222_1 FAD dependent oxidoreductase - - - 0.000000000000003225 88.0
CMS2_k127_2283861_0 ferredoxin oxidoreductase beta subunit K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 417.0
CMS2_k127_2283861_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003719 254.0
CMS2_k127_2296384_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000153 262.0
CMS2_k127_2296384_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000002609 80.0
CMS2_k127_230245_0 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000006862 160.0
CMS2_k127_230245_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000116 160.0
CMS2_k127_230245_2 Thioesterase - - - 0.0004234 51.0
CMS2_k127_2309155_0 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 368.0
CMS2_k127_2309155_1 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 321.0
CMS2_k127_2309155_2 PFAM Glycoside hydrolase 15-related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 306.0
CMS2_k127_2309155_3 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007269 269.0
CMS2_k127_2309155_4 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000002264 189.0
CMS2_k127_2309155_5 Methionine biosynthesis protein MetW - - - 0.00000000003357 74.0
CMS2_k127_2309155_6 Methyltransferase domain - - - 0.0000000171 63.0
CMS2_k127_2332925_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 1.226e-224 721.0
CMS2_k127_2332925_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 478.0
CMS2_k127_2332925_10 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000476 63.0
CMS2_k127_2332925_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 447.0
CMS2_k127_2332925_3 CoA-transferase family III K07544 - 2.8.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003896 284.0
CMS2_k127_2332925_4 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001072 255.0
CMS2_k127_2332925_5 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000007298 186.0
CMS2_k127_2332925_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000008102 184.0
CMS2_k127_2332925_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000001325 159.0
CMS2_k127_2332925_8 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000001148 141.0
CMS2_k127_2332925_9 - - - - 0.00000000006279 69.0
CMS2_k127_2333645_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 578.0
CMS2_k127_2333645_1 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000009638 133.0
CMS2_k127_2337038_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 1.643e-212 676.0
CMS2_k127_2337038_1 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 301.0
CMS2_k127_2337038_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000003226 191.0
CMS2_k127_2340359_0 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 482.0
CMS2_k127_2340359_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000004295 203.0
CMS2_k127_2340359_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000001201 203.0
CMS2_k127_2340359_3 PFAM PHP domain K07053 - 3.1.3.97 0.0000004548 59.0
CMS2_k127_2347720_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 418.0
CMS2_k127_2347720_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 343.0
CMS2_k127_2347720_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 310.0
CMS2_k127_2347720_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000002206 241.0
CMS2_k127_2354331_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 611.0
CMS2_k127_2371207_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 454.0
CMS2_k127_2371207_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 346.0
CMS2_k127_2371207_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000007713 169.0
CMS2_k127_2371207_3 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000001964 89.0
CMS2_k127_23936_0 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 385.0
CMS2_k127_23936_1 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 344.0
CMS2_k127_23936_2 TIGRFAM MIP family channel K02440,K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 293.0
CMS2_k127_23936_3 Putative small multi-drug export protein - - - 0.000000000000000000000000000000000001886 143.0
CMS2_k127_23936_4 toxin-antitoxin pair type II binding - - - 0.000000000000000000000000003996 114.0
CMS2_k127_23936_5 Major Facilitator Superfamily K02575 - - 0.0000000004577 71.0
CMS2_k127_2397728_0 GH3 auxin-responsive promoter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003126 273.0
CMS2_k127_2397728_1 - - - - 0.0000000000000007482 83.0
CMS2_k127_2409302_0 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.000000000000000000000000003042 115.0
CMS2_k127_2409302_1 magnesium chelatase K03404,K03405 - 6.6.1.1 0.00000000002216 76.0
CMS2_k127_2423371_0 PFAM ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003559 269.0
CMS2_k127_2423371_1 ABC-type Mn2 Zn2 transport system, permease component K09816,K09819,K19976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001543 260.0
CMS2_k127_2423371_2 Belongs to the bacterial solute-binding protein 9 family K09815,K09818 - - 0.0000000000000000000000000000000157 129.0
CMS2_k127_2426386_0 electron transfer activity K00335,K02572,K03616 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 338.0
CMS2_k127_2426386_1 choline dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 304.0
CMS2_k127_2426982_0 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 496.0
CMS2_k127_2426982_1 AsnC family - - - 0.000000000000000000000000000000000000000000005017 169.0
CMS2_k127_2426982_2 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000001574 156.0
CMS2_k127_2426982_3 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000145 120.0
CMS2_k127_2426982_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000376 64.0
CMS2_k127_2426982_5 Winged helix DNA-binding domain - - - 0.00000008158 60.0
CMS2_k127_2431203_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 383.0
CMS2_k127_2431203_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 364.0
CMS2_k127_2431203_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001006 254.0
CMS2_k127_2431203_3 MOSC domain - - - 0.000000000000000000000000000000000000000000000000005503 184.0
CMS2_k127_2431203_4 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000915 182.0
CMS2_k127_2432480_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 3.94e-219 704.0
CMS2_k127_2432480_1 4Fe-4S dicluster domain K00124,K07307 - - 0.000000000000000000000000000000000000000000000000000000000000000001504 231.0
CMS2_k127_2432480_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306 - 1.8.5.3 0.00000000000000000000001288 106.0
CMS2_k127_2432480_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000002648 106.0
CMS2_k127_2432480_4 Lactoylglutathione lyase - - - 0.000000000000000000003945 99.0
CMS2_k127_2438269_0 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.0000000000000000000000000000000000000000000000000000009822 197.0
CMS2_k127_2438269_1 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.0000000000000000000000000001005 120.0
CMS2_k127_2438269_2 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000005849 93.0
CMS2_k127_2438908_0 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 346.0
CMS2_k127_2438908_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003235 258.0
CMS2_k127_2438908_2 Protein of unknown function (DUF448) K07742 - - 0.000000000000004019 79.0
CMS2_k127_244715_0 dipeptide transport K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 567.0
CMS2_k127_244715_1 PFAM PfkB K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 374.0
CMS2_k127_244715_2 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 370.0
CMS2_k127_244715_3 nitrogen compound transport K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 352.0
CMS2_k127_244715_4 COG0444 ABC-type dipeptide oligopeptide nickel transport system ATPase component K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 309.0
CMS2_k127_244715_5 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004485 287.0
CMS2_k127_2475129_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase K02182 - 6.2.1.48 3.845e-245 766.0
CMS2_k127_2475129_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000433 211.0
CMS2_k127_2475129_2 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000002708 87.0
CMS2_k127_2517202_0 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 325.0
CMS2_k127_2517202_1 protein histidine kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001109 243.0
CMS2_k127_2521467_0 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001919 257.0
CMS2_k127_2521467_1 Protein of unknown function (DUF933) K06942 - - 0.00000000000000000000000000000000000000000000003018 173.0
CMS2_k127_2521467_2 Belongs to the phosphoglycerate mutase family K22305 - 3.1.3.3 0.00000000000000000000000000000000000000005546 159.0
CMS2_k127_2525793_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000004277 218.0
CMS2_k127_2525793_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000001439 162.0
CMS2_k127_2525793_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000176 103.0
CMS2_k127_255316_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007948 365.0
CMS2_k127_255316_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 354.0
CMS2_k127_255316_10 PFAM nitrogen-fixing NifU domain protein - - - 0.0004845 45.0
CMS2_k127_255316_2 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 326.0
CMS2_k127_255316_3 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 318.0
CMS2_k127_255316_4 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000002639 269.0
CMS2_k127_255316_5 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000001417 224.0
CMS2_k127_255316_6 TIGRFAM degV family protein - - - 0.00000000000000000000000000000000000000000000000006133 188.0
CMS2_k127_255316_7 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000001737 166.0
CMS2_k127_255316_8 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000001871 157.0
CMS2_k127_255316_9 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000001239 106.0
CMS2_k127_2581362_0 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001697 225.0
CMS2_k127_2588246_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009607 302.0
CMS2_k127_2588246_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000002506 208.0
CMS2_k127_2593691_0 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003493 267.0
CMS2_k127_2593691_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000001405 237.0
CMS2_k127_2593691_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000001323 224.0
CMS2_k127_2593691_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000007361 197.0
CMS2_k127_2593691_4 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000004037 144.0
CMS2_k127_2598275_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 464.0
CMS2_k127_2598275_1 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000001961 207.0
CMS2_k127_2602757_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 473.0
CMS2_k127_2602757_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000001659 260.0
CMS2_k127_2602757_2 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000186 134.0
CMS2_k127_2609688_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.563e-197 632.0
CMS2_k127_2609688_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 596.0
CMS2_k127_2609688_2 Cysteine-rich domain K00113 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004466 295.0
CMS2_k127_2609688_3 Beta-lactamase superfamily domain - - - 0.00000000000000000001637 102.0
CMS2_k127_2609688_4 SMART protein phosphatase 2C domain protein - - - 0.0008582 48.0
CMS2_k127_2612572_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 355.0
CMS2_k127_2612572_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000002198 215.0
CMS2_k127_2612572_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000005283 202.0
CMS2_k127_2612572_3 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000003456 118.0
CMS2_k127_2612572_4 - - - - 0.0000000000001102 75.0
CMS2_k127_2647322_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 292.0
CMS2_k127_2647322_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000001052 193.0
CMS2_k127_2651667_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 493.0
CMS2_k127_2651667_1 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000003175 177.0
CMS2_k127_2651667_2 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000002406 76.0
CMS2_k127_2662857_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 9.206e-215 681.0
CMS2_k127_2664412_0 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 574.0
CMS2_k127_2664412_1 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 358.0
CMS2_k127_2664412_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000127 222.0
CMS2_k127_2664412_3 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 0.0000000000000000000000000000000000001048 144.0
CMS2_k127_2668217_0 Heavy metal transport detoxification protein K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 557.0
CMS2_k127_2677205_0 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 291.0
CMS2_k127_2677205_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007198 284.0
CMS2_k127_2677205_2 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000003678 136.0
CMS2_k127_2677205_3 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000007151 136.0
CMS2_k127_2677205_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000005302 106.0
CMS2_k127_2677205_5 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000003864 98.0
CMS2_k127_2677205_6 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000002135 74.0
CMS2_k127_2681182_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.05e-198 628.0
CMS2_k127_2681182_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 345.0
CMS2_k127_2681182_2 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 304.0
CMS2_k127_2681182_3 PFAM PP-loop domain protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 292.0
CMS2_k127_2681182_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006078 274.0
CMS2_k127_2682194_0 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000005483 203.0
CMS2_k127_2709308_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 332.0
CMS2_k127_2709308_1 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009762 271.0
CMS2_k127_2709308_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000001682 213.0
CMS2_k127_2709308_3 TIGRFAM Potassium uptake protein TrkH K03498 - - 0.00000000000000000000000000000000000000000000000000000001729 208.0
CMS2_k127_2709308_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000005575 161.0
CMS2_k127_272656_0 PFAM Beta propeller domain K14475 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 321.0
CMS2_k127_272656_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 292.0
CMS2_k127_272656_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000005859 231.0
CMS2_k127_272656_3 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000001737 213.0
CMS2_k127_2749954_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 383.0
CMS2_k127_2749954_1 DUF35 OB-fold domain, acyl-CoA-associated K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 325.0
CMS2_k127_2749954_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000005881 148.0
CMS2_k127_2750437_0 4 iron, 4 sulfur cluster binding K02574 - - 0.00000000000000000000000000000000000000000000002792 179.0
CMS2_k127_2750437_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000001279 171.0
CMS2_k127_2750437_2 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000003096 132.0
CMS2_k127_2750437_3 Thiamine-binding protein - - - 0.00000000000000000000000005608 110.0
CMS2_k127_2750437_4 Thioredoxin - - - 0.000000000000000006865 89.0
CMS2_k127_2750437_5 Belongs to the Fur family K09823 - - 0.00000000000000003969 86.0
CMS2_k127_2750437_6 COG NOG16874 non supervised orthologous group - - - 0.00001672 54.0
CMS2_k127_2765606_0 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000007976 232.0
CMS2_k127_2765606_1 cellulase activity - - - 0.000000000000000000000000000000000000000001127 171.0
CMS2_k127_2772811_0 B12 binding domain - - - 5.097e-200 637.0
CMS2_k127_2772811_1 Arsenical pump membrane protein K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008907 544.0
CMS2_k127_278364_0 Short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000009445 260.0
CMS2_k127_278364_1 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001739 257.0
CMS2_k127_278364_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002641 249.0
CMS2_k127_278364_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000691 236.0
CMS2_k127_278364_4 - - - - 0.00000000498 65.0
CMS2_k127_2786060_0 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 524.0
CMS2_k127_2786060_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 422.0
CMS2_k127_2786060_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001514 272.0
CMS2_k127_2786060_3 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0000000000000000000000000000000000000000000000000000002963 196.0
CMS2_k127_2786060_4 acetyltransferase K18815 - 2.3.1.82 0.0000000000000000000000000000000007888 138.0
CMS2_k127_2786060_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000009668 119.0
CMS2_k127_2786986_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000977 319.0
CMS2_k127_2786986_1 tRNA nucleotidyltransferase domain 2 putative K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000492 263.0
CMS2_k127_2786986_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000005436 227.0
CMS2_k127_2786986_3 domain protein K06951 - - 0.000000000000135 72.0
CMS2_k127_2823847_0 Transposase (IS116 IS110 IS902 family) - - - 0.0000000000000000000000000000000000000000000000000000000000001294 225.0
CMS2_k127_283315_0 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000009154 226.0
CMS2_k127_283315_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000002567 217.0
CMS2_k127_283315_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000001374 195.0
CMS2_k127_283315_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000001672 168.0
CMS2_k127_283315_4 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000001106 151.0
CMS2_k127_283315_5 - - - - 0.0001603 46.0
CMS2_k127_2841448_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 309.0
CMS2_k127_2841448_2 ig-like, plexins, transcription factors - - - 0.000000000000000000000000000000000000000000000009225 193.0
CMS2_k127_2841448_3 EthD domain - - - 0.000000000000000008646 87.0
CMS2_k127_2843963_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 520.0
CMS2_k127_2843963_1 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000007627 123.0
CMS2_k127_2854539_0 Hydantoinase/oxoprolinase N-terminal region - - - 2.223e-221 707.0
CMS2_k127_2854539_1 Acetone carboxylase gamma K10856 - 6.4.1.6 0.0000000000000000000000000000000000000000000000000000000000000002816 223.0
CMS2_k127_2854539_2 Dehydrogenase - - - 0.00000000000000000005459 95.0
CMS2_k127_287658_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000001089 243.0
CMS2_k127_287658_1 ig-like, plexins, transcription factors - - - 0.0000000000000000000000000000008676 141.0
CMS2_k127_287658_2 FMN binding - - - 0.00000000000000000000000002309 118.0
CMS2_k127_287658_3 protein acetylation K02348 - - 0.00000000000000000000000007714 111.0
CMS2_k127_2883268_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 359.0
CMS2_k127_2883268_1 nitrite reductase [NAD(P)H] activity K00363,K05710 - 1.7.1.15 0.000000000000000000001263 98.0
CMS2_k127_2887021_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 370.0
CMS2_k127_2887021_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000001893 184.0
CMS2_k127_2887021_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000002012 138.0
CMS2_k127_2887021_3 - - - - 0.0000000000000001978 81.0
CMS2_k127_2897932_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005276 548.0
CMS2_k127_2897932_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 446.0
CMS2_k127_2903573_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 555.0
CMS2_k127_2903573_1 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 320.0
CMS2_k127_2903573_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000002439 154.0
CMS2_k127_2914979_0 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.0000000000000000000000000000000000000000000002065 182.0
CMS2_k127_2914979_1 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.00000000000000000000000000005026 124.0
CMS2_k127_2914979_2 formylmethanofuran dehydrogenase, subunit G K11260 - - 0.000000000000000000000004078 108.0
CMS2_k127_2914979_3 PFAM molydopterin dinucleotide-binding region K00203 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 1.2.7.12 0.00000004351 60.0
CMS2_k127_2919063_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 434.0
CMS2_k127_2919063_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000239 174.0
CMS2_k127_2919063_2 Belongs to the enoyl-CoA hydratase isomerase family K07546 - - 0.000000000000000000000000000000000003854 142.0
CMS2_k127_2922615_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005291 260.0
CMS2_k127_2922615_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000005717 188.0
CMS2_k127_2948790_0 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000003074 164.0
CMS2_k127_2948790_1 Conserved carboxylase domain K01960 - 6.4.1.1 0.0000000000000000000000000000007055 121.0
CMS2_k127_2948790_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000028 63.0
CMS2_k127_2976098_0 GMC oxidoreductase - - - 3.278e-210 671.0
CMS2_k127_2976098_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 451.0
CMS2_k127_2976098_2 Protein of unknown function (DUF1385) K09153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 297.0
CMS2_k127_2976098_3 EthD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001201 260.0
CMS2_k127_2976098_4 Ribosomal L27 protein K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000025 136.0
CMS2_k127_2976098_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000002429 126.0
CMS2_k127_2976098_6 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000245 112.0
CMS2_k127_2976098_7 - - - - 0.000001232 58.0
CMS2_k127_3006959_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 398.0
CMS2_k127_3006959_1 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 299.0
CMS2_k127_3006959_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000171 121.0
CMS2_k127_3010165_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 500.0
CMS2_k127_3010165_1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002602 237.0
CMS2_k127_3010165_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000003233 201.0
CMS2_k127_3010165_3 reductase, subunit A K16950 - - 0.00000000000000007812 84.0
CMS2_k127_3017308_0 magnesium chelatase K03405 - 6.6.1.1 0.00000000000000000000000000000000004312 151.0
CMS2_k127_3017308_1 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.00000000000000000000000000001864 121.0
CMS2_k127_303043_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000586 274.0
CMS2_k127_303043_1 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001645 271.0
CMS2_k127_303043_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000001106 264.0
CMS2_k127_303043_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000005379 206.0
CMS2_k127_303043_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000102 143.0
CMS2_k127_303043_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000002173 66.0
CMS2_k127_303780_0 VWA containing CoxE family protein K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 440.0
CMS2_k127_303780_1 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 391.0
CMS2_k127_303780_10 N-terminal half of MaoC dehydratase - - - 0.00001882 57.0
CMS2_k127_303780_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000007002 245.0
CMS2_k127_303780_3 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003155 242.0
CMS2_k127_303780_4 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000006823 239.0
CMS2_k127_303780_5 FMN-dependent dehydrogenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000002303 198.0
CMS2_k127_303780_6 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000008565 177.0
CMS2_k127_303780_7 MaoC like domain - - - 0.0000000000000000000000000000000000938 138.0
CMS2_k127_303780_8 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.00000000000000000000000000001861 123.0
CMS2_k127_303780_9 FtsZ-dependent cytokinesis - - - 0.0000000000000000000006605 104.0
CMS2_k127_3043475_0 Elongation factor G C-terminus K06207 - - 4.323e-239 749.0
CMS2_k127_3045036_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.271e-223 704.0
CMS2_k127_3045036_1 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000003372 190.0
CMS2_k127_3045036_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000000000000000000000000000000003027 167.0
CMS2_k127_3045036_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000001766 91.0
CMS2_k127_3076152_0 BadF BadG BcrA BcrD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 356.0
CMS2_k127_3076152_1 Enoyl-CoA hydratase/isomerase K07546 - - 0.0000000000000000000000000002478 117.0
CMS2_k127_3093355_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 511.0
CMS2_k127_3093355_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 465.0
CMS2_k127_3093355_2 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 291.0
CMS2_k127_3093355_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000001643 213.0
CMS2_k127_3093355_4 SMART HNH nuclease - - - 0.000000000000000000000000000000000000000000000000002297 188.0
CMS2_k127_3093355_5 Chromatin associated protein KTI12 - - - 0.0000000000000000000000000000000003262 139.0
CMS2_k127_3127941_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003993 250.0
CMS2_k127_3134813_0 Belongs to the SEDS family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 579.0
CMS2_k127_3134813_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000005864 70.0
CMS2_k127_3135913_0 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000001332 201.0
CMS2_k127_3135913_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K16264 - - 0.00000000000000000000000007061 115.0
CMS2_k127_3135913_2 Transglutaminase-like - - - 0.0000000000001773 74.0
CMS2_k127_3160736_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 9.517e-260 829.0
CMS2_k127_3160736_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 469.0
CMS2_k127_3160736_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 389.0
CMS2_k127_3160736_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000178 279.0
CMS2_k127_3160736_4 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004891 269.0
CMS2_k127_3160736_5 Carbon-nitrogen hydrolase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001713 246.0
CMS2_k127_3160736_6 Fibronectin type 3 domain - - - 0.0000156 51.0
CMS2_k127_3168879_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008235 317.0
CMS2_k127_3168879_1 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 313.0
CMS2_k127_3168879_2 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 297.0
CMS2_k127_3168879_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000001226 67.0
CMS2_k127_318111_0 FMN-dependent dehydrogenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000001473 252.0
CMS2_k127_318111_1 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000009811 201.0
CMS2_k127_318111_2 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000002549 94.0
CMS2_k127_318111_3 NAD(P)H dehydrogenase (quinone) activity - - - 0.0000000000001817 79.0
CMS2_k127_3188761_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 591.0
CMS2_k127_3188761_1 DUF35 OB-fold domain, acyl-CoA-associated K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005657 433.0
CMS2_k127_3192289_0 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004116 256.0
CMS2_k127_3192289_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000002051 151.0
CMS2_k127_3196844_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000002056 271.0
CMS2_k127_3196844_1 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000000000000000000000000000000000000000000000000000212 227.0
CMS2_k127_3196844_2 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000008404 181.0
CMS2_k127_3196844_3 - - - - 0.000000000000000000008836 93.0
CMS2_k127_3200355_0 Domain of unknown function (DUF1731) K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004169 253.0
CMS2_k127_3200355_1 Uncharacterized conserved protein (COG2071) - - - 0.00000000000000000000002615 108.0
CMS2_k127_3203365_0 PFAM short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000006416 241.0
CMS2_k127_3203365_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000001244 235.0
CMS2_k127_3209580_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 532.0
CMS2_k127_3209580_1 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 387.0
CMS2_k127_3209580_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 317.0
CMS2_k127_3209580_3 Belongs to the enoyl-CoA hydratase isomerase family K07546,K08299,K15866 - 4.2.1.149,5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000001055 231.0
CMS2_k127_3209580_4 Phage integrase, N-terminal SAM-like domain K04763 - - 0.00000000000000000000000000000000000000000000000000000000007275 213.0
CMS2_k127_3209580_5 HIT domain K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000002051 205.0
CMS2_k127_3209580_6 Caspase domain - - - 0.000000009096 65.0
CMS2_k127_3214615_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003191 289.0
CMS2_k127_3214615_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003216 264.0
CMS2_k127_3231405_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 327.0
CMS2_k127_3231405_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000001246 121.0
CMS2_k127_3231405_2 NAD(P)-binding Rossmann-like domain - - - 0.000000000002317 70.0
CMS2_k127_3248975_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007843 575.0
CMS2_k127_3248975_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000003146 187.0
CMS2_k127_3261525_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 601.0
CMS2_k127_3261525_1 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 373.0
CMS2_k127_3261525_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000001186 121.0
CMS2_k127_3261525_3 PFAM zinc finger, SWIM domain protein - - - 0.0000000000000000000000000006029 115.0
CMS2_k127_326659_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007932 471.0
CMS2_k127_326659_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 379.0
CMS2_k127_326659_2 PFAM Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000001543 129.0
CMS2_k127_3278199_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 3.96e-265 827.0
CMS2_k127_3278199_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 466.0
CMS2_k127_3278199_2 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002265 264.0
CMS2_k127_3279798_0 Fe-S oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 586.0
CMS2_k127_3279798_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 419.0
CMS2_k127_3279798_2 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 288.0
CMS2_k127_3279798_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002489 298.0
CMS2_k127_3279798_4 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000001601 233.0
CMS2_k127_3279798_5 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000003139 224.0
CMS2_k127_3279798_6 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00125 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000002048 211.0
CMS2_k127_3279798_7 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000001938 164.0
CMS2_k127_3279798_8 4Fe-4S dicluster domain - - - 0.000000000000000000000005441 115.0
CMS2_k127_3281641_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 352.0
CMS2_k127_3281641_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000002705 250.0
CMS2_k127_3281641_2 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000001412 61.0
CMS2_k127_3296293_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009129 563.0
CMS2_k127_3296293_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 422.0
CMS2_k127_3296293_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 294.0
CMS2_k127_3306923_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 2.056e-201 647.0
CMS2_k127_3306923_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 544.0
CMS2_k127_3306923_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 523.0
CMS2_k127_3306923_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 417.0
CMS2_k127_3306923_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000001961 207.0
CMS2_k127_3306923_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000347 149.0
CMS2_k127_3306923_6 4Fe-4S dicluster domain K05580 - 1.6.5.3 0.00000000000000000000000000000000008243 139.0
CMS2_k127_3306923_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K05576 - 1.6.5.3 0.00000000000000000000000000001026 128.0
CMS2_k127_33602_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 2.123e-222 699.0
CMS2_k127_33602_1 Molybdopterin oxidoreductase, Fe4S4 K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002275 275.0
CMS2_k127_3371307_0 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 464.0
CMS2_k127_3371307_1 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 441.0
CMS2_k127_3371307_2 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 382.0
CMS2_k127_3371307_3 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 323.0
CMS2_k127_3371307_4 leucine import across plasma membrane K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006846 299.0
CMS2_k127_3371307_5 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.000000000000000000000000000000000007079 137.0
CMS2_k127_3371751_0 PFAM Alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 468.0
CMS2_k127_3371751_1 Acetolactate synthase, large subunit K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001071 264.0
CMS2_k127_3371751_2 PFAM GAF domain protein - - - 0.0000000000000000000000000000000000000000606 160.0
CMS2_k127_3371751_3 PFAM Antibiotic biosynthesis monooxygenase - - - 0.000000000000000002889 92.0
CMS2_k127_3371751_4 PFAM Antibiotic biosynthesis monooxygenase - - - 0.000000000000001184 81.0
CMS2_k127_3371751_5 SMART phosphoesterase PHP domain protein - - - 0.000004376 55.0
CMS2_k127_3403731_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.292e-204 653.0
CMS2_k127_3403731_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 584.0
CMS2_k127_3403731_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000312 231.0
CMS2_k127_3403731_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000001366 186.0
CMS2_k127_3403731_4 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.00000000000000000000000000000000000000000000003423 174.0
CMS2_k127_3403731_5 ACT domain - - - 0.00000000000000000000000000000000000000000166 159.0
CMS2_k127_3407022_0 - - - - 0.0000000000000000000000003552 113.0
CMS2_k127_3407022_1 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000002517 99.0
CMS2_k127_3416955_0 HEAT repeat - - - 0.000000000000000000000000000000002802 143.0
CMS2_k127_3416955_1 Protein conserved in bacteria - - - 0.000001676 54.0
CMS2_k127_3422878_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 529.0
CMS2_k127_3422878_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 497.0
CMS2_k127_3422878_10 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000000005921 179.0
CMS2_k127_3422878_11 - - - - 0.00000000000000000000000000000000000000001514 159.0
CMS2_k127_3422878_12 - - - - 0.000000000000000000000000000003005 120.0
CMS2_k127_3422878_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000003722 116.0
CMS2_k127_3422878_14 dUTPase K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006163,GO:0006195,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035862,GO:0035863,GO:0035870,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000008394 104.0
CMS2_k127_3422878_15 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000003553 81.0
CMS2_k127_3422878_16 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000004265 61.0
CMS2_k127_3422878_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 481.0
CMS2_k127_3422878_3 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 442.0
CMS2_k127_3422878_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 446.0
CMS2_k127_3422878_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 412.0
CMS2_k127_3422878_6 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 327.0
CMS2_k127_3422878_7 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 296.0
CMS2_k127_3422878_8 GTP cyclohydrolase I activity K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000003281 260.0
CMS2_k127_3422878_9 competence protein - - - 0.00000000000000000000000000000000000000000000000000000001128 205.0
CMS2_k127_3426833_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007665 288.0
CMS2_k127_3426833_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000194 163.0
CMS2_k127_3427768_0 Phage capsid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 333.0
CMS2_k127_3427768_1 Phage portal protein, SPP1 Gp6-like - - - 0.000000000000000000000000000000000000000000000000003073 189.0
CMS2_k127_3450692_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008906 239.0
CMS2_k127_3466128_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004123 241.0
CMS2_k127_3466280_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 394.0
CMS2_k127_3466280_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000392 225.0
CMS2_k127_3466280_2 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000004382 202.0
CMS2_k127_3474176_1 short-chain dehydrogenase K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 360.0
CMS2_k127_3499023_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1160.0
CMS2_k127_3499023_1 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 422.0
CMS2_k127_3499023_2 Domain of unknown function (DUF2437) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001455 285.0
CMS2_k127_3499023_3 Glutaredoxin K03676,K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000003374 165.0
CMS2_k127_3499023_4 Heat shock protein DnaJ domain protein K05516 - - 0.0005401 43.0
CMS2_k127_3499251_0 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.000002243 56.0
CMS2_k127_3531350_0 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000003147 218.0
CMS2_k127_3539206_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 1.038e-238 754.0
CMS2_k127_3539206_1 Telomere recombination K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 590.0
CMS2_k127_3539206_2 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000008209 180.0
CMS2_k127_3546902_0 antibiotic catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 361.0
CMS2_k127_3546902_1 Acetyl-CoA hydrolase/transferase C-terminal domain K18122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 318.0
CMS2_k127_3546902_2 RNA recognition motif - - - 0.000000000000000000000000000002587 123.0
CMS2_k127_3546902_3 Probable zinc-ribbon domain - - - 0.0000000000000001481 79.0
CMS2_k127_3560707_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 374.0
CMS2_k127_3560707_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000005676 262.0
CMS2_k127_3560707_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000003181 67.0
CMS2_k127_3575993_0 metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 334.0
CMS2_k127_3575993_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001982 227.0
CMS2_k127_3582318_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 379.0
CMS2_k127_3582318_2 domain protein - - - 0.00000000009264 71.0
CMS2_k127_3582318_3 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000005482 62.0
CMS2_k127_3606564_0 formate C-acetyltransferase K20038 - 4.3.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001078 267.0
CMS2_k127_3606564_1 glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.0000000000000000000000000000003826 124.0
CMS2_k127_3614412_0 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 439.0
CMS2_k127_3614412_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 373.0
CMS2_k127_3652308_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 373.0
CMS2_k127_3652308_1 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007054 316.0
CMS2_k127_3652308_2 heat shock protein binding - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000004903 87.0
CMS2_k127_3652308_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0005282 50.0
CMS2_k127_3692154_0 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 407.0
CMS2_k127_3692154_1 Belongs to the carbamoyltransferase HypF family K04656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 304.0
CMS2_k127_3692154_2 HupF/HypC family K04653 - - 0.000000000000000002415 86.0
CMS2_k127_3720271_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 578.0
CMS2_k127_3720271_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003853 267.0
CMS2_k127_3720271_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000002093 228.0
CMS2_k127_3720271_3 cysteinyl-tRNA aminoacylation K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000003281 187.0
CMS2_k127_3720271_4 Preprotein translocase SecG subunit K03075 - - 0.000000000000000009299 84.0
CMS2_k127_3720271_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000009817 54.0
CMS2_k127_3765922_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003111 417.0
CMS2_k127_3766893_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000001714 97.0
CMS2_k127_3766893_1 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000003553 104.0
CMS2_k127_3766893_2 peptidase activity, acting on L-amino acid peptides K20276,K21449 - - 0.0000001876 62.0
CMS2_k127_3766893_3 Belongs to the peptidase S8 family - - - 0.00001187 53.0
CMS2_k127_3790742_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 295.0
CMS2_k127_3790742_1 PFAM thioesterase superfamily - - - 0.00000000000000000006446 95.0
CMS2_k127_3790742_2 CoA-binding domain protein - - - 0.0000000000000267 77.0
CMS2_k127_3799957_0 Nickel-dependent hydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 330.0
CMS2_k127_3799957_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 309.0
CMS2_k127_3799957_2 coenzyme F420 hydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 294.0
CMS2_k127_3862772_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 388.0
CMS2_k127_3862772_1 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 353.0
CMS2_k127_3866369_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 395.0
CMS2_k127_3866369_1 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000003949 176.0
CMS2_k127_387141_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 366.0
CMS2_k127_387141_1 Glucose-6-phosphate isomerase (GPI) K06859 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000001083 205.0
CMS2_k127_387141_2 KDPG and KHG aldolase - - - 0.00000000000000000000000000000000000000000000004137 173.0
CMS2_k127_3878364_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 1.823e-211 676.0
CMS2_k127_3878364_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 328.0
CMS2_k127_3878364_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00076 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008709,GO:0009056,GO:0009987,GO:0016043,GO:0016054,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0030573,GO:0032787,GO:0033764,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901360,GO:1901575,GO:1901615 1.1.1.159 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 287.0
CMS2_k127_3878364_3 DnaJ molecular chaperone homology domain K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001962 253.0
CMS2_k127_3878364_4 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000009093 235.0
CMS2_k127_3878364_5 - - - - 0.00003034 49.0
CMS2_k127_3907137_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 318.0
CMS2_k127_3907137_1 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005249 284.0
CMS2_k127_3907137_2 CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003021 268.0
CMS2_k127_3907137_3 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001054 267.0
CMS2_k127_3907137_4 Anion-transporting ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002771 243.0
CMS2_k127_3907137_5 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB - - - 0.0000000000000000000000000000000000000000000000000000000000000000001663 243.0
CMS2_k127_3907137_6 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000412 153.0
CMS2_k127_3907137_7 Hydantoin racemase K16841 - 5.1.99.3 0.0000000000000000006313 96.0
CMS2_k127_3907137_8 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.0000000001132 72.0
CMS2_k127_3960526_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000009699 251.0
CMS2_k127_3960526_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000834 161.0
CMS2_k127_3960526_2 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.000000000000000000000000000000000005158 141.0
CMS2_k127_3960526_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000002379 130.0
CMS2_k127_3960526_4 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000001376 121.0
CMS2_k127_3967985_0 ABC-type sugar transport system periplasmic component K10232 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 546.0
CMS2_k127_3967985_1 carbohydrate transport K02027 - - 0.0000000000000000000000000000000001714 151.0
CMS2_k127_4018998_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 1.164e-203 653.0
CMS2_k127_4018998_1 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000192 220.0
CMS2_k127_4018998_2 cellulase activity - - - 0.00000000000000000000000000000000000000000000002836 187.0
CMS2_k127_4018998_3 KR domain K00059 - 1.1.1.100 0.00001041 48.0
CMS2_k127_4018998_4 Calcineurin-like phosphoesterase - - - 0.000837 51.0
CMS2_k127_4038834_0 PFAM Radical SAM domain protein K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 398.0
CMS2_k127_4038834_1 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007648 287.0
CMS2_k127_4051448_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 377.0
CMS2_k127_4051448_1 DUF35 OB-fold domain, acyl-CoA-associated K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000008939 269.0
CMS2_k127_4070898_0 Belongs to the thiolase family K07550 - - 1.17e-198 627.0
CMS2_k127_4070898_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 344.0
CMS2_k127_4083338_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0 1004.0
CMS2_k127_4083338_1 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 381.0
CMS2_k127_4083338_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000003289 106.0
CMS2_k127_4083338_3 redox-active disulfide protein 2 - - - 0.00000000000332 70.0
CMS2_k127_4084945_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 351.0
CMS2_k127_4084945_1 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000008154 162.0
CMS2_k127_4084945_2 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.00000000000000000000000000000002093 132.0
CMS2_k127_4084945_3 L-threonylcarbamoyladenylate synthase K01104,K07566 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87,3.1.3.48 0.0000000000000000000000000004866 115.0
CMS2_k127_4128977_0 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 346.0
CMS2_k127_4128977_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000001128 188.0
CMS2_k127_4128977_2 Histidine kinase - - - 0.000000000000000000000000000000001504 135.0
CMS2_k127_4150883_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 382.0
CMS2_k127_4150883_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 374.0
CMS2_k127_4150883_2 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 359.0
CMS2_k127_4150883_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000001519 223.0
CMS2_k127_4211025_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 535.0
CMS2_k127_4211025_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 439.0
CMS2_k127_4211025_2 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000001018 241.0
CMS2_k127_4211025_3 TIGRFAM MoaD family protein K03636 - - 0.00006473 53.0
CMS2_k127_421330_0 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 397.0
CMS2_k127_421330_1 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.0000000000000000000000000001298 122.0
CMS2_k127_421330_2 PFAM NAD dependent epimerase dehydratase family - - - 0.00000000000000000000001214 106.0
CMS2_k127_4227165_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 6.969e-267 834.0
CMS2_k127_4227165_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008661 259.0
CMS2_k127_4227165_2 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000001747 165.0
CMS2_k127_4237466_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008848 303.0
CMS2_k127_4237466_1 Domain of unknown function (DUF932) - - - 0.00000000000000000000000000001068 128.0
CMS2_k127_4246994_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 8.745e-266 837.0
CMS2_k127_4246994_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 475.0
CMS2_k127_4246994_2 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000009411 241.0
CMS2_k127_4246994_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000002116 107.0
CMS2_k127_4254473_0 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000009587 190.0
CMS2_k127_4254473_1 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.00000000000004479 74.0
CMS2_k127_4261010_0 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000644 262.0
CMS2_k127_4282331_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 400.0
CMS2_k127_4283011_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 425.0
CMS2_k127_4283011_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000003559 220.0
CMS2_k127_4283011_2 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000002291 128.0
CMS2_k127_4283011_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 0.000000000000000000000000000004424 123.0
CMS2_k127_4283011_4 Xylose isomerase domain protein TIM barrel - - - 0.00009355 52.0
CMS2_k127_4297512_0 FAD dependent oxidoreductase K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 462.0
CMS2_k127_4297512_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008467 245.0
CMS2_k127_4297512_2 Maf-like protein K06287 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0022402,GO:0022607,GO:0030428,GO:0032506,GO:0044085,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0090529,GO:1902410,GO:1903047 - 0.000000000000000000000000000000000000000000000000003881 187.0
CMS2_k127_4297512_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.000000000000000000000000000000000001351 154.0
CMS2_k127_4297512_4 Calcineurin-like phosphoesterase - - - 0.00000000000000000000001108 110.0
CMS2_k127_4297512_5 Pyridoxamine 5'-phosphate oxidase like - - - 0.0000000000002273 76.0
CMS2_k127_4311582_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000001781 207.0
CMS2_k127_4311582_1 Serine aminopeptidase, S33 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000002634 129.0
CMS2_k127_4327866_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 606.0
CMS2_k127_4327866_1 3-hydroxyacyl-CoA dehydrogenase K15016 - 1.1.1.35,4.2.1.17 0.0000000000000000000000000005844 116.0
CMS2_k127_4329987_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 391.0
CMS2_k127_4329987_1 domain HDIG-containing protein K06951 - - 0.00000000000000000000000000000000000000000000000000000000111 204.0
CMS2_k127_4330483_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 607.0
CMS2_k127_4359512_0 TIGRFAM geranylgeranyl reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001365 250.0
CMS2_k127_4359512_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000001905 155.0
CMS2_k127_4359512_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000354 145.0
CMS2_k127_4408738_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 503.0
CMS2_k127_4408738_1 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 467.0
CMS2_k127_4408738_2 PFAM iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009063 434.0
CMS2_k127_4408738_3 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 436.0
CMS2_k127_4408738_4 Coenzyme A transferase K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000818 249.0
CMS2_k127_4408738_5 Succinyl-CoA 3-ketoacid-CoA transferase K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000001139 207.0
CMS2_k127_4408738_6 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000004029 141.0
CMS2_k127_4408738_7 choline dehydrogenase activity - - - 0.00000000000000000000000000032 115.0
CMS2_k127_4408738_8 4Fe-4S dicluster domain - - - 0.00000000000001463 83.0
CMS2_k127_4412694_0 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001566 273.0
CMS2_k127_4412694_1 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000000000005581 172.0
CMS2_k127_4412694_2 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000001622 106.0
CMS2_k127_4412694_3 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000008261 96.0
CMS2_k127_4412694_4 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000001354 77.0
CMS2_k127_441461_0 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 387.0
CMS2_k127_4425601_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000003421 192.0
CMS2_k127_4432173_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 550.0
CMS2_k127_4432173_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 320.0
CMS2_k127_4432173_2 4Fe-4S single cluster domain of Ferredoxin I - - - 0.0000000007082 63.0
CMS2_k127_4457666_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004611 241.0
CMS2_k127_4457666_1 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000002195 241.0
CMS2_k127_4457666_2 PFAM Glycosyl transferase family 2 K14597 - - 0.0000000000000000000000000001873 121.0
CMS2_k127_4457666_3 Transcription factor zinc-finger K09981 - - 0.00000000000003931 79.0
CMS2_k127_4552921_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 508.0
CMS2_k127_4552921_1 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 292.0
CMS2_k127_4552921_2 Transcriptional regulator - - - 0.0000000000000000000000000000000001313 136.0
CMS2_k127_4584912_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 540.0
CMS2_k127_4584912_1 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 415.0
CMS2_k127_4584912_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000009753 147.0
CMS2_k127_4586485_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 300.0
CMS2_k127_4586485_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009015 283.0
CMS2_k127_4586485_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001073 191.0
CMS2_k127_461980_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 4.836e-262 832.0
CMS2_k127_461980_1 Formate dehydrogenase iron-sulfur subunit K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003046 257.0
CMS2_k127_461980_2 PFAM molybdopterin oxidoreductase Fe4S4 region K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000004331 204.0
CMS2_k127_461980_3 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000002562 143.0
CMS2_k127_4649323_0 UDP-glucose 4-epimerase activity K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 370.0
CMS2_k127_4649323_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000003164 196.0
CMS2_k127_4649323_2 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000001152 151.0
CMS2_k127_4649323_3 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000001348 89.0
CMS2_k127_4649323_4 GtrA-like protein - - - 0.0000002079 59.0
CMS2_k127_4649744_0 Protein of unknown function (DUF2089) - - - 0.000000000000000000000000000000000000000001258 158.0
CMS2_k127_4649744_1 - - - - 0.000000000000000000000000006018 117.0
CMS2_k127_4649744_2 - - - - 0.0000000001803 62.0
CMS2_k127_4649744_3 - - - - 0.0000002827 57.0
CMS2_k127_4649744_4 methyltransferase - - - 0.0009594 44.0
CMS2_k127_4654199_0 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000001169 193.0
CMS2_k127_4661118_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 382.0
CMS2_k127_4661118_1 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 343.0
CMS2_k127_4661118_2 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000002033 189.0
CMS2_k127_4661118_3 Uncharacterized protein family (UPF0051) K07033 - - 0.000000000000000000000000000000000000000000000000007439 185.0
CMS2_k127_4661118_4 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000000000000000000000007498 184.0
CMS2_k127_4661118_5 sulfur carrier activity - - - 0.00000000000000000000002229 103.0
CMS2_k127_4661118_6 - - - - 0.0002036 47.0
CMS2_k127_4666216_0 xylulokinase activity K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000002739 241.0
CMS2_k127_4666216_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000001657 212.0
CMS2_k127_4705321_0 Acyl-CoA thioester hydrolase bile acid-CoA amino acid N-acetyltransferase - - - 0.0000000000000000000000000001942 124.0
CMS2_k127_4705321_1 Protein of unknown function (DUF2934) - - - 0.0000879 45.0
CMS2_k127_4715676_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.261e-246 778.0
CMS2_k127_4715676_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.162e-206 649.0
CMS2_k127_4715676_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000003594 205.0
CMS2_k127_4715676_3 Recombinase zinc beta ribbon domain - - - 0.0005787 45.0
CMS2_k127_4716167_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 554.0
CMS2_k127_4716167_1 acyl-coa dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 541.0
CMS2_k127_4716167_10 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001444 254.0
CMS2_k127_4716167_11 formate C-acetyltransferase glycine radical K00656,K20038 - 2.3.1.54,4.3.99.4 0.00000000000000000000000000000000000000000000000000002818 203.0
CMS2_k127_4716167_12 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000002429 197.0
CMS2_k127_4716167_13 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000002466 175.0
CMS2_k127_4716167_14 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000004482 174.0
CMS2_k127_4716167_15 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000000000006607 171.0
CMS2_k127_4716167_16 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000008877 115.0
CMS2_k127_4716167_17 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000008739 107.0
CMS2_k127_4716167_18 Helix-turn-helix XRE-family like proteins - - - 0.000000009478 66.0
CMS2_k127_4716167_19 helix_turn_helix, Lux Regulon - - - 0.00000001684 66.0
CMS2_k127_4716167_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 444.0
CMS2_k127_4716167_3 lipid-transfer protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 421.0
CMS2_k127_4716167_4 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 358.0
CMS2_k127_4716167_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 368.0
CMS2_k127_4716167_6 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 352.0
CMS2_k127_4716167_7 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009651 331.0
CMS2_k127_4716167_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001361 286.0
CMS2_k127_4716167_9 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008517 284.0
CMS2_k127_4717229_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000007203 187.0
CMS2_k127_4717229_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03117 - - 0.000000382 58.0
CMS2_k127_4717229_2 zinc-ribbon domain - - - 0.0002758 45.0
CMS2_k127_4719379_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 311.0
CMS2_k127_4719379_1 Belongs to the glycosyl hydrolase 30 family - GO:0005575,GO:0005576 - 0.000191 54.0
CMS2_k127_4719592_0 PFAM Integrase, catalytic core K07497 - - 0.000000000001379 79.0
CMS2_k127_4719592_1 Transposase IS116/IS110/IS902 family - - - 0.00000000001349 72.0
CMS2_k127_4719592_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000002117 61.0
CMS2_k127_4727302_0 Thermophilic metalloprotease (M29) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 503.0
CMS2_k127_4727302_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007551 410.0
CMS2_k127_4727302_2 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 418.0
CMS2_k127_4727302_3 PFAM Isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000002383 220.0
CMS2_k127_4727302_4 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000001624 194.0
CMS2_k127_4727302_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000295 178.0
CMS2_k127_4727302_6 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000000000000000000009327 113.0
CMS2_k127_4727302_7 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000005008 85.0
CMS2_k127_4727302_8 - - - - 0.0000000000001063 74.0
CMS2_k127_4727302_9 - - - - 0.0001663 53.0
CMS2_k127_4730693_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 515.0
CMS2_k127_4730693_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 466.0
CMS2_k127_4730693_2 Myo-inositol-1-phosphate synthase, GAPDH domain protein K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 385.0
CMS2_k127_4730693_3 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 349.0
CMS2_k127_4730693_4 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000003665 156.0
CMS2_k127_4775727_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 315.0
CMS2_k127_4775727_1 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000000000000000000000000001196 124.0
CMS2_k127_4790441_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000004791 195.0
CMS2_k127_4790441_1 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000005767 111.0
CMS2_k127_4799776_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 306.0
CMS2_k127_4799776_1 Winged helix-turn-helix - - - 0.000000000000000001032 97.0
CMS2_k127_4812858_0 chorismate binding enzyme K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000001532 235.0
CMS2_k127_4812858_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000005264 116.0
CMS2_k127_4831764_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.287e-219 690.0
CMS2_k127_4831764_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.256e-216 679.0
CMS2_k127_4831764_10 Ribonuclease R winged-helix domain protein K09720 - - 0.000000000000000008304 86.0
CMS2_k127_4831764_2 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 552.0
CMS2_k127_4831764_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 522.0
CMS2_k127_4831764_4 Binding-protein-dependent transport system inner membrane component K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 371.0
CMS2_k127_4831764_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 359.0
CMS2_k127_4831764_6 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 293.0
CMS2_k127_4831764_7 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001326 266.0
CMS2_k127_4831764_8 Nitrogen regulatory protein P-II K04751 - - 0.0000000000000000000000000000000000000003206 151.0
CMS2_k127_4831764_9 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.0000000000000000000000000000000000001591 155.0
CMS2_k127_4833268_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 1.544e-293 910.0
CMS2_k127_4833268_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 425.0
CMS2_k127_4833268_2 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004576 285.0
CMS2_k127_4833268_3 uracil phosphoribosyltransferase activity K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000000000002711 79.0
CMS2_k127_4856012_0 HELICc2 K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 374.0
CMS2_k127_4856012_1 Poly A polymerase head domain K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 317.0
CMS2_k127_4856012_2 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000004025 162.0
CMS2_k127_4856012_3 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000005721 143.0
CMS2_k127_485772_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 594.0
CMS2_k127_485772_1 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 308.0
CMS2_k127_485772_2 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000001168 190.0
CMS2_k127_4877227_0 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 302.0
CMS2_k127_4877227_1 PFAM Translin K07477 - - 0.0000000000000000000000000000000000000000000000000000001646 203.0
CMS2_k127_4877227_2 glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.000000000000000000000000002549 113.0
CMS2_k127_4877227_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000003165 62.0
CMS2_k127_4885750_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 438.0
CMS2_k127_4885750_1 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 419.0
CMS2_k127_4885750_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.0000000000001071 73.0
CMS2_k127_488946_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000554 180.0
CMS2_k127_488946_1 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.000000000000000000000000000000000001363 149.0
CMS2_k127_4894160_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 540.0
CMS2_k127_4894160_1 PD-(D/E)XK nuclease superfamily K03582,K16898 - 3.1.11.5,3.6.4.12 0.0000000000000000000000000000000000000000000000000000002213 207.0
CMS2_k127_4899505_0 PFAM molybdopterin oxidoreductase K00123,K05299 - 1.17.1.10,1.17.1.9 1.572e-208 661.0
CMS2_k127_4899505_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007102 563.0
CMS2_k127_4899505_2 Molybdopterin oxidoreductase Fe4S4 domain K00336,K05299 - 1.17.1.10,1.6.5.3 0.00000000000000000000000000000000000000000000000000000001266 201.0
CMS2_k127_4916159_0 Pyridine nucleotide-disulphide oxidoreductase - - - 3.266e-262 833.0
CMS2_k127_4916159_1 Sodium Bile acid symporter family K03325 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 514.0
CMS2_k127_4916159_10 ThiS family K03636 - - 0.00003883 50.0
CMS2_k127_4916159_2 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 412.0
CMS2_k127_4916159_3 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 403.0
CMS2_k127_4916159_4 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000004623 223.0
CMS2_k127_4916159_5 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.00000000000000000000000000000000000000000000136 176.0
CMS2_k127_4916159_6 PFAM Thioredoxin K03671 - - 0.000000000000000000000001604 108.0
CMS2_k127_4916159_7 PFAM Thioredoxin K03671 - - 0.000000000000000001527 90.0
CMS2_k127_4916159_8 Putative Fe-S cluster - - - 0.000000002654 68.0
CMS2_k127_4916159_9 PFAM Methylamine utilisation protein MauE - - - 0.0000005113 61.0
CMS2_k127_4917748_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 569.0
CMS2_k127_4917748_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 542.0
CMS2_k127_4917748_2 arginine biosynthetic process via ornithine K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 443.0
CMS2_k127_4917748_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000009664 150.0
CMS2_k127_4925770_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000008474 198.0
CMS2_k127_4925770_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000004037 159.0
CMS2_k127_4925770_2 PFAM response regulator receiver - - - 0.0000000000000000000000002427 110.0
CMS2_k127_4956661_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 317.0
CMS2_k127_4956661_1 PAC2 family - - - 0.000000000000000000000000000000000000000000000000000000000003136 214.0
CMS2_k127_4966403_0 carbon-monoxide dehydrogenase (ferredoxin) activity K00192,K02572,K02573,K14138 - 1.2.7.4,2.3.1.169 2.575e-274 856.0
CMS2_k127_4966403_1 Pterin binding enzyme K15023 - 2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 349.0
CMS2_k127_4966403_2 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 308.0
CMS2_k127_4979041_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 5.646e-270 856.0
CMS2_k127_4979041_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 329.0
CMS2_k127_4979041_2 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 319.0
CMS2_k127_4979041_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000302 258.0
CMS2_k127_4979041_4 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000003199 189.0
CMS2_k127_4979041_5 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000003742 169.0
CMS2_k127_4993310_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 376.0
CMS2_k127_4993310_1 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.000000000000000000001244 108.0
CMS2_k127_4993310_2 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000001537 88.0
CMS2_k127_4993310_3 DNA polymerase III, delta subunit K02341 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000003649 79.0
CMS2_k127_4998030_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001105 256.0
CMS2_k127_4998030_1 HD domain - - - 0.0000000000000000000000000000000000000002534 161.0
CMS2_k127_4998030_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000006326 100.0
CMS2_k127_5010065_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 459.0
CMS2_k127_5010065_1 CO dehydrogenase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 292.0
CMS2_k127_5010065_2 cellulose 1,4-beta-cellobiosidase activity - - - 0.000000000000004407 89.0
CMS2_k127_5010065_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000001941 66.0
CMS2_k127_5010065_4 COG1520 FOG WD40-like repeat - - - 0.00000000003425 76.0
CMS2_k127_5023573_0 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 299.0
CMS2_k127_5023573_1 transmembrane transport K01992 - - 0.000000000000000000000000000000000003614 148.0
CMS2_k127_5023573_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000007625 139.0
CMS2_k127_5023573_3 RDD family - - - 0.000000000000000000000008135 111.0
CMS2_k127_5023573_4 HEAT repeat - - - 0.000000000000008867 78.0
CMS2_k127_5035226_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.06e-257 806.0
CMS2_k127_5035226_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000321 286.0
CMS2_k127_5035226_2 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000003471 87.0
CMS2_k127_507054_0 MscS Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000003471 228.0
CMS2_k127_507054_1 TFIIE alpha subunit - - - 0.00000000000000000000000000002746 121.0
CMS2_k127_507054_2 Bacterial Ig-like domain - - - 0.0000000000000000000000002758 123.0
CMS2_k127_507054_3 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000001641 79.0
CMS2_k127_507054_4 Bacterial Ig-like domain (group 1) - - - 0.00000000000001664 87.0
CMS2_k127_507054_5 Short C-terminal domain K08982 - - 0.0000000001919 64.0
CMS2_k127_5085502_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000004515 268.0
CMS2_k127_5085502_1 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000001094 94.0
CMS2_k127_5085502_2 DNA polymerase III K02340 - 2.7.7.7 0.0000000000000001407 89.0
CMS2_k127_510045_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 8.21e-234 739.0
CMS2_k127_510045_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 293.0
CMS2_k127_510045_2 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000003117 147.0
CMS2_k127_5125353_0 Glycosyltransferase family 20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 608.0
CMS2_k127_5125353_1 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000008735 102.0
CMS2_k127_5125353_2 Transporter, CPA2 family - - - 0.0000000000000008124 91.0
CMS2_k127_514890_0 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 314.0
CMS2_k127_514890_1 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005381 283.0
CMS2_k127_514890_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000004484 256.0
CMS2_k127_514890_3 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000004905 168.0
CMS2_k127_514890_4 SnoaL-like domain - - - 0.0000000000000000000000000000001381 130.0
CMS2_k127_514890_5 Alpha/beta hydrolase family K06889,K07397 - - 0.0000000000001077 73.0
CMS2_k127_514890_6 Putative regulatory protein - - - 0.00000000002129 67.0
CMS2_k127_514890_7 Acetyltransferase (GNAT) domain - - - 0.00000156 60.0
CMS2_k127_5156107_0 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 389.0
CMS2_k127_5156107_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000144 295.0
CMS2_k127_5156107_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000001569 179.0
CMS2_k127_5156107_3 FAD dependent oxidoreductase - - - 0.00000000004744 70.0
CMS2_k127_5212245_0 PFAM glycosyl transferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 308.0
CMS2_k127_5215672_0 FAD binding domain K16051 - 1.3.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 475.0
CMS2_k127_5215672_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 396.0
CMS2_k127_5215672_2 CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000003589 244.0
CMS2_k127_5215672_3 Belongs to the peptidase M50B family - - - 0.000000000000000000000005079 109.0
CMS2_k127_5226737_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 542.0
CMS2_k127_5226737_1 nucleotidyl transferase K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000007699 155.0
CMS2_k127_5242350_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008872 519.0
CMS2_k127_5242350_1 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 422.0
CMS2_k127_5242350_2 KR domain - - - 0.0000000000000000000000000000000000000000000006359 174.0
CMS2_k127_5243808_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 528.0
CMS2_k127_5243808_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007888 488.0
CMS2_k127_5243808_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 425.0
CMS2_k127_5243808_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 392.0
CMS2_k127_5243808_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 299.0
CMS2_k127_5243808_5 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000003787 220.0
CMS2_k127_5243808_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000001527 213.0
CMS2_k127_5243840_0 Putative esterase K07017 - - 0.000000000000000000000005645 106.0
CMS2_k127_5243840_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000005222 57.0
CMS2_k127_5296025_0 CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000331 263.0
CMS2_k127_5296025_1 A transferase subunit A K01028,K01034 - 2.8.3.5,2.8.3.8,2.8.3.9 0.000000000000005526 79.0
CMS2_k127_531423_0 acetone carboxylase, alpha subunit K10854 - 6.4.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 463.0
CMS2_k127_531423_1 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000013 158.0
CMS2_k127_5315539_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.281e-228 717.0
CMS2_k127_5315539_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000005831 229.0
CMS2_k127_5315539_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000003412 61.0
CMS2_k127_5338540_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 324.0
CMS2_k127_5338540_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000001708 159.0
CMS2_k127_5343975_0 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000001311 197.0
CMS2_k127_5343975_1 B12 binding domain - - - 0.00000000000000006049 82.0
CMS2_k127_5343975_2 ig-like, plexins, transcription factors - - - 0.00007719 51.0
CMS2_k127_5346952_0 decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 316.0
CMS2_k127_5346952_1 CoA carboxylase activity K01615,K01965,K02160,K17490 - 2.1.3.1,4.1.1.70,6.4.1.3 0.000000000000000000007134 99.0
CMS2_k127_5392233_0 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 611.0
CMS2_k127_5392233_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000002649 176.0
CMS2_k127_5392233_2 ferredoxin iron-sulfur binding - - - 0.000000000000000000000000000002451 124.0
CMS2_k127_5397868_0 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 361.0
CMS2_k127_5397868_1 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000000000006148 202.0
CMS2_k127_5397868_2 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000762 159.0
CMS2_k127_5404828_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 361.0
CMS2_k127_5404828_1 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008187 237.0
CMS2_k127_5404828_2 - - - - 0.0000000000000000000000000000000000000000000000000004257 191.0
CMS2_k127_5404828_3 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - - 0.0000000000000000000000000000000000000000000001084 179.0
CMS2_k127_5404828_4 AAA domain K03546 - - 0.000000000000000000001394 96.0
CMS2_k127_5404828_5 PFAM ABC transporter related K01990 - - 0.0000000000001598 71.0
CMS2_k127_5404828_6 Cell wall-active antibiotics response 4TMS YvqF - - - 0.0001107 49.0
CMS2_k127_5408469_0 all-trans-retinol 13,14-reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 561.0
CMS2_k127_5408469_1 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000001737 211.0
CMS2_k127_5408469_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000004168 182.0
CMS2_k127_5408469_4 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000000000000006601 144.0
CMS2_k127_5408469_5 alpha-L-arabinofuranosidase - - - 0.00008467 50.0
CMS2_k127_5431457_0 Magnesium chelatase, subunit ChlI K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 447.0
CMS2_k127_5431457_1 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000411 261.0
CMS2_k127_5431457_2 - - - - 0.0000000000001725 72.0
CMS2_k127_5431457_3 Belongs to the UPF0235 family K09131 - - 0.00000000000115 73.0
CMS2_k127_5431457_4 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.00002439 47.0
CMS2_k127_5470326_0 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000008844 237.0
CMS2_k127_5470326_1 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000001216 219.0
CMS2_k127_5470326_2 Winged helix-turn-helix - - - 0.00000000000000000000002576 103.0
CMS2_k127_5470326_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000005705 70.0
CMS2_k127_5515767_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000006336 244.0
CMS2_k127_5515767_1 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000000000000000002181 224.0
CMS2_k127_5515767_2 Belongs to the universal stress protein A family - - - 0.00000000000000007632 89.0
CMS2_k127_5543026_0 to GB L77117 PID 1592180 percent identity K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 448.0
CMS2_k127_5543026_1 PFAM Prokaryotic protein of K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 342.0
CMS2_k127_5543026_2 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.000000000000000000000000000000000001685 146.0
CMS2_k127_5543026_3 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000221 131.0
CMS2_k127_5580192_0 leucyl-tRNA aminoacylation K01869 - 6.1.1.4 0.0 1092.0
CMS2_k127_558053_0 Protein conserved in bacteria - - - 0.000000000000000000000000000001184 131.0
CMS2_k127_558053_1 PBS lyase HEAT-like repeat - - - 0.000000000000000000004329 98.0
CMS2_k127_558053_2 transferase activity, transferring glycosyl groups - - - 0.0000004147 56.0
CMS2_k127_5582183_0 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004393 285.0
CMS2_k127_5582183_1 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000008107 212.0
CMS2_k127_5582183_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000002371 156.0
CMS2_k127_5582183_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000005988 102.0
CMS2_k127_5600632_0 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002933 267.0
CMS2_k127_5608899_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 6.186e-201 638.0
CMS2_k127_5608899_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 481.0
CMS2_k127_5608899_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 452.0
CMS2_k127_5608899_3 PFAM GPR1 FUN34 yaaH family K07034 - - 0.00000000000000000000001325 103.0
CMS2_k127_5624619_0 GH3 auxin-responsive promoter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 422.0
CMS2_k127_5624619_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 319.0
CMS2_k127_5624619_2 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000000000001142 145.0
CMS2_k127_5624619_3 Hypothethical protein - - - 0.0000000000007607 68.0
CMS2_k127_5630726_0 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 333.0
CMS2_k127_5630726_1 Ethyl tert-butyl ether degradation EthD - - - 0.0000000000000000000002184 100.0
CMS2_k127_5630726_2 TM2 domain protein - - - 0.000000000000001691 80.0
CMS2_k127_5630726_3 COG1520 FOG WD40-like repeat K17713 - - 0.000000003446 68.0
CMS2_k127_5649770_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003572 289.0
CMS2_k127_5649770_1 aminopeptidase activity K09612,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.10,3.4.11.24,3.4.11.6 0.000000000000001427 86.0
CMS2_k127_5691642_0 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 411.0
CMS2_k127_5691642_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006584 279.0
CMS2_k127_5757422_0 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000001344 248.0
CMS2_k127_5757422_1 KR domain K07124 - - 0.000000008293 61.0
CMS2_k127_5759210_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 398.0
CMS2_k127_5759210_1 PFAM Appr-1-p processing - - - 0.0000000000000000000000000000000000000000000000000000000000001042 218.0
CMS2_k127_5759210_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000008184 196.0
CMS2_k127_5759210_3 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000002917 167.0
CMS2_k127_5812120_0 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001951 229.0
CMS2_k127_5812120_1 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000001757 161.0
CMS2_k127_5815350_0 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000007425 228.0
CMS2_k127_5815350_1 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000004452 81.0
CMS2_k127_5830386_0 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 334.0
CMS2_k127_5830386_1 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000004719 101.0
CMS2_k127_5841765_0 Heat shock 70 kDa protein K04043 - - 1.037e-284 886.0
CMS2_k127_5841765_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000006025 219.0
CMS2_k127_5841765_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000001545 148.0
CMS2_k127_588011_0 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 339.0
CMS2_k127_588011_1 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000006395 222.0
CMS2_k127_588011_2 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.000000000000000000000000000000000000001545 153.0
CMS2_k127_588011_3 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0071704,GO:0072329,GO:1901575 2.1.3.15,6.4.1.3 0.00000000000000000000001207 100.0
CMS2_k127_588011_4 - - - - 0.000000000262 65.0
CMS2_k127_588664_0 Glycine radical K00656 - 2.3.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 523.0
CMS2_k127_588664_1 Helix-turn-helix domain K07729 - - 0.000000000000000000002043 95.0
CMS2_k127_5920749_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.32e-247 774.0
CMS2_k127_5920749_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 584.0
CMS2_k127_5920749_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 324.0
CMS2_k127_5920749_3 acyl-CoA transferases carnitine dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 302.0
CMS2_k127_5920749_4 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000001099 253.0
CMS2_k127_5920749_5 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004674 249.0
CMS2_k127_5920749_6 MoaE protein K03635,K21142 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016782,GO:0016783,GO:0018130,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0030366,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.8.1.12 0.000000000000000000000001388 107.0
CMS2_k127_5930615_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 299.0
CMS2_k127_5930615_1 PAS domain - - - 0.0000000000000000000000000000000000001574 162.0
CMS2_k127_5930615_2 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000005173 109.0
CMS2_k127_5951373_0 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000001671 196.0
CMS2_k127_5951373_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000005833 190.0
CMS2_k127_5951373_2 PFAM Acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000009826 165.0
CMS2_k127_595551_0 FMN binding - - - 9.326e-243 759.0
CMS2_k127_595551_1 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 336.0
CMS2_k127_595551_2 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 332.0
CMS2_k127_5960051_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000002591 222.0
CMS2_k127_5960051_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000001643 213.0
CMS2_k127_5960051_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000006742 136.0
CMS2_k127_5960051_3 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000005569 99.0
CMS2_k127_5960051_4 Belongs to the UPF0109 family K06960 - - 0.00000000000000004404 83.0
CMS2_k127_5960051_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000002391 78.0
CMS2_k127_5986574_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.124e-234 735.0
CMS2_k127_5986574_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 466.0
CMS2_k127_5986574_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000002696 255.0
CMS2_k127_5986574_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000003119 237.0
CMS2_k127_5986574_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000009045 106.0
CMS2_k127_5986574_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000005658 66.0
CMS2_k127_6010954_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000008692 195.0
CMS2_k127_6010954_1 ABC ferric siderophore transporter, ATPase subunit K02013 - 3.6.3.34 0.00000000000000000000000000000001642 144.0
CMS2_k127_6045688_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 526.0
CMS2_k127_6045688_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 301.0
CMS2_k127_6045688_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005766 278.0
CMS2_k127_6045688_3 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004689 276.0
CMS2_k127_6045688_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000002519 226.0
CMS2_k127_6045688_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000001182 190.0
CMS2_k127_6045688_6 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000000000471 172.0
CMS2_k127_6045688_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000006079 130.0
CMS2_k127_6045688_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000003401 73.0
CMS2_k127_6045688_9 PFAM Colicin V production protein K03558 - - 0.000001531 56.0
CMS2_k127_6072331_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.632e-284 885.0
CMS2_k127_6072331_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 575.0
CMS2_k127_6072331_2 PFAM molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 360.0
CMS2_k127_6072331_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001844 265.0
CMS2_k127_6072331_4 Prephenate dehydratase K04518 - 4.2.1.51 0.00000000000000000008614 91.0
CMS2_k127_6079338_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 4.021e-197 627.0
CMS2_k127_6079338_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 538.0
CMS2_k127_6079338_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 459.0
CMS2_k127_6079338_3 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009722 445.0
CMS2_k127_6079338_4 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 419.0
CMS2_k127_6079338_5 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000003889 211.0
CMS2_k127_6079338_6 Isochorismatase family - - - 0.000000000000000000000000000000000000568 159.0
CMS2_k127_6079338_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000004648 131.0
CMS2_k127_6079338_8 GtrA-like protein K00721 - 2.4.1.83 0.0002103 45.0
CMS2_k127_6080585_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 578.0
CMS2_k127_6107046_0 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000002677 220.0
CMS2_k127_6107046_1 Conserved carboxylase domain K01960 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000001471 208.0
CMS2_k127_6107046_2 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000001863 199.0
CMS2_k127_6107046_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000003771 191.0
CMS2_k127_6107046_4 - - - - 0.000000000000000000000000002759 112.0
CMS2_k127_6119303_0 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 348.0
CMS2_k127_6119303_1 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 301.0
CMS2_k127_6119303_2 Anthranilate synthase component I, N terminal region K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000002627 259.0
CMS2_k127_6119303_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000001366 249.0
CMS2_k127_6119303_4 Amino-transferase class IV - - - 0.000000000000000000000000000000000000000000000000000000000000000008433 235.0
CMS2_k127_6127083_0 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 510.0
CMS2_k127_6127083_1 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000003634 216.0
CMS2_k127_6127083_2 PAC2 family K07159 - - 0.0000000000000000000000003998 109.0
CMS2_k127_6128633_0 including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000753 257.0
CMS2_k127_6128633_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000001817 149.0
CMS2_k127_6140973_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003074 256.0
CMS2_k127_6142299_0 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000003829 254.0
CMS2_k127_6142299_1 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01031 - 2.8.3.6 0.0000000000000000000000000000000000000000000000000003586 189.0
CMS2_k127_6142299_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000009424 117.0
CMS2_k127_6145204_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000001181 187.0
CMS2_k127_6145204_1 - - - - 0.00000000000000000000001743 102.0
CMS2_k127_6145204_3 - - - - 0.00007138 47.0
CMS2_k127_6149090_0 Patatin-like phospholipase K07001 GO:0003674,GO:0003824,GO:0016787 - 0.0000000000000000000000000000000000000000000000000002618 199.0
CMS2_k127_6149090_1 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000006124 124.0
CMS2_k127_6149090_2 Dodecin K09165 - - 0.000000000000000000000001097 105.0
CMS2_k127_6163464_0 Aldehyde dehydrogenase family K00131 - 1.2.1.9 0.00000000000000000000000000000000000000211 148.0
CMS2_k127_6163464_1 RDD family - - - 0.0000000000000000000000000000000000244 141.0
CMS2_k127_6163464_2 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000162 139.0
CMS2_k127_6187449_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1063.0
CMS2_k127_6187449_1 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 362.0
CMS2_k127_6194588_0 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 588.0
CMS2_k127_6194588_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000007394 254.0
CMS2_k127_6194588_2 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000008005 217.0
CMS2_k127_6194588_3 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000785 159.0
CMS2_k127_6194588_4 Pfam:Pyridox_oxidase - - - 0.00000000000000000000000000000000004051 139.0
CMS2_k127_6194588_5 nucleoside-diphosphate sugar epimerase K07071 - - 0.00001094 48.0
CMS2_k127_6211770_0 ERG2 and Sigma1 receptor like protein K20719 - - 0.000000000000000000000000000000000001391 145.0
CMS2_k127_6211770_1 light absorption - - - 0.000000000000000000114 94.0
CMS2_k127_6215300_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 342.0
CMS2_k127_6215300_1 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001735 254.0
CMS2_k127_6215300_2 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000002497 222.0
CMS2_k127_6215300_3 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000003431 52.0
CMS2_k127_6233898_0 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 430.0
CMS2_k127_6233898_1 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002643 264.0
CMS2_k127_6233898_2 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000000003851 162.0
CMS2_k127_6233898_3 EthD domain - - - 0.000000001013 68.0
CMS2_k127_6233898_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000001053 54.0
CMS2_k127_6233898_5 TFIIE alpha subunit - - - 0.0006317 43.0
CMS2_k127_6245052_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 9.701e-203 634.0
CMS2_k127_6245052_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 370.0
CMS2_k127_6254766_0 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002485 269.0
CMS2_k127_6254766_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000001138 241.0
CMS2_k127_6262299_0 Nitrite and sulphite reductase 4Fe-4S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002393 287.0
CMS2_k127_6262299_1 PFAM Cysteine-rich domain K11473 - - 0.0000000001292 68.0
CMS2_k127_6271812_0 PFAM glycoside hydrolase family 3 domain protein K05349 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000004866 225.0
CMS2_k127_6271812_1 GCN5 family acetyltransferase K22477 - 2.3.1.1 0.000000000000000000000000000000000000008798 151.0
CMS2_k127_6271812_2 Gaf domain - - - 0.000000000000000000000000000000005303 134.0
CMS2_k127_6271812_3 Dolichol kinase - - - 0.0000000000003239 78.0
CMS2_k127_6280812_0 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000002026 131.0
CMS2_k127_6280812_1 FAD dependent oxidoreductase - - - 0.00000000000000000000002272 111.0
CMS2_k127_6280812_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000007944 60.0
CMS2_k127_6280812_3 Nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00006585 52.0
CMS2_k127_6284083_0 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.0000000000000000000000000000000000000009521 150.0
CMS2_k127_6284083_1 CoA binding domain - - - 0.0000000000000000000000000000000000286 141.0
CMS2_k127_6284083_2 - - - - 0.00000000000000000000000689 111.0
CMS2_k127_6284083_3 Metallo-beta-lactamase superfamily K17837 - 3.5.2.6 0.0003269 51.0
CMS2_k127_6284090_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 569.0
CMS2_k127_6284090_1 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 332.0
CMS2_k127_6284090_2 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 304.0
CMS2_k127_6300831_0 DNA modification repair radical SAM protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 361.0
CMS2_k127_6300831_1 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 332.0
CMS2_k127_6300831_2 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000002985 171.0
CMS2_k127_6335949_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 601.0
CMS2_k127_6335949_1 - - - - 0.000000000000000000000000000000000000000000000000000000000003043 217.0
CMS2_k127_6335949_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000004758 164.0
CMS2_k127_6336450_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1510.0
CMS2_k127_6336450_1 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000185 248.0
CMS2_k127_6340847_0 PFAM Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 366.0
CMS2_k127_6340847_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 302.0
CMS2_k127_6340847_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000009558 230.0
CMS2_k127_6340847_3 Electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000001424 100.0
CMS2_k127_6356860_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 343.0
CMS2_k127_6356860_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000002175 200.0
CMS2_k127_6356860_2 tRNA nucleotidyltransferase domain 2 putative K00970 - 2.7.7.19 0.0000000000000000006842 92.0
CMS2_k127_6384652_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000007067 208.0
CMS2_k127_6384652_1 - - - - 0.00000000000004418 80.0
CMS2_k127_6384652_2 PBS lyase HEAT-like repeat - - - 0.00000000000004646 80.0
CMS2_k127_6390836_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1167.0
CMS2_k127_6390836_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 485.0
CMS2_k127_6390836_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 409.0
CMS2_k127_6390836_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 370.0
CMS2_k127_6390836_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 353.0
CMS2_k127_6390836_5 glycerolipid metabolic process K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 334.0
CMS2_k127_6390836_6 PFAM dihydropteroate synthase, DHPS K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004068 281.0
CMS2_k127_6390836_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000004126 149.0
CMS2_k127_6390836_8 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.0000000000000000000000001954 114.0
CMS2_k127_6390836_9 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family - - - 0.000000006787 58.0
CMS2_k127_6432525_0 Sodium/hydrogen exchanger family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 471.0
CMS2_k127_6432525_1 Ferritin-like domain - - - 0.000000000000004924 82.0
CMS2_k127_6452136_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 554.0
CMS2_k127_6452136_1 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000003136 106.0
CMS2_k127_645578_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 448.0
CMS2_k127_645578_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 406.0
CMS2_k127_645578_2 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000009097 228.0
CMS2_k127_645578_3 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000004868 178.0
CMS2_k127_645578_4 TIGRFAM signal peptidase I, bacterial type K03100 - 3.4.21.89 0.00000000000000000000003277 105.0
CMS2_k127_645578_5 Putative zinc-finger - - - 0.00004371 53.0
CMS2_k127_6458695_0 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000162 175.0
CMS2_k127_6458695_1 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000005483 139.0
CMS2_k127_6458695_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000001775 111.0
CMS2_k127_6484051_0 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004452 283.0
CMS2_k127_6484051_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000001943 200.0
CMS2_k127_6511427_0 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 292.0
CMS2_k127_6511427_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000002587 142.0
CMS2_k127_6511427_2 TM2 domain - - - 0.00000000000000000001342 97.0
CMS2_k127_6518443_1 PFAM PKD domain containing protein - - - 0.00000000000000000003234 100.0
CMS2_k127_6529742_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K05898 - 1.3.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 401.0
CMS2_k127_6529742_1 Pyruvate formate-lyase K00656 - 2.3.1.54 0.000000000000000000000000442 112.0
CMS2_k127_6529742_2 Sterol carrier protein - - - 0.000000000000000004091 91.0
CMS2_k127_6529889_0 Fungal trichothecene efflux pump (TRI12) - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 422.0
CMS2_k127_6529889_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004483 255.0
CMS2_k127_6529889_2 PFAM Archease protein family (DUF101 UPF0211) - - - 0.00000000000000000000000000000002655 130.0
CMS2_k127_6529889_3 GlcNAc-PI de-N-acetylase K22408 - - 0.000000000000000949 87.0
CMS2_k127_6533236_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000003816 200.0
CMS2_k127_6533236_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000001011 159.0
CMS2_k127_6533236_2 heme oxygenase (decyclizing) activity - - - 0.0000000002724 65.0
CMS2_k127_6539450_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000431 201.0
CMS2_k127_6539450_1 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000001156 85.0
CMS2_k127_6539450_2 response regulator - - - 0.0000000003892 72.0
CMS2_k127_6539937_0 metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 291.0
CMS2_k127_6539937_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000001106 151.0
CMS2_k127_6539937_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000363 132.0
CMS2_k127_6596103_0 ATP-dependent peptidase activity K01338 - 3.4.21.53 2.88e-315 983.0
CMS2_k127_6596103_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000244 269.0
CMS2_k127_6596103_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000001044 202.0
CMS2_k127_6596103_3 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000000756 173.0
CMS2_k127_6596103_4 Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000000000000000001092 162.0
CMS2_k127_6596103_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000007633 147.0
CMS2_k127_6596103_6 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000001607 100.0
CMS2_k127_6596103_7 SMART PAS domain containing protein - - - 0.000000000000000001856 100.0
CMS2_k127_660052_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 496.0
CMS2_k127_660052_1 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 288.0
CMS2_k127_660052_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000003681 205.0
CMS2_k127_660052_3 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000006634 203.0
CMS2_k127_660052_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000008543 199.0
CMS2_k127_660052_5 PFAM NAD dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000001149 183.0
CMS2_k127_660052_6 Phytoene dehydrogenase - - - 0.00000000000000000007516 100.0
CMS2_k127_6619582_0 PFAM Cys Met metabolism, pyridoxal phosphate-dependent enzyme K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 507.0
CMS2_k127_6619582_1 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 392.0
CMS2_k127_6619582_2 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000174 85.0
CMS2_k127_6655309_0 Elongation factor G, domain IV K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 478.0
CMS2_k127_6655309_1 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000002857 133.0
CMS2_k127_6659900_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002876 252.0
CMS2_k127_6659900_1 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000803 143.0
CMS2_k127_6659900_2 diguanylate cyclase - - - 0.000000000000001428 86.0
CMS2_k127_6668972_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000005275 220.0
CMS2_k127_6668972_1 belongs to the CobB CobQ family K06873 - - 0.00000000000000000000000000000000000000000000000001044 194.0
CMS2_k127_6668972_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000214 145.0
CMS2_k127_6669708_0 Male sterility protein K21793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002774 498.0
CMS2_k127_6669708_1 - - - - 0.000000001934 67.0
CMS2_k127_6669708_2 NmrA-like family - - - 0.00002947 55.0
CMS2_k127_6686656_0 FAD linked oxidases, C-terminal domain - - - 0.0 1212.0
CMS2_k127_6700542_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002845 269.0
CMS2_k127_6727240_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003708 248.0
CMS2_k127_6727240_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000006253 178.0
CMS2_k127_6727240_2 acetyltransferase - - - 0.0000000000000000000000000000000000000001449 156.0
CMS2_k127_673766_0 NUDIX domain - - - 0.000000000000000000000000000000000000000000006197 171.0
CMS2_k127_673766_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000005909 172.0
CMS2_k127_673766_2 Methyltransferase domain - - - 0.00000000000896 76.0
CMS2_k127_6749534_0 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006697 267.0
CMS2_k127_6749534_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000001064 141.0
CMS2_k127_6752150_0 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 422.0
CMS2_k127_6752150_1 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 359.0
CMS2_k127_6752150_2 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000004011 192.0
CMS2_k127_6752150_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000001021 183.0
CMS2_k127_6752150_4 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000000000824 126.0
CMS2_k127_6754135_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 466.0
CMS2_k127_6754135_1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005622 286.0
CMS2_k127_6754135_2 GYD domain - - - 0.0000000000000000000000000000000001836 134.0
CMS2_k127_6754135_3 HD domain - - - 0.00000000000000005001 96.0
CMS2_k127_6754135_4 Lysophospholipase - GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 - 0.00007186 53.0
CMS2_k127_6757363_0 PFAM Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 429.0
CMS2_k127_6757363_1 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000007265 86.0
CMS2_k127_6773296_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 7.043e-260 815.0
CMS2_k127_6773296_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 524.0
CMS2_k127_6773296_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000004025 217.0
CMS2_k127_6780249_0 Acyl-CoA dehydrogenase type 2 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 518.0
CMS2_k127_6780249_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004747 246.0
CMS2_k127_6780249_2 Domain of unknown function DUF83 - - - 0.0000000000000000000000000000000001621 140.0
CMS2_k127_6786177_0 PFAM metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000002502 241.0
CMS2_k127_6789327_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 564.0
CMS2_k127_6789327_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000004445 240.0
CMS2_k127_6789327_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000009812 178.0
CMS2_k127_6789327_3 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000002444 106.0
CMS2_k127_6798573_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.021e-293 919.0
CMS2_k127_6798573_1 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 424.0
CMS2_k127_6798573_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006574 267.0
CMS2_k127_6798573_3 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000001458 183.0
CMS2_k127_6800656_0 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897,K02182,K05939 - 2.3.1.40,6.2.1.20,6.2.1.3,6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 395.0
CMS2_k127_6800656_1 lactate metabolic process - - - 0.00000000000000000000000000000000000000000000000000000000002056 222.0
CMS2_k127_6800656_2 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000038 176.0
CMS2_k127_6800656_3 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000001554 97.0
CMS2_k127_6800656_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000007152 59.0
CMS2_k127_6804100_0 Membrane - - - 0.0000000000000000000000000000000000000000000000000000002658 215.0
CMS2_k127_6808726_0 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 297.0
CMS2_k127_6808726_1 Succinyl-CoA 3-ketoacid-CoA transferase K01028 - 2.8.3.5 0.000000000000000000000000000000000000000000000000000000000002055 217.0
CMS2_k127_6808726_2 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000001316 206.0
CMS2_k127_6808726_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000007273 160.0
CMS2_k127_6808726_4 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000001143 148.0
CMS2_k127_6808726_5 Positive regulator of sigma-B K17763 - - 0.0000000001183 72.0
CMS2_k127_6808726_6 PAS fold - - - 0.00007896 53.0
CMS2_k127_6819283_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 294.0
CMS2_k127_6819283_1 Low-potential electron donor to a number of redox enzymes K03839 - - 0.0000000000000000000000000000000000000000000000009869 180.0
CMS2_k127_6819976_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 471.0
CMS2_k127_6819976_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K00001,K00008 - 1.1.1.1,1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 291.0
CMS2_k127_6819976_2 geranylgeranyl reductase activity K06444,K17830 - 1.3.1.101,1.3.7.11,5.5.1.18 0.0000000000000000000000000000000000000000000000000000007593 207.0
CMS2_k127_6819976_3 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000002584 132.0
CMS2_k127_6822378_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.769e-211 677.0
CMS2_k127_6822378_1 cheY-homologous receiver domain - - - 0.000000000000000000000000000000002694 132.0
CMS2_k127_6832882_0 Oxidoreductase family, NAD-binding Rossmann fold K18855 - 1.1.1.374 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 313.0
CMS2_k127_6832882_1 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000001006 246.0
CMS2_k127_6858371_0 Bacterial dnaA protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 436.0
CMS2_k127_6858371_1 TIGRFAM primosome, DnaD subunit - - - 0.00000000000000000000000000004102 122.0
CMS2_k127_6858371_2 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000006704 110.0
CMS2_k127_6858949_0 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000000000000000000000000004593 141.0
CMS2_k127_6858949_1 - - - - 0.0000000000000009629 89.0
CMS2_k127_688994_0 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000008569 206.0
CMS2_k127_688994_1 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000009909 197.0
CMS2_k127_688994_2 Protein of unknown function (DUF1616) - - - 0.000000000000000000000000000000000000003229 162.0
CMS2_k127_688994_3 Membrane-bound metal-dependent hydrolase - - - 0.000000000000000000000000002339 120.0
CMS2_k127_688994_4 PFAM Bacterial Ig-like domain (group 2) - - - 0.000000000000000000000000004375 121.0
CMS2_k127_688994_5 gluconolactonase activity - - - 0.000000000000000001797 100.0
CMS2_k127_688994_6 Polysaccharide biosynthesis protein - - - 0.000000000000001597 81.0
CMS2_k127_6899994_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 423.0
CMS2_k127_6899994_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 339.0
CMS2_k127_6899994_2 CoA-transferase family III K07543 - 2.8.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000078 282.0
CMS2_k127_6899994_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000001694 195.0
CMS2_k127_69093_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 3.692e-237 760.0
CMS2_k127_69093_1 PFAM glycosyl transferase family 2 K14597 - - 0.00000000000000000000000000000000000000000000000000000000000002541 229.0
CMS2_k127_69093_2 NYN domain - - - 0.00000000000000000000000000000000000009353 147.0
CMS2_k127_69093_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000002186 75.0
CMS2_k127_6911854_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000001104 127.0
CMS2_k127_6911854_1 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.00000000000000000000005831 109.0
CMS2_k127_692713_0 PFAM ATPase BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000002413 219.0
CMS2_k127_692713_1 PFAM ATPase BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000006147 179.0
CMS2_k127_692713_2 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000004819 173.0
CMS2_k127_6988127_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 363.0
CMS2_k127_6988127_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003402 244.0
CMS2_k127_6988127_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000002832 224.0
CMS2_k127_7044063_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006955 334.0
CMS2_k127_7044063_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000001288 183.0
CMS2_k127_7044063_3 - - - - 0.000000000000000000000000001026 120.0
CMS2_k127_7044063_4 Transport permease protein K01992,K18233 - - 0.0000000000000000000000007016 105.0
CMS2_k127_7044063_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000007233 63.0
CMS2_k127_7044063_6 - - - - 0.000000001723 62.0
CMS2_k127_7044601_0 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 329.0
CMS2_k127_7044601_1 Sir2 family K11416 - 2.4.2.31 0.000000000000000000000000000000000000000000000000004572 191.0
CMS2_k127_7044601_2 SnoaL-like domain - - - 0.0001006 46.0
CMS2_k127_70554_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000163 255.0
CMS2_k127_70554_1 Methylmuconolactone methyl-isomerase - - - 0.000000000000000002939 88.0
CMS2_k127_70554_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000001216 64.0
CMS2_k127_7078075_0 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000002562 256.0
CMS2_k127_7078075_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000004214 148.0
CMS2_k127_7078075_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000005284 124.0
CMS2_k127_7078075_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000001276 87.0
CMS2_k127_7084248_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 350.0
CMS2_k127_7084248_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008243 312.0
CMS2_k127_7084248_2 COG1062 Zn-dependent alcohol dehydrogenases, class III K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000003215 118.0
CMS2_k127_7084248_3 cobalamin binding - - - 0.00000001144 58.0
CMS2_k127_712044_0 AcrB/AcrD/AcrF family K03296 - - 1.989e-221 722.0
CMS2_k127_712044_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 587.0
CMS2_k127_712044_10 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000001914 168.0
CMS2_k127_712044_11 Bacterial Ig-like domain (group 1) - - - 0.000000000000000000000000000001093 142.0
CMS2_k127_712044_12 helix_turn_helix, Lux Regulon K07694,K11618 - - 0.000000000000000000000000001238 122.0
CMS2_k127_712044_13 WD40 repeat, subgroup - - - 0.000000000000000000000000007369 130.0
CMS2_k127_712044_14 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656 - 2.3.1.54 0.000000000000000000001078 95.0
CMS2_k127_712044_15 PFAM Class I peptide chain release factor K15034 - - 0.000000000000000005611 88.0
CMS2_k127_712044_16 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000000245 95.0
CMS2_k127_712044_17 helix_turn_helix multiple antibiotic resistance protein - - - 0.0003485 46.0
CMS2_k127_712044_2 molybdopterin cofactor binding K00183 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 500.0
CMS2_k127_712044_3 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K15022 - 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 430.0
CMS2_k127_712044_4 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 387.0
CMS2_k127_712044_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009063 346.0
CMS2_k127_712044_6 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000009187 238.0
CMS2_k127_712044_7 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000001193 219.0
CMS2_k127_712044_8 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000001455 220.0
CMS2_k127_712044_9 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000054 205.0
CMS2_k127_719312_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.21e-216 683.0
CMS2_k127_719312_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 492.0
CMS2_k127_732574_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 342.0
CMS2_k127_732574_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 325.0
CMS2_k127_732574_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 323.0
CMS2_k127_732574_3 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000003252 113.0
CMS2_k127_732574_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000546 102.0
CMS2_k127_749087_0 NADH flavin oxidoreductase NADH oxidase - - - 6.662e-194 625.0
CMS2_k127_749087_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 609.0
CMS2_k127_749087_2 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 424.0
CMS2_k127_749087_3 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000007557 201.0
CMS2_k127_749087_4 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000001742 166.0
CMS2_k127_749087_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000005266 161.0
CMS2_k127_749087_6 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000006137 132.0
CMS2_k127_749087_7 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.0000000000000000000000127 111.0
CMS2_k127_749087_8 - - - - 0.00000000000000000000001704 109.0
CMS2_k127_788818_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000004374 259.0
CMS2_k127_799816_0 60Kd inner membrane protein K03217 - - 0.0000000000000000000000000000000000000000000000000000000009413 213.0
CMS2_k127_799816_1 KH domain K06346 - - 0.00000000000000000000000000000000000000000002736 173.0
CMS2_k127_799816_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000001199 133.0
CMS2_k127_801587_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 1.962e-267 846.0
CMS2_k127_801587_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 511.0
CMS2_k127_801587_2 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000001357 64.0
CMS2_k127_818176_0 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 484.0
CMS2_k127_818176_1 PFAM alpha beta hydrolase fold K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000004085 248.0
CMS2_k127_818176_2 Prolipoprotein diacylglyceryl transferase - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00003714 49.0
CMS2_k127_832789_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000005696 131.0
CMS2_k127_84420_0 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 332.0
CMS2_k127_84420_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001597 241.0
CMS2_k127_84655_0 Domain of unknown function DUF11 - - - 0.0000000000000000000001342 110.0
CMS2_k127_856608_0 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 456.0
CMS2_k127_856608_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000001451 255.0
CMS2_k127_856608_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000001238 209.0
CMS2_k127_856608_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000002849 130.0
CMS2_k127_856608_4 SNARE associated Golgi protein - - - 0.000000002074 66.0
CMS2_k127_89600_0 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 304.0
CMS2_k127_89600_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005183 279.0
CMS2_k127_89600_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008683 253.0
CMS2_k127_89600_3 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006232 249.0
CMS2_k127_929663_0 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 9.897e-208 662.0
CMS2_k127_929663_1 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 386.0
CMS2_k127_940451_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.565e-272 857.0
CMS2_k127_940451_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000006222 237.0
CMS2_k127_960086_0 Conserved repeat domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004466 259.0
CMS2_k127_960086_1 Leucine Rich repeats (2 copies) - - - 0.000000000000000000000000000001243 140.0
CMS2_k127_960086_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.0006696 53.0
CMS2_k127_964931_0 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 621.0
CMS2_k127_964931_1 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000001775 132.0
CMS2_k127_964931_2 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.000000000000000996 83.0
CMS2_k127_975594_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000001969 136.0
CMS2_k127_975594_1 GPR1/FUN34/yaaH family K07034 - - 0.00000000000000000000000001222 113.0
CMS2_k127_975594_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000002016 113.0
CMS2_k127_97718_0 TIGRFAM molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 293.0
CMS2_k127_97718_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000002632 202.0
CMS2_k127_97718_2 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000489 155.0
CMS2_k127_992703_0 CoA-transferase family III K07544 - 2.8.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 338.0
CMS2_k127_992703_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 299.0
CMS2_k127_992703_2 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000002879 199.0