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Overview

ID MAG00437
Name CMS2_bin.49
Sample SMP0011
Taxonomy
Kingdom Bacteria
Phylum Campylobacterota
Class Campylobacteria
Order Campylobacterales
Family Sulfurimonadaceae
Genus JBFEYF01
Species
Assembly information
Completeness (%) 76.35
Contamination (%) 1.0
GC content (%) 44.0
N50 (bp) 10,707
Genome size (bp) 1,855,133

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1748

Gene name Description KEGG GOs EC E-value Score Sequence
CMS2_k127_1002887_0 MiaB-like tRNA modifying enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 580.0
CMS2_k127_1002887_1 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 508.0
CMS2_k127_1002887_10 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000003903 115.0
CMS2_k127_1002887_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 479.0
CMS2_k127_1002887_3 growth of symbiont in host cell K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 496.0
CMS2_k127_1002887_4 Belongs to the AAA ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009337 456.0
CMS2_k127_1002887_5 Probable molybdopterin binding domain K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 304.0
CMS2_k127_1002887_6 domain protein K09944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 287.0
CMS2_k127_1002887_7 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000008046 215.0
CMS2_k127_1002887_8 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000109 179.0
CMS2_k127_1002887_9 Domain of unknown function DUF302 - - - 0.00000000000000000000000000256 115.0
CMS2_k127_1091890_0 GGDEF domain - GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 370.0
CMS2_k127_1091890_1 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005646 243.0
CMS2_k127_1091890_2 PFAM response regulator receiver K03413 - - 0.0001312 50.0
CMS2_k127_1097290_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.683e-310 958.0
CMS2_k127_1097290_1 GTP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 609.0
CMS2_k127_1097290_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000006878 244.0
CMS2_k127_1097290_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000002299 154.0
CMS2_k127_1097290_4 Dynamin family - - - 0.000000000000000000001521 102.0
CMS2_k127_1108756_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1183.0
CMS2_k127_1108756_1 hydrogenase (NiFe) small subunit HydA K05927 - 1.12.5.1 0.0 1107.0
CMS2_k127_1108756_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 - 1.12.5.1 7.284e-299 923.0
CMS2_k127_1108756_3 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.141e-263 831.0
CMS2_k127_1108756_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K14091 - 1.6.5.3 0.00000000000000000000000000000000000000000000001606 174.0
CMS2_k127_1119456_0 ABC transporter K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 615.0
CMS2_k127_1119456_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 587.0
CMS2_k127_1119456_2 Mur ligase middle domain K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 575.0
CMS2_k127_1119456_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 469.0
CMS2_k127_1119456_4 Flagellar Assembly Protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 429.0
CMS2_k127_1119456_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 381.0
CMS2_k127_1119456_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 367.0
CMS2_k127_1119456_7 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 287.0
CMS2_k127_1119456_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000009171 229.0
CMS2_k127_1119456_9 S4 domain K14761 - - 0.0000000000000000000000005766 105.0
CMS2_k127_1130670_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.799e-242 754.0
CMS2_k127_1130670_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 588.0
CMS2_k127_1130670_10 K -dependent Na Ca exchanger K07301 - - 0.0000000000009751 69.0
CMS2_k127_1130670_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 404.0
CMS2_k127_1130670_3 potassium channel protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 403.0
CMS2_k127_1130670_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 299.0
CMS2_k127_1130670_5 ABC transporter, ATP-binding protein K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005422 242.0
CMS2_k127_1130670_6 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000002854 158.0
CMS2_k127_1130670_7 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.0000000000000000000000000000000000000004045 154.0
CMS2_k127_1130670_8 TrkA-N domain K10716 - - 0.00000000000000000000000000000000181 138.0
CMS2_k127_1130670_9 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000166 78.0
CMS2_k127_1164844_0 Potassium channel protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 515.0
CMS2_k127_1164844_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 494.0
CMS2_k127_1164844_2 HDOD domain - - - 0.0000000000000000000000000000007996 124.0
CMS2_k127_1164844_3 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000001242 102.0
CMS2_k127_1164844_4 Sodium:dicarboxylate symporter family - - - 0.0000000000000002207 85.0
CMS2_k127_117569_0 Flagellar hook protein flgE K02390 GO:0005575,GO:0005623,GO:0009288,GO:0009425,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464 - 1.694e-208 669.0
CMS2_k127_117569_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0005488,GO:0010181,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0097159,GO:0097367,GO:1901265,GO:1901363 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 556.0
CMS2_k127_117569_10 protein conserved in bacteria - - - 0.000000000000000000002944 94.0
CMS2_k127_117569_11 Belongs to the 'phage' integrase family - - - 0.000000009896 60.0
CMS2_k127_117569_2 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 509.0
CMS2_k127_117569_3 Two-component sensor histidine kinase response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006742 520.0
CMS2_k127_117569_4 pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 488.0
CMS2_k127_117569_5 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 435.0
CMS2_k127_117569_6 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 319.0
CMS2_k127_117569_7 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000002174 235.0
CMS2_k127_117569_8 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000543 176.0
CMS2_k127_117569_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000001047 107.0
CMS2_k127_1177249_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.257e-289 902.0
CMS2_k127_1177249_1 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 1.659e-224 715.0
CMS2_k127_1177249_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 481.0
CMS2_k127_1177249_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 391.0
CMS2_k127_1177249_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000008759 257.0
CMS2_k127_1191347_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 558.0
CMS2_k127_1191347_1 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 394.0
CMS2_k127_1191347_2 4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 381.0
CMS2_k127_1191347_3 COG5285 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin K00477 - 1.14.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 301.0
CMS2_k127_1191347_4 - - - - 0.000000000000000000000000000000000000000000000000000000000001611 213.0
CMS2_k127_1191347_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000007308 174.0
CMS2_k127_1191347_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000003818 154.0
CMS2_k127_1191347_7 Endonuclease I K01150 - 3.1.21.1 0.000000000000000000000000442 112.0
CMS2_k127_1191347_8 - - - - 0.00000000000000005546 87.0
CMS2_k127_1248669_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 2.02e-197 635.0
CMS2_k127_1248669_1 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 457.0
CMS2_k127_1248669_2 Guanosine pentaphosphate phosphohydrolase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 412.0
CMS2_k127_1248669_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000003022 263.0
CMS2_k127_1248669_5 Ferredoxin K05337 - - 0.0000000000000000000000000000000000000002269 150.0
CMS2_k127_1248669_6 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000003067 111.0
CMS2_k127_1282350_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1268.0
CMS2_k127_1282350_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 472.0
CMS2_k127_1282350_10 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000000000000000004537 137.0
CMS2_k127_1282350_11 Putative tRNA binding domain K06878 - - 0.000000000000000000000000000000000009951 137.0
CMS2_k127_1282350_12 Protein of unknown function, DUF255 - - - 0.00000000000000000002759 95.0
CMS2_k127_1282350_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 467.0
CMS2_k127_1282350_3 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 468.0
CMS2_k127_1282350_4 RNA pseudouridylate synthase K06175 - 5.4.99.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009691 328.0
CMS2_k127_1282350_5 Belongs to the DNA mismatch repair MutS family K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006284 269.0
CMS2_k127_1282350_6 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003844 265.0
CMS2_k127_1282350_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000005626 231.0
CMS2_k127_1282350_8 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000004144 181.0
CMS2_k127_1282350_9 endonuclease activity - - - 0.00000000000000000000000000000000000000000000001102 172.0
CMS2_k127_128485_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 490.0
CMS2_k127_128485_1 Cytochrome c oxidase accessory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 447.0
CMS2_k127_128485_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 304.0
CMS2_k127_1293755_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 2.794e-245 760.0
CMS2_k127_1293755_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 1.458e-227 715.0
CMS2_k127_1293755_10 Domain of unknown function (DUF1882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 307.0
CMS2_k127_1293755_11 chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 299.0
CMS2_k127_1293755_12 PFAM Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000005693 228.0
CMS2_k127_1293755_13 Belongs to the Fur family K03711 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000002337 205.0
CMS2_k127_1293755_14 morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.0000000000000000000000000000000000000000000000000000005422 211.0
CMS2_k127_1293755_15 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000001336 196.0
CMS2_k127_1293755_16 lytic transglycosylase activity - - - 0.00000000000000000000000000000000000000000000003487 175.0
CMS2_k127_1293755_17 Colicin V production protein K03558 - - 0.00000000000000000000000000000000000000000000004096 177.0
CMS2_k127_1293755_18 Cytochrome c - - - 0.0000000000000000000000000000000000000003374 153.0
CMS2_k127_1293755_19 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) K13694,K13695 - 3.4.17.13 0.0000000000000000000000000000000000000009008 154.0
CMS2_k127_1293755_2 anthranilate synthase component K01657 - 4.1.3.27 3.901e-202 639.0
CMS2_k127_1293755_20 PAS domain K03776 - - 0.000000000000000000000000000000000000003759 151.0
CMS2_k127_1293755_21 flagellar protein FliS K02422 - - 0.000000000000000000000000000000000004064 140.0
CMS2_k127_1293755_22 Cell division protein K03591,K03749 - - 0.000000000000000000000000003506 120.0
CMS2_k127_1293755_23 Chorismate mutase K04782 - 4.2.99.21 0.000000000000000000000000003539 113.0
CMS2_k127_1293755_25 FlaG protein K06603 - - 0.000000000000005081 79.0
CMS2_k127_1293755_26 - - - - 0.000008844 51.0
CMS2_k127_1293755_27 - - - - 0.00002388 49.0
CMS2_k127_1293755_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 512.0
CMS2_k127_1293755_4 chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 468.0
CMS2_k127_1293755_5 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 450.0
CMS2_k127_1293755_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 381.0
CMS2_k127_1293755_7 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 376.0
CMS2_k127_1293755_8 na -driven multidrug efflux - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 361.0
CMS2_k127_1293755_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 343.0
CMS2_k127_1309923_0 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 364.0
CMS2_k127_1309923_1 NUDIX domain K16855 - 3.6.1.62,3.6.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 302.0
CMS2_k127_1309923_3 PFAM Thioredoxin domain K03671 - - 0.00003666 47.0
CMS2_k127_1355330_0 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006006 268.0
CMS2_k127_1355330_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000002857 198.0
CMS2_k127_1373497_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 4.771e-307 946.0
CMS2_k127_1373497_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 8.953e-242 760.0
CMS2_k127_1373497_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 520.0
CMS2_k127_1373497_3 outer membrane porin, OprD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005968 406.0
CMS2_k127_1373497_4 dna polymerase iii K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 294.0
CMS2_k127_1373497_5 membrane - - - 0.00000000000000000000000000000000000000002291 154.0
CMS2_k127_1373497_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000002601 61.0
CMS2_k127_1373539_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 5.409e-206 654.0
CMS2_k127_1373539_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 438.0
CMS2_k127_1373539_2 Phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.000000000000000009447 92.0
CMS2_k127_1373539_3 Protein of unknown function, DUF485 - - - 0.0000000000005289 72.0
CMS2_k127_1394990_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 460.0
CMS2_k127_1394990_1 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 428.0
CMS2_k127_1394990_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 334.0
CMS2_k127_1395032_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.385e-281 872.0
CMS2_k127_1395032_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 3.499e-269 845.0
CMS2_k127_1395032_10 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000000000000000000000000000000000000000000000005183 212.0
CMS2_k127_1395032_11 Low molecular weight phosphotyrosine protein phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000006698 198.0
CMS2_k127_1395032_12 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000936 201.0
CMS2_k127_1395032_13 Thioredoxin K07396 - - 0.000000000000000000000000000000000000000000000000001057 189.0
CMS2_k127_1395032_14 Bacterial periplasmic substrate-binding proteins - - - 0.0000000000000000000000000000000000000000000005932 184.0
CMS2_k127_1395032_15 - - - - 0.00000000000000000000000000000000004148 145.0
CMS2_k127_1395032_16 Flagellar hook-length control protein FliK - - - 0.00000000000000000000000000003168 134.0
CMS2_k127_1395032_17 Preprotein translocase subunit SecG K03075 - - 0.0000000000000000000003473 102.0
CMS2_k127_1395032_18 peptide-methionine (S)-S-oxide reductase activity - - - 0.000000000000000000009296 95.0
CMS2_k127_1395032_19 biotin synthesis protein bioC K02169 - 2.1.1.197 0.000000000000003414 79.0
CMS2_k127_1395032_2 Single-stranded-DNA-specific exonuclease (RecJ) K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 599.0
CMS2_k127_1395032_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 345.0
CMS2_k127_1395032_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 319.0
CMS2_k127_1395032_5 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 305.0
CMS2_k127_1395032_6 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 300.0
CMS2_k127_1395032_7 Abc transporter K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007025 280.0
CMS2_k127_1395032_8 Flagellar basal body protein K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003369 282.0
CMS2_k127_1395032_9 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003986 241.0
CMS2_k127_1403102_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1153.0
CMS2_k127_1403102_1 Histidine kinase - - - 1.833e-312 988.0
CMS2_k127_1403102_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 6.868e-208 663.0
CMS2_k127_1403102_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000003558 231.0
CMS2_k127_1403102_4 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K03776 - - 0.0000000000000000000000000000000000000000000000000000007993 195.0
CMS2_k127_1403102_5 Response regulator receiver K07814 - - 0.0000000000000000000000000000000001629 136.0
CMS2_k127_1403102_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000002559 85.0
CMS2_k127_1409950_0 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002834 237.0
CMS2_k127_1409950_1 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000000000000000000000002849 213.0
CMS2_k127_1409950_2 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000001385 145.0
CMS2_k127_1409950_3 Cytochrome c family protein - - - 0.00000000000000000000000000000000001714 143.0
CMS2_k127_1409950_4 Possible plasma membrane-binding motif in junctophilins, PIP-5-kinases and protein kinases. - - - 0.00000003365 66.0
CMS2_k127_1523489_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 574.0
CMS2_k127_1523489_1 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 530.0
CMS2_k127_1523489_10 Methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000109 212.0
CMS2_k127_1523489_11 Serine hydrolase K07002 - - 0.0000000000000000000001316 104.0
CMS2_k127_1523489_12 Lipid A 3-O-deacylase (PagL) K12976 - - 0.00000000000000000004094 94.0
CMS2_k127_1523489_13 - - - - 0.000000008137 60.0
CMS2_k127_1523489_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 450.0
CMS2_k127_1523489_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 437.0
CMS2_k127_1523489_4 chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 428.0
CMS2_k127_1523489_5 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 337.0
CMS2_k127_1523489_6 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 338.0
CMS2_k127_1523489_7 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 286.0
CMS2_k127_1523489_8 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009419 255.0
CMS2_k127_1523489_9 Histidine kinase K13040 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000003863 259.0
CMS2_k127_1531467_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 472.0
CMS2_k127_1531467_1 COG1393 Arsenate reductase and related K00537 - 1.20.4.1 0.00000000000000000000000000000002058 129.0
CMS2_k127_1537714_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 1.264e-210 661.0
CMS2_k127_1537714_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 471.0
CMS2_k127_1537714_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 360.0
CMS2_k127_1537714_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 302.0
CMS2_k127_1537714_4 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000007952 250.0
CMS2_k127_1542880_0 Sensors of blue-light using FAD - - - 0.0 1111.0
CMS2_k127_1542880_1 phosphate transport system permease protein K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 572.0
CMS2_k127_1542880_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 424.0
CMS2_k127_1542880_3 flavin adenine dinucleotide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 382.0
CMS2_k127_1542880_4 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 367.0
CMS2_k127_1542880_5 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.00000000000000000000000000000000000000000000003067 170.0
CMS2_k127_1542880_6 PhoU family K02039 - - 0.0000000000000000000000000000001427 132.0
CMS2_k127_1542880_7 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.000000000000000000000000004223 112.0
CMS2_k127_1542880_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000005289 111.0
CMS2_k127_1542880_9 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000004449 60.0
CMS2_k127_1648229_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 501.0
CMS2_k127_1648229_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 320.0
CMS2_k127_1648229_2 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006912 311.0
CMS2_k127_1648229_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000003305 115.0
CMS2_k127_1672272_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 2.764e-196 631.0
CMS2_k127_1672272_1 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001929 243.0
CMS2_k127_1672272_2 ABC transporter K02003 - - 0.000000000000000000000122 100.0
CMS2_k127_1678190_0 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 290.0
CMS2_k127_1678190_1 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000002084 232.0
CMS2_k127_1678190_2 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000007383 216.0
CMS2_k127_1678190_3 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000003232 199.0
CMS2_k127_1678190_4 dna polymerase iii K10857 - - 0.0000000000000000000000000000000000000000000000001095 185.0
CMS2_k127_1678190_5 - - - - 0.0000000000000000000000000000000003343 135.0
CMS2_k127_1678190_6 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000769 104.0
CMS2_k127_1678190_7 Prokaryotic metallothionein K06950 - - 0.000000003511 60.0
CMS2_k127_1798515_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 3.269e-234 734.0
CMS2_k127_1798515_1 COGs COG2829 Outer membrane phospholipase A K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 295.0
CMS2_k127_1798515_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000003217 251.0
CMS2_k127_1798515_3 RESPONSE REGULATOR receiver K07288 - - 0.0000000000000000000000000000000000000000000007974 186.0
CMS2_k127_1798515_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000006171 88.0
CMS2_k127_1798515_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000006045 76.0
CMS2_k127_1819723_0 threonine synthase K01733 - 4.2.3.1 2.035e-233 730.0
CMS2_k127_1819723_1 Co-chaperone-curved DNA binding protein A K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 381.0
CMS2_k127_1819723_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 346.0
CMS2_k127_1819723_3 Transcriptional regulator K13640 - - 0.0000000000000000000000000000000000000000000001588 170.0
CMS2_k127_1819723_4 cheY-homologous receiver domain - - - 0.000000000000000000000000006398 121.0
CMS2_k127_1819723_5 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000343 53.0
CMS2_k127_1882699_0 Histidine kinase K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 621.0
CMS2_k127_1882699_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 346.0
CMS2_k127_1882699_2 Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division K08306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 311.0
CMS2_k127_1882699_3 - K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000000000006222 192.0
CMS2_k127_1882699_4 SCO1/SenC K07152 - - 0.000000000000000000000546 102.0
CMS2_k127_1882699_5 Rubredoxin - - - 0.00000000000000000008496 91.0
CMS2_k127_1926440_0 GHKL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 432.0
CMS2_k127_1926440_1 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 362.0
CMS2_k127_1926440_10 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000008321 134.0
CMS2_k127_1926440_11 cheY-homologous receiver domain - - - 0.000000000000000000000000000000004072 144.0
CMS2_k127_1926440_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 348.0
CMS2_k127_1926440_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 310.0
CMS2_k127_1926440_4 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001955 284.0
CMS2_k127_1926440_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002259 267.0
CMS2_k127_1926440_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000008252 246.0
CMS2_k127_1926440_7 COGs COG1776 Chemotaxis protein CheC inhibitor of MCP methylation K03410 - - 0.00000000000000000000000000000000000000000000000000003528 194.0
CMS2_k127_1926440_8 response regulator, receiver K00384,K07315 - 1.8.1.9,3.1.3.3 0.00000000000000000000000000000000000000000001224 175.0
CMS2_k127_1926440_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000003421 146.0
CMS2_k127_1975193_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.129e-306 951.0
CMS2_k127_1975193_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 7.186e-276 860.0
CMS2_k127_1975193_2 7TMR-DISM extracellular 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 611.0
CMS2_k127_1975193_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 479.0
CMS2_k127_1975193_4 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 471.0
CMS2_k127_1975193_5 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 355.0
CMS2_k127_1975193_6 Pfam:Cache_2 - - - 0.000000000000000000000000004178 124.0
CMS2_k127_1975193_7 - - - - 0.0000000000000000003871 93.0
CMS2_k127_1975193_8 - - - - 0.00003284 48.0
CMS2_k127_1988357_0 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.00000000000000000000000000000000000000000000000000000000000002787 222.0
CMS2_k127_1988357_1 PFAM glutaredoxin - - - 0.000000000000000000000000000000000000001916 156.0
CMS2_k127_1988357_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000006406 124.0
CMS2_k127_1988357_3 COG1734 DnaK suppressor protein K06204 - - 0.00000000000000006632 84.0
CMS2_k127_1988357_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.0000000003479 67.0
CMS2_k127_2020174_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 442.0
CMS2_k127_2020174_1 DnaJ domain protein K05801 - - 0.0000000000000000000000000000000000000000000002997 176.0
CMS2_k127_2020174_2 Response regulator receiver K03415 - - 0.000000000000000000000000000000000000000001107 159.0
CMS2_k127_2020174_3 PFAM FecR protein - - - 0.0000000000000000000000000008242 126.0
CMS2_k127_2054396_0 argininosuccinate lyase K01755 - 4.3.2.1 2.388e-221 694.0
CMS2_k127_2054396_1 Belongs to the TtcA family K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 348.0
CMS2_k127_2054396_2 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K18284 - 3.2.2.30,3.2.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 331.0
CMS2_k127_2054396_3 malonyl coa-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 331.0
CMS2_k127_2054396_4 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009122 267.0
CMS2_k127_2054396_5 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003579 240.0
CMS2_k127_2054396_6 5'-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000003237 171.0
CMS2_k127_2085644_0 stage II sporulation protein E - - - 0.00000000000000000000000000000000000000000000000000008239 212.0
CMS2_k127_2085644_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000001172 173.0
CMS2_k127_2085644_2 Domain of unknown function (DUF1987) - - - 0.0000000000000000000000000002232 118.0
CMS2_k127_2085644_3 Diguanylate cyclase - - - 0.000000000000000000000000003754 129.0
CMS2_k127_2085644_4 Uncharacterised ACR, YagE family COG1723 - - - 0.00000002672 55.0
CMS2_k127_2088750_0 abc transporter atp-binding protein - - - 5.698e-274 848.0
CMS2_k127_2088750_1 alanine dehydrogenase K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 433.0
CMS2_k127_2088750_11 mismatched DNA binding K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000001192 93.0
CMS2_k127_2088750_12 Translation initiation factor SUI1 K03113 - - 0.0000000000000001474 84.0
CMS2_k127_2088750_2 molybdopterin biosynthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 413.0
CMS2_k127_2088750_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006262 388.0
CMS2_k127_2088750_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 300.0
CMS2_k127_2088750_5 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005716 277.0
CMS2_k127_2088750_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000003624 215.0
CMS2_k127_2088750_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000168 197.0
CMS2_k127_2088750_8 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000001367 118.0
CMS2_k127_2088750_9 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000305 111.0
CMS2_k127_2148925_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000716 510.0
CMS2_k127_2148925_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 396.0
CMS2_k127_2148925_2 Pseudouridine synthase K06177,K06179,K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 316.0
CMS2_k127_2148925_3 WD40 repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000255 224.0
CMS2_k127_2148925_4 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000000000000000000000004072 201.0
CMS2_k127_2148925_5 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000005951 188.0
CMS2_k127_2148925_6 signal transduction sensor histidine kinase - - - 0.000000000000000000000000000004871 124.0
CMS2_k127_2148925_7 Ankyrin repeats (3 copies) - - - 0.00000000000000000002244 97.0
CMS2_k127_2237058_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.312e-260 816.0
CMS2_k127_2237058_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 3.205e-220 686.0
CMS2_k127_2237058_10 - - - - 0.0000000000001992 77.0
CMS2_k127_2237058_2 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 589.0
CMS2_k127_2237058_3 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 312.0
CMS2_k127_2237058_4 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000002878 236.0
CMS2_k127_2237058_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000003804 203.0
CMS2_k127_2237058_6 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000000000000000002059 135.0
CMS2_k127_2237058_7 Family of unknown function (DUF695) - - - 0.0000000000000000000000008451 113.0
CMS2_k127_2237058_8 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000000000000008514 98.0
CMS2_k127_2237058_9 cheY-homologous receiver domain K03413 - - 0.00000000000000000001469 96.0
CMS2_k127_2356653_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 527.0
CMS2_k127_2356653_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 437.0
CMS2_k127_2356653_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005938 362.0
CMS2_k127_2356653_3 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000002379 76.0
CMS2_k127_2432382_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.271e-201 637.0
CMS2_k127_2432382_1 COG0841 Cation multidrug efflux pump - - - 1.177e-198 633.0
CMS2_k127_2432382_10 Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell K03608 - - 0.0000000000000000000001166 100.0
CMS2_k127_2432382_11 DNA processing protein K04096 - - 0.0000000000000000000003629 100.0
CMS2_k127_2432382_12 Putative bacterial sensory transduction regulator - - - 0.00004392 51.0
CMS2_k127_2432382_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 450.0
CMS2_k127_2432382_3 Belongs to the ParA family K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 399.0
CMS2_k127_2432382_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 350.0
CMS2_k127_2432382_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 336.0
CMS2_k127_2432382_6 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000000000000000001851 215.0
CMS2_k127_2432382_7 DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000001435 130.0
CMS2_k127_2432382_8 phosphorelay signal transduction system - - - 0.00000000000000000000000000000008613 130.0
CMS2_k127_2432382_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000001702 111.0
CMS2_k127_2454143_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 489.0
CMS2_k127_2454143_1 Cytochrome K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 461.0
CMS2_k127_2454143_10 S4 domain protein - - - 0.000000000000000000000000000003839 120.0
CMS2_k127_2454143_11 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000001731 111.0
CMS2_k127_2454143_12 YtkA-like - - - 0.0000000000000000000000000761 111.0
CMS2_k127_2454143_13 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.00000000000000000000406 100.0
CMS2_k127_2454143_14 Histidine kinase K07645 - 2.7.13.3 0.000000000000000274 89.0
CMS2_k127_2454143_2 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 387.0
CMS2_k127_2454143_3 ABC transporter, ATP-binding protein K01990,K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 374.0
CMS2_k127_2454143_4 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 377.0
CMS2_k127_2454143_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 330.0
CMS2_k127_2454143_6 tigr02757 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 300.0
CMS2_k127_2454143_7 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005055 283.0
CMS2_k127_2454143_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000007088 194.0
CMS2_k127_2454143_9 ATPase or kinase K06925 - - 0.000000000000000000000000000000000002414 142.0
CMS2_k127_2456406_0 Highly conserved protein containing a thioredoxin domain K06888 - - 3.069e-194 622.0
CMS2_k127_2456406_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 373.0
CMS2_k127_2456406_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 361.0
CMS2_k127_2456406_3 ABC transporter, ATP-binding protein K02003 - - 0.0000000000000000000000000000000000000000001814 162.0
CMS2_k127_2456406_4 Histidine kinase K13040 - 2.7.13.3 0.00000000000000000000000000000000000000002449 171.0
CMS2_k127_2456406_5 Protein of unknown function (DUF3299) - - - 0.000000000000000000000000006653 117.0
CMS2_k127_2458611_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 432.0
CMS2_k127_2458611_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000008726 235.0
CMS2_k127_2458611_2 DnaK suppressor protein K06204 - - 0.0000000000000000000000000000000000000001254 153.0
CMS2_k127_2458611_3 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000005295 131.0
CMS2_k127_2458611_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000001308 76.0
CMS2_k127_2468810_0 Belongs to the ClpA ClpB family K03694,K03695 - - 0.0 1197.0
CMS2_k127_2468810_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 533.0
CMS2_k127_2468810_2 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 407.0
CMS2_k127_2468810_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 354.0
CMS2_k127_2468810_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000002442 227.0
CMS2_k127_2468810_5 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - GO:0000156,GO:0000160,GO:0003674,GO:0003824,GO:0004112,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008081,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009187,GO:0009214,GO:0009987,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0023052,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035556,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055086,GO:0060089,GO:0065007,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.000000000000000000000000000000000257 135.0
CMS2_k127_2468810_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000006179 111.0
CMS2_k127_2536279_0 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 596.0
CMS2_k127_2536279_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 513.0
CMS2_k127_2536279_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 417.0
CMS2_k127_2536279_3 dehydrogenase K00076 - 1.1.1.159 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 403.0
CMS2_k127_2536279_4 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 372.0
CMS2_k127_2536279_5 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0048033,GO:0048034,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 333.0
CMS2_k127_2536279_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 333.0
CMS2_k127_2536279_7 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005036 278.0
CMS2_k127_2536279_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000006783 238.0
CMS2_k127_2536279_9 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000002663 121.0
CMS2_k127_2563060_0 Acts as a magnesium transporter K06213 - - 7.153e-227 709.0
CMS2_k127_2563060_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 297.0
CMS2_k127_2563060_2 Uncharacterised ACR, YagE family COG1723 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000017 276.0
CMS2_k127_2563060_3 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000000000000000000000002176 218.0
CMS2_k127_2563060_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000000000000000001375 160.0
CMS2_k127_2619393_0 COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase K15022 - 1.17.1.10 0.0 1142.0
CMS2_k127_2619393_1 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 1.181e-302 945.0
CMS2_k127_2619393_2 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 4.923e-211 662.0
CMS2_k127_2619393_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 583.0
CMS2_k127_2619393_4 putative NADH-ubiquinone oxidoreductase chain E K00334 - 1.6.5.3 0.000000000000000000000000000002536 121.0
CMS2_k127_2624800_0 Belongs to the HypD family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 558.0
CMS2_k127_2624800_1 hydrogenase expression formation protein K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 475.0
CMS2_k127_2624800_10 cheY-homologous receiver domain - - - 0.000000000000000000000000006856 122.0
CMS2_k127_2624800_2 Hydrogenase K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 419.0
CMS2_k127_2624800_3 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 364.0
CMS2_k127_2624800_4 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002336 273.0
CMS2_k127_2624800_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002642 276.0
CMS2_k127_2624800_6 hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000002795 181.0
CMS2_k127_2624800_7 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000000000001048 160.0
CMS2_k127_2624800_8 hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000005827 151.0
CMS2_k127_2624800_9 hydrogenase assembly chaperone HypC K04653 - - 0.00000000000000000000000000001116 119.0
CMS2_k127_2638196_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 542.0
CMS2_k127_2638196_1 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 404.0
CMS2_k127_2638196_10 cytoplasmic domain of flagellar protein FhlB K04061 - - 0.00000000000000000003166 92.0
CMS2_k127_2638196_11 - - - - 0.0000000000000001567 82.0
CMS2_k127_2638196_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 364.0
CMS2_k127_2638196_3 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 324.0
CMS2_k127_2638196_4 protein phosphatase 2C domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003815 297.0
CMS2_k127_2638196_5 riboflavin synthase alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002917 269.0
CMS2_k127_2638196_6 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003408 265.0
CMS2_k127_2638196_7 COG2346 Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000000000000000004935 205.0
CMS2_k127_2638196_8 Protein of unknown function (DUF2393) - - - 0.0000000000000000000000003986 111.0
CMS2_k127_2638196_9 Protein of unknown function (DUF2393) - - - 0.000000000000000000000004241 109.0
CMS2_k127_2675049_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1192.0
CMS2_k127_2675049_1 DNA helicase K03657 - 3.6.4.12 2.594e-267 839.0
CMS2_k127_2675049_10 COG0642 Signal transduction histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000001159 257.0
CMS2_k127_2675049_11 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000004717 218.0
CMS2_k127_2675049_12 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000007131 211.0
CMS2_k127_2675049_13 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000001895 192.0
CMS2_k127_2675049_14 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000001245 186.0
CMS2_k127_2675049_15 - - - - 0.00000000000000000000000000000000000000000000002946 171.0
CMS2_k127_2675049_16 - - - - 0.00000000000000000000000000000000000000001669 158.0
CMS2_k127_2675049_17 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.000000000000000000000000000000000001676 145.0
CMS2_k127_2675049_18 Stress responsive A B Barrel Domain - - - 0.000000000000000000000000000003885 122.0
CMS2_k127_2675049_19 Preprotein translocase K03210 - - 0.000000000000000000000006182 105.0
CMS2_k127_2675049_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 2.41e-216 683.0
CMS2_k127_2675049_20 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000009614 98.0
CMS2_k127_2675049_22 Lipopolysaccharide-assembly - - - 0.000000000000004677 78.0
CMS2_k127_2675049_24 Global regulator protein family - - - 0.000006464 51.0
CMS2_k127_2675049_3 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 489.0
CMS2_k127_2675049_4 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 471.0
CMS2_k127_2675049_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 439.0
CMS2_k127_2675049_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005773 416.0
CMS2_k127_2675049_7 apolipoprotein N-acyltransferase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 338.0
CMS2_k127_2675049_8 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 304.0
CMS2_k127_2675049_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000001516 261.0
CMS2_k127_2691398_0 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000002824 227.0
CMS2_k127_2691398_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000002292 206.0
CMS2_k127_2691398_2 Cytochrome c oxidase accessory protein - - - 0.000000000007843 67.0
CMS2_k127_2691970_0 Type I secretion system ATPase K12541 - - 6.288e-267 839.0
CMS2_k127_2691970_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 482.0
CMS2_k127_2691970_10 PFAM Cobinamide kinase cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000003299 173.0
CMS2_k127_2691970_11 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000005312 166.0
CMS2_k127_2691970_12 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000008173 126.0
CMS2_k127_2691970_13 S-layer homology domain - - - 0.000000000000000000000000138 125.0
CMS2_k127_2691970_14 chemotaxis K03406 - - 0.0000000000000000000000001567 113.0
CMS2_k127_2691970_15 Protein of unknown function (DUF1566) - - - 0.0000000000000000001363 105.0
CMS2_k127_2691970_16 - - - - 0.00000000000003214 82.0
CMS2_k127_2691970_17 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000002025 62.0
CMS2_k127_2691970_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 484.0
CMS2_k127_2691970_3 type I secretion membrane fusion protein, HlyD family K02022,K12542 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 438.0
CMS2_k127_2691970_4 phosphoribosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 376.0
CMS2_k127_2691970_5 Outer membrane efflux protein K12543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003338 269.0
CMS2_k127_2691970_6 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000000002714 234.0
CMS2_k127_2691970_7 Bacterial transglutaminase-like cysteine proteinase BTLCP - - - 0.00000000000000000000000000000000000000000000000000000001502 204.0
CMS2_k127_2691970_8 regulator of chromosome condensation, RCC1 K20276 - - 0.0000000000000000000000000000000000000000000000000005682 211.0
CMS2_k127_2691970_9 outer membrane porin, OprD family - - - 0.0000000000000000000000000000000000000000000002134 185.0
CMS2_k127_27021_0 FGGY family of carbohydrate kinases, N-terminal domain K11216 - 2.7.1.189 7.254e-228 715.0
CMS2_k127_27021_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 4.275e-194 614.0
CMS2_k127_27021_10 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004399 270.0
CMS2_k127_27021_11 Haemolysin-III related K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005772 271.0
CMS2_k127_27021_12 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001322 293.0
CMS2_k127_27021_13 WD40 repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006787 286.0
CMS2_k127_27021_14 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000001454 258.0
CMS2_k127_27021_15 membrane organization K20543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001948 262.0
CMS2_k127_27021_16 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001106 251.0
CMS2_k127_27021_17 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000005471 191.0
CMS2_k127_27021_18 Protein of unknown function (DUF2459) - - - 0.0000000000000000000000000000000000000000000000009065 181.0
CMS2_k127_27021_19 Protein of unknown function (DUF3972) - - - 0.000000000000000000000000000000000000000000000002516 177.0
CMS2_k127_27021_2 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 553.0
CMS2_k127_27021_20 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000003026 174.0
CMS2_k127_27021_21 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000003245 168.0
CMS2_k127_27021_22 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000000002037 138.0
CMS2_k127_27021_23 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000001004 122.0
CMS2_k127_27021_24 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000002342 119.0
CMS2_k127_27021_25 RNA-binding protein K06960 - - 0.0000000000000000000000008116 105.0
CMS2_k127_27021_26 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000000002814 93.0
CMS2_k127_27021_3 PFAM Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 499.0
CMS2_k127_27021_4 3-deoxy-d-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 395.0
CMS2_k127_27021_5 Metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 363.0
CMS2_k127_27021_6 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 301.0
CMS2_k127_27021_7 Belongs to the pseudouridine synthase RluA family K06179,K06180 - 5.4.99.23,5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 290.0
CMS2_k127_27021_8 dinuclear metal center protein, YbgI K22391 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001301 283.0
CMS2_k127_27021_9 COG1579 Zn-ribbon protein possibly nucleic acid-binding K07164,K22391 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006672 276.0
CMS2_k127_2718883_0 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 2.268e-295 914.0
CMS2_k127_2718883_1 Belongs to the DEAD box helicase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 566.0
CMS2_k127_2718883_2 Heterodisulfide reductase subunit B K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 491.0
CMS2_k127_2718883_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 471.0
CMS2_k127_2718883_4 membrane K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 379.0
CMS2_k127_2718883_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000001974 198.0
CMS2_k127_2718883_7 Diguanylate cyclase, GGDEF domain - - - 0.000000000000000000000000000000004139 143.0
CMS2_k127_2718883_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286,K12976,K16079 - - 0.0000003937 58.0
CMS2_k127_2762218_0 Alpha-2-Macroglobulin K06894 - - 8.027e-270 895.0
CMS2_k127_2762218_1 penicillin-binding protein K05367 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 597.0
CMS2_k127_2762218_10 Histidine kinase K03407 - 2.7.13.3 0.0000000000000000000000000000000001874 136.0
CMS2_k127_2762218_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000002134 118.0
CMS2_k127_2762218_12 - - - - 0.000000000007721 69.0
CMS2_k127_2762218_14 Cell shape determining protein MreB Mrl K03569 - - 0.000001475 55.0
CMS2_k127_2762218_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 478.0
CMS2_k127_2762218_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 361.0
CMS2_k127_2762218_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 359.0
CMS2_k127_2762218_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008027 339.0
CMS2_k127_2762218_6 acid membrane antigen A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 295.0
CMS2_k127_2762218_7 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009298 292.0
CMS2_k127_2762218_8 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001809 289.0
CMS2_k127_2762218_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000006163 192.0
CMS2_k127_2763824_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 3.329e-283 885.0
CMS2_k127_2763824_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 592.0
CMS2_k127_2763824_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 403.0
CMS2_k127_2763824_3 His Kinase A (phospho-acceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 363.0
CMS2_k127_2763824_4 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 316.0
CMS2_k127_2763824_5 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000006685 245.0
CMS2_k127_2763824_6 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000001009 209.0
CMS2_k127_2763824_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000265 145.0
CMS2_k127_2763824_8 Domain of unknown function (DUF4389) - - - 0.0000000000001062 75.0
CMS2_k127_2763824_9 Fe2 transport system protein A K04758 - - 0.0000001884 58.0
CMS2_k127_2814247_0 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000001048 246.0
CMS2_k127_2814247_1 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000002593 201.0
CMS2_k127_2814247_2 WD40 repeats - - - 0.0000000000000000000000000000000000000000000001525 184.0
CMS2_k127_2814247_3 Histidine kinase - - - 0.00000000000000000000000000000000000007183 153.0
CMS2_k127_2847584_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 469.0
CMS2_k127_2847584_1 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 451.0
CMS2_k127_2847584_2 PFAM phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000003532 258.0
CMS2_k127_2847584_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000002337 245.0
CMS2_k127_2847584_4 Diguanylate cyclase - - - 0.0000000000000000000000000004355 131.0
CMS2_k127_2847584_5 - - - - 0.00000007537 63.0
CMS2_k127_309785_0 transferase activity, transferring glycosyl groups K00754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 373.0
CMS2_k127_309785_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 341.0
CMS2_k127_309785_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 291.0
CMS2_k127_3132357_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1221.0
CMS2_k127_3132357_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 536.0
CMS2_k127_3132357_10 - - - - 0.0000355 51.0
CMS2_k127_3132357_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 531.0
CMS2_k127_3132357_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 518.0
CMS2_k127_3132357_4 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 320.0
CMS2_k127_3132357_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001298 286.0
CMS2_k127_3132357_6 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000003482 215.0
CMS2_k127_3132357_7 (Lipo)protein K09860 - - 0.00000000000000000000000000000008036 132.0
CMS2_k127_3132357_9 PAS domain - - - 0.0000001101 64.0
CMS2_k127_313941_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.241e-277 871.0
CMS2_k127_3183429_0 dehydrogenase K08325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 529.0
CMS2_k127_3183429_1 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 390.0
CMS2_k127_3183429_2 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 390.0
CMS2_k127_3183429_3 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 366.0
CMS2_k127_3183429_4 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 327.0
CMS2_k127_3183429_5 Transcriptional Regulator AraC Family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 309.0
CMS2_k127_3183429_6 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003525 237.0
CMS2_k127_3183429_7 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004083 236.0
CMS2_k127_3183429_8 CHASE3 domain - - - 0.0000000000000005396 86.0
CMS2_k127_3192016_0 Glycolate oxidase subunit K00104 - 1.1.3.15 1.143e-263 816.0
CMS2_k127_3192016_1 peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 387.0
CMS2_k127_3192016_2 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000002866 213.0
CMS2_k127_3192016_3 Competence protein K02238 - - 0.0000000000000000000000000000000000000003072 159.0
CMS2_k127_3192016_4 Plasminogen-binding protein pgbA N-terminal - - - 0.0000000000000000000000002303 114.0
CMS2_k127_3192016_5 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 0.000000000000000000002753 95.0
CMS2_k127_3192016_6 Acts as a magnesium transporter K06213 - - 0.0000006247 53.0
CMS2_k127_3313928_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1022.0
CMS2_k127_3313928_1 Aminotransferase K14261 - - 2.742e-206 647.0
CMS2_k127_3313928_10 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000006944 124.0
CMS2_k127_3313928_11 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000004236 115.0
CMS2_k127_3313928_2 homoserine dehydrogenase K00003 - 1.1.1.3 6.576e-194 612.0
CMS2_k127_3313928_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 485.0
CMS2_k127_3313928_4 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 400.0
CMS2_k127_3313928_5 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000848 258.0
CMS2_k127_3313928_6 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000002679 192.0
CMS2_k127_3313928_7 - - - - 0.000000000000000000000000000000000000000000000000000012 198.0
CMS2_k127_3313928_8 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000001555 162.0
CMS2_k127_3313928_9 - - - - 0.000000000000000000000000000000000000003815 150.0
CMS2_k127_3333474_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 466.0
CMS2_k127_3333474_1 PFAM Auxin Efflux Carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 303.0
CMS2_k127_3333474_2 anaerobic cobalamin biosynthetic process K02190 - 4.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 292.0
CMS2_k127_3333474_3 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 289.0
CMS2_k127_3333474_4 HDOD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002714 234.0
CMS2_k127_3333474_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000004482 197.0
CMS2_k127_3333474_6 Cobalt uptake substrate-specific transmembrane region - - - 0.000000000000000000000000000000000000000000000000001241 186.0
CMS2_k127_3333474_7 Mg chelatase-related protein K07391 - - 0.000000000000000000000000000004603 124.0
CMS2_k127_3333474_8 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000000000985 104.0
CMS2_k127_3333474_9 Tetratricopeptide repeat - - - 0.000000001102 68.0
CMS2_k127_3355671_0 Putative exonuclease SbcCD, C subunit K03546 - - 3.942e-286 919.0
CMS2_k127_3355671_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 518.0
CMS2_k127_3355671_2 Domain of unknown function (DUF4145) - - - 0.000000000000000000000000000000000000000000000000000000000000000003485 231.0
CMS2_k127_3397376_0 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 558.0
CMS2_k127_3397376_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000199 280.0
CMS2_k127_3397376_2 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.00000000000000000000000000000000000000000000000000000000000001715 226.0
CMS2_k127_3397376_3 Ankyrin repeat - - - 0.00000000000000000000000000000008956 130.0
CMS2_k127_3421719_0 Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 576.0
CMS2_k127_3421719_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 291.0
CMS2_k127_3421719_2 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000002506 129.0
CMS2_k127_3421719_3 - - - - 0.0000000000000000000000000001798 117.0
CMS2_k127_3421719_4 - - - - 0.00000000002648 70.0
CMS2_k127_3477979_0 Abc transporter K06158 - - 1.693e-298 925.0
CMS2_k127_3477979_1 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 343.0
CMS2_k127_3477979_2 Histidine kinase HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 343.0
CMS2_k127_3477979_3 COG2518 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000002864 211.0
CMS2_k127_3477979_4 chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000004975 219.0
CMS2_k127_3477979_5 - - - - 0.000000000000000000000832 98.0
CMS2_k127_3477979_6 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.000000004619 57.0
CMS2_k127_3483272_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.191e-224 712.0
CMS2_k127_3483272_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 327.0
CMS2_k127_3483272_2 COGs COG0665 Glycine D-amino acid oxidase (deaminating) K15461 - 2.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001515 278.0
CMS2_k127_3483272_3 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000001406 192.0
CMS2_k127_3498897_0 DNA helicase K03657 - 3.6.4.12 6.483e-252 788.0
CMS2_k127_3498897_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090 - 2.355e-219 702.0
CMS2_k127_3498897_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 544.0
CMS2_k127_3498897_3 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0000000000000000000000000005109 117.0
CMS2_k127_3498897_4 SMART GGDEF domain containing protein - - - 0.0000000000000000000000001306 118.0
CMS2_k127_3498897_5 COG0436 Aspartate tyrosine aromatic aminotransferase - - - 0.0000000000000000000001396 98.0
CMS2_k127_3498897_6 - - - - 0.00000000001763 71.0
CMS2_k127_3498897_7 AF0941-like - - - 0.000000001796 62.0
CMS2_k127_3504281_0 Chromate K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 432.0
CMS2_k127_3504281_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 396.0
CMS2_k127_3504281_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 340.0
CMS2_k127_3504281_3 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 304.0
CMS2_k127_3504281_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 292.0
CMS2_k127_3504281_5 homoserine kinase type II (Protein kinase fold) K02204 - 2.7.1.39 0.00000000000000000000000000000000000000005053 165.0
CMS2_k127_3514204_0 Glycerol-3-phosphate dehydrogenase K11473 - - 2.852e-201 631.0
CMS2_k127_3514204_1 S1 domain K00243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003427 277.0
CMS2_k127_3514204_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000001169 245.0
CMS2_k127_3514204_3 PFAM DsrE DsrF-like family - - - 0.00000000000000000000000000000000000000000000001268 173.0
CMS2_k127_3514204_4 protein conserved in bacteria K09858 - - 0.000000000000000000000008777 108.0
CMS2_k127_3514204_5 Chemotaxis phosphatase CheX - - - 0.0000000000000000000263 105.0
CMS2_k127_3514204_6 abc transporter atp-binding protein - - - 0.00000221 49.0
CMS2_k127_35608_0 SMART metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 457.0
CMS2_k127_35608_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 361.0
CMS2_k127_35608_2 COG0642 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000007177 188.0
CMS2_k127_35608_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000009564 102.0
CMS2_k127_3589138_0 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 607.0
CMS2_k127_3589138_1 Four helix bundle sensory module for signal transduction - - - 0.0000000003404 70.0
CMS2_k127_3591324_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.89e-243 754.0
CMS2_k127_3591324_1 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 2.052e-194 611.0
CMS2_k127_3591324_10 AMIN domain - - - 0.00000000000000000000000000000000000001525 151.0
CMS2_k127_3591324_11 Flagellar biosynthetic protein FliQ K02420 - - 0.00000000000000000000000000000000004844 135.0
CMS2_k127_3591324_12 - - - - 0.000000000000000000000000000000005637 132.0
CMS2_k127_3591324_13 endonuclease containing a URI domain K07461 - - 0.0000000000000000000000000006318 115.0
CMS2_k127_3591324_14 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000008381 113.0
CMS2_k127_3591324_15 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000002056 118.0
CMS2_k127_3591324_16 - - - - 0.000000000000000000000000006265 115.0
CMS2_k127_3591324_17 - - - - 0.0000000001507 66.0
CMS2_k127_3591324_18 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000592 63.0
CMS2_k127_3591324_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 563.0
CMS2_k127_3591324_3 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 530.0
CMS2_k127_3591324_4 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 503.0
CMS2_k127_3591324_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 421.0
CMS2_k127_3591324_6 DNA recombination protein K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 358.0
CMS2_k127_3591324_7 cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 306.0
CMS2_k127_3591324_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 304.0
CMS2_k127_3591324_9 Pfam Methyltransferase - - - 0.000000000000000000000000000000000000000000000002472 179.0
CMS2_k127_363108_0 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 1.664e-221 717.0
CMS2_k127_363108_1 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 490.0
CMS2_k127_363108_2 COG3893 inactivated superfamily I helicase - - - 0.000000000000000000000000000000000000000000000000000000000000000001363 236.0
CMS2_k127_363108_3 mandelate racemase muconate lactonizing K01684,K08323,K19802 - 4.2.1.6,4.2.1.8,5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000002083 241.0
CMS2_k127_363108_4 Protein of unknown function (DUF3015) - - - 0.000000000000000000000000000000000000000000000001021 178.0
CMS2_k127_3636882_0 Belongs to the 5'-nucleotidase family K01119,K17224 - 3.1.3.6,3.1.4.16 0.0 1056.0
CMS2_k127_3636882_1 chemotaxis protein K03406 - - 7.712e-237 751.0
CMS2_k127_3636882_10 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000002235 180.0
CMS2_k127_3636882_11 oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000000000000000003279 166.0
CMS2_k127_3636882_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 434.0
CMS2_k127_3636882_3 Receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 415.0
CMS2_k127_3636882_4 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 357.0
CMS2_k127_3636882_5 phosphorelay sensor kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 345.0
CMS2_k127_3636882_6 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000000000000000000000004248 238.0
CMS2_k127_3636882_7 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000009679 232.0
CMS2_k127_3636882_8 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000000000000002139 222.0
CMS2_k127_3636882_9 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000818 178.0
CMS2_k127_3653193_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00367,K00372,K08356 - 1.20.2.1,1.20.9.1,1.7.7.2 0.0 1116.0
CMS2_k127_3653193_1 4Fe-4S dicluster domain K07307 - - 6.787e-200 635.0
CMS2_k127_3653193_2 of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000004569 206.0
CMS2_k127_3666487_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1160.0
CMS2_k127_3666487_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 487.0
CMS2_k127_3666487_2 - - - - 0.000000000000000000000000000000000000000000000000719 180.0
CMS2_k127_3772408_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1003.0
CMS2_k127_3772408_1 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 596.0
CMS2_k127_3772408_2 Two-component sensor histidine kinase response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 440.0
CMS2_k127_3772408_3 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 418.0
CMS2_k127_3772408_4 Small-Conductance Mechanosensitive Channel - - - 0.00000000000000000000000000000000000003714 148.0
CMS2_k127_3772408_6 - - - - 0.0000002968 53.0
CMS2_k127_3772408_8 Phosphate-starvation-inducible E - - - 0.0006611 48.0
CMS2_k127_3806800_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 395.0
CMS2_k127_3806800_1 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009827 368.0
CMS2_k127_3806800_2 ADP-ribose pyrophosphatase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000001256 195.0
CMS2_k127_3806800_3 - - - - 0.0000000000000000000726 96.0
CMS2_k127_3806800_4 G/U mismatch-specific uracil-DNA glycosylase activity K03649 - 3.2.2.28 0.00000000000001259 82.0
CMS2_k127_3834473_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.225e-200 635.0
CMS2_k127_3834473_1 Membrane-bound lytic murein transglycosylase C K08306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 338.0
CMS2_k127_3834473_10 LPP20 lipoprotein - - - 0.0000000000001786 78.0
CMS2_k127_3834473_2 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 322.0
CMS2_k127_3834473_3 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000004275 180.0
CMS2_k127_3834473_4 membrane K08973 - - 0.00000000000000000000000000000000000000000001008 166.0
CMS2_k127_3834473_5 membrane K15270 - - 0.00000000000000000000000000000000000000000001999 165.0
CMS2_k127_3834473_6 Domain of unknown function (DUF4393) - - - 0.000000000000000000000000000000000000000002587 165.0
CMS2_k127_3834473_7 LPP20 lipoprotein - - - 0.000000000000000000000000000000000000004139 153.0
CMS2_k127_3834473_8 Omptin family - - - 0.000000000000000000000000000000004896 139.0
CMS2_k127_3834473_9 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000001777 98.0
CMS2_k127_3842034_0 Cysteine desulfurase K04487 - 2.8.1.7 1.461e-227 708.0
CMS2_k127_3842034_1 ATP synthase K02412 - 3.6.3.14 2.784e-204 643.0
CMS2_k127_3842034_2 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 543.0
CMS2_k127_3842034_3 Glycosyl transferase family 2 K20534 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 468.0
CMS2_k127_3842034_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 437.0
CMS2_k127_3842034_5 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 304.0
CMS2_k127_3842034_6 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000001126 191.0
CMS2_k127_3842034_7 - - - - 0.0000000000000000000000000005024 114.0
CMS2_k127_3842034_8 GtrA-like protein - - - 0.0000000000000000000000003388 109.0
CMS2_k127_3845616_0 glutamine synthetase K01915 - 6.3.1.2 2.022e-302 929.0
CMS2_k127_3845616_1 peptidase U32 family K08303 - - 5.607e-211 662.0
CMS2_k127_3845616_2 histidinol phosphate phosphatase K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 384.0
CMS2_k127_3845616_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000075 217.0
CMS2_k127_3845616_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000002592 203.0
CMS2_k127_3845616_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000001106 154.0
CMS2_k127_3856519_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1044.0
CMS2_k127_3856519_1 M18 family aminopeptidase K01267 - 3.4.11.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008986 433.0
CMS2_k127_3856519_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 411.0
CMS2_k127_3856519_3 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 400.0
CMS2_k127_3856519_4 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000007283 233.0
CMS2_k127_3856519_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000003341 222.0
CMS2_k127_3856519_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000001659 212.0
CMS2_k127_3856519_7 Phosphoesterase K07095 - - 0.000000000000000000000000000000000000000000000000001006 188.0
CMS2_k127_3856519_8 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 GO:0005575,GO:0005576,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000000000000000000000000000000000000000001672 168.0
CMS2_k127_3856519_9 serine threonine protein kinase - - - 0.000000000000000003234 99.0
CMS2_k127_389724_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 546.0
CMS2_k127_389724_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 501.0
CMS2_k127_389724_2 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002529 453.0
CMS2_k127_389724_3 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 400.0
CMS2_k127_389724_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006411 357.0
CMS2_k127_389724_5 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 308.0
CMS2_k127_389724_6 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002099 259.0
CMS2_k127_389724_7 Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000000000000000000004296 163.0
CMS2_k127_389724_8 cytochrome c class I - - - 0.00000000000000002399 87.0
CMS2_k127_3910811_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 385.0
CMS2_k127_3910811_1 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002457 282.0
CMS2_k127_3910811_2 Lipopolysaccharide-assembly - - - 0.000000000008874 66.0
CMS2_k127_3951831_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 460.0
CMS2_k127_3951831_1 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 432.0
CMS2_k127_3951831_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 372.0
CMS2_k127_3951831_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000001739 220.0
CMS2_k127_3951831_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000007894 110.0
CMS2_k127_3958239_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1142.0
CMS2_k127_3958239_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 1.033e-222 696.0
CMS2_k127_3958239_2 3-beta hydroxysteroid dehydrogenase/isomerase family K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000005227 222.0
CMS2_k127_3968491_0 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 480.0
CMS2_k127_3968491_1 HDOD domain - - - 0.000000000000000000000000000000000000000000000003623 178.0
CMS2_k127_3975809_0 COG0402 Cytosine deaminase and related metal-dependent K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 421.0
CMS2_k127_3975809_1 Belongs to the glucose-6-phosphate 1-epimerase family K01792 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001453 286.0
CMS2_k127_3975809_2 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005116 273.0
CMS2_k127_3975809_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000001244 250.0
CMS2_k127_3975809_4 Ceramidase - - - 0.0000000000000000000000000000000000000000000000000000002446 199.0
CMS2_k127_3975809_5 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000008762 167.0
CMS2_k127_3975809_6 proteasome regulatory particle assembly K15503,K15504 - - 0.0000000000000000000000002446 121.0
CMS2_k127_3976451_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 535.0
CMS2_k127_3976451_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009074 433.0
CMS2_k127_3976451_2 RNA-binding protein homologous to eukaryotic snRNP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 375.0
CMS2_k127_3976451_3 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 296.0
CMS2_k127_3976451_4 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 297.0
CMS2_k127_3976451_5 Serine hydrolase K07002 - - 0.000000000000000000000000000000000000000000000000000000001203 205.0
CMS2_k127_3976451_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000007556 85.0
CMS2_k127_3976451_7 - - - - 0.000000000000001413 80.0
CMS2_k127_4079614_0 Inorganic pyrophosphatase K15986 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 432.0
CMS2_k127_4079614_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 373.0
CMS2_k127_4079614_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 328.0
CMS2_k127_4079614_3 B-1 B cell differentiation - - - 0.000000000000000000000000000000000000000000000000000000000000005485 236.0
CMS2_k127_4079614_4 histidine kinase HAMP region domain protein K03406,K05874,K05875 - - 0.00000000000000000000000000000000000000000000000000000829 195.0
CMS2_k127_4079614_5 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.000000000000000000000000000000001427 132.0
CMS2_k127_4090911_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1368.0
CMS2_k127_4090911_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 3.168e-269 835.0
CMS2_k127_4090911_10 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000003083 65.0
CMS2_k127_4090911_11 - - - - 0.0000000005304 61.0
CMS2_k127_4090911_12 - - - - 0.00000001023 56.0
CMS2_k127_4090911_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.724e-250 777.0
CMS2_k127_4090911_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 7.651e-206 647.0
CMS2_k127_4090911_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 547.0
CMS2_k127_4090911_5 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 518.0
CMS2_k127_4090911_6 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 341.0
CMS2_k127_4090911_7 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 331.0
CMS2_k127_4090911_8 hydrolase K01501 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 299.0
CMS2_k127_4090911_9 Receptor - - - 0.000000000000000000000000003827 114.0
CMS2_k127_413904_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1108.0
CMS2_k127_413904_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003809 252.0
CMS2_k127_4152145_0 RNA binding S1 domain protein K06959 - - 2.727e-269 846.0
CMS2_k127_4152145_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 350.0
CMS2_k127_4152145_2 COG2199 FOG GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000001947 221.0
CMS2_k127_4152145_4 3'-5' exonuclease - - - 0.00000000000000000000000000005009 126.0
CMS2_k127_4209121_0 ATP-dependent DNA helicase K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 550.0
CMS2_k127_4209121_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 289.0
CMS2_k127_4209121_2 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.000000000000000000000000000000000000000000000000000000000001203 214.0
CMS2_k127_4209121_3 Prepilin-type N-terminal cleavage methylation domain - - - 0.00000000000000000000000000000000000000000000000000003143 199.0
CMS2_k127_4209121_4 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.000000000000000000000000000000000005617 141.0
CMS2_k127_4209121_5 - - - - 0.0000000000000000000000000003161 119.0
CMS2_k127_4209121_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000007406 101.0
CMS2_k127_4209121_7 Conserved repeat domain - - - 0.0000000000000000000009835 112.0
CMS2_k127_4209121_8 type IV pilus modification protein PilV - - - 0.000000000000002662 84.0
CMS2_k127_4209121_9 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000001805 85.0
CMS2_k127_4249577_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 338.0
CMS2_k127_4249577_1 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002203 297.0
CMS2_k127_4249577_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008982 256.0
CMS2_k127_4249577_3 Uncharacterised signal transduction histidine kinase domain (DUF2222) - - - 0.00000000000000000000000000000000000001657 160.0
CMS2_k127_4249577_4 - - - - 0.0000000000000000000000000000000000001044 148.0
CMS2_k127_4249577_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000001271 139.0
CMS2_k127_4256057_0 arginine decarboxylase K01585 - 4.1.1.19 7.37e-248 778.0
CMS2_k127_4256057_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.144e-235 731.0
CMS2_k127_4256057_2 COGs COG0069 Glutamate synthase domain 2 - - - 1.402e-234 738.0
CMS2_k127_4256057_3 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 576.0
CMS2_k127_4256057_4 serine acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 351.0
CMS2_k127_4256057_5 K -dependent Na Ca exchanger K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003515 338.0
CMS2_k127_4256057_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000702 255.0
CMS2_k127_4256057_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000503 222.0
CMS2_k127_4256057_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000001205 186.0
CMS2_k127_4256057_9 Chaperone for flagella basal body P-ring formation K02386 - - 0.0000000000000000000000000000005848 133.0
CMS2_k127_4306602_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 600.0
CMS2_k127_4306602_1 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009975 346.0
CMS2_k127_4306602_2 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001912 237.0
CMS2_k127_4306602_3 - - - - 0.00000000000000000000000003246 110.0
CMS2_k127_4306602_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000001225 113.0
CMS2_k127_4306602_5 GHKL domain - - - 0.0000000000001232 74.0
CMS2_k127_4306602_6 Pfam Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000001893 53.0
CMS2_k127_4311033_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 551.0
CMS2_k127_4311033_1 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 316.0
CMS2_k127_4311033_2 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 286.0
CMS2_k127_4311033_3 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000000000000001727 171.0
CMS2_k127_4311033_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000002908 141.0
CMS2_k127_4311033_5 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000001435 132.0
CMS2_k127_4311033_6 nucleotidyltransferase activity K07075 - - 0.0000000004807 61.0
CMS2_k127_4339190_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 368.0
CMS2_k127_4339190_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001039 234.0
CMS2_k127_4339190_2 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000001912 240.0
CMS2_k127_4339190_3 - - - - 0.0000000000000000000000000000000000000000000000007205 182.0
CMS2_k127_4339190_4 -acetyltransferase K06975 - - 0.0000000000000000000000000000009888 123.0
CMS2_k127_4339190_5 - - - - 0.0000000000000000000000006507 111.0
CMS2_k127_4339190_6 SCO1/SenC K07152 - - 0.000000000000687 76.0
CMS2_k127_4339190_7 Protein of unknown function (DUF2986) - - - 0.00001542 50.0
CMS2_k127_4369453_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009507,GO:0009536,GO:0009611,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0050896,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 5.442e-222 695.0
CMS2_k127_4369453_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 516.0
CMS2_k127_4369453_10 - - - - 0.00000000000000000000000000000000000000000000002677 183.0
CMS2_k127_4369453_11 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000002719 159.0
CMS2_k127_4369453_12 Belongs to the ArsC family - - - 0.0000000000000000000000000000007996 124.0
CMS2_k127_4369453_13 - - - - 0.000000000000000000000000001472 121.0
CMS2_k127_4369453_14 Cytochrome c - - - 0.00000000000000000000000004641 111.0
CMS2_k127_4369453_15 - - - - 0.000000000000000002877 88.0
CMS2_k127_4369453_16 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000001039 87.0
CMS2_k127_4369453_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009855 437.0
CMS2_k127_4369453_3 Histidine kinase K02482,K07710 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 350.0
CMS2_k127_4369453_4 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 340.0
CMS2_k127_4369453_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 332.0
CMS2_k127_4369453_6 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 310.0
CMS2_k127_4369453_7 hmm pf04305 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005413 266.0
CMS2_k127_4369453_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000009095 187.0
CMS2_k127_4369453_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000198 172.0
CMS2_k127_4379092_0 COG4886 Leucine-rich repeat (LRR) protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 541.0
CMS2_k127_4379092_1 PFAM CheW domain protein - - - 0.00000000000000000000000000000000000000000000000000000000452 206.0
CMS2_k127_4379092_2 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.0000000000000000000000000000000000000000000000005432 179.0
CMS2_k127_4388344_0 Heat shock 70 kDa protein K04043 - - 1.137e-264 827.0
CMS2_k127_4388344_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 595.0
CMS2_k127_4388344_2 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 410.0
CMS2_k127_4388344_3 lytic murein transglycosylase K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 321.0
CMS2_k127_4388344_4 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000000000000000001332 236.0
CMS2_k127_4388344_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000001642 224.0
CMS2_k127_4388344_6 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000003104 172.0
CMS2_k127_4388344_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000004582 162.0
CMS2_k127_4388344_8 YGGT family K02221 - - 0.0000000000000000000000001263 108.0
CMS2_k127_4388344_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00001172 55.0
CMS2_k127_439789_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 438.0
CMS2_k127_439789_1 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 419.0
CMS2_k127_439789_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008817 392.0
CMS2_k127_439789_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 346.0
CMS2_k127_439789_4 RNase H K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 316.0
CMS2_k127_439789_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 301.0
CMS2_k127_439789_6 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000005919 229.0
CMS2_k127_439789_7 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000001534 139.0
CMS2_k127_439789_8 phosphorelay signal transduction system - - - 0.000000000000000000000000002126 125.0
CMS2_k127_4484785_0 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K00595,K02191 - 2.1.1.132,2.1.1.196 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 370.0
CMS2_k127_4484785_1 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 335.0
CMS2_k127_4484785_2 PFAM cobalamin (vitamin B12) biosynthesis CbiG K02189 - 3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 315.0
CMS2_k127_4484785_3 Tetrapyrrole (Corrin/Porphyrin) Methylases K02232,K05934,K05936,K13541 - 2.1.1.131,2.1.1.133,2.1.1.271,3.7.1.12,6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 295.0
CMS2_k127_4484785_4 precorrin-2 c20-methyltransferase K02190,K02228,K03394,K13540 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.1.1.130,2.1.1.131,2.1.1.151,2.1.1.152,4.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001015 265.0
CMS2_k127_4484785_5 precorrin-2 dehydrogenase activity K02302,K02303,K02304,K13541,K13542 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,2.1.1.131,3.7.1.12,4.2.1.75,4.99.1.4 0.000000000000000000000000000000006963 133.0
CMS2_k127_4490718_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.01e-215 674.0
CMS2_k127_4490718_1 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 533.0
CMS2_k127_4490718_2 PFAM tRNA synthetase class II (G H P and S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 328.0
CMS2_k127_4490718_3 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 301.0
CMS2_k127_4490718_4 COG1393 Arsenate reductase and related K00537 - 1.20.4.1 0.000000000000000000000000000000000002444 141.0
CMS2_k127_4490718_5 PDP protein - - - 0.00000000000000000000000000000001656 132.0
CMS2_k127_4490718_6 Flagellar FliJ protein - - - 0.000000000005559 71.0
CMS2_k127_4504577_0 COG0659 Sulfate permease and related K03321 - - 2.061e-206 653.0
CMS2_k127_4504577_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 577.0
CMS2_k127_4504577_2 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 340.0
CMS2_k127_4504577_3 7TM diverse intracellular signalling K20971 - - 0.000000000000000000000000000000000000000000000000000000000000000000001184 261.0
CMS2_k127_4504577_4 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000001509 141.0
CMS2_k127_4504577_5 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000923 128.0
CMS2_k127_4504577_6 cAMP-dependent protein kinase regulatory subunit K04739 GO:0000003,GO:0000166,GO:0000228,GO:0000785,GO:0000790,GO:0001932,GO:0001933,GO:0002831,GO:0002832,GO:0003674,GO:0004857,GO:0004860,GO:0004862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005886,GO:0005952,GO:0006469,GO:0006950,GO:0006979,GO:0007154,GO:0008104,GO:0008150,GO:0008277,GO:0008603,GO:0009266,GO:0009267,GO:0009405,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009653,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010563,GO:0010570,GO:0010605,GO:0010639,GO:0010646,GO:0010648,GO:0016020,GO:0017076,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019954,GO:0022603,GO:0023051,GO:0023057,GO:0030154,GO:0030234,GO:0030291,GO:0030435,GO:0030436,GO:0030447,GO:0030448,GO:0030551,GO:0030552,GO:0030554,GO:0031279,GO:0031281,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0031667,GO:0031668,GO:0031669,GO:0031974,GO:0031981,GO:0032101,GO:0032102,GO:0032104,GO:0032105,GO:0032107,GO:0032108,GO:0032268,GO:0032269,GO:0032386,GO:0032388,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032879,GO:0032880,GO:0032991,GO:0033036,GO:0033043,GO:0033157,GO:0033554,GO:0033673,GO:0034305,GO:0034599,GO:0034605,GO:0034613,GO:0036094,GO:0036170,GO:0036180,GO:0040007,GO:0040008,GO:0042173,GO:0042221,GO:0042325,GO:0042326,GO:0042594,GO:0043085,GO:0043086,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043549,GO:0043934,GO:0043936,GO:0043937,GO:0043938,GO:0043943,GO:0043945,GO:0043949,GO:0043951,GO:0044092,GO:0044093,GO:0044182,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0045595,GO:0045597,GO:0045744,GO:0045761,GO:0045762,GO:0045786,GO:0045859,GO:0045881,GO:0045926,GO:0045936,GO:0046578,GO:0046580,GO:0046822,GO:0046824,GO:0046825,GO:0046827,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048646,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051049,GO:0051050,GO:0051056,GO:0051058,GO:0051094,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051246,GO:0051248,GO:0051338,GO:0051339,GO:0051348,GO:0051349,GO:0051445,GO:0051447,GO:0051641,GO:0051704,GO:0051716,GO:0051726,GO:0051783,GO:0051784,GO:0060255,GO:0060258,GO:0060341,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070201,GO:0070727,GO:0070887,GO:0071496,GO:0071900,GO:0071901,GO:0071944,GO:0080090,GO:0080134,GO:0090087,GO:0090316,GO:0097159,GO:0097271,GO:0097367,GO:0098772,GO:0106070,GO:0106072,GO:0110033,GO:0110034,GO:1900428,GO:1900429,GO:1900434,GO:1900435,GO:1900443,GO:1900444,GO:1901265,GO:1901363,GO:1902531,GO:1902532,GO:1902659,GO:1902660,GO:1903664,GO:1903666,GO:1903827,GO:1903829,GO:1904951,GO:2000241,GO:2000242,GO:2000479,GO:2000480 - 0.0001078 52.0
CMS2_k127_4509934_0 flagellar motor switch protein K02416 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 533.0
CMS2_k127_4509934_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 526.0
CMS2_k127_4509934_2 flagellar biosynthesis K02404 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 526.0
CMS2_k127_4509934_3 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006425 333.0
CMS2_k127_4509934_4 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 309.0
CMS2_k127_4509934_5 Belongs to the sigma-70 factor family K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 293.0
CMS2_k127_4509934_6 flagellar motor switch protein K02417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003108 273.0
CMS2_k127_4509934_7 - - - - 0.0000000000103 69.0
CMS2_k127_4533677_0 phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 575.0
CMS2_k127_4533677_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 533.0
CMS2_k127_4533677_10 negative regulation of translational initiation - - - 0.00000000003364 69.0
CMS2_k127_4533677_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009244 527.0
CMS2_k127_4533677_3 Belongs to the UPF0324 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 419.0
CMS2_k127_4533677_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 318.0
CMS2_k127_4533677_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000001647 238.0
CMS2_k127_4533677_6 Mannosyl-glycoprotein K03796 - - 0.00000000000000000000000000000000000000000000000000002416 198.0
CMS2_k127_4533677_7 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000005061 166.0
CMS2_k127_4533677_8 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000000002649 115.0
CMS2_k127_4533677_9 - K07221 - - 0.000000000000001183 81.0
CMS2_k127_4538870_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 464.0
CMS2_k127_4538870_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 453.0
CMS2_k127_4538870_2 - K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 427.0
CMS2_k127_4538870_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000003556 222.0
CMS2_k127_4538870_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07646 - 2.7.13.3 0.00000000004156 71.0
CMS2_k127_4597221_0 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006037 396.0
CMS2_k127_4597221_1 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 345.0
CMS2_k127_4597221_2 COGs COG3864 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001161 280.0
CMS2_k127_4597221_3 Zn-ribbon-containing protein involved in phosphonate metabolism K06193 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003716 257.0
CMS2_k127_4597221_4 Domain of unknown function DUF302 - - - 0.000000000000000000000000000001666 132.0
CMS2_k127_4597221_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000005707 57.0
CMS2_k127_4653771_0 GTP-binding protein K06207 - - 0.0 1060.0
CMS2_k127_4653771_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1007.0
CMS2_k127_4653771_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000002847 259.0
CMS2_k127_4653771_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000005081 209.0
CMS2_k127_4653771_4 (EAL) domain protein - - - 0.000000000000000000000000000000000000000000005097 181.0
CMS2_k127_4653771_5 TraB family K09973 - - 0.0000000000000000000000000000000000000413 156.0
CMS2_k127_4671403_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.554e-265 831.0
CMS2_k127_4671403_1 AsmA-like C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 320.0
CMS2_k127_4671403_2 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0000000000000000000000000000000000000000000000000000000005124 207.0
CMS2_k127_4671403_3 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000000000000000000000000004968 176.0
CMS2_k127_4671403_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000004661 80.0
CMS2_k127_4683603_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.005e-252 786.0
CMS2_k127_4683603_1 flagellar motor switch protein K02410 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 513.0
CMS2_k127_4683603_2 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 479.0
CMS2_k127_4683603_3 flagellar assembly protein FliH K02411 - - 0.00000000000000000000000000000000009948 143.0
CMS2_k127_4719882_0 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 4.217e-257 812.0
CMS2_k127_4719882_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 1.625e-250 790.0
CMS2_k127_4719882_2 abc transporter atp-binding protein K02031,K15587 - 3.6.3.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 286.0
CMS2_k127_4719882_3 DUF218 domain - - - 0.000000000000000000000000000000000000000000323 166.0
CMS2_k127_4843536_0 penicillin-binding protein K05515 - 3.4.16.4 2.596e-239 753.0
CMS2_k127_4843536_1 peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000003357 235.0
CMS2_k127_4843536_2 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000001161 100.0
CMS2_k127_4846624_0 Mitochondrial degradasome RNA helicase subunit C terminal K17675 - 3.6.4.13 1.52e-220 715.0
CMS2_k127_4846624_1 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003377 273.0
CMS2_k127_4846624_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000002554 244.0
CMS2_k127_4846624_3 Diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000002077 198.0
CMS2_k127_4846624_5 Ankyrin 1, erythrocytic K10380,K15502,K15503 - - 0.0000000000000000001019 98.0
CMS2_k127_4846624_6 Ankyrin repeat and sterile alpha motif domain containing 3 - GO:0008150,GO:0018996,GO:0022404,GO:0032501,GO:0042303,GO:0042395 - 0.00000000000005816 78.0
CMS2_k127_4846624_7 ATPase (AAA K07133 - - 0.00005724 46.0
CMS2_k127_4857194_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 542.0
CMS2_k127_4857194_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 322.0
CMS2_k127_4857194_2 PFAM glutaredoxin - - - 0.0000000000000000000000000000001068 129.0
CMS2_k127_4932173_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1639.0
CMS2_k127_4932173_1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K16881 - 2.7.7.13,5.4.2.8 0.0 1062.0
CMS2_k127_4932173_10 ABC transporter K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 497.0
CMS2_k127_4932173_11 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 502.0
CMS2_k127_4932173_12 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 483.0
CMS2_k127_4932173_13 Belongs to the glutaminase family K01425 - 3.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 474.0
CMS2_k127_4932173_14 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 423.0
CMS2_k127_4932173_15 CorA-like Mg2 transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 335.0
CMS2_k127_4932173_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 338.0
CMS2_k127_4932173_17 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 320.0
CMS2_k127_4932173_18 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001247 285.0
CMS2_k127_4932173_19 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000001211 261.0
CMS2_k127_4932173_2 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1053.0
CMS2_k127_4932173_20 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000002889 209.0
CMS2_k127_4932173_21 MarC family integral membrane protein - - - 0.000000000000000000000000000000000000000002823 162.0
CMS2_k127_4932173_23 Protein required for attachment to host cells - - - 0.0000000000000000000000000006919 118.0
CMS2_k127_4932173_24 - - - - 0.00000000000000000001123 94.0
CMS2_k127_4932173_25 diguanylate cyclase - - - 0.0000000000001556 83.0
CMS2_k127_4932173_3 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 6.517e-293 912.0
CMS2_k127_4932173_4 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 1.044e-289 897.0
CMS2_k127_4932173_5 Belongs to the glycosyl hydrolase 57 family - - - 7.804e-266 834.0
CMS2_k127_4932173_6 Belongs to the UPF0061 (SELO) family - - - 7.614e-225 704.0
CMS2_k127_4932173_7 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 2.721e-222 698.0
CMS2_k127_4932173_8 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 541.0
CMS2_k127_4932173_9 Domain of unknown function (DUF389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 537.0
CMS2_k127_4944460_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 3.2e-249 788.0
CMS2_k127_4944460_1 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 602.0
CMS2_k127_4944460_10 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000001677 87.0
CMS2_k127_4944460_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 581.0
CMS2_k127_4944460_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 574.0
CMS2_k127_4944460_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 476.0
CMS2_k127_4944460_5 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 395.0
CMS2_k127_4944460_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 384.0
CMS2_k127_4944460_7 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000158 113.0
CMS2_k127_4944460_8 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000001326 106.0
CMS2_k127_4944460_9 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.0000000000000000000000196 104.0
CMS2_k127_5000632_0 chemotaxis protein K03407 - 2.7.13.3 0.0 1065.0
CMS2_k127_5000632_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1014.0
CMS2_k127_5000632_10 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 309.0
CMS2_k127_5000632_11 involved in molybdopterin and thiamine biosynthesis family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001631 273.0
CMS2_k127_5000632_12 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005998 270.0
CMS2_k127_5000632_13 GHKL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001734 265.0
CMS2_k127_5000632_14 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000002069 228.0
CMS2_k127_5000632_15 chemotaxis protein K03408 - - 0.00000000000000000000000000000000000000000000000000000000001756 210.0
CMS2_k127_5000632_16 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000001592 204.0
CMS2_k127_5000632_17 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000001898 203.0
CMS2_k127_5000632_18 protein conserved in bacteria K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000001807 187.0
CMS2_k127_5000632_19 transformation system protein K02242 - - 0.0000000000000000000000000000000000000000000000008352 180.0
CMS2_k127_5000632_2 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 588.0
CMS2_k127_5000632_20 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000001895 161.0
CMS2_k127_5000632_21 - - - - 0.000000000000000000000000000000000003095 140.0
CMS2_k127_5000632_22 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000003992 126.0
CMS2_k127_5000632_23 WLM domain K07043 - - 0.000000000000000000000005958 109.0
CMS2_k127_5000632_24 protein ubiquitination K15502,K15503 - - 0.00000000000000000000003773 114.0
CMS2_k127_5000632_25 - - - - 0.00008729 50.0
CMS2_k127_5000632_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 531.0
CMS2_k127_5000632_4 chemotaxis protein K03415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 458.0
CMS2_k127_5000632_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 419.0
CMS2_k127_5000632_6 Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 408.0
CMS2_k127_5000632_7 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 352.0
CMS2_k127_5000632_8 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 351.0
CMS2_k127_5000632_9 Nitrite and sulphite reductase 4Fe-4S domain K00366 - 1.7.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 322.0
CMS2_k127_5026110_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1317.0
CMS2_k127_5026110_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 604.0
CMS2_k127_5026110_10 Sel1-like repeats. K07126 - - 0.000000000008292 73.0
CMS2_k127_5026110_2 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000006757 262.0
CMS2_k127_5026110_3 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001608 241.0
CMS2_k127_5026110_4 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000006122 229.0
CMS2_k127_5026110_5 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000002947 185.0
CMS2_k127_5026110_6 Protein conserved in bacteria K09943 - - 0.000000000000000000000000000000000000000000003464 169.0
CMS2_k127_5026110_7 Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000105 150.0
CMS2_k127_5026110_8 Pyridoxamine 5-phosphate - - - 0.000000000000000000000000000002209 127.0
CMS2_k127_5026110_9 TraB family K09973 - - 0.00000000000000000003148 101.0
CMS2_k127_5076876_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.0 1527.0
CMS2_k127_5076876_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1141.0
CMS2_k127_5076876_10 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 408.0
CMS2_k127_5076876_11 TIGRFAM MauM NapG family ferredoxin-type protein K02573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 380.0
CMS2_k127_5076876_12 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 391.0
CMS2_k127_5076876_13 FIST N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 386.0
CMS2_k127_5076876_14 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 361.0
CMS2_k127_5076876_15 Ferredoxin-type protein, NapH MauN family K02574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 347.0
CMS2_k127_5076876_16 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 297.0
CMS2_k127_5076876_17 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004674 269.0
CMS2_k127_5076876_18 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000219 246.0
CMS2_k127_5076876_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000001983 213.0
CMS2_k127_5076876_2 Domain of unknown function (DUF1974) K06445 - - 1.189e-246 786.0
CMS2_k127_5076876_20 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000001316 211.0
CMS2_k127_5076876_21 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000001386 208.0
CMS2_k127_5076876_22 signal transduction sensor histidine kinase - - - 0.00000000000000000000000000000000000000000000000006855 181.0
CMS2_k127_5076876_23 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000004797 184.0
CMS2_k127_5076876_24 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000000000000000000000000000000000000000000007315 175.0
CMS2_k127_5076876_25 nitrate reductase K02570 - - 0.0000000000000000000000000000000000000004083 152.0
CMS2_k127_5076876_26 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000000004565 141.0
CMS2_k127_5076876_27 ferredoxin-type protein NapF K02572 - - 0.00000000000000000000000000000000000182 144.0
CMS2_k127_5076876_28 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000001855 111.0
CMS2_k127_5076876_29 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000005482 104.0
CMS2_k127_5076876_3 DNA RNA helicase - - - 5.604e-236 766.0
CMS2_k127_5076876_4 Enoyl-CoA hydratase/isomerase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 3.341e-206 664.0
CMS2_k127_5076876_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 2.295e-202 643.0
CMS2_k127_5076876_6 phosphorelay signal transduction system K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 488.0
CMS2_k127_5076876_7 Arginosuccinate synthase K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 465.0
CMS2_k127_5076876_8 CheB methylesterase K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 460.0
CMS2_k127_5076876_9 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 456.0
CMS2_k127_5086508_0 AAA domain - - - 4.354e-207 665.0
CMS2_k127_5086508_1 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 362.0
CMS2_k127_5086508_2 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 293.0
CMS2_k127_5086508_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000003015 234.0
CMS2_k127_5086508_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000001817 214.0
CMS2_k127_5086508_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000003597 106.0
CMS2_k127_5152319_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 6.612e-194 610.0
CMS2_k127_5152319_1 Sodium:sulfate symporter transmembrane region K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 560.0
CMS2_k127_5152319_10 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001605 259.0
CMS2_k127_5152319_11 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.000000000000000000000000000000000000000000000000000000000000000001203 230.0
CMS2_k127_5152319_12 Cell division protein FtsX K09811 - - 0.0000000000000000000000000000000000000008835 158.0
CMS2_k127_5152319_13 - - - - 0.00000000000000000000000000000000000004608 147.0
CMS2_k127_5152319_14 VRR_NUC - - - 0.00000000000000000000000000000009912 128.0
CMS2_k127_5152319_15 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000001864 128.0
CMS2_k127_5152319_16 Rod binding protein - - - 0.00000000000000000000000145 105.0
CMS2_k127_5152319_17 Thioesterase superfamily - - - 0.00000003119 61.0
CMS2_k127_5152319_2 flagellar hook-associated protein K02396 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 504.0
CMS2_k127_5152319_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 412.0
CMS2_k127_5152319_4 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005979 405.0
CMS2_k127_5152319_5 Belongs to the DEAD box helicase family K05591 GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008905 379.0
CMS2_k127_5152319_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 361.0
CMS2_k127_5152319_7 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034,K12370 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 356.0
CMS2_k127_5152319_8 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 330.0
CMS2_k127_5152319_9 Fibronectin type 3 domain-containing protein K06882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 294.0
CMS2_k127_5154965_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.056e-209 654.0
CMS2_k127_5154965_1 Radical SAM protein K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 443.0
CMS2_k127_5189011_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1497.0
CMS2_k127_5189011_1 COG0155 Sulfite reductase, beta subunit (hemoprotein) K00366,K00392 - 1.7.7.1,1.8.7.1 4.425e-247 779.0
CMS2_k127_5189011_2 COG2223 Nitrate nitrite transporter K02575 - - 5.409e-226 706.0
CMS2_k127_5189011_3 COG0631 Serine threonine protein phosphatase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 597.0
CMS2_k127_5189011_4 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001911 284.0
CMS2_k127_5189011_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009158 283.0
CMS2_k127_5189011_6 phosphorelay signal transduction system K01768,K07315 GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000006005 143.0
CMS2_k127_5207609_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 410.0
CMS2_k127_5207609_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 380.0
CMS2_k127_5207609_2 transmembrane signaling receptor activity - - - 0.000000000000000000000000000000000000000000000000000000000000002033 224.0
CMS2_k127_5207609_3 BFD-like [2Fe-2S] binding domain - - - 0.0000000115 65.0
CMS2_k127_5215281_0 Na Pi-cotransporter K03324 - - 2.885e-260 813.0
CMS2_k127_5215281_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000269 285.0
CMS2_k127_5215281_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007735 280.0
CMS2_k127_5215281_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000002122 224.0
CMS2_k127_5215281_5 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000002293 201.0
CMS2_k127_5215281_6 Histidine Phosphotransfer domain - - - 0.0000000000006417 83.0
CMS2_k127_5232885_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 513.0
CMS2_k127_5232885_1 B-1 B cell differentiation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 367.0
CMS2_k127_5232885_3 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000006849 227.0
CMS2_k127_5232885_4 Protein of unknown function (DUF819) - - - 0.00000000000000000000000000000000000000000000000000000000000005235 227.0
CMS2_k127_5232885_5 PAS fold K03776 - - 0.0000000000000000000000000000000000000000000000005458 178.0
CMS2_k127_5232885_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000004959 142.0
CMS2_k127_5267780_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 368.0
CMS2_k127_5267780_1 Chemotaxis protein CheW K03408 - - 0.0000000000000000000000000000000000000000000006791 169.0
CMS2_k127_5281708_0 Ribonuclease K12573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 563.0
CMS2_k127_5281708_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 537.0
CMS2_k127_5281708_10 Transcriptional regulator - - - 0.0000000000000000000000000000005625 126.0
CMS2_k127_5281708_12 Uncharacterised protein family (UPF0227) K07000 - - 0.000008418 55.0
CMS2_k127_5281708_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 541.0
CMS2_k127_5281708_3 Signal transduction protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 301.0
CMS2_k127_5281708_4 Jag_N K06346 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001842 266.0
CMS2_k127_5281708_5 DNA polymerase III K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000002568 258.0
CMS2_k127_5281708_6 - - - - 0.00000000000000000000000000000000000000000000000000009776 194.0
CMS2_k127_5281708_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000001335 168.0
CMS2_k127_5281708_8 fatty acid desaturase - - - 0.0000000000000000000000000000000000001782 153.0
CMS2_k127_5281708_9 Domain of unknown function (DUF4395) - - - 0.0000000000000000000000000000004466 126.0
CMS2_k127_5296733_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 413.0
CMS2_k127_5296733_1 protein conserved in bacteria K09778 - - 0.000000000000000000000000000000000000000000002929 171.0
CMS2_k127_5296733_2 - - - - 0.0000000000000000000000009598 109.0
CMS2_k127_5324997_0 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 1.418e-195 633.0
CMS2_k127_5324997_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 602.0
CMS2_k127_5324997_11 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.0000002742 61.0
CMS2_k127_5324997_2 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 381.0
CMS2_k127_5324997_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 302.0
CMS2_k127_5324997_4 Belongs to the 'phage' integrase family K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003953 269.0
CMS2_k127_5324997_5 PFAM Fimbrial assembly family protein - - - 0.000000000000000000000000000000000000001224 153.0
CMS2_k127_5324997_6 DnaJ domain protein K03686 - - 0.00000000000000000000000000000000000001964 153.0
CMS2_k127_5324997_7 - - - - 0.0000000000000000000000000000000001636 146.0
CMS2_k127_5324997_8 - - - - 0.00000000000000000000000000000001836 133.0
CMS2_k127_5332647_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 6.299e-213 677.0
CMS2_k127_5332647_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 309.0
CMS2_k127_5332647_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000001701 79.0
CMS2_k127_5332647_3 Nucleotidyltransferase DNA polymerase involved in DNA repair K02346 - 2.7.7.7 0.0001318 46.0
CMS2_k127_5374823_0 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 607.0
CMS2_k127_5374823_1 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 310.0
CMS2_k127_5374823_2 GTP-binding protein K06207 - - 0.0000000000000000000000000000000000000000000000000000000003738 203.0
CMS2_k127_5374823_3 cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000000000000003275 192.0
CMS2_k127_5374823_4 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000949 186.0
CMS2_k127_5374823_5 Transcriptional regulator K03892 - - 0.000000000000000000000000000000003168 138.0
CMS2_k127_5400856_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.266e-283 895.0
CMS2_k127_5400856_1 peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 479.0
CMS2_k127_5400856_10 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.00000000000000001365 90.0
CMS2_k127_5400856_11 nucleic-acid-binding protein implicated in transcription termination - - - 0.00000000000001752 76.0
CMS2_k127_5400856_2 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 438.0
CMS2_k127_5400856_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009894 408.0
CMS2_k127_5400856_4 riboflavin biosynthesis protein K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 328.0
CMS2_k127_5400856_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000005154 205.0
CMS2_k127_5400856_6 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000002337 181.0
CMS2_k127_5400856_7 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000388 153.0
CMS2_k127_5400856_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000005109 149.0
CMS2_k127_5400856_9 COG1214 Inactive homolog of metal-dependent proteases - - - 0.000000000000000000000000000000000007869 141.0
CMS2_k127_5402636_0 ATP-dependent CLP protease ATP-binding subunit K03694 - - 4.23e-294 918.0
CMS2_k127_5402636_1 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 4.378e-202 638.0
CMS2_k127_5402636_10 protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000554 166.0
CMS2_k127_5402636_11 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000002108 124.0
CMS2_k127_5402636_12 Biopolymer transporter ExbB K03561 - - 0.00000000000000000000000000215 115.0
CMS2_k127_5402636_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000002969 114.0
CMS2_k127_5402636_2 O-acetylhomoserine sulfhydrylase K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 552.0
CMS2_k127_5402636_3 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008097 526.0
CMS2_k127_5402636_4 coproporphyrinogen III oxidase K00228 GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 428.0
CMS2_k127_5402636_5 Specifically methylates the adenine in position 1618 of 23S rRNA K06970 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008988,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0052907,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 360.0
CMS2_k127_5402636_6 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000006138 258.0
CMS2_k127_5402636_7 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0016874,GO:0016879,GO:0016882 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000001303 213.0
CMS2_k127_5402636_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000002347 195.0
CMS2_k127_5402636_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000001304 190.0
CMS2_k127_5410068_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 1.08e-275 872.0
CMS2_k127_5410068_1 DinB superfamily K18912 - 1.14.99.50 7.298e-248 783.0
CMS2_k127_5410068_10 (HIT) family - - - 0.00000000000000000000000000000000004222 138.0
CMS2_k127_5410068_11 - - - - 0.0000000000000000000000000002802 119.0
CMS2_k127_5410068_12 - - - - 0.0000000000000000000000009479 108.0
CMS2_k127_5410068_13 Bacitracin ABC transporter ATP-binding protein K20459 - - 0.000000000000000000000002045 110.0
CMS2_k127_5410068_14 - - - - 0.00000000000006237 72.0
CMS2_k127_5410068_15 TIGRFAM prepilin-type N-terminal cleavage methylation domain K02456 - - 0.000000002749 66.0
CMS2_k127_5410068_16 Histone H1 - - - 0.0001682 46.0
CMS2_k127_5410068_2 Belongs to the DEAD box helicase family K05592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 6.091e-198 632.0
CMS2_k127_5410068_3 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 585.0
CMS2_k127_5410068_4 cAMP phosphodiesterases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 523.0
CMS2_k127_5410068_5 Aminotransferase class I and II K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000235 288.0
CMS2_k127_5410068_6 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001077 274.0
CMS2_k127_5410068_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000007144 241.0
CMS2_k127_5410068_8 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000104 203.0
CMS2_k127_5410068_9 - - - - 0.0000000000000000000000000000000000000000000000000006659 190.0
CMS2_k127_5413270_0 acetolactate synthase K01652 - 2.2.1.6 6.147e-291 900.0
CMS2_k127_5413270_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 340.0
CMS2_k127_5413270_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 346.0
CMS2_k127_5413270_3 acetolactate synthase K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000003908 231.0
CMS2_k127_5413270_4 - - - - 0.0000000000000000000000003454 106.0
CMS2_k127_5413270_5 - - - - 0.000000000000000000005456 101.0
CMS2_k127_5458674_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 569.0
CMS2_k127_5458674_1 dihydropteroate synthase K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 468.0
CMS2_k127_5458674_2 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 344.0
CMS2_k127_5478507_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002522 281.0
CMS2_k127_5478507_1 General glycosylation pathway protein - - - 0.00000000000000000000000000000000000000000000000000000000002088 210.0
CMS2_k127_5514728_0 tape measure - - - 0.00000000000000000000000000000000000000000000000000000000003776 235.0
CMS2_k127_5514728_1 response to heat - - - 0.000000000000001923 87.0
CMS2_k127_5568436_0 Heat shock 70 kDa protein K04043 - - 5e-324 999.0
CMS2_k127_5568436_1 UPF0313 protein - - - 2.37e-322 994.0
CMS2_k127_5568436_10 GGDEF domain K03413 - - 0.0000000000000000000000000000000000000001446 153.0
CMS2_k127_5568436_11 Membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000003725 113.0
CMS2_k127_5568436_13 chemotaxis K03408 - - 0.000004737 57.0
CMS2_k127_5568436_2 o-acetylhomoserine K01740 - 2.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 598.0
CMS2_k127_5568436_3 Signal transducing histidine kinase, homodimeric domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 405.0
CMS2_k127_5568436_4 NUBPL iron-transfer P-loop NTPase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 333.0
CMS2_k127_5568436_5 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 301.0
CMS2_k127_5568436_6 membrane-associated protein - - - 0.0000000000000000000000000000000000000000000000000000002751 199.0
CMS2_k127_5568436_7 PFAM response regulator receiver K03407,K03413 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000622 186.0
CMS2_k127_5568436_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000002849 184.0
CMS2_k127_5568436_9 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000002387 156.0
CMS2_k127_5625992_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 535.0
CMS2_k127_5625992_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 425.0
CMS2_k127_5625992_2 Subtilisin-like serine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 290.0
CMS2_k127_5625992_3 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002093 272.0
CMS2_k127_5625992_4 Peptidase M48 K03799 - - 0.00000000000000000000000000000000000000000000000000003348 197.0
CMS2_k127_5625992_5 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000004435 142.0
CMS2_k127_5670900_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 4.791e-256 796.0
CMS2_k127_5670900_1 ribosomal protein S1 K02945 - - 1.141e-235 740.0
CMS2_k127_5670900_2 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 3.656e-233 745.0
CMS2_k127_5670900_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 610.0
CMS2_k127_5670900_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 492.0
CMS2_k127_5670900_5 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 384.0
CMS2_k127_5670900_6 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 322.0
CMS2_k127_5670900_7 - - - - 0.00000000002731 70.0
CMS2_k127_5700244_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 3.392e-275 849.0
CMS2_k127_5700244_1 MMPL family K07003 - - 1.76e-269 851.0
CMS2_k127_5700244_10 Ion transport protein K08714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 323.0
CMS2_k127_5700244_11 Sh3 type 3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 332.0
CMS2_k127_5700244_12 Archaea bacterial proteins of unknown function K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 321.0
CMS2_k127_5700244_13 diguanylate cyclase K13590 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 323.0
CMS2_k127_5700244_14 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 314.0
CMS2_k127_5700244_15 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 309.0
CMS2_k127_5700244_16 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004496 265.0
CMS2_k127_5700244_17 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000002108 239.0
CMS2_k127_5700244_18 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000004477 216.0
CMS2_k127_5700244_19 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000005335 185.0
CMS2_k127_5700244_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.133e-243 764.0
CMS2_k127_5700244_20 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000002616 163.0
CMS2_k127_5700244_21 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000003669 165.0
CMS2_k127_5700244_22 transcriptional regulator - - - 0.00000000000000000000000000000000001681 143.0
CMS2_k127_5700244_23 Ankyrin repeat K10277,K10380 GO:0000902,GO:0000904,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006928,GO:0006935,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0008150,GO:0009605,GO:0009653,GO:0009987,GO:0010171,GO:0016020,GO:0016043,GO:0016328,GO:0022008,GO:0030030,GO:0030154,GO:0030182,GO:0031175,GO:0032501,GO:0032502,GO:0032989,GO:0032990,GO:0033563,GO:0040008,GO:0040011,GO:0040014,GO:0040018,GO:0042221,GO:0042330,GO:0044425,GO:0044459,GO:0044464,GO:0045927,GO:0048468,GO:0048518,GO:0048638,GO:0048639,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0050789,GO:0050793,GO:0050839,GO:0050896,GO:0051094,GO:0051239,GO:0051240,GO:0061564,GO:0065007,GO:0071840,GO:0071944,GO:0097485,GO:0120036,GO:0120039 1.14.11.27 0.000000000000000000000000002122 129.0
CMS2_k127_5700244_25 MOSC domain - - - 0.00000000000000000000006526 102.0
CMS2_k127_5700244_26 Domain of unknown function (DUF2018) - - - 0.00000000000000000008976 92.0
CMS2_k127_5700244_27 Cold shock K03704 - - 0.00000000000000005824 83.0
CMS2_k127_5700244_28 - - - - 0.0000000002828 68.0
CMS2_k127_5700244_29 Two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000329 70.0
CMS2_k127_5700244_3 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 591.0
CMS2_k127_5700244_30 - - - - 0.000000004491 63.0
CMS2_k127_5700244_31 Protein affecting phage T7 exclusion by the F plasmid K07113 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016021,GO:0031224,GO:0044425,GO:0044464,GO:0071944 - 0.0000007104 57.0
CMS2_k127_5700244_32 UbiA prenyltransferase family - - - 0.00006735 46.0
CMS2_k127_5700244_4 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 573.0
CMS2_k127_5700244_5 sulfate adenylyltransferase K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 544.0
CMS2_k127_5700244_6 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 428.0
CMS2_k127_5700244_7 Belongs to the UbiD family K03182 - 4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 375.0
CMS2_k127_5700244_8 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 374.0
CMS2_k127_5700244_9 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 365.0
CMS2_k127_5725927_0 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 2.13e-217 687.0
CMS2_k127_5725927_1 Cytochrome c-552 DMSO reductase-like, heme-binding domain K17052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 361.0
CMS2_k127_5725927_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 357.0
CMS2_k127_5725927_3 fumarate reductase, iron-sulfur protein K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000002713 262.0
CMS2_k127_5725927_4 Nitrate reductase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000006173 237.0
CMS2_k127_5725927_5 - - - - 0.0000000000000000000000000000001617 127.0
CMS2_k127_5725927_6 - - - - 0.000000000000000004201 88.0
CMS2_k127_5725927_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000007198 70.0
CMS2_k127_5761464_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.698e-257 812.0
CMS2_k127_5761464_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.042e-243 760.0
CMS2_k127_5761464_10 molybdopterin converting factor K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000004472 239.0
CMS2_k127_5761464_11 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000000000004062 241.0
CMS2_k127_5761464_12 Belongs to the 'phage' integrase family K14059 - - 0.000000000000000000000000000000000000000000000000000000000000003214 228.0
CMS2_k127_5761464_13 phosphoribosyltransferase K07100 - - 0.0000000000000000000000000000000000000000000000000000000001012 211.0
CMS2_k127_5761464_14 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000001147 138.0
CMS2_k127_5761464_15 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.000000000000000000000000000003351 127.0
CMS2_k127_5761464_16 molybdopterin converting factor K03636 - - 0.0000000000000000000001115 100.0
CMS2_k127_5761464_17 RDD family - - - 0.00000000000000001796 87.0
CMS2_k127_5761464_2 Belongs to the GARS family K01945 - 6.3.4.13 4.39e-204 642.0
CMS2_k127_5761464_3 abc transporter atp-binding protein K06147,K06148 - - 7.399e-201 641.0
CMS2_k127_5761464_4 COG1055 Na H antiporter NhaD and related arsenite - - - 1.366e-198 628.0
CMS2_k127_5761464_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 557.0
CMS2_k127_5761464_6 molybdopterin biosynthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 448.0
CMS2_k127_5761464_7 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 445.0
CMS2_k127_5761464_8 TIGRFAM diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 422.0
CMS2_k127_5761464_9 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 336.0
CMS2_k127_5793479_0 Response regulator receiver K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000862 267.0
CMS2_k127_5793479_1 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000000000000000000002364 141.0
CMS2_k127_5793479_2 - - - - 0.000000000000386 78.0
CMS2_k127_5802524_0 STAS domain K03321 - - 7.463e-223 705.0
CMS2_k127_5802524_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 296.0
CMS2_k127_5802524_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000001055 154.0
CMS2_k127_5870454_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 4.995e-302 938.0
CMS2_k127_5870454_1 Sodium calcium exchanger membrane K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 310.0
CMS2_k127_5870454_2 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000418 132.0
CMS2_k127_5875521_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 2.508e-224 704.0
CMS2_k127_5875521_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.54e-197 621.0
CMS2_k127_5875521_10 HDOD domain - - - 0.000000000000000000000000000000000000000002414 160.0
CMS2_k127_5875521_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000003507 121.0
CMS2_k127_5875521_2 Chemotaxis phosphatase CheX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 521.0
CMS2_k127_5875521_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 509.0
CMS2_k127_5875521_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 510.0
CMS2_k127_5875521_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 447.0
CMS2_k127_5875521_6 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 425.0
CMS2_k127_5875521_7 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 355.0
CMS2_k127_5875521_8 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000004282 256.0
CMS2_k127_5875521_9 dna polymerase iii K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000003197 214.0
CMS2_k127_5917294_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008845 478.0
CMS2_k127_5917294_1 PAS sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002857 235.0
CMS2_k127_5917294_2 chemotaxis protein - - - 0.00000000000000000000000000000000000000000000000001682 190.0
CMS2_k127_5917294_3 - - - - 0.00000000000000009444 81.0
CMS2_k127_5935490_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1255.0
CMS2_k127_5935490_1 Putative diguanylate phosphodiesterase - - - 1.466e-270 844.0
CMS2_k127_5935490_2 Histidine kinase K13040 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 329.0
CMS2_k127_5935490_3 cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 318.0
CMS2_k127_5935490_4 CHASE3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005 290.0
CMS2_k127_5935490_5 ErfK ybiS ycfS ynhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000331 264.0
CMS2_k127_5935490_6 HAMP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000006219 251.0
CMS2_k127_5935490_7 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000594 164.0
CMS2_k127_5935490_8 RESPONSE REGULATOR receiver - - - 0.00000000129 71.0
CMS2_k127_5935490_9 Putative diguanylate phosphodiesterase - - - 0.0002999 44.0
CMS2_k127_5938616_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 597.0
CMS2_k127_5938616_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000532 386.0
CMS2_k127_5938616_2 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 356.0
CMS2_k127_5938616_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009782 348.0
CMS2_k127_5938616_4 D-alanyl-D-alanine carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005068 241.0
CMS2_k127_5938616_5 domain protein K09944 - - 0.000000000000000000000000000000000000000000000002687 178.0
CMS2_k127_6002377_0 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000006927 270.0
CMS2_k127_6002377_1 HAMP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001404 269.0
CMS2_k127_6002377_2 response regulator K07679 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000001122 214.0
CMS2_k127_6002377_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0001924 46.0
CMS2_k127_6010023_0 Hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 459.0
CMS2_k127_6010023_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00244 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 396.0
CMS2_k127_6010023_2 Belongs to the agmatine deiminase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 342.0
CMS2_k127_6010023_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 314.0
CMS2_k127_6010023_4 fumarate reductase K00246 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004151 280.0
CMS2_k127_6010023_5 Nudix domain K08077 - 3.6.1.45 0.00000000000000000000000000000000000000000000000000000000000000000001465 237.0
CMS2_k127_6010023_6 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000104 136.0
CMS2_k127_6010023_7 Rhodanese-like domain - - - 0.0000000000000000000000000000002278 127.0
CMS2_k127_6010023_8 DNA-binding protein - - - 0.0000000000000000000000000000003524 123.0
CMS2_k127_6010616_0 molybdopterin oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 521.0
CMS2_k127_6010616_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 501.0
CMS2_k127_6010616_2 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 365.0
CMS2_k127_6010616_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000008269 117.0
CMS2_k127_6010616_4 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000009532 105.0
CMS2_k127_6024071_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1017.0
CMS2_k127_6024071_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 6.795e-250 773.0
CMS2_k127_6024071_10 - - - - 0.00000002972 57.0
CMS2_k127_6024071_11 - - - - 0.0000009448 51.0
CMS2_k127_6024071_13 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000009607 47.0
CMS2_k127_6024071_2 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 619.0
CMS2_k127_6024071_3 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 361.0
CMS2_k127_6024071_4 cAMP phosphodiesterases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000225 267.0
CMS2_k127_6024071_5 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000005008 223.0
CMS2_k127_6024071_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000000005126 203.0
CMS2_k127_6024071_7 PDZ domain - - - 0.000000000000000000000000000000000001511 151.0
CMS2_k127_6024071_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000001089 132.0
CMS2_k127_6024071_9 PFAM FecR protein - - - 0.00000000000000000000002639 109.0
CMS2_k127_6041878_0 Peptidase family M41 - - - 2.376e-246 784.0
CMS2_k127_6041878_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.458e-206 645.0
CMS2_k127_6041878_10 COGs COG3786 conserved - - - 0.00000000000000000000000000000000000000000001153 170.0
CMS2_k127_6041878_11 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000001501 124.0
CMS2_k127_6041878_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 494.0
CMS2_k127_6041878_3 PFAM Periplasmic binding protein LacI transcriptional regulator K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 382.0
CMS2_k127_6041878_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 357.0
CMS2_k127_6041878_5 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 372.0
CMS2_k127_6041878_6 Na H antiporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 349.0
CMS2_k127_6041878_7 COG0433 Predicted ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 294.0
CMS2_k127_6041878_8 Heme iron utilization protein K07226 - - 0.0000000000000000000000000000000000000000000000000000000000001351 215.0
CMS2_k127_6041878_9 Domain of unknown function (DUF386) - - - 0.000000000000000000000000000000000000000000000000000000325 197.0
CMS2_k127_6052940_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1030.0
CMS2_k127_6052940_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 3.931e-299 928.0
CMS2_k127_6052940_10 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008812 362.0
CMS2_k127_6052940_11 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 361.0
CMS2_k127_6052940_12 Transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 336.0
CMS2_k127_6052940_13 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002861 278.0
CMS2_k127_6052940_14 ubiquinol cytochrome c oxidoreductase, cytochrome c1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003855 264.0
CMS2_k127_6052940_15 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000172 251.0
CMS2_k127_6052940_16 Methyl-accepting chemotaxis protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009008 263.0
CMS2_k127_6052940_17 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000001931 248.0
CMS2_k127_6052940_18 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009345 244.0
CMS2_k127_6052940_19 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000635 223.0
CMS2_k127_6052940_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.358e-245 760.0
CMS2_k127_6052940_20 - - - - 0.000000000000000000000000000000000000000000000000000001653 201.0
CMS2_k127_6052940_21 - - - - 0.000000000000000000000000000000000000000000000000000005731 199.0
CMS2_k127_6052940_22 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000029 192.0
CMS2_k127_6052940_23 - - - - 0.00000000000000000000000000000000000000000000001593 184.0
CMS2_k127_6052940_24 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000158 160.0
CMS2_k127_6052940_25 PFAM EAL domain protein - - - 0.0000000000000000000000000000000000000002173 165.0
CMS2_k127_6052940_26 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000159 152.0
CMS2_k127_6052940_27 PFAM Ferric reductase domain protein transmembrane component domain K17247 - - 0.00000000000000000000000000008425 123.0
CMS2_k127_6052940_28 Protein of unknown function, DUF255 - - - 0.000000000000000000000000002003 115.0
CMS2_k127_6052940_29 Protein of unknown function (DUF493) - - - 0.0000000000000001203 82.0
CMS2_k127_6052940_3 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.22e-235 734.0
CMS2_k127_6052940_30 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.0000000000000001231 90.0
CMS2_k127_6052940_32 response to abiotic stimulus - - - 0.000000992 61.0
CMS2_k127_6052940_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 8.416e-226 707.0
CMS2_k127_6052940_5 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.464e-217 683.0
CMS2_k127_6052940_6 2-acylglycerophosphoethanolamine acyltransferase K05939 - 2.3.1.40,6.2.1.20 1.648e-197 633.0
CMS2_k127_6052940_7 transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 492.0
CMS2_k127_6052940_8 PFAM peptidase M48 Ste24p K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 435.0
CMS2_k127_6052940_9 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 399.0
CMS2_k127_6070174_0 COG4548 Nitric oxide reductase activation protein K02448 - - 4.042e-252 791.0
CMS2_k127_6070174_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.819e-250 784.0
CMS2_k127_6070174_10 Cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000008896 253.0
CMS2_k127_6070174_11 Belongs to the flagella basal body rod proteins family K02388 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004354 246.0
CMS2_k127_6070174_12 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000008677 223.0
CMS2_k127_6070174_13 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000000000000000003189 198.0
CMS2_k127_6070174_14 Domain of unknown function (DUF3943) - - - 0.000000000000000000000000000000000000000000000000000006767 200.0
CMS2_k127_6070174_15 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000000000000000000000000004228 190.0
CMS2_k127_6070174_16 PFAM conserved - - - 0.00000000000000000000000000000000000000000001292 170.0
CMS2_k127_6070174_17 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000006442 170.0
CMS2_k127_6070174_18 - - - - 0.000000000000000000000000000003549 122.0
CMS2_k127_6070174_19 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000000000000009116 117.0
CMS2_k127_6070174_2 Nitric oxide reductase K04561 - 1.7.2.5 1.879e-243 757.0
CMS2_k127_6070174_20 mercuric transport protein - - - 0.0000000007142 65.0
CMS2_k127_6070174_3 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 603.0
CMS2_k127_6070174_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 560.0
CMS2_k127_6070174_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 535.0
CMS2_k127_6070174_6 COG0714 MoxR-like K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 441.0
CMS2_k127_6070174_7 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 317.0
CMS2_k127_6070174_8 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 294.0
CMS2_k127_6070174_9 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000011 284.0
CMS2_k127_6075933_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 480.0
CMS2_k127_6075933_1 abc transporter atp-binding protein K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 317.0
CMS2_k127_6075933_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 294.0
CMS2_k127_6075933_3 Belongs to the protein N5-glutamine methyltransferase family K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001214 274.0
CMS2_k127_6075933_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001841 263.0
CMS2_k127_6075933_5 membrane - - - 0.00000000000000000000000007187 112.0
CMS2_k127_6075933_6 flagellar - - - 0.0000000000000000401 86.0
CMS2_k127_6126245_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 526.0
CMS2_k127_6126245_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 418.0
CMS2_k127_6126245_2 - - - - 0.00000000000000000004719 93.0
CMS2_k127_6130678_0 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0 1070.0
CMS2_k127_6130678_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 5.262e-225 700.0
CMS2_k127_6130678_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000005179 261.0
CMS2_k127_6130678_3 - - - - 0.0000000000000000000000000000000000002234 143.0
CMS2_k127_6130678_4 ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000001058 98.0
CMS2_k127_6192594_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K15576 - - 9.867e-257 796.0
CMS2_k127_6192594_1 COG0600 ABC-type nitrate sulfonate bicarbonate transport system permease component K15577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 430.0
CMS2_k127_6192594_2 ABC transporter K15555,K15578 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 396.0
CMS2_k127_6192594_3 General glycosylation pathway protein - - - 0.000000000000000000000000000000000000000000000000000000000007583 213.0
CMS2_k127_6209215_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2116.0
CMS2_k127_6209215_1 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 9.989e-216 677.0
CMS2_k127_6209215_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000003419 222.0
CMS2_k127_6209215_11 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000001511 211.0
CMS2_k127_6209215_12 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000006631 195.0
CMS2_k127_6209215_13 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000001589 105.0
CMS2_k127_6209215_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 510.0
CMS2_k127_6209215_3 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 482.0
CMS2_k127_6209215_4 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 483.0
CMS2_k127_6209215_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 443.0
CMS2_k127_6209215_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 292.0
CMS2_k127_6209215_7 Permease, YjgP YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005706 281.0
CMS2_k127_6209215_8 Peptidase A24 K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000001185 263.0
CMS2_k127_6209215_9 RecO N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000156 235.0
CMS2_k127_6214874_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 1.587e-259 808.0
CMS2_k127_6214874_1 - - - - 0.000000000000000000000000000000000000401 148.0
CMS2_k127_6214874_2 helicase activity - - - 0.000000000000000000000000001727 119.0
CMS2_k127_6214874_3 dehydrogenase K08325 - - 0.000000007852 57.0
CMS2_k127_63099_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 433.0
CMS2_k127_63099_1 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003315 242.0
CMS2_k127_63099_2 - - - - 0.0000000000000000000000000000009402 128.0
CMS2_k127_63099_5 Histidine Phosphotransfer domain K20976 - - 0.00027 48.0
CMS2_k127_6452767_0 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 325.0
CMS2_k127_6452767_1 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002168 284.0
CMS2_k127_6452767_2 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000004951 216.0
CMS2_k127_6452767_3 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000005495 184.0
CMS2_k127_6452767_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000001865 160.0
CMS2_k127_6452767_5 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000001116 137.0
CMS2_k127_6452767_6 Protein of unknown function, DUF255 - - - 0.000000000000000000000009605 105.0
CMS2_k127_6469274_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 6.766e-195 616.0
CMS2_k127_6469274_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 353.0
CMS2_k127_6469274_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 317.0
CMS2_k127_6469274_3 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 295.0
CMS2_k127_6469274_4 Thioredoxin-like - - - 0.0000000000000000000000000000000004233 134.0
CMS2_k127_6469274_5 - - - - 0.000000000000000000000005603 103.0
CMS2_k127_6469274_6 Histidine kinase K13040 - 2.7.13.3 0.00000000000003711 76.0
CMS2_k127_6499441_0 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 332.0
CMS2_k127_6499441_1 Oxygen tolerance - - - 0.00000000000000000000000000000000000000000000000000000000000004985 232.0
CMS2_k127_650149_0 protein secretion by the type I secretion system K12541 - - 1.613e-206 653.0
CMS2_k127_650149_1 type I secretion membrane fusion protein, HlyD family K02022,K12542 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 365.0
CMS2_k127_6534281_0 phosphorylase kinase alphabeta K07190 - - 0.0 1395.0
CMS2_k127_6534281_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.06e-259 809.0
CMS2_k127_6534281_10 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 442.0
CMS2_k127_6534281_11 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 434.0
CMS2_k127_6534281_12 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 423.0
CMS2_k127_6534281_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000666 400.0
CMS2_k127_6534281_14 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 380.0
CMS2_k127_6534281_15 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 355.0
CMS2_k127_6534281_16 permease K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 304.0
CMS2_k127_6534281_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002072 254.0
CMS2_k127_6534281_18 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000002321 242.0
CMS2_k127_6534281_19 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004564 241.0
CMS2_k127_6534281_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 1.121e-222 703.0
CMS2_k127_6534281_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000005597 229.0
CMS2_k127_6534281_21 NADH-quinone oxidoreductase K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000005886 176.0
CMS2_k127_6534281_22 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000006458 157.0
CMS2_k127_6534281_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000002161 143.0
CMS2_k127_6534281_24 The M ring may be actively involved in energy transduction K02409 - - 0.00000000000000000000000000000000001436 138.0
CMS2_k127_6534281_25 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000004017 118.0
CMS2_k127_6534281_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000008842 104.0
CMS2_k127_6534281_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 599.0
CMS2_k127_6534281_4 Oxidoreductase K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 559.0
CMS2_k127_6534281_5 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 552.0
CMS2_k127_6534281_6 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 521.0
CMS2_k127_6534281_7 Chorismate mutase prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 514.0
CMS2_k127_6534281_8 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 515.0
CMS2_k127_6534281_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 449.0
CMS2_k127_6565479_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.0 1085.0
CMS2_k127_6565479_1 PFAM CheW domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 581.0
CMS2_k127_6565479_2 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 443.0
CMS2_k127_6565479_3 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 376.0
CMS2_k127_6565479_4 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 303.0
CMS2_k127_6565479_5 Prolyl 4-hydroxylase alpha subunit homologues. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 297.0
CMS2_k127_6565479_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000006386 235.0
CMS2_k127_6565479_7 Cupin - - - 0.0000000000000000000000000000000000000000000000000000000001473 205.0
CMS2_k127_6565479_8 PFAM AMMECR1 domain protein K09141 - - 0.000000000000000000000000000000000000000000000000000000001357 205.0
CMS2_k127_6565479_9 that it carries out the mismatch recognition step. This protein has a weak ATPase activity - - - 0.000000000000000000000000001426 121.0
CMS2_k127_6592473_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.482e-281 876.0
CMS2_k127_6592473_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 2.134e-247 788.0
CMS2_k127_6592473_10 - - - - 0.00000000000000000000000001325 114.0
CMS2_k127_6592473_2 diguanylate cyclase - - - 1.265e-208 665.0
CMS2_k127_6592473_3 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002638 576.0
CMS2_k127_6592473_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 509.0
CMS2_k127_6592473_5 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 320.0
CMS2_k127_6592473_6 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000004622 196.0
CMS2_k127_6592473_7 hmm pf01205 - - - 0.0000000000000000000000000000000000000000000000899 174.0
CMS2_k127_6592473_8 response regulator - - - 0.00000000000000000000000000000000000000003858 172.0
CMS2_k127_6592473_9 phosphoribosyltransferase K00769 - 2.4.2.22 0.000000000000000000000000000000008776 132.0
CMS2_k127_6608905_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003448 266.0
CMS2_k127_6608905_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000001399 178.0
CMS2_k127_6608905_2 - - - - 0.00000000000000001193 85.0
CMS2_k127_6608905_3 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000003097 67.0
CMS2_k127_6625498_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0 1909.0
CMS2_k127_6625498_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 526.0
CMS2_k127_6625498_10 TOBE domain - - - 0.000000000000000009947 88.0
CMS2_k127_6625498_2 ATP-binding protein K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 363.0
CMS2_k127_6625498_3 ABC transporter permease K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 299.0
CMS2_k127_6625498_4 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001051 282.0
CMS2_k127_6625498_5 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000008059 254.0
CMS2_k127_6625498_6 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008214 250.0
CMS2_k127_6625498_7 - - - - 0.000000000000000000000000000000000000003062 166.0
CMS2_k127_6625498_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000775 125.0
CMS2_k127_6625498_9 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000007014 101.0
CMS2_k127_6669513_0 Domain of unknown function(DUF2779) - - - 5.328e-214 676.0
CMS2_k127_6669513_1 NfeD-like C-terminal, partner-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 541.0
CMS2_k127_6669513_2 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 505.0
CMS2_k127_6669513_3 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 511.0
CMS2_k127_6669513_4 Membrane protease subunits - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 411.0
CMS2_k127_6669513_5 Belongs to the bacterial histone-like protein family K03530 - - 0.0000000000000000000000000000000004175 133.0
CMS2_k127_6669513_6 Acetyltransferase (GNAT) domain K22479 - - 0.000003373 51.0
CMS2_k127_6669513_7 Belongs to the 'phage' integrase family K03111 - - 0.000007517 48.0
CMS2_k127_6687062_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1039.0
CMS2_k127_6687062_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 4.18e-203 637.0
CMS2_k127_6687062_10 Protein conserved in bacteria - - - 0.00000000000000000000008307 109.0
CMS2_k127_6687062_11 Protein conserved in bacteria - - - 0.00000000000000000002656 101.0
CMS2_k127_6687062_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 520.0
CMS2_k127_6687062_3 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 377.0
CMS2_k127_6687062_4 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 364.0
CMS2_k127_6687062_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005931 275.0
CMS2_k127_6687062_6 Belongs to the UPF0246 family K09861 - - 0.00000000000000000000000000000000000000000000000000000000000000001415 232.0
CMS2_k127_6687062_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000009215 189.0
CMS2_k127_6687062_8 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000004053 155.0
CMS2_k127_6687062_9 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000005381 132.0
CMS2_k127_6792718_0 Cation transporter/ATPase, N-terminus K01539 - 3.6.3.9 5.734e-271 854.0
CMS2_k127_6792718_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 337.0
CMS2_k127_6792718_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004158 259.0
CMS2_k127_6792718_3 Colicin V production protein - - - 0.0003029 50.0
CMS2_k127_6796682_0 cytochrome c - - - 0.0 1151.0
CMS2_k127_6796682_1 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 540.0
CMS2_k127_6796682_2 Belongs to the KdsA family K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 397.0
CMS2_k127_6796682_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002731 275.0
CMS2_k127_6796682_4 membrane K15270 - - 0.000000000000000000000000000000000000000000000000000000000001762 213.0
CMS2_k127_6796682_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000004171 181.0
CMS2_k127_6796682_6 Peptidase, M16 - - - 0.000000000000008132 77.0
CMS2_k127_6836658_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.212e-307 953.0
CMS2_k127_6836658_1 Sulfatase - - - 3.834e-224 711.0
CMS2_k127_6836658_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 297.0
CMS2_k127_6836658_11 lipopolysaccharide heptosyltransferase K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001183 286.0
CMS2_k127_6836658_12 Chemotaxis protein cheY K03413 - - 0.000000000000000000000000000000000000000000000000000000000000002513 218.0
CMS2_k127_6836658_13 lipid a biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000002522 201.0
CMS2_k127_6836658_14 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000005516 171.0
CMS2_k127_6836658_15 - - - - 0.0000000000000000000000000000002585 126.0
CMS2_k127_6836658_17 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000001913 57.0
CMS2_k127_6836658_2 Sulfatase K03760 - 2.7.8.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 571.0
CMS2_k127_6836658_3 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 567.0
CMS2_k127_6836658_4 aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 488.0
CMS2_k127_6836658_5 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 437.0
CMS2_k127_6836658_6 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 393.0
CMS2_k127_6836658_7 General glycosylation pathway protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 381.0
CMS2_k127_6836658_8 Nucleotidyltransferase DNA polymerase involved in DNA repair K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 379.0
CMS2_k127_6836658_9 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 316.0
CMS2_k127_6842264_0 ATPase (AAA - - - 3.256e-253 793.0
CMS2_k127_6842264_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 584.0
CMS2_k127_6842264_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 474.0
CMS2_k127_6842264_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 360.0
CMS2_k127_6842264_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 332.0
CMS2_k127_6842264_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000001002 124.0
CMS2_k127_6842264_6 - - - - 0.0000000000000000000000006938 111.0
CMS2_k127_6842264_7 NADH dehydrogenase (ubiquinone) activity K00330 - 1.6.5.3 0.000000000000004897 79.0
CMS2_k127_6866696_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 331.0
CMS2_k127_6866696_1 Belongs to the DEAD box helicase family K05591 GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001151 259.0
CMS2_k127_6866696_2 PFAM Methyltransferase type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004895 256.0
CMS2_k127_6866696_3 RNase H - - - 0.0000000000000000000000000000000000000000000001067 177.0
CMS2_k127_6866696_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000002023 184.0
CMS2_k127_6866696_6 DNA-binding protein VF530 - - - 0.000000000000000000000000005611 111.0
CMS2_k127_6866696_7 regulation of translation K03530,K05788 - - 0.000001086 54.0
CMS2_k127_6866696_8 Lysin motif - - - 0.0004807 51.0
CMS2_k127_6866696_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0008467 51.0
CMS2_k127_6873252_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 8.046e-196 617.0
CMS2_k127_6873252_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 520.0
CMS2_k127_6873252_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 423.0
CMS2_k127_6873252_3 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000005773 222.0
CMS2_k127_6873252_4 DNA replication regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000006926 223.0
CMS2_k127_6873252_5 DNA polymerase III K02341 - 2.7.7.7 0.000000000000000000000000000000002232 135.0
CMS2_k127_6888069_0 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 533.0
CMS2_k127_6888069_1 PepSY-associated TM region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 353.0
CMS2_k127_6888069_2 TonB-dependent copper receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 339.0
CMS2_k127_6888069_3 cheY-homologous receiver domain - - - 0.000003938 55.0
CMS2_k127_6924801_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 4.414e-266 821.0
CMS2_k127_6924801_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 544.0
CMS2_k127_6924801_10 LysM domain - - - 0.000009517 58.0
CMS2_k127_6924801_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 425.0
CMS2_k127_6924801_3 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 409.0
CMS2_k127_6924801_4 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 386.0
CMS2_k127_6924801_5 Belongs to the pseudouridine synthase RluA family K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 336.0
CMS2_k127_6924801_6 phosphorylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004125 239.0
CMS2_k127_6924801_7 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000002496 145.0
CMS2_k127_6924801_8 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000002327 69.0
CMS2_k127_6924801_9 Chemotaxis phosphatase CheX - - - 0.000000003199 69.0
CMS2_k127_6926131_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1048.0
CMS2_k127_6926131_1 Cytochrome c biogenesis protein - - - 1.047e-284 910.0
CMS2_k127_6926131_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.675e-226 706.0
CMS2_k127_6926131_3 Signal transduction protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 318.0
CMS2_k127_6926131_4 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000000001405 188.0
CMS2_k127_6926131_5 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.0003852 45.0
CMS2_k127_6990940_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 6.889e-295 921.0
CMS2_k127_6990940_1 type II secretion system protein E K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 544.0
CMS2_k127_6990940_2 phosphohydrolase (DHH superfamily) K07097 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 394.0
CMS2_k127_6990940_3 Type II secretion system K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005809 263.0
CMS2_k127_6990940_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000002428 179.0
CMS2_k127_6990940_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000001385 145.0
CMS2_k127_6990940_6 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000001421 125.0
CMS2_k127_6990940_7 general secretion pathway protein K02456,K02458 - - 0.0001615 51.0
CMS2_k127_7013946_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 1.799e-242 761.0
CMS2_k127_7013946_1 Type II secretion system K02455,K12278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 479.0
CMS2_k127_7013946_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 353.0
CMS2_k127_7013946_3 Histidine kinase K11527 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 319.0
CMS2_k127_7013946_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002948 261.0
CMS2_k127_7013946_5 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001334 246.0
CMS2_k127_7013946_6 proteins homologs of microcin C7 resistance protein MccF - - - 0.000000000000000000000000000000000000000000000000000000001203 205.0
CMS2_k127_7013946_7 GatB Yqey family protein K09117 - - 0.0000000000000000000000000000000000000000000007339 171.0
CMS2_k127_7013946_8 ATPase (AAA K01714,K12283 - 4.3.3.7 0.000000000000001616 78.0
CMS2_k127_71472_0 Epimerase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 289.0
CMS2_k127_71472_1 TIGRFAM cob(II)yrinic acid a,c-diamide reductase K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008683 274.0
CMS2_k127_71472_10 Protein of unknown function (DUF2892) - - - 0.000000000000001101 82.0
CMS2_k127_71472_11 Protein of unknown function (DUF2892) - - - 0.00000000002077 66.0
CMS2_k127_71472_2 chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000006393 225.0
CMS2_k127_71472_3 Transcriptional regulator K03892 - - 0.0000000000000000000000000000000000000000000000000000000000001385 214.0
CMS2_k127_71472_4 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000414 207.0
CMS2_k127_71472_5 - - - - 0.00000000000000000000000000000000000000000000000000001106 194.0
CMS2_k127_71472_6 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000002353 191.0
CMS2_k127_71472_7 superoxide reductase activity K05919 - 1.15.1.2 0.00000000000000000000000000006835 122.0
CMS2_k127_71472_8 Protein of unknown function, DUF255 - - - 0.000000000000000000000003345 106.0
CMS2_k127_71472_9 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000000000375 102.0
CMS2_k127_733854_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 303.0
CMS2_k127_733854_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001223 249.0
CMS2_k127_733854_2 Signal transduction protein - - - 0.00000000000000000000000000000005287 142.0
CMS2_k127_733854_3 Belongs to the HpcH HpaI aldolase family - - - 0.000000000000000000000000000001061 126.0
CMS2_k127_733854_4 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000017 118.0
CMS2_k127_733854_5 - - - - 0.00000000000000000002247 96.0
CMS2_k127_733854_6 Histidine kinase K03407 - 2.7.13.3 0.0000002486 63.0
CMS2_k127_733854_7 - - - - 0.0001261 51.0
CMS2_k127_73975_0 Elongation factor K03833 - - 2.036e-274 855.0
CMS2_k127_73975_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 562.0
CMS2_k127_73975_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 541.0
CMS2_k127_73975_3 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 424.0
CMS2_k127_73975_4 methyltransferase K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 314.0
CMS2_k127_73975_5 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 291.0
CMS2_k127_73975_6 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001721 261.0
CMS2_k127_73975_7 protein-glutamate methylesterase K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000611 119.0
CMS2_k127_73975_8 - - - - 0.0000000000000000000000000000731 122.0
CMS2_k127_7926_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1261.0
CMS2_k127_7926_1 cation efflux system protein K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 337.0
CMS2_k127_7926_2 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000002124 127.0
CMS2_k127_794815_0 Hydrogenase-4, component G K14090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008887 588.0
CMS2_k127_794815_1 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K14086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 583.0
CMS2_k127_794815_2 NADH dehydrogenase K14087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 384.0
CMS2_k127_794815_3 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 299.0
CMS2_k127_794815_4 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000000000000000000000005354 157.0
CMS2_k127_854458_0 DNA polymerase K02337 - 2.7.7.7 0.0 1830.0
CMS2_k127_854458_1 PFAM HI0933 family protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 384.0
CMS2_k127_854458_2 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 320.0
CMS2_k127_854458_3 Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) K00557 - 2.1.1.35 0.000000000000000000000000000002357 121.0
CMS2_k127_854458_4 cheY-homologous receiver domain - - - 0.00000000000000009872 84.0
CMS2_k127_854458_5 - - - - 0.00000000000002026 78.0
CMS2_k127_854458_6 protein involved in exopolysaccharide biosynthesis - - - 0.0000006207 59.0
CMS2_k127_883016_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 466.0
CMS2_k127_883016_1 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 361.0
CMS2_k127_883016_2 - - - - 0.0000002455 57.0
CMS2_k127_889025_0 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 435.0
CMS2_k127_889025_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 317.0
CMS2_k127_889025_2 phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 300.0
CMS2_k127_889025_3 COG0803 ABC-type metal ion transport system, periplasmic component surface adhesin K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000205 286.0
CMS2_k127_889025_4 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000002196 187.0
CMS2_k127_889025_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000123 177.0
CMS2_k127_889025_6 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000003757 131.0
CMS2_k127_889025_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0002972 50.0
CMS2_k127_894201_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1703.0
CMS2_k127_894201_1 Belongs to the DNA mismatch repair MutS family K03555 - - 6.16e-314 980.0
CMS2_k127_894201_10 Rod shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000001033 241.0
CMS2_k127_894201_11 - - - - 0.00000000000000000000000000000000000001151 151.0
CMS2_k127_894201_12 L-threonylcarbamoyladenylate synthase - - - 0.00000000000000000000000000000000001055 140.0
CMS2_k127_894201_13 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000001087 117.0
CMS2_k127_894201_14 - - - - 0.0000000000006952 75.0
CMS2_k127_894201_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 8.136e-202 634.0
CMS2_k127_894201_3 chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 612.0
CMS2_k127_894201_4 rod shape-determining protein mreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 585.0
CMS2_k127_894201_5 Glutathionylspermidine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 580.0
CMS2_k127_894201_6 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 429.0
CMS2_k127_894201_7 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 383.0
CMS2_k127_894201_8 component I K01665 - 2.6.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 349.0
CMS2_k127_894201_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0019171 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000006132 239.0
CMS2_k127_89983_0 COG0474 Cation transport ATPase - - - 0.0 1041.0
CMS2_k127_89983_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.555e-208 663.0
CMS2_k127_89983_10 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000002434 212.0
CMS2_k127_89983_11 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000004184 209.0
CMS2_k127_89983_12 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000002259 169.0
CMS2_k127_89983_13 Cupin domain K11312 - - 0.00000000000000000000000000002471 119.0
CMS2_k127_89983_14 glyoxalase III activity - - - 0.00000000000000000000000001802 115.0
CMS2_k127_89983_15 PFAM EAL domain - - - 0.0000000000000000000000002212 119.0
CMS2_k127_89983_16 Regulator of ribonuclease activity B - - - 0.000000000000000000000003548 105.0
CMS2_k127_89983_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 548.0
CMS2_k127_89983_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 535.0
CMS2_k127_89983_4 (GGDEF) domain K21024 - 3.1.4.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 553.0
CMS2_k127_89983_5 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 484.0
CMS2_k127_89983_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 313.0
CMS2_k127_89983_7 nucleotide-binding protein implicated in inhibition of septum formation K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003831 268.0
CMS2_k127_89983_8 GHKL domain - - - 0.0000000000000000000000000000000000000000000000000000000001001 219.0
CMS2_k127_89983_9 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000001203 208.0
CMS2_k127_942494_0 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 492.0
CMS2_k127_942494_1 PAS domain - - - 0.0000000000000000000000000000000000000000000000000001322 198.0
CMS2_k127_942494_2 - - - - 0.00000000000000008147 81.0
CMS2_k127_942494_3 - - - - 0.00000002945 55.0
CMS2_k127_942494_4 - - - - 0.0000002604 52.0
CMS2_k127_942494_5 - - - - 0.00000111 51.0
CMS2_k127_968872_0 Belongs to the aldehyde dehydrogenase family - - - 1.7e-232 726.0
CMS2_k127_968872_1 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002063 254.0
CMS2_k127_968872_2 5'-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000001832 237.0
CMS2_k127_981572_0 Radical SAM - - - 7.069e-203 639.0
CMS2_k127_981572_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007542 524.0
CMS2_k127_981572_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 446.0
CMS2_k127_981572_3 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 372.0
CMS2_k127_981572_4 Protein of unknown function (DUF3584) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 330.0
CMS2_k127_981572_5 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000000000000000000000000000449 151.0
CMS2_k127_981572_6 - - - - 0.0000000000000000000000000000000000296 137.0
CMS2_k127_981572_7 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000000006105 137.0
CMS2_k127_998844_0 Type I secretion system ATPase K12541 - - 1.371e-243 771.0
CMS2_k127_998844_1 type I secretion membrane fusion protein, HlyD family K02022,K12542 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 432.0
CMS2_k127_998844_2 Outer membrane efflux protein K12543 - - 0.00000000000000000000000000000000000000000000000000000000004738 223.0
CMS2_k127_998844_3 PFAM FecR protein - - - 0.000000000000000000000000000008576 126.0